The Phoenix Protocol - Dry Fasting by A Dunning

Dry
Rapid Healing
and
Radical Life Extension
August Dunning
The fhoenix f rotocol
The Fhoenix Frotocol

Dry Fasting
For
Rapid Healing
And
Radical Life Extension
August Dunning
2Dd Edition - May 2020
The Fhoenix F rotocol The Fhoenix F rotocol
This book contains the opinions and ideas of its author. It is intended to provide
helpful and infonnative infonnation on the subject discussed herein. It is sold
with the understanding that the author is not engaged in rendering medical,
health or any other kind of professional services.
This book contains advice and infonnation related to health care. It should be
used to supplement rather than replace the advice of your doctor or another
trained health professional. The reader should always consult his or her health
care provider to detennine the appropriateness of the infonnation for his or her
own situation or if be or she has any questions regarding a medical condition or
treatment plan, (t is recommended that you seek your physician's advice before
embarking on any medical program or treatment.
This book is dedicated to Sergei and Leonid,

without whom this book would not be possible.
AJI efforts have been made to assure the accuracy of the infonnation contained
in this book. The author disclaims any liability for any medical outcomes that
may occur as a result of applying the methods suggested in this book.
No part of th is publication may be reproduced or distributed in any fonn or by

any means, electronic or mechanical, or stored in a database or retrieval system,
without the prior written permission of the author.
THE PHOENIX PROTOCOL Copyright IC 2020 August Dunning

All rights reserved
ii iii
The Fhoenix Frotocol The Fhoenix Frotocol
Contents
INTRODUCTION [Aii"Outrageous Idea
DRY FASTING FOR R

...A..P.IDH
. E.A.l.IN.G _ __
[ 1 - Beneficial Stress 5
2 - Dry Fasting 9
3 - Water Fasting 21
4 - Autophagy - Cellular Housekeeping 27
5 - Sirtuins and Viral Infection 37
'===
, 6 - The Doctors Who Perfected Dry Fasting Yl
DRY FASTING FOR RADICAL LIFE EXTENSION
~We Can Win a Losing Battle
8 - Aging and Age Reversal 81
9 - Restoring Youth 91
Lver.':Jone has a d octor in him or her; we just 10 - Endogenous Stem Cell Therapy 95
have to help it in its work. The natural healing 11 - Telomerase Activity in Stem Cells 105
force within each one of us is the greatest 1 12 - Muse AT Stem Cells
force in getting well. 13 - The Phoenix Protocol 113
E>ut to eat when .':Jou are sick, 14 - Feeding New Stem Cells 127
is to feed .':Jour sickness.
EPILOGUE I No Expiration Date
Hippocrates at Kos
RECOMMENDATIONS 133
REFERENCES 136
GLOSSARY 14S
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An Outrageous Idea
"We are all agreed that your theory is crazy.
The question which divides us is whether
it's crazy enough to have a chance of being correct. "
- Niels Bohr
Everyone has a list of perfect foods, everyone has the

perfect diet and after millions of pills, potions and
promises we still don't live any longer. In fact, America
spends more on health care than any other nation on
Earth and has more food than any other nation . Isn ' t it
odd that Americans are not the longest living, healthiest
"We cannot discover new oceans
people on Earth? Never do we stop to think that maybe
unless we have the courage to lose sight of the shore."
- Andre Gide
medicine and food is not the answer. Hippocrates
observed in 400BC that illness continues as long as food is
administered. No one ever stops to ask if eating prevents
healing.
This book will explain how, by not eating, we can heal

illness, lengthen lifespan and maybe ... even live forever.
Recent scientific discoveries in cellular and anti-aging
research have produced the data to support this idea.
All the knowledge exists but extending life to live
longer in a body progressively ravaged by age is not an
idea worth pursuing. To this end, I ask you to consider an
idea that is worth pursuing; to have both a longer life and
a younger body by employing a therapeutic healing
method called Dry Fasting.
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Dry fasting is not new, it was a fully developed rapid In this way the Phoenix Protocol can reliably activate
healing therapy in Russia years before it was introduced to repeated sustained rejuvenation periods that no other
the West. Dry fasting has been popularized lately as a restorative methodology can accomplish.
method for rapid weight loss but weight loss is not the
Out with the old, in with the newer and newer you ...
focus of this book. The interest to use dry fasting in this
way was likely lifted from the work of the two Russian In a way you are in a car speeding towards the edge of a
doctors who perfected it; Dr. Leonid A. Shchennikov and cliff. The Phoenix Protocol allows you to stop, put the car
Dr. Sergei I. Filonov. Dry fasting is indeed very effective for in reverse, back up and move away from the cliff. The cliff
weight loss and it's one of its major benefits but not the is always there but you can decide how far away the car is
primary one. from the cliff.
The Phoenix Protocol employs dry fasting for two This book is not a long one, it's not a text book. I will,
unique outcomes; rapid healing and its ability to activate however, strive to clearly explain the rather complex
adult stem cells. Activating adult stem cells is its science in a way to satisfy the curiosity of any reader at
unexpected potential; endogenous stem cell therapy. any level of their understanding of human physiology.
Recent discoveries in anti-aging research regarding
the processes of cellular repair leads me to believe that And although some of the science is quite complex, I'll try
the Phoenix Protocol is a logical way to dramatically to explain it as simply as I can.
extend lifespan in a younger body; one that's backed by
You can certainly use this book to learn how to dry fast
hard science.
I believe, that when properly administered, the correctly to restore health and improve your chances of
Phoenix Protocol can extend lifespan by 25 years or more. living longer, but as you will see this outrageous idea is
about more than dry fasting for health and longevity ...
I'm certain I've found the way to have both a longer life
and a younger body and perhaps even more than that.
. .. it's about functional immortality.
The Phoenix Protocol is an idea; to remove senescent cells
and repeatedly replace them with endogenous stem cell
infusions to ultimately restore youth and radically extend
lifespan.
2 3
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Chapter 1
Beneficial Stress
'That which does not kill us, makes us stronger. "
- Friedrich Nietzsche
Dry fasting is hormetic stress. It's a nutritional challenge to

initiate an adaptive response that improves biological
functionality and thereafter a higher tolerance to more
severe challenges. III
Dry fasting is a self-imposed abstinence from food and

water to cause an adaptive response to make you stronger;
~iIli~::..~'h, 'more ready for what comes next.' Our species is still here
I) :!ft~ r ..!!1i1I:ons of years because we were improved by
stress.
. ...... - .....
~
'"
Stress is the force that, more t han iikely, moved us
forward along the evolutionary ladder. Stress creates
better adaptability in all species. That being said,
notwithstanding the changes from genetic mutation by
"Natural forces within us solar and cosmic radiation during geomagnetic field
are the true healers oj disease." excursions, the present state of biological complexity is
- Hippocrates probably a result of stress, not luck.1107] It's stress that
favors the strong to adapt when environmental conditions
change and force the weak to leave the gene pool.
Adaptation keeps the ball rolling using new genetic
variations to survive the ever-changing environment.
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In nature, plants produce phytochemicals as a hormetic reduced the gene pool to those most able to adapt to
response to the stress of insect attack in order to survive stress. You are the descendant of ancestors that
in their world of insect predators. Plants can't run away responded to starvation stress with the ability to preserve
from predators and have had to adapt to their ever vital body proteins. Humans wouldn't have survived if an
changing environment in a different way. Stress induced alternative energy source other than glucose couldn't be
phytochemicals deter predators. called upon to preserve muscle during starvation stress.
Simply put, many of these plant attack-response Our brain would have been extremely vulnerable during
chemicals are bitter and bugs don't like the taste. So seen starvation if it only relied on glucose. Our muscle tissue
correctly, plant phytochemicals are not synthesized by would have been broken down rapidly and converted into
plants for humans, phytochemicals are a successful glucose to feed our sugar-hungry brains until we didn't
response to stress in order to survive long enough to have enough muscle strength left to find food.
reproduce. It's just a coincidence that some of these
phytochemicals are beneficial to humans, many are not - Fortunately humans developed an ability, as a result of
lectins being the perfect example. surviving starvation stress, one that's turned on during
starvation; it's called autophagy. Autophagy is a life-critical
Our ancient human ancestors had to deal with enormous survival trait. It activates the systems that protect brain
environmental stressors to survive Earths evel:'chahging and' rTiUsc1e.• It also cleans the cells, restores metabolic
environment. They had to endure iet. ages, global droughts, function and proviu'g rt building materials for new cells.
had to chase ai1iiio~:s in iheir bare feet, throw a spear to Activating autophagy deTibe;:"fiel'Yil-;§:k~s-'lr easier" -io
take down game and drag it back to the tribe sometimes survive future challenges. It's a beneficial stress.
miles, even days away. Famine and starvation were more
common than feast and plenty. Natural selection allowed This type of stress will be applied in a way to achieve the
the strong to remain to reproduce and carry the species goals of the Phoenix Protocol - to use the beneficial stress
into the future. of starvation to cause a transformation of your aging body
into a more youthful and earlier version. Starvation stress
Our ancestors also had to preserve muscle during times of induces this repair response that's been incorporated into
starvation to escape and survive in their world of animal our genetics.
predators. Essentially you didn't have to out run the
sabretooth tiger, you just had to outrun the others in the
tribe also being chased by the sabretooth tiger. Nature
6 7
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Chapter 2
Dry Fasting
'7a do nothing is a gaod remedy."
- Hippocrates
Dry fasting is a deliberate pause of digestive function for a

number of days. The Phoenix Protocol is only 7 days.
Compared to other types of fasting, dry fasting is a
remarkably more comfortable form as you will soon learn.
There are two types of dry fasting:
"It's not stress that kills us, it's our reaction to it." A soft dry fast allows you to come into contact with
- Hans Sefye water such as bathing, washing your hands and face
but not swallowing any water.
A hard -6rt fOIst ;equires no contact with any water
whatsoever (this type if. ~~sting is not recommended).
". ----- -- - - , --.-~
Dry fasting is a far rarer form of fasting because people
have been convinced that it's impossible to go without
water for longer than three days. But this assumption is
incorrect because the body has the ability to make its own
water, endogenous water, during the transformation of
fatty acids stored in adipose tissue into ATP.
The Russian doctors, who perfected dry fasting,

determined that the only stipulation is that no water
enters the gastrointestinal tract via the mouth. They found
that drinking water stimulates gastric juices and stops the
9
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The Fhoenix Frotoeol The Fhoenix Frotoeol
transition to endogenous nutrition. Drinking water during When liver glycogen runs out early in a fast, blood
a fast also prevents the blood from becoming sugar levels drop as well as insulin levels.[3! Insulin is used
concentrated which then can't stimulate the to move glucose into cells for energy so another way to
hypothalamus to start endogenous water production as produce energy in cells has to be found. 121
described in the next chapter. Bathing is recommended When insulin levels run low, it creates a stress
and takes advantage of the skin's ability to absorb water in response in p cells of the pancreas that signals a cells to
a type of counter flow into the skin. This method improves secrete glucagon. This stress response sends out glucagon
the ability of the body to flush toxins out of the to temporarily find glycogen in muscles for the liver to
extracellular matrix into the lymphatiC system without convert into glucose. Glucagon also stimulates the
gastrointestinal tract involvement.[29,30j pituitary gland to secrete growth hormone to slow muscle
tissue loss at the same time.[41
There are two cardinal rules that cannot be violated during When glycogen in muscle is exhausted, energy
a fast. These are critical physiological conditions that must requirements are met by cleaving triglycerides, stored in
be maintained. fat cells, for their glycerol and fatty acids. Although
1: Blood glucose levels must be maintained because glycerol and fatty acids can be directly turned into fuel, in
the brain and red blood cells absolutely deM""''''''' "rriaiij p~lls throughout the body, they are not used as
glucose for fuel in order to sta:' alill.!.123,27j energy by brai;-,I:t:!I~~t- ~II.
To meet the energy nei:d~ of your brain, the freed
2.' V.i~fJ.'{)[ate,\')..< ,;,":, t,~e heart and skeletal muscles
glycerol and free fatty acids are converted in the liver into
must be protected to prevent loss of function.ls,lol
glucose and ketones in a process called ketogenesis.
Dry fasting obeys the cardinal rules . Ketogenesis produces acetoacetate which is then
As I mentioned in the section on stress, muscle mass IS converted into two other types of ketone bodies:
designed to be protected by using an alternative energy beta-hydroxybutyrate (BHB) for energy and acetone which
source for glucose to avoid breaking down muscle protein is mostly excreted as waste. When ketones build up in the
but also to protect the brain. Brain, heart and muscle mass blood they make the blood more acidic creating a
is protected during dry fasting by drawing on the energy condition called ketosis.[7,55j
stored in fat cells to maintain blood glucose. Fat cells
Gluconeogenesis
contain triglycerides that are a combination of fatty acids
Gluconeogenesis means 'making new sugar'. Being able to
and glycerol and although fatty acids can't be converted
convert amino acids, fatty acids, glycerol and lactate into
into glucose, glycerol can.[2l
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sugar and ketones are all the safeguards needed to meet Physical evidence of endogenous water production
the glucose needs of the body and brain during fasting. Evidence of this is seen in the urine output during a 7 day
When the body has exhausted all other sources to make dry fast while not drinking any water.
glucose, except proteins, muscle tissue is broken down After glucose is exhausted, urine output increases as
into gluconeogenic and ketogenic amino acids to be the fast continues. The results in the image below show
converted into glucose and ketones. that during the first two days of a dry fast, urine output is
Fortunately, the Phoenix Protocol doesn't break down lower because glycogen in the liver is being used to
muscle protein since it doesn't utilize amino acids to produce glucose for metabolism. Notice that the urine
produce glucose.[4,S,7,12,15] After all glycogen is exhausted output is greater during days 3 to 6 when the body is in
the body turns to stored fat in fat cells for metabolism.[2] ketosis. Also notice the total amount of weight loss - 161bs.
Fatty acids are turned into water 7 Day Dry Fast Urine Output
Water makes up 10% of the contents in fat cells while
Weight loss (Ibs)
triglycerides make up 90%. Fat cells provide fatty acids 0 5 5.5 1.5 3 1
that are transformed into your own water; endogenous '- -~ Measured weight (Ibs)
water. Fatty acids are long chains of carbon bon£!ed to 163.0 .~58.0 152.5 151.0 148.0 147.0
hydrogen atoms fixed to an acetyl g!:..<?.';p'
Fatty acids are processed in ~the mitochondria citric
...... ... I ' . J
' acid cycle inside the 37.2 trillion cells of the body to make
ATP. During the production of ATP the carbon+hydrogen
chains in fatty acids are broken apart.
100 grams of fatty acids are converted into 280 grams
Daysl-2 Days3-6
of C02 and 115 grams of H20 (water) from combining Glycolysis Ketosis
oxygen atoms in the air you breathe with the carbon and
The results seen above make it obvious that this amount
hydrogen atoms broken from the chains in fatty acids.
of urine output cannot possibly occur without a source of
Water is just one of the byproducts of creating ATP in
water from inside the body.
the mitochondria so all 37.2 trillion cells are making plenty
Since endogenic water is created from metabolizing
of water. Endogenous water.
fatty acids, there is no requirement for water to be
ingested nor is there any craving for water during a dry
That's why you're not thirsty on a dry fast.
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The f'hoenix f'rotocol The f'hoenix f'rotocol
fast. I can attest to this; I was not thirsty at all during any ~ oxidation in the inner mitochondria matrix cuts CO.CoA
of my dry fasts. from the chains of fatty acids to make small units of
The way the body accomplishes this remarkable feat is by carbon and hydrogen and acetyl CoA: (CH3.CO.CoA). The
stress responses occurring at the cellular level. chains are broke down in this way to enter the citric acid
cycle which produces water in the ATP electron transport
Dehydration stress creates endogenous water chain in all 37.2 trillion cells of the bodY.161
Not drinking water while fasting flips a chemical switch to
convert fatty acids in fat into water.12} But the critical The engine restarts and you stay aloft. This pathway
moment is at the end of day 2, when blood sugar levels fall makes fuel again, saves muscle mass and makes endogenic
dramatically as glycolysis ends after glycogen in liver and water.
muscle is exhausted .. .you're running out offuel.
However, drinking water during fasting prevents
It's analogous to when you're flying in an airplane and the
endogenic water synthesis because fat cells are not
engine stops. You ' re suddenly in free fall and you have to
find more fuel to restart the engine to stay aloft.. .... - Your , .---.
stimulated
.............. to release glycerol and fatty acids for glucose
,-, ....,.--- , -,- ' and water; tr',t, ~1~t;!r,I l1.ever concentrates. Furthermore,
body has two pathways to find fuel...the foll~·:.tllig is the
this forces the body to use ~luco"t:Vgeir§is to make
pathway dry fasting keeps you flying ... • ,,/'-"
glucose from muscle protein. This violates the second
-'
After day 2 of a ,9ry~~~'lrnlfved solids in the blood cardinal rule; to protect muscle mass,
increlise "'-cfue r to dehydration. This stimulates the
" osmoreceptors in the hypothalamus to activate the Drinking water feeds bacteria, viruses and parasites
posterior part of the pituitary gland to release antidiuretic Every form of life requires water including bacteria, viruses
hormone (ADH). ADH stimulates the adrenal medulla on and parasites. By eliminating external water, during a dry
the kidneys to 'release epinephrine. Epinephrine induces fast, the body is forced to create its own endogenous
lipolysis by activating the enzyme lipase to cleave fatty water. But this ability in human metabolism, that has
acids and glycerol from triglycerides stored in fat cells.IS} evolved from stress and natural selection over millions of
Once freed, glycerol and fatty acids are released into years, is not available to the pathogenic organisms.
the blood stream and travel to hepatocytes in the liver Pathogenic organisms can't make their own water and as
which then starts making fuel again - glucose and a result they are eliminated by day 5 of a dry fast. Drinking
ketones.118} The free fatty acids in the blood stream are water during fasting keeps these organisms alive. One
also delivered to mitochondrion in cells all over the body. caveat is the family of RNA virus as explained in chapter S.
14 15
The fhoeni)( r rotocol
The rhoeni)( r rotocol
The body is a complex protein factory that operates

