2 Propanol

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2-Propanol MATERIAL SAFETY DATA SHEET

CAS No 67-63-0 SDS/MSDS

SECTION 1: Identification of the substance/mixture and of the company/undertaking


1.1 Product identifiers
Product name : 2-Propanol
CAS-No. : 67-63-0
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Industrial & for professional use only.
1.3 Details of the supplier of the safety data sheet
Company : Central Drug House (P) Ltd
7/28 Vardaan House
New Delhi-10002
INDIA
Telephone : +91 11 49404040
Email : care@cdhfinechemical.com

1.4 Emergency telephone number


Emergency Phone # : +91 11 49404040 (9:00am - 6:00 pm) [Office hours]

SECTION 2: Hazards identification


2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Flammable liquids (Category 2), H225
Eye irritation (Category 2), H319
Specific target organ toxicity - single exposure (Category 3), Central nervous system, H336
For the full text of the H-Statements mentioned in this Section, see Section 16.
Classification according to EU Directives 67/548/EEC or 1999/45/EC
F Highly flammable R11
Xi Irritant R36
R67
For the full text of the R-phrases mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram

Signal word Danger

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Hazard statement(s)
H225 Highly flammable liquid and vapour.
H319 Causes serious eye irritation.
H336 May cause drowsiness or dizziness.
Precautionary statement(s)
P210 Keep away from heat, hot surfaces, sparks, open flames and other
ignition sources. No smoking.
P261 Avoid breathing vapours.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
Supplemental Hazard none
Statements
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumulative and
toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

SECTION 3: Composition/information on ingredients


3.1 Substances
Synonyms : sec-Propyl alcohol
Isopropyl alcohol
Isopropanol

Formula : C3H8O
Molecular weight : 60,10 g/mol
CAS-No. : 67-63-0
EC-No. : 200-661-7
Index-No. : 603-117-00-0

Hazardous ingredients according to Regulation (EC) No 1272/2008


Component Classification Concentration
2-Propanol
CAS-No. 67-63-0 Flam. Liq. 2; Eye Irrit. 2; STOT <= 100 %
EC-No. 200-661-7 SE 3; H225, H319, H336
Index-No. 603-117-00-0

Hazardous ingredients according to Directive 1999/45/EC


Component Classification Concentration
2-Propanol
CAS-No. 67-63-0 F, Xi, R11 - R36 - R67 <= 100 %
EC-No. 200-661-7
Index-No. 603-117-00-0

For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16

SECTION 4: First aid measures


4.1 Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.

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In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with
water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available

SECTION 5: Firefighting measures


5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
5.3 Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information
Use water spray to cool unopened containers.

SECTION 6: Accidental release measures


6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation.
Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to
form explosive concentrations. Vapours can accumulate in low areas.
For personal protection see section 8.
6.2 Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and
place in container for disposal according to local regulations (see section 13).
6.4 Reference to other sections
For disposal see section 13.

SECTION 7: Handling and storage


7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid inhalation of vapour or mist.
Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic
charge.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are
opened must be carefully resealed and kept upright to prevent leakage.
Handle and store under inert gas. Hygroscopic.
Storage class (TRGS 510): Flammable liquids
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

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SECTION 8: Exposure controls/personal protection
8.1 Control parameters
Components with workplace control parameters
8.2 Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at
the end of workday.
Personal protective equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and approved under
appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
Body Protection
impervious clothing, Flame retardant antistatic protective clothing., The type of protective
equipment must be selected according to the concentration and amount of the dangerous
substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with
multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to
engineering controls. If the respirator is the sole means of protection, use a full-face supplied air
respirator. Use respirators and components tested and approved under appropriate government
standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.

SECTION 9: Physical and chemical properties


9.1 Information on basic physical and chemical properties
a) Appearance Form: liquid
Colour: colourless
b) Odour alcohol-like
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing Melting point/range: -89,5 °C
point
f) Initial boiling point and 82 °C
boiling range
g) Flash point 12,0 °C - closed cup
h) Evaporation rate 3,0
i) Flammability (solid, gas) No data available
j) Upper/lower Upper explosion limit: 12,7 %(V)
flammability or Lower explosion limit: 2 %(V)
explosive limits
k) Vapour pressure 43,2 hPa at 20,0 °C
58,7 hPa at 25,0 °C
l) Vapour density No data available
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m) Relative density 0,785 g/mL at 25 °C
n) Water solubility completely soluble
o) Partition coefficient: n- log Pow: 0,05
octanol/water
p) Auto-ignition 425,0 °C
temperature
q) Decomposition No data available
temperature
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
Surface tension 20,8 mN/m at 25,0 °C

SECTION 10: Stability and reactivity


10.1 Reactivity
No data available
10.2 Chemical stability
Stable under recommended storage conditions.
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
Heat, flames and sparks.

