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PHARMACEUTICS

1. The document outlines the curriculum for a Pharmaceutics theory and practical course, including 50 hours of theory and 75 hours of practical work. 2. The theory section will cover topics like pharmaceutical dosage forms, weights and measures, prescription handling, and incompatibility. The practical section lists 14 experiments involving preparations like syrups, suspensions, emulsions, and semisolids. 3. Evaluation of students will include a synopsis, major experiments, minor experiments, and viva voce, with a total of 70 marks. Reference books and minimum laboratory equipment are also provided.

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203 views

PHARMACEUTICS

1. The document outlines the curriculum for a Pharmaceutics theory and practical course, including 50 hours of theory and 75 hours of practical work. 2. The theory section will cover topics like pharmaceutical dosage forms, weights and measures, prescription handling, and incompatibility. The practical section lists 14 experiments involving preparations like syrups, suspensions, emulsions, and semisolids. 3. Evaluation of students will include a synopsis, major experiments, minor experiments, and viva voce, with a total of 70 marks. Reference books and minimum laboratory equipment are also provided.

Uploaded by

pranavi
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© © All Rights Reserved
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1.

2 PHARMACEUTICS (THEORY)
50 hours ; 2 hours/week
1. Historical background and development of profession of pharmacy.
Development of Indian pharmacopoeia and introduction to other pharmacopoeias
such as B.P, U.S.P, European pharmacopoeia, Extra pharmacopoeia and Indian
National Formulary. 4 hours; 6-8 marks
2. Weights and measures: Different types of weights and measures, modern methods of
weighing, errors in weighing. Calculations involving percentage of solutions,
allegation method, proof sprit, isotonic solutions. 4 hours; 6-8 marks
a) Prescription: Definition, parts of prescription, handling and sources of errors.
b) Posology: Definition, factors affecting dose selection, calculation of child and
infant doses.
c) Incompatibility: Introduction to physical and chemical incompatibility. Discussion
of therapeutic incompatibility with examples. 5 hours; 8-10 marks
3. Introduction to dosage forms: Classification and definitions. Theoretical aspects
including commonly used vehicles, essential adjuvants like stabilizers, colorants and
flavourants with relevance to monophasic liquid dosage forms. 6 hours; 10-12 marks

4. Biphasic liquid dosage forms:


1. Suspensions: Definition, classification, advantages and disadvantages. Study of
diffusible and in-diffusible solids, flocculated and deflocculated suspension.
Settling in suspension, discussion on wetting, controlled flocculation and
flocculation in structured vehicles.
2. Emulsions: Definition, classification and identification of types of emulsion,
mechanism of action of emulsifying agents, theories of emulsification. Formulation
of emulsion; stability of emulsions. 8 hours; 13-15 marks

5. Powders and granules: Classification, advantages and disadvantages and methods of


mixing of powders. Preparation of simple powders, compound powders, insufflations,
dusting powders, Eutectic powders. Study of effervescent granules.4hours;6-8 marks

6. Semi solid dosage forms: Definition, types, semi-solid bases, their selection.
Formulation of semi solids such as ointments, creams, pastes, gels, suppositories,
packaging, and their evaluation. 8 hours; 13-15 marks

7. Galenicals: Definition of infusion, decoction and expression. Detailed study of


maceration and percolation and Soxhlet extraction. 4 hours; 6-8 marks

8. Surgical Aids: Study of surgical dressings namely bandages, absorbent cotton and
POP. Definition and types of surgical sutures and ligatures. Manufacturing,
standardization and sterilization of surgical catgut. 4 hours; 6-8 marks