This is why the Russian doctors considered dry fasting to
optimally when fully hydrated. Water is essential for
be the most effective form of fasting because the body
metabolic homeostasis. When a fast begins, the body is
makes its own water; which they call 'Water of Life.'
burning glycogen in the liver and muscle for energy. Water
A secondary source of endogenous water is the byproduct of that energy production in the
Dry fasting also turns on another process; autophagy. In mitochondria. By the second day of a dry fast, most of this
particular chaperone mediated autophagy (CMA). This water production has been eliminated via the urine and
process breaks down protein sources but not muscle this loss represents water weight of about 31bs per day.
protein. Damaged cellular structures are delivered into This does not represent fat loss ... yet. On the third day of a
cells where CMA targets these weak and damaged cells dry fast, the body runs out of glycogen and starts
and digests their cytoskeleton proteins into amino acids converting fat in fat cells for energy and water. From that
inside Iysosomes. This source of amino acids from proteins, point on the weight that's lost is fat.
in cell structures, are also found in scar tissue, tumors,
cysts, folded proteins, AGE's as well as malfunctioning and During the first 2 days of a dry fast only water weight is
~en~scent cells. These sources 9f ;;,vteihs, creat~dby lost. From day 3 to day l fat is lost. After the fast this
autophagy, "1i1'@"i1ol i.JtI':iz~d fci; energy but rather their water weight loss is rapidly regained. This weight gain is
amino acids are re-purposed for metabolic needs like new the body's method of restoring hydration to tissue to
protein synthesis in order to repair cells. maintain proper protein synthesis.
Additionally, water makes up 60% of the volume in
weak cells and when degraded they provide another Expectations regarding weight loss and weight gain must
source of water that is also added to the overall water in be measured with these aspects of body homeostasis.
the system.
Detoxification during dry fasting
Weight changes during and after fasting The detoxification process, during a dry fast, goes mostly
During a dry fast, significant weight is lost and regained unnoticed because the body is eliminating toxins the way
much to the consternation of those employing dry fasting it was designed.
for weight loss. Dry fasting was originally developed as a The body sequesters toxins in fat cells. During a dry
medical therapeutic application for rapid healing not fast, toxins released from fat cells are processed in the
necessarily weight loss. Weight can be kept off after a dry liver and exit the bowel as a dark orange sludge. The body
fast by restricting foods that contain carbohydrates also stores toxins in the body's cells. The counter flow
(sugars). Carbohydrates spike insulin - insulin builds fat.
17
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The Fhoen;x Frotocol The Fhoen;x Frotocol
absorption of water though the skin, from daily showers, Dry fasting is the safest form of fasting
helps flush toxins, from body cells, into the lymphatic As described earlier, when glucose runs out after the
system and this flow enters the blood stream where it's second day of a dry fast, dehydration stress stimulates
excreted in urine. Urine becomes dark and cloudy as toxins epinephrine to mobilize large quantities of glycerol from
and cellular debris are eliminated. adipose tissue. This provides glycerol for conversion into
But at the end of a fast, the urine is clear and normal glucose for metabolism instead of breaking down skeletal
in a very short amount of time. muscle and acts as a protein 'sparer' to protect vital organ
protein.
The Phoenix Protocol obeys both cardinal rules by
maintaining blood glucose levels and protecting heart and
skeletal muscle by employing fat cells instead of muscle
proteins to synthesize glucose and ketones.
Condusion
The important difference between drinking and not
drinking water during a fast is:
Last Day of a 7 day Dry Fast Three Days Later
-Dry fasting regenerates yaur bady in a healing made with
You don't experience the withdrawal symptoms from enormous health ond longevity benefits. It keeps you oloft
caffeine or the detox reactions with dry fasting that are ond ollows you to lond sofely ofter the fost.
typical with water fasting. Water fasting often begins with
-Wa~er fasting farces the breakdown of vital body mass,
suffering through intense headaches with the advice to
putting your life at risk and any health benefits take far
'push through the pain' to get past the uncomfortable
longer to achieve. It keeps you aloft for a while but you risk
start. a crash landing.
I can confirm th is as well, I've tried water fasting and I
won't do it again. After reading the analysis of water
fasting in the next chapter, I'm pretty sure you won ' t
either.
18 19
The f'hoen;){ f'rotoGOl The f'hoen;){ f'rotoGOl
Chapter 3
Water Fasting
"One of life's greatest challenges is knowing enough
about a subject to think you're right but not
knowing enough about it to know you're wrong."
-Neil deGrosse Tyson
A water fast is not a fast, it's a water diet. The best

evidence of this comes from the Russian doctor who
perfected and patented a method of dry fasting. He
discovered from clinical testing that when any external
water is taken into the body it' s treated as food:
Hlf t!:2 r e is any hunger at all during a dry fast,
"You cannot always control what goes on outside, an enema will stop it."
but you can always control what goeE on iflsirip. " -Dr. Shchennikov
- Wo yne Dyer
Water is a highly deficient form of nutrient in(;::~~ and ,has
mUltiple deleterious effects when consumed while fasting.
Using the airplane analogy in chapter 2, your engine stops,
you are in free fall, but drinking water during a fast diverts
the pathway for fuel down the other pathway. The body
goes into emergency survival mode when it goes down this
pathway and it' s not pretty ...
Energy production during fasting is very different when

you ' re drinking water.[9] The total dissolved solids in the
blood is low and the osmoreceptors in the hypothalamus
are not stimulated to signal the posterior pituitary gland to
release ADH . You have plenty of water. Without ADH the
adrenal medulla isn't stimulated to release epinephrine to
20 21
stimulate Iipolysis.ls,6,U] Without epinephrine, lipase isn't Forearm net protein breakdown increases after 30 and 60
activated to unlock glycerol and fatty acids stored in fat. hours. IIs,I7) When fat is not available for fuel, the effects
This severely reduces the utilization of stored fat for fuel. of growth hormone on protein metabolism become more
When there's no signal to stimulate epinephrine to dig pronounced. Then, instead of protecting muscle mass loss,
into fat stores (since you're fully hydrated) glucose is then growth hormone is used for finding fuel. This results in the
temporarily produced from glycogen stored in skeletal loss of vital body mass protein as urea production rates
muscle.[7,16,21,23] Thereafter, with glycogen exhausted increase by approximately 50%.(10)
and glycerol mostly unavailable from fat cells, hepatocytes But loss of muscle mass is not nearly as important as
in the liver start synthesizing glucose through the loss of vital body mass.
gluconeogenesis using pyruvate, lactate and glucogenic Tohilloss of VltOlIBody Moss jibs)
amino acids (primarily alanine) taken from skeletal muscle 'I ,.
tissue.[14,16,lB) The ketogenic amino acid leucine is used to
make ketones in the absence of fatty acids from fat
celis.[7,12,lS,17,19) Urinary nitrogen excretion has been
"
.~ .. -
reported to be either unchan!:::,1 "r increasing indicating
protein decomp()~!t:8r, because nitrogen is found in amino
aciqs:.!1~·;i2,i3lAmino acids make protein. This is evidenced
- by the loss of skeletal muscle protein, at the beginning of a
fast, when drinking water.[B) The loss rate is reduced over • •1111111
I • .. • • , • • 10 " I'
Pwr....... a.~~
It lot, U .0 ,. i'4 II
1
III n
time but it's only a means of surviving starvation. Vital Body Mass Lost During Water Fastln,· Brown: 2018
oallV LOIS of St.ructul1ll Protaln (araml)
This chart shows cumulative vital body mass lost over the
same period of time as the previous chart. What this chart
-., actually reveals is the indiscriminate digestion of not only

muscle but other protein taken from body organs.[16] The
basic building blocks of vital body mass come from vital
.
rlIIlHIIHfIi'
organ tissue. The most important and vital organ in the
body is the heart and it's being damaged.117) The skeletal
, I • • • • • • d ~ I. " U ~ Il ~ " ~ •• ~ II
muscle mass loss decrease is negated by the total vital
~ .. .,.t.. ~
body mass loss increase. There is no way to avoid this life
Muscle Mass Lost During Water Fasting - Brown: 2018
22 23
The Fhoenix F rotocol The Fhoenix Frotocol
threatening loss of tissue caused by drinking water during link between SIRT2 and fatty acid oxidation has been
a fast. elusive because hydration status has not yet been
considered in research.
Water and the role of sirtuins in gluconeogenesis SIRT3, SIRT4, and SIRTS are primarily located in
There are 7 different sirtuins; they're found in different mitochondria and sense and regulate the energy status in
locations in all cells; SIRTl, SIRT6 and SIRT7 are in the this organelle. Such as activating decoupling proteins to
nucleus, SIRT3, SIRT4 and SIRTS are in mitochondria, SIRT2 either make energy or heat in white and brown fat. SIRT3
is in the cytoplasm.[2l] And although sirtuins direct the inhibits glycolysis and glucose oxidation when adipocytes
biochemical pathway to utilize stores of fat for energy are not able to be used for fuel. SIRT3 then facilitates
during dry fasting, they act very differently when the body gluconeogenesis by triggering ~·oxidation in mitochondria
is starved of food while being hydrated. in hepatocytes in the liver and in skeletal muscles, t~
SIRTl has emerged as a regulator of glucose process pyruvate into oxaloacetate promoting ketogenesis
metabolism. During gluconeogenesis SIRTl has a dual ~.<!. I from amino acids.[25,26] SIRT4 exhibits a negative
intricate role. ,.,,' . ,. _.".. regulatory role fa"yards fatty acid oxidation. SIRTS
In the short·term phas~ 3!...e. water fast, during the activates a ketogenic enzymtf ,',s'."timulate ketogenesis that
transition out of glYsPgenolysis, SIRTl induces decreased further reduces fatty acid oxidation.
hepatic gIUc.c-)Eo production by suppressing CRTC2; a key SIRT6 indirectly down regulates hepatiC lS1!llCOS!
melihrtor of early phase gluconeogenesis.[n] Also during production, plays a critical role in glucose homeostasis and
the early phase of water fasting, SIRTl destabilizes a regulates fat metabolism by controlling lipid storage under
hepatic transcription factor for lipogenesis and represses starvation stress based on upstream chemical signals from
fatty acid synthesis, further confounding ketogenesis. hydration level reactions.[27,28]
During prolonged water fasting, SIRTl reinforces the SIRT7 is involved with lipogenesis for fat accumulation
gluconeogenic transcriptional program to start breaking and storage. During gluconeogenesis it's a gate keeper for
down vital body mass to sustain plasma glucose
I
lipolysis in case dehydration occurs.
production.[23] Therefore, sirtuins redirect the production of plasma
SIRT2 is predominantly a cytoplasmic protein and glucose via gluconeogenesis as a reaction to hydration.
pretty abundant in adipocytes. SIRT2 reduces the amount Gluconeogenesis digests muscle for its alanine and 16
of lipids, taken from fat cells in a water fast, and enhances other amino acids from vital body mass as the water fast
gluconeogenesis during times of glucose deprivation.[24]
SIRT2 fa~ilitates lipolysis during nutrient deprivation and
dehydration but not when the body is fully hydrated. The
I continues.[16-19! And this violates the second cardinal rule
of fasting to protect protein mass.
24 2S
Chapter 4
The longer a person stays on a water fast, the more vital
body mass is lost and the higher the risk of mortality. The Autophagy - Cellular l+Iousekeeping
loss of tissue from vital organs, in some cases, is
irreversible and you risk heart failure.[14) In fact, at least (( Detoxify or die. 1/
three people have died from sudden heart failure while -Sherry Rogers
using water fasting to treat obesity.[17,20] Water fasting
can come with a steep price.
Dry fasting is the first step to radical life extension because
it maintains an extended period of autophagy to clean out
Gluconeogenesis restarts the engine on the airplane but
years of stored inner-cellular trash and age markers to
you're drilling holes in the airplane to stay aloft ... you
restore youthful ce!lular function.
can't stay aloft very long.
.~ . There's an ancient Babylonian proverb from 220CgC that
perhaps you've heard before:
"Cleanliness is next to godliness. II
Gods are immortal. Pay close attention ...

The word autophagy is from the ancient Greek and reveals
its meaning; 'auto' means self and 'phagy' means to eat.
The literal meaning of autophagy is 'self-eating.' It's the
body's self-correcting system that operates when
digestion is interrupted.[55j
Do you eat or drink when you're asleep?

Sleep is dry fasting. Sleep is a period with no food and no
water that stimulates a nightly period of autophagy.
Autophagy is the primary degradative pathway for
recycling cell parts, digesting bacteria, viruses and
damaged proteins as well as delivering nutrients into cells
and waste out of the cells.
26
27
Healing is designed into our genetics to turn on during dissolve and recycle old parts in a specialized organelle -
periods of not eating. Hippocrates recognized this the lysosome.
phenomenon over 2000 years ago. Autophagy is totally reliant on Iysosomes
Sleep is a rest period for the digestive system and The way to conceptualize Iysosomes is to imagine that
resets the daily hormone system. Sleep allows the cells are like your house and that your house has little
hippocampus to perform memory sorting to send short ovens (Iysosomes) to burn trash. If the ovens can't burn
term memories into long term memory storage.[37] trash, the trash starts accumulating and rotting inside your
More importantly, sleep tells the night crew to wake house. Similarly, if Iysosomes can't get rid of the trash, in
up and clean the place; a cleaning crew that's gone in the the cell, the cell start filling up with toxic protein trash.
morning when you 'break'fast.
Eating turns off autq.phagy.t56.]-._· . -............. ~",."..-. .....T!Je~ . . are
::;~ ..... multie,le autophagic
~." ---- repair activities and all rely
-~~- .... ...- .,. . on Iysosomes. One of~naiY~~...j.Q..b~s to
.......
_ ... _ EiiaoCytosis, autophagy, exocytosis eliminate damaged Iysosomes and replace them t"G, ............
Cells are designed to do three things; bring things in from maintain their degradative function. Referring to the
the extracellular matrix - endocytosis; process the things analogy above, it's the same as throwing out old broken
that are brought in - autophagy; get things out of the cell - ovens and bringing in new ones. Autophagy is responsible
exocytosis. for the degradation of most long-lived and aggregated
Autophagy is a type of housekeeping operation inside proteins and for the way the cellular organelles such as
the cell. It's designed to deal with things brought in and to non-functioning mitochondria, peroxisomes, ribosomes
maintain the function of the internal parts of the cell to and infectious organisms are degraded, restored or
sustain optimal operation of the internal organelles. This is replaced.[59] They make sure cells can process nutrients,
an essential function; one that enables the cell to process dispose of pathogens and cellular trash then turn the
materials, correct or replace internal organelles and to ashes of their deconstruction into rebuilding materials to
later rid the cell of waste. construct new cell parts and body cells.[2,57,56}
Autophagy is strongly activated after 2 to 3 days of
. fasting and can have profound effects on healing and Tadpoles are the perfect example of how this works ...
longevity. Extending the time in autophagy, by dry fasting,
allows for more complex cellular repair. The housekeeping A frog begins life as a tadpole; basically a head and mouth
function cannot be maintained without being able to with a huge tail. When the time comes, arm and leg buds
start to appear on the body of the tadpole and it stops
28 29
The Fhoenix Frotocol The Fhoenix FrotoGol
eating. Slowly the tail disappears and a metamorphic and lipids. Lysosomes are effective because they contain
change gets underway. As the tail disappears, arms and about 50 different hydrolytic enzymes that can dissolve
legs grow in size and the tadpole transforms into a frog. just about everything you throw at them. All of the
enzymes are acid hydrolases at 5.0 pH inside the lysosome.
Where did the tail go? They're like a vat of acid. The acid environment is
It was digested in the autophagic process of protein maintained by proton pumps that transport hydrogen ions
deconstruction and re-purposed; converted into building into the lysosome to keep them acidic.
materials to create bone, nerves, blood vessels and muscle They come in a considerable variation in size and
to create the frog - like a Phoenix; born anew from the shape to accommodate the different sizes of the materials
that have been taken up for digestion like little viruses,
._ .. t~omes
-----------
ashes of the old - the digested parts of its tail in this case.
Lysos.mtl;S-~t-t~ells stomach
.--
function as the digestive system of the cell,

la~ger bacteria and big useless damaged proteins.
Lysosomes are very efficient at ending a!! types of
bacterial and even viral infections (if the cell has adequate
serving both to degrade material taken in from outside the deacetylation capability in place - see next chapter) in the
cell and to digest obsolete components inside the cell first 4 to 5 days of a dry fast. It's a pretty simple process.
itself.[58j When a bacteria is captured, by receptors on the cell
When you eat food, proteins in food are broken down membrane, the process of endocytosis brings the bacteria
in the stomach into amino acids and released into the inside the cell where it is encapsulated into an
body to be reassembled in cells into new proteins. After autophagosome vesicle (a capsule with the bacteria inside
proteins have been used for their intended purpose, some it). The vesicle holding the bacteria is combined with a
are returned into cells and digested inside Iysosomes back lysosome to dissolve it.
into amino acids again and released into the cell cytoplasm
to make new proteins. This recycling of proteins is only There are three basic types of autophagic methods inside
made possible by autophagy. The body cannot live without the cell that process materials that are brought into cells
an abundant source of available amino acids in the cells to as well as processing old organelles for replacement.
make new proteins.
How Iysosomes function Macroautophagy
Lysosomes are ball shaped containers that hold an array Macroautophagy sequesters large cargo inside a
of enzymes capable of breaking down all types of double-membrane vesicle, an autophagosome, inside the
biological polymers, proteins, nucleic acids, carbohydrates cell.
30 31
The Fhoenix F rotocol r
The Fhoenix rotocol
Macroautophagy creates a vesicle inside the cell, an encapsulate proteins into a vesicle first before they can be
autophagosome, that encapsulates materials like worn out degraded.[60]
organelles. This encapsulation vesicle is transported with
The Ubiquitin-Proteasome System (UPS)
motor proteins to the Iysosomes via microtubules and
A molecular machine, similar to a wood chipper, that takes
attached to the lysosome membrane where it merges with
large protein aggregates and breaks them into smaller
a lysosome for degradation. Macroautophagy is also the
pieces.
way new empty lysosome vesicles are constructed inside
the cell and filled up with acid hydrolase enzymes Starvation actually activates two major pathways to
delivered from the Endoplasmic Reticulum.[60] degrade most cellular proteins inside cells; CMA and the
UPS. Both are critical for the maintenance of internal cell
Microautophagy
--fur.~tll>1'Ia\ity.l541.:rhese two,catabolic pathways, working in
Microautophagy direat/}' captures -smailer cargej' inside the ._ 4~~
harmony in the cytoplasm, constitute · -- es~ential

