Cmb-Ppt-5-Endoplasmic Reticulum-Borja, Jayven C

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BORJA, JAYVEN C.

BSED 2B - SCIENCES
OBJECTIVES
• DEFINE WHAT IS ENDOPLASMIC
RETICULUM
• DESCRIBE THE BASIC
STRUCTURE OF ENDOPLASMIC
RETICULUM
• EXPLAIN THE KEY ROLE AND
MAIN FUNCTION OF ER IN CELL
DEFINING ENDOPLASMIC RETICULUM
The endoplasmic reticulum
(ER) is a network of flat and Endoplasmic means
vesicular structures which “within the plasm”
extends throughout the and reticulum
cytoplasm in plant and animal mean“network”
cells.
These sacs and tubules are
all interconnected by a single
continuous membrane so that the
organelle has only one large,
highly convoluted and complexly
arranged lumen (internal space).
It is connected to the
double-layered nuclear envelope.
ENDOPLASMIC RETICULUM
• Make and package proteins and lipids

• Much like an assembly line


• Found in eukaryotic organisms

• Forms an interconnected network of


flattened, membrane-enclosed sacs
or tubes known as cisternae.
• Largest organelle in eukaryotic cell.
• It provides separate chemical
environment which allows for correct
protein folding.

• Two types Rough Endoplasmic


Reticulum Smooth Endoplasmic
Reticulum
PHYSICAL STRUCTURE
The ER is 3-dimensional network of intracellular. It is
formed of three types of element:

Cisternae
• These are flattened , unbranched, sac-like
element.
• They lie in parallel to one another.
• They bear ribosomes on the surface that,
therefore, appears rough.
• It contain glycoproteins named ribophorin-I &
ribophorin-II that bind the ribosomes.
Tubules
• These are irregular branching element which form a
network along with other element.
• These are often free of ribosomes.

Vesicles
• These are oval and rounded ,vacuole like element.
• These are also free of ribosomes.
• All the element of ER freely communicates with one
another, and contain a fluid called endoplasmic matrix,
in the ER lumen.
• These matrix is different from cytoplasmic matrix
outside the ER
MOLECULAR STRUCTURE
The membrane of ER
are composed of two layers
of phospholipid molecules
sandwiched by two layers of
proteins molecules like
other membrane in the cell
wall.

TYPES
• The endoplasmic reticulum is
of two types:
1-Smooth endoplasmic reticulum
2-Rough endoplasmic reticulum
FUNCTION OF ROUGH ER
• Surface for Ribosomes- The RER
provides space and ribophorins for the
attachment of ribosomes to itself.

• Surface for protein synthesis

• Formation of Glycoprotein- Linking of


sugars to for glycoprotein starts in the
RER and is completed in Golgi complex.

• Synthesis of precursors- The RER


produce enzyme precursors for the
formation of lysosomes by Golgi
Complex.

• Smooth ER formation- The RER gives


rise to the smooth ER by loss of
ribosomes.
FUNCTION OF SMOOTH ER
• The smooth endoplasmic
reticulum lacks ribosomes and
functions in lipid metabolism,
carbohydrate metabolism, and
detoxification and is especially
abundant in mammalian liver and
gonad cells.

• It also synthesizes
phospholipids. Cells which secrete
these products, such as those in
the testes, ovaries, and skin oil
glands have a great deal of
smooth endoplasmic reticulum.
REFERENCES
• https://sites.google.com/site/sharrettsbraincells
/animal-cell/smooth-endoplasmic-reticulum
• https://slideplayer.com/slide/5815399/
• https://biologydictionary.net/endoplasmic-
reticulum/
• https://sites.google.com/site/sharrettsbraincells
/animal-cell/smooth-endoplasmic-reticulum
• https://www.britannica.com/science/rough-
endoplasmic-reticulum
DIOS
MABALOS!

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