This document summarizes various urine preservatives, their advantages, disadvantages, and additional information. Common preservatives include refrigeration, thymol, boric acid, formalin, toluene, sodium fluoride, phenol, and commercial preservative tablets. Urine collection kits from companies like Becton Dickinson contain collection cups and tubes with preservatives like boric acid or sodium propionate to preserve samples for chemical testing, cultures, and automated instrument analysis while minimizing interference.
This document summarizes various urine preservatives, their advantages, disadvantages, and additional information. Common preservatives include refrigeration, thymol, boric acid, formalin, toluene, sodium fluoride, phenol, and commercial preservative tablets. Urine collection kits from companies like Becton Dickinson contain collection cups and tubes with preservatives like boric acid or sodium propionate to preserve samples for chemical testing, cultures, and automated instrument analysis while minimizing interference.
This document summarizes various urine preservatives, their advantages, disadvantages, and additional information. Common preservatives include refrigeration, thymol, boric acid, formalin, toluene, sodium fluoride, phenol, and commercial preservative tablets. Urine collection kits from companies like Becton Dickinson contain collection cups and tubes with preservatives like boric acid or sodium propionate to preserve samples for chemical testing, cultures, and automated instrument analysis while minimizing interference.
This document summarizes various urine preservatives, their advantages, disadvantages, and additional information. Common preservatives include refrigeration, thymol, boric acid, formalin, toluene, sodium fluoride, phenol, and commercial preservative tablets. Urine collection kits from companies like Becton Dickinson contain collection cups and tubes with preservatives like boric acid or sodium propionate to preserve samples for chemical testing, cultures, and automated instrument analysis while minimizing interference.
Preservatives Advantages Disadvantages Additional Information
Refrigeration - Does not interfere with chemical - Raises specific gravity by - Prevents bacterial growth 24 h tests hydrometer - Precipitates amorphous phosphates and urates Thymol - Preserves glucose and sediments - Interferes with acid precipitation well tests for protein Boric acid - Preserves protein and formed - May precipitate crystals when used - Keeps pH at about 6.0 elements well in large amounts - Does not interfere with routine - Is bacteriostatic (not bactericidal) at analyses other than pH 18 g/L; can use for culture transport - Interferes with drug and hormone analyses Formalin (formaldehyde) - Excellent sediment preservative - Acts as a reducing agent, - Rinse specimen container with interfering with chemical tests for formalin to preserve cells and casts glucose, blood, leukocyte esterase, and copper reduction Toluene - Does not interfere with routine tests - Floats on surface of specimens and clings to pipettes and testing materials Sodium fluoride - Prevents glycolysis - Inhibits reagent strip tests for - May use sodium benzoate instead - Is a good preservative for drug glucose, blood, and leukocytes of fluoride for reagent strip testing analyses Phenol - Does not interfere with routine tests - Causes an odor change - Use 1 drop per ounce of specimen Commercial preservative - Convenient when refrigeration not - May contain one or more of the - Check tablet composition to tablets possible preservatives including sodium determine possible effects on - Have controlled concentration to fluoride desired tests minimize interference Urine Collection Kits (Becton - Contains collection cup, C&S Dickinson, Rutherford, NJ) preservative tube or UA tube Gray C&S tube - Sample stable at room temperature - Decreases pH; do not use if urine is - Preservative is boric acid and may (RT) for 48 hr; preserves bacteria below minimum fill line not be used for UA Yellow plain UA tube - Use on automated instruments - Must refrigerate within 2 hours - Round or conical bottom Cherry red/yellow top tube - Stable for 72 hours at RT; - Bilirubin and urobilinogen may be - Preservative is sodium propionate; instrument-compatible decreased if specimen is exposed to conical bottom light and left at RT Saccomanno Fixative - Preserves cellular elements - Used for cytology studies