cel! on the~/ysosorn~ membrane.
....... ,- components of cellular protein quality control which
--,-- Materials outside the cell ar.e captured on the surface of senses misfolded or d~maged pr0teins and tags them for
the cell using chemical receptors, in depressions and degradation. The ubiquitin-proteasome system is
cavities on the cell membrane, in the process of responsible for degrading 80-90% of proteins inside cells.
endocytosis. Once inside the cell, an autophagosome is These include many regulated, short-lived, abnormal,
formed to encapsulate it into a vesicle which is again denatured or damaged proteins that are broken down into
transported via motor proteins along the microtubule smaller sizes to enable chaperone mediated autophagy to
system to a lysosome to be processed.[3] shepherd the smaller bits into lysosomes.[54,62]
Chaperone Mediated Autophagy (CMA) Lysosomes in aging cells
CMA uses a chaperone (a type of protein already inside the Older cells of all types have dysfunctional CMA processes
cell) to shepherd materials directly across the lysosome that result in the build-up of proteins because they can't
membrane for degradation. be digested by their age-damaged lysosomes.[52] This is
The unique feature of CMA is how it selects damaged very likely a major contributing factor leading to cellular
proteins for degradation and how they are transferred into senescence - too much trash accumulating inside the cell.
Iysosomes. Folded proteins are first broken down by the Older cells have aging Iysosomes that can't digest
ubiquitin-proteasome system into a size allowing for direct damaged proteins, via hydrolYSis, due to the inability of
their Lamp-2A receptor sites to accept proteins for
transfer into Iysosomes. There is no requirement to
32 33
degradation.1661 Without extended autophagy to initiate microtubule system to the Iysosomes to be recycled into
renewal and replacement of old Iysosomes, cells fail amino acids for reuse . It takes at least 3 days of dry fasting
because the receptor sites on their old Iysosomes just to activate the level of autophagy to replace these worn
simply wear out. out cell organelles. Yet, if you never stop eating, that level
of repair can't be accomplished and directly contributes to
Removal of dead and senescent cells aging. This level of cellular system repair takes time, it
If you can't fix broken cells, get rid of them. Dry fasting can can't be done during the nightly period of autophagy.
activate a period of aggressive autophagy that eliminates
senescent cells. How much time does it take?
On the third day of a dry fast, bone marrow stem cells Macroautophagy and microautophagy are activated as
are stimulated to produce monocytes to create early as 30 minutes into starvation and remain highly
macro phages. M<!crophages are specialized cells that active for at least 4 to 8 hours. It's the night crew turned
psrform a type of autophagic function, outside cells, by on during sleep. If the starvation state persists for more
first engulfing senescent cells much like an than 10 hours, the cells switch to chaperone mediated
autophagosome inside a cell. Once inside the macrophage, autophagy; it's the demolition and rebuilding crew. CMA is
the UPS and CMA break down the senescent cell into small maximally up-regulated under stress conditions such as
bits that are directly transferred into Iysosomes. Once prolonged nutrient deprivation.[63] Meaning, it has low
inside the lysosome they're rapidly degraded in only S to activation with daily eating and high activation with
10 minutes.[53,62,67] extended periods of fasting. CMA is known to become
aggressively active at approximately 36 hours into fasting
Aggressive autophagy and remains at these levels until day 3 or until the body is
Every night there is some level of autophagy acting on the brought out of starvation stress.
body to try to repair some portion of the damage from the When autophagy is maintained for 5 to 7 days,
previous day. Naturally without longer periods of macroautophagy and microautophagy shepherd materials,
autophagy, you can't perform major cellular system brought into the cell, for the UPS and CMA to degrade.
correction to keep the organelles inside the cell working. These materials from broken down, non-functioning
Cellular organelles (like Iysosomes, ribosomes and proteins like cysts, tumors, excess skin, AGE's and
mitochondria) lose their ability to function efficiently over senescent cells are shuttled into Iysosomes for
time. An autophagosome encapsulates old, worn out parts degradation. This extended period of aggressive
and transports them with motor proteins along the autophagy also activates the removal and restoration of
new organelles.116,64,65]
34 35
Chapter 5
Dry fasting is the only way to produce a total whole-body
cellular metabolic restoration . This destruction by Sirtuins and Viral Infection
chemical fire of your old body tissue also results in the
building materials inside the cell to create new cells. "An ounce of NAD+ is worth Q pound of cure."
-Pam McKenzie
"In order to rise from its own ashes
a Phoenix first must burn. "
- Octavia Butler
Dry fasting is not advised during a viral infection and, in
The wide range of autophagic function fact, it can make it worse.11l6,1l7]
Autophagy and the ubiquitin-proteasome system are now
recognized as the critical housekeeping pathways in - '1'1','" sect',on 'I~ wm?'.j.c.~tlld
and much of the information
catabolism of diverse cefiuiar constituents and internal presented has only been discovered ',0', t\;~ past year.
structu res such as: Viruses can infect vulnerable cells, like the epithelial celb
Protein aggregates (aggrephagy) of the respiratory system, in a series of steps to co-opt
Lipid droplets (Iipophagy)
autophagic function . Currently, vaccines are the preferred
Iron complex (ferritinophagy)
Mitochondria (mitophagy)
method of treating viral infections by creating a way to
Peroxisome (pexophagy) stimulate antibodies. There may be a different way to
Endoplasmic reticulum (reticulophagy) defeat a virus, in the early stages of an infection, but this
Ribosome (ribophagy) information has only been recently discovered.
As well as secretory granules within pancreatic cells Autophagy has retained an evolutionary ancient ability
(zymophagy) and processes that rid the body of to eliminate most intracellular pathogens but some viruses
intracellular pathogens (xenophagy). have evolved to subvert autophagy. Viruses are ancient
Autophagy and UPS dysfunction are associated with a enem ies and have unique adaptation capabilities to thwart
variety of human pathologies including accelerated aging, our immune system and to co-opt autophagy. Viruses have
cancer, heart disease, neurodegenerative disease and evolved to utilize the autophagic machinery in specific
metabolic diseases such as diabetes.154,57] ways that assure their survival at the expense of the host.
Activating autophagy by dry fasting on a regular basis
can have desirable outcomes for longevity. Yet, there is a way to help the autophagic machinery
defeat a viral infection by improving your cellular NAD+
status.
36 37
A key function of autophagy, in antiviral defense, is the the movement of mitochondria, changing the distributed
delivery of viruses to Iysosomes for degradation but these energy production locations inside the cell.
ancient enemies are adaptive. Viruses have developed The level of intracellular calcium is one of the factors
various ways to inhibit autophagy or even employ the known to regulate mitochondrial motion. Mitochondrial
autophagic machinery for maximal viral replication. This outer membrane proteins are very sensitive to
indicates that autophagy alone, as a defense against all intercellular calcium concentration.
pathogenic attack, might prove to be not so black and Mitochondria are highly dynamic organelles that are
white. constantly in motion inside the cell to provide energy
where needed. They move along the cells microtubule
Know the enemy and their methods
transportation system on long strings of tubulin proteins
Today, there is a new family of RNA viruses thaJ:_er.e similar
that construct a sort of super highway system inside the
to zoonotic strains.: e.g., tho$e fciuiicnrom bats, pigso r
cytoplasm. Mitochondria are tethered to this system with
birds. "'The '(lUestions of their origin arise from the
-'
glycoprotein-120 coating found on COVID-19 common to
motor proteins that 'walk' them along the highway. High
intercellular calcium causes the release of the tether
-.
AIDS and Ebola; not found on other corona strains. This
between mitochondria and the microtubule-based motor
coating makes it able to bind to cells 100 to 1000 times
proteins, kinesin and dynein, thus reducing or stopping
stronger than MERS or SARS. Regardless of new strains
their microtubule-mediated movement.[12S] Viruses
and their abilities to thwart cellular defenses, all RNA
benefit from mitochondria trapped in certain cellular
viruses follow a known invasion strategy, once cells are
locations for location-specific energy production or
infected. Understanding their strategies can reveal the
sequestration of the mitochondrial apoptotic machinery,
way to prevent them.
to keep the host alive. In other words preventing
How a viral attack begins mitochondria to participate in the destruction of a
Host cell dysfunction, following infection with a virus, is diseased cell. Viruses first hijack the host's intracellular
always accompanied by abnormal increased intracellular Ca2+ system to achieve successful replication; in a way not
Ca2+ concentration. The host cell plasma membrane is the easily suspected.
first barrier against the invasion of viruses. Various Ca2+
Why increase the cells' calcium concentration?
channels and pumps are distributed on the cell membrane
and these membrane proteins become the direct target of Higher than normal levels of calcium stimulate
viral infection. This intracellular Ca2+ hijacking also affects acetyltransferase to begin hyper-acetylation - placing
acetyl groups on proteins and genetic codes. [llO,ll1] This
38 39
immediately causes the early acetylation of ct-tubulin on and its proteins can be moved to Iysosomes and degraded
microtubules to stabilize the virus cytoplasmic replication without ever infecting another cell .
compartments and in so doing stops mitochondria There is a way cells can perform normal deacetylation
movement.llllJ but it's a bit complicated because it involves
Hyper-acetylation is thus employed to derail understanding how viruses replicate in the first place.
autophagy from challenging the virus by changing the
I'll try to explain this as simply as I can .
internal structures of the cell. Acetylation subsequently
increases microtubule bundling and creates a new .Viruses have a complete package of codes to replicate
transportation system that preferentially moves viral Two critical processes occur once an RNA virus, like
compartments to the endoplasmic reticulum for COVID-19, gets inside the cell. The first is making
replication and viron assembly, Thereafter, this promott!s transu;ptiClfognd replica_tiq n polyproteins from virus RNA
"
transpDftation of replicated virus that are budding from genome. The second is making copieS of t he {omplete
the endoplasmic reticulum and need to be moved out of genome and the subgenomic proteins that make the vin:S
the cell, to the cell membrane.[lll, 115, 116,124J delivery shell parts; inner and outer shell and receptor
spikes.
But that's just the pregame ...
Penetration
Hyper-acetylation is needed to tag and locate the
Once a virus reaches the cell surface, the viral shell protein
subgenomic protein code start and stop transcription
spikes stimulate receptors to trick the cell to open the cell
locations on the virus RNA- copy, in order to replicate.
surface. This stimulates the calcium pumps on the cell
[l12,113J
surface to increase intercellular calcium levels and,
That's the pressure point for ending viral infection. thereby, activate the host cell's acetyltransferase.
Without acetyl markers, as instruction tags for virus Once the cell membrane opens, the virus shell
proteins synthesis, the entire virus replication operation releases the RNA+ ' sense' strand into the cytoplasm. The
abruptly ends. Ending the viral replication also ends the RNA strand is rapidly acetylated (tagged) to allow the virus
intracellular calcium imbalance, restoring the microtubule genome to be copied as well as sections of the entire code
system and mitochondria motility. The deacetylation of to be transcribed and replicated to also recreate the shell.
the microtubule system can then result in the return of The first copy is the genomic RNA- copy to make new
copies of the original virus; the RNA+.
normal transportation in the cells. The deactivated virus
Virus replication can't happen without acetylation.
40 41
Instead of employing vaccines (with their known toxic Sirtuins effect on protein synthesis
adjuvants that potentiate their response) to address Since sirtuins can deacetylate histones on both
viruses, it's far easier and safer to just interrupt the viral and host chromatin, their effect on viral replication
machinery by removing the markers to stop the genetic may be profound in that they can prevent activation of
replication ofthe invader; essentially neutering it. viral replication by removing the acetyl targets for protein
The way the cells can do this is by stimulating the synthesis synthesis. Viruses are known to manipulate host
of a signaling molecule; NAD+. epigenetic and transcription machinery by hijacking
SIRT-regulated pathway's if there aren't enough NAD+
NAD+ activates cytoplasmic SIRT2. Why is this important?
activated sirtuins to counter their attack at the beginning
New understanding of the anti-viral role of sirtuins of an infection.
The newest research in virologv I~ Jr:. the field orsiri\J!r]~
Sirtuins effect on intercellular transportation
founcUn tht!--nw;:~u$ and cytoplasm, SIRTl and SIRT2, first
NAD+ activated SIRT2 can act in antiviral defense at the
~i(jcidated in 2016 by Dr. Hanna Budayeva at Princeton
~-. immediate early stages of an infection by fighting the
University.[114] It's been further discovered that all sirtuins
acetylation of the cell and virus RNA by removing acetyl
can impact the replication of DNA and RNA viruses.
markers and repressing viral gene expression through
SIRT2 is a class 3 host NAD+ dependent
interactions with viral and host cell transcription factors
histone-deacylase (HDAC) found in the cytoplasm that
and histones.
regulates gene activity and regulates inter-cellular
Sirtuins are the reason why we have been able to
transportation along the cytoplasm micro tubule
survive for millions of years while living with viruses. When
system.[114] Histone acetylation is catalyzed by histone
the level of NAD+ activated sirtuins are not adequate to
acetyl transferases (HATs), whereas the reverse reaction is
fight off pathogens, the pathogens win. Meaning that we
performed by histone deacetylases (HDACs). Simply put,
are superior to all the pathogens depending on our cellular
NAD+ activated SIRT2 can remove acetyl markers
sirtuin status but sirtuins have to be activated by NAD+ to
anywhere in the cytoplasm, regardless of whether the host
work.
or the virus forces the host to place them on protein codes
and microtubules, to restore normal cellular NAD+ to the rescue
operation. But only if they have adequate NAD+ to Subgenomic proteins are small sections of the total virus
become activated to do so. genome that need to be transcribed to make the viral shell.
The code sections, to begin transcription, are marked with
acetyl groups. When activated by NAD+, SIRT2 can remove
42 43
The Fhoenix FrotoGol The Fhoenix FrotoGol
the acetyl groups placed on the virus RNA- Simply put, raising levels of NAD+ is the keystone in the
strands. Without the acetylation to instruct subgenomic arch of shielding the cells from the actions a virus.
proteins synthesis, the virus can't replicate and is unable
to re-infect another cell. SIRT2 removal of the acetylation And this is clearly seen in the most recent COVID-19
markers on microtubules may also enable movement of pandemic as it prefers old people to young people.
neutralized viral parts to Iysosomes for degradation.
Young people generally have more NAD+.
"Therefore, being oble to torget sirtuins provides 0 voluoble
antivirol theropeutic strotegy. Maybe the simplest way to
control these RNA viruses is through regulation of
NAD+ levels."
- Dr. Hanna Budayeva
Later In the book, I will discuss sirtuins in detail as they

directly affect DNA repair. The short story is that
starvation aka dry fasting up regulates NAD+ synthesis and
NAD+ is essential for activating sirtuins before you get sick.
The cells construct NAD+ from the essential amino acid
tryptophan; sorely lacking in the modern diet, due to the
actions of glyphosate on the food supply. Added to that,
there is a competition for tryptophan; macrophages taking
all they can find to destroy pathogens while the cells are
trying to employ it to keep sirtuins activated.
If SIRT2 is not active for lack of NAD+, to allow the cell to

shield against viral attack, the virus can take over the cells
autophagic process to use for its own needs. Basically by
stopping mitochondria movement and corrupting
autophagy (the movement of pathogenic materials to
Iysosomes for degradation).
44 45
Chapter 6
The Doctors Who Perfected Dry Fasting

"Extreme remedies are appropriate
for extreme diseases.H
- Hippocrates
Dr. L.A. Shchennikov
'The supreme art of war

is to subdue the enemy without fighting"
- Sun Tzu- The Art of War
Dr. Shchennikov patented his method of dry fasting in

1993: "The Method of Rehabilitation ofThe Body."
Dr. Shchennikov tested the technique on himself first. He
repeatedly performed 7 & 10 day dry fasts and even
46 47
experimented with a 21 day dry fast. Through his research the regime and being out in the open air and taking cool
and supervising dry fasts on thousands of patients, he showers will bring you double results for health.
discovered that an 11 day dry fast is the optimal length of
time to cure all conditions and that no further health Dr. Shchennikov suggests this list for a successful dry fast:
benefits are achieved by fasting longer.[29] -Remove food and liquid from view and do not think about
He observed that during dry fasting the body them.
absorbed moisture through the skin from evening air as -Abstain from sexual activity.
well as through baths and water procedures without -Breathe only with your nose, try not to talk, that is, carefully
drinking any water. He recommends that during the fast to save energy. Strictly keep your mouth shut. Do not spit
change the regime of the day somewhat - to walk at night saliva, swallow it. It is advisable to refrain from mouth
to fill the body with moisture from the air. Baths are also rinsing and teeth cleaning.
needed and their duration can be very significant since the -Movements should be smooth, calm . Do not make sudden
body starts sucking water through the skin creating a kind climbs, exclude unnecessary physical activity and effort.
of counter flow of liquid into the body. Therefore, it is very -Use a cool shower (keeping your mouth closed).
important to perform the mode of taking 'air baths' by -Be active but try to move slowly and calmly, do something
walking at night in cool moist air and periodically dousing. easy: read, write, knit, embroider
Splashing handfuls of water can be used 2 to 4 times a day -Be meek and humble, follow all the instructions gratefully.
using cool or cold water exclusively. In fact, being in the -Wear a lightweight, breathable natural fiber clothing like
open air especially at night and dousing with cool or cold linen.
water brings tangible benefits and relief even on the first -If possible, walk barefoot, which is a diuretic, expelling slags
day of this method. The skin begins to 'breathe' by feeding and toxins.
on moisture since the body is absorbing In 'reverse' -At night (or) early in the morning go out in fresh air.
-Periodically ventilate the room which you are in and at night
direction of excretion.
leave open a window or balcony door.
Dr. Shchennikov and Dr. Filonov both incorporate the
-Strictly follow the recommendations to safely end the fast.
earlier work of Sergei Ivanov in body 'tempering' to
strengthen the body. They both suggest pouring cold According to Dr. Shchennikov it is advisable to start with a
water on the body to lower the cold threshold on the third one-day dry fast lasting 24-36 hours once a week. Over the
day for hardening and strengthening the body. And like next 2-3 months you can increase the duration to 3-5 days.
Ivanov, advises to perform these water procedures in the To cure serious illnesses you will need to fast for a period
open air despite the weather conditions. So adherence to
48 49
of 9 to 11 days. It is advised to perform the 9 or 11 day fast increase to 120 or drop to 40 beats per minute. In some
under the supervision of a practitioner. cases nausea, dizziness, weakness, accumulation of saliva,
irritation in the throat or diarrhea is observed. Despite the
He also recognized that there must be a positive attitude fact that all these symptoms are unpleasant they do not
toward success in order to attempt and complete the pose any danger. They arise as a result of auxiliary
passage of a long course. You have to be confident in your processes of cleansing the body. Sleep becomes
abilities and as folk wisdom says: "A weak man seeks a interrupted and sleeping partially disappears so it must be
reason, a strong reason works." compensated by walking outside in cool air. Keep your
He further reminds us that even though you can bathe mouth shut during sleep. Before going to sleep wear an
and wash in water never forget that "as little as a drop af elastic headband around the jaw so that the mouth does
water taken Into the mouth violates abstinence." During not open, continue this until the end of the course.
the abstinence, save energy, do not waste it on Mentally monitor yourself to keep your mouth shut.
conversations.
By the 4th day reactions to dry fasting become evident. Urine collected from the
Blood pressure drops and the body temperature may rise. 8th to the 11th day during
This is a physiologically normal phenomenon during 'The a Shchennikov 11 day dry
Healing Abstinence' . Chills or fever may occur depending fast reveals how much slag
on the condition of the patient and the symptoms of their is flushed out of cells.
disease. At this stage there is a redistribution of yin and These are the sequestered
yang energies and their interaction. For example, there is a metabolic byproducts of
decrease in the cold threshold and an associated digestion that cannot be
normalization of thermoregulation processes, which can normally eliminated.
manifest as hot flashes that require the use of cold water This represents many years
to stabilize the patient's condition. However colds, of accumulation.
pharyngitis, laryngitis, tonsillitis and rhinitis are cured .
Slag Produced During Days 8 • 11
By the 7th to 8th day there is usually a bad taste in the

mouth, a coating on the tongue and a bad smell on the
tongue but keep your mouth closed. The pulse rate may
50 Sl
The f'hoenix r rotoeol r
The Fhoenix rotoeol
Dr. Shchennikovs' method is proven to be effective for a Dr. Shchennikov 11 Day Dry Fasting Method
wide variety of diseases in different age groups with a 95
percent success rate. His clinical results are nothing short In the words of Dr. Shchennikov ...
of miraculous:
Conditions resolved with dry fasting
" General recovery and

" Manic-depression
rejuvenation of the body
" Obsessive states Day 1- Stop consuming all food and water
" Improves metabolism
Strengthens a persons' faith
" Hereditary mental disorders
Severe head trauma-severe
-Basically the first day passes unnoticed, if there is no first
" in their abilities " concussion - only short
reaction of fea r of hunger.
Improves thought processes courses of 1-3-5 days -Weight loss is from 1 to 1_5 kg.
""
""
Promotes spiritual Encephalitis
development Toxoplasmosis Day 2
" Cleanses: the skin, the
digestive tract, the kidneys " Inflammatory diseases of
central nervous system -Weight loss is 1 kg.
" Promotes the utiliration of

