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    Cymbalta

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    This document provides information about the medication Duloxetine (Cymbalta) including its classification, dose, route, time/frequency of administration, pharmacokinetics, mechanism of action and indications, nursing implications, interactions, lab alterations, patient education points, and the nursing process for assessment and administration. Duloxetine is an antidepressant and pain inhibitor that works by inhibiting serotonin and norepinephrine reuptake. It is given orally once daily to treat depression and pain. Nurses should monitor for side effects, contraindications, and interactions and educate patients about proper administration and monitoring for worsening symptoms.

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    Cymbalta

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    E
    887 views2 pages
    This document provides information about the medication Duloxetine (Cymbalta) including its classification, dose, route, time/frequency of administration, pharmacokinetics, mechanism of action and indications, nursing implications, interactions, lab alterations, patient education points, and the nursing process for assessment and administration. Duloxetine is an antidepressant and pain inhibitor that works by inhibiting serotonin and norepinephrine reuptake. It is given orally once daily to treat depression and pain. Nurses should monitor for side effects, contraindications, and interactions and educate patients about proper administration and monitoring for worsening symptoms.

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    This document provides information about the medication Duloxetine (Cymbalta) including its classification, dose, route, time/frequency of administration, pharmacokinetics, mechanism of action and indications, nursing implications, interactions, lab alterations, patient education points, and the nursing process for assessment and administration. Duloxetine is an antidepressant and pain inhibitor that works by inhibiting serotonin and norepinephrine reuptake. It is given orally once daily to treat depression and pain. Nurses should monitor for side effects, contraindications, and interactions and educate patients about proper administration and monitoring for worsening symptoms.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    887 views2 pages

    Cymbalta

    Uploaded by

    E
    This document provides information about the medication Duloxetine (Cymbalta) including its classification, dose, route, time/frequency of administration, pharmacokinetics, mechanism of action and indications, nursing implications, interactions, lab alterations, patient education points, and the nursing process for assessment and administration. Duloxetine is an antidepressant and pain inhibitor that works by inhibiting serotonin and norepinephrine reuptake. It is given orally once daily to treat depression and pain. Nurses should monitor for side effects, contraindications, and interactions and educate patients about proper administration and monitoring for worsening symptoms.

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    of 2

    NURS 2516 Clinical Medications Worksheets

    (You will need to make additional copies of these forms)

    Generic Name Trade Name Classification Dose Route Time/frequency


    Duloxetine Cymbalta Antidepressants 20mg PO 0900 daily
    (SSNRIs)
    Peak Onset Duration For IV meds, compatibility with IV drips and /or solutions
    6 hr unknown 12 hr N/A

    Mechanism of action and indications Nursing Implications (what to focus on)


    (Why med ordered) Contraindications/warnings/interactions
    Inhibits serotonin and norepinephrine reuptake in the Hypersensitivity. Use cautiously in: History of suicide
    CNS. Both antidepressant and pain inhibition are attempt or ideation; History of mania (may activate
    centrally mediated. mania/hypermania); Concurrent use of other centrally-acting
    Depression, pain. drugs (increased risk of adverse reactions); History of seizure
    disorder. Pedi: May increase risk of suicide attempt/ideation
    especially during dose early treatment or dose adjustment;
    risk may be greater in children and adolescents (safe use in
    children and adolescents not established). Increased risk of
    hepatotoxicity with alcohol use.
    Common side effects
    SEIZURES, fatigue, drowsiness, insomnia, decreased
    appetite, constipation, dry mouth, nausea, dysuria,
    increased sweating
    Interactions with other patient drugs, OTC or herbal Lab value alterations caused by medicine
    medicines (ask patient specifically) May increase ALT, AST, bilirubin, CPK, and alkaline
    none phosphatase.
    Be sure to teach the patient the following about this
    medication
    Instruct pt. to take as directed at the same time each day.
    Take missed doses as soon as possible unless time for next
    dose. Do not stop abruptly; must be decreased gradually.
    Encourage pt. and family to be alert for emergence of
    anxiety, agitation, panic attacks, insomnia, irritability,
    hostility, impulsivity, akathisia, hypomania, mania,
    worsening of depression and suicidal idealation, especially
    during early antidepressant therapy. If these symptoms,
    notify health care professional. May cause drowsiness.
    Caution pt. to avoid driving or other activities requiring
    alertness until response to medication is known. Advise pt to
    consult health care professional prior to taking any Rx, OTC,
    or herbal products. Instruct p. to notify healthcare
    professional if signs of liver damage (pruritus, dark uring,
    jaundice, right upper quadrant tenderness, unexplained “flu-
    like symptoms) occur. Advise pt. to avoid taking alcohol
    during duloxetine therapy. Instruct pt. to notify health care
    professional if pregnancy is suspected.

    Nursing Process- Assessment Assessment Evaluation


    (Pre-administration assessment) Why would you hold or not give this Check after giving
    Monitor blood pressure before and med? Increased sense of well-being,
    periodically during therapy. Monitor appetite Sustained hypertention, occurrence of renewed interest in
    and nutritional intake. Assess mental status severe side effects. surroundings. Need for
    and mood. Assess suicidal tendencies. therapy should be periodically
    Assesspain intensity, quality, and location. reassessed. Pts. May notice
    improvement within -4 wks,
    but should be advised to
    continue therapy as directed.
    Therapy is usually continued
    for several months.

    Dose Range: no pediatric range available because safe use in children/adolescents is not
    established. Adult dose range for antidepressant use is 20-30 mg twice daily and for
    neuropathic pain is 60 mg once daily.

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