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    Drug Name Mode of Action Indications Side Effects Nursing Interventions Generic Name

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    dodong skyrose
    Generic name: Eplerenone Indications: Hypertension (alone or with other agents), LV systolic dysfunction and evidence of HF post-MI. Contraindications: Serum potassium >5.5 mEq/L, serum creatinine >2 mg/dL in males or >1.8 mg/dL in females, concurrent use of strong CYP3A4 inhibitors or potassium supplements. Side effects: Dizziness, fatigue, abdominal pain, diarrhea, albuminuria, abnormal vaginal bleeding, gynecomastia, hyperkalemia.

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    Drug Name Mode of Action Indications Side Effects Nursing Interventions Generic Name

    Uploaded by

    dodong skyrose
    148 views6 pages
    Generic name: Eplerenone Indications: Hypertension (alone or with other agents), LV systolic dysfunction and evidence of HF post-MI. Contraindications: Serum potassium >5.5 mEq/L, serum creatinine >2 mg/dL in males or >1.8 mg/dL in females, concurrent use of strong CYP3A4 inhibitors or potassium supplements. Side effects: Dizziness, fatigue, abdominal pain, diarrhea, albuminuria, abnormal vaginal bleeding, gynecomastia, hyperkalemia.

    Original Description:

    drug study

    Original Title

    aldactone

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    Generic name: Eplerenone Indications: Hypertension (alone or with other agents), LV systolic dysfunction and evidence of HF post-MI. Contraindications: Serum potassium >5.5 mEq/L, serum creatinine >2 mg/dL in males or >1.8 mg/dL in females, concurrent use of strong CYP3A4 inhibitors or potassium supplements. Side effects: Dizziness, fatigue, abdominal pain, diarrhea, albuminuria, abnormal vaginal bleeding, gynecomastia, hyperkalemia.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    148 views6 pages

    Drug Name Mode of Action Indications Side Effects Nursing Interventions Generic Name

    Uploaded by

    dodong skyrose
    Generic name: Eplerenone Indications: Hypertension (alone or with other agents), LV systolic dysfunction and evidence of HF post-MI. Contraindications: Serum potassium >5.5 mEq/L, serum creatinine >2 mg/dL in males or >1.8 mg/dL in females, concurrent use of strong CYP3A4 inhibitors or potassium supplements. Side effects: Dizziness, fatigue, abdominal pain, diarrhea, albuminuria, abnormal vaginal bleeding, gynecomastia, hyperkalemia.

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    © All Rights Reserved
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    of 6

    DRUG NAME MODE OF INDICATIONS CONTRAINDICATI SIDE EFFECTS NURSING

    ACTION ONS INTERVENTIONS


    Generic Blocks the hypertension : Serum potassium CNS: Dizziness,
    ● Monitor BP
    name : effects of (alone, or with 5.5 mEq/ L; Type 2 fatigue
    periodically
    Eplerenone aldosterone other agents). LV diabetes with GI: abdominal liver
    during therapy.
    by attaching systolic microalbuminuria function tests,
    ● Monitor
    to dysfunction and (for patients with abdominal pain,
    prescription
    mineralocorti evidence of HF HTN;qrisk of diarrhea. GU:
    refills to
    Brand name : coid post-MI hyperkalemia); albuminuria. Endo:
    determine
    Inspra receptors. Serum creatinine 2 abnormal vaginal
    adherence.
    Therapeutic mg/dL in males or bleeding,
    ● Instruct patient
    Effects: 1.8 mg/dL in gynecomastia.
    to take
    Therapeutic Lowering of females (for F and E:
    medication as
    class: BP. patients with HTN); HYPERKALEMIA.
    directed at the
    Antihypertensiv Improves CCr 30 mL/min (for Metab:
    same time each
    es survival in all patients); CCr hypercholesterolemi
    day, even if
    patients with 50 mL/min (for a,
    feeling well. ●
    Pharmacologic evidence of patients with HTN); hypertriglyceridemia
    Encourage
    class : HF post-MI Concurrent use of . Misc: flu-like
    patient to comply
    Aldosterone potassium symptoms
    with additional
    antagonist supplements or
    interventions for
    potassium-sparing
    hypertension
    diuretics (for
    (weight
    patients with HTN);
    reduction,
    Actual dose , Concurrent use of
    discontinuation
    Timing : strong inhibitors of
    of smoking,
    50 mg twice the CYP3A4
    moderation of
    daily, PO enzyme system
    alcohol
    (ketoconazole,
    consumption,
    itraconazole,
    regular exercise,
    nefazodone,
    stress
    clarithromycin,
    management).
    ritonavir, or
    Medication
    nelfinavir)
    controls, but
    does not cure,
    hypertension. ●
    Instruct patient
    and family on
    correct
    technique for
    monitoring BP.
    Advise them to
    monitor BP at
    least weekly,
    and notify health
    care
    professional of
    significant
    changes.
    ● Inform patient
    not to use
    potassium
    supplements,
    salt substitutes
    containing
    potassium, or
    other Rx, OTC,
    or herbal
    products without
    consulting health
    care
    professional.
    ● May cause
    dizziness.
    Caution patient
    to avoid driving
    or other activities
    requiring
    alertness until
    response to
    medication is
    known.
    Advise patient to
    notify health
    care
    professional if
    dizziness,
    diarrhea,
    vomiting, rapid
    or irregular
    heartbeat, lower
    extremity
    edema, or
    difficulty
    breathing occur.
    ● Advise patient
    to inform health
    care
    professional of
    treatment
    regimen prior to
    treatment or
    surgery.
    ● Advise patient
    to notify health
    care
    professional if
    pregnancy is
    planned or
    suspected.
    Advise patient to
    avoid breast
    feeding during
    therapy.
    ● Emphasize the
    importance of
    follow-up exams
    to check serum
    potassium.

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