" Cerebral palsy
diseased cells
" Cerebral tumors Day 3 - Entering first acidotic crisis
" Dissolves stones in the
kidneys and gallbladder " Hypothyroidism and
thyrotoxicosis
-The body switches to fat for water and nutrition.
Blood pressure varies depending on the characteristics of
" Cleans vessels of cholesterol
plaques
" Chronic diseases of the
cardiovascular system the body.
" Reduces high blood pressure
" Hepatitis -Weight loss continues to 1 kg.
""
Stage 3 and 4 cancers
Metastases " Bronchial asthma
An,lna pectoriS
" Improves the function of the

lymphatic system
"" Diseases of the nervous
system
Day4
-Pressure drops, body temperature may rise. This is a
" Stimulates the immune
" Epilepsy
physiologically normal phenomenon with Healing
system
" Schirophrenia
Abstinence as virus and bacterial infections are defeated.
" Activates the processes of
toxin removal " Condition after
chemotherapy and -Recommendations - do not be afraid of cold water, take a
" Acute renal failure radiotherapy cold shower in the morning and evening. Strictly monitor
"
""
Thrombosis Acute infections of kidney
that water does not enter the mouth I
Major focal myocardial
infarction " Hemophilia
Thrombophlebitis -Weight loss continues to 1 kg.
" Pronounced body mass

"" Grade III heart failure
deficit
" Diseases of the inner ear
52 53
DayS Day 7
-The body's signal system is activated. The most affected -This is a period of relief, emotional recovery, stabilization
organs have pains because at this time symptoms of of the body temperature and blood pressure, feeling of
hidden diseases appear, of which the patient may not lightness, joy.
know. By effort of will, and if necessary with self-massage, -Urine becomes a dark brown color as the body flushes out
these symptoms are suppressed or diminished. poisons.
-Body temperature rises and the person feels the heat. -We must rejoice!
-Blood pressure may increase or decrease depending on
the individual. Day 8 - Entering the second acidotic crisis
-You must take a cold shower, walk outside in cold air in -Usually there is a bad taste in the mouth and a bad smell
light clothing or even without it in any weather. If there is on the tongue but you cannot open your mouth. The pulse
snow, you can walk it barefoot. may increase to 120 or drop to 40 beats per minute. In
-Weight continues to decrease by about 1 kg. some cases the patient experiences nausea, dizziness,
weakness, accumulation of saliva, perspiration in the
Day 6 - Exiting first acidotic crisis throat and diarrhea. Despite the fact that all these
-During this period, the sense of smell is significantly symptoms are unpleasant they do not pose any danger.
increased. Smells that were not felt before become bright They arise as a result of auxiliary processes of cleansing
and some even unpleasant. There may be an ache in the the body.
lower back from a long standing or sitting in one pose. The -New symptoms - there is bitter saliva and irritability which
pOSition of the body must be chosen individually and try to you need to tame mentally.
move more, avoiding sudden movements. Do not lie down -If there is a slight headache and low back pain it is
except for short-term sleep during the day. necessary to kneel, touching the forehead to the ground
-Recommendations - to ventilate the room more often, go and, if necessary, stay longer in this position . Thus the
outside in any weather and temperature, it is better during general condition of the back stabilizes, blood circulation
rain or fog since moisture at this time is consumed through improves and relief comes which makes it possible to relax
breathing and condenses in the nose. This moisture can lying down or sitting in a comfortable position.
and should be swallowed - the more the better. At night -Movements should be slowed to avoid high blood
the desire to sleep during this period practically pressure.
disappears. -Pain continues in the weakest, sickest organs which is the
-Weight continues to decrease by about 1 kg. result of the process of their healing.
54 5S
-Sleep - the night sleep partially disappears. It must be Day 10 - End of second acidotic crisis
compensated by a night walk in the air. -State of indifference as time seems to drag on slowly.
-Recommendations - from 8th to 11th day drain urine into -The organism at this time has overcome the second
jars. Morning, afternoon and evening urine should be left acidotic crisis. The work on cleansing the blood and
in closed jars allowing to stand for 24 hours to see how healing the whole organism continues successfully but
much precipitation and slag is excreted from the body. boredom becomes an issue. Try to distract yourself with
-Before going to sleep tie the jaw so that the mouth does something (walking, reading, knitting, light types of
not open and continue this until the end of the course. occupational therapy).
Mentally monitor yourself to keep your mouth shut. -Continue the gymnastics of the tongue with the mouth
-Weight loss continues to 1 kg. closed.
Day 9 - The moment of 'fracture' Day 11 - The last stage before the release
-The head burns, the body temperature rises and there is a -Stay with the program to the final hour started 11 days
desire to cool it which is what it is necessary to do. There ago.
may be vomiting - a consequence of purification. Women -Carefully and leisurely prepare for acceptance of food,
can begin menstruation regardless of age and cycle. There given all the recommendations for the exit.
is an intensive release of waste products through the urine. -Completion ofthe course.
Coldness of hands and feet is observed, the soles of the
feet and palms whiten. Heart palpitation is increasing. Day 12 - Fast is over and time to exit
-On this day there is a turning point in the struggle of the -A very important stage - the completion of the course of
whole organism, aimed at renewing and purifying the Healing Abstinence infers that you have followed the strict
blood. In some cases the pulse may not be audible but you instructions set forth by the author!
should not be scared as it should be so. -This is a crucial moment which requires special stamina
-The mouth becomes sticky but keep your mouth closed and consciousness.
by making circular movements clockwise and
counter-clockwise with the tongue, touching the gums
that produces saliva that must be swallowed.
-Recommendations - to continue cooling the body with
cool, cold air or water.
56 57
The Fhoen;" FrotoGOI The Fhoen;" Frotocol
Dr. Sergei Filonov "Sometime after that I got acute sinusitis. The pain was
hell. When I tilted my head down it brought me to tears.
My reasoning was that such pain was primarily due to
edema because there was no swelling. Then I remembered
my dog and his edema. I decided I'll starve without water
until the pain passes. After the fifth day the pain wos gone
after I had gone through all the symptoms of the disease.
This was my first dry starvation. This is how I came to
believe that absolute fasting was effective and developed
the technique for people"
-Dr. Filonov
Dr. Filonovs' method is very similar to Dr. Shchennikov.
Both promote walking outside in nature to allow the skin
to absorb moisture from the air as well as sitting in cold
mountain streams to moderate the effects of fasting as it
progresses. He has outlined what you can expect from a
properly performed Anhydrous Starvation Therapy: [30)
Dr. Sergie Fllonov and his dog
An Intense Release of Stem Cells into the Blood which
"I had a dog and he would often run away from home for Activates Regeneration and Rejuvenation Processes
various reasons, sometimes for a long time. Once he The body is able to self-regenerate and self-rejuvenate.
came home very skinny and hungry it was obviously that These processes are launched under the influence of stem
he had not eaten any food. On another occasion he was hit cells . During dry fasting a process of intense body
by a drunken motorcyclist. When I examined him he was in cleansing is initiated as the body rids itself of sick and old
poor condition but most interesting is that he crawled into cells creating space in tissues for new stem cells. Stem cells
the dark barn and refused all food and water. His injury are propagated and released into the blood in higher
was primorily edema and he instinctively knew not to eat volume to occupy these vacated spaces, thereby
or drink. For seven days he stayed in the barn. It was only performing regeneration and rejuvenation of old organ
on the eighth day that he began to eat and drink water. He cells with new ones. An experiment was conducted at the
had mode a full recovery." Cryocenter headed by y. Romanov, a Doctor of Biology. His
58 59
The Fhoenix Frotocol The Fhoenix F rotocol
patient Yuri Guscho fasted a week. After one week of an acidotic crisis as quickly as possible which is achievable
preparation and a recovery period of three weeks, the thanks to dry fasting.
number of stem cells had dropped by the end of the 7th Informational Purification of the Body with Endogenic
fasting day but during recovery it soared. This experiment 'Water of Life'
proved that after fasting the body triples its production During dry fasting a process of intense cleansing begins as
and release of stem cells; an effect that lasts for several toxins are eliminated. Purification can only take place by
months. It turns out that the regular practice of dry fasting NOT ingesting exogenic (external) water and occurs with
can extend life and youth by 15 - 25 years. the cleaner high-quality metabolic water synthesized by
Removal of Edemas, Tumors and Inflammation the body. Under the extreme conditions of dry fasting, the
Dry fasting forces the body to obtain water from cells. This body must activate production of its own endogenic water
is why the body's 'superfluous' tissues (fat deposits, and only healthy cells are able to do that. Weak and sick
edemas, tumors) are eliminated faster than in the case of cells are unable to produce the 'water of life' and are
water fasting. During dry fasting metabolism changes selectively removed . However, this is not the most
fundamentally in three stages. 1. Psychological hunger important part of the process in replacing exogenic with
passes in one day. 2. On the third day the body's endogenic water. Endogenic water synthesized by the
metabolism enters a ketoacidosic state to perform body is free from external negative information. Basically
cleansing and pathogenic healing. 3. Between the 9th and 'dead' water is replaced with 'living' water while the
11th day there is a second ketoacidosic crisis which negative information held in exogenic water is eliminated.
performs chronic disease healing. During dry fasting a Without the impact of negative information held in
body goes into a state of autolysis faster than in the case external exogenic water, blood and lymph are purified
of water fasting. In autolysis a body looks for energy intensively through a sort of internal filtration process.
reserves inside itself. The body starts by burning Renewal of lymph and blood during dry fasting takes place
everything that is superfluous and harmful in the body: fat, thanks to endogenic 'water of life.' As a result, at the end
tumors, cysts and inflamed tissues. During dry fasting cells of dry fasting, two of the body's most important fluids
split faster as the body's need for both nutrients and water become almost completely pure. Correspondingly all the
increases. The longer the fast is prolonged after the body's tissues through which blood and lymph circulate
second crisis the longer it remains in a state of autolysis are purified of external content.
and the more effective the process of splitting This phenomenon of purification is one of the main
unnecessary tissues is. That is why it's important to reach advantages of dry fasting. This effect cannot be achieved
60 61
by abstinence from food only. This unique mechanism Thorough Cleansing without Supplemental Treatment
eliminates all the negative content that enters the body There is no need to combine dry fasting with enemas,
via 'external' water which cannot be achieved through of saunas and other hydrotherapeutic procedures. In fact,
any other kind of medical fasting. the use of these supplemental treatments is not
Improvement of Immunity by Reducing Inflammation recommended. During dry fasting toxins are effectively
During dry fasting, the body has a more powerful immune removed from the body thanks to 'live' endogenic
response and can fight inflammation more actively. All water. Many people appreciate that dry fasting does not
inflammations are fed by water which is clearly require the use of enemas or hydro colon therapy. We
demonstrated by the edemas containing pus and lymph have already mentioned that body temperature rises
that form near wounds on the body. When the body is during dry fasting. This mechanism not only increases the
deprived of an inflow of exogenic water it uses endogenic body's immune response it also turns each cell into a tiny
water very carefully; only for feeding healthy cells. nuclear fusion reactor which destroys everything that is
Damaged cells as well as various bacteria, viruses and superfluous, harmful or foreign.
parasites suffer from a lack of external water and die. Intensive Weight Loss Not Muscle Loss
During dry fasting people often get a fever. The increase in Metabolic changes in the course of dry fasting facilitate
body temperature that takes place during medical dry effective weight loss and long-term weight stabilization.
fasting leads to the creation of a strong immunologic Fat deposits are burnt three times faster during dry fasting
response. Fever during dry fasting is very good as it than during water fasting. Another advantage of dry
indicates that the body is fighting infections. Each cell in fasting is that the fat tissue does not fully regenerate after
the body is turned into a kind of small furnace or reactor the fast. This is because dry fasting is anti-angiogenic due
and the toxins inside it are destroyed. If a cell is too to the selective removal of superfluous tissue, like excess
damaged it's eliminated completely. The concentration of angiogenic blood vessels, that were created to fill fat cells.
biologically active substances in bodily fluids also increases. The third important advantage is that dry fasting burns
These include immunoglobulins and immunocompetent mostly fat due to the transformation of fatty acids to make
cells. The production of interferon rises, anti-tumor and endogenous water because you are not adding exogenic
anti-viral activity increases, T-cells proliferate, the water for metabolic processes. Since 90% of fat cells are
bactericidal capacity and phagocytic activity of neutrophils water, in the form of fatty acids, they disintegrate 3 - 4
increases, the cytotoxic effect of lymphocytes grows and times faster than muscle cells during dry fasting because
the growth and virulence of microorganisms decreases. they represent a higher caloric value as fuel. As a result
weight loss and toning takes place. The body becomes
52 53
slimmer and suppler. Finally, dry fasting is less expensive. where 120 white rats were divided into 4 groups. All of
In fact in every respect it's nearly free. There is no need for them were inoculated with sarcoma. As a result of the
special foods, meals or medicines. Dry fasting does not experiment there was a 0% survival rate for all the animals
result in the significant loss of muscle mass and is from the control group that were not fasted . The first
therefore the best way to treat obesity. group, inoculated before fasting had a 50% survival rate; in
Whole Body Rejuvenation the second group, inoculated during fasting had a 66%
Dry fasting has an incredible rejuvenating effect since it survival rate . In the third group where inoculation took
can force the body to eliminate weak and damaged cells place after breaking the fast there was a 100% survival
that cannot withstand the extreme conditions of autolysis. rate. A similar experiment was conducted in the USA. Rats
Cells become stronger resulting in 'healthy offspring' once were exposed to radioactive irradiation which caused
they divide or are replaced with a brand new cell from blood cancer in all animals within the control group. In the
stem cells. The skin, hair and nails glow with health and experimental group where rats fasted the percentage of
youth. Submitting the body to the extreme conditions of sick animals was 70% lower. It might seem that after
dry fasting launches the mechanism of selective removal; fasting the body would be weak and defenseless against
an internal fight between the body's weak and strong cells illnesses but in fact the oppOSite is true: having eliminated
in a competition for scarce resources. Strong, healthy and weak and damaged cells during fasting the body is
well-functioning cells remain and are increased in number. stronger in fighting illness.
This new ratio of strong cells pass on this strength by Regeneration of Energy, Purification of Energy Channels
producing new generations of healthy cells reducing the In the course of dry fasting the body' s energy is renewed .
amount of 'junk' cells in the body creating a body Brain activity increases, creative abilities emerge and the
regenerated and rejuvenated by process of elimination. soul achieves a state of harmony. Will power strengthens.
Effective Prevention of Oncological Diseases Dry fasting involves spiritual work and provides spiritual
Experimental research has shown that dry fasting is an results that are equally astonishing; negative information
effective means of disease prevention including is removed, negative energy is eliminated, energy channels
oncological disease. The experiments by Professor Y.S. are cleansed and chakras are opened. The fever
Nikolayev on white rats demonstrated that animals experienced by a person in the course of dry fasting affects
subjected to dry fasting after exposure to radiation are far not only damaged physical tissue but also negative energy.
less likely to develop blood cancer than the other rats. The Some of this material is burned and some leaves the body
experiment was conducted at Stavropol Medical Institute unable to withstand the extreme conditions of dry fasting.
Areas filled with 'hard', 'dead' water - pathological parts
64 65
The Fhoenix Frotocol The fhoenix F rotocol
of the body where negative energy is concentrated - are Dr. Filonov has also had remarkable clinical results using
resolved. These negative information areas appear long dry fasting to heal a wide range of conditions:
before the symptoms of an illness manifest. As a result of
dry fasting 'hard, dead' water disappears replaced by'live' Conditions resolved with dry fasting
endogenic water synthesized by the body. Pathology v' Ovarian cysts v' Ankylosing
disappears along with the underlying causes of various v' Uterine fibroids v' Spondylitis
diseases but remarkably psychological problems are v' Endometriosis v' Asthma
v' Infertility v' Chronic pneumonia
resolved.
v' Mastitis v' Pulmonary
A Rush of Energy - Increased Energy Reserves v' Hot flashes Sarcoidosis
Participants emerge from the dry fasting process with new v' Veast infection v' Atherosclerosis
v' Parasite infection v'
reserves of energy due to brain and neural tissue Hypertension
v' Viral Infection v' Sciatica
restoration and regeneration of mitochondria. They need v' Bacterial infection v' Herniated disk
less sleep and function more effectively. This seems v' Benign tumors v' Brain injury
counter intuitive: it would seem that a person who doesn't v' Rheumatoid arthritis v' Migraine headaches
eat or drink would lose energy instead of gaining it. But v' Osteoarthritis v' Gastritis and
v' Psoriasis
this is no paradox. The body draws energy from its disorders
v' Interstitial cystitis v' Stomach ulcer
surroundings. The intensity of this process during dry v' Chronic v' Duodenal ulcer
fasting is even higher. After breaking a dry fast the body pyelonephritis v' Pancreatitis
begins a process of super-regeneration, accumulating v' Prostatitis v' Cholecystitis
energy and creating energy reserves. The purification of v' Prostate adenoma v' Ulcerative colitis
v' Inflammation v' Irritable bowel
chakra energy channels during dry fasting allows a person
v' Gangrene v' Syndrome
to receive energy from the environment freely. The body v' Atopic dermatitis v' Hemorrhoids
itself, cleansed of blockages, is able to accumulate more v' Chronic urticaria ./ Non-Insulin
energy than before the fast. After the dry fast is broken ./ Eczema dependent diabetes
the body is overflowing with energy: 4-5 hours of sleep is
enough, a person becomes highly productive and feels
alive, optimistic and energized.
66 67
Chapter 7
We Can Win a Losing Battle

