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    Brochure FlowLine Bipore HEPARIN (EN)

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    Tuyen nguyen ngoc

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    © All Rights Reserved
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    Brochure FlowLine Bipore HEPARIN (EN)

    Uploaded by

    Tuyen nguyen ngoc
    99 views4 pages

    Copyright

    © © All Rights Reserved

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    PDF, TXT or read online from Scribd

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    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    99 views4 pages

    Brochure FlowLine Bipore HEPARIN (EN)

    Uploaded by

    Tuyen nguyen ngoc

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 4

    FlowLine Bipore® HEPARIN

    ePTFE Vascular Graft with Heparin Coating


    FlowLine Bipore® HEPARIN
    ePTFE Vascular Graft with Heparin Coating

    Thromboresistant lumen surface for increased graft patency


    Covalent bonding and ionic interactions binds Heparin durable to the lumen surface of the FlowLine
    Bipore® HEPARIN graft. This innovative bonding technique imitates the antithrombogenic effect of the
    natural endothelium and leads to increased hemocompatibility.

    Dynamic blood tests Thrombocytes [ x10³/ ]


    Level of hemocompatibility 400

    350

    300
    Control
    250

    Uncoated ePTFE grafts 200

    150
    FlowLine Bipore® HEPARIN 100

    50

    Trial 1 Trial 2 Trial 3

    Dynamic blood tests confirm high level of hemocompatibility¹


    The number of free thrombocytes in blood being In uncoated ePTFE grafts there is a decrease in the
    exposed to the lumen of FlowLine Bipore® HEPARIN number of free platelets due to thrombus formation on
    is comparable to the control group. the lumen surface.

    The microscopic image clearly illustrates the advantage of the FlowLine Bipore® HEPARIN grafts over
    uncoated ePTFE grafts.

    Uncoated ePTFE graft: FlowLine Bipore® HEPARIN:


    Thrombus formation after 2 hours of blood contact 1 Significantly reduced platelet adhesion1

    1
    In vitro studies / dynamic blood test in Chandler Loop by Dr. H.P. Wendel:
    Clinical Research Laboratory, Clinic for Thoracic, Cardiac and Vascular Surgery, University Hospital Tübingen
    Unique guideline indicating graft diameter and wall thickness The external reinforcement can easily be removed if required

    FlowLine Bipore® HEPARIN provides better patient care


    Excellent and pliable handling and suture behaviour
    Additional ePTFE wrap for enhanced suture retention and high burst strength
    Helical reinforcement ensuring high kinking and compression resistance

    The proven alternative with sustained antithrombogenic effect


    This results from a prospective, open label, randomised multicentre study comparing
    FlowLine Bipore® HEPARIN with uncoated ePTFE grafts. More tha n 500 patients were
    enrolled and randomised to 6mm, reinforced FlowLine Bipore® HEPARIN and
    uncoated ePTFE grafts.

    Primary Patency %
    AK bypasses
    100
    1 year: 84% 2 years: 80%
    FlowLine Bipore HEPARIN
    ®

    80
    Uncoated ePTFE grafts
    60
    P: 0,01 HR: 1,70 1 year: 77% 2 years: 63%
    40

    20

    Time (Days)

    200 400 600 800

    „... there is a significant difference [...] in favour of the FlowLine Bipore HEPARIN grafts.“
    Prof. Frank Vermassen, MD, University Hospital Gent
    Vascular News July 2009
    FlowLine Bipore® HEPARIN
    ePTFE Vascular Graft with Heparin Coating

    Ordering information
    Quick and reliable delivery of standard products in Europe within 24 hours.
    Call our central office: +49 (0) 7471 / 922-0

    Thin Wall with


    Thin Wall spiral reinforcement
    Length Diameter
    Catalogue No. Catalogue No.
    (cm) (mm)
    40 5 15TW4005N 15TW4005S
    50 6 15TW5006N 15TW5006S
    50 7 15TW5007N 15TW5007S
    50 8 15TW5008N 15TW5008S
    70 5 15TW7005N 15TW7005S
    80 6 15TW8006N 15TW8006S
    80 7 15TW8007N 15TW8007S
    80 8 15TW8008N 15TW8008S

    Standard Wall with


    Standard Wall spiral reinforcement
    Length Diameter
    Catalogue No. Catalogue No.
    (cm) (mm)
    20 6 15SW2006N –
    20 7 15SW2007N –
    40 5 15SW4005N –
    50 6 15SW5006N 15SW5006S
    50 7 15SW5007N 15SW5007S
    50 8 15SW5008N 15SW5008S
    70 5 15SW7005N –
    80 6 – 15SW8006S
    80 7 – 15SW8007S
    80 8 – 15SW8008S

    2011 JOTEC GmbH, Germany. All rights reserved. 2011/11-3.2

    JOTEC AG JOTEC GmbH JOTEC s.r.l.


    Luzernerstr. 91 Lotzenäcker 23 Vicolo Valtellina n.15
    CH-5630 Muri D-72379 Hechingen I-20092 Cinisello Balsamo (Mi)
    T +41 (0)  56  670  91 - 00 T +49 (0) 74 71 / 922 - 0 T +39 02 91090491
    F +41 (0)  56  670  91 - 02 F +49 (0)  74 71 / 922 - 100 F +39 02 66014455

    JOTEC CARDIOVASCULAR SL JOTEC Polska Sp. z o.o.


    ©

    Av. Castilla 2, P. E. San Fernando ul. Pory 78


    Edificio Italia – planta baja PL-02-757 Warszawa
    E-28830 S. Fernando de Henares (Madrid) T +48 (0) 22 456 19 69
    T +34 (0)  91 - 648  70  20 F +48 (0) 22 456 18 99
    www.jotec.com F +34 (0)  91 - 656  17  73

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