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CRISPR Infographic

CRISPR-Cas9 is a genetic engineering tool that edits genes. It works by using a guide RNA to bind to a target sequence of DNA. The Cas9 complex then cuts both strands of DNA at that location. This allows for targeted editing of the genome. While CRISPR has a high success rate of around 97%, there is debate about using it to edit reproductive cells due to concerns about passing on heritable genetic changes.

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Santino Dev Joseph Xavier (Sji)
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118 views1 page

CRISPR Infographic

CRISPR-Cas9 is a genetic engineering tool that edits genes. It works by using a guide RNA to bind to a target sequence of DNA. The Cas9 complex then cuts both strands of DNA at that location. This allows for targeted editing of the genome. While CRISPR has a high success rate of around 97%, there is debate about using it to edit reproductive cells due to concerns about passing on heritable genetic changes.

Uploaded by

Santino Dev Joseph Xavier (Sji)
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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CRISPR

CAS 9
By santino Dev
MN302

HOW IT
WORKS:
2 Guide RNA CRISPR short for
binds to target
9
Clustered Regularly
n C as NA sequence
te i R Interspaced Short
p ro
9 gle Cas 9 complex Palindromic Repeat
Cas s in
an d a
R N A
to 4 cuts of both
id e ds
gu bin
t he strands of DNA
e m ng
1 n zy m i DNA
e for ex
s 9 NA pl
Ca R om
id e 9 c
gu a s
C
3
Cas 9

RNA The problem with


this is that any changes
made in reproductive cells
Many of the will be passed on from
genomes involve generation
Targeted editing of non-reproductive
i o n
sequence cells ne r a t
ge
n

97%
i o
CRISPR is used as a he p ot en ti al ra t
debate about t e n e
g
genetic engineering eprodu ctiv e c el ls
to edit r
success rate, of challenging
tool that edits a gene's
projects
base pairs using a DNA
sequence and its 70
projects completed up to date
associated protein.
References Leukemia Diagnostics
(n.d.). Gene-editing. Horizon Discovery. Distribution of Solid Tumour Metabolic
https://horizondiscovery.com/en/gene-
editing?gad=1&gclid=EAIaIQobChMIlduru- gene-editing Disease
_2_wIV75pmAh1CVAL8EAAYASAAEgJy
trials for disease Sickle cell Other rare
disease Diseases
& diagnostics.
(n.d.). CRISPR data. CRISPR Medicine News.
https://crisprmedicinenews.com/news/crisp
r-medicine-in-2021-what-a-phenomenal- HIV Haemophilia
year-of-firsts/

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