PIPH111 Lecture Guide
PIPH111 Lecture Guide
PIPH111 Lecture Guide
PERSPECTIVES IN PHARMACY
COURSE TITLE Perspectives in COURSE CODE PIPH111
Pharmacy
CREDIT UNITS 2 Units COURSE None
PREREQUISITE/S/CO-
REQUISITE
CONTACT HOURS 2 Hours Lecture COURSE PLACEMENT First Year, First
Semester
COURSE Rationale
DESCRIPTION This course deals with the basic concepts and principles of pharmacy,
skills in classifying drugs according to its therapeutic uses and basic laws
and principles that affects the different areas of pharmacy practice. The
student will be able to appreciate the different roles of pharmacists in all
areas of pharmacy practice and the pharmacist's social and professional.
Outcomes
At the end of the course, the students are expected to demonstrate
familiarity and knowledge on the basic principles of Pharmacy practice.
Students are also expected to be knowledgeable on how to classify drugs
based on their dosage form and therapeutic classification.
EXPECTED OUTCOMES:
At the end of this unit, the students are expected to:
◉ Identify the major events in the evolution of pharmacy
◉ Identify the major personalities and their contribution in the history of pharmacy.
REQUIRED READINGS
◉ http://miter.mit.edu/articlebench-boardroom-historical-developmentspharmaceutical-
industry/
CHECKLIST:
◉ Read course and unit objectives
◉ Read study guide prior to class attendance
◉ Read required learning resources; refer to unit terminologies for jargons
◉ Proactively participate in discussions
◉ Participate in weekly discussion board (Canvas)
◉ Answer and submit course unit tasks
TOPIC 1: HISTORICAL DEVELOPMENT OF
PHARMACY PRACTICE
NOTES: PHARMACY
§ It is derived from Greek word “Pharmakon”
§ art of dispensing and preparing of medicines or drugs
§ establishment and place where drugs or medicines are solved.
Pharmacist
– They are also known as druggists
– They are healthcare professionals who practice in pharmacy, the field of health sciences
focusing on safe and effective medication use.
SYMBOLS OF PHARMACY
Bowl of Hygeia The bowl with a snake coiled around it is called the
bowl of Hygeia with the serpent of Epidaurus. Hygeia
was Aesculapius’s daughter and a Greek Goddess of
health. Her symbol was a serpent drinking from a
bowl.
EVOLUTION OF PHARMACY
§ Man have several characteristics on how to treat ailments, physical and mental with
medicines. Base on archeological evidence man always search for other tools to treat his
conditions.
– Since the dawn of humanity, pharmacy has been part of everyday life. By trial and error, folk
knowledge of the healing properties of certain natural substances grew.
– In Shanidar cave burial 50, 000 years ago, Neanderthal man was buried in the shanidar
caves in northern Iraq with clusters of flowers and herbs.
– Shamans- Also known as Faith-Healers; Because both disease and its treatment involves
this world of spirits, they need a specialist who understands and could control the spirits. -
Oral rite and Manual rite
MESOPOTAMIA
Also known as the “Cradle of Civilization”
They believe that one could avoid disease by leading a righteous life and worshipping the
proper God
Mesopotamians made offerings to the ghost of their ancestors, respected taboos, and even
acquire magical accessories to keep away evil.
3 Deities/Gods
1. Ninazu – Lord physician
2. Ningishrida – son of Ninazu - carries the staff with snake around it.
3. Gula – Goddess of death and healing - Patroness of the physician - Great lady of
physicians
3 Main Medical Practitioners:
1. Asu – physician priest
2. Ashipu – exorcist and incantation priest
3. Baru – the seer priest They believe that disease is a consequence of a SIN. Cures
therefore should involve spiritual religious purification and catharsis.
LIBRARY OF NINEVEH
- The greatest contribution of Mesopotamian in the profession of Pharmacy.
- It holds 32,000 clay tablets
- Collected by Assyrian King Asshurbanipal in 17th century BC
- 250 drugs of vegetable origin
- 120 of mineral origin
- 180 from other sources.
ANCIENT EGYPT
Ancient Egyptians believed that a sick person was one out of harmony with the world,
having irked the gods, the dead or the spirits. The logical way to restore harmony was by
religious and magical means.
DEITIES:
- Thoth, the inventor of science and medicine and patron of physicians,
- Imhotep, a mortal of the third millennium BC who was deified in Egypt during Greco-Roman
times.
PAPYRUS EBERS
- Most important pharmaceutical record is the
"Papyrus Ebers" (1500 B.C.),
- It is a collection of 800 prescriptions, mentioning 700 drugs.
- The Ebers Papyrus, also known as Papyrus Ebers, is an
Egyptian Medical papyrus of herbal knowledge dating
to c. 1550 BC.
- George Ebers -Among the oldest and most important
medical papyri of Ancient egypt, it was purchased at Luxor
(Thebes) in the winter of 1873–74 by Georg Ebers. It is currently
kept at the library of the University of Leipzig, in Germany.
ANCIENT CHINA
– Legendary Emperor Shen-nung was credited as the father of pharmaceutics by the scholar-
ruler Liu An in the second century BC.
– Pen-ts’ao which was translated as “material medica”, “fundamentals of simples”, and “the
botanical basis of pharmacy”.
ANCIENT GREECE
– The civilization developed by the Hellenes was individualistic,
speculative, this-worldly, and concerned with the concepts of
liberty and aesthetics—and Greek medicine and pharmacy
developed within this cultural framework.
– The momentous achievement of Greek medic ine was it seeking a
natural basis for disease, its causes and its treatment.
– Greek Physicians: Prepared their own medicines and left
prescription behind for family members to compound and
administer
– Theophrastus (about 300 B.C.)- The greatest early Greek
philosophers and natural scientists, is called the "father of botany."
His botanical works, De Historia Plantarum and De causis
plantarum
MIDDLE AGES (400AD- 1453)
A period from Fall of Rome to Fall of Constantinople. The following are the persons with important
contribution to the discovery of Pharmacy profession:
CLADIUS GALEN
– A prominent Greek physician, surgeon and philosopher in the Roman empire. His
principles of preparing and compounding medicines ruled in the Western world for 1,500
years; and his name still is associated with that class of pharmaceuticals compounded by
mechanical means - galenicals. He was the originator of the formula for a cold cream,
essentially similar to that known today.
– Three remedies that were to become universally celebrated and esteemed, although they
were not original with him, 1. hiera picra 2. terra sigillata 3. theriaca (theriac).
- Hiera picra- It is the oldest pharmaceutical compound in existence. Galen’s formula
called for aloes, to which spices and other herbs were added and with the addition of
honey.
- Terra sigillata or sealed earth was a greasy clay. It was formed into large, tablet-like
units upon which the seal of the place origin was impressed. It was used as an
antidote for poisons, dysenteries, fevers and other illnesses.
- Theriaca- It is also known as treacle, was the pharmaceutical par excellence.
Contained varying number of ingredients, sometimes more than seventy. Contents
were largely herbal, opium playing a prominent role, castoreum, viper flesh and
skink. Intended as an antidote to the bites of wild creatures, it eventually became a
universal antidote for poisons and remedies used in many illnesses.
Rhazes (860-932) & Avicenna (980- 1063) - They added to the writings of Greek . Rejected
the old idea that foul tasting worked best in medicine. They developed and exerted effort in
their dosage forms elegant and palatable through silvering of pills and use of syrups.
