Heat Transfer Fluids

Application Pharmaceutical Processing

About Caltherm
Caltherm® is a Caldic brand. Caldic is one of the world’s leading full-service
value-add solution providers for the premium life science and specialty
chemicals markets. Our extensive range of high-quality thermal fluids have
been developed using cutting-edge technology, and are based on the latest
generation of mineral oils, synthetic oils and silicone-based oils.

Offering excellent compatibility

and seamless blending properties,
Caltherm products can be smoothly Why
incorporated into virtually any
processing environment as an choose
alternative or tailor-made heat transfer
fluid. While capable of handling
Caltherm?
temperatures as low as -100 °C up to • Extensive range of high-quality thermal fluids
a high of +400 °C, Caltherm’s reliable • Over 30 years expertise in HTF solutions
solutions fulfill efficiency, operational • Technical expertise on installation and reactivity issue
and safety needs and simultaneously between fluid and manufactured product
address regulatory and environmental • Chemical fluid analysis with on-site testing leading to a
requirements. diagnostic solution
• Thorough pre-cleaning of processing plant to ensure
The Caltherm product range provides maximum effectiveness
solutions for use across processing • Future-proofing approach, including technical needs and
industries, including pharmaceutical, regulatory support
food, chemical, oil & gas, solar power, • Solutions that are tailor-made for you and your challenge
and more. Whatever the set-up of • Alignment with all business units within your company
your processing installation, choosing • Supports financial proposals and investments
one of Caltherm’s solutions, whether • Service-oriented and personal approach
an existing formulation or one • Excellent aftercare services, today, tomorrow,
customized to your situation, will be a and in the future
valuable investment for the future.

Caltherm pharmaceutical processing solutions

Caltherm 400 Caltherm C66 Caltherm CADX10 Caltherm CD12 Caltherm CXP Caltherm S 1050
Fluid for high temperature and low Synthetic fluid for very high temperatu- Synthetic fluid for extreme temperatu- Synthetic fluid for cold and warm Paraffin based fluid for warm system Fluid for high temperature with very
viscosity re application res applications application high flash point

Nature Silicon Nature Synthetic Nature Synthetic Nature Synthetic Nature White minerail oil Nature Silicon
Min Temp °C -40 °C Min Temp °C 0 °C Min Temp °C -45 °C Min Temp °C -85 °C (petroleum) Min Temp °C -50 °C
Max Temp °C 400 °C Max Temp °C 345 °C Max Temp °C 250 °C Max Temp °C 260 °C Min Temp °C 0 °C Max Temp °C 300 °C
Flash Point °C 160 °C Flash Point °C 181 °C Flash Point °C 136 °C Flash Point °C 71 °C Max Temp °C 315 °C Flash Point °C 318 °C
System Closed System Closed System Closed System Closed Flash Point °C 180 °C System Open max 195°C
System Open max 120 °C / Closed
/ Closed
Unique Product Features Unique Product Features Unique Product Features Unique Product Features Unique Product Features Unique Product Features
Possible to use and resistance Possible to use and resistance Possible to use at low and high Possibility to use use at very Possible to use in open system Very high flash point (over the
at high temperatures at high temperatures temperatures low and high temperatures till 120°C use temperatures)
Possible to use at low and atmospheric pression NSF certified Non toxic Possibility to use in open
temperatures system till 195°C
Inert compound Non toxic
Pharmaceutical
Pharma
In 2015, the Caltherm team was
processing approached by a pharmaceutical

application application
manufacturer experiencing technical
issues in their production process

success
originally operating between -30 °C and
The pharmaceutical industry excels at innovation,
delivering high standard, precision solutions. As a result, 160 °C. Following Caltherm’s standard

story
the manufacturing processes are sophisticated and procedures, our specialist determined a
involve phases with high thermal stresses, requiring the
use of reliable, high-quality heat transfer fluids. baseline measurement via an objective
analysis of the incumbent heat transfer
Caltherm’s high-tech thermal fluids are made from
fluid in the pharmaceutical plant. The
mineral, synthetic or silicone products and can replace
glycol mixtures to guarantee the system can handle high outcome of the lab analysis showed that
pressures at high temperatures (for example, 85 bars at
the ten-year-old heat transfer fluid had a
300 °C for water).
degreased flashpoint of 120 °C, compared
The wide range of Caltherm thermal fluids meet to the original 160 °C. This value was
pharmaceutical regulatory requirements by offering fluids
suitable for either very low or very high temperatures not compliant with the regulations of the
(below -80 °C or above 350 °C) or fluids whose versatility pharmaceutical plant.
guarantees permanent efficiency from -50 °C to 300 °C.

