Evidence-Based Practice: Elizabeth R. Cluett
Evidence-Based Practice: Elizabeth R. Cluett
Evidence-Based Practice: Elizabeth R. Cluett
2
Evidence-based practice
Elizabeth R. Cluett
KEY CONTENT
◆ Origins
◆ The purpose
◆ The process of evidence-based practice
The EPB question
Searching and accessing the evidence
Types of literature and the hierarchy of evidence
Search processes, gateways and databases
Key words, combinations and criteria
Critical appraisal of the evidence
Application of the best evidence to practice
Full and short EPB processes
◆ The evidence for EBP
Advantages
Disadvantages
◆ Evidence-based practice and policy
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INTRODUCTION
The current expectation of the maternity services, along with all other health and
social care, is the provision of high-quality, clinically effective and client-centred care
(Department of Health 1993, 1997, 1998, 2004a, NHS Executive 2000). Evidence-
based practice (EBP) is fundamental to this, being embedded within clinical governance
(NHS Executive 1999). It is therefore not surprising that all midwives are required
to base their practice on the best available evidence (Nursing and Midwifery Council
2004). This means that all midwives must understand what EBP is and is not, and
how it informs the practice of midwifery. This chapter will explore the development
and nature of EBP and consider each of the key elements of the EBP process in some
detail. The strengths and weaknesses of EBP will be explored, highlighting some of
the issues surrounding EBP and its widespread implementation.
ORIGINS
‘Evidence-based medicine’ (EBM) was coined and defined by Sackett et al in
1996 as:
The conscientious, explicit and judicious use of the current best evidence
in making decisions about the care of individual patients. (Sackett et al
1996, p. 169)
This became evidence-based practice, as the principles and process were adopted
by many disciplines in health and social care. This suggests EBP is a modern concept,
but this could be disputed, as although the phrase is only a decade old, EBP evolved
over many years. As research, methods of data collection including audit and com-
munication technologies increased, the volume of information available on some
topics made it difficult for practitioners to access and assimilate. One management
strategy to deal with this was to bring the information together by topic and make it
readily available. In the early 1970s, Archie Cochrane recognized the need to collate
research data from randomized controlled trials (RCTs), critique it and conclude what
was effective care, so that limited resources could be used wisely (Cochrane 1972 cited
in Reynolds 2000). This led to the systematic review. The work of Iain Chalmers
and like-minded colleagues led the way in healthcare, providing professionals within
the maternity services with a register of RCTs and a database of what care options
were effective, not effective, or of unknown value based on systematic reviews of
RCTs on each topic (Chalmers et al 1989). The publication of these two volumes
provided an accessible and essential reference text. Technological advances in world-
wide communication, the internet, meant this was soon followed by quarterly
updated, online resources known as the Cochrane Library, now covering most aspects
of healthcare (www.thecochranelibrary.com).
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Evidence-based practice ◆ 35
Around the same time the educational approach, ‘problem-based learning’ – also
called enquiry-based learning – was introduced into the curriculum of health profes-
sionals. First described by McMaster University in Canada (Evidence Based Medicine
Working Group 1992), although Sackett et al (2000) suggest earlier examples, it enables
students to be active and lifelong learners. Through facilitation students identify
for themselves what they need to know in order to provide high-quality care, and
develop the skills to access knowledge, appraise it, and make decisions based on the
conclusions drawn, ultimately developing the competencies to practise (Cleverley 2003,
Price 2003).
Trinder (2000) suggests that the development of EBP is more complex, being
interwoven with the complex social fabric of the era in which it was born. At a time
when most people in the developed world can expect a long and high-quality life, it
could seem surprising that health is such a concern to individuals, governments and
society in general. The greater knowledge base of the populace, their health and
wealth, has contributed to a consumer-based society, where the expectation is of
choice and control, where risk is quantified and controlled, and health professionals
are questioned and challenged to justify every action in terms of its basis in science,
effectiveness and efficiency (Trinder 2000). Thus the philosophy of EBP meets a
deep need in professionals and society, alike. This may be the reason why EBP has
been so widely and swiftly adopted in all spheres of healthcare, and many other
domains, such as education, management and social work (Trinder 2000).