King Frederick II of Sicily, King of Jerusalem, King of Germany & Italy & Holy Roman Empire.
In mid 13th century (1240) Frederick II codified the separate practice of pharmacy from
medicine.
MODERN EUROPE
Discovery of vaccine
– Pasteur discovered 3 vaccines; for fowl cholera (1881), anthrax (1881) and rabies (1885).
Emil Von Behring diphtheria antitoxin
– The term vaccine is in honor of the test animal used in his experiment which is a female
cattle (Italian: Vacca)
Salvarsan (1910)
– Paul Ehrlich’s Salvarsan in 1910- first discovered
chemotherapeutic agents. Introduced the “selective
toxicity” principle. He also discovered Salvarsan.
– Salvarsan is also known as Magic Bullet and Compound
606. It is a drug used for syphilis.
– It is a bacterial infection usually spread by sexual contact.
The disease starts as a painless sore — typically on your
genitals, rectum or mouth. Syphilis spreads from person to
person via skin or mucous membrane contact with these
sores.
– Pharmacists were not a loss for work as the number of prescriptions grew, or new effective
drugs came into the market. Chain drug stores displacing independent corner drug stores
especially in urban areas.
– Laws regulating the production of drugs and pharmacy were modernized.
– BS Pharmacy was extended to 5 years and curriculum continued to emphasize physical
sciences which underlie the making of medicines.
PHARMACY IN USA
Community Pharmacy
APOTECHARY IN USA
– Apothecary shops first appeared in Boston, New York
and Philadelphia. Christopher Marshall, Irish immigrant,
developed a pioneer pharmaceutical enterprise.
– Marshall Apothecary in Philadelphia - This was a
leading retail pharmacy, large-scale chemical
manufacturer, a place for training pharmacists, and an
important supply depot during the American Revolution.
Most of the early American apothecaries sold various
items including crude drugs, chemicals, imported
nostrums (secret cures), spices, teas, and coffees
America’s first Association of Pharmacists.
– The Philadelphia College of Pharmacy. It was founded in 1821 at Carpenter’s Hall, same
place were the Declaration of Independence of USA was announced.
William Proctor Jr.
– He is the Father of American Pharmacy. American Pharmaceutical Association (APhA)
began in 1852. It was started to improve communication among pharmacists, to develop
standards for education and apprenticeship, and to improve the quality control of imported
drugs.
From early 1900 through the early 1940s druggists continued to compound and prepare medicines
for patients. Drug manufacturers were starting to discover the active ingredients of various
products derived from nature.
Jack Eckerd
– Gradually, medicines were made with active ingredients and made available for druggists to
dispense directly to patients. Shortly, after World War II (1945) a young entrepreneur from
Erie, Pennsylvania, named Jack Eckerd made his mark by starting self- service in the
pharmacy.
Mythical period
– Katalonan or Babaylan, a woman mystic who is "a specialist in the fields of culture, religion,
medicine and all kinds of theoretical knowledge about the phenomenon of nature.
Superstitious period
– Ancient Filipino believed that diseases are caused by spiritual or elemental forces.
– Examples: Mambabarang, Aswang, Nuno
Empirical period
– Pre – Spanished era there were herbolarios. These are skilled men in the use of healing
herbs. Heals people using herbs and traditional practices such as hilot or massage.
SPANISH ERA
– Fr. Fernando Santa Maria (1704-1774) Dominican priest, native of madrid “ Medicinas
Caseras” 1st ed. 1786 – contained suggestions for treatment of certain diseases. 3 Topics
of the book: 1. Medicinal barks and herbs 2. Various sickness 3. Various secrets and rarities
worth knowing.
– Fr. Blanco,OSA- and his botanical masterpiece “Flora de Filipinas”
REFERENCES:
◉ Pharmacy: An introduction to the Profession, 2nd edition by Posey, L. Michael
◉ Remington : The Science & Practice of Pharmacy 21st edition by Genaro Alfonso
◉ Pharmacy by Cowen D. and Helfand W.
TOPIC 2:
SCOPE OF PHARMACY PRACTICE &
ESSENTIAL FUNCTIONS
EXPECTED OUTCOMES:
At the end of this unit, the students are expected to:
◉ Describe the scope of Pharmacy practice according to the Philippine Pharmacy Act
◉ Identify the essential functions of Pharmacists
◉ Describe the current and emerging fields of Pharmacy
CHECKLIST:
◉ Read course and unit objectives
◉ Read study guide prior to class attendance
◉ Read required learning resources; refer to unit terminologies for jargons
◉ Proactively participate in discussions
◉ Participate in weekly discussion board (Canvas)
◉ Answer and submit course unit tasks
TOPIC 2: SCOPE AND FUNCTIONS OF
PHARMACY PRACTICE
– Pharmacy is the art and science of preparing and dispensing medications and the provision
of drug-related information to the public.
It involves the following:
– interpretation of prescription orders
– compounding, labeling, and dispensing of drugs and devices
– drug product selection and drug utilization reviews;
– patient monitoring and intervention;
– and the provision of cognitive services related to use of medications and devices.
Pharmacists
– are those who are educated and licensed to dispense drugs and to provide drug
information—they are experts on medications.
– They are the most accessible member of today’s health care team, and often are the first
source of assistance and advice on many common ailments and health care matters.
DEFINITION OF TERMS
COMPOUNDING Is the preparation, mixing, assembling,
packaging or labeling of a drug as the result
of a prescription or drug order by a
physician, dentist, optometrist or
veterinarian or for the purpose of research,
teaching or chemical analysis and not for
sale or dispensing
Pharmaceutical care
– It is the responsible provision of drug therapy for the purpose of achieving definite
outcomes that improve a patient’s quality of life.
– Hepler and Strand coined the term in 1990.
A. PROFESSIONAL FUNCTIONS
– Ensuring safe and effective use of drugs by patients.
– Participating in the practice of drug use decision
– Selecting the drug product dosage form
– Selecting drug product source of supply
– Determining the dose and dosage schedule
– Preparing the drug product for patient’s use
– Dispensing the drug with proper instruction
– Providing drug information to the patient
– Monitoring the patient to maximize compliance
– Monitoring the patient to detect adverse drug reactions and interactions.
– Monitoring the patient to enhance the outcomes of drug therapy
– Counseling patient on the appropriate utilization of medication
B. TECHNICAL FUNCTIONS
– Include a large variety of manipulative or mechanical tasks that must be carried out
during the course of practice.
1. Functions indirectly related to dispensing.
Example:
- Stocking shelves,
- cleaning up after the pharmacists has prepared the drug.
2. Functions carried out as a prerequisite to dispensing.
Example: Repacking multiple and unit dose packages of drugs and their labeling
3. Functions directly involved with dispensing.
Example:
- Counting or dispensing prefabricated medications,
- Reconstituting drug powders
- Preparing labels
– Medication therapy
– Research and development
– Clinical pharmacy- is a health science discipline in which
pharmacists provide patient care that optimizes medication therapy
and promotes health, and disease prevention.
– Academe
– Quality control
– Legal and regulatory practice
– Public health- is the science of protecting and improving the
health of people and their communities. This work is achieved by
promoting healthy lifestyles
– Pharmaceutical journalism
– Pharmacy informaticists- The scientific field that focuses on
medication-related data and knowledge within the continuum of
healthcare systems—including its acquisition, storage, analysis,
use and dissemination—in the delivery of optimal medication-
related patient care and health outcomes
REFERENCES:
◉ Pharmacy: An introduction to the Profession, 2nd edition by Posey, L. Michael
◉ Remington : The Science & Practice of Pharmacy 21st edition by Genaro Alfonso
◉ Pharmacy by Cowen D. and Helfand W.
