Running Head: RESPONSES TO PEERS 1
Running Head: RESPONSES TO PEERS 1
Running Head: RESPONSES TO PEERS 1
Responses to Peers
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RESPONSES TO PEERS 2
Responses to Peers
Hi Nadege.
I am really impressed by your enlightening post on factors that influence disease. Although there
are numerous factors that influence diseases, physical examination by a qualified clinician can
help in determining the underlying causes of a disease. In the patient history that you provided,
the patient complained of food poisoning, but was diagnosed with colon cancer. In most cases,
people who suffer from colon cancer complain of abdominal symptoms, which prompt clinicians
to carry out colonoscopy, owing to the suspicion of colon cancer (Vega, Valentín & Cubiella,
2015). CT scan can help in confirming the stage of colon cancer. Although surgery offer the best
option in the treatment of colon cancer in early cases, most patients are only diagnosed when the
disease is in advanced stage (De Rosa et al., 2015). The malignant cells within the adenoma can
be detected early, but it takes quite long to penetrate the submucosa, thus, making hard to detect
References
De Rosa, M., Pace, U., Rega, D., Costabile, V., Duraturo, F., Izzo, P., & Delrio, P. (2015).
Genetics, diagnosis and management of colorectal cancer. Oncology reports, 34(3), 1087-
1096.
Vega, P., Valentín, F., & Cubiella, J. (2015). Colorectal cancer diagnosis: Pitfalls and
Hi Adaeze.
Thank you for your detailed and insightful post on the pathophysiology of hemophilia. Based on
the patient history that you provided, the patient could be had developed hemophilia, and the
The coagulation pathway helps in keeping hemostasis, which is an accumulation of platelets that
develop a plug where endothelial cells have been exposed (Chaudhry & Babiker, 2018).
Two essential patient factors that influence hemophilia are genetics and gender, which are
closely linked through an X-linked recessive pattern. While most cases of hemophilia are
inherited, the genetics of hemophilia affects disease severity, inhibitor development, as well as
preconception testing (Hoots, Shapiro & Heiman, 2019). Having more X chromosomes can help
in preventing hemophilia, as long as there is one normal X chromosome to create clotting factors
after activation.
References
Hoots, W. K., Shapiro, A. D., & Heiman, M. (2019). Genetics of hemophilia A and B.
and-b