9. Radiopharmaceuticals: Uses in diagnosis and treatment, methods of preparations,


handling and safety precautions. 3 hours; 5-7 marks
PHARMACEUTICS (PRACTICALS)
75 Hours ; 3 hours/week
1. Syrups:
a) Simple syrup IP *
b) Syrup of ephedrine hydrochloride NF*
2. Elixirs:
a) Piperazine citrate elixir BP*
b) Paracetamol paediatric elixir BPC*
3. Linctuses:
a) Simple linctus BPC*
b) Paediatric compound tolu linctus*
4. Solutions:
a) Solution of cresol with soap IP**
b) Aqueous iodine solution IP*
c) Strong ammonium acetate solution IP**
5. Galenicals:
a) Tincture of benzoin*
b) Spirit of camphor USP*
6. Gargle:
a) Potassium chlorate gargle*
7. Mouth wash:
a) Antiseptic mouth wash*
8. Enema:
a) Glycerin enema*
9. Liniments:
a) Liniment of turpentine IP**
b) Liniment of camphor BPC**
10.Lotions:
a) Calamine lotion IP**
b) Benzyl benzoate lotion USP*
11.Suspensions:
a) Magnesium hydroxide mixture BP**
b) Preparation of deflocculated and flocculated suspensions and their
evaluation**
12.Emulsions:
a) Cod liver oil emulsion**
b) Liquid paraffin emulsion. Preparation and evaluation**
13.Powders:
a) Eutectic powder*
b) Dusting powder*
c) Effervescent granules**
14.Semi solids:
a) Simple ointment*
b) Zinc and Salicylic acid paste*
c) Diclofenac gel**
d) Boric acid suppository**
e) Lactic acid pessaries**
Note: ** Denotes major experiments * Denotes minor experiments
SCHEME OF EXAMINATION

1. Synopsis -10 Marks


2. Major experiment (indicated by **) -30 Marks
3. Minor experiment (indicated by *) -20 Marks
4. Viva voce -10 Marks
Total =70 Marks

PHARMACEUTICS REFERENCE BOOKS

1. Aulton ME. Pharmaceutics, The science of dosage form design. 2 nd ed.


Edinburgh:Churchill Livingstone;2002.
2. Bharat S. Pharmaceutics. New Delhi:Dorling Kindersley (India) Pvt Ltd;2013.
3. British Pharmacopoeia (BP), United States Pharmacopoeia (USP), Extra
Pharmacopoeia, Merck Index, and British Pharmaceutical Codex (BPC).
4. Carter SJ. Cooper and Gunn's Dispensing for pharmaceutical students. 12th ed.
New Delhi:CBS Publishers;2000.
5. Carter SJ. Cooper and Gunn’s Tutorial pharmacy. 6th ed. New Delhi:CBS
Publishers;2000.
6. Gennaro AL. Remington: The science and practice of pharmacy, Vol I and II. 20th
ed. Philadelphia:Lippincott Williams and Wilkns;2000.
7. Indian Pharmacopoeia. Delhi:The Controller of Publications;1966, 1977, 1985,
1996, 2007, 2014.
8. Loyd VA, Nicholas GP, Howard CA. Ansel’s pharmaceutical dosage forms and
drug delivery systems. 8th ed. Noida: BI Publications Pvt Ltd;2005.
9. Mehta RM. Dispensing Pharmacy. Delhi:Vallabh Prakashan;2013.
10. Mehta RM. Pharmaceutics I. Delhi:Vallabh Prakashan;2014.
11. Mitchell JS, Howard CA. Pharmaceutical calculations. 10th ed. New Delhi:BI
Waverley Pvt Ltd;1996.
12. Rawlins EA. Bentley’s textbook of pharmaceutics. 8th ed. New Delhi:Reed
Elsevier India Pvt Ltd;2010.
13. Subrahmanyam CVS. Textbook of physical pharmaceutics. 2nd ed. Delhi:Vallabh
Prakashan;2003.

LIST OF MINIMUM EQUIPMENTS REQUIRED

1. Electronic balances 02 nos.


2. Homogeniser 02 nos.
3. Mechanical stirrers 10 nos.
4. Oven 01 no.
5. pH meter 01 no.
6. Suppository moulds 20 nos.

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