THE PURPOSE
The aim of EBP is to do the right thing, at the right time, for the right person,
in other words ensure quality care for the individual client. This is achieved by eval-
uating ideas, practices and previous events and applying the learning achieved
to future practice. An illustration of this is the confidential enquiry into maternal
deaths in the UK (Confidential Enquiry into Maternal and Child Health 2004). This
report highlighted how maternal mortality has decreased over the past 50 years,
and suggested that some of this improvement could be attributed to changes in
practice as a result of previous reports. This illustrates the key principle of EBP:
the evaluation of what is known and done, and using that to decide what should
influence what is done next.
Gabby and le May (2004) explored how professionals used formal evidence
sources such as research, and describe a pyramid with four levels of EBP. The
foundation layer is described as a social movement, but could be considered
as representing the underpinning philosophy on which everything is based. The
second layer refers to national and local EBP policies and/or guidelines. This is the
EBP process, the practical interpretation of the concepts. The third layer represents
the practitioners who utilize the concepts and processes. The clients receiving care
based on the current best evidence, which is related to their individual circumstances,
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complete the layers. These four layers, however, do not consider how the philosophy
is converted into policies, or how practitioners adopt the policies and make EBP
information and care available to clients. Neither are the levels interdependent.
Professionals may use policies/guidelines without subscribing to, or understanding
the EBP philosophy, while clients may receive the best care, without anyone having
considered EBP. The pyramid could also be turned upside down as it could be argued
that it is consumers that are contributing to the upsurge of EBP. Clients increasingly
demand high-quality care, with expectations increasing each year (Department of
Health 2004b). There is increased emphasis on partnership, working with clients in the
provision of a service that is responsive to their needs (Department of Health 2003).
Therefore a circular relationship between clients, practitioners and evidence may be
a useful representation of the interaction of each within an overall philosophy of EBP
(Fig. 2.1). This is congruent with the principles of effective and high-quality care, in which
midwives, and all practitioners, strive to provide the very best care to each individual.
As Sackett et al (2000) emphasize, EBP is more than just the best evidence, it is the
integration of best evidence with high-quality clinical skills, such as communication
and assessment, as well as the application of evidence to the particular belief systems,
values and context of the client’s life.
Evidence is forever changing in the light of new research, new technology, new
ideas, as well as old ideas and options put together in new ways. This is challenging
as it means best practice cannot conclusively and finally be established. The onus is
Evidence-based
practice philosophy
Practitioners
Clients and
service
Evidence
Evidence-based practice ◆ 37
on each practitioner to establish the evidence for each case. An important feature of
EBP is the way it is dynamic and open to reviewing, its purpose to be a way of con-
stantly updating practice. Therefore all midwives need to develop the skills required
for EBP practice. These skills are the same skills that midwives need for midwifery
care, some of which are listed in Box 2.1 and were identified in the Introduction to
this book. There is a widely accepted EBP process. The process must be transparent
and open to the scrutiny of other professionals and the public. The next sections
explore the process, or practical application, of EBP.
The following sections will explore what is involved in each of these five steps.
To help recall these four features the mnemonic PICO may help:
P = person (originally patient) or target population
I = issue/intervention
C = comparison
O = outcome.
Box 2.2 provides examples and suggestions of topics that could be converted into
several EBP questions.
The importance of asking the right question is highlighted by Bastin (2004).
Evidence on the administration of bromocriptine to suppress lactation suggested
effectiveness, but later it was discovered that it increased mortality and morbidity.
Perhaps the EBP process to establish the quality of all the evidence was flawed but
much more likely the wrong question was asked, or there was an absence of evidence.
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Evidence-based practice ◆ 39
There are two sources of evidence, people and literature, although they are often
interrelated, as no practice occurs in a vacuum. Accessing people means participating
in professional and interprofessional conversations, talking to women and consumer
groups, attending conferences and engaging with researchers, educationalists, managers
and those who shape policy at all levels. Online networks, covering midwifery research,
normal birth and more general email communication networks, make this possible on
a national and global scale previously unheard of. Accessing such networks is usually
a relatively simple matter of registering and then getting online to the network of
your choice, having heard of/been given the contact point of such a network through
colleagues.
The literature search can start in your local health services library or online. Before
you embark on a search it is useful to understand the main types of literature and their
relationship to one another.