After a combination of lab analysis and

site visits to assess the installation, the
Caltherm experts recommended a tailor-
made fluid with an initial viscosity close to
that of the current fluid, but with a higher
flashpoint of 218 °C. They also advised
modifying the position and size of the
expansion tank as it was too small and not
at the highest point of the installation to

Caltherm SY2FC Caltherm SYN FC Caltherm UBT Caltherm UBVI

optimize the systems performances. The
Synthetic fluid for mixt temperatures Synthetic fluid for high temperature Fluid for extrem low temperature Fluid extreme low viscosity at low thorough analysis and expert guidance
application application at very high flash point application temperature and inflammable
ensured the Caltherm solution delivered
Nature Synthetic Nature Synthetic Nature Silicon Nature Silicon long-term optimal performance of the
Min Temp °C -30 °C Min Temp °C -30 °C Min Temp °C -100 °C Min Temp °C -70 °C
customer’s pharmaceutical plant for the
Max Temp °C 300 °C Max Temp °C 350 °C Max Temp °C 270 °C Max Temp °C 200 °C
Flash Point °C 160 °C Flash Point °C 260 °C Flash Point °C 49 °C Flash Point °C 77 °C next 20 years, simultaneously addressing
System Closed System Closed System Closed System Closed
both regulatory and environmental
requirements.
Unique Product Features Unique Product Features Unique Product Features Unique Product Features
Possible to use at low and high Possible to use at low and high Possible to use at extrem low Possible to use at very low
temperatures temperatures temperatures temperatures
NSF certified High flash point Inert compound Inert compound
Non inflammable product
Get in contact
The Caltherm team of technical experts, equipped with longstanding experience across several
industrial sectors, can develop tailor-made solutions to meet specific installation requirements.
Initially, the specialists will determine a baseline measurement via an objective analysis of the HTF
currently used in your system. Following this, the outcomes of the lab analysis, combined with a
site visit to assess the installation, generate a diagnosis which is the starting point to discuss and
recommend a solution that meets your requirements - technical, sustainable, efficient, safety or
cost-effective – today, and in the future.

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CALDIC DEUTSCHLAND GMBH CALDIC IBERICA S.L. CALDIC ITALIA SRL
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Falk Busse Ernest Puch Valentina Castelli

+49 (0) 211 7346 0 +34 93 719 25 61 +39 (0)296 39 01
f.busse@caldic.de ernest.puch@caldic.es castelli.valentina@caldic.it

The Netherlands Sweden Belgium

CALDIC NEDERLAND B.V. CALDIC NORDIC CALDIC BELGIUM N.V.
Westerlaan 1 Frihamnsallén 7 Terlochtweg 1
3016 CK Rotterdam SE-211 20 Malmö B-2620 Hemiksem

Diederik Derksen Peter Feher Jean-Luc Maton

+31 (0)10 4136420 +46 (0)723 69 26 76 +32 (0)3 870 48 11
d.derksen@caldic.nl p.feher@caldic.se jl.maton@caldic.be

France United Kingdom

CALDIC FRANCE S.A.S CALDIC UK LTD. (Chesterfield)
Immeuble le Tropical Stainsby Close
18 Place des Nympéas Holmewood Industrial Estate
Avenue des Nations Chesterfield
C.S. 90005 Villepinte Derbyshire S42 5UG
95926 Roissy Charles de Gaulle
Cedex
Caltherm is a Caldic Brand
Eric Cousinié Mohan Parmar
+33 (0)473 775 575 +44 (0)1246 854111
eric.cousinie@caldic.fr m.parmar@caldic.com