"Winning isn't everything, it's the only thing."
~ ~Mac' McKenz;e
It's time to draw on the scientific research, in the

reference materials, to explain why I think it's possible to
radically extend lifespan. Several metabolic chemical
reactions occur simultaneously, during a dry fast, that do
more than just repair cells. Processes that rely on enzymes
triggered into active or inactive states and hormone
secretions occur that may allow us to break the death
barrier.
I have coined a new term: functional immortality. It's
not immortality from a magic elixir, it's from a deeper
understanding of the chemical functionality of the human
body under nutrient stress. The body is a complex
chemical organism, operating after embryogenesis, with a
subset of original instruction cells that can be called upon
to replace old cells with immortal cells - stem cells.
Functional immortality is a condition where the body has
"I don't wont to achieve immortolity through my work,
been functionally restored, making it too young to die
I wont to ochieve immortality through not dying."
from old age.
- Woody Allen
You're about to see something, in a way, that no one else
has ever thought possible.
'The real vayage of discovery consists not in seeking

new landscapes but in having new eyes."
- Marcel Proust
68 69
Aristotle said the whole is greater than the sum of its parts.
I
systems to restore cellular function in unique ways to win
And the life force and the physical body are just that. f the war.
The body is a coordinated system of functioning
However, as Sun Tzu reminds us from The Art of War:
organs that are each a subsystem guided by the expressed
DNA protein codes on their local cellular histones. The "If you know the enemy ond know yourself, you need not
body works in harmony because all the cells in the body fear the result of a hundred battles. If you know yourself
have the same master DNA protein code library, to but not the enemy, for every victory gained you will also
perform the symphony of life; the human genome. suffer a defeat. If you know neither the enemy nor
Temporal control is maintained in each subsystem yourself, you will succumb in every battle."
organ by only being able to make a portion of the total
We know the enemy; the enemy is death. The battle for
DNA code to make their precise subset of operating
life is fought inside the cells. This is how the cells try to
system proteins; only a book from that larger library. fight that battle ...
If a page is torn out, words are changed or misspelled
or a new page is inserted, it's no longer the same book. Telomere loss
Then the story changes or is unreadable and organs trying Cells have the ability to divide to stay alive and repair
to read the damaged book age, malfunction and ultimately adjacent tissue, but can only do it so many time before
the life force leaves the physical body behind. they can't.
We are cells; cells fight our war against death In 1938, Herman Mueller discovered telomeres. He
A battle is waged daily to repair damage in an effort to found that the ends of each chromosome are protected
stay alive and it's a battle that's waged at the cellular level. from damage by repeating sequences of non-coding DNA.
Our cells have the ability to repair all the damage but Then in 1961, Leonard Hayflick discovered that a normal
these abilities are rarely activated. Sadly, because the full cell can only divide 40 to 60 times; the Hayflick Limit. In
1971, Russian biologist Alexei Olovnikov recognized that
repair capability is only infrequently active, these systems
are only able to delay death; they can't prevent it. chromosomes could not completely replicate their ends.
Cells rely on a number of pathways to ensure that the To accommodate Leonard Hayflick's idea of
limited somatic cell division, Olovnikov suggested that
damage to DNA, induced by endogenous and exogenous
DNA end sequences are lost every time a cell replicates
reagents, is repaired. The cells have layers of systems to
until the loss reaches a critical level, at which point cell
repair damage to their DNA in an effort to keep us alive.
division ends. These discoveries were then able to explain
Remarkably, dry fasting can activate these repair
why cells stop dividing.
70 71
The Fhoenix Frotoeol The Fhoenix F rotoeol
DNA protein codes are constructed as sequences of 4 human somatic cells, except for stem cells and
amino acids; Adenine, Guanine, Thymine and Cytosine in lymphocytes, telomerase activity is diminished after birth
the chromosomes. The chromosomes are protected by and telomere length shortens with each cell division.[36]
these end caps; telomeres. Telomeres are much like the It's hyper active in cancer cells but not active at a level in
plastic end on a shoelace, to keep the lace from fraying. normal cells to replace the telomere loss rate. However,
Telomeres are comprised of 3 of the 4 amino acids; this means that the Hayflick Limit of cell divisions is not a
Thymine, Adenine and Guanine in a specific sequence - limit in every case. Meaning, if you can add telomeres back
TIAGGG. Telomeres are repeating nucleotide onto to the ends of chromosomes, you can break the
sequences at each end of a chromosome: Hayflick Limit.
TIAGGG-TIAGGG-TIAGGG-etc. Paradoxically, by the time the cell reac~es the zombie
This repeating sequence protects the ends of the phase, the DNA code may have had so much me.thvlation
chromosomes from deterioration and from fusion with damage that telomere loss is not a factor in its inability to
neighboring chromosomes. Telomeres are designed to be replicate. The loss of telomeres during mitosis is only one
lost. The number of repeating TIAGGG telomeres on the reason cells can't divide. The accumulating damage from
end of chromosomes is repeated approximately 15,000 DNA repair inside the cell can also stop replication.
times in the womb and that number is reduced to 2,500
DNA damage repair
times at birth. The number of telomeres is reduced even
DNA can be repaired by a number of excision enzymes.
further, during the growth phases from infant to
The structural integrity of DNA molecules is necessary
adolescent to adult, as cells divide. It is unavoidable that
for their information storage function.[32] The Base
telomere sequences are lost each cell division and at a
Excision Removal (BER) pathway is a way the cells can
point there are too few of them to enable replication.
repair damaged DNA, to prevent apoptosis as well as
Once a cell can no longer replicate, its functionality slowly
senescence.
reduces and it transforms into a zombie-like phase;
As I said before, cells rely on a number of pathways to
senescence. It then begins secreting pro-inflammatory
ensure that the damage to DNA is fixed . The cell has the
cytokines that damage surrounding cells, like the bad
ability to construct enzymes that fix and repair code
apple in the barrel, until it either dies or is removed .
lesions and violations.
Telomerase AlkD glycosylase, a base excision enzyme, removes a
Telomerase is an enzyme that can wrap around the end of damaged nucleobase by cleaving a glycosidic bond. Unlike
a chromosome to build new TIAGGG amino acid many other base excision enzymes, AlkD does not flip a
sequences onto the ends of chromosomes.[31] In most damaged nucleobase like AAG (a similar base excision
72 73
The Fhoenix F rotowl The Fhoenix F rotocol
enzyme) enabling excision of bulky lesions (large segments expose the mitochondria to deuterium when free fatty
of DNA damage).133j Unlike other glycosylases, AlkD acids are used for the production of ATP.
captures the extra helical lesion (the damage attached to ATP keeps the lights on but if the lights dim, cells can
the DNA) to repair breaks, conformation violations and run out of the energy to function normally.
amino acid code sequence violations, that sometimes You can have your deuterium level tested. And
occur after DNA opens to transcribe a code sequence, incidentally, dry fasting is the most effective way to rapidly
during re-wrapping back onto "he DNA strand. The enzyme lower deuterium levels. Deuterium is found in water and
wraps around the unspooled gene strand, during cell one way to reduce your exposure to it, is to freeze water
division, replacing Incorrect amino acid inserts with and remove the first crust of ice. The deuterium In water
corrections and the DNA comes out restored. freezes first so pour the non-frozen water into a container
But this is a rarely activated repair mechanism and is and discard the ice.
not contributing to lifespan in any meaningful way.
Senolytics - a new weapon to fight the war
Deuterium accumulation Senolytics is an emerging field of research that identifies
Deuterium can slow the production of ATP. Deuterium phytochemical compounds to eliminate senescent cells
(heavy hydrogen) is a hydrogen atom bonded to a neutron and neutralize their pro-inflammatory cytokines.
making it twice as heavy as hydrogen. Mitochondria create It has been discovered that Fisetin, a naturally
ATP; the energy for life. The electron transport chain occurring plant flavonol, has the ability to specifically
machinery that creates ATP can be affected by deuterium target and eliminate senescent cells. Fisetin has been
when it replaces normal hydrogen. Deuterium is twice as proven to have the most potent senotherapeutic effect on
heavy and slows down the production.[34,35j The bigger senescent cells and is the most effective at reducing
concern about deuterium is not its presence but rather its senescent markers.
accumulation. Deuterium exists in the body naturally and In a recent Newsweek article, the director of the
it's involved in growth, energy storage and metabolism. Institute on the Biology of Aging and Metabolism at the
An excess of deuterium can change three-dimensional University of Minnesota, commenting on the selectivity of
structures in the body creating misshapen proteins and Fisetin to target senescent cells said:
lipids that don't function properly. Triglyceride is the
"It turns out that Fisetin is a natural product that actually
combination of glycerol and fatty acids found in fat cells.
we were able to show very selectively and effectively kills
Fatty acids are chains of hydrogen and carbon. The
these senescent cells or at least dials back their bad
hydrogen in the chain can be replaced by deuterium and
secretions or inflammatory proteins."
74 75
The most interesting finding is that Fisetin can pass the 20. When you give resveratrol to mice we found out that
blood brain barrier to also eliminate senescent cells in the they lived longer and were super healthy."
brain. This has the effect of dialing back the immune - Dr. David Sinclair
response in the brain as well as improving cognition. It's been shown in humans that resveratrol induces a dose
Fisetin has been shown to be safe and there is no evidence dependent increase in activity ,of the NAD+ synthetic
to date for either short or long-term toxicity. And, more enzyme nicotinamide mononucleotide adenylyl
importantly, no adverse effects of Fisetin have been transferase (NMNATl), @\ central enzyme in NAD
reported, even when gj~·en at high doses. biosynthesis. Activati(;y, of NMN'/)Tl by resveratrol in
Since senescent cells are a hallmark of aging and age cultured primary r.uman astrocytes and 1'T~IJrons increased
related diseases, it's a good idea to eliminate them and to NAD+ levels b~ 5 fold.
dial back their toxic secretions. As I said previously, Resveratrol, therefore, indirectly activates longev\',j'
senescent cells damage surrounding cells, like the bad enz~'''l1es and the active form, trans-Resveratrol; a potent
apple in the barrel, leading to more senescence. dntioxidant that reduces the effects of aging on cells and
Although dry fasting removes senescent cells, the cell components including cardiovascular epithelium,
Phoenix Protocol employs Fisetin, prior to fasting, to mitochondria, organs and brain cells.lllB]
further improve senescent cell removal. Regardless of The most important role of resveratrol is its ability to
whether you are going to follow the protocol or not I raise levels of NAD+ after DNA repair.
highly recommend that everyone take Fisetin to clear their DNA damage is first identified by an enzyme called
senescent cells (see page 131). PARP that requires NAD+ to work. PARP (Poly (ADP-ribose)
polymerase) has a critical signaling function at DNA
Resveratrol- a perfect weapon to fight the war damage sites that dictates the chromatin structural
"About 20 years ago we found a set of genes that controls organization to determine which DNA repair pathway is
aging. Those genes ore called sirtuins and there are seven promoted to perform DNA repair. Complex DNA damage
of them in our bodies. And whot they do is that they protect induces robust PARP activation and robust NAD+ depletion.
011 orgonisms from deterioration ond disease. Then we Employing resveratrol to restore NAD+ levels keeps the
found out that resveratrol is like the occelerotor pedal for cells protected on many fronts.
the sirtuin genes and stimulates NMN, nicotinamide Additionally, PARP's cell-wide hyperactivation also
mononucleotide, to make NAD because sirtuins don't work
without NAD. We also found that by the time you're 50 you
only have half the level of NAD that you had when you were
! down regulates ATP production because it also consumes
NAD+ found in mitochondria needed to make ATP, shifting
the metabolic reliance to enzymes to maintain energy
76
1 77
I
production. This is critical for damaged cell survival during I Therefore, by using resveratrol to increase NAD+
repair but alters the mitochondria oxygen consumption levels, it can influence a myriad of cellular processes
rate and extracellular acidification ratio. Restoring NAD+ including mitochondrial biogenesis, transcription and
levels returns normal ATP production in mitochondria, organization ofthe extracellular matrix.
reduces extracellular acidification and restores normal Naturally this makes NAD+ is a major player in skeletal
oxygen consumption levels. muscle development, regeneration, aging and disease. The
The body has an inl";al~ NAD+ salvage pathway vast majority of studies indicate that lower NAD+ levels
designed to restore t-IS\U+ levels ,fter PARP is used for are deleterious for muscle health a!1d higher NAD+ levels
genetic repair <;"linaling but as peop',~ age the salvage augment muscle health.
pathwa'I'r:, reduced in effectiveness. This is r.>ostly because As stated earlier NAD+ is critical for the activation of
tsr.: NAD+ precursors, needed for NAD synt'1.~sis, are sirtuins to deacetylate cells during viral attack to preve ...t
reduced due to insufficient dietary intake and norm,,'. loss viru':.<!s from corrupting autophagy for their replication .
over time. Like a bucket with a hole that drips 3 drops to; As we get older it's essential to use resveratrol
every 2 drops added back, over time the loss rate exceeds because it has a unique whole-cell effect on all 7 sirtuins
the replenishment rate. Resveratrol supplementation can by raising the level of NAD+ at all times. As I said earlier,
reverse this age related trend. young people have more NAD+ than old people.
It has been shown that the antioxidant protective
This is the reason young people don't get the diseases of
effects of resveratrol administration are linked to
aging.
improved mitochondrial function and a reduction of
oxidative stress. (119,120,121] The genetic clock
As indicated here, as well as in an earlier section on It should seem obvious that, after reading the information
viral infection, the most important action of resveratrol is in this chapter, the accumulated damage to DNA sets the
its effect on raising NAD+ levels. time on the battlefield to fight the war against death. All
Since SIRTl requires NAD+ to perform its gene the pills, potions and diets can only slow the pace but
silencing function as a deacetylase, higher NAD+ levels will never win the race.
invariably enhance SIRTl activity. This finding suggests Your time on the battlefield is certainly affected by the
that resveratrol may not only promote SIRTl function but luck of the draw of genetic variation but after that genetic
all seven sirtuins by enhancing NAD+ synthesis, in role of the dice, your personal habits and lifestyle choices
whole-cell systems, without it being required for direct can affect the length of time you stay in the fight...but only
sirtuin activation.ll22] for a while .
78 79
The Fhoenix Frotoeo! The Fhoenix Frotoeo!
ChapterS
But consider this :
Be it worms, whales or humans, lifespan is only based on
Aging and Age Reversal
the functionality of DNA. "You are never too old to become younger!"
- Mae West
...No matter what species you are.
Yet damage done to DNA during life can shorten lifespan

This is another complex chapter beca~se it discusses DNA
methylation. I'll do my best to keep it simple .
...No matter what species you are.
Methylation is a process whereby methyl groups, a
It' s only logical that if basic lifespan is shortened by DNA
combination of carbon and hydrogen atoms (CH3), bond to
damage, then lifespan can be lengthened by DNA repair.
- DNA at a promoter site. In genetics, a promoter site is a
i"" region along the DNA helix backbone that identifies the
location to open the DNA to read a particular gene; usually
near the amino acid cytosine . When methyl groups attach
along the helix, they stick out like a thorn on a rose bush.
When they are located at a gene promoter site, they act to
repress gene transcription. This is why methylation is the
primary cause of aging. These methyl groups can prevent a
wide range of proteins from being created, and making
proteins is how we stay alive.
Methylation occurs on two of the four amino acids in
DNA; cytosine and adenine. In some cases, methylation is
essential for tissue-specific gene expression.
Differentiated stem cells develop a stable and unique
DNA methylation pattern that regulates their
tissue-specific gene transcription . In this case, it's not bad.
But in the brain, for instance, when DNA is methylated as a
result of environmental toxins, drug exposure or neural
80 81
injury, methyl groups left at promoter sites change gene that can demethylate DNA and, furthermore, target weak
expression and mental impairment is a common side and damaged cells for removal altogether.[30j
effect. In this case, it's very bad. There is little doubt that removing these markers Is a
critical step to achieve radical life extension. I will show
Demethylation is the key to return cellular function and
later that if they are not removed, lifespan can't be
reverse aging.
radically lengthened.
Signs of methylation
Exceptionally long lived individuals (ELU's) have a low
The signs of aging are symptoms of the effects of these
amount of these markers.[lOSj When we're young our cells
thorns on the uNA and its effect on the number of
also have very low amounts of th'ese markers.
different proteins a cell can or can ' t make. It's seen as less
Youthfulness is the measure of a low amount of rep!l ir
elasticity in the skin, more wrinkles, failing eyesight,
markers and 'youthfulness' is the reflection of the ability
cognitive dysfunction, more aches and pains. Old cells
of cells to make every protein needed to express their
can't make all the proteins that a young cell can . That's
total functionality. When we' re young we haven't been
why old people look old. Old people have cells that have
alive long enough to accumulate enough markers to see a
accumulated so many of these 'thorns' that their cells can't
visible or functional difference as it relates to aging.
function as young cells anymore.
There is no reason to think that we can't restore youth
These thorns are epigenetic markers that build up in a
by returning our cells to this earlier level of functionality.
very linear and predictable way. The DNAm, GrimAge and
Aging can be arrested so long as we maintain this level of
AgeAcciGrim tests are lifespan predictor tests that use the
genomic cleanliness.
accumulation of these markers to calculate how long a
person has left to live. The way to conceptualize this problem is to imagine a life raft
Being able to remove these artifacts of repair is critical being loaded down with small lead weights. Each individual
for maintaining tight control of protein codes that weight isn't enough to sink the life raft but it's only a matter
maintain cell and organ functionality. Once signs of aging of time before there are enough weights to do so.
are evident, a body already has billions of cells with
Similarly, over time DNA methylation markers accrue and are
trillions of artifacts that must be removed to restore youth . like the small lead weights in the analogy above. Except in
Therefore, it's important to conduct a system-wide
this case, as the number of methylation markers accumulate,
removal sooner than later and, unfortunately, no dietary
they are transferred over and over to a series of new cells.
means can achieve this level of restoration. However, dry
fasting activates the cellular and autophagic repair systems
82 83
The Fhoenix F rotoeol The Fhoenix Frotoeol
All the methylation markers, created during the life of a cell, This breakthrough revealed that maintaining adequate
are passed on when it divides. The methylation markers, levels of NAD+, for sirtuin activation, is essential for
created during the life of the next generation cell, are added fighting aging. It was also a key missing puzzle piece to
to the inherited methylation markers and the sum total are understand how to arrest aging, since methylation
passed on to the following generation and so on and so on. increases with age: 43 ~ methylation in the 9 to 19 age
They build up in this way, over years, forcing later group increases up to 66% in the 20 to 79 age group. NAD
generations of cells to express the signs of aging, as these levels decrease with age ?nd .!>ese age group differences
loaded down cells struggle to maintain some measure of may correlate to the 5iow reductiol, 'n NAD+ levels in the
metabolic fun~.tl6 ri. 20 to 79 age gro',Jp. This correlates to a reduction in the
It should be easy to see that by the time people get old, amount of activated SIRT6 to keep methylation in check.
tl1efi cells have accumulated generations of repair artifacts. Of t'ne seven identified mammalian sirtulns, Slk,1i
Notwithstanding personal habits and dangerous lifestyles de,l)'letion is associated with severe symptoms of
and their possible life-shortening outcomes, the premature aging. So now we know that SIRT6 is the
accumulation of repair markers on DNA cause cellular correct fighter to battle aging.
dysfunction that accelerates aging and inevitability leads As discussed in chapter 4, NAD+ is recycled in a
to death.[103j complex salvage pathway. Adding dietary supplements like
nicotinamide riboside, trans-resveratrol and quercetin can
Or so we thought...
increase NAD+ levels to fight its loss in the 20 to 79 age
group.[1091
NAD+ (Nicotinamide Adenine Dinucleotide)
In 2016, Dr. David Sinclair discovered a previously unknown Sirtuins
role for the signaling molecule NAD+ that explained why Sirtuins have been shown to regulate lifespan. There are
our ability to repair methylation dwindles over time.[39,40] seven different sirtuins; they're found in different
locations in all cells and control just about everything.
NAD+ is now known for its role as a controller of cell
Sirtuins are a keystone in anti-aging. They participate in
damaging oxidation by activating sirtuins, especially the
multiple diverse processes including cell development,
ones in the nucleus of cells . Dr. Sinclair found epigenetic
apoptosis, stress tolerance, embryogenesis, differentiation,
modifications by 5mC-methylation of cytosine could be
proliferation, metabolism, hormone responses and aging.
demethylated by NAD+ activation of SIRT6. Meaning that a
Each of the seven sirtuins have a catalytic domain
'thorn' located at the amino acid cytosine, near a gene
region for NAD+ activation that act like a key and a lock; a
promoter site, could be removed by activating a sirtuin .ll02)
location on the molecule where NAD+, when attached to it,
84 85
The Fhoeni" F rotocol The Fhoenix F rotocol
can allow the sirtuin to activate enzymes and processes. taken by chaperone mediated autophagy into a lysosome
NAD+ is essential to enable SIRT6 to activate the enzyme and digested for reuse. Waste not, want not.
pathway for removing methylation marks on active
DNA.[411 When sirtuins in the nucleus are activated by The Base Excision Removal Pathway (BER)
NAD+, they can then influence a wide range of essential Dozens of base excision enzymes are available to cut open
cellular processes and enzymes. DNA to replace methylation damaged sections, thereby
The enzymes involved 'rIith longevity are called 'base removing methylation markers. Afterwards, they tidy up
excision enzymes' . These are need~d to clean DNA and the site so it no longer affects mRNA transcription.
mainly target nistones and transcription factors which It's now known that NAD+ plays a central role in BER. For
we'll set into in a moment.(41j Their removal of these our purposes having adequate NAD+ to activate S!RT6 to
methylation 'thorns' can restore accurate prote.in code signal ~he BER for demethylation on active DNA is an
transcription, leading to the restoration of youfi'lful essential component for radical life extension. BER is a
metabolic function in old cells and their mitochondria.[42] multi-step process that erases epigenetic markers and
restores access to protein codes.[43,44]
And as it turns out dry fosting up regulates NAD+ synthesis
to enable sirtuin activation in any age group. In simple terms, NAD+ turns on SIRT6 that turns on
enzymes that remove a variety of epigenetic modifications
The enzymes that establish, recognize and remove DNA on DNA; the thorns 'on top of' the code. And if not
methylation are broken into three classes: writers, erasers removed, these lesions can lead to mutations when cells
and readers. We are interested in the erasers because divide, hinder critical DNA transactions such as preventing
they modify and remove the methyl groups. cell division, cause protein transcription errors and even
Active DNA de methylation can occur in both dividing trigger apoptosis (cell death).[44)
and non-dividing cells. It requires enzymatic reactions to Unrepaired base damage is obviously implicated in
process the SmC-methylation at the promoter site at premature aging.
cytosine in order to revert it back to a naked cytosine.
Demethylation occurs through a series of chemical Sirtulns and hlstones
reactions that modify SmC into to a condition that is DNA is wrapped around histones that hide some codes
recognized by the base excision repair pathway to replace and expose others. Activating and deactivating code on
the modified base with naked cytosine. The methylated histones is regulated by sirtuins. Protein codes are
region is then able to be removed altogether and replaced identified for transcription by the placement of acetyl
with new cytosine. The removed methylated section is groups at a location to identify where mRNA can open
86 87
code to start the process of making a protein. Sirtuins because it can't make the proteins that keep the cell the
perform the essential act of deacetylation; removing type of cell it is.[45] It simply loses its ability to see the code
acetyl groups to deactivate the code until needed again. it needs and stops its normal function. It's not dead but
SIRT6 in the nucleus controls deacetylation on chromatin rather in a senescent state. When a cell enters the
for life extension. senescent state, it secretes toxic pro-inflammatory
The primary components of chromatin are histones cytokines that damage adjacent cells. Then, to add insult
which bind to DNA and function as 'anchors' around which to injury, senescent cells d-ccel~rate the accumulation of
the strands are spooleJ. The histone spools, in the cells of more senescent cells ..Gl!]
the organs, hide or expose protein codes to allow the cells Even a relat. ...ely low amount of serT~scent cells is
in the eyes or the liver to only make the proteins needed sufficient to cause tissue dysfunction and plays ,,' causal
to maintain function in the eyes or liver. Bu! more role in driving aging and age-related diseases. If these·
important than their role in acetylation, is their role in thcrns are not removed, a war is waged between the
demethylation. SIRT6 signals base excision removal number of cells still functioning and those that are
enzymes to cut out cytosine methylated sections in suffering from their damaged DNA. Then the count-down
malfunctioning histones and replace them. is on until the day when the still functioning cells are
over-burdened by the raging chemical fires escaping from
These methylation thorns reduce the tight control of inside of the senescent cells ... and the war is lost.
suppressed and expressed protein sequences of that cell
type and the control of cell-specific protein codes can be This condition is similar to a fireplace chimney when it
lost. As more and more of these methylation 'thorns' build becomes plugged. The plugged chimney spreads smoke and
up, less and less code is able to be read correctly and the fire into the house and the house burns down. If too many
cell gets confused as to what type of cell it is. chimneys get plugged and there aren't enough fire fighters
to put out all the fires, the entire town burns down.
This is exactly like driving with broken windshield wipers
on your car. At some point the scratches, bird dung and However if there is a sufficient amount of NAD+ to activate
dirt on the glass builds up so thick you can't see anything. SIRT6 after DNA repair, the repaired DNA can be
If you don't just stop the car you could crash. demethylated. Once these thorns that are bonded to DNA
are removed, cells can be returned to optimal protein
Similarly, when these methylation thorns on the DNA build code synthesis, gene expression and youthful expression.
up past a threshold, where cell transcription processes
can't 'see' the code, the cell stops. It stops as a safeguard We can win this losing battle!
88 89
Chapter 9
/ used to think time was the enemy but now / know it's only
the lack of battlefield know/edge that loses the war. Restoring Youth
"Some men see things as they are and ask, 'Why?'
Breaking the death barrier is within our grasp. / dream of things that never were and ask,
'Why not?'"
- Robert F. Kennedy
I am one of a growing number of r(!$~archers that are