TOPIC 3:
ATTRIBUTES OF PHARMACISTS
EXPECTED OUTCOMES:
At the end of this unit, the students are expected to:
◉ Discuss the importance of Pharmacists in the Healthcare team.
◉ Describe the attributes using the World Health Organization’s Seven Star Pharmacists.
REQUIRED READINGS
CHECKLIST:
◉ Read course and unit objectives
◉ Read study guide prior to class attendance
◉ Read required learning resources; refer to unit terminologies for jargons
◉ Proactively participate in discussions
◉ Participate in weekly discussion board (Canvas)
◉ Answer and submit course unit tasks
TOPIC 3: ATTRIBUTES OF PHARMACISTS
1. CAREGIVER
– Pharmacists must provide caring services of the highest
quality, and must view their practice as integrated and
continuous with those of the health care system and other
health professionals
2. DECISION MAKER
– The foundation of the pharmacist’s work must revolve around accurate decisions made or
taken regarding appropriate, efficacious, safe, and cost-effective use of resources (e.g.,
personnel, medicines, chemicals, equipment, procedures, and practices).
– Pharmacists must also play a pivotal role in setting medicines policy both at the local and
national levels. The pharmacist must thus, possess the ability to evaluate, synthesize data and
information, and decide upon the most appropriate course of action
3. COMMUNICATOR
– The pharmacist must provide a link between physicians and patient, and to other health care
professionals.
– He or she should have complete knowledge about all the pharmaceuticals with recent updates
and be confident, while communicating with other health care professional and community
member.
– Pharmacists must have effective patient communication skills and it may help him/her to
provide better pharmaceutical care to the community by identifying the patient’s problem and
requirements, ensuring the quality of patient life.
4. MANAGER
– Pharmacists must have the ability to manage the natural and commercial resources which
include man power, physical and financial resources.
– Developing and maintaining department policies and procedures, goals, objectives, quality
assurance programs, safety, and environmental and infection control standards are key
components that aid the pharmacist in evolving as an efficient manager as well.
5. LIFE-LONG LEARNER
– The concepts of life-long learning must begin, while attending pharmacy school and must be
supported throughout the pharmacist’s career.
– Pharmacists regularly update their knowledge and skills in order to keep up with the current
trends in issues-related to drug therapy management.
– Continuing Professional Development- The Accreditation Council for Pharmacy Education
defines Continuing Professional Development as “the lifelong process of active participation in
learning activities that assists individuals in developing and maintaining continuing competence,
enhancing their professional practice, and supporting achievement of their career goals.”
6. TEACHER
– One of the pharmacist’s responsibilities is to assist with the education and training of future
generations of pharmacists and the general public.
– The dynamic fashion of pharmacy teaching is not only to
import the skill and knowledge to others; it also offers an
opportunity for professionals to gain new knowledge and
to fine-tune existing skills.
7. LEADER
– The pharmacist also plays a leadership role in the healthcare system to make decisions,
communicate, and manage effectively.
– A leader is one who can create an idea/vision and motivate others team members to achieve
the vision. A leader is a person who continually encourages constructive differences.
– A leader is mission-driven without being egocentric. Effective pharmacy leaders are experts in
demonstrating and creating high-performance
– pharmacy practices characterized by the high-quality patient care, improved medication safety,
and maximum productivity.
REFERENCES:
◉ Pharmacy: An introduction to the Profession, 2nd edition by Posey, L. Michael
◉ Remington : The Science & Practice of Pharmacy 21st edition by Genaro Alfonso
◉ Pharmacy by Cowen D. and Helfand W.
◉ Seven Star Pharmacists Concept by World Health Organization
UNIT 2
REGULATIONS OF THE PHARMACY IN THE PHILIPPINES
EDUCATIONS & TRAINING
LAWS & ETHICS AFFECTING PHARMACY PRACTICE
PHILIPPINE PRACTICE STANDARDS FOR PHARMACISTS
PHARMACY ORGANIZATIONS
TOPIC 4:
EDUCATION & TRAINING OF PHARMACISTS
EXPECTED OUTCOMES:
At the end of this unit, the students are expected to:
◉ Demonstrate understanding of education and trainings of Pharmacists.
◉ Describe the attributes using the World Health Organization’s Seven Star Pharmacists.
REQUIRED READINGS
CHECKLIST:
◉ Read course and unit objectives
◉ Read study guide prior to class attendance
◉ Read required learning resources; refer to unit terminologies for jargons
◉ Proactively participate in discussions
◉ Participate in weekly discussion board (Canvas)
◉ Answer and submit course unit tasks
TOPIC 4: EDUCATIONS & TRAINING OF
PHARMACISTS
NOTES: PHARMACY EDUCATION
Pharmacy Education is a four year-Bachelor’s Degree which provides a broad spectrum of
scientific training and can lead to employment in a wider range of scientific fields principally in
higher education institutions, community drug stores, hospitals, in government agencies, research
establishments, public health and pharmaceutical industry.
– policies and standards are adopted and promulgated by the Commission
– a four year Bachelor's Degree
– provides a broad spectrum of scientific training
– can lead to employment in a wider range of scientific fields
Can be employed in:
- higher education
- institutions - in government agencies
- community drug stores - research establishments,
- hospitals - public health pharmaceutical industry
It should also encompass:
- pharmaceuticals
- cosmetics
- household hazardous substances
- drug delivery services, and veterinary medicines
Main concern of Pharmacy Education
– to provide the country with pharmacists who are scientifically competent
Pursuant to the Philippine Pharmacy Act, after graduation a person must take and pass the
Pharmacist Licensure Examination administered by the Board of Pharmacy before
practicing the profession.
The following are the qualifications for taking the Licensure Examination:
– (a) He must be a citizen of the Philippines/ Foreign reciprocity (RA 10918)
– (b) He must be of good moral character
– (c) He must have completed an internship program of at least 960 hours
– (d) He must have graduated with the degree Bachelor of Science in Pharmacy from an
accredited school.
Foreign reciprocity- Unless the country or state of which the foreign pharmacist is a subject or
citizen, specifically permits Filipino pharmacists to practice within its territorial limits on the same
basis as the subjects or citizens of the said foreign country or state under reciprocity and under
international" agreement, no foreigners shall be admitted to licensure examinations, given a
COR to practice as pharmacist nor be entitled to any of the privileges under RA 10918.
– The Pharmacist Licensure Exam is composed of 6 Modules:
o Module 1- Pharmaceutical Chemistry
o Module 2- Pharmacognosy & Biochemistry
o Module 3- Practice of Pharmacy
o Module 4- Pharmacology & Pharmacokinetics
o Module 5- Pharmaceutics
o Module 6- Quality Assurance & Quality Control
– Must obtain 75% with no rating lower than 50% in any modules
– Failure for the 3rd time= refresher course (Pre board review course)
Importance:
1. prove they are capable of adhering to current essential standards
2. helps people retain a consistent set of high quality, relevant skills and knowledge
throughout their professional life.
3. demonstrate new knowledge, work to impressive standards, and progress in their
career.
TYPES OF CPD
The learner engages in interactive, participation-based
learning, usually provided by somewhere other than the
Formal CPD: company for which they work. Structured CPD often
structured, active involves more than one learner for the benefit of idea
learning sharing and group activities, but it can be one-to-one.
