Goldfarb 2008
Goldfarb 2008
Goldfarb 2008
Purpose To assess the long-term subjective and objective outcome of cleft reconstruction in
patients with central ray deficiency.
Methods Twelve patients with 16 central ray deficiency hands were included. Each hand had
been treated with cleft reconstruction using soft tissue and/or bony procedures. A surgeon
and parent assessed the subjective outcome using a visual analog scale to compare preop-
erative and postoperative appearance. Objective outcome was assessed with a clinical
examination for digital range of motion and with a radiographic examination for preoperative
and postoperative divergence angles of the index finger and ring finger metacarpals and
phalanges.
Results The surgeon’s visual analog scale score significantly increased from 4 to 7. Nine
parents were very satisfied, 4 were satisfied, and 3 were somewhat satisfied with hand
appearance. A ring finger proximal interphalangeal joint flexion contracture averaging 31°
was the most notable clinical finding. The metacarpal divergence angle significantly im-
proved from 33° to 12°, and the phalangeal divergence angle significantly improved from 38°
to 12°.
Conclusions Cleft reconstruction improves hand appearance in patients with central deficiency. A
new technique of quantifying the radiographic divergence of the border rays of the cleft
demonstrates improved alignment at long-term follow-up. (J Hand Surg 2008;33A:1579–1588.
Copyright © 2008 by the American Society for Surgery of the Hand. All rights reserved.)
Type of study/level of evidence Therapeutic IV.
Key words Appearance, central deficiency, cleft hand, reconstruction, transposition.
LEFT HAND, OR CENTRALlongitudinal deficiency, web space.4 Central longitudinal deficiency should be
1 R No No I II
2 L No No I II
R III II
3 R Yes Right foot deficiency and IIA II
syndactyly, EEC
4 R Yes No IIA II
L IIA II
5 R No No I II
6 R Yes Left foot syndactyly, IIB II
duplicated great toe
7 R Yes No III II
8 R No No IIA II
9 R No No IIA II
10 R Yes Left index finger I II
clinodactyly
L I II
11 L No No III II
12 L Yes Right foot syndactyly IIA II
R IIA II
*The Manske classification3 is based on the quality of the first web space. The Ogino classification10 is based on the bony central deficiency.
EEC, ectrodactyly ectodermal dysplasia and cleft lip/palate syndrome.
treated with a rotational flap from the cleft. Finally, imbrication of the extensor mechanism, and 1 had an
the 3 patients with type III hands were treated with extensor indicis proprius transfer.
rotational flaps and full-thickness skin grafts. Three
patients required a secondary procedure on the first Assessments
web space (2 had revision procedures to deepen the Subjective data:
first web space at an average of 18 months after the
● One of the authors (C.A.G.) not involved in the
initial surgery, and 1 type IIA patient who did not
have the first web addressed at the initial procedure initial surgical procedures evaluated clinical pho-
had a thumb–index finger z-plasty). tographs before and after surgical intervention (at
last follow-up) for all 16 hands (Figs. 1, 2). Using
Ring finger–small finger syndactyly: Seven hands had ring a visual analog scale (VAS), he rated the hand
finger–small finger syndactyly. Three of these 7 hands appearance with particular attention paid to the
were reconstructed at the time of the initial cleft recon- cleft. A score of 1 corresponded with a severely
struction, and 2 were treated as secondary procedures. abnormal hand, and a score of 10 corresponded
In 2 patients, the syndactyly was not reconstructed per with a normal hand. Scores were averaged and
the desires of the family. rounded to the closest whole number for reporting
Additional procedures: Additional bony procedures were and comparison.
performed for 6 hands at an operative session separate ● The primary caregiver, most commonly the pa-
from that of the cleft reconstruction. Three hands (5 tient’s mother, was queried by a research assistant
digits) required a rotational osteotomy of the index- not involved in the care of the patient as to the
finger or ring-finger metacarpal or phalanges. Three caregiver’s satisfaction with the surgical interven-
hands were treated for an extensor lag at the proximal tion including appearance, function, and pain.
interphalangeal (PIP) joint of the ring finger; 2 had an Choices included very satisfied, satisfied, some-
1 R 12 Y-shaped Yes No No
2 L 14 Y-shaped No (bifid portion No No
excised)
2 R 21 Present Yes Yes No
3 R 13 Present Yes No No
4 R 19 Present Yes No Yes
4 L 21 Present Yes Yes Yes
5 R 19 Present Yes No Yes
6 R 12 Y-shaped No (bifid portion No Yes
excised)
7 R 13 Present Yes No Yes
8 R 38 Present Yes Yes No
9 R 39 Absent NA Yes, oblique osteotomy No
of second metacarpal
10 R 12 Present Yes Yes Yes
10 L 20 Absent NA No Yes
11 L 20 Present Yes Yes No
12 L 19 Absent NA No Yes
12 R 20 Absent NA Yes, oblique osteotomy No
of second metacarpal
FIGURE 1: Clinical appearance of a typical cleft in a central deficiency hand prior to reconstruction: A dorsal view and B volar view.
