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    Entrez

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    Entrez is a search engine developed by the National Center for Biotechnology Information that allows users to search numerous biomedical and life sciences databases simultaneously. It provides access to PubMed, PubMed Central, GenBank, and other databases containing biomedical literature, gene sequences, protein sequences, and other related information. Entrez was introduced in 1991 and has grown to include additional databases and tools over time. It remains an important resource for researchers, students, and others working in fields related to biotechnology and life sciences.

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    Entrez

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    mcdonald212
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    Entrez is a search engine developed by the National Center for Biotechnology Information that allows users to search numerous biomedical and life sciences databases simultaneously. It provides access to PubMed, PubMed Central, GenBank, and other databases containing biomedical literature, gene sequences, protein sequences, and other related information. Entrez was introduced in 1991 and has grown to include additional databases and tools over time. It remains an important resource for researchers, students, and others working in fields related to biotechnology and life sciences.

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    Entrez is a search engine developed by the National Center for Biotechnology Information that allows users to search numerous biomedical and life sciences databases simultaneously. It provides access to PubMed, PubMed Central, GenBank, and other databases containing biomedical literature, gene sequences, protein sequences, and other related information. Entrez was introduced in 1991 and has grown to include additional databases and tools over time. It remains an important resource for researchers, students, and others working in fields related to biotechnology and life sciences.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    36 views3 pages

    Entrez

    Uploaded by

    mcdonald212
    Entrez is a search engine developed by the National Center for Biotechnology Information that allows users to search numerous biomedical and life sciences databases simultaneously. It provides access to PubMed, PubMed Central, GenBank, and other databases containing biomedical literature, gene sequences, protein sequences, and other related information. Entrez was introduced in 1991 and has grown to include additional databases and tools over time. It remains an important resource for researchers, students, and others working in fields related to biotechnology and life sciences.

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    © All Rights Reserved
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    of 3

    Entrez

    The Entrez (IPA:  [ɒnˈtreɪ])[1] Global Query Cross-Database Search System is a


    federated search engine, or web portal that allows users to search many discrete
    health sciences databases at the National Center for Biotechnology Information
    (NCBI) website.[2] The NCBI is a part of the National Library of Medicine (NLM),
    which is itself a department of the National Institutes of Health (NIH), which in turn
    is a part of the United States Department of Health and Human Services. The name
    "Entrez" (a greeting meaning "Come in" in French) was chosen to reflect the spirit
    of welcoming the public to search the content available from the NLM. The Entrez logo

    Entrez Global Query is an integrated search and retrieval system that provides
    access to all databases simultaneously with a single query string and user interface. Entrez can efficiently
    retrieve related sequences, structures, and references. The Entrez system can provide views of gene and
    protein sequences and chromosome maps. Some textbooks are also available online through the Entrez
    system.

    Features
    The Entrez front page provides, by default, access to the global query. All databases indexed by Entrez can
    be searched via a single query string, supporting Boolean operators and search term tags to limit parts of the
    search statement to particular fields. This returns a unified results page, that shows the number of hits for
    the search in each of the databases, which are also linked to actual search results for that particular database.

    Entrez also provides a similar interface for searching each particular database and for refining search results.
    The Limits feature allows the user to narrow a search a web forms interface. The History feature gives a
    numbered list of recently performed queries. Results of previous queries can be referred to by number and
    combined via Boolean operators. Search results can be saved temporarily in a Clipboard. Users with a
    MyNCBI account can save queries indefinitely and also choose to have updates with new search results e-
    mailed for saved queries of most databases. It is widely used in the field of biotechnology as a reference
    tool for students and professionals alike.

    Databases
    Entrez searches the following databases:

    PubMed: biomedical literature citations and abstracts, including Medline - articles from
    (mainly medical) journals, often including abstracts. Links to PubMed Central and other full-
    text resources are provided for articles from the 1990s.
    PubMed Central: free, full-text journal articles
    Site Search: NCBI web and FTP web sites
    Books: online books
    Online Mendelian Inheritance in Man (OMIM)
    Nucleotide: sequence database (GenBank)
    Protein: sequence database (GenPept)
    Genome: whole genome sequences and mapping
    Structure: three-dimensional macromolecular structures
    Taxonomy: organisms in GenBank Taxonomy
    dbSNP: single nucleotide polymorphism
    Gene:[3] gene-centered information
    HomoloGene: eukaryotic homology groups
    PubChem Compound: unique small molecule chemical structures
    PubChem Substance: deposited chemical substance records
    Genome Project: genome project information
    UniGene: gene-oriented clusters of transcript sequences
    CDD: conserved protein domain database
    PopSet: population study data sets (epidemiology)
    GEO Profiles: expression and molecular abundance profiles
    GEO DataSets: experimental sets of GEO data
    Sequence read archive: high-throughput sequencing data
    Cancer Chromosomes: cytogenetic databases
    PubChem BioAssay: bioactivity screens of chemical substances
    Probe: sequence-specific reagents
    NLM Catalog: NLM bibliographic data for over 1.2 million journals, books, audiovisuals,
    computer software, electronic resources, and other materials resident in LocatorPlus
    (updated every weekday).

    Access
    In addition to using the search engine forms to query the data in Entrez, NCBI provides the Entrez
    Programming Utilities[4] (eUtils) for more direct access to query results. The eUtils are accessed by posting
    specially formed URLs to the NCBI server, and parsing the XML response. There was also an eUtils
    SOAP interface which was terminated in July 2015.[5]

    History
    In 1991, Entrez was introduced in CD form. In 1993, a client-server version of the software provided
    connectivity with the internet. In 1994, NCBI established a website, and Entrez was a part of this initial
    release. In 2001, Entrez bookshelf was released and in 2003, the Entrez Gene database was developed.[6]

    References
    1. "Definition of 'entrez' " (https://www.collinsdictionary.com/dictionary/english/entrez/). Collins
    Dictionary [Internet].
    2. NCBI Resource Coordinators (2012). "Database resources of the National Center for
    Biotechnology Information" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531099).
    Nucleic Acids Research. 41 (Database issue): D8–D20. doi:10.1093/nar/gks1189 (https://do
    i.org/10.1093%2Fnar%2Fgks1189). PMC 3531099 (https://www.ncbi.nlm.nih.gov/pmc/article
    s/PMC3531099). PMID 23193264 (https://pubmed.ncbi.nlm.nih.gov/23193264).
    3. "Home - Gene - NCBI" (https://www.ncbi.nlm.nih.gov/gene/).
    4. Entrez Utilities (https://www.ncbi.nlm.nih.gov/entrez/query/static/eutils_help.html). National
    Center for Biotechnology Information (US). 2010.
    5. The E-utility Web Service (SOAP) (https://www.ncbi.nlm.nih.gov/books/NBK43082/).
    National Center for Biotechnology Information (US). 23 January 2015.
    6. Smith, Kent. "A Brief History of NCBI's Formation and Growth" (https://www.ncbi.nlm.nih.gov/
    books/NBK148949/). The NCBI Handbook [Internet]. 2nd edition. Retrieved 3 May 2014.

    External links
    Entrez search engine form (https://www.ncbi.nlm.nih.gov/sites/gquery)
    Entrez Help (https://www.ncbi.nlm.nih.gov/books/NBK3836/)

    Retrieved from "https://en.wikipedia.org/w/index.php?title=Entrez&oldid=1166945032"

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