Structured CPD includes:
• Online and offline training courses.
• Learning-oriented conferences and meetings.
• Group events.
• Workshops.
Self-directed learning refers to any development activities
that are guided solely by the learner, often without
following a curriculum. If you are going to engage in self-
directed CPD, you should draw up a CPD plan that covers
Informal CPD: what you expect to learn.
unstructured, self- Self-directed CPD includes:
directed learning • Studying online and offline publications written by
industry experts.
• Reading articles and case studies.
• Listening to and making notes on podcasts.
• Following industry-specific news feeds.
• Writing articles and essays for personal
development.
• Additional studying and revising for professional
examinations.
REFERENCES:
◉ Republic Act 10918
◉ Republic ACT 7722
◉ CHED Memorandum Order No. 9
◉ Mims. (n.d.). Pharmacists: Here are your options for postgraduate studies. Retrieved July
25, 2020, from https://today.mims.com/pharmacists--here-are-your-options-for-
postgraduate-studies
◉ Koshman, S., & Blais, J. (2011, March). What is Pharmacy Research? Retrieved July 25,
2020, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093426/
TOPIC 5:
LAWS & ETHICS AFFECTING PHARMACY
PRACTICE
EXPECTED OUTCOMES:
At the end of this unit, the students are expected to:
◉ Identify the different laws governing Pharmacy practice.
◉ Demonstrate understanding of provisions of laws and to apply it to actual setting.
◉ Describe the Philippine Practice Standards for Pharmacists and Code of Ethics for
Pharmacists.
REQUIRED READINGS
CHECKLIST:
◉ Read course and unit objectives
◉ Read study guide prior to class attendance
◉ Read required learning resources; refer to unit terminologies for jargons
◉ Proactively participate in discussions
◉ Participate in weekly discussion board (Canvas)
◉ Answer and submit course unit tasks
TOPIC 5: LAWS & ETHICS AFFECTING
PHARMACY PRACTICE
– The practice of pharmacy is regulated by the law of the country. To practice pharmacy, a
pharmacist must be a registered pharmacist (RPh) in that country. Administration of
pharmacy laws and the granting of registration to practice pharmacy are authorities vested
in the Board of Pharmacy.
– The following laws govern the practice of pharmacy profession and relative to drugs in the
Philippines.
R.A. No. 10918 - The Pharmacy Act
R.A. No. 3720 - The Food, Drug and Cosmetics Act
R. A. No. 9165 - The Dangerous Drug Act of 2002
R.A. No. 6675 - The Generics Law of 1988
R.A. No. 8203- The Special Law on Counterfeit Drugs
R.A. No. 9994- The Senior Citizen Act
R.A. No. 7394- The Consumer Act of the Philippines
– An act regulating the practice of pharmacy in the Philippines, repealing for the purpose RA
5921
– Signed by Pres. Benigno S. Aquino III
– Approved on July 21, 2016
– Enforcement: Professional Regulatory Board of Pharmacy
– An act to ensure the safety and purity of foods and cosmetics, and the purity, safety,
efficacy and quality of drugs and devices being made available to the public
– Approved on June 22, 1963
– Amended by EO 175 on May 22 1987 (Its original title is Food, Drugs & Cosmetics Act.
There is no provision about medical devices prior to amendment)
– Enforcement: Food and Drug (FDA) Philippines
ADULTERATED MISBRANDED
It can cause harm when consumed by If it can confusion or it is misleading to
humans. the consumers.
– contains any poisonous or deleterious – If its labeling and container is false or
– consists of decomposed substance misleading
– prepared under unsanitary conditions – if it is offered for sale under the name
(doesn’t conform to CGMP) of another product
– container contains poisonous – If the product is counterfeit (fake)
substance – Required information in the label is not
– contains coal tar (a coloring agent that present (ex. Adverse effect, possible
is banned due to its toxic effect) allergic reactions)
THE GENERICS ACT (RA 6675)
GENERIC NAME
– It is also known as Non-Proprietary Name
– simpler term for scientifically recognized AI of the drug
– Using GN can reduce the cost of treatment by reducing the promotions and advertising cost
associated with branded products.
PRESCRIBING ERRORS
1. Violative Prescription
– Generic name is not written
– Generic name is illegible but brand name is legible
– Both are written but with word “NO SUBSTITUTION”
What to do?
– Shall not be filled
– Kept and reported to DOH
– Advise patient to get proper Rx
2. Erroneous Prescription
– Brand name precedes generic name
– Generic is in parenthesis
– Brand is not in parenthesis
What to do?
– Shall be filled
– Kept and reported to DOH
3. Impossible Prescription
– Only generic is written but not legible
– Generic name does not match with brand name
– Both written – both illegible
– Drug is not registered with DOH
What to do?
– Shall not be filled
– Kept and reported to DOH
– Advise patient to get proper Rx
Declaration of Principles:
– Provide efficient service in compounding and filling of prescriptions and the dispensing
of drugs, chemicals, and medicines
– Special knowledge, skill, and integrity are demanded on the part of those engaged in
Pharmacy
o Ex. An old lady asking you what would be the side effects of taking paracetamol at
its exceeding dose and what must be done to overcome this side effects. This is an
example of special knowledge because not all professional know what could be the
possible side effects and the antidote for its toxicity
– Pharmacists should pursue a prescribed course of study and should pass a professional
examination.
– Qualified pharmacists have a full recognition of their responsibility for the preservation of
public health.
– The pharmacist should therefore ever bear in mind that he is more than a merchant. (We
are not “glorified merchant” we are an integral part of the health care team giving drug
information to the public.)
DUTIES OF PHARMACISTS
– They should refrain the use of substitutes or drugs of substandard strength.
They should maintain all standards established by Pharmacopeia and
National Formulary.
– No drugs should be dispensed with inferior quality, injurious or of no
effect to the patient.
– Poisonous substances must only be dispensed to a qualified persons
PUBLIC except: elderly, children and mentally ill
– Pharmacists should follow laws involving dispensing of narcotics and
abortives
§ Narcotics- drugs that induces sleep
§ Abortives- drug that can induced labor
– The pharmacist should endeavor to gain the confidence of customers by
attending promptly to their wants.
– The pharmacist is entitled to just and fair compensation (Professional Fee).
What they are paying to you reflects your services offered to them.
– Pharmacist should be concerned about the health and safety of his
customer
– Pharmacist should keep his establishment clean, neat and sanitary
– There should be no secret agreement with a physician to share with him his
profits in prescriptions.
– The pharmacist should be a good citizen and should uphold and defend
the laws of the land.
REFERENCES:
◉ Pharmacy: An introduction to the Profession, 2nd edition by Posey, L. Michael
◉ Remington : The Science & Practice of Pharmacy 21st edition by Genaro Alfonso
◉ Limuaco, O.M. (2009). Pharmaceutical Jurisprudence and Ethics 6th ed. Manila: Centro
Escolar University
TOPIC 6:
PHILIPPINE PRACTICE STANDARDS FOR
PHARMACISTS
EXPECTED OUTCOMES:
At the end of this unit, the students are expected to:
◉ Demonstrate knowledge on the Philippine Practice Standards for Pharmacists
◉ Demonstrate the expected competencies of Filipino Pharmacists
◉ Demonstrate the desirable traits of Filipino pharmacists in providing patient care.
