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    TUTORIAL 2: Introduction To Metabolism: Characteristics

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    RaysonChoo
    This document contains a tutorial on metabolism. It contrasts catabolic, anabolic, and amphibolic pathways and provides examples of each. It also analyzes a redox reaction involved in fatty acid synthesis, identifying the electron donors, acceptors, substances getting oxidized and reduced, and redox pairs. Finally, it justifies why storing large amounts of ATP is not an effective energy storage strategy and explains to someone trying to lose weight that their metabolism is likely not the primary cause of weight gain and that quick fix diets and supplements may not be effective.

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    TUTORIAL 2: Introduction To Metabolism: Characteristics

    Uploaded by

    RaysonChoo
    46 views4 pages
    This document contains a tutorial on metabolism. It contrasts catabolic, anabolic, and amphibolic pathways and provides examples of each. It also analyzes a redox reaction involved in fatty acid synthesis, identifying the electron donors, acceptors, substances getting oxidized and reduced, and redox pairs. Finally, it justifies why storing large amounts of ATP is not an effective energy storage strategy and explains to someone trying to lose weight that their metabolism is likely not the primary cause of weight gain and that quick fix diets and supplements may not be effective.

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    PBPN - T2

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    This document contains a tutorial on metabolism. It contrasts catabolic, anabolic, and amphibolic pathways and provides examples of each. It also analyzes a redox reaction involved in fatty acid synthesis, identifying the electron donors, acceptors, substances getting oxidized and reduced, and redox pairs. Finally, it justifies why storing large amounts of ATP is not an effective energy storage strategy and explains to someone trying to lose weight that their metabolism is likely not the primary cause of weight gain and that quick fix diets and supplements may not be effective.

    Copyright:

    © All Rights Reserved
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    46 views4 pages

    TUTORIAL 2: Introduction To Metabolism: Characteristics

    Uploaded by

    RaysonChoo
    This document contains a tutorial on metabolism. It contrasts catabolic, anabolic, and amphibolic pathways and provides examples of each. It also analyzes a redox reaction involved in fatty acid synthesis, identifying the electron donors, acceptors, substances getting oxidized and reduced, and redox pairs. Finally, it justifies why storing large amounts of ATP is not an effective energy storage strategy and explains to someone trying to lose weight that their metabolism is likely not the primary cause of weight gain and that quick fix diets and supplements may not be effective.

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    © All Rights Reserved
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    PBPN (ANT2004)

    TUTORIAL 2: Introduction to Metabolism

    Name:__________________________ Tutorial Class: ________ Date:_____________

    1. Contrast between the following pathways:

    Catabolic Anabolic Amphibolic


    Characteristics
    Pathways Pathways Pathways
    Simple or complex Complex to Simple Simple to Both
    molecules produced? Complex
    Exergonic or Exergonic Endogonic Both
    endergonic?
    ADP to ATP ATP to ADP Both
    ATP/ADP generated?

    Oxidative form Reductive form Both


    Oxidative or reductive?
    NaDH, NADPH, NAD+, NADP+,
    Name coenzymes formed
    FADH2 FAD
    End in lysis End in genesis
    Names end with …

    Glycogenolysis, Glycogenesis, TCA cycle


    lipolysis, lipogenesis,
    Specific example
    glycolysis, ketogenesis
    proteolysis, etc

    2. Analyse the redox reaction represented below.


    NADPH NADP+
    H S - CE + H+ HS- CE

    FATTY ACID
    SYNTHASE
    CH3 – CH = CH – CO – S - ACP
    - CH3 – CH 2 – CH2 – CO – S - ACP

    Trans-butenoyl-ACP Butyryl-ACP

    i. The electron donor is: NADPH


    ii. The electron acceptor is: trans-butenoyl-
    iii. The substance getting oxidized is: NADPH
    iv. The substance getting reduced is: trans-butenoyl-acp
    v. The oxidizing agent/oxidant is: trans-butenoyl-acp
    vi. The reducing agent/reductant is: NADPH
    vii. Two redox pairs are: NADP+/NADPH
    and trans-butenoyl-acp/ butyryl-acp

    Tut2/April2019 1
    PBPN (ANT2004)

    3. Do you agree with following statement? Justify your answer.


    “As ATP is our energy currency, we should store lots of ATP to ensure a constant energy
    supply”. (7 marks)
     ATP is a high energy molecule with very unstable/weak phosphate bonds
     Not a preferred storage form of energy
     For immediate needs, our body stores energy in the form of phosphocreatine
     The coupling between the ATP-ADP cycle and the creatine-phosphocreatine (Cr-PCr)
    system maintain a constant supply of energy in the cell
     Phosphocreatine + ADP <-> creatine + ATP
     Enzyme: creatine kinase
     Our body ultimately stores energy in the form of glycogen and fats/adipose tissue.

    4. Janet has been putting on weight the past few weeks and she blames it on her slow
    metabolism. She was told that coconut oil, ginger and coffee speeds up metabolism and
    wonders if adding these to her diet will help her lose weight.....
    Help explain to Janet, separating the myths from the facts! (8 marks)

     Metabolism = all the chemical processes to keep one alive and body system functioning.
    These processes require energy.
     The minimum amount of energy one requires for these processes is called basal
    metabolism. Basal metabolism rate (BMR) accounts for 40-70% of one’s energy needs,
    depending on age and lifestyle.
     One way to determine one’s daily energy needs is using the harris-benedict equation.
    Body size, age and gender determine metabolism rate
     Younger people, men and those with more muscle mass have higher metabolic
    rates.
     Some medical conditions slow down one’s metabolism – hypothyroidism, cushing’s
    syndrome
     More often than not, people gain weight because of overconsumption of calories.
     The evidence behind the claims (coconut oil, ginger, coffee) are not strong. In fact,
    adding calorie-dense coconut oil to her diet will lead to further weight gain
     Quick fix diets can cause one to lose muscles – this will slow down metabolism
     Being physically active burns away calories; especially strength training that builds up
    muscle mass.

    Tut2/April2019 2
    PBPN (ANT2004)

    Tut2/April2019 3
    PBPN (ANT2004)

    Tut2/April2019 4

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