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Pomodoro

The document discusses different treatment options for hyperthyroidism including anion inhibitors like methimazole and propylthiouracil which block thyroid hormone synthesis, iodides which inhibit thyroid hormone release, radioactive iodine which is used when other treatments fail or are contraindicated, and adrenoceptor-blocking agents like propranolol which are commonly used to treat hyperthyroid symptoms.

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12 views

Pomodoro

The document discusses different treatment options for hyperthyroidism including anion inhibitors like methimazole and propylthiouracil which block thyroid hormone synthesis, iodides which inhibit thyroid hormone release, radioactive iodine which is used when other treatments fail or are contraindicated, and adrenoceptor-blocking agents like propranolol which are commonly used to treat hyperthyroid symptoms.

Uploaded by

A H
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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Treatment of hyperthyroidism, primary drug for Grave's

Indications
hyperthyroidism,

Pregnancy and nursing mothers, immune cross


Contraindications
reactivity with propylthiouracil
Anion Inhibitors (Methimazole,
Propylthiouracil) Pharmacokinetics
blocks synthesis of new thyroid hormo
ne;

Maculopapular rash, agranulocytosis, hepatitis,


Side Effects cholestatic jaundice, nausea, GI distress, altered t
aste or smell

Preparation for thyroidectomy or radioactive iodine


Indications
therapy, treatment of thyroid storm

Contraindications Pregnancy and nursing mothers, iodine allergy

Iodides
Inhibits release of thyroid hormone from gland,
Pharmacokinetics
decreases size and vascularity of gland

Metallic taste, salivary gland swelling, rash, iodism


Side Effects
(headache, coryza, conjunctivitis, angioedema)

Antithyroid agent Treatment of hyperthyroidism, primary treatment for


Indications Grave's hyperthyroidism, used when other t
reatments have failed or are contraindicated.

Pregnancy and nursing mothers, severe


Contraindications
ophthalmopathy
Radioactive Iodine
Concentrates in thyroid tissue and destroys thyroid
Pharmacokinetics
cells

Hypothyroidism, radiation sickness, transient


Side Effects
worsening of hyperthyroidism

Propranolol widely studied and used in the therapy of


Indications thyrotoxicosis, beta blockers cause clinical i
mprovement of hyperthyroid symptoms

Contraindications impotence
Adrenoceptor-Blocking Agents
(Metoprolol, Propranolol, Atenolol) Propranolol inhibits 5'-monodeiodinase that converts
L-thyroxine (T4) to triiodothyroni
Pharmacokinetics
ne (T3), competitively blocks both β1 and β2
adrenergic receptors.

Side Effects hypotension ,

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