PENGARUH PENAMBAHAN NATRIUM BENZOAT SEBAGAI AGEN HIDROTROPIK TERHADAP

KELARUTAN PENTAGAMAVUNON-0
NURUL PANGESTUTI, Prof. Dr. Suwaldi M, M.Sc., Apt
Universitas Gadjah Mada, 2017 | Diunduh dari http://etd.repository.ugm.ac.id/

DAFTAR PUSTAKA

Anonim, 2008, British Pharmacopoeia Volume 1 & II,

http://www.uspbpep.com/bp2008/data/7646.asp, diakses pada 1
Desember 2016.
Anonim, 2015, Search for Chemicals. Sodium Benzoate (CAS 532-32-1)
Registered Substances Dossier. European Chemical Agency,
https://pubchem.ncbi.nlm.nih.gov/compound/sodium_benzoate#section=
Flash-Point , 26 November 2016.
Anonim, 2011, The United States Pharmacopeia 34 and The National Formulary
29, United States Pharmacopeial Converntion, USA
Anonim, 2001, Uji Anti Inflamasi Senyawa PGV-0, PGV-1, dan HGV-1, pada
Tikus Jantan dan Betina, dan Elusidasi Mekanisme Anti Inflamasi,
Laporan Penelitian TIM Molnas, Fakultas Farmasi Universitas Gadjah
Mada, Yogyakarta.
Anonim, 1997, Compendium of Chemical Terminologi, 2nd Edition ( The “Gold
Book”), Blackwell Scientific Publications, Oxford.
Aulton M, 2002, Dissolution and Solubility, Pharmaceutics: The Science of
Dosage Form Design, 2nd Edition, Churchill Livingstone, London.
Bahremand, N. dan Eskandari, S., 2013, Determination of Potassium Sorbate and
Sodium Benzoate in “Doogh” by HPLC and Comparison with
Spectrophotometry, International Journal of Bio-Inorganic Hybrid
Nanomaterials Vol. 2 No. 3, 429-435.
Bauduin, P., Renoncourt, A., Kopf, A., Touraud, d., Kunz, w., 2005, Unified
Concept of Solubilization in Water by Hydrotropes and Cosolvent,
Langmuir, 21, 6769-6775.
Basir, D.N., 2015, Spektrofotometer UV-Vis, Laporan Penelitian, Universitas
Hasanudin Makassar.
Behera, A.L., Sahoo S.K., S.V., 2010, Enhancement Solubility : A Pharmaceutical
Overview, Der Pharmacia Lettre, 2(2) : 310-318
Beiq, A., Lindley, D., Miller, J.M., Aqbaria, R., Dahlan, A., 2016, Hydrotropic
Solubilization in Lipophilic Drugs for Oral Delivery : The Effects of
Urea and Nicotinamide on Carbamazepine- Solubility and Permeability
Interplay, Frontiers in Pharmacology, 7:379.
Bustamante, C. dan Bustamante, P., 1996, Non Linear Enthalpy Entrophy
Compensation for Solubility of Phenacetine in Dioxine-Water Solvent
Mixture, Journal Pharmaceutical Sciences : 1109-1110.
Chaurasia, G., 2016, A Review on Pharmaceutical Preformulation Studies in
Formulation and Development of new Drug Molecules, International
Journal of Pharmaceutical Sciences and Research, 7(6): 2313-20.
Connor dkk, 1986, Chemical Stability of Pharmaceuticals : A Handbook for
Pharmacist Second Edition, John Wiley & Son, New York.

70
70
 PENGARUH PENAMBAHAN NATRIUM BENZOAT SEBAGAI AGEN HIDROTROPIK TERHADAP
KELARUTAN PENTAGAMAVUNON-0 71
NURUL PANGESTUTI, Prof. Dr. Suwaldi M, M.Sc., Apt
Universitas Gadjah Mada, 2017 | Diunduh dari http://etd.repository.ugm.ac.id/

Dahlan, A., Miller J.M., Amidon, G.L. 2009, Prediction of Solubility and
Permeability Class Membership : Provisional BCS Classification of The
World’s Top Oral Drug, The American Association of Phramaceutical
Scientist Journal Vol 11.
Deepshikha, S.,Vaibhav, S., Kharia, A.A., dan Chatterjee, D.P., 2012, Techniques
for Solubility Enhancement for Poorly Soluble Drugs : An Overview,
Journal of Medical Pharmaceutical and Allied Sciences 01 : 18 -38,
Oriental College of Pharmacy, Bhopal.
Dhapte dan Mehta, 2015, Advances in Hyrotropic Solution : An Updated
Review. St. Petersburg Polytechnical University Journal : Physics and
Mathematics, Volume 1, Issue 4, 424-435.
Diana, M., 2004, Pengaruh pH terhadap Kelarutan Pentagamavunon-0 (PGV-0),
Skripsi, Fakultas Farmasi Universitas Gadjah Mada, Yogyakarta.
Florence, A.T. and Attwood, D., 2002, Physicochemical Principles of Pharmacy
4th Edition, Mc Millan, Hongkong.
Gandjar, I.G. & Rohman, A., 2012, Kimia Farmasi Analisis, Pustaka Pelajar,
Yogyakarta.
Istyastono, E.P., Siwi, R.S.U., Utama, A.A., dan Suparjan, A.M., 2002, Sintesis
Uji Daya Anti-Inflamasi Natrium Pentagamavunonat-0, Laporan
Penelitian, Fakultas Farmasi Universitas Gadjah Mada, Yogyakarta.

