Pattern Matching - ANSWER KEY

Download as docx, pdf, or txt
Download as docx, pdf, or txt
You are on page 1of 8
At a glance
Powered by AI
The document discusses classifying organic molecules into lipids, nucleic acids, proteins, and carbohydrates based on their components. It also examines the structures and roles of specific biomolecules like amino acids, nucleotides, and phospholipids.

The four major classes are lipids, nucleic acids, proteins, and carbohydrates. Lipids contain fatty acids and glycerol. Nucleic acids contain nitrogenous bases, pentose sugars, and phosphates. Proteins contain amino acids. Carbohydrates contain carbon, hydrogen, and oxygen.

The monomers of proteins are amino acids, and the monomers of nucleic acids are nucleotides, which contain a nitrogenous base, pentose sugar, and phosphate groups.

Name Date Per

AP Biology / Rodgers

Pattern Matching: Classifying Organic Molecules

Background: You have previously learned about the four classes of large biological molecules: lipids,
nucleic acids, proteins, and carbohydrates. In this activity, you will work with a group to identify the
major classes of organic molecules and distinguish the features of each class of molecules. There may be
as many as 10,000 different kinds of molecules in a living thing. In this activity you will examine,
distinguish the features of, and classify 45 different molecules.

Which elements are present in each type of molecule? Start by filling in the table, writing “Always,”
“Sometimes,” or “Never” in each box.

Carbon Hydrogen Nitrogen Oxygen Phosphorus Sulfur


Proteins Always Always Always Always Never Sometimes
Carbohydrates Always Always Never Always Never Never
Nucleic Acids Always Always Always Always Always Never
Lipids Always Always Never Always Never Never

With your chart complete, begin your work by removing your cards from the bag. Count them to ensure
that you have all 45. You will notice that the cards are numbered; these are their identifiers: you will use
them to answer the questions in this activity. You do not need to put them in number order.

After you have ensured you have a complete set of cards, work together to put the cards into FIVE
stacks: Proteins, Carbohydrates, Nucleic Acids, Lipids, and Unknown. Use the chart above to help you
sort your molecules. Remember, work as a group does not mean “divide and conquer” where each
student does a handful. Work as a group means you discuss the features of each card and determine
together where it should belong.

Once all the cards have been sorted, describe the patterns, shapes, and/or function groups you noticed
that led you to sort the cards as you did.

Things we noticed…

Proteins

Carbohydrates

Nucleic Acids

Lipids
Look more closely at the stack of “Unknowns” – Can you group those into smaller groups? Do any have
similar structures? Describe the features of the unknowns that seem to be patterns among two or more
of the cards in your unknown. For example, “Card X and Y both have…”

Check in with your teacher before you move on.

PROTEINS
Proteins are molecules that play many important roles in the body, including muscle structure,
hormones, antibodies to neutralize pathogens, hemoglobin for carrying oxygen, transport proteins for
moving molecules across cell membranes, chemical messengers in the nervous system, and many, many
more. What is the monomer of a protein called?

Amino Acid

Figure 1 shows a “generic” amino acid, or one that doesn’t have a side
chain, or “R group.” Two amino acids are joined by dehydration
synthesis reactions to form a dipeptide; when three or more amino acids
are joined they are referred to as a polypeptide. Once a polypeptide has
folded into a functional conformation (shape) it is referred to as a
protein. When amino acids are joined together, the “-N-C-C-“ in the
center of the molecule is known as its backbone and is a defining feature
of amino acids. A typical protein chain may contain 150 – 1000 or more amino acids. There are 20
common amino acids that are used to build protein molecules. Cells string amino acids together end-to-
end as shown in Figure 2.
Each amino acid has a different side group that is represented by “R” in Figures 1 and 2. Two amino
acids with their particular side groups are shown in Figure 3.

Focusing only on the cards you placed in “Proteins,” lay out all of the amino acids. How many did you
originally identify? You should have 14. If you don’t have all 14 amino acids, sort through your other
piles, beginning with “Unknown” until you find all 14 amino acids. List the cards numbers here of your
amino acids:

2 6 9 13 15 16 18

20 21 24 25 26 27 28

We will now look more closely at these 14 amino acids. Bearing in mind that the properties of the R-
group determine the behavior of the amino acid, separate the amino acids into two stacks: polar and
non-polar. Hint: A highly electronegative atom on the end of an R-group will cause the amino acid to be
polar and a series of hydrocarbons on the end of an R-group will cause the amino acid to be nonpolar.

You should find 6 non-polar amino acids. List the cards here of the non-polar amino acids:

2 6 13 20 21 25

Are these amino acids more likely to be found on the interior or exterior of a globular protein that exists
in the cytosol of a cell?

Interior, away from the aqueous cytosol.

You should find 8 polar amino acids. List the cards here of the polar amino acids:

9 15 16 18 24 26 27 28

Are these amino acids more likely to be found on the interior or exterior of a globular protein that exists
in the cytosol of a cell?

Exterior, in contact with the aqueous cytosol.

Looking even more closely at the polar amino acids, you should find three that have a charged R-group.
List the cards here of the charged amino acids:

15 16 18

Last, find the ONE amino acid that has a terminal (end) sulfur atom that could engage in a “di-sulfide
bridge.” What’s its card number?

Card 26
CARBOHYDRATES
Carbohydrates are also versatile molecules that store energy and provide structure to
organisms. You may have heard of simple carbohydrates, sugar, or complex carbohydrates,
such a fiber. Sugars occur as ring structures. There are monosaccharides (single rings),
disaccharides (double rings), and larger structures called polysaccharides. In solution, single
rings can dynamically change from straight chains to rings and back to straight chains. A
straight chain sugar is shown below. Notice that ever carbon has an oxygen atom attached to
it.

Sugars can be joined together in long chains to form macromolecules called starch, cellulose,
and glycogen. A plant’s starch and an animal’s glycogen are easily broken down into sugars for
energy. Cellulose, on the other hand, which is made primarily in plants, can be broken down
only by a few organisms in the world – primarily the bacteria in the guts of termites. Yet all
three types of macromolecules are made of long chains of monosaccharides, and cellulose
differs only by a small change in the connecting bond between each pair of sugars.
Pick up your pile of carbohydrate cards. You should have 11 of them. If you don’t, sort through
your pile of unknowns to search for more. Remember, carbohydrates only contain carbon,
oxygen, and hydrogen in a very specific 1 carbon:2 hydrogen:1 oxygen ratio.
List the card numbers for the 11 carbohydrate molecules:
1 3 5 10 12 14 17 22 23 29 34
Further divide your set of 11 cards into monosaccharides, disaccharides, and polysaccharides.
Which cards are straight chain monosaccharides?
1 5 12 14 17 22
Which cards are ring monosaccharides?
3 29
Which cards are disaccharides?
10 23
Which card is a polysaccharide?
34
Look again at your two disaccharides. One of them is common table sugar. Look up “sucrose”
in your book or online. Which two monosaccharides combine to form sucrose? Draw them
below. Which atoms are removed during the bonding of the two monosaccharides?
Glucose and Fructose

Lipids
Lipids are a diverse group of molecules that share one important trait: they are hydrophobic.
Lipids are most easily recognized by having lots of hydrocarbons, which contain non-polar
covalent bonds. Lipids may have a few polar bonds associated with oxygen, depending on the
specific molecule, but on the whole lipids consist mostly of hydrocarbons.
Lipids vary widely in both form and function and include things like waxes and pigments. In this
activity we’ll focus on fats, phospholipids, and steroids.
First, ensure you have all of the lipid cards – there are 8 of them. Look for molecules that have
long chains or rings of hydrocarbons. List the lipids here:
33 35 36 37 38 40 42 44

Steroids
Steroids are one type of molecule in the class of compounds known
as lipids. Cholesterol, shown at the right, is a steroid, and plays an
important role in membrane formation. Steroids can be recognized
by their multiple rings of carbon atoms connected together.
Find the 3 steroids in your stack of cards. Identify them here:
40 42 44
It’s useful to keep in mind that, similar to proteins, molecules can have regions that are
nonpolar and regions that are polar. This is incredibly important in cell membrane functions.
Re-examine the cholesterol molecule. Circle the region of the molecule that is polar.
Fats and Fatty Acids
Among your cards you should have some long hydrocarbon chains with a carboxyl group at one
end. One of the defining features of these hydrocarbon chains is the absence of oxygen except
in one carboxyl group at one end of the molecule.
Draw a carboxyl group here:
Is a carboxyl group polar or non-polar? The presence of which element tells you this?
Polar. Oxygen.
Fatty acids can exist alone as a single chain of hydrocarbons, or can join a glycerol
molecule to form larger molecules with multiple chains. The chains themselves can
vary in terms of the presence or absence of double bonds between the carbon
molecules. Fatty acids that contain no double bonds are considered saturated. Fatty
acids that contain at least one double bond are considered unsaturated. Saturated
fats are solid at room temperature because the chains pack together more densely
than do unsaturated fats, which are liquid at room temperature and less dense.
Saturated fats tend to be found in land animals; unsaturated fats tend to be found in plants and
fish.
Identify the three cards that show individual fatty acid chains.
33 35 36
Look more closely at these three cards. Which chains are saturated? How can you tell?
33 35 There are no double bonds.
Which chain is unsaturated? How can you tell?
36 There are double bonds present.
You should now have two larger molecules remaining, each with multiple fatty acid chains
attached to a glycerol. Fats, as you consume them in your food, are formed by joining three
fatty acids to a glycerol molecule. In addition to the number of double bonds, the length of the
fatty acid chains can also vary. Which card shows a molecule that is a fat?
38.
This fat is known as a triacylglycerol, or a triglyceride. This is one of the molecules that is found
in your blood. Doctors track the amount of triglycerides found in blood. Too much triglyceride
in your blood is a possible indicator of heart disease.
The last remaining lipid is a phospholipid. Look closely to see that there are two fatty acid
chains attached to a glycerol. The third carbon on the glycerol molecule has a phosphate
attached to it.
Which card is the phospholipid?
37
Is a phosphate group polar or nonpolar?
Polar
Are the fatty acid chains polar or nonpolar?
Nonpolar
This molecule is “amphipathic,” meaning that is has both hydrophilic and hydrophobic regions.
On this simplified diagram of a phospholipid, label the polar region and the nonpolar region of
the molecule.

Phospholipids are essential for cells because they are major constituents
of cell membranes. In this diagram of a cross-section of a cell membrane, label the region that
is nonpolar and the two regions that are polar.

Nucleic Acids
Nucleic Acids store, transmit, and help express hereditary information. You should have 12
cards remaining. The monomer of nucleic acids are nucleotides, which themselves contain a
nitrogenous base, a sugar, and anywhere from 1 to 3 phosphate groups. Five of your cards
contain only the nitrogenous bases: a single or double-ring structure that contains nitrogen.
Identify the five nitrogenous bases. Ensure the cards you select do not
contain a pentose sugars, as shown here:
Which cards contain nitrogenous bases?
4 7 8 11 19
Nitrogenous bases are either pyrimidines (single ring structures) or purines (double ring
structures). Which of the five cards are pyrimidines?
8 11 19
Which of the five cards are purines?
4 7
The nitrogenous base connects directly to a pentose sugar, either ribose in RNA or deoxyribose
in DNA. In the diagram above, circle the Oxygen that is present on ribose that is absent on
deoxyribose. You have four cards that show a nitrogenous base attached to a pentose sugar.
When molecules are in this state, they care called nucleosides. Which cards are these?
39 41 43 45
Look closely at the sugars on each card. Do these molecules contain ribose or deoxyribose?
Ribose
When nucleosides combine with one, two, or three phosphates they are then nucleotides. The
more phosphates that are present, the more energy contained in the molecule. Adenosine
triphosphate (ATP) is not only a major subunit of DNA and RNA, but also a major energy carrier
in living systems. How many phosphate groups should you expect to find in adenosine
triphosphate?
3
Which of your cards contains ATP?
32
When ATP is used for cellular energy, water hydrolyzes the terminal phosphate group from the
ATP, leaving only two phosphates behind – a molecule called adenosine diphosphate. Which of
your cards contains ADP?
31
Through a process called cellular respiration, glucose is broken down and the terminal
phosphates that were removed are added back on to ADP, so these molecules are continuously
recycled by the cell. While nucleotides that are free floating in the cell’s cytoplasm typically
consist of three phosphate groups, when each is added to a growing molecule of DNA or RNA,
the end two phosphate groups are removed by dehydration synthesis, leaving only one
phosphate group. Which of your cards contains a molecule that looks like this?
30
On the molecule of a different nucleotide to the right, label the phosphate,
pentose, and nitrogenous base. The single pentose sugar and the single
phosphate group on each nucleotide join with others so as to form a sugar-
phosphate backbone of a molecule, with the nitrogenous bases on the interior
of the molecule. Now examine the molecule below.

Which letter represents the phosphate group? Z


Which letter represents the pentose sugar? Y
Which letter represents a purine? W
Which letter represents a pyrimidine? X

You might also like

pFad - Phonifier reborn

Pfad - The Proxy pFad of © 2024 Garber Painting. All rights reserved.

Note: This service is not intended for secure transactions such as banking, social media, email, or purchasing. Use at your own risk. We assume no liability whatsoever for broken pages.


Alternative Proxies:

Alternative Proxy

pFad Proxy

pFad v3 Proxy

pFad v4 Proxy