Ventricular septal defect is a cardiac anomaly where there are openings between the left and right ventricles through the septum. It can occur in different locations of the septum and be associated with other cardiac defects. Symptoms depend on the size of the opening and amount of blood shunting between the ventricles. Imaging such as echocardiogram, CT, and MRI are used to diagnose and characterize the location and size of the defect.
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Ventricular septal defect is a cardiac anomaly where there are openings between the left and right ventricles through the septum. It can occur in different locations of the septum and be associated with other cardiac defects. Symptoms depend on the size of the opening and amount of blood shunting between the ventricles. Imaging such as echocardiogram, CT, and MRI are used to diagnose and characterize the location and size of the defect.
• Cardiac anomaly with communication(s) between left & ○ Shunt volume estimated by velocity encoded cine MR right ventricles through septum imaging ○ Perimembranous septal defect (80%) TOP DIFFERENTIAL DIAGNOSES ○ Posterior or inlet defect associated with atrioventricular • Atrioventricular canal defects septal defect (AVSD) (8-10%) • Patent ductus arteriosus ○ Muscular or trabecular septal defect (5-10%) • Double outlet right ventricle ○ Outlet septal defect or supracristal ventricular septal defect (VSD) (5%) CLINICAL ISSUES • Complex cardiac anomalies with VSD: TOF, truncus, DORV • Small VSD: Children asymptomatic but have heart murmur IMAGING ○ May close spontaneously • Moderate or large shunts often asymptomatic early until • Cardiomegaly with ↑ size of main pulmonary artery, ↑ pulmonary vascular resistance drops pulmonary artery flow, left atrial enlargement, & usually ○ Children develop tachypnea, tachycardia, diaphoresis, & small aorta failure to thrive • Hyperinflation in large shunts from abnormal lung ○ Treated medically with subsequent surgical approach compliance & bronchial compression by dilated pulmonary arteries – Muscular lesions require more difficult surgical approach; VSD catheter closure devices often used • CT & MR delineate anatomy
(Left) Axial SSFSE T2 fetal MR
shows a perimembranous-type ventricular septal defect (VSD) ſt in this fetus with tetralogy of Fallot. (Right) Three- chamber view from a cine sequence cardiac MR shows an aneurysm of the membranous ventricular septum protruding into the right ventricle. This likely represents the spontaneous membranous closure of a previously patent VSD. When large, the aneurysm may cause right ventricular outflow tract obstruction.
(Left) Frontal radiograph of
the chest shows cardiomegaly with increased pulmonary vascularity in a patient with multiple intramuscular-type VSDs. Multiple VSD closure devices have been placed in an attempt to decrease shunting. (Right) Oblique axial cardiac CTA shows a Swiss cheese appearance of the interventricular septum st near the apex in this patient with multiple muscular-type VSDs. Notice the normal positions of the septum .