Barret's Syndrome Case Report

International Journal of Trend in Scientific Research and Development (IJTSRD)
Volume 7 Issue 1, January-February 2023 Available Online: www.ijtsrd.com e-ISSN: 2456 – 6470
Barret’s Syndrome: Case Report

K Karpagam1, Priyadharshini K2
1
Assistant Professor, Medical Surgical Nursing Department, Saveetha College of Nursing,
2
M.Sc Nursing (Nurse Practioner in Critical Care) II Year, Saveetha College of Nursing,
1,2
Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India
ABSTRACT How to cite this paper: K Karpagam |

Barret's esophagus is a displacement of the squamocolumnar Priyadharshini K "Barret’s Syndrome:
border (SCJ) site to proximal to the gastroesophageal junction Case Report" Published in International
(GEJ) accompanied by the presence of intestinal metaplasia. Also, Journal of Trend in
Scientific Research
it is called as Barret's syndrome or columnar epithelium lined
and Development
lower oesophagus (CELLO).The medical significance of BE is its
(ijtsrd), ISSN:
strong association with esophageal adenocarcinoma , a particularly 2456-6470,
lethal cancer. A 30 year old man presented with complaints of Volume-7 | Issue-1,
heartburn, nausea, vomiting that worsens at times who was February 2023, IJTSRD52704
diagnosed to have bronchitis & sinusitis for 7 years. pp.437-439, URL:
www.ijtsrd.com/papers/ijtsrd52704.pdf
KEYWORDS: Barret's esophagus, squamocolumnar border,
gastroesophageal junction, metaplasia Copyright © 2023 by author (s) and
International Journal of Trend in
Scientific Research and Development
Journal. This is an
Open Access article
distributed under the
terms of the Creative Commons
Attribution License (CC BY 4.0)
(http://creativecommons.org/licenses/by/4.0)
INTRODUCTION Case Description

Barret's esophagus sometimes called barret's A 30 year old man presented with the report of
syndrome or columnar epithelium lined lower heartburn in the chest for 14 years, that frequently
oesophagus (CELLO) is the complication of chronic recurs and sometimes the burning sensation is upto
GERD that is characterized by intestinal metaplasia the larynx. The complaints worsen if he lies flat,
within the esophageal squamous mucosa which is consumes fatty foods or coffee and also had nausea,
defined as the replacement of the normal distal vomiting, bloating and constipation.
stratified squamous mucosa by metaplastic columnar
epithelium containing goblet cells. The incidence is
rising and estimated to occur in as many as 10 % of
individuals with symptomatic GERD.
Fig 1: Normal esophagus vs Barrett’s esophagus
@ IJTSRD | Unique Paper ID – IJTSRD52704 | Volume – 7 | Issue – 1 | January-February 2023 Page 437
International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470
He also had recurring shortness of breath for 7 years and was diagnosed with bronchitis and has a history of
maxillary sinusitis for 7 years. on examination, general condition was moderate, symmetrical chest Wall
movement, no vesicular breathing sounds, increased bowel sounds with unpalpable liver and spleen. In
abdominal ultrasound, a lot of gas found in the intestine\
Fig 2: Normal squamous epithelium VS metaplastic columnar tissue (BE)

In endoscopic examination, a mild patch of hyperemic spots with mucosal break of 7 mm and barret's esophagus
with a length of 2 cm, hyperemia and erythema were found on the antrum of the pylorus.
Fig 3: Histology depicting the difference

The patient was prescribed with medications and lifestyle changes and after 2 weeks of treatment, his condition
improved and was advised to continue the therapy and undergo another endoscopy a year later.
Discussion Conclusion
In barret's esophagus, the tissue lining the esophagus The diagnosis of barret's syndrome requires both
is replaced by tissue that is similar to the lining of the endoscopic evidence of abnormal mucosa above the
intestine which is associated with GERD that is gastroesophageal junction and histologically
diagnosed through an upper gastrointestinal documented intestinal metaplasia. Management of
endoscopy and biopsies. Endoscopic treatments are esophageal dysplasia is evolving and it is hoped that
used to destroy barret's tissue which will hopefully be improved molecular understanding of neoplastic
replaced with normal esophageal tissue. Removal of progression May allow development of chemo
most of the esophagus is recommended if a person preventive approaches that reduces incidence of
with BE is found to have severe dysplasia or Cancer esophageal adenocarcinoma
and can tolerate a surgical procedure.
International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470
Conflict of Interest [2] Colak, Y. erim, T pleskow D. k, barret's
None esophagus; emergency evidence for improved
clinical practice.
Funding
None [3] Muhammad miftahussurur, Iswan Abbas nusi,
Poernomo boedi setiawan, herry purbayu, et al,
Consent for publication
management for a patient with barret's
Informed consent was obtained from the patient to
esophagus; A case report, 438- 445.
publish this case in medical journal.
[4] Spechler SJ, endoscopic surveillance for
References
patients with barret's esophagus does the
[1] Achkar. E, Carey w. The cost of surveillance
Cancer risk justify the practice? Ann intern
for adenocarcinoma complicating barret's
medicine Jun; 902- 904.
esophagus. Am J gastroenterology, mar 23(3);
291-294.

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International Journal of Trend in Scientific Research and Development (IJTSRD)

Barret’s Syndrome: Case Report

ABSTRACT How to cite this paper: K Karpagam |

INTRODUCTION Case Description

Fig 1: Normal esophagus vs Barrett’s esophagus

Fig 2: Normal squamous epithelium VS metaplastic columnar tissue (BE)

Fig 3: Histology depicting the difference

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