PHARMACODYNAMICS MCQ
PHARMACODYNAMICS MCQ
PHARMACODYNAMICS MCQ
d) Drug interactions
4. Pick out the answer which is the most appropriate to the term “receptor”
c) Active macromolecular components of a cell or an organism which a drug molecule has to combine
with in
a) Only receptors
c) Only carriers
b) Interacts with the receptor and initiates changes in cell function, producing various effects
8. If an agonist can produce maximal effects and has high efficacy it’s called:
a) Partial agonist
b) Antagonist
c) Agonist-antagonist
d) Full agonist
9. If an agonist can produce submaximal effects and has moderate efficacy it’s called:
a) Partial agonist
b) Antagonist
c) Agonist-antagonist
d) Full agonist
10. An antagonist is a substance that:
a) Binds to the receptors and initiates changes in cell function, producing maximal effect
b) Binds to the receptors and initiates changes in cell function, producing submaximal effect
b) Binds to the same receptor site and progressively inhibits the agonist response
12. The substance binding to one receptor subtype as an agonist and to another as an antagonist is
called:
a) Competitive antagonist
b) Irreversible antagonist
c) Agonist-antagonist
d) Partial agonist
a) Ionic bonds
b) Hydrogen bonds
c) Covalent bonds
14. Tick the substances whose mechanisms are based on interaction with ion channels
17. Which effect may lead to toxic reactions when a drug is taken continuously or repeatedly?
a) Refractoriness
b) Cumulative effect
c) Tolerance
d) Tachyphylaxis
18. What term is used to describe a more gradual decrease in responsiveness to a drug, taking days or
weeks to develop?
a) Refractoriness
b) Cumulative effect
c) Tolerance
d) Tachyphylaxis
19. What term is used to describe a decrease in responsiveness to a drug which develops in a few
minutes?
a) Refractoriness
b) Cumulative effect
c) Tolerance
d) Tachyphylaxis
20. Tachyphylaxis is:
21. Drug resistance is a term used to describe the loss of effectiveness of antimicrobial or antitumour
drugs. This
consideration is:
a) True
b) False
a) Drug dependence
a) Diminished absorption
a) True
b) False
26. The situation when failure to continue administering the drug results in serious psychological and
somatic disturbances is called?
a) Tachyphylaxis
b) Sensibilization
c) Abstinence syndrome
d) Idiosyncrasy
27. What is the type of drug-to-drug interaction which is connected with processes of absorption,
biotransformation,
a) Pharmacodynamic interaction
c) Pharmaceutical interaction
d) Pharmacokinetic interaction
28. What is the type of drug-to-drug interaction which is the result of interaction at receptor, cell, enzyme
or organ level?
a) Pharmacodynamic interaction
c) Pharmaceutical interaction
d) Pharmacokinetic interaction
29. What phenomenon can occur in case of using a combination of drugs?
a) Tolerance
b) Tachyphylaxis
c) Accumulation
d) Synergism
30. If two drugs with the same effect, taken together, produce an effect that is equal in magnitude to the
sum of the effects of the drugs given individually, it is called as:
a) Antagonism
b) Potentiation
c) Additive effect
b) Hypersensitivity to a drug
a) Summarized
b) Potentiated
c) Additive
d) Competitive
b) two drugs combine with one another to form a more active compound
c) two drugs combine with one another to form a more water soluble compound
d) two drugs combine with one another to form a more fat soluble compound
34. A teratogenic action is:
35. Characteristic unwanted reaction which isn’t related to a dose or to a pharmacodynamic property of a
drug is called:
a) Idiosyncrasy
b) Hypersensitivity
c) Tolerance
d) Teratogenic action
a) A ratio used to evaluate the safety and usefulness of a drug for indication