IB Biology Topic 10 – Genetics HL A3 Revision Sheet

Meiosis Arrange the following chromosomes movements from meiosis in the right order: Annotate the diagram to explain how crossing
over increase variation?
• Homologous chromosomes are _____________________________________________
• Double stranded chromosomes line up on the spindle
• Chiasmata are ____________________________________________
• Homologous chromosomes separate as they move to opposite poles of the cell
• Non-sister chromatids are ____________________________________________ • Centromeres split & single stranded chromosomes more to opposite
• Independent assortment of alleles occurs because of random orientation of ____________ poles of the cell
• During anaphase spindle fibres are responsible for ______________________________
• Pairs of homologous chromosomes form tetrads
• Homologous chromosomes line up on the equator of the spindle
• A difference between meiosis I and meiosis II is _________________________________
• Nuclear membrane forms and four haploid cells are produced.

Dihybrid Inheritance Dihybrid crosses can have 4 x 4 Punnett square. Eg. AaBb x AaBb In a cross between a brown rabbit with
Gene locus (pl. loci) is __________________________________________________________________ AB Ab aB ab long fur and a white rabbit with short
AB AABB AABb fur there were 4 phenotypes of offspring
Unlinked genes segregate independently because they are found on different ______________________
Ab • White short fur
Discrete variation in a phenotype can be identified because there are few __________________________ aB • Brown short fur
ab • White long fur
Continuous variation is when the phenotype varies _______________ or there are many ______________ • Brown long fur
Polygenic characteristics have phenotypes which show continuous _________________________ If one parent is homozygous then one row is enough. AaBb x AABB Which are recombinants, explain why..
AB Ab aB ab _____________________________________
Human height is an example of a AB AABB AABb
AABB only has one possible type of gamete “AB” ____________________________________

Linkage notation Explain why recombinant phenotypes would Chi-squared test can be used to see if there is
Morgan did some crosses with Drosophila flies. He crossed ebony body, scarlet eyed flies (eess) with wild type (genotype EESS) be lower in number than normal mendelian
a significant difference between observed and
Because both the alleles are on chromosome 3 he used “linkage notation” Complete a punnet square using this notation. ratios with linked genes.
expected values. Explain why you have to look
_____________________________________
_____________________________________ up a probability once Χ2 has been calculated?
_____________________________________
Why is it also likely that these will always be ______________________________________
some recombinants, even with linked genes?
_____________________________________ ____________________________________
Recombinant phenotypes would be ____________________________ and ____________________________

Gene pools Compare the 3 methods of reproductive isolation below. • Explain how natural selection can be ‘stabilizing’ Explain how reproductive isolation
leads to speciation?
A “gene pool” is Cause of reproductive How it works. _____________________________________________________________
_____________________________________
_____________________________ isolation ____________________________________________________________
Geographical _____________________________________
____________________________ • Describe what happens in a gene pool exposed to directional selection _____________________________________
Behavioural _____________________________________________________________ _____________________________________
Evolution involves allele frequencies
changing in time. Explain why. ____________________________________________________________ _____________________________________
_____________________________ Temporal
_____________________________ _____________________________________
• What is disruptive selection? ______________________________________