CHECKLIST:
◉ Read course and unit objectives
◉ Read study guide prior to class attendance
◉ Read required learning resources; refer to unit terminologies for jargons
◉ Proactively participate in discussions
◉ Participate in weekly discussion board (Canvas)
◉ Answer and submit course unit tasks
TOPIC 6: PHILIPPINE PRACTICE STANDARDS
FOR PHARMACISTS
– This is to guide, advise and provide reference to Filipino pharmacists on how they can
best fulfill their duties and responsibilities as health professionals.
This includes:
– Competency Standards: Specific functions to be carried out by a
pharmacist who is deemed professionally qualified
REFERENCES:
◉ Pharmacy: An introduction to the Profession, 2nd edition by Posey, L. Michael
◉ Remington : The Science & Practice of Pharmacy 21st edition by Genaro Alfonso
◉ Philippine Practice Standards for Pharmacists (PPHA)
TOPIC 7:
PROFESSIONAL PHARMACY
ORGANIZATION (Local & International)
EXPECTED OUTCOMES:
At the end of this unit, the students are expected to:
◉ Discuss the different Pharmaceutical Organizations
◉ Differentiate the functions and objectives of the Pharmaceutical Organizations.
CHECKLIST:
◉ Read course and unit objectives
◉ Read study guide prior to class attendance
◉ Read required learning resources; refer to unit terminologies for jargons
◉ Proactively participate in discussions
◉ Participate in weekly discussion board (Canvas)
◉ Answer and submit course unit tasks
TOPIC 7: PROFESSIONAL PHARMACY
ORGANIZATIONS
– When the practicing pharmacists grew in number, they saw the need to form societies
and organizations to bind themselves towards attaining the same goal and objectives for
the upliftment of pharmacy as a profession and to improve the pharmacy services in the
delivery of better patient care.
– The different organizations were established on international, national, and local levels.
Some organized themselves based on their field of specialization.
INTERNATIONAL ORGANIZATIONS
NATIONAL ORGANIZATION
PPhA (PHILIPPINE PHARMACISTS ASSOCIATION)
– Founded in 1920.It is national profession organization of pharmacists
in the Philippines.
– Considered as the main organization with which other associations of
pharmacists and pharmacy students are affiliated.
– Official Newsletter: THE HYGEIAN
Main objectives:
1. To encourage to study pharmacy
2. To foster research in Philippine medicinal plants
3. Stimulate scientific investigations
4. To improve close relationship among pharmacist.
5. To improve local market for drugs, chemicals and pharmaceutical manufacturing in the
Philippines
OTHER ORGANIZATIONS OF PHARMACY IN
THE PHILIPPINES
Pharmacy Organizations
PACOP It is an association of duly government-recognized colleges of
Philippine Association of pharmacy in the Philippines represented by their deans who are the
Colleges of Pharmacy regular members.
1) Associate members - licensed pharmacists who are faculty
members of duly recognized colleges of pharmacy
2) Auxiliary members - pharmacy students
REFERENCES:
◉ Pharmacy: An introduction to the Profession, 2nd edition by Posey, L. Michael
◉ Remington : The Science & Practice of Pharmacy 21st edition by Genaro Alfonso
◉ Pharmacy by Cowen D. and Helfand W.
UNIT 3
DIFFERENT ROLES OF PHARMACISTS
PHARMACISTS IN DIFFERENT AREAS OF PRACTICE
DOSAGE FORMS
THERAPEUTIC CATEGORY OF DRUGS
TOPIC 8:
AREAS OF PHARMACY PRACTICE
EXPECTED OUTCOMES:
At the end of this unit, the students are expected to:
◉ Demonstrate Familiarization of the Roles of Pharmacists in Selected Areas of Practice
◉ Familiarize on the different areas of practice in which they become interested.
CHECKLIST:
◉ Read course and unit objectives
◉ Read study guide prior to class attendance
◉ Read required learning resources; refer to unit terminologies for jargons
◉ Proactively participate in discussions
◉ Participate in weekly discussion board (Canvas)
◉ Answer and submit course unit tasks
TOPIC 8: AREAS OF PHARMACY PRACTICE
COMMUNITY PHARMACISTS
– They are also known as Retail Pharmacist
– A community pharmacist is a professional in his own right, a partner in the health team
who handles drugs of great potency and value, manufactured by a highly sophisticated
industry.
– The pharmacist may establish her own drugstore or be employed in an existing drugstore or
chain drugstore.
– It is practiced by about 85% of pharmacy graduates who make a unique hybrid of
businessmen and professionals
A Community Pharmacists must:
– have good people and communication skills.
– be comfortable having a high level of interaction with the general public.
– be able to manage significant paperwork and logistical details related to health insurance
issues to make sure patients get the right care at the right price.
Responsibilities:
– Work with customers to fill their prescriptions, explain proper medication
use, and provide clinical services.
– They are often asked to give advice on diet, exercise, wellness or stress
management. They also advise doctors about medication
– Interpretation of prescription & dispensing of pharmaceutical
preparations
– Compounding of medications based on Prescription
– Give appropriate Patient counselling
– Pharmacy administration (inventory, ordering, receiving, returning of
merchandise etc.)
– Monitor the sales and performance of the drugstore
– Regularly attends Seminars & Continuing Professional Development
HOSPITAL PHARMACIST
Responsibilities:
– Provide and Evaluate Pharmaceutical services
– Draw a plan for hospital pharmacy administration
– Liaison between administrative authorities and medical Doctors.
– Enforce the policies and procedures for the recruitment of adequate and competent staff
– Develop and maintain an effective system
– Participate in and adhere to the financial plan of the operation for the hospital
– The Chief Pharmacist in the Hospital serves as the secretary of the Pharmacy
Therapeutics Committee (PTC).
CLINICAL PHARMACIST
B. Production Pharmacists
– where a pharmacist can work as staff or be given a supervisory position.
– Basically, they are liable in the total production of drugs from: Procurement of the raw
materials – Weighting Mixing – Assay – Packaging – Dispensing
– Production pharmacist should have the skills and knowledge in operating the different
machineries that is use in the production.
– They are also liable in maintaining the cleanliness of the manufacturing rooms before and
after the production.
D. R&D Pharmacists
– Research and development (often called R&D) is regarded as the backbone of the
pharmaceutical industry.
– A pharmacist can work as a researcher
– In addition to research, they are also responsible for making sure that drug labeling is
accurate and meets the requirements of state and federal laws.
Pharmaceutical researchers use their scientific knowledge to help:
• develop new medications
• test new substances
• evaluate existing products
• and create new dosage forms.
E. Company Pharmacists
– Regulators or Regulatory Pharmacists.
– The pharmacist works as a liaison of a company to FDA and in charge of the registration
of company products.
WHOLESALE PHARMACIST
PHARMACY ACADEME
– Pharmacy academe offers excellent opportunities for pharmacists with advanced degrees
in any of the professional specialties.
– Expanding enrolment in colleges to meet the manpower needs of the future offers excellent
opportunities for careers in college teaching.
– Academic pharmacists have many key responsibilities, including training future
pharmacists and conducting research.
– A Pharmacist must consider obtaining advanced degrees, certification, and residencies
before being part of the academe.
TOPIC 9:
DRUG DOSAGE FORMS
EXPECTED OUTCOMES:
At the end of this unit, the students are expected to:
◉ Describe the different drug dosage forms.
◉ Determine the different routes of administration of drugs.