convinced that aging is not inevitable. UndersL;)!1ding how
to maintain youthful cellular function is one of the pU1zles
to solve to attain functional immortality.
So let's start applying what we've learned.
Starvation stress stimulates the synthesis of NAD+ to
activate sirtuins to remove DNA methylation. Sirtuins
activate the BER pathway to restore genetic integrity by
removing methylation thus preventing senescence.[4ol
This functionally reverses the main cause of aging and
because of this, dry fasting is the foundation method to
reverse aging.[8SI
There is also a unique relationship between the nucleus
and the mitochondria.[48] It's been proven that during
starvation, NAD+/NADH ratios increase and activate SIRTl
that signal mitophagy to repair or replace mitochondria.
Furthermore, reaction oxygen species production is
suppressed in starved cells reducing mitochondrial
damage during mitophagy. Conversely, in the fed state
NAD+/NADH ratios fall and inhibits autophagy and
subsequently mitophagy.
90
91
)
Cellular dysfunction reversal = age reversal restored, the cells in the whole body can once again
Starvation stress, exercise, cold showers and hunger can operate like they did when they were younger and that's
activate nicotinamide mononucleotide and nicotinamide not the best part.
riboside to make NAD+ that is needed to activate Autophagy removes old weak cells, non-functioning
sirtuins. {2,3.48,49) NAD+ activated sirtuins stimulate the cells and cells with too much accumulated methylation
BER pathway to remove the methylation markers left at damage. ,
the DNA repair sites.{50,52j Once these artifacts of repair
are removed, it allow; the DNA code to once again tightly We are cells; 37.2 tr~lion ofthem
re-spool ont::; the histones. This re-establishes the tight When seen thi~ way, instead of looking at the body as a
control of the exact protein codes exposed during head, a he.irt or an arm, the same landscape url.folds
transcription, to enable an eye cell or a liver cell to restore before.!ls to be seen in a new way.
youthful protein code synthesis.
If you've read the previous chapters correctly, you can see
This is a prerequisite far extending lifespan.
what Proust said earlier about viewing the landscape with
This results in the return of youthful cellular function. This new eyes. Especially when considering what aging really is
repair capability is built into us, but this level of and what keeps you alive; it's the cells ability to deal with
system-wide restoration is never activated unless you the challenges of daily life and surviving its complex
deliberately stop eating for a period of time. environmental stressors.
Very simply, if you eat every day af yaur life, deep The cells make the connective tissues, like collagen and
system-repair isn't activated and bad autcomes became elastin, to make skin supple and to hold all the organs in
inevitable. place.
Cells in the muscles make the actin proteins that hold
What is youth? the muscle cells in bundles.
It's my view that youth is a cellular condition measured by The cells make their extracellular matrix that holds
functionality, it's not measured by years. Youthful structured water outside the cells and allow cells to
appearance is a macro expression of the cellular state of communicate with each other. Like a vast
youthful cellular functionality. 'cell-a-communication' network of secreted proteins and
Dry fasting effectively 'de-ages' cells because cells can carbohydrates that fills the extracellular spaces to help
employ autophagy to rapidly restore inner cellular
organelles. As the body's overall level of functionality is
92 93
cells bind together and regulate migration, proliferation Chapter 10

and differentiation.
Endogenous Stem Cell Therapy
Everything is made in cells or processed by cells. "/ intend on living forever; so far, so good."
- Steven Wright
When you finally see the landscape this way, youthful cells
set the stage for life extension. There is no other way.
/
I've covered a lot of Jf;round up unW now to explain how
the body's cells ,Q;"dn be restored and retul':led to youthful
function. But.
, 'Defore we get lost in the weeds here, ',need
to rem) r:>,a you of what I said on Page 2 since I'm about tc
disr.;uss stem cells. Without a doubt, stem cells are the
/ most important cells in your body for radical life extension.
"The Phoenix Protocol employs dry fasting for two unique

outcomes, rapid healing and its ability to activate adult
stem cells and that's its unexpected potential; endogenous
stem cell therapy."
"To get bock my youth / would do onything in the world, To realize this unexpected potential, stem cells have to be
except toke exercise, get up early or be respectable." woken up to start proliferating. The objective of the
- Oscar Wilde: the Picture of Dorian Gray Phoenix Protocol is to restore the entire body back to
youthful function. Everything discussed before these next
chapters is a pre-requisite to see the connection between
dry fasting and life extension. Extended lifespan requires
waking up stem cells. This has always been the barrier to
extending lifespan. We have an army several million strong
ready to fight for rejuvenation, but the army is waiting for
the call that never comes.
If adult stem cells are unable, for lack of chemical
instruction, to periodically replicate they suffer the same
94 95
The f'hoenix f'rotoeol The f'hoenix f'rotoeol
damage as any cell that can't be replaced. They can be What are stem cells?
damaged during their inactive state, leading to stem cell These are cells that have been with us from conception
senescence.[53,731 They don't burn out, they die in their and essential during our embryonic development.
sleep.[451 Then if the signal is never activated to awaken The ratio of body cells to stem cells falls rapidly after
adult stem cells to replace damaged tissue, normal body birth to around 5000/1 in adulthood or about 7,400,000
cells are called upon to divide anc repair tissue and this stem cells distributed in vari,?us tissues. About 200,000 of
subsequently results in ~"'IOmE:)'e loss during their cell this number of stem c~Ws are ;,n bone marrow making
division. blood and immune C:e Is daily. Diffe;:er',~.tt'pes of stem cells
have different .r~generatlon rates, dependin'g0r;-.t~ organ
Till!' IS normal aging; the ticking clock of telomE::~re loss that in which th~y are found, and their numbers are InfluenSP..~
progressively makes the entire body older. This int:')/itably in complex ways. The argument that you have to be
assures that all cells go down the road to senescence at"d careful with them so you don't use them up, like draining
as more senescent cells accumulate, organs malfunction a bank account, is ridiculous since they don't burn out.
and aging accelerates. Sometimes slower, sometimes However, it can safely be said that, after you reach
faster but normally this is how life ends. However ... adulthood, the number of stem cells reach a stable
"/ didn 't come here to tell you how this is going to end. population that assures, as a back-up system, you can
/ come here to tell you how it's going to begin." repair organs and tissues if damaged.
- Neo· The Matrix Normally they reside in the 220 different types of
tissues and sleep ... waiting ... for the signal.
Dry fasting turns off the stem cell 'stay asleep' signal that
prevents radical life extension ...it's a signal kept on by
Adult stem cells have been identified in many organs and
insulin levels in the blood . Glucose stimulates the pancreas
tissues including brain, bone marrow, peripheral blood,
to make insulin so if you're eating and metabolizing sugar
blood vessels, skeletal muscle, adipocytes, skin, teeth,
you can 't turn it off. It takes three days of dry fasting to
heart, gut, liver, ovarian epithelium and testes. They are
turn off all insulin production in the pancreas because only
thought to reside in a specific area of each tissue called a
then is there no glucose in the blood stream.
stem cell 'niche' and typically generate the cell types of
This simultaneously turns off the production of the stem the tissue in which they reside.(67) Stem cells are designed
cell sleep signal : Protein Kinase A. to replace damaged or malfunctioning cells with brand
... And then the army wakes up! new cells, so why don 't they do it all the time? Adult stem
cells are generally inactive after you reach adulthood
96 97
The f'hoenix f'rotoeol The f'hoenix f'rotoeol
except during injury, even injuries as simple as a paper cut. Most stem cells are designed NOT to be replicating all the
If it were possible to activate them all at once, the entire time, as it would logically lead to abnormal cell division,
body could be rejuvenated. and are activated by stresses like weight lifting or
injury. The presence of IGF1 and PKA assure stem cells are
Activating all stem cells at once inactive for this reason. When metabolism is transitioned
Protein Kinase A (PKA) is an e.nzyme creilted by a gene that to lipolysis in ketosis, du~il)g prolonged fasting, this
prevents stem cell acti~iltion~~ PKA is only turned off balance swings the other way. Sta~vation is a type of stress
after all glucose hs.; been exhaust~.'1d insulin levels are
- ~
severeL:!.~aced. PKA, (Protein Kinase A)-i"~!le of a family
that activates stem cells because it j)roduces very low
levels of IGFl and PKA. During starvation stn::';s, th.e body
of .enzymes that have mUltiple functions inC:'eHs but its is in auto\1r,agy repairing normal cells BECAUSE there i~ ; .~
~egUlation of the metabolism of glycogen, s~gar and li~idS insuli.n or PKA in the system. When this metabolic
is our focus. PKA is activated by the conversion of ATP Into ~c!ndulum swings away from sugar toward ketones it
cyclic AMP (cAMP) from adenylate cyclase. Adenylate activates stem cell regeneration. The Phoenix Protocol
cyclase is anchored on the inner side of the plasma employs this capability in a timed period of regeneration.
membrane inside cells to convert ATP to cAMP. cAMP's Scientists at the University of Southern California found
function is to activate PKA to transfer the effects of that fasting turns off the signal that prevents system-wide
extracellular hormones like glucagon and epinephrine past stem cell propagation; PKA.[74,75) Releasing this stem cell
the plasma membrane. Glucagon from the pancreas and regeneration 'brake' allows bone marrow stem cells to
epinephrine from the renal medulla are hormones that create new white blood cells - monocytes that create
seek new energy reserves in the body. These extra cellular macrophages that locate and 'eat' virus, bacteria, fungi,
hormones initiate an intracellular signaling cascade via cell parasites ... and senescent cells.
receptors that triggers the conversion of ATP into cAMP to
"PKA is the key gene that needs to shut down in order for
activate Protein Kinase A to trigger lipolysis in fat cells.
Fasting for longer than 48 hours switches metabolism these stem cells to switch into regenerative mode. It gives
the OK for stem cells to go ahead and begin proliferating
to a fat and ketone bodies based catabolism after glycogen
and rebuild the entire system," - MIT [76)
reserves are depleted, thereby reducing IGF1 and
PKA. (Longo and Mattson, 2014). Glycogen metabolism is This same team of researchers at MIT found that after
associated with the production of IGFl and PKA in its role entering ketosis, it only took 24 hours of fasting to reverse
in insulin response. the age related loss of stem cell regeneration in intestinal
wall crypt stem cells to restore the gut wall .(77)
99
'This study provided evidence that fasting induces a Stem cells in adulthood
metabolic switch in the intestinal stem cells from na Adult stem cells are designed to repair catastrophic injury
longer burning carbahydrates to burning fat instead. N
to restore tissue in order to maintain organ functionality. If
they are not activated, it invariably leads to accelerated
After stem cells wake up aging. The primary reason human lifespan is so short is
After PKA is removed fror:-: the blood stream, stem cell because the act of staying alive is confounded by the
proliferation is sign?:~d; stimulO'ting the asymmetric chemical signals cre~:~d by eating that keep the most
division phase ;,~ the stem cell niches. Adult stem cells important repair ~1stems asleep.
begin ilJ divid-e creating a daughter cell and its own Stem celll;;:usion therapy
replacement stem cell. The replacement stem cell' 15 left in Today, a temporary whole-body regeneration of tissue can
the niche. The daughter cell goes into symmetric divb}on be accomplished by infusions of cultured, lab grown stem
creating two identical cells that divide again to create foul' cells from donated umbilical cord blood or stem cells
transit amplifying cells; a phase in between stem cells and aspirated from your own bone marrow. These therapies
differentiation. These then divide again and transform into are expensive costing around $25,000 per infusion,
eight progenitor cells; cells that have achieved the depending on the clinic, and it requires leaving the country
potential to differentiate into any cell in their organ niche. to do it. Thereafter, clinics typically prescribe a cycle of
The progenitor phase takes 5 days after reaching ketosis. re-infusions at 6 month intervals. But these therapies do
Therefore, dry fasting for 7 days or longer gives all the not remove senescent cells, they just add a lot of stem
adult stem cells the time needed to wake up and divide cells - a shot gun effect.
enough times to flood the system with progenitor cells.
Endogenous stem cell therapy
Dry fasting, that lasts long enough to provide for this
By employing repeating cycles of the Phoenix Protocol you
regeneration cycle, can provide a unique, system-wide
can create successive waves of whole-body tissue
regeneration effect.
regeneration by harnessing the power of your own stem
Bone marrow-derived 'endothelial progenitor cells'
cells. After three days of a dry fast, PKA is turned off and
(EPC) are released during that flood and repair the
your own stem cells are activated to proliferate. At the
vascular wall of the entire blood system.IIo61 Successive
same time, your immune system is activated to remove
waves of this proliferation of stem cells create tens of
senescent cells. This sequence of events prepares for the
millions of progenitor cells that conduct a system-wide
propagation of millions of your own progenitor cells to
repair and restoration, because the army to fight death is
replace the removed senescent cells .
finally on the battle field .
100 101
This is a coordinated replacement by your own brand new by the mother's immune system.1311 The massive
stem cells and it's a lot cheaper - it's free. proliferation of stem cells, during embryogenesis, is from
More importa;,tly, it's an exact tissue match compared to their 10(J<'~ active telomerase preventing any telomere
the risks taken with using donated umbilical cord blood. IOSS.[36]
And speaking of exact tissue match, it's the abundance of Immune system cells prevent growth errors
stem cells during embryoger,"!sis that provides the clue During embryogenesis, terrrpon,l control of senescent cell
needed to reverse aging and re:,'_~~n to a much earlier removal and their replacement, .-:.y newly propagating
physical versio!', of you in adulthood. stem cells, is directed by immune system cells in the
mother's blood that is shared with the fetus. This chemical
But stem cell abundance is only half of the stor j, making cross talk, between stem cells and immune cells, will be
sure adult stem cells are accurately targeted to home in on discussed in the next chapter.
the correct location, to prevent defects and growth errors, A baby is born without an immune system. It takes up
is the other half. Simply put, making a new you requires a to two years for the immune system to fully develop and
lot of stem cells and they need an accurate conductor. that's why a baby needs to be breast fed.[69] A baby
Like during the time you were created. ingests the mother's immune system to stimulate its own
immune system.
Stem cells during embryogenesis
Breast milk is a form of blood and most of the
The primary role of stem cells in embryogenesis is to
leukocytes in breast milk are macrophages and neutrophils.
replace removed senescence cells. During embryogenesis,
Lymphocytes including T cells (natural killer cells) and
developmentally programmed senescence is followed by
antibody-producing B cells make up 10% of the leukocytes
macrophage infiltration for the clearance of senescent
in human breast milk. All these cells survive passage
cells and tissue remodeling.[68] New stem cells
through the infant's gastrointestinal system where they
differentiate into a new cell in the 'hole left behind:
are absorbed and influence the infant's immune
During this rapid growth, the immune system acts not only
response.[7o] The macrophages are essential for removing
as the means of removing senescent cells but also as the
senescent cells during neonatal growth. This is the wayan
accurate conductor needed to prevent growth errors and
infant employs the mother's immune system to still
birth defects.
remove developmentally programmed senescent cells. It's
During embryogenesis, disposal and replacement of
the mother's immune system cells that continue to direct
removed senescent cells is very efficient because of stem
the baby's own stem cells, during neonatal growth, when
cell availability and the tight temporal control maintained
102 103
the infants own immune system and microbiome are still Chapter 11
developing prior to weening. Telomerase Activity in Stem Cells
Conclusion "Those who are crazy enough
The immune system cells are the way stem cells are to think they can change the world usually do."
accurately targeted for homing in on the specific locations - Steve lobs
to replace removed ser.o!scent cells while preventing
growth errors duril'!:; tissue remodeling.[71,72] It also
indicates how important a new and effective immune The veracity of t'le argument in this book's premise bolls
system is for accurately remodeling your own body tissue. down to Cne thing; the loss rate of telomeres in stem
The mathematical progression of endogenous stem cell cells,
proliferation can result in several million stem cells being The foundation of radical life extension, and indeed the
distributed in all the different types of body tissue. idea of discovering how to achieve functional immortality,
Seven days of dry fasting activates enough of your own is entirely dependent on the ability of endogenous stem
stem cells for a whole body restoration. How long the cells to provide a dramatically longer cell life after
restoration lasts is dependent on an amino acid sequence replacing old cells. It would make no sense inserting cells
we have seen before; TIAGGG. that don't age well during tissue remodeling. Our body
already replaces tissue via normal cell division and we
know that outcome only too well.
As we discussed in Chapter 6, in most human somatic cells,
telomerase activity is diminished after birth so that
telomere length shortens with each cell division; the
Hayflick Limit; a 40 to 60 division time ciock.[36]
"But not stem cells."
An in vivo study of adult stem cells in 2008, indicated that
adequate telomere length is a pre-requisite for the
functionality of stem cells.
Usually the level of telomerase is low in the majority
of human stem cells, whereas it is up regulated in ones
104 lOS
The Fhoenix F rotocol r
The Fhoenix rotocol
that undergo rapid expansion. Like the stem cells in bone The larger question is if they can they self-renew and
marrow that make red blood cells, white blood cells during proliferate indefinitely in vivo.
infection, cells in the dermis making hair and even tissues The evidence is strong that they do.
with a low cell turnover such as the brain . Evidently,
function dictates the need for a more or less active In 2014, it was shown that pluripotent stem cells exhibit
telomerase profile in stem cells. high telomerase activity to maintain their extremely long
Stem cells are un;=lue; capable of generating a very and stable telomeres.(104) Such characteristics are likely
large number of committed progE:,,!tors and their key to their abilities to differentiate into diverse cell
descendants during a small number of s~lf-renewal types in vivo. Additionally, many niches have been
divisions. As inferred above, one important function of identified to hold a small percentage of a unique type of
telomerase, in hematopoietic stem cells (HSC), is to redli'ce pluripotent stem cells like fat, dermis, bone and gut called
the rate of telomere loss during the period of rapid cell 'Muse' stem cells.
division; preventing premature critical shortening of Suffice it to say, pluripotent stem cells can provide the
.,
telomeres and loss of telomere function. necessary continual regeneration of telomeres by active
Some studies indicate that in the presence of growth telomerase; approaching the immortality of emb~i',;~ ,
factors, some hematopoietic stem cells are capable of stem cells . From the last chapter: _
~~
more than 100 population doublings.
This is a pertinent finding since dry fasting stimulates The massiveproljJ,f!.!':lclon of stem cells during
the release of human growth hormone; a growth factor embryog~nesir;-'Is "tram their 100% active telomerase
released during the same time as stem cell activation and ~~ting any telomere loss. 1361
proliferation coincidentally during the protocol.
Telomerase activity in pluripotent stem cells
"-
And there is a readily available source of pluripotent stem
HSC's may have better than normal cell telomerase cells, perfectly sIJited for radical life extension, released at
activity but it's quite a bit different in pluripotent stem the beginning of a dry fast.
cells. Pluripotent stem cells (PSCs) have the potential to
produce any types of cells, from all three basic germ layers, The A(T) team
and the capacity to self-renew and proliferate The best source of stem cells to initiate tissue remodeling
indefinitely in vitro. (104) are the ones released first; Muse-AT stem cells from your
106 107
\
The Fhoenjx Frotocol