Types of literature
Literature is classified as primary or secondary. Primary literature refers to original
sources of information. Secondary literature includes systematic reviews, reviews,
guidelines/policies, editorials, opinions, critiques, and any information that is a recon-
sideration of primary data. Some types of literature can be either primary or secondary.
Published letters, for example, may be commenting on a previously published study,
or provide original data from another unit supporting or refuting a study, or even
highlighting a completely new point. There is also ‘grey’ literature, information that
may be in the public domain but has not yet been published, and includes data/
evidence held within theses, institutional reports and research data held by individual
researchers. Accessing grey literature is important, as there is a publication bias. This
is because the results of investigations that are particularly noteworthy, fashionable, con-
troversial, have renowned authorship, or are in some other way unique, are published,
whereas repeat studies, studies with no definitive conclusions, or less successfully
articulated data are not published. Such data is likely to be missed in many search
strategies, giving the potential for an incomplete evidence review and hence less pow-
erful or even erroneous conclusions. Thus although most of this section deals with
acquiring evidence from literature sources, it is also important to remember that
people are a vital resource. Speaking to experts on a topic, networking within the area of
interest may provide contacts and links to invaluable sources of evidence. This additional
time investment is warranted in terms of the quality of the finished evidence-based
review.
Hierarchy of evidence
Primary sources of evidence are considered superior to other forms of evidence and
the most important primary source is research findings. However, not all research is
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Evidence-based practice ◆ 41
valued to the same degree. This led to the development of a hierarchy of evidence,
with an expectation that practitioners will base their practice on the best evidence as
described by a hierarchy of evidence. One of the most cited hierarchies is that by
Guyatt et al (1995, p. 1802):
However, Evans (2003) cites examples from 1979 onwards. Most hierarchies rank
types of research findings according to which approach is most likely to provide valid
information on the effectiveness of a treatment/care option. Like Guyatt et al (1995),
such hierarchies usually have systematic review with meta-analysis at the top, followed
closely by RCTs. There are several other hierarchies of evidence for assessing studies
that provide evidence on diagnosis, prevention and economic evaluations (Evans
2003). Their focus remains quantitative. This does have disadvantages as some health
topics, even if they are about treatment/management effectiveness, may not be best
addressed within RCTs. For example, Kotaska (2004) suggests that vaginal breech birth
is too complex and multifaceted to be appropriately considered within trials alone.
Rietberg et al (2005) report how one RCT on breech birth has changed practice. It
is likely that the reasons for this are complicated and involved underlying professional
beliefs as well as the evidence. However, the emphasis on trials as the pinnacle of the
hierarchy of evidence could be seen to be encouraging an acceptance of this as the
‘gold standard’ in all circumstances, rather than reflecting on whether a particular
topic would be best considered from a different perspective, using different research
approaches.
It is acknowledged that quantitative studies cannot adequately explore the complex-
ities of the more social aspects of human life (Robson 2002). In midwifery this would
include areas such as the experience of birth, parenthood, or topics like social support,
transition to parenthood, uptake of antenatal screening, education, views on lifestyle
such as smoking and so on. These are more appropriately explored though qualitative
research approaches that seek to explore and understand the dynamics of human
nature, what makes them believe, think and act as they do. Qualitative evidence is not
within the hierarchy, a fact acknowledged by Sackett et al (2000), who indicates that
expertise in these forms of evidence is developing within nursing and midwifery. It is
possible that researchers within the qualitative domain need to engage in a dialogue
with both clinicians and proponents of EBP and debate the relationship between EBP
and qualitative research. Aslam (2000) provides a broader hierarchy, including personal
experience, clinical tradition and anecdote at the lowest end of the scale. This would
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seem to provide scope for the inclusion of reflexive activity (learning through reflection
‘in’ and ‘on’ practice (Schön 1987)), and analysis of tradition, experience and anecdotes
would appear to be within the spectrum of qualitative research, although this is not
explicitly stated. The alternative, a parallel qualitative hierarchy, seems problematic as
each approach offers a particular perspective with no one approach being better than
another.
Evidence-based practice ◆ 43
Database Details
Medline Arguably the primary source for biomedical
literature.The database is managed in America
and covers almost 4000 journals, with the
earliest dated from 1966, although literature
for this era is not complete.This database
can be accessed free from any location via
PubMed, and is also linked from most if not all
health institutions and universities.