Jhariya, A.N., Joshi, A., Parashar, A.K., Nema, R.K., Application of Sodium
Citrate As Hydrotropic Agent in Spectrophotometric Analysis of
Salicylic Acid, International Journal of Pharmaceutical Sciences and
Research, India.
Jain, A., 2008, Solubilization of Indometachin Using Hydrotropes for Aqueous
Injection, European Journal od Pharmacy. Biopharm 68 701-714.
Kumar, V.S., Raja, C., Jayakumar, C, 2014, A Review on Solubility
Enhancement Using Hydrotropic Phenomena, International Journal od
Pharmaceutical Science, 6,1-7
Kurniawati, I., 1999, Metode Analisis Kuantitatif Pentagamavunon-0 pada Tikus
Putih, Skripsi, Fakultas Farmasi, Universitas Gadjah Mada, Yogyakarta.
Lachman, L., Liebermen H.A., dan Kanig J.L., 1986, The Theory and Practise of
Industrial Pharmacy 3rd Edition, Lea & Febiger, Philadelphia.
Maheshwari, R K., Chaturvedi, S.C., Jain, N.K., 2007, Novel Application of
Hydrotropic Solubilization in The Quantitative Analysis of Some
NSAIDs and Their Solid Dosage Forms, Indian Journal of
Pharmaceutical Science, http://www.ijpsonline.com/articles/novel-
application-of-hydrotropic-solubilization-in-the-analysis-of-some-nsaids-
and-their-solid-dosage-forms.html, 5 Juni 2017.
Maheshwari, R.K., Chavada, V., Varghese, S., Shahoo, 2008, Analysis of Bulk
Sample of Salicylic Acid by Application of Hydrotropic Solubilization
 PENGARUH PENAMBAHAN NATRIUM BENZOAT SEBAGAI AGEN HIDROTROPIK TERHADAP
KELARUTAN PENTAGAMAVUNON-0 72
NURUL PANGESTUTI, Prof. Dr. Suwaldi M, M.Sc., Apt
Universitas Gadjah Mada, 2017 | Diunduh dari http://etd.repository.ugm.ac.id/

Method, Indian Journal Pharmaceutical Science, 70(6): 823-825,

http://www.ijpsonline.com/articles/analysis-of-bulk-sample-of-salicylic-
acid-by-application-of-hydrotropic-solubilization-method.html, 5 Juni
2017.
Maheshwari, R.K., Moond, S., More, M.M., Prajapati, S.P., Verma, S., 2010,
Quantitative Spectrophotometric Determination of Cefixime Tablet
Formulation Using Sodium Tartrate as Hydrotropic Solubilizing Agent,
Departement of Pharmacy, Indore, India.
Martin, A., Bustamante, P., dan Chun, A.H.C., 1993, Physical pharmacy :
Physical Chemical Principles in The Pharmaceutial Sciences, 4th
Edition, Lea & Febiger, Philadelphia.
Nidhi, K., Indrajeet, Singhvi., Khushboo M.H., Gauri K., Sen D.J., 2011,
Hydrothropy : A Promising Tool For Solubility Enhancement : A
Review, International Journal of Drug Development and Research, 3(2)
: 26-33, http://www.ijddr.in/drug-development/hydrotropy-a-promising-
tool-for-solubility-enhancementa-review.pdf, 20 Juli 2017.
Neumann, M.G., Schmitt, C.C., Prieto, K.R., Goi, B.E., 2007, The Photo Physical
Determination of The Minimum Hydrotrope Concetration of Aromatic
Hydrotropes, Journal of Colloid Interface Science, 315;810-813
http://www.sciencedirect.com/science/article/pii/S0021979707009733,
21 Juli 2017.
Nurrochmad, A., 1997, Penghambatan Biosintesis Prostaglandin Melalui Jalur
Siklooksigenase oleh Siklovan dan Tiga Senyawa Analognya, Fakultas
Farmasi, Universitas Gadjah Mada, Yogyakarta.
Paladiya, S., Chauchan, C.C., Jotania, R.B. 2010, Physical Property of
Magnesium Doped Barium Hexaferrite by Citrate Precursor Route in
Presecnce of Surfactants, AIP Conference Proceedings, Thapal
University Patiala.
Pridianingsih, R.A., 2017, Pengaruh Penambahan Kafein sebagai Agen Hidrotrop
terhadap Kelarutan Pentagamavunon-0, Skripsi, Fakultas Farmasi,
Universitas Gadjah Mada, Yogyakarta.
Patel, S.K., Kumar D., Waghmode A.p., Dhabale A.S., 2011, Solubility
Enhancement of Ibuprofen Using Hydrotropic Agents, International
Journal of Pharmacy and Life Sciences,
http://www.ijplsjournal.com/issues%20PDF%20files/feb%202011/1.pdf,
5 Juni 2017.
Rasool, A.A., Hussain, A.A., Dittert, L.W., 1991, Solubility Enhancement of
Some Water Insoluble Drugs in The Presence of Nicotinamide and
Related Compounds, Journal of Pharmaceutical Sciences, 4, 387-393.
 PENGARUH PENAMBAHAN NATRIUM BENZOAT SEBAGAI AGEN HIDROTROPIK TERHADAP
KELARUTAN PENTAGAMAVUNON-0 73
NURUL PANGESTUTI, Prof. Dr. Suwaldi M, M.Sc., Apt
Universitas Gadjah Mada, 2017 | Diunduh dari http://etd.repository.ugm.ac.id/