i The Fhoenjx Frotocol
Chapter 12
own adipose tissue (AT). They are released into the blood
stream on day 3 of a dry fast when PKA levels drop. Muse AT Stem Cells
Muse-AT stem cells are pluripotent. "Great things are dane
by a series of small things brought together. "
They intrinsically retain lineage plasticity and the ability to - Vincent Van Gogh
self-renew and proliferate indefinitely; spontaneously
generating cells representative of all three germ layers
Muse stem cells were first discovered in 2010 by Mari
from a single cell.
Dezawa at Tohoku University in Sendai, Japan.[78,79]
'Muse' stands for: Multilineage differentiating stress
At the beginning of a dry fast, the immune system is in
rapid expansion mode creating millions of macrophages to enduring cells.
remove senescent cells. These vacancies can then be
A seminal paper was published in the journal, QJM: An
replaced by Muse AT stem cells. These special Muse stem
International Journal of Medicine in December, 2018 that
cells, that have indefinite proliferation capacity and active
recognized the importance of this discovery titled:[79]
telomerase, can replace any type of cell.
. ......, 'The Revolutionary Muse Cell, A Puzzle Sol'.l:l'tP
....
Do I even ;;e"eu
tc, mention that every cell that is replaced This is an incredible understatemer.t. Muse cells represent
--
by a Muse stem cell is thelt."..,;t!er... immortal?
4% of the total stem cel!s found in fat cells. These muse
cells are called Muse-AT (adipose tissue) stem cells. 180]
Muse tells are pluripotent and are found in every organ
niche.I71,79,80. 81,82,83] Pluripotent stem cells are unique
because they can immediately differentiate into any type
of cell, even nerve cells.18s,86]
I Dry fasting releases Muse-AT stem cells directly into the

blood stream where they are distributed throughout the
body. They are tough and they replicate fast.187] In fact,
they propagate at a rate second only to Wharton's jelly
from umbilical cord stem cells.184,88]
108 109
I.,
Muse AT stem cells are released from fat cells three days initiate a chemical cross talk that changes local cells to be
into a dry fast and go into rapid expansion. This unique restored. In fact, it's the stem and progenitor cell
type of stem cell actively starts differentiating into other paracrine secretions implicated in immunoregulation, cell
cell types after it enters the blood stream; starting with proliferation and migration, neovascularization and
repairing the vascular system wall and heart muscle.{7l] extracellular matrix synthesis and remodeling that
Muse cells are from one to several percent of accelerates wound healing.194,95j
mesenchymal stem cells of the bone marrow (the source As I said, Muse stem cells are pluripotent and can
of the immune system cells) adipose tissue and differentiate directly into any type of cell. Their most
dermis.189] important task, at the beginning of a fast, is to replace an
Muse cells repair tissue by transforming into any lost aging immune system with new set of immune cells;
cell types. After homing in to a tissue site, they can , induced by using this cell-to-cell paracrine signaling
I
spontaneously differentiate into dermal and epidermal between immune cells and Muse cells. This is a critical
cells.190] They can spontaneously differentiate into \ time-dependent transformation incorporated into the
neuronal cells and intravenously injected Muse cells \ Phoenix Protocol. Why is this critical?
gifferentiate into liver components after homing in on lost
ceii';ltes,[/!(i,91,92] Chemical cross talk between immune cells and st'!!':'. i:ells
It has been discovered that immur,~ system cells
Paracrine signaling \ communicate with stem _~~''Usrrii a type of chemical
cross talk.196,97,98]
Paracrine signaling is a form of cell signe!jn/J, or cell-to-cell \ This ,cp,'::j'j,(cal cross talk instructs Muse cells and newly
communication, in which a cell produces a ~hemical
signal to induce changes in nearby cells; altering the l
}
,prQr;.~gated progenitor cells to 'home-in-on ' damaged
organ or body tissue to target the location that needs
behavior of those cells, More recently it has been shown
that many of the functional improvements, attributed to \ repair and remodeling.I71] And like I said earlier, stem cells
stem cells, may be due to paracrine actions, in the host require accurate direction.
tissue, rather than cell differentiation and re-population An aged immune system can't accurately direct stem
e.g., chemically induced transformation.193] A resultant cell targeting, but at the beginning of a dry fast bone
shift in research has seen the emergence of studies aiming marrow stem cells are in rapid expansion replacing the
to elucidate the paracrine mechanisms, underlying tissue aged immune system.184j This early replacement of the
repair and regeneration, with stem or progenitor cell immune system assures that five days later, when the
transplantation .193] The chemicals secreted from stem cells stem cell propagation in the organs are at their progenitor
110 ill
phase, differentiation and repair can be accurately Chapter 13

targeted utilizing this communication between the new The Phoenix Protocol
immune system cells and new stem cells. "Half of getting what you want is
knowing what you have to give up to get it."
And finally, with millions of new stem cells providing their - Wayne Dyer
paracrine signaling, all your newly demethylated cells with
their fully functioning protein codes can be kept younger
between your protocol cycles. The Phoenix Protocol is a 7-day dry fast performed once or
twice per year; with a minimum of a six month interval
This enables the longer lifespan and younger body I between fasts. Rest periods between protocols allows
proposed on the first page of this book.
\
time for new stem cells to chemically induce restoration in
their resident tissue.
This is my method for attaining functional immortality. I\ I remind you that the Phoenix Protocol is designed to give
you a longer life in a younger body; upwards of 25 years.
_.LJALasn't kidding when I said ... 'all the parts exist to heal
illness; exte,rJd life and maybe ... even Jive forever. ' "... the regular practice of dry fasting can ext[,dld lite and
"
youth by 15 - 25 years."
The information in this bo ok proves that by periodically ~ -Dr. Filonov
l
abstaining from food and drink, for 6nl')' a week at a time, Ea5eint~ -
the body can rejuvenate cellular function to resti:iye y~uth.
• ____ ~.r., ";lnitial dry fast should begin, as Dr. Shchennikov
Can it be any simpler than that? recommends, with a one day dry fast. Then gradually
Not to put too fine a point on it but ... by the time you're 50 \ increase the number of days, as your confidence in the
method builds, until you can complete 7 days. This may
years old you've lived for 2600 weeks, that's two thousand
take some time but most people that start dry fasting find
six hundred weeks.
that it's surprisingly easy and advance to the 7-day fast
Are you willing to give up one or two weeks per year dry rather rapidly. Dry fasting is a serious undertaking that
transitions the body into a state of starvation. It takes
fasting for the possibility of getting thousands more?
commitment to both perform it and to have the mental
will power to complete it.
11 2 113
Use common sense Dry fasting as described by Dr. Shchennikov

Since most people have never experienced fasting, normal "You will not get the full benefits if you do not complete at
reactions can be misinterpreted as symptoms of a least 5 days af fasting in ketosis but if you continue to the
problem . Anxiety, fatigue, brain fog, fl uctuation in heart 7th day the repair phase will be greatly enhanced - if you
rate, fever and insomnia are common during dry fasting as choose to remain in the fast deeper problems will be fixed
various metabolic processes are being adjusted and after a second acidotic crisis at day 8 to day 11. If a chronic
repaired . As Dr. Shchennikov states, these symptoms are a illness is not eliminated during the course of a first dry fast
normal part of dry fasting and not an indication of a it's possible to repeot the course again in a month (or later)
problem. But if you feel uncomfortable during your fast, after the full exit from the previous course. This then can
you should err on the side of caution and end the fast. reactivate the healing processes to tear the disease from
You can always attempt another fast later. You need to be the root and also effectively contributes to prevention."
in the right mindset to fast in the first place, e.g., you
"want to do it" not "you have to do it".
Note: If you have health Issues, any fast longer than 3 Dry fasting as described by Dr. Filonov:
days-~".hould be done under medical supervision. "Medical dry fasting is effective if it is applied corr~':.tiy to
pass certain stages over 5, 7 and 11 days. TQ.~se stages are
If heart rate approu's.!tes 120 beats per minute during the
fast, end the fast.
-.,
punctuated by two periods.t;:,~ mildly uncomfortable
acidotic crisis periods ~!-.at provide a condition of acid pH to
Dry fasting is not indicated for the following c~ons:
stimulate t :c 'nydrolytic actions of autophagy. Autophagy
Cirrhosis of the liver, Cholelithiasis (gall stones) i1.""t
is efJ:I!{Jioyed to deconstruct biological materials that are
urolithiasis (bladder stones), thrombophlebitis (vein
pathological, age damaged, environmentally damaged or
clotting), expressed varicose veins (enlarged and twisted,
genetically altered. The crisis periods last for predictable
often appearing as a bulging, blue blood vessels that are
time periods based on cellular metabolic and autophagic
clearly visible through the skin) and blood clotting
chemical reactian times based on the relative health of the
patient. "
disorders.
114 115
The Phoenix Protocol is more than just dry fasting During the fast
The Phoenix Protocol employs a 7-doy dry fast to restore
cellulor metabolism, stimulate on endogenous generation The Phoenix Protocol
of stem cells and includes specific longevity nutraceuticals Like I said at the beginning in Chapter 2, it's time to rest
to maintain tissue regenerotion following the fast. Firstly, and relax for the next 7 days and not eat or drink anything.
Fisetin is administered for 7 days prior to the fast to start It's really that simple. Use the helpful tips at the end of
eliminating senescent cells. Following the fast, three this chapter to make it easier to complete the protocol.
specific neutraceuticals are administered, one to maintain
bone marrow production of immune cells, a polyphenol This is a great time to read books, listen to music, binge on
complex to protect new stem cell mitochondria from episodic television shows or just rest. It's not difficult,
oxidative damage and a resveratrol complex to increase maybe a little boring toward the end but you won't be
NAD+ synthesis to activate SIRTl for continued hungry or thirsty on the program.
demethylotion of DNA in cells. This regime extends the
period of tissue regeneration via stem cell poracrine Water procedures
::;~'1.aling from newly generated endogenous stem ceI/S.193] Carrying out water procedures is a must. It's advisa.bl,~ to
take a cool or cold shower morning and nj.~\'.t to moisturize
the skin. The counter flow of \,l'tI'ter through the skin is
essential for helping the iymphatic system to flush toxins.
"- ' .. Use showerll, bathing, swimming, high pressure shower
ma~sa&e, ~tc. Make sure NO water enters your mouth .
..
Physical activity
The best physical exercise is walking in fresh air. It's
suggested to walk 30 minutes or more per day. Generally,
just being outside in the open is best because the more
fresh air you breathe, the better. In addition, you can
perform rebounding to help the lymphatic system. Avoid
over exercising and fatigue .
116 \ 117
,I
Enemas (recommended by Dr. Shchennikov) Cold or Chills: Sleep or lay with a hot water bottle.
An enema is recommended before and during fasting if
Sleep: lay in front of a large room fan on high. Lay or sleep
you're prone to constipation otherwise they're not
outside at night on a chaise lounge in the dark and listen
necessary.
to nature.
If there is any hunger at all during a fast, an enema
will stop it. Coffee craving: Wake up and smell the coffee ...just don't
drink it.
What to expect
To find out what you can expect on a day to day basis, Food craving: Sniff citrus essential oils during the day, like
during your fast, refer to Dr. Shchennikovs 11 day dry fast tangerine, orange or lemon. And sniff peppermint and
description on page 53. And if you're not trying to heal a eucalyptus at night or any soothing essential oil. Use an
major illness, just stop at the end of day 7. The Phoenix essential oil diffuser to add fragrance to room air.
Protocol employs dry fasting for its stem cell regenerative Boredom: Reading or binge watching TV shows, watching
effects, it's not designed for treating disease. movies, slow walks in nature.
Hei-pfi:! tips to make dry fasting easier Grounding (Earthing): Go outside barefoot ancj. s'(and on
Dry fasting can change body temperature, like creating wet grass or the earth to get groundE!d.
fever, as illness is being' addressed. There are also changes
Anxiety: Meditate or I.',;.ten to soft music or meditation
in sleep and rest periods. Here are ~ome helpful tips to
relaxation musl,( or cuddle with a pet.
make it a little easier so you can stay with it 1111til the end .
These suggestions come from family and friends that have Hyper mental activity: Go on the internet and learn new
completed long dry fasts. things, watch YouTube videos, read articles of interest.
Morning, noon and night: Go outside and do deep
breathing, as much as you can. Breathe deeply and if
helpful, breathe through one nostril at a time to get
deeper breaths.
Fever: Go outside at night when it's cold or take cold
showers or baths. Cold moist compresses or lay in front of
a large room fan.
118 119
PROPERLY EXITING A FAST replenishment is so important: to prevent adverse

reactions before the re-introduction of food.
The process of coming out of starvation is more Your digestive system is sensitive after a fast
important than going into it. - Dr. Shchennikov When you spend 7-days fasting, your stomach and
intestines shrink in size and new tissue has been
This means that after a fast you have to gently restart regenerated, making them sensitive. The period
your digestive system. Don't overeat and above all avoid recovering from fasting should take as long as the fast
sugar and carbohydrates. The stomach has to be itself because the digestive organs must be 'restarted'
restarted slowly with water and broths like bone broth. gently. Many of the benefits of the fast will be canceled if
The pancreas has to be restarted gently with soups that it's ended incorrectly. Conversely, the benefits will be
don't stress the Insulin producing cells and restores the strengthened if ended correctly.
production of PKA - essential/or insulin production. The second critical post-fast rule is to not consume
sugar in any form; sugar laden carbonated drinks, sugar
Re-feeding syndrome substitutes like splenda, zero calorie drinks, fruit juices,
Tbf Phoenix Protocol employs post-fast liquids and grape juice and carbohydrates in general, because \\lese
supplemeni'§ to transition out of starvation by immediately foods cause immediate spikes in insuli(l. yesulting in rapid
replenishing depleted electrolytes; sodium, magnesium, weight gain . Fresh fruit can be t;!vnsumed in small amounts
phosphorus and potassium . fh,'s will prevent re-feeding on the fourth day af.\c,y exiting the fast.
syndrome. After a tast the pancreas is very sensitive and eating
Re-feeding syndrome is when too much food or liquid S'~'6oi will negate many of the benefits from dry fasting by
nutrition of specific types (e.g., protein drinks, banana over stimulating insulin production. As an example, insulin
smoothies, etc) Is consumed during the initial 2 to 3 days will stimulate fat cells to hold more fat, prevent
after a fast. mitochondria from burning fat and stimulate angiogenesis;
When the wrong foods or too much food is introduced (the creation of new blood vessels) and subsequent
post-fast, before replenishing electrolytes, it can cause an lipogenesis (the creation of new fat cells).
abrupt shift from fat metabolism back to carbohydrate More importantly there is evidence in vitro, that
metabolism. This can cause insulin secretions to spike, stimulating stem cells with insulin will turn stem cells into
triggering the production of glucose, fat and protein fat cells . It has yet to be shown in vivo but why gamble
metabolism (gluconeogenesis) in cells which can lead to with your newly generated stem cells.
edema and other issues. This is why electrolyte
120 121
The Fhoenix Frotoeol The Fhoenix Frotocol
After the Fast Fat cells have been drastically reduced in size and the
small blood vessels that service them have been reduced
The first thing to do after ending a fast: in number as well. Don't immediately grow them back by
eating sugar or overeating. Many of the benefits of the
Mix 112 tsp baking soda into 80z of water and sip this
fast, like weight loss, will be canceled if it's ended
SLOWLY over lS minutes to replenish sodium.
incorrectly.
Re-establishing electrolytes
So in the following days putting weight back on, or keeping
Take a magnesium and potassium supplement after the
it off. will solelv depend on the amount of food consumed.
fast (and every day of the recovery period to replenish
these electrolytes).
Day4-7
Beyond Tangy Tangerine 2.0 (by Youngevity) After the third day, slowly introduce normal foods but be
A complex of 90 different nutrients including essential conscious to avoid foods with sugar and carbohydrates
minerals and electrolytes. Mix 2 scoops in 10-12 ounces of (bread, pastries, cereals, bagels, etc) and remember to
cold water or mineral water and drink over the course of continue to eat small amounts (typically the size of your
the ffrst day. (Drink this daily for the next 14 days.) fist) to prevent rapid weight gain. Fruit is hot
Avoid all acid drinks - ~o citrus or vinegar recommended for the first 3 days since it contains fructose;
a form of sugar. Eat small amounts of easy to digest food
Re-feeding at any given time. Steamed vegetables, soups, salads, (no
DO NOT OVEREAT tomatoes or spices), fermented foods (sauerkraut, kimchi,
DO NOT OVEREAT , natto), yogurt and kefir, etc.
DO NOT OVEREAT (Do you get the picture?)
,
Day 1- 3 Stay hydrated and make sure you're drinking enough
Take a probiotic daily to re-establish the gut microbiome. water. Water is necessary for proper digestion.
Drink 6 to 8 glasses of liquid daily to re-hydrate. This can Food quality
be water, carbonated mineral water, coconut water (1 cup Avoid all wheat and grains, processed foods, sugar and
per day). You can also consume vegetable, beef or chicken sugary drinks. Eat a whole food diet. Significant activation
bone broth. Keep tea and coffee to a minimum if you're of metabolism and protective forces return as the body
prone to insomnia. begins to actively absorb nutrients coming from food. It's
very important at this time to eat only high-quality foods.
122 123
Avoid strenuous work Day 14