FIGURE 2: Clinical appearance of a typical cleft in a central deficiency hand after reconstruction: A dorsal view and B volar view.
FIGURE 3: Radiograph before reconstruction with depiction of measurement technique for both A metacarpal and B phalangeal
divergence angles. The metacarpal divergence angle was 40°, and the phalangeal divergence angle was 60°.
what satisfied, and not satisfied. Older patients was paid to the presence of a flexion deformity at
provided input on these questions. the PIP joint and to finger alignment abnormalities.
Objective data: Radiographic data:
● Postoperative range of motion of the index, ring, ● Preoperative, immediate postoperative, and final
and small fingers was assessed. Particular attention postoperative radiographs were reviewed to assess
for alignment of the digits bordering the cleft. We suring the angle formed by lines drawn through the
determined the angle of divergence between the center of their longitudinal axis on a standard
index-finger and ring-finger metacarpals by mea- posteroanterior x-ray. Similarly, we measured the
angle of divergence between the index-finger and
ring-finger proximal phalanges—the phalangeal
divergence angle (Figs. 3 and 4).
Statistical analysis
A statistical analysis was performed to assess the data.
Paired t-tests were used to assess change in VAS scores
and the change in the divergence angle. Significance
was set at .05.
RESULTS
Subjective data
The surgeon’s VAS score improved from 4 (range,
2–7) preoperatively to 7 (range, 5–9) postoperatively, a
significant improvement (p ⫽ .02). When subdivided
by severity (Manske3 type), the 5 type I hands had an
average VAS score of 5 preoperatively and 8 postop-
eratively (significant improvement, p ⫽ .007). The 8
FIGURE 4: Radiograph after reconstruction in the patient of
type II hands (including type IIA and IIB) had an
Figure 3. The metacarpal divergence angle and the phalangeal average VAS score of 4 preoperatively and 7 postop-
divergence angle were both 20°, one of the largest eratively (significant improvement, p ⬍ .002). Finally,
postoperative deformities in this series. the 3 type III patients had an average VAS score of 3
MCP, metacarpophalangeal; PIP, proximal interphalangeal; DIP, distal interphalangeal; NA, not applicable.
(Continued)
preoperatively and 6 postoperatively (significant im- data in each patient as documented in the medical
provement, p ⫽ .02). record. Three hands had a residual rotational abnormal-
Subjectively, 9 parents were very satisfied about the ity of the ring finger at the time of final follow-up;
hand appearance, 4 were satisfied, and 3 were only function was not affected in these patients.
somewhat satisfied. All believed the hand appearance
was improved, and none were dissatisfied with the final Radiographic data
hand appearance. Four patients with bilateral involve- The divergence angles are noted in Table 5.
ment were included in this investigation; 2 of the care- The metacarpal divergence angle between the index-
givers were satisfied with both hands, and 2 were very finger and ring-finger metacarpals averaged 33° (range,
satisfied with 1 hand and only somewhat satisfied with 10° to 60°) preoperatively, 15° (range, 5° to 40°) im-
the other. Four patients had rare pain and the other 8 mediately after surgery, and 12° (range, 0 to 40°) at
denied pain. Subjective functional improvements were final follow-up. The improvement from before surgery
most commonly attributed to restoration of the first web to final follow-up was significant (p ⫽ .0005) as was
space. All patients were able to perform normal daily the improvement from before surgery to immediately
activities with the affected hand(s). after surgery (p ⫽ .002). There was no significant
difference in the metacarpal divergence angle immedi-
Objective data ately after surgery compared with that at final follow-up
Postoperative range of motion was considered normal (p ⫽ .16).