CHECKLIST:
◉ Read course and unit objectives
◉ Read study guide prior to class attendance
◉ Read required learning resources; refer to unit terminologies for jargons
◉ Proactively participate in discussions
◉ Participate in weekly discussion board (Canvas)
◉ Answer and submit course unit tasks
TOPIC 9: DRUG DOSAGE FORMS
NOTES: DRUGS
– Drugs may be defined as an agent or substance, intended for use in the diagnosis,
mitigation, treatment, cure or prevention of disease in human beings or animals.
– Drugs are rarely administered in their original or crude forms.
– They are administered in different dosage forms by converting them into suitable
formulations.
DOSAGE FORMS
– Dosage forms are the carrier through which drug molecules are delivered to sites of action
within the body. Every dosage form are a combination of the drug and different kinds of
non – drug components called as Excipients or additives.
– The additives are used to give a particular shape to the formulation, to increase stability,
palatability & more elegance to preparations.
Snuffs
- These are finely divided solid dosage forms of medicaments
which are inhaled into nostrils.
EFFERVESCENT - It improves palatability of the drug.
GRANULES - Effervescent granules are meant for internal use.
- They contained medicaments mixed with citric acid, tartaric
acid & sodium bicarbonates, sometime saccharin or
sucrose may be added for sweetening taste
TABLETS
These are solid dosage forms of medicaments which are prepared by molding or by compression
with or without excipients
– Compressed tablets- Classical - No special coating
– Multiple compressed- Layered tablets - More than one
compression
– Chewable tablets- Meant to be chewed and subsequently
swallowed - For children, elderly, and patients who cannot swallow
– Buccal- designed to be absorbed in the buccal cavity
– Sublingual- designed to be absorbed under the tongue
– Effervescent- release carbon dioxide when dissolved in water
– Sugar coated- mask offensive taste - disadvantage: bulky - less bulky,
– Film coated-less time consuming and more durable
– Enteric coated- designed to dissolve in alkaline ph to release medication in the small
intestine
CAPSULES
are solid unit dosage forms in which one or more medicaments enclosed within a shell. Capsules
mainly divided in to two parts namely as:
1. Body (Longest part of capsule shell)
2. Cap (Smallest part of capsule shell).
SOLUTIONS
(Monophasic Liquid Dosage Form)
– These are liquid preparations, that contain one or more chemical substances dissolved in a
suitable solvent or mixture of mutually miscible solvents.
– The component of the solution which is present in a large quantity is known as “solvent”
and the component present in small quantity is termed as “solute”
Advantages:
– Easy to swallow
– Can be used by any route of administration
– Easy to adjust the dose.
NON-STERILE SOLUTIONS
Intended to be swallowed orally or applied topically.
1. SYRUPS
– solutions containing high concentration of sucrose or other sugars examples: cherry syrup
(47% cherry juice), cocoa syrup, orange syrup, raspberry syrup.
– Syrup, NF (simple syrup) - nearly saturated aqueous solution of sucrose (85% w/v) -
inherently stable and resistant to the growth of microorganisms when properly prepared and
maintained.
– It prevents decomposition of many vegetable substance because it can cause high osmotic
pressure which prevent the growth of bacteria.
– They are palatable due sweet taste.
– Uses: Sweetening agent & Preservative
2. ELIXIRS
– are clear, pleasantly flavoured, sweetened hydroalcoholic solutions intended for oral use
alcohol content: 5-40%, but most of the time, varies widely
– Use: Flavorant
– Example: Aromatic Elixir, NF 22% alcohol
3. SPIRITS
– Also known as Essences
– are alcoholic or hydroalcoholic solutions of volatile substances
– Generally, it contains over 60% alcohol
– Uses: flavoring agents, vehicle
4. TINCTURES
– are alcoholic or hydroalcoholic solutions prepared from vegetable materials or from
chemical substances
– alcohol content: 15-80%
– Examples: Iodine Tincture; Opium Tincture (also known as Laudanum)
5. FLUIDEXTRACTS
– are liquid preparations of vegetable drugs containing alcohol as solvent, preservative or
both and so made that unless otherwise specified in an individual monograph
– Each mL contains 1 g of the standard drug.
6. AROMATIC WATERS
– Also known as medicated waters
– are clear, aqueous solutions saturated with volatile oils or other aromatic or volatile
substances
– Uses: flavored vehicle for water soluble drugs -aqueous phase in some emulsions or
suspensions
7. GARGLES
– are aqueous solutions used for treating the pharynx and nasopharynx by forcing air from the
lungs through the gargle which is held in the throat.
– Uses: antiseptic, antibiotic and anesthetic
8. MOUTHWASHES
– are aqueous solutions used for its deodorant, refreshing or antiseptic effect or for control of
plaque in the oral mucosa.
9. TOPICAL SOLUTIONS
– Intended for topical application to the skin or mucous membranes
TOPICAL SOLUTIONS
SPRAYS • are aqueous or oleaginous solutions in the form of
coarse droplets or finely divided solids to be applied
topically, most usually to the nasopharyngeal tract
or to the skin
TOPICAL ANTI-INFECTIVE
• kill microorganisms when applied to the skin or
mucus membranes
• Povidone-iodine, thimerosal, and hydrogen peroxide
topical solutions
10. ENEMAS
– Rectal solutions employed to evacuate the bowel (evacuation enemas), influence the
general system by absorption- Sodium phosphates enema
– (retention enemas) or to affect locally the site of disease - Hydrocortisone enema,
aminophylline enema
11. DOUCHES
– Are aqueous solutions directed against a part or into a cavity of the body
– It functions as a cleansing or antiseptic agent -are frequently dispensed in the form of a
powder with the directions for dissolving in a specified quantity of warm water
12. LINIMENTS
– Also known as embrocations - are nonaqueous alcoholic or oleaginous solutions (or
emulsions) of various medicinal substances
– intended to be rubbed on the skin – rubefacient (causes redness of the skin), counterirritant
or penetrating action
13. COLLODIONS
– are liquid preparations composed of pyroxylin dissolved in a nonaqueous solvent mixture
usually composed of alcohol and ether, with or without added medicinal substances.
– Pyroxylin- Also known as soluble gun cotton. Produced though the action of nitric acid and
sulfuric acid on purified cotton.
– Flexible collodion - prepared by the addition of castor oil (3%) (for flexibility) and camphor
(for water-proofing) (2%) to collodion.
STERILE SOLUTION
– These are solutions free from pathogenic (disease-causing) microorganisms
– It is administered in the mucus membranes (eyes, ears, nose) or parenterally (injection)
– They are rendered isotonic- solutions that have the same osmotic pressure compare to
body fluids to prevent irritation.
1. Nasal Solution
- are aqueous solutions designed to be administered to the nasal passages in drops or
sprays -vehicle used is usually water, but a co-solvent system may be used -may
contain preservatives, buffer, antioxidant, surfactant.
4. Irrigating solution
- sterile solutions used to wash or bathe surgical incisions, wounds or body tissues -
should be labeled “Not for Injection” and “For Irrigation Only”
- pH and isotonicity must be considered.
5. Parenteral Solution
- Injected through the skin or directly into the blood vessel, muscle, organ or tissue.
- Must conforms with strict requirements for microbiological impurity, particulate matter
and pyrogenicity.