Roy dan Moulik, 2002, Functions of Hydrotropes (Sodium Salicylate, Proline,

Pyrogallol, Resorcinol, and Urea) in Solution with Special Reference to
Amphiphile Behaviors, Colloids and Surfaces A Physicochemical and
Engineering Aspects, Vol.203,no 1-3, 155-166.
Sajid, M.A. dan Choudhary V, 2012, Solubility Enhancement Methods With
Importance od Hydrotropy, Journal of Drug Delivery and Therapeutics
2(6) 96-101
Sardjiman, 1993, Synthesis 2,6-Bis-(3’,5’-dimetil 4’ hidroksibenzilidin)
sikloheksanon; 2,5 -Bis-(4’ –hidroksi- 3’ –metoksibenzilidin
siklopentanon dan Pentadien -3-on dan Daya Antioksidannya, Laporan
Penelitian, Fakultas Farmasi Universitas Gadjah Mada, Yogyakarta.
Sardjiman, 2000, Synthesis of Some New Series of Curcumin Analouges,
Antioxidative, Anti Inflammatory, Anti Bacterial Activities, dan Qualit
tive Structure-Activity Relationships, Disertasi, Fakultas Farmasi
Universitas Gadjah Mada, Yogyakarta.
Savjani, K.T., Gajjar A.K., dan Savjani J.K., 2012, Drug Solubility : Importance
and Enhancement Techniques, International Scholary Research Network,
Institute of Pharmacy, Nirma University, India.
Sharma, R.A., Gescher, A.J., Steward, W.P., 2005, Curcumin : The Story So Far,
European Journal of Cancer, www.ejconline.com, 2 Desesmber 2016
Sharma, B.K., 2007, Spectroscopy Ed 20, GOEL Publishing House, Delhi
Shete, A.S., Yadav, A.V., Dable, A.P., Sakhare, S.S., dkk, 2010, Formulation and
Evaluation od Hydrotropic Solubilization Based Suspensions of
Griseofulvin, International Journal of Pharma Sciences and Research,
India.
Stegemann, S., Leveiiller F, Franchi D., Jong D.H., Linden, H., 2007, When Poor
Solubility Becomes An Issue : From Early Stage to Proof of Concept,
European Journal of Pharmaceutical Sciences, European Federation of
Pharmaceutical Sciences Elsevier, (5):249-61.
Thakkar, A.L. dan Tensmeyer, L.G., 1974, Complexation of Theophylline with
Natrium Benzoate : An NMR Study, Journal of Pharmaceutical Sciences,
http://jpharmsci.org/article/S0022-3549(15)41765-4/pdf, 18 Juli 2017
Vadlamudi, K.M., Dhanaraj, S., 2016, Disparate Practical Way of Doing
Solubility Enhancement Study to Improve The Bioavailibility of Poorly
Soluble Drugs, Journal of Chemical and Pharmaceutical Research,
www.jocpr.com, diakses pada 10 Juli 2017
Voight, R, 1994, Buku Pelajaran Teknologi Farmasi Edisi 5, Gadjah Mada
University Press, Yogyakarta.
 PENGARUH PENAMBAHAN NATRIUM BENZOAT SEBAGAI AGEN HIDROTROPIK TERHADAP
KELARUTAN PENTAGAMAVUNON-0 74
NURUL PANGESTUTI, Prof. Dr. Suwaldi M, M.Sc., Apt
Universitas Gadjah Mada, 2017 | Diunduh dari http://etd.repository.ugm.ac.id/

Wahyuni, A.S., 1999, Perbandingan Daya ulserogenik antara Senyawa

Pentagamavunon-0 dan Asetosal pada Lambung Tikus Putih, Skripsi,
Fakultas Farmasi Universitas Gadjah Mada, Yogyakarta.
Wahyuni, A.S., 1998, Pengaruh Daya Ulserogenik PGV-0 pada Lambung Kelinci
dengan Berbagai Kadar, Skripsi, Fakultas Farmasi Universeitas Gadjah
Mada, Yogyakarta.
Wu, C.Y. dan Benet L.S., 2005, Predicting Drug Disposition Via Application of
BCS: Transport / Abrosption Elimination Interplay & Development of a
Biopharmaceutical Drug Disposition Classification System,
Pharmaceutical Research 22 (1), 23-27