Cumulative Index for Produced in America, and aims to meet the
Nursing and Allied information/evidence requirements of all
Health Literature nurses, midwives and allied professions.
(CINHAL)
Applied Social A general social sciences database, produced
Sciences Index and in the UK, covering topics including health,
Abstracts (ASSIA) education, sociology and psychology.
British Nursing The smallest database, but its strength is the
Index (BNI) UK focus, covering 220 British and English
nursing journals, which includes midwifery.
ZETOC Provides access to the contents of 20000
journals held by British Library across health
and social care, but also all forms of science,
humanities and arts.
PsycInfo Produced by the American Psychological
Association and covers lists of resources
related to predominantly psychology and
psychiatry, but also many related health and
social topics.
Evidence-based practice ◆ 45
Question: Does immersion in water during the first stage of labour reduce
the use of pharmacological analgesia?
Key words: labour – first stage, water immersion; pharmacological analgesia
Associated/alternative words: labor (American spelling), childbirth, birth,
waterbirth, bathing, bath(s), opioids, epidural analgesia
Limiters: human labour, English language, last 5 years, not reviews
Exercise for you to try
Identify the possible key words for a nuchal fold EBP question, or any of the
topic questions you developed in Box 2.2.
You could put the results of this activity in your portfolio if you are
developing expertise in EBP as part of your current learning objectives.
Possible answers can be found at the end of the chapter.
controlled trials. Whatever criteria you use, it is important to keep a record of them
so that you have a complete search history. This ensures the search strategy is trans-
parent to all and provides others with the opportunity of reviewing your work as an
audit process and validating it, so that they can replicate the search at a later date. In
addition, you must recognize the limitation of any limiting criteria you use. Moher
et al (2003) suggest that conducting a systematic review using trials published in
English only has the potential to give biased conclusions as key research on some
topics has only been published in other languages.
At the end of your search you should have a manageable list of references. How many
references make a manageable list depends on the time frame for your project; is it for
a particular client, a clinical guideline needed now, or an academic assignment due for
submission in 3 or 6 months? Whether or not it is funded and the number of people
involved are also key factors. All these factors can affect the reliability of the outcome.
Evidence-based practice ◆ 47
◆ Are there choices and is she in a position to understand them and make
them?
◆ The midwife (other health professionals):
◆ Is it within her sphere of practice?
◆ Has she the education, skills, confidence resources to offer/facilitate this care?
◆ Is it professionally and personally acceptable to provide such care or refer to
someone who can?
Finally you need to act and provide care based on the best evidence and the individual
circumstances of your client. The circle is then completed and restarted, as you should
review that practice, its appropriateness and outcomes, its effectiveness and efficiency,
from the perspective of the woman, midwife and service. From this will come new ideas,
and questions, the best evidence for which should be established, and so the EBP
process continues. This reflects a continuous quality improvement cycle, and is consis-
tent with a maternity service that aims for excellence, providing progressively higher-
quality, woman-centred care, and with a profession that espouses lifelong learning.
Application to practice may also raise management and service provision issues,
including:
There is not scope here to discuss these fully, but they are associated with clinical
governance, change management, professional and interprofessional working, to
name but a few issues. There may be barriers to implementation of the best evidence.
EBP is mostly likely to be successfully implemented in the context of a learning
organization, and achieving this is also about NHS health and social care manage-
ment, and how the government and the wider society envisage the service.
The EBP process does not always provide the ‘right’ answer. For some situations
there is no ‘right’ answer but two or more possibilities from which practitioners and
clients together must select the path most likely to be suitable. Sometimes there is no
evidence, or what is available is of limited use due to its age, the client groups used,
the practices of the location, or the uniqueness of the situation for which you are
seeking the evidence. This may always be the reality for the most complex and indi-
vidual cases. It is vital to remember that the absence of evidence is not evidence of no
benefit. No evidence implies we do not know what is best or worse. In this scenario
it is reasonable to provide your professional opinion, possibly based on experience,
which in itself is an important form of evidence. You will then need to emphasize that
it is only an opinion, and encourage the client to choose what she feels is best for
herself and her family.