Uses:
1. Alternative when patient is unable to take medication by mouth.
2. For drugs that are inactivated by gastric acid or first pass effect.
3. When drug action is required immediately
4. When drugs are to be delivered to an organ, lesion muscle or a nerve.
ROUTES OF PARENTERAL ADMINISTRATION
ROUTE DETAILS
Intradermal/ Intracutaneous <10 angle of injection between the epidermis and
dermis
Subcutaneous (SC or SQ) Injection between fat tissue between the dermis and the
muscles
Intramuscular Injected into muscle located in the arms/deltoid,
buttocks or legs (depot effect-slow release of
medication)
<40 angle of injection
Intravenous Injected into the veins directed to the bloodstream
Intra-arterial Injected into the arteries
Common route for chemotherapeutic drugs.
Intra-spinal Injected into the spinal cord.
- Intrathecal-- spinal canal, more specifically into
the subarachnoid space so that it reaches the
cerebrospinal fluid (CSF)
- Epidural-- injected into the epidural space of
the spinal cord. Anesthesia
EMULSION
Methods of preparation:
– Wet gum Method/ English method– (water+emulsifier) + oil (slowly) – This produces oil in
water (O/W) emulsion
– Dry Gum Method/ Continental method– (oil+emulsifier) + water (rapidly) – 4:2:1 Oil +
Water + Surfactant. This produces water in oil (W/O) emulsion.
– Bottle Method/ Forbes method – O: W: E (3:2:1) (2:1:1) – This method is used if the oil
involved is volatile oil
– Nascent Soap Method/In-situ soap method – Alkali + Fatty acid (50:30). It is the only
method that doesn’t use emulsifier in the preparation. The soap that is produced will serve
as the emulsifier.
SUSPENSIONS
– These are liquid dosage forms containing finely divided drug particles distributed somewhat
uniformly throughout a vehicle in which the drug exhibits a minimum degree of solubility.
– Reconstitution- process of adding sufficient amount of water in a dry powder (usually
antibiotic). Note that after reconstitution, the preparation will be effective and safe to use
only for 7 days if refrigerated.
– Purposes for formulating a suspension:
1. Sustaining effect
2. Stability
3. Improve the Taste
Examples:
– Gels are semisolid systems consisting of dispersions of
small or large molecules in an aqueous liquid vehicle
rendered jelly-like by the addition of a gelling-agent
– Milk is sometimes used for suspension in aqueous vehicles
intended for oral
– Magma, which is often used to describe suspensions of
inorganic acids such as clay in water.
– Lotion- are generally suspensions of solid materials in an
aqueous vehicle.
SEMI-SOLID DOSAGE FORMS
EXAMPLES
OINTMENTS – Also known as: unguents, chrisma, occulentum
– are semisolid preparations intended for external application
to the skin or mucous membranes
Uses
1. Emollients – make the skin more pliable
2. Protective barriers
3. Vehicles – in which to incorporate medication
SUPPOSITORIES
– Are solid dosage forms intended for insertion into body orifices where they melt, soften,
or dissolve and exert local or systemic effects.
– useful in infants, debilitated or comatose patients, patients who vomit, who have nausea or
gastrointestinal disturbances
– Examples:
• Rectal- Bullet or Torpedo shape
• Vaginal- also known as Pessaries. It is oviform or globular in shape
• Urethral- also known as Bougies. It is pencil-like shape.
• Otic/Ear- also known as Aurinaries
REFERENCES:
◉ Pharmacy: An introduction to the Profession, 2nd edition by Posey, L. Michael
◉ Remington : The Science & Practice of Pharmacy 21st edition by Genaro Alfonso
◉ Pharmacy by Cowen D. and Helfand W.
◉ Pharmaceutical Dosage Forms and Drug Delivery System 9th Edition Howard Ansel.
TOPIC 10:
CLASSIFICATION OF DRUGS
EXPECTED OUTCOMES:
At the end of this unit, the students are expected to:
◉ Identify the difference of prescription, OTC and dangerous drugs
◉ Determine the different examples of therapeutic classifications
◉ Discuss special information needed about different drug classifications
CHECKLIST:
◉ Read course and unit objectives
◉ Read study guide prior to class attendance
◉ Read required learning resources; refer to unit terminologies for jargons
◉ Proactively participate in discussions
◉ Participate in weekly discussion board (Canvas)
◉ Answer and submit course unit tasks
TOPIC 10: CLASSIFICATION OF DRUGS
DRUG CLASSIFICATION
NOTES:
There are different ways to classify drugs. The following are the examples:
– Based on the Branding
– Based on Prescription Used
– Based in Therapeutic Classification
2. Innovator drugs
– is the first drugs created containing its specific active ingredient to receive approval for use.
It is usually the product for which efficacy, safety and quality have been fully established.
– When a new drug is first made, drug patent usually will be acquired by the founding
company.
Patents and exclusivities are forms of protection for drug makers that may affect how and
when a generic drug is approved and can be sold. New brand-name drugs are usually
protected by patents that prohibit others from selling generic versions of the same drug.
3. Branded Generics
– A branded generic is a generic drug that has gone through the ANDA process, and is
assigned a name other than the chemical name.
– These branded generic drugs may be developed by a generic drug company, or by the
original manufacturer after patent expiration. The branded generic name is owned by the
company.
4. Dangerous Drugs
Classified by RA 9165 (Dangerous Drugs Act of 2002):
Prohibited drugs:
– These are illegal drugs that owning it without permission is punishable by the law.
– These can affect the human body or mind when it is consumed in any way
– Opium and its derivatives heroin and morphine
– Coca leaf and its derivatives cocaine; alpha and beta eucaine
– Hallucinogenic drugs mescaline, lysergic acid diethylamide
– (LSD) other substances producing similar effects Indian hemp and its derivates
Regulated drugs:
– These are drugs in which the prescribing and dispensing is controlled by an appropriate
authority (Dangerous Drug Board)
– self-inducing Sedatives secobarbital, phenobarbital, pentobarbital, barbital, amobarbital
Amphetamine benzedrine or dexedrine, or any drug which produces a physiological
action similar to amphetamine
– Hypnotic drugs methaqualone or any other compound producing similar physiological
effects
Requirements in dispensing dangerous drugs:
– Yellow prescription- 3 copies-Duplicate copies for Prescriber & Pharmacist and original
copy for the patient.
– The prescriber should special license number (S2 license)
– The drugstore outlet should have S3 license to dispense dangerous drug.
– If the customer is not the owner of the prescription, a valid ID and authorization letter should
be presented by them. The type of ID used and its number should be written at the back of
the prescription along with the full name and address of the buyer.
BASED ON
THERAPEUTIC CLASSIFICATION OF DRUGS
DRUGS AFFECTING THE CENTRAL
NERVOUS SYSTEM
ANESTHEISA
– is a drug that numbs part of your body or makes you unconscious so that you don't
experience pain during a procedure like surgery.
– Example: Local- Cocaine, Lidocaine General- Halothane, Nitrous Oxide
ANTICONVULSANT
– Also commonly known as antiepileptic drugs or as antiseizure drugs
– A diverse group of pharmaceuticals used in the treatment of epileptic seizures.
Convulsions- Excessive and abnormal electrical discharge in the brain.
– Example: Phenytoin (Dilantin), Phenobarbital
ANTI-MIGRAINE
– agents are used to treat migraine headaches.
– Migraines are different from other headaches because they occur with
symptoms such as nausea, vomiting, or sensitivity to light.
– Examples: Ergots, Sumatriptan, NSAID's.
ANTI-PARKINSONS
– An anti-parkinsons is a type of drug which is intended to treat and relieve the symptoms of
Parkinson's disease.
