DAPF Document: Summary of New & Revised CIPAC MT methods status: April 30, 2021 (v1.

1)

CIPAC MT / Title Status CIPAC1 Year of first Comment Replacement for MT’s and / or MT version
Document (Meeting + Year of Publication2 /
no. presentation) Reference3

MT 30.6 Water full 2018 / Revised CIPAC MT 30.5 (Handbook H) is “no longer supported and should
(CIPAC/5154) determination by (Panama 2018) Handbook P method not be used with new specification proposals but remains valid in
Karl Fischer page 222 support of existing specifications.”
method
MT 41.1 Dilution stability of full 2010 / Revised CIPAC MT 41 (Handbook F) is “no longer supported and should not
(CIPAC/4732) aqueous solutions (Ljubljana 2010) Handbook O method be used with new specification proposals but remains valid in
page 174 support of existing specifications.”
MT 46.4 Accelerated full 2019 / Revised CIPAC MT 46.3, MT 46.3.4 LN, MT 46.3.5 MR are “… is no longer
(CIPAC/5217) storage procedure (virtual 2020) Handbook P method supported and should not be used with new specification proposals
page 232 but remains valid in support of existing specifications.”
MT 46.3.4 LN formulations (CIPAC/4956) (Handbook O)
MT 46.3.5 MR formulations (incorporated type) (CIPAC/5045) (full
2017 / Method pre-published on CIPAC homepage only)
MT 47.3 Persistent Foam full 2013 / Revised MT 47.2 (Handbook F) is “no longer supported and should not be
(CIPAC/4835) (Kiew 2013) Handbook O method used with new specification proposals but remains valid in support
page 177 of existing specifications.”
MT 73.1 Total hardness of full 2012 / Additional MT 73 (Handbook F) remains valid and will not be replaced by
(CIPAC/4769) water (Dublin 2012) Handbook O method MT 73.1.
page 179
MT 171.1 Dustiness of full 2015 / Revised MT 171 (Handbook F) is “no longer supported and should not be
(CIPAC/5003) Granular Products (Athen 2015) Handbook P method used with new specification proposals but remains valid in support
page 235 of existing specifications.”
MT 172.2 Flowability of full CIPAC MT 2018 / Revised MT 172.1 (CIPAC/4733 / Handbook O) is “no longer supported and
(CIPAC/5155) Granular (Panama 2018) Handbook P method should not be used with new specification proposals but remains
Preparations after page 241 valid in support of existing specifications.”
Accelerated
Storage under
Pressure

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DAPF Document: Summary of New & Revised CIPAC MT methods status: April 30, 2021 (v1.1)

CIPAC MT / Title Status CIPAC1 Year of first Comment Replacement for MT’s and / or MT version
Document (Meeting + Year of Publication2 /
no. presentation) Reference3

MT 179.1 Degree of full 2014 / Revised MT 179 (Handbook H) is “no longer supported and should not be
(CIPAC/4891) dissolution and (Liege 2014) Handbook O method used with new specification proposals but remains valid in support
solution stability page 189 of existing specifications.”

MT 180 Dispersion full 2012 / Method Extension without new version number
(CIPAC/4794) Stability (Dublin 2012) Handbook O extension Change of scope: Only SE, DC and OD formulations for registration
page 192 / specification with min + max field use concentrations.
Change of Note 1: clarify “screening method”, only for early
development not for registration and quality control.
MT 184.1 Suspensibility full 2019 / Revised MT 184 (Handbook K) is “no longer supported and should not be
(CIPAC//5156) (Braunschweig Handbook P method used with new specification proposals but remains valid in support
2019) page 245 of existing specifications.”
MT 193 Attrition of tablets full 2010 / Revised MT 193 (Handbook L) is “no longer supported and should not be
(CIPAC/4731) (Ljubljana 2010) Handbook O method used with new specification proposals but remains valid in support
page 204 of existing specifications.”
MT 194 Adhesion to full 2009 / Revised MT 83 (Handbook F) & MT 147 (Handbook F) are “no longer
(CIPAC/4580) Treated (El Salvador 2009) Handbook N method supported and should not be used with new specification proposals
Seed page 145 but remains valid in support of existing specifications.”
MT 195 Wash resistance full 2013 / New
(CIPAC/4827) index of LN (Kiew 2013) Handbook O method
page 195
MT 196 Solution full 2012 / New
(CIPAC/4771) Properties of (Dublin 2012) Handbook O method
Water-Soluble page 210
Tablets (ST)
MT 197 Disintegration of full 2014 / New
(CIPAC/4894) tablets (Liege 2014) Handbook O method
page 212

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DAPF Document: Summary of New & Revised CIPAC MT methods status: April 30, 2021 (v1.1)

(1) Status as CIPAC MT (provisional / full), Year and site of CIPAC Meeting where the MT method was first presented.
(2) Year of publication = Year in which the MT method was published on the CIPAC homepage.
(3) Reference = New / revised CIPAC MTs are first published on the CIPAC homepage after the meeting of their presentation during a CIPAC meeting. Only
later, they will be published in a CIPAC Handbook and the respective Handbook is referenced.

Table: List of Handbooks related to CIPAC MT methods & Year of Publication

Handbook Year of Publication

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