Preferred Reporting Items For Systematic Reviews and Meta-Analyses
Preferred Reporting Items For Systematic Reviews and Meta-Analyses
Contents
History[edit]
In 1987, Cynthia Mulrow examined for the first time the methodological quality of a sample of 50
review articles published in four leading medical journals between 1985 and 1986 She found that
none met a set of eight explicit scientific criteria, and that the lack of quality assessment of
primary studies was a major pitfall in these reviews.[3] In 1987, Sacks and colleagues [4] evaluated
the quality of 83 meta-analyses, using a scoring method that considered 23 items in six major
areas: study design, combinability, control of bias, statistical analysis, sensitivity analysis, and
application of results. Results of this research showed that reporting was generally poor; and
pointed out an urgent need for improved methods in literature searching, quality evaluation of
trials, and synthesizing of the results.
In 1996, an international group of 30 clinical epidemiologists, clinicians, statisticians, editors, and
researchers convened The Quality of Reporting of Meta-analyses (QUOROM) conference to
address standards for improving the quality of reporting of meta-analyses of clinical randomized
controlled trials (RCTs) [5]
The conference resulted in the QUOROM, a checklist, and a flow diagram that described the
preferred way to present the abstract, introduction, methods, results, and discussion sections of
a report of a systematic review or a meta-analysis. Eight of the original 18 items formed the basis
of the QUOROM reporting. Evaluation of reporting was organized into headings and
subheadings regarding searches, selection, validity assessment, data abstraction, study
characteristics, and quantitative data synthesis.
In 2009, the QUOROM was updated to address several conceptual and practical advances in the
science of systematic reviews, and was renamed PRISMA (Preferred Reporting Items of
Systematic reviews and Meta-Analyses).[6]
PRISMA components[edit]
The PRISMA checklist[edit]
The checklist includes 27 items pertaining to the content of a systematic review and meta-
analysis, which include the title, abstract, methods, results, discussion and funding.