

cobas® 6500
urine analyzer series

Host Interface Manual

Version 2
Host Interface Manual cobas 6500 urine analyzer series

Table of Contents
1 Preface .....................................................................................................................................................4
1.1 Manual information ...........................................................................................................................4
1.1.1 Revision history .............................................................................................................................4
1.1.2 Editor’s noted .................................................................................................................................4
1.1.3 Copyrights .......................................................................................................................................4
1.1.4 Brands ..............................................................................................................................................4
1.1.5 Contact addresses........................................................................................................................4
1.2 Using this manual .............................................................................................................................4
1.3 Conventions used in this manual .................................................................................................4
1.3.1 Symbols ...........................................................................................................................................5
1.3.2 Abbreviations..................................................................................................................................5
1.4 Safety classification ..........................................................................................................................5
2 Introduction .............................................................................................................................................6
2.1 Overview ..............................................................................................................................................6
2.1.1 Purpose and scope ......................................................................................................................6
2.1.2 Audience ..........................................................................................................................................6
2.2 System overview ...............................................................................................................................6
2.2.1 cobas u 601 urine analyzer ........................................................................................................6
2.2.2 cobas u 701 microscopy analyzer ...........................................................................................6
2.2.3 Topology ..........................................................................................................................................6
2.2.4 LIS communication .......................................................................................................................7
3 Sample processing ...............................................................................................................................8
3.1 Identifying samples on the instrument ........................................................................................8
3.1.1 Barcode and sample ID’s ...........................................................................................................8
3.1.2 Samples missing a barcode ......................................................................................................8
3.1.3 Controls missing a barcode .......................................................................................................8
3.1.4 Sequence numbers ......................................................................................................................8
3.2 Querying orders to the host ...........................................................................................................8
3.3 Returning results to the host..........................................................................................................9
3.3.1 Result and Raw data transmission u601 ...............................................................................9
3.3.2 Result and Raw data transmission u701 and c6500....................................................... 10
3.4 Particle configuration .................................................................................................................... 12
3.5 Image transmission u701 and c6500 ....................................................................................... 14

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3.5.1 Microscope images ................................................................................................................... 14

3.5.2 Map network drive ..................................................................................................................... 15
3.5.3 Image transfer configuration ................................................................................................... 16
3.6 Passing results automatically to the host ............................................................................... 17
3.7 Communication types ................................................................................................................... 18
3.7.1 Communication and message types .................................................................................... 18
3.7.2 Communication scenarios ....................................................................................................... 18
3.7.3 Details of message types ........................................................................................................ 18
4 Interface description .......................................................................................................................... 19
4.1 Host communication settings ..................................................................................................... 19
4.1.1 Communication setup ............................................................................................................... 19
4.1.2 Host communication check ..................................................................................................... 20
4.2 Physical layer specifications ....................................................................................................... 25
4.2.1 Electrical Characteristics ......................................................................................................... 25
4.2.2 Mechanical Characteristics ..................................................................................................... 26
5 ASTM Reference................................................................................................................................ 27
5.1 ASTM protocol (LIS2 – A2) ......................................................................................................... 27
5.1.1 Background .................................................................................................................................. 27
5.1.2 Communication Processing Layers ...................................................................................... 27
5.1.3 ASTM Lower Layer .................................................................................................................... 27
5.1.4 ASTM syntax ............................................................................................................................... 27
5.2 ASTM text content (LIS2 – A2) .................................................................................................. 29
5.2.1 Record levels............................................................................................................................... 29
5.2.2 Messages used in host communication .............................................................................. 30
5.2.3 Record description..................................................................................................................... 31
5.2.4 Message Header Record......................................................................................................... 32
5.2.5 Patient Information Record ..................................................................................................... 33
5.2.6 Test Order Record ..................................................................................................................... 35
5.2.7 Result Record ............................................................................................................................. 36
5.2.8 Comment Record (following Result Record) ..................................................................... 38
5.2.9 Request Information Record .................................................................................................. 39
5.2.10 Message Termination Record ............................................................................................ 39
5.2.11 Manufacturer Information Record ..................................................................................... 40
6 Appendices .......................................................................................................................................... 45
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6.1 Data Alarms ..................................................................................................................................... 45

6.2 Test number and Test code of u 601 ....................................................................................... 46
6.3 Test number and Test code of u 701 ....................................................................................... 46
6.4 Communication examples ........................................................................................................... 47
6.4.1 Host protocol version 8 ............................................................................................................ 47
6.4.2 Host protocol version 9 ............................................................................................................ 54

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1 Preface
1.1 Manual information
1.1.1 Revision history
Manual version Software version Revision date Remark
1 2.2.0 22-Jul-2015 First version
2 2.2.1 09-Feb-2016 Chapter Host Communication Check:
WinMonitor removed

1.1.2 Editor’s noted

Every effort has been made to ensure that all the information contained in this manual is correct at the time of
printing. However, Roche Diagnostics International Ltd reserves the right to make any changes necessary
without notice as part of ongoing product development. Any customer modification to the instrument will
render the warranty or service agreement null and void.

