Oncology

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EXPLORING FURTHER

Activity 1.4. Complete the table below. List the difference between benign and
malignant neoplasm.

AREA OF COMPARISON BENIGN MALIGNANT

1. Rate of Growth Slow cell growth Rapid cell growth

2. Capsulated Encapsulated Non-capsulated

Usually small, surrounding Often larger, surrounding


3. Expansion
tissues are compressed tissues are invaded,

Capable of metastasis, spreads


Incapable of metastasis, direct
4. Metastasis and migrates to other
extension
organs/systems

Rarely, or does not reoccur Tendency to reoccur when


5. Recurrence
when tumor is removed removed

Often irregular in shape, with


Usually rounded, smooth,
6. Appearance ill-defined borders, lack of
well-defined, corticated
cortication

Does not usually cause tissue


Usually causes extensive
7. Extent of Destruction damage, unless location
tissue and/or organ damage
interferes with blood flow

Does not usually show signs


Present, observed as a
8. Cancer Cachexia of cancer cachexia, depending
frequent complication
on the location of the tumor
Does not cause death, unless Usually causes death due to
9. Death its location interferes with extensive tissue damage and
vital functions of organs spread of tumors

Usually does not need


treatments. If tumor interferes Almost always require
with vital functions of the treatments with surgical
10. Treatment
body or causes problems, removal, radiation therapy, or
patient may need to undergo chemotherapy.
surgical removal.

B. Describe the following and determine if BENIGN or MALIGNANT.

MALIGNANT 1. Teratocarcinoma – A type of germ cell cancer that usually forms in the
testes (testicles). Teratocarcinomas are malignant tumors that, if left
untreated, can lead to mortality due to invasion and metastasis.
BENIGN 2. Nevus - A benign skin growth produced by a cluster of melanocytes (cells
that make a substance called melanin, which gives color to skin and eyes). A
nevus is often black and may protrude from the skin. Also known as a mole.

BENIGN 3. Meningioma - A slow-growing tumor that develops in the meninges (thin


layers of tissue that cover and protect the brain and spinal cord).
Meningiomas are most often found in adults.

BENIGN 4. Adenoma – A benign tumor that begins in gland-like cells of the epithelial
tissue, a thin layer of tissue that covers organs, glands, and other structures
within the body.

BENIGN 5. Dermoid Cyst - A kind of tumor that contains a cyst filled with tissues
typically present in the skin's outer layers, such as sweat and oil glands.
These may also include hair and dental components.

Dermoid cysts can develop anywhere in the body, although they are most
commonly found in the ovary, testes, skin of the head, neck, face, or lower
back, or the central nervous system. Dermoid cysts are noncancerous (not
cancerous) and develop slowly. They exist at birth but may not be discovered
until later in life. Dermoid cysts are a developed teratoma, which is a kind of
germ cell tumor.
References:

Cognito edu.org [Cognito]. (2018, November 27). GCSE Biology - What is Cancer? “Benign”

and “Malignant” Tumours Explained #23 [Video]. YouTube.

https://www.youtube.com/watch?v=B5VHRKBI4PY

Med Today. (2020, November 20). Neoplasia : Benign vs Malignant Tumors, Hallmarks, Spread

& Clinical Manifestations of Cancer [Video]. YouTube.

https://www.youtube.com/watch?v=s5CnwS6QVC8

Merriam-Webster. (2021). Dictionary by. The Merriam-Webster.Com Dictionary.

https://www.merriam-webster.com/

National Cancer Institute. (2021). Comprehensive Cancer Information. https://www.cancer.gov/

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