– The primary symptoms are muscular rigidity, slowness of movement, a resting tremor, and
postural instability
– Example: Levodopa + Carbidopa (Sinimet)
ANTIPYRETICS
– Are drugs that reduce elevated body temperature (fever) to normal levels.
– Example: Ibuprofen (Medicol, Advil), Aspirin, Paracetamol (Biogesic, Tempra)
ANXIOLYTICS
– Also known as anti-panic or antianxiety agent
– A drug used for the treatment of anxiety, and its related psychological and physical
symptoms. Anxiolytics have been shown to be useful in the treatment of anxiety disorders.
– Example: Diazepam
ANTIDEPRESSANTS
– This is a centrally acting drug that induces mood elevation, useful in treating mental
depression.
Symptoms of depression include:
– Low or irritable mood most of the time
– A loss of pleasure in usual activities
– Trouble sleeping or sleeping too much
– A big change in appetite, often with weight gain or loss
– Tiredness and lack of energy
– Feelings of worthlessness
– self-hate, and guilt
– Difficulty concentrating
– Slow or fast movements
– Lack of activity and avoiding usual activities
– Feeling hopeless or helpless
– Repeated thoughts of death or suicide
Example:
1. Fluoxetine (Prozac)
2. Imipramine (Tofranil)
ANTIPSYCHOTICS
– AKA: Major Tranquilizers
– These medications are used to treat the symptoms of mental disorders such as:
o schizophrenia
o Depression
o bipolar disorder (sometimes called manic-depressive illness)
o anxiety disorders, and
o attention deficit-hyperactivity disorder (ADHD)
– Example: Chlorpromazine, Haloperidol, Lithium Carbonate (Quilonium)
ANTI-VERTIGO
– Vertigo is a type of dizziness where there is illusion of rotatory movements.
– Antivertigo drugs are used to suppress dizziness
ANTI-MOTION SICKNESS
– A drug that suppresses motion induced nausea, vomiting, and vertigo.
– Example: Meclizine (Bonamine)
ANALGESIC
– An analgesic, or painkiller
– Any member of the group of drugs used to achieve analgesia relief
from pain.
– Example: Mild- NSAIDs, Acetaminophen Strong- Morphine,
Codeine, Fentanyl
NSAID
– Non-steroidal Anti-inflammatory Drugs
– These drugs are used to alleviate the symptoms of inflammation and to diminish its
occurrence by inhibiting the prostaglandin synthesis. (COX inhibition)
– Example: Ibuprofen (Medicol, Advil) Mefenamic Acid (Ponstan), Naproxen (Skelan, Flanax)
ANTI-RHEUMATICS
– These are anti-inflammatory drugs that are used to treat arthritis and rheumatoid disorder
chronic progressive inflammatory disorder of joints of unknown etiology.
– Inflammation leads to tissue proliferation or damage
– Examples: NSAIDs, Methotrexate
ANTI-GOUT
– A drug that reduces tissue deposits of uric acid
– Gout is a metabolic disease marked by a painful inflammation of the joints, deposits of
urates in and around the joints, and usually an excessive amount of uric acid in the blood.
– Uric acid is a waste product created during the normal breakdown of purines, naturally
occurring substances found in foods such as liver, mushrooms, anchovies, mackerel and
dried beans
– Example: Allopurinol, Cochicine, Indomethacin, Corticosteroids (prednisone).
DRUGS AFFECTING THE UTERUS
UTEROTONICS & OXYTOXICS
– Uterine stimulants
– are medications given to cause a woman's uterus to contract, or to
increase the frequency and intensity of the contractions.
– Examples: Oxytocin, Misoprostol (Cytotec)
TOCOLYTICS
– Uterine relaxants
– are drug used to suppress premature labor
– Examples: Terbutaline, Isoxuphrine (Duvadilan)
ANTACID
– A drug that neutralizes excess gastric acid. Used to treat
hyperacidity Example: Aluminum Hydroxide + Magnesium
Hydroxide + Simethicone (Kremil-S)
H-2 Blocker
– A drug that inhibits histamine-mediated gastric acid secretion used
to treat peptic ulcer and duodenal ulcers
– Example: Cimetidine
SPASMOLYTICS
– These are drugs that inhibit motility of visceral smooth muscles
– Example: Scopolamine/Hyoscine (Buscopan)
ANTIMOTILITY
– Drugs that suppresses motility or peristalsis
– It is used to relieve the symptom of diarrhea
– Example: Loperamide (Diatabs)
LAXATIVES
– Drugs that eases defecation
– Example: Pyslium fiber
ANTIEMETIC
– Drugs used to treat nausea and vomiting are called antiemetics.
– Many types of antiemetics can decrease the severity of nausea, although most require a
medical evaluation and prescription.
– Medicines available over-the-counter are mainly recommended for use in motion sickness
and for cases of mild nausea.
– Example: Meclizine (Bonamine) Metoclopramide (Plasil)
DRUGS AFFECTING THE CARDIOVASCULAR SYSTEM
Cardiovascular Diseases:
- High blood Pressure – persistent elevation of arterial blood pressure.
- Hyperlipidemia – Elevation of Cholesterol, Phospholipids and
triglycerides.
- Arrhythmia – refers to an y change from the normal sequence of electrical
impulses, causing abnormal heart rhythms
- Heart Failure – inability of the heart to pump sufficient blood to meet
body’s needs
- Ischemic Heart Disease (IHD) – Also known as CAD Lack of oxygen and
decreased or no blood flow to the heart due to coronary artery narrowing
or obstruction.
ANTI-HYPERTENSIVE
– Drugs used to lower blood pressure
– Example: Propranolol, Clonidine, Enalapril
INOTROPIC AGENTS
Also known as or inotropes, are medicines that change the force of your heart's contractions.
– Positive inotropes strengthen the heart's contractions, so it can pump more blood with fewer
heartbeats. Examples: Digoxin (Lanoxin)
– Negative inotropes weaken the heart's contractions and slow the heart rate. Examples: Beta
blockers
ANTI-ANGINAL DRUGS
– are medicines that relieve the symptoms of angina pectoris (severe chest pain).
– Example: Nitroglycerin
ANTIARRHYTHMIC
– A cardiac depressant useful in suppressing rhythm irregularities of the heart.
– Example: Lidocaine, Quinidine
ANTI-LIPIDEMIC
– or antihyperlipidemic agents, are a diverse group of pharmaceuticals that are used in the
treatment of hyperlipidemias. They are called lipid-lowering drugs.
– Examples: Statins (Simvastatin)
NASAL DECONGESTANT
– a type of pharmaceutical drug that is used to relieve nasal congestion in
the upper respiratory tract
– Example: Phenylephrine
RESPIRATORY STIMULANT
– is primarily used in addition to noninvasive ventilation as a means to help increase the urge
to breathe.
– Example: Caffeine
FIBRINOLYTIC
– A drug that promotes removal of small fibrin clots
– It is useful in removing blood clots that are already formed.
– Examples: Streptokinase
ANTI-FIBRINOLYTIC
– Also known as Hemostatics
– A drug that promotes homeostasis by inhibiting clot dissolution
– Useful in the management of severe bleeding.
– Example: Tranexamic Acid
REFERENCES:
◉ Pharmacy: An introduction to the Profession, 2nd edition by Posey, L. Michael
◉ Remington : The Science & Practice of Pharmacy 21st edition by Genaro Alfonso
◉ Pharmacy by Cowen D. and Helfand W.
END OF MODULE