10.5 Incompatible materials


Oxidizing agents, Acid anhydrides, Aluminium, Halogenated compounds, Acids
10.6 Hazardous decomposition products
Other decomposition products - No data available
In the event of fire: see section 5

SECTION 11: Toxicological information


11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - 5.045 mg/kg
Remarks: Behavioral:Altered sleep time (including change in righting reflex). Behavioral:Somnolence
(general depressed activity).
LC50 Inhalation - Rat - 8 h - 16000 ppm
LD50 Dermal - Rabbit - 12.800 mg/kg
Skin corrosion/irritation
Skin - Rabbit
Result: Mild skin irritation
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Eye irritation - 24 h
Respiratory or skin sensitisation
No data available
Germ cell mutagenicity
No data available
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Carcinogenicity
This product is or contains a component that is not classifiable as to its carcinogenicity based on its IARC,
ACGIH, NTP, or EPA classification.

IARC: 3 - Group 3: Not classifiable as to its carcinogenicity to humans (2-Propanol)


Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
Inhalation, Oral - May cause drowsiness or dizziness.
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
Additional Information
RTECS: NT8050000
Central nervous system depression, prolonged or repeated exposure can cause:, Nausea, Headache,
Vomiting, narcosis, Drowsiness, Overexposure may cause mild, reversible liver effects., Aspiration may
lead to:, Lung oedema, Pneumonia
To the best of our knowledge, the chemical, physical, and toxicological properties have not been
thoroughly investigated.
Kidney - Irregularities - Based on Human Evidence

SECTION 12: Ecological information


12.1 Toxicity

Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 9.640,00 mg/l - 96 h


Toxicity to daphnia and EC50 - Daphnia magna (Water flea) - 5.102,00 mg/l - 24 h
other aquatic
invertebrates
Immobilization EC50 - Daphnia magna (Water flea) - 6.851 mg/l - 24 h
Toxicity to algae EC50 - Desmodesmus subspicatus (green algae) - > 2.000,00 mg/l - 72 h
EC50 - Algae - > 1.000,00 mg/l - 24 h
12.2 Persistence and degradability
No data available
12.3 Bioaccumulative potential
No bioaccumulation is to be expected (log Pow <= 4).
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and
toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects
No data available

SECTION 13: Disposal considerations


13.1 Waste treatment methods
Product
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Burn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting as
this material is highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal
company.
Contaminated packaging
Dispose of as unused product.

SECTION 14: Transport information


14.1 UN number
ADR/RID: 1219 IMDG: 1219 IATA: 1219
14.2 UN proper shipping name
ADR/RID: ISOPROPANOL
IMDG: ISOPROPANOL
IATA: Isopropanol

14.3 Transport hazard class(es)


ADR/RID: 3 IMDG: 3 IATA: 3
14.4 Packaging group
ADR/RID: II IMDG: II IATA: II
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user
No data available

SECTION 15: Regulatory information


This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture

No data available
15.2 Chemical Safety Assessment
For this product a chemical safety assessment was not carried out

SECTION 16: Other information


Full text of H-Statements referred to under sections 2 and 3.
Eye Irrit. Eye irritation
Flam. Liq. Flammable liquids
H225 Highly flammable liquid and vapour.
H319 Causes serious eye irritation.
H336 May cause drowsiness or dizziness.
STOT SE Specific target organ toxicity - single exposure
Full text of R-phrases referred to under sections 2 and 3
F Highly flammable
Xi Irritant
R11 Highly flammable.
R36 Irritating to eyes.
R67 Vapours may cause drowsiness and dizziness.

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Further information
The above information is believed to be correct but does not purport to be all inclusive and shall be
used only as a guide. The information in this document is based on the present state of our knowledge
and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Central Drug House (P) Ltd and its Affiliates shall not be
held liable for any damage resulting from handling or from contact with the above product. See
www.cdhfinechemical.com for additional terms and conditions of sale.

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