UNIVERSITY of the ASSUMPTION

Unisite Subdivision, Del Pilar, City of San Fernando 2000, Pampanga, Philippines
COLLEGE OF NURSING AND PHARMACY
BACHELOR OF SCIENCE IN NURSING -FIRST SEMESTER,2nd YEAR

RLE 107 MATERNAL AND CHILD HEALTH NURSING

MODULE 3N: DRUG STUDY

MACANAS, EVANGELINE ANNE A.

BSN 2B

MARIE AILEEN L. DOMINGO, RN,MN

INSTRUCTOR
 UNIVERSITY of the ASSUMPTION
Unisite Subdivision, Del Pilar, City of San Fernando 2000, Pampanga, Philippines
COLLEGE OF NURSING AND PHARMACY
BACHELOR OF SCIENCE IN NURSING -FIRST SEMESTER,2nd YEAR

DRUG STUDY
DRUG NAME CLASSIFICATIO DOSAGE, MECHANISM OF ACTION INDICATION CONTRAINDICATION EFFECTS NURSING
N ROUTE OF RESPONSIBILITIES
ADMINISTRATION
& FREQUENCY
Generic Name Oxytocic Agent Dosage Increase the sodium  Indicated for  During Side Effects  When administering
 Oxytocin  10 units/mL permeability of uterine antepartum pregnancy,  Nausea oxytocin during labor,
myofibrils, indirectly period to initiate oxytocin is used  Vomiting avoid excessive
Brand Name Route of stimulate contraction of the or improve to induce labor; it  Intense or stimulation to the
 Pitocin Administration uterine muscle uterine causes uterine frequent uterus
 Intramuscular contraction contractions and contractions
Appearance  Intravenous abortion.  Redness or  Monitor any signs of
 Solution for  Indicated for irritation at the fetal distress or
infusion Frequency postpartum  As endogenous injection site aphyxia, such as
 Parenteral  Initial infusion period to induce oxytocin is  Lost of appetite decreased fetal heart
 Vial rate, 2-8 gtts contraction in the important in the  Cramping rate, arrhythmias.
third stage of breastfeeding  Stomach pain
labor and to process, oxytocin  Runny nose  Assess maternal
control has been utilized  Sinus pain or blood pressure
postpartum in women who irritation periodically and
bleeding or are experiencing  Memory compare to normal
hemorrhage problems with problems values
engorgement and
 Indicated as a breast-feeding. Adverse effects  Start a second line
complementary  Anaphylactic with standardized
therapy in the  Oxytocin may reaction concentration of
treatment of possess  Postpartum oxytocin in IV fluid
incomplete or antidiuretic hemorrhage
unavoidable effects, and  Cardiac  Insert oxytocin
abortion prolonged use arrhythmia infusion into mainline
can increase the  Fatal IV by connected to
possibility of an afibrinogenemia port nearest to IV
antidiuretic  Premature insertion site
effect. ventricular
contractions
 Document the start
 UNIVERSITY of the ASSUMPTION
Unisite Subdivision, Del Pilar, City of San Fernando 2000, Pampanga, Philippines
COLLEGE OF NURSING AND PHARMACY
BACHELOR OF SCIENCE IN NURSING -FIRST SEMESTER,2nd YEAR

 Pelvic hematoma time, end time, dose

 Subarachnoid and any changes
hemorrhage made during
 Hypertensive administration
episodes
 Rupture of the
uterus
Generic Name Ergot Alkaloids Dosage Works directly on the  Methylergonovine  Hypertension; Side effects  Monitor the blood
 Methylergenovine  1 tab, 0.2 mg uterine smooth muscle, is used to prevent toxemia;  Upset stomach pressure of the
Maleate increasing the tone, pace, or treat bleeding pregnancy; and  Vomiting patient
Route of and amplitude of rhythmic from the uterus hypersensitivity  Diarrhea
Brand Name Administration contractions. As a result, it that can happen  Headache  Inform the mother
 Methergine  Orally produces a fast and after childbirth or  Bad taste in wait at least 12 hours
persistent tetanic uterotonic an abortion. mouth after administration
Appearance Frequency action, shortening the third of the last dose of
 Pill  One tablet, 0.2 stage of labor and reducing Adverse effects methergine before
mg, 3 or 4 blood loss.  Hypertension initiating or resuming
times daily in  Seizure breast feeding
the  Headache
puerperium  Abdominal pain  Inspect for
for a  Acute myocardial discoloration before
maximum of 1 infarction administering
week.  Transient chest
pains  Notify health care
 Vasoconstriction professional promptly
 Vasospasm if uterine relaxation
 Coronary artieral becomes prolonged
spasm or if character of
 Bradycardia vaginal bleeding
 Tachycardia change
 Dyspnea
 Hematuria
 Thrombophlebiti
s
 Water
 UNIVERSITY of the ASSUMPTION
Unisite Subdivision, Del Pilar, City of San Fernando 2000, Pampanga, Philippines
COLLEGE OF NURSING AND PHARMACY
BACHELOR OF SCIENCE IN NURSING -FIRST SEMESTER,2nd YEAR