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◆ local guidelines
◆ national guidelines, e.g. NSF and NICE guidelines, (www.doh.gov.uk)
◆ professional college guidelines. e.g. RCM position statements, RCOG green top
clinical guidelines (www.RCM.org.uk, www.RCOG.org.uk)
◆ systematic reviews published in:
◆ professional journals
◆ evidence-based practice journals
Full process
Frame a question
Apply to practice:
the client in her milieu
Evidence-based practice ◆ 49
Advantages
The widespread promotion and adoption of EBP is due to its perceived advantages,
in particular the goal of facilitating care based on the best evidence and available to
everyone, rather than being locality specific due to knowledge, expertise or funding.
The advantages of EBP include:
◆ explicit and transparent ways of working with less scope for misinterpretation
◆ information available to the public so that they can be genuinely involved in the
decision-making processes about their care
◆ clarification of what is known and what is not known to target further research.
All of which should lead to higher-quality and more effective care and a reduction
in the theory–practice gap.
The evidence to support these advantages is variable. It could be argued that evidence
for EBP is not needed, as it is ‘obvious’ that best practice is best, and always has been.
In this case what EBP provides is a set of skills and a way of working to access
what is the best evidence (Hunink 2004). There is some evidence that practitioners
who received education on EBP and its processes are more skilled in undertaking
EBP-related activity (Fritsche et al 2002).
Disadvantages
Straus and McAlister (2000) provide a commentary on the advantages and disadvan-
tages of EBP. The arguments highlighted by them remain the key concerns and include:
Some disadvantages of EBP are more statements of ongoing problems that are
common to all aspects of healthcare, such as lack of evidence, or poor evidence, or
lack of resources to provide the identified care. Although it could be argued that the
process of EBP makes it more likely that quality evidence will be identified to support
the obtaining of required resources.
The definition of EBM stresses the importance of ‘the patient values’ (Sackett et al
2000, p. 1). However, it could be argued that EBP is about generalizability. The best
evidence, hopefully the result of the EBP process, will tell practitioners what the likely
overall outcomes will be if 100 or 1000 individuals with a condition are cared for in
a particular way. The individual client is lost within the numbers; for example, you may
know that from 100 women using a birthing ball 70 will have a normal birth, but it
will not tell you if the woman in front of you will or not. This lack of individuality
has contributed to a widespread concern that EBP restricts choice (DaCruz 2002).
Lockwood (2004) explores individuality within the concept of EBM, considering
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Evidence-based practice ◆ 51
how, for many individuals it is the specific accounts and personal stories that help them
make decisions about their own lives, not just the evidence. Although Lockwood’s
study is based on data from women with breast cancer, many midwives are familiar
with women who make birth-related choices based on their beliefs, those of their
family and friends with no, or only secondary consideration of the evidence provided
by professionals. This suggests that while it is important to make the evidence of rec-
ommended management/care explicit and readily available, not all women will choose
that option. There tends to be an assumption that if all the evidence is made avail-
able, women will make the ‘right choice’ and that that choice will be consistent with
professional advice. This is clearly not always the case, and where client choices diverge
from professional advice there can be a tendency to be paternalistic, assuming it is a
lack of understanding or lack of information. Here the role of the midwife as the
woman’s advocate is vital, to ensure the client does have the information and is then
supported in her choice.
For women with complex pregnancies there is not enough specific evidence to
provide individualized risk assessment (Hawthorne and Blott 2004) and care is usu-
ally based on traditional/documentary evidence. The available evidence has to be
integrated with expert clinical experience from an interprofessional team, in the light
of the individual situation, needs, wishes and preferences. It may be that over-reliance
on EBP information will reduce professionals’ ability to practise creatively and meet
highly complex needs.
There is some concern that EBP guidelines will undermine practitioners’ autonomy
and lead to practitioners who are reluctant to provide care that does not conform to
guidelines. Hurwitz (2004) discusses the legal concept of negligence. He concludes
that while EBP guidelines could be used to indicate a standard of care and practitioners’
care could be evaluated against it, it is recognized that not all guidelines are perfect.
Therefore there are occasions when excellent care does not follow the guidelines and
equally there are occasions when high quality guidelines have been followed and care
has still been substandard. Professional judgement is always required.
