NAME: RODAS, EVELYN EDLENE JOY P.

DATE: SEPTEMBER 7, 2022

GROUP AND SECTION: BSN3E - A NAME OF CI: GOMER P. PONSO

DRUG NAME MECHANISM OF ACTION INDICATION/ ADVERSE EFFECTS NURSING RESPONSIBILITIES

CONTRAINDICATION
GENERIC: Cefuroxime Binds to penicillin-binding INDICATION/S: CNS: seizures (high doses) BEFORE
proteins and inhibits the final Treatment of Respiratory tract • Verify patient.
BRAND: Ceftin transpeptidation step of infections, Skin and skin structure GI: pseudomembranous colitis, • Observe the rights of administrations.
peptidoglycan synthesis, infections, Bone, and joint infections diarrhea, nausea, vomiting, cramps. • Check for allergies.
THERAPEUTIC: Anti- resulting in cell-wall death; (IV), Urinary tract infections, • Assess vital signs.
Infectives resists degradation by beta- Gynecologic infections, Septicemia Derm: rashes, urticaria, diaper • Educate the patient about the drug.
lactamase; proper dosing and (IV), Otitis media (PO), Meningitis dermatitis.
PHARMACOLOGIC: appropriate route of (IV), Lyme disease (PO). Perioperative DURING
Second-Generation administration are determined prophylaxis Hemat: bleeding, eosinophilia,
Cephalosporins hemolytic anemia, leukopenia.
by the condition of the patient, • Monitor for adverse reactions.
the severity of infection, and • Observe/monitor the patient from time to
DOSAGE: 500mg Local: pain at IM site, phlebitis at the
susceptibility of the CONTRAINDICATION/S: time.
IV site.
ROUTE: Oral microorganism. • Encourage the patient to verbalize feelings
CEFTIN is contraindicated in patients Misc: allergic reactions including and concerns.
with known hypersensitivity (e.g., anaphylaxis, superinfection.
anaphylaxis) to CEFTIN or other β- AFTER
lactam antibacterial drugs (e.g., • Assess vital signs.
penicillin and cephalosporins). • Assess for any adverse reactions.
• Encourage the patient to immediately
report any untoward reactions to the
physician/nurse.

DRUG NAME MECHANISM OF ACTION INDICATION/CONTRAINDICATION ADVERSE EFFECTS NURSING

RESPONSIBILITIES
GENERIC: Ketorolac Ketorolac inhibits key pathways in INDICATION/S: CNS: drowsiness, abnormal BEFORE
 prostaglandin synthesis which is thinking, dizziness, euphoria, • Verify patient.
BRAND: Toradol crucial to its mechanism of Used to treat moderate to severe pain, headache. • Check for allergies.
action.4 Although ketorolac is rheumatoid arthritis, osteoarthritis, • Assess vital signs.
THERAPEUTIC: non-selective and inhibits both ankylosing spondylitis, menstrual Resp: asthma, dyspnea. • Assess pain scale.
Non-steroidal Anti-inflammatory COX-1 and COX-2 enzymes, its disorders, and headaches. • Educate the patient about the
agents, nonopioid analgesics clinical efficacy is derived from its CV: edema, pallor, vasodilation. drug.
COX-2 inhibition. The COX-2
enzyme is inducible and is CONTRAINDICATION/S: GI: GI BLEEDING, abnormal DURING
PHARMACOLOGIC: responsible for converting TORADOL is contraindicated in patients taste, diarrhea, dry mouth,
pyrrolizine carboxylic acid arachidonic acid to prostaglandins with previously demonstrated dyspepsia, GI pain, nausea. • Monitor for adverse reactions.
that mediate inflammation and hypersensitivity to ketorolac • Observe/monitor the patient from
pain. By blocking this pathway, tromethamine, is contraindicated in GU: oliguria, renal toxicity, time to time.
DOSAGE: 30mg/mL ketorolac achieves analgesia and patients with active peptic ulcer disease, urinary frequency. • Encourage the patient to
reduces inflammation.3 Ketorolac in patients with recent gastrointestinal verbalize feelings and concerns.
is administered as a racemic bleeding or perforation and patients with a Derm: exfoliative dermatitis,
ROUTE: IV mixture; however, the "S" history of peptic ulcer disease or steven-Johnson syndrome, toxic AFTER
enantiomer is largely responsible gastrointestinal bleeding, should not be epidermal necrolysis, pruritus, • Assess vital signs.
for its pharmacological activity. given to patients who have experienced purpura, sweating, urticaria. • Assess for any adverse reactions.
asthma, urticaria, or allergic-type • Assess if there are any changes in
reactions after taking aspirin or other Hemat: prolonged bleeding time. the pain scale to determine the
NSAIDs. Severe, rarely fatal, effectiveness of the drug.
anaphylactic-like reactions to NSAIDs Local: injection site pain. • Encourage the patient to
have been reported in such patients, immediately report any untoward
Toradol is contraindicated as a Neuro: paresthesia. reactions to the physician/nurse.
prophylactic analgesic before any major
surgery, for the treatment of peri-operative Misc: allergic reactions,
pain in the setting of coronary artery including, anaphylaxis.
bypass graft (CABG) surgery, patients
with advanced renal impairment or in
patients at risk for renal failure due to
volume depletion for correction of volume
depletion), in labor and delivery because,
through its prostaglandin synthesis
inhibitory effect, it may adversely affect
fetal circulation and inhibit uterine
contractions, thus increasing the risk of
uterine hemorrhage. Toradol inhibits
platelet function and is, therefore,
contraindicated in patients with suspected
or confirmed cerebrovascular bleeding,
hemorrhagic diathesis, incomplete
hemostasis, and those at high risk of
bleeding (see WARNINGS and
PRECAUTIONS), and patients currently
receiving aspirin or NSAIDs because of
the cumulative risks of inducing serious
NSAID-related adverse events.