intoxication
 Hallucination
 Leg cramps
 Dizziness
 Tinnitus
 Nasal congestion
 Diarrhea
 Diaphoresis
 Palpitation
 Rash
Generic Name Prostaglandin Dosage Inhibits basal and nocturnal  Cytotec  Misoprostol is Adverse effects  Give to patients at
 Misoprostol Antiulcerants  Tab, 100 mcg gastric acid secretion (misoprostol) is contraindicated  Nausea high risk for
and 200 mcg through a direct action on indicated for during pregnancy  Diarrhea developing NSAID-
Brand Name the parietal cell. Parietal reducing the risk for use to reduce  Abdominal pain induced gastric
 Cytotec Route of cells contain receptors that of NSAID the risk of  Flatulence ulcers; give for the
Administration have high affinity for (nonsteroidal stomach ulcers  Vomiting full term of the NSAID
Appearance  Orally prostaglandins of the E anti-inflammatory associated with  Dyspepsia use
 Tablet series. drugs, including NSAIDs (the FDA-  Constipation
Frequency aspirin)–induced approved  Miscarriage  Arrange for oral and
 200 mcg, 4 gastric ulcers in indication  Excessive written explanation of
times a day patients at high bleeding the risk to pregnancy;
daily with risk of  Spotting appropriate
food complications  Cramping contraceptive
from gastric ulcer  Hypermenorrhoe measures must be
a taken; begin therapy
 Headache on the second or third
day of a normal
menstrual period

 Instruct patient to
take medication as
directed for full
course of therapy
even if feeling better.
Take missed dose as
 UNIVERSITY of the ASSUMPTION
Unisite Subdivision, Del Pilar, City of San Fernando 2000, Pampanga, Philippines
COLLEGE OF NURSING AND PHARMACY
BACHELOR OF SCIENCE IN NURSING -FIRST SEMESTER,2nd YEAR

soon as possible
unless almost time for
the next dose; do not
double dose

 Inform patient that

misprostol will cause
spontaneous
abortion. Women of
childbearing age must
be informed of this
effect through verbal
and written
information
Generic Name Prostaglandin, Dosage It binds the prostaglandin E2  Indicated for  Contraindicated Side effects
 Monitor frequency,
 Carboprost Endocrine;  250 mcg/mL receptor, causing the treatment of for  Mild fever
duration, and force of
Abortifacient myometrial contractions, postpartum hypersensitivity,  Chills
contractions and
Brand Name Route of casuing the induction of hemorrhage due acute pelvic  Numbness
uterine resting tone.
 Hemabate Administration labour or the expulsion of to uterine inflammatory  Tingly feeling
Notify physician or
 Intramuscular the placenta. Prostaglandins atony which has disease  Nausea
other health care
Appearance occur naturally in the body not responded to  Diarrhea
professional if
 Injectable Frequency and act at several sites in the conventional  Patient with  Cough
contractions are
Solution  Administered body including the womb methods of active cardiac,  Headache
absent or last more
 Ampule at 1½ to 3½ (uterus). management. pulmonary, renal than 1 min.
hour or hepatic disease Adverse effects  Monitor temperature,
intervals depe  Nervousness pulse, and BP
nding on  Epistaxis periodically
uterine  Sleep disorder throughout the
response.  Hyperthermia course of therapy.
 Flushing Large doses may
 Asthma cause hypertension.
 Wheezing Temperature
 Coughing elevation beginning 1
 Chest pain to 16 hr after
 Flushing initiation of therapy
 UNIVERSITY of the ASSUMPTION
Unisite Subdivision, Del Pilar, City of San Fernando 2000, Pampanga, Philippines
COLLEGE OF NURSING AND PHARMACY
BACHELOR OF SCIENCE IN NURSING -FIRST SEMESTER,2nd YEAR

 Hypertension and lasting for several

 Syncope hours is not unusual.
 Palpation  Auscultate breath
 Tachycardia sounds. Wheezing
 Chest tightness and sensation of chest
 Anxiety tightness may
 Chills/shivering indicate
 Dizziness hypersensitivity
 Drowsiness reaction.
 Assess for nausea,
vomiting, and
diarrhea. Vomiting
and diarrhea occur in
approximately two-
thirds of patients.
Premedication with
antiemetic and
antidiarrheal is
recommended.
 Monitor amount and
type of vaginal
discharge. Notify
physician or other
health care
professional
immediately if
symptoms of
hemorrhage
(increased bleeding,
hypotension, pallor,
tachycardia) occur.

References
 UNIVERSITY of the ASSUMPTION
Unisite Subdivision, Del Pilar, City of San Fernando 2000, Pampanga, Philippines
COLLEGE OF NURSING AND PHARMACY
BACHELOR OF SCIENCE IN NURSING -FIRST SEMESTER,2nd YEAR

Pitocin:
https://reference.medscape.com/drug/pitocin-oxytocin-343132#3

https://go.drugbank.com/drugs/DB00107

https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/018261s031lbl.pdf

Methylergenovine Maleate:

https://www.rxlist.com/methergine-drug.htm#indications

https://medlineplus.gov/druginfo/meds/a601077.htmld

https://www.emedicinehealth.com/drug-methylergonovine/article_em.htm

Miprostol 

https://www.rxlist.com/cytotec-drug.htm#side_effects

https://www.pdr.net/drug-summary/Cytotec-misoprostol-1044

https://www.scribd.com/document/204028988/Drug-Study-Cytotec

Carboprost 

https://reference.medscape.com/drug/hemabate-carboprost-tromethamine-343131#4

https://www.rxlist.com/hemabate-drug.htm#side_effects

https://www.rxlist.com/hemabate-side-effects-drug-center.htm

https://medical-dictionary.thefreedictionary.com/carboprost