Some believe EBP, or how it is currently understood and practised, devalues the
importance of practitioner experience and tacit knowledge (Goding and Edwards
2002). This can be extended to include forms of evidence lower, or absent, from the
hierarchy of evidence. It is argued that evidence from RCTs is so controlled that the
participants and clinical environment bear little resemblance to the average healthcare
setting and recipient (Schattner and Fletcher 2003). Therefore such evidence should
be skilfully evaluated alongside all other forms of evidence. It is vital to remember that
cohort studies identify patterns of health and areas of concern, prognosis and progres-
sion of conditions; case studies inform new management options or rare scenarios;
qualitative studies provide evidence on clients’ experience and care acceptability.
Experience and tacit knowledge can identify health needs and facilitate healthcare
provision. Each of these forms of evidence is vital and the emphasis on EBP and clinical
trials is not intended to be to the detriment of other evidence.
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CONCLUSION
Evidence-based practice is a philosophy and a process. It is logical, sensible and
scientific; there are frameworks and processes that meet a need for ‘certainty’ and
‘structure’ in many professionals and consumers alike. Healthcare, like life, is often
uncertain, and decision-making can be problematic. EBP is a way of helping with
everyday and tricky decisions that can be quantified and justified. Skilfully used,
EBP can enhance practice. So every midwife and health practitioner should:
◆ develop the skills associated with EBP
◆ remember EBP is a tool for high quality practice, it is not an end in itself.
EBP highlights that we do not know everything and practitioners need to be honest and
open, indicating where there is a dearth of information, or the evidence is incomplete,
inconclusive, weak, open to interpretation or in some way limited.This means
acknowledging, more than some professionals are used to, that we really practise in many
shades of grey and very rarely in black and white. It must also be acknowledged that EBP
has limitations as well as benefits.As yet, qualitative evidence is not incorporated
within EBP. EBP is a tool, achieving the skills of which provides many benefits to
practitioners, related to identifying, accessing, and evaluating evidence. However, it must
be done using a discerning, reflective and critical judgement, and applied to clinical
practice so that it is not an academic activity but a real practice development strategy.
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Evidence-based practice ◆ 53
CHAPTER SUMMARY
This chapter has defined evidence-based practice and explored its relation to
research.The process of EBP has been identified, and details provided on how to
successfully undertake the various stages of both the full and short EBP process.
There is a guide to developing clinically focused questions that can be answered
through the EBP process. Search strategies have be explained, highlighting the
different types of evidence, particularly within the literature, including suggestions
on how to effectively identify the evidence needed to answer specific questions.
The advantages and disadvantages of EBP have been discussed. Midwives strive
for high quality, holistic care for women and EBP can help to achieve this. It is not
intended as a process to restrict practice but rather to facilitate it. Midwives need
to use and contribute to the development of the EBP processes to enhance them
further.
cont’d
Alternative words: wellbeing, APGARs, cord gases (i.e. data which implies
safety)
Combination: nuchal fold AND fetus AND safety (will only identify articles
with all the terms included)
Safety OR wellbeing OR APGARs OR cord gases (will identify all articles
with one or more of these terms included)
Gas* – will identify gas, gases, gaseous, gashouse (some of which are useful,
some not)
F?tus will access fetus, foetus, fatal
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FURTHER READING
Hamer S, Collinson S 2003 Achieving evidence based practice. A handbook for practitioners, 3rd edn.
Baillière Tindall/RCN, London.
Brettle A, Grant M J 2004 Finding the evidence for practice. A workbook for health professionals.
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USEFUL WEBSITES
Centre for Evidence Based Medicine in Canada. Website supporting the Sackett et al (2000) evidence based
medicine textbook:
www.cebm.utoronte.ca/teach/materials
www.cebm.utoronto.ca/ebm
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Department of Health:
www.doh.gov.uk
www.doh.gov.uk/deliveringthebest/index
MIDIRS. Public and professionals’ access to maternity-related information:
www.infochoice.org
National electronic Library for Health:
www.nelh.gov.uk
Public Health Resource Unit for Critical Appraisal Skills programme:
www.phru.mhs.uk/~casp
Royal College of Midwives:
www.rcm.org.uk
Royal College of Obstetrics and Gynaecology:
www.rcog.org.uk
University of York for access to Centre for Reviews and Dissemination:
www.york.ac.uk