for all 3 fingers in 7 hands (5 patients); the other 9 hands The phalangeal divergence angle between the index-
had some loss of motion involving at least 1 joint (Table finger and ring-finger proximal phalanges averaged 38°
4). The most notable abnormality was the limited active (range, 25° to 80°) before surgery, 15° (range, 0 to 45°)
and passive extension of the ring-finger PIP joint. Only immediately after surgery, and 12° (range, 10° conver-
9 hands had full PIP joint extension of the ring finger, gent to 50°) at final follow-up. The improvement from
and the other 7 hands had an average 31° loss of before surgery to final follow-up was significant (p ⬍
extension (range, 20° to 55°). These postoperative .003) as was the improvement from before surgery to
range of motion data were similar to the preoperative immediate after surgery (p ⬍ .007). There was no
10 59 43 56 NA 22 10 60 15 85 NA NA
1 R 30 5 0 25 0 5
2 R 60 40 45 45 45 50
2 L 60 10 10 50 5 5
3 R 40 0 20 65 15 20
4 R 25 15 15 55 15 5
4 L 45 35 25 30 10 10
5 R 7 0 0 82 5 25
6 R 45 25 25 60 30 10
7 R 25 15 0 40 5 0
8 R 25 20 0 30 20 25
9 R 60 20 20 40 20 0
10 R 25 0 0 15 10 10
10 L 15 15 15 0 15 15
11 L 15 10 10 30 15 15
12 R 30 15 0 25 20 0
12 L 15 20 0 10 10 0
Average 33 15 12 38 15 12
t-test: Metacarpal immediately postoperative:Metacarpal final, p ⫽ .164; Metacarpal preoperative:Metacarpal immediately postoperative, p ⬍ .023;
Metacarpal preoperative:Metacarpal final, p ⬍ .005.
Phalangeal immediately postoperative:Phalangeal final, p ⫽ .321; Phalangeal preoperative:Phalangeal immediately postoperative, p ⬍ .007;
Phalangeal preoperative:Phalangeal final, p ⬍ .003.
significant difference in the phalangeal divergence an- this difference was not significant (p ⫽ .35), suggesting
gle immediately after surgery compared with that at that a larger preoperative divergence angle did not pre-
final follow-up (p ⫽ .32). dispose to a larger, final divergence angle (Table 5). We
There was no significant difference between the evaluated 3 variables that we believed may have con-
metacarpal and phalangeal divergence angles at any tributed to the failure to maintain a straighter alignment:
measurement point (p ⬎ .83). the presence/absence of a third metacarpal, the perfor-
The metacarpal divergence angles improved at the mance of a second to third metacarpal transposition, (ie,
immediate and final postoperative evaluation in 14 of Snow-Littler procedure), and the performance of a
the 16 hands; 1 hand had an increased angle at the transverse metacarpal ligament reconstruction. We
immediate postoperative evaluation but improved at the were unable to demonstrate that any of these 3 surgical
final evaluation, and 1 was unchanged. Similarly, 14 of factors decreased the risk of a persistent divergence
the 16 preoperative phalangeal divergence angles im- angle of more than 15°.
proved at the immediate and final postoperative evalu-
ations; 1 was unchanged at the immediate postoperative DISCUSSION
visit but improved at the final evaluation, and 1 had The subjective results of this investigation were very
increased proximal phalangeal divergence angle at both good in that families were satisfied with the surgical
postoperative evaluations. intervention and found the appearance of the hand to be
Seven of the 16 hands (including the 2 hands with improved; this is similar to less vigorous outcome eval-
increased divergence) had a final metacarpal or phalan- uations of previous reports.5,6,10,11 The VAS scores,
geal divergence angle of more than 15°. The preoper- range of motion measurements, and the metacarpal and
ative metacarpal divergence angle averaged 34° in phalangeal divergence angle measurements provide an
those patients compared with 31° in the other patients; objective confirmation of the improved appearance.
There are few objective outcome data in the previous have not used the flexor digitorum superficialis trans-
studies of central deficiency reconstruction to allow fer10 to address this deficiency. The flexed posture of
comparison. the ring-finger PIP joint did not cause marked func-
The radiographic outcome of central deficiency re- tional difficulties but was primarily an appearance
construction has not been previously reported. Use of issue.
an index-finger and ring-finger metacarpal divergence One technical component of the reconstruction of
angle and/or proximal phalanx divergence angle allows central ray deficiency that has received extra attention is
an objective assessment of cleft reconstruction to pro- the reconstruction of the transverse metacarpal ligament
vide an improved understanding of alignment. The between the index-finger and ring-finger metacarpals.
metacarpal divergence angle measures the true “cleft” Tada10 primarily used an autogenous tendon graft in a
angle and allows an accurate assessment of any recon- circular fashion through both metacarpals and called it
struction. The phalangeal divergence angle is also help- “an essential part of closure of the cleft.” Ogino11
ful as it measures the clinical alignment of the digits cautioned overtightening such tendon grafts and instead
that, by definition, includes any compensatory angula- used flaps from the adjacent flexor sheaths. This recon-
tion (or convergence) of the metacarpophalangeal or struction was in an anatomic position and was not
PIP joints. In this series, surgery provided a significant susceptible to overtightening. A simple, alternative
improvement in both angles that was maintained at final method is to cut the adjacent A1 pulleys and suture
follow-up. Rider et al.5 measured divergence as the them together.1 Rider et al.5 reported on the Snow-
distance in millimeters between the index-finger and Littler procedure in 13 hands with central deficiency.
