DNA Vs RNA

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DNA RNA

The main job of RNA is to


transfer the genetic code need
for the creation of proteins
from the nucleus to the
Medium of long-term storage ribosome. this process
Job/Role: and transmission of genetic prevents the DNA from
information having to leave the nucleus,
so it stays safe. Without
RNA, proteins could never be
made.

Stands for: DeoxyriboNucleicAcid RiboNucleicAcid

A single-stranded molecule in
Typically a double- stranded
most of its biological roles
Predominant Structure: molecule with a long chain of
and has a shorter chain of
nucleotides
nucleotides

A-T(Adenine-Thymine), G- A-U(Adenine-Uracil), G-
Pairing of Bases:
C(Guanine-Cytosine) C(Guanine-Cytosine)

Deoxyribose sugar in DNA is Ribose sugar is more reactive


less reactive because of C-H because of C-OH (hydroxyl)
bonds. Stable in alkaline bonds. Not stable in alkaline
Stability: conditions. DNA has smaller conditions. RNA on the other
grooves where the damaging hand has larger grooves
enzyme can attach which which makes it easier to be
makes it harder for the enzyme attacked by enzymes.
to attack DNA.

The helix geometry of DNA is The helix geometry of RNA


of B-Form. DNA is completely is of A-Form. RNA strands
protected by the body i.e. the are continually made, broken
Unique Features:
body destroys enzymes that down and reused. RNA is
cleave DNA. DNA can be more resistant to damage by
damaged by exposure to Ultra- Ultra-violet rays.
violet rays

1.Found in nucleus and


1.Found in nucleus
cytoplasm
Difference: 2. sugar is deoxyribose
2.sugar is ribose.
3. Bases are A,T,C,G
3. Bases are A,U,C,G
DNA RNA
DNA is a long polymer with a RNA is a polymer with a
deoxyribose and phosphate ribose and phosphate
Bases & Sugars: backbone and four different backbone and four different
bases: adenine, guanine, bases: adenine, guanine,
cytosine and thymine cytosine, and uracil

RNA, single-stranded chain


of alternating phosphate and
ribose units with the bases
A nucleic acid that contains the adenine, guanine, cytosine,
genetic instructions used in the and uracil bonded to the
Definition:
development and functioning ribose. RNA molecules are
of all known living organisms involved in protein synthesis
and sometimes in the
transmission of genetic
information.

The main difference between DNA and RNA is the sugar present in the molecules. While the sugar

present in a RNA molecule is ribose, the sugar present in a molecule of DNA is deoxyribose.

Deoxyribose is the same as ribose, except that the former has one more OH.

DNA does not usually exist as a single molecule, but instead as a tightly-associated pair of molecules.

These two long strands entwine like vines, in the shape of a double helix. This arrangement of DNA

strands is called antiparallel. The asymmetric ends of DNA strands are referred to as the 5′ (five

prime) and 3′ (three prime) ends. One of the major differences between DNA and RNA is the sugar,

with 2-deoxyribose being replaced by the alternative pentose sugar ribose in RNA. The four bases

found in DNA are adenine (abbreviated A), cytosine (C), guanine (G) and thymine (T). A fifth

pyrimidine base, called uracil (U), usually takes the place of thymine in RNA and differs from thymine

by lacking a methyl group on its ring.

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