During this time it is necessary to observe a stricter The stabilization phase begins at the end of the recovery
regimen than with fasting itself; more rest. Don't take long period. This phase is characterized by a normalization of
walks, don't perform heavy physical work and don't metabolic processes in the body and nervous system.
overwork. As your nervous system and energy production You'll experience an elevated mood with more energy,
is resetting, in the first 3-5 days out of starvation, there is deeper sleep, a normalization of appetite and stabilization
an associated serge of mental energy while your body of weight.
strength is re-established. Weakness, dizziness, even
fainting can occur so don't overtax yourself. Note: Since you have created brand new boby skin cells,
you have to treat them as such and protect them from the
Post fast enema
sun. Wear 0 hat and protective clothing for at least 0
It is recommended to perform an enema, on the second month until your skin cells are strong again. Don't layout
and third day after exiting starvation, to get rid of waste
and get sunburned.
deposited in the bowel during the detoxification phase of
fasting.
Post-fast nut race utica I supplementation
To achieve the goals of the Phoenix Protocol, specific
nutraceuticals are recommended to supplement the food
I
list in the next chapter.
There are three daily supplements formulated for the

Phoenix Protocol; Stem Cell Re-Gen, Polyphenol Plus and
Resveratrol 1000 (see page 13ij.these have been
!
formulated to support new stem cell paracrine signaling,
enhance NAD+ synthesis to activate the sirtuins, to
support demethylation and prevent oxidative stress in
neural stem cell mitochondria.
I
124 12S
The Fhoenix F rotoeol The Fhoenix Frotoeol
Chapter 14
Feeding New Stem Cells

"Eat like yaur life depends on it because it does."
- Suzanne Somers
Nutritional supplements as well as certain foods have been

proven to promote the growth of human stem cells.
The combination of blueberry, green tea, L-Carnosine
and Vitamin D3 has been shown to have a potent
synergistic effect that increases proliferation of human
hematopoietic progenitors by 70%.[99,100J Spirulina has
- ,-
"Many of life's failures are people who did not realize how
close they were to success when they gave up."
been shown to protect neural stem cells and newly
- Thomas A. Edison proliferated stem cell mitochondria in the brain:
To incorporate this resear~h ',ilto the Phoenix ProtocoJ
Stem Cell Re-Gen was treated. It's recommended as a
I daily post-fast :;.upplement. Whether you decide to fast or
not it':; 11 good idea to take this supplement to strengthen
'\ your immune system.
Polyphenol Plus is another post-fast supplement
combining polyphenols and anti-oxidants that are needed
to protect new stem cells and their mitochondria from
oxidative damage. It supports demethylation and has
powerful anti-aging and anti-inflammatory properties.
ECGC found in green tea, curcumin found in turmeric,
sulforaphane found in broccoli sprouts, goji berries and
other fruits and vegetables feed neural stem cells and are
powerful cellular nutrients.[lOoJ
126 127
The Fhoenix Frotocol The Fhoenix Frotoco!
The foods listed below are scientifically recognized to

support stem cell regeneration, proliferation and prevent
oxidative damage in their mitochondria.llOl] For the sake
of your new stem cells, it's advisable to adopt as many of
these as you can into your daily diet. These foods are
beneficial to all your cells anyway, not just stem cells.llOOI
Eat from this list every day for 2 months
• 60 grams of protein: grass fed beef, pasture raised

chicken and eggs, wild caught salmon
• Y2 cup blueberries or blackberries "Immortality is not a gift,
• 2 cups green tea or supplementation
Immortality is an achievement
• SOOmg L-Carnosine
and only those who strive mightily shall possess it. "
• 3 grams spirulina
....... - ...... • 2000 IU Vitamin D3
·Edgar Lee Masters .~
• Sd6mg 21~tragalus powder .,.;-

,---
• Y4 cup goji berrieS
• 1 clove garlic
• 112 cup broccoli sprouts
Broccoli sprouts are a super food

.' -
The sulfurophane in broccoli sprouts is lOOX more
concentrated than in broccoli. Sulfurophane activates at
least 200 genetic processes via the N RF2 pathway in cells
and stimulates proliferation and differentiation of neural
stem cells. Start sprouting!
128 129
The Fhoenix Frotoeol The Fhoenix F rotoeol
No Expiration Date drinking clean water, getting deep sleep, regular exercise and
"And the LORD God said, Behold, thinking positive thoughts is a good start. Life style and life
man has become as one of us... and live forever." extension go hand in hand to assure that you pass through
. Genesis 3:22 that gateway into a healthier and longer future .
Uh, ......................... Us?

Nothing is certain and user results may vary but this idea
might provide an opportunity that few have ever realized; a
longer, perfectly healthy lifespan unending into the future.
A Longer Road Ahead Historically, these kinds of discoveries change the

landscape. Knowledge can be destructive to existing
It's almost impossible to convey how you will feel after you paradigms and taking knowledge and using it can result in
complete your first Phoenix Protocol dry fast but it will be being cast out of Eden or Olympus ... or society. In Plato's
abundantly clear that the power to heal is in your hands. Republic, the story 'The Cave ' is the perfect example of
,'ronically it's a power you've always had. This will lead to a trying to free the hypnotized of their strongly held
paradigm sh'ift .i.!1 your thinking about health and longevity. perception of the world and how strongly humar.s hold on
to their illusions. The moral of The Cave IS: unlike a horse,
you can't even lead humans to water.
This book's outrageous idea is not iUs! about dry fasting for
health and longevity, it's about giving you a new perspective; But I firmly b'8\ieve this from 1710AD:
one that allows you to actually consider how lori£ it's
"Knowledge is given to us to do good with so that others
possible to stay alive.
may light their candle at our lamp."
- Mathew Henry
The objective of the Phoenix Protocol is to restore youth by
restoring youthful cellular functionality to arrest death by With gratitude,
staying too young to die.
In every respect the Phoenix Protocol is the gateway to

August - the next immortal.. .
functional immortality. And while it can indeed create a
younger and healthier physical version of you, how you treat
that younger version is entirely up to you. Eating clean food,
130 131
RECOMMENDATIONS:
The following supplements are recommended as part of the
Phoenix Protocol. However, if you are not going to perform
the protocol, it's certainly advisable to take these
supplements to remove senescent cells, to activate your
On a freezing day in late November 1973, I was walking with longevity enzymes; the sirtuins that perform demethylation,
my father, Dr. Thomas Wesley Dunning; a surgeon and strengthen your immune system and protect your stem cells
obstetrician by trade, on his polled Hereford cattle ranch in and mitochondria.
Connersville, Indiana. We were in a pasture checking on cows
getting ready to calve and I remember him turning to me and The combination of both Resveratrol 1000 and Polyp he no I
saying ... Plus provides the polyphenolic compounds required for
extending lifespan, by increasing the activation of
"You know son, I really love delivering babies. I have strong longevity promoting sirtuins and the biogenesis and
feelings about life. I've seen a lot it begin, but as far as I'm protection of new energy producing mitochondria.
cOII~erned life doesn't begin at conception. Eggs and sperm
don't suddenly come alive; they're already alive. Life has Note: Resveratrol is oil soluble and mu~t 22 consumed with
always been there, it's survived since it began in Earths a fat such as MCT oil, coc;onlJl oil, butter, whole milk, full
primordial sea. Life is an unbroken rib6di7 of hope stretching fat yogurt etc. According to Dr. David Sinclair, resveratrol is
back billions of years. " not absorbed when taken with water (coffee, tea, soda,
etc.) since water deactivates it in as little as 15
I asked him what life's hope was ... and he said; minutes.[123]
"Simple... life's hope is to not die" 11 Supplementation for the Phoenix Protocol:
, The combination of:
Fisetin 500 to remove senescent cells.
Resveratrol 1000 to stimulate NAD+ synthesis to activate
sirtuins.
Polyphenol Plus to restore mitochondrial ATP production.
To contact August: PhoenixProtocol@yahoo.com
Stem Cell Re-Gen to regenerate a new immune system.
132 133
The Fhoenjx Frotocol The Fhoenjx Frotocol
Pre-fast nutraceuticals Enema bag (if necessary)

Flsetin SOOmg available at www.Cvtolvfe.com Purchase at local pharmacy.
98% pure Fisetin to remove senescent cells and neutralize
their pro-inflammatory cytokines. Take one Fisetin SOOmg Sprouting jar & broccoli seeds
capsule per day for a week prior to the Phoenix Protocol Purchase at a local health food store.
7-day dry fast. Take between protocols.
Post-fast nutraceuticals
Stem Cell Re-Gen available at www.Cvtolyfe.com
Nutraceuticals to support bone marrow stem cells to
produce immune system cells and protect mitochondria in
neural stem cells. Take daily between protocols.
Polyphenol Plus available at www.Cvtolyfe.com
-..
---- _An anti-aging formulation that neutralizes the effects of free
radicals to - p ~event oxidative damage. Take daily between
-.-.~".
protocols. -
Resveratroll000 available at www.Cvtolvfe..(:om
Contains the active form; trans-Resveratrol and qt.'ercetin to
support demethylation by supporting the synthesis of NAD+
to activate sirtuins. Take daily between protocols. I
Beyond Tangy Tangerine 2.0 available on Amazon .
A multi -vitamin and mineral complex. I
Additional equipment
Carbon shower filter

To safely shower during a dry fast (and anytime) these are
available at most hardware stores. The filter screws on to the
pipe and you re-attach the shower nozzle to the filter.
134 135
The Fhoenix F rotocol
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The Fry/oenix Frotocol The Fhoenix Frotocol
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140 141
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Feb 12,2018 Phannacology; 05 May 2010
109 Changes in buman sirtuin 6 gene promoter methylation during aging
Biomed Rep. 2014 Jul ; 2(4): 574-578
142 143
The Fhoenix Frotocol The Fhoenix f~rotocol
123 Properties of Resverlfltrol: In Vitro and In Vivo Studies

aboutMetabolism" Bio8vailability~ and Biological Effects in Animal Glossary
Models and Human.; Oxid Med Cell Longev. 2015; 2015
124 Atetylated Microtubules Are Preferentially Bundled Leading to Abaslc sugar: simple sugars scientifically called ,,,,onosaccharides. In
Enhanced Kinesln-I Motility; Biophys J. 2017 Oct DNA the backbone is made of alternating phosp,hates and single
3; I 13(7): 1551 ·1560 (simple) sugar molecules that act as a framewo"k to hold the
nueleobases.
12S MIRO GTP.ses in Mitochondrial Transport, Homeostasis and
Pathology; Cells. 2016 Mar; 5(1): I Adrenal medulla: the inner portion of adrenal gland that .~its on top of
126 The Role of the Anabolic Properties of Plant· versus Animal-Based the kidney. The adrenal medulla makes epinephrine.
Protein Sources in Supporting Muscle Mass Maintenance: A Antidiuretic hormone (ADH): is also known as vasopressin. ,tt activates
Cr.tical Review; Nutrients. 2019 Aug; 11(8): 1825. the adrenal medulla to release epinephrine. ,
ATP: Adenosine Tri·Phosphate is a high·energy molecule ~found in
every cell. Its job is to store and supply the cell with needed en~"gy.
Carboxylic acid: is an organic compound at the end of a fatt,v acid
attached to a chain of hydrogen and carbon atoms.
Cytokines: are a broad and loose category of small proteins that ,"' re
important in cell signaling.
Demethylation: is the chemical process resulting in the removal of a
methyl group (CH,) from a molecule.
Electrophilic: are positively charged or neutral species that accept an
electron pair in order to bond to a nucleophile.
Embryogenesis: is the process by which an embryo forms and
develops.
Epigenetic: is the study of heritable phenotype changes that do not
involve alterations in the DNA sequence. The Greek prefix epi- implies
features that are 'on top of' or 'in addition to.'
Endogenous: having an internal cause or origin.
Exogenous: caused by an agent or organism from outside the body.
Fatty acid: a carboxylic acid consisting of a hydrocarbon chain and a
terminal carboxyl group especially occurring as esters in fats and oils.
Glucagon: a hormone formed in the pancreas which promotes the
breakdown of glycogen to glucose in the liver.
GluconeogenesiS: formation of glucose within the body from
precursors other than carbohydrates.
Glucose: a simple sugar which is an important energy source in living
organisms and is a component of many carbohydrates.
144 145
I,
The Flnoenix F rotocol The Fhoenix F!'-otocol
Glycerol: a metabolic int.ermediate and a structural component of the NAD+/NADH: Nicotinamide Adenine Dinudeotide is a molecule
major classes of biolog;lCallipids like triglycerides. formed from Vitamin B3 and ATP that acts as a carrier molecule for
Glycogen: the main "lOrage form of glucose in humans. electrons and hydrogen. NAD+ becomes NADH when two electrons
Glycogenolysis: is .,the breakdown of glycogen to glucose-i-phosphate and a hydrogen atom are added to the molecule.
and glycogen. ' Osmoreceptor: a sensory receptor primarily found in the
Glycolysis: thp_ ' breakdown of glycogen into simple sugars for hypothalamus that detects changes in blood pressure.
metabolism ir, the liver to make energy. Paracrlne: a form of cell signaling or cell-to-cell com,."unication in
Glycosylase·, DNA glycosylases catalyze the first step of the process by which a cell produces a chemical signal to induce chang~s in nearby
which dam aged bases in DNA are removed and replaced. cells altering the behavior of those cells.
HippocamJpus: a region of the brain that is associated with memory. Phosphodiester: a covalent bond in RNA or DNA that holds i a chain of
Histone: Ispools around which DNA winds and playing a role in gene phosphates and sugars together.
regulati'~n. Phytochemical: are chemicals produced by plants.
Horm"ilc: an adaptive response of cells and organisms to a moderate Pituitary: the master gland of the endocrine system.
(usurilly intermittent) stress. Plasma glucose: glucose that is held in the blood.
Hyilrolysis: a chemical reaction in which water is used to break down Pluripotent: capable of developing into any type of cell.
t'.le bonds of a particular substance. Senescence: the gradual deterioration of cellular function.
Hypothalamus: produces hormones including the releasing factors Stem cell: a type of repair cell that can differentiate into a tissue cell.
that control the hormonal secretions of the pituitary gland. Temporal control: control in a region of tissue preventing growth
Ketogenesis: the biochemical process to produce ketone bodies errors during tissue remodeling.
through the breakdown offatty acids and ketogenic amino acids. Transcript mRNA: reading the exposed DNA code on histones.
Ketone: substances produced by the liver during gluconeogenesis, a Triglyceride: a triglyceride is a combination of one glycerol molecule
process which creates glucose in times of fasting and starvation. and three fatty acid molecules.
Ketosis: is a metabolic state characterized by elevated levels of ketone Vascular System: also called the circulatory system is made up of the
bodies in the blood or urine. vessels that carry blood and lymph through the body.
Lymph: a colorless fluid containing white blood cells which bathes the
tissues and drains through the lymphatic system into the bloodstream.
Lymphatic System: a collection of organs, nodes, tissues, ducts
and vessels that help to make or transport lymph.
Macrophage: a type of white blood cell that ingests foreign material.
Methylation: process by which methyl groups are added to certain
nucleotides in genomic DNA.
Mitochondria: internal cellular organelles that act like a digestive
system which takes in nutrients, breaks them down, and creates
energy rich molecules for the cell.
146 147

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Dry

The Fhoenix Frotocol

This book is dedicated to Sergei and Leonid,

No part of th is publication may be reproduced or distributed in any fonn or by

THE PHOENIX PROTOCOL Copyright IC 2020 August Dunning

INTRODUCTION [Aii"Outrageous Idea

DRY FASTING FOR R

Everyone has a list of perfect foods, everyone has the

This book will explain how, by not eating, we can heal

Dry fasting is hormetic stress. It's a nutritional challenge to

Dry fasting is a self-imposed abstinence from food and

Dry fasting is a deliberate pause of digestive function for a

The Russian doctors, who perfected dry fasting,

The body is a complex protein factory that operates

A water fast is not a fast, it's a water diet. The best

Energy production during fasting is very different when

-., actually reveals is the indiscriminate digestion of not only

"Cleanliness is next to godliness. II

Gods are immortal. Pay close attention ...

Do you eat or drink when you're asleep?

function as the digestive system of the cell,

harmony in the cytoplasm, constitute · -- es~ential

Later In the book, I will discuss sirtuins in detail as they

If SIRT2 is not active for lack of NAD+, to allow the cell to

The Doctors Who Perfected Dry Fasting

Dr. L.A. Shchennikov

'The supreme art of war

Dr. Shchennikov patented his method of dry fasting in

By the 7th to 8th day there is usually a bad taste in the

" General recovery and

" Promotes the utiliration of

" Improves the function of the

" Pronounced body mass

We Can Win a Losing Battle

It's time to draw on the scientific research, in the

'The real vayage of discovery consists not in seeking

Yet damage done to DNA during life can shorten lifespan

I am one of a growing number of r(!$~archers that are

cells bind together and regulate migration, proliferation Chapter 10

"The Phoenix Protocol employs dry fasting for two unique

The Fhoenjx Frotocol

I Dry fasting releases Muse-AT stem cells directly into the

phase, differentiation and repair can be accurately Chapter 13

Use common sense Dry fasting as described by Dr. Shchennikov

PROPERLY EXITING A FAST replenishment is so important: to prevent adverse

Avoid strenuous work Day 14

There are three daily supplements formulated for the

Feeding New Stem Cells

Nutritional supplements as well as certain foods have been

The foods listed below are scientifically recognized to

• 60 grams of protein: grass fed beef, pasture raised

• Sd6mg 21~tragalus powder .,.;-

Broccoli sprouts are a super food

Uh, ......................... Us?

A Longer Road Ahead Historically, these kinds of discoveries change the

In every respect the Phoenix Protocol is the gateway to

Pre-fast nutraceuticals Enema bag (if necessary)

Carbon shower filter

REFERENCES 16 Prolon&ed fasting as conditioned by prior 'rotein depletion: