This Topic. So Congratulations Because Today I'm Going To Talk About The
This Topic. So Congratulations Because Today I'm Going To Talk About The
Greeting everyone! your lecturer for the this topic. So congratulations because today I’m going to
talk about the main event the big bonanza the super bowl of cellular respiration, which are The Electron
transport chain and the Chemiosmosis
Slide 2: This is what we had discussed so far, glucose can undergo glycolysis to become pyruvate. Pyruvate
can also go back up to glucose through gluconeogenesis. Pyruvate can take one of four metabolic pathways.
However, the most common destination for pyruvate is to be turned back into acetyl coA. A cetyl coA can
then go through the TCA cycle also known as the krebs cycle to generate NADH AND FADH2.
So this NADH AND FADH2 are incredibly important. Why? Because this two byproduct are the key to move on
to the next processes which are ETC and chemiosmosis.
READ SLIDE 4
READ SLIDE 5
SLIDE 7
READ SLIDE 7
As I mentioned earlier ETC is composed of this I-IV complex then Chemiosmosis is composed of ATP
Synthase.
Video Script:
All of the steps of aerobic respiration that we have done so far have been leading up to this the electron
transport chain & Chemiosmosis.
As I said earlier this is the main event of the cellular respiration. Why?
In the animation, you can see the electron transport chain as series of proteins and other transport molecules
are embedded in the inner membrane of the mitochondrion.
NADH, that electron carrier we've been making all along delivers its electrons to the Protein complex I as the
electrons move through this protein complex, energy is gradually released, and this energy is used to pump
hydrogen ions or protons across from the matrix into the inter-membrane space.
you might realize that moving electrons is electricity. basically these electrons can
At this point,
provide the energy to drive these microscopic pumps made out of protein.
They are basically natural electric pumps found inside our body,
Next
The electrons are then transported by the special red molecule called (ubiquinone or Q) toward
their next destination, the ubiquinone also picks up the electrons in complex II donated by
FADH2, that was also made during the Krebs cycle.
Now, the electrons are transported by molecule cyt c to final protein complex IV, where their
energy is used, Once again to pump hydrogen ions into the inter membrane space, making the
concentration even higher.
Now the electrons need somewhere to go a final destination to complete their journey.
(oxygen appears) Fortunately you breathe, and oxygen comes to the rescue
Oxygen accepts the electrons as well as hydrogen from the matrix making water.
This is the reason why you breathe all day every day,
your cells need oxygen to accept these electrons or the electron transport chain will grind to a
halt, like EDSA during rush hour,
and if the electron transport chain stops, you won't be able to make enough ATP to keep you
alive and you die.
now you may have noticed that we haven't made atp yet. So you might be wondering how
that works?
which brings up the coolest part of this entire process
You may remember that molecules tend to move from areas of high concentration to low
concentration naturally
a process known as DIFFUSION.
So, these hydrogen ions in a manner of speaking want to flow from the high concentration area
of the inter membrane space to the low concentration area the matrix,
But!! they can only get through ATP SYNTHASE,
this facilitated diffusion of hydrogen ions through atp synthase causes atp synthase to spin like a
turbine and produce ATP
It's like a microscopic hydroelectric dam generating atp instead of electricity as hydrogen ions,
passively flow through
since we made many electron carriers throughout respiration, the electron transport chain
happens over and over again,
making between 30 to 34 atp molecules for every glucose that entered respiration.