ring-finger metacarpal heads. Although this measure- They reconstructed the transverse metacarpal ligament
ment technique provides objective data, we believe use in 8 of the 13 hands. Notably, the 5 hands without
of divergence angles is less dependent on patient size reconstruction had no evidence of instability or radio-
and radiographic magnification and is, therefore, a more graphic divergence.
useful measurement. Our investigation did not find a difference in final
Seven of the 16 hands had a final metacarpal diver- divergence angle in patients with or without reconstruc-
gence angle or phalangeal divergence angle greater than tion of the transverse metacarpal ligament. If good
15°. We evaluated 3 variables that we believed may balance and alignment are achieved at surgery by bony
have contributed to the failure to maintain a straighter transposition, a reconstruction of the transverse meta-
alignment: the presence/absence of a third metacarpal, carpal ligament may not be necessary. In contrast, if
the performance of a second to third metacarpal trans- good balance and alignment are not achieved at the time
position (i.e., Snow-Littler procedure), and the perfor- of surgery, it is unlikely the ligament reconstruction can
mance of a transverse metacarpal ligament reconstruc- balance the hand to a satisfactory degree.
tion. We were unable to demonstrate that any of these One weakness of this study is the small number of
3 features affected the final angle of divergence. patients included; however, this limitation is frequently
Seven of the 16 hands in this investigation had a seen in patients with uncommon congenital abnormal-
notable flexion contracture of the ring-finger PIP ities. We believe the size of our patient group is accept-
joint. Ogino11 previously noted that the ring-finger able considering the narrow inclusion criteria and the
flexion deformity was likely related to “dysfunction” relatively structured approach to the cleft reconstruction
of the intrinsic muscles. He recommended flexor for these patients. Additionally, this study evaluated the
digitorum superficialis transfer to the base of the subjective and objective outcome of the cleft deformity
proximal phalanx of the ring finger or a split transfer, specifically. Although our objective measures could
in the case of index finger–ring finger divergence, to accomplish this goal, the subjective outcome (both for
the radial base of the ring finger and ulnar base of the the surgeon and for the parent) is less easily isolated to
index finger. Tada10 also noted that there was re- the cleft. The surgeon and the parents were instructed to
duced active extension of the PIP joint of the ring focus their assessment to the cleft (ideally avoiding
finger due to hypoplasia of the third lumbrical. We consideration of the first web space and the ring and
agree with these hypotheses, as the radial-sided in- small fingers); in practicality, this may have been dif-
trinsic structures to the ring finger are likely to be ficult to accomplish.
affected by the central ray deficiency. The presence
or absence of the third metacarpal did not contribute REFERENCES
to the flexed position, as the third metacarpal was 1. Kantarincic J. Cleft hand. J Am Soc Surg Hand 2003;3:108 –116.
present in 5 hands and absent in 2 of these hands. We 2. Flatt A. Cleft hand and central defects. St. Louis: Mosby, 1977.
3. Manske PR, Halikis MN. Surgical classification of central deficiency 7. Ueba Y. Plastic surgery for the cleft hand. J Hand Surg 1981;6:557–
according to the thumb web. J Hand Surg 1995;20A:687– 697. 560.
4. Hentz VR, Littler JW. Congenital anomalies of the upper extremity. 8. Upton J. Simplicity and treatment of the typical cleft hand. Handchir
In: Converse JM ed. Reconstructive Plastic Surgery. 2nd ed. Phila- Mikrochir Plast Chir 2004;36:152–160.
delphia: WB Saunders and Company, 1977:3306 –3349. 9. Miura T, Komada T. Simple method for reconstruction of the cleft
5. Rider MA, Grindel SI, Tonkin MA, Wood VE. An experience of the hand with an adducted thumb. Plast Reconstr Surg 1979;64:65– 67.
Snow-Littler procedure. J Hand Surg ) 2000;25B:376 –381. 10. Tada K. Central ray deficiency of the hand. Operative treatment and
6. Buck-Gramcko D. Cleft hands: Classification and treatment. Hand results. Int Orthop 1984;8:229 –233.
Clin 1984;1:467– 473. 11. Ogino T. Cleft hand. Hand Clin 1990;6:661– 671.