1.1.3 Copyrights
© 2013, Roche Diagnostics International Ltd. All rights reserved. The contents of this document may not be
reproduced in any form or communicated to any third party without the prior written consent of Roche.
While every effort is made to ensure its correctness, Roche assumes no responsibility for errors or
omissions which may appear in this document. Subject to change without notice.

1.1.4 Brands
COBAS, COBAS U, and LIFE NEEDS ANSWERS are trademarks of Roche.

1.1.5 Contact addresses

Manufacturer
Roche Diagnostics GmbH
Sandhofer Strasse 116
68305 Mannheim, Germany

Made in Hungary
www.roche.com

1.2 Using this manual

NOTICE Keep this manual in a safe place to ensure that it is not damaged and remains available for use.
This host interface description should be easily accessible at all times.

Related documents:
 LIS01-A2: Specification for Low-Level Protocol to Transfer Messages between Clinical Laboratory
Instruments and Computer Systems.
 LIS2-A2: Specification for Transferring Information between Clinical Laboratory Instruments and
Information Systems.

1.3 Conventions used in this manual

The following chapters describe the conventions used in this manual, such as safety symbols, safety
classification and abbreviations. Do not proceed reading this manual before these chapters have been read
and understood.

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1.3.1 Symbols
Symbols are used to help quickly locate and interpret information in this manual. This section explains the
formatting conventions used in this manual.

The following symbols are used:

Symbol Description

The tip symbol indicates additional information on

correct use of the analyzer or useful tips

Safety alert symbol

1.3.2 Abbreviations
The following abbreviations are used:

Abbreviation Definition
A
ASTM American Society for Testing and
Material
C
c6500 cobas 6500 analyzer series
D
DNS Domain Name Server
L
LIS Laboratory Information System
U
u601 cobas u 601 urine analyzer
u701 cobas u 701 microscopy analyzer

1.4 Safety classification

Safety messages are classified according to ANSI Z535.6. The following classifications are used, according
to the level of seriousness of the hazard: The safety alert symbol by itself (without a signal word) is used to
promote awareness to hazards which are generic or to direct the reader to safety information provided
elsewhere in the document. The following signal words are used for specific hazards:

WARNING indicates a hazardous situation which, if not avoided, could result in death or serious injury.

CAUTION indicates a hazardous situation which, if not avoided, could result in minor or moderate injury.

NOTICE Indicates a message not related to personal injury.

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2 Introduction
2.1 Overview
2.1.1 Purpose and scope
This document details the host interface specifications for the cobas® 6500 analyzer series for SW 2.2.0.
This interface regulates data transmissions between the cobas® 6500 analyzer series and the hospital and
laboratory information system.

Therefore, this manual gives programmers a description of the basic operational features of the cobas®
6500 analyzer series, in order to enable them to connect to a host system, such as Laboratory Information
Systems, Hospital Information Systems or Work Area Manager.

The main part of this document consists of a series of tables that show the information needed to
successfully interface to the system. The basic concept of data transfer in this interface is the exchange of
data and control frames between the host system and the analyzer.

2.1.2 Audience
This manual is written for:
 Developers of Hospital Information Systems / Laboratory Information Systems (HIS/LIS), who need to
create programs that connect to the cobas® 6500 analyzer series.
 Authorized Roche Diagnostics personnel who need to configure or troubleshoot the host
communications of the cobas® 6500 analyzer series. Depending on the type of host system and on the
work flow in the laboratory the cobas 6500 host interface offers a set of configurable features.

2.2 System overview

2.2.1 cobas u 601 urine analyzer
The cobas u 601 urine analyzer is a semi-automatic urinalysis system intended for in vitro qualitative or semi-
quantitative determination of urine analytes, including specific gravity (SG), pH, leukocytes, nitrite, protein,
glucose, ketones, urobilinogen, bilirubin, erythrocytes, and color.

2.2.2 cobas u 701 microscopy analyzer

The cobas u 701 microscopy analyzer is intended for in vitro qualitative or semi-quantitative determination
of urine analytes, including pathological casts, crystals, yeasts, mucus, sperm, bacteria, squamous
epithetical cells, non-squamous epithetical cells, hyaline casts, erythrocytes, and leukocytes.

2.2.3 Topology

u601 standalone u701 standalone

LIS LIS

TCP/IP TCP/IP

cobas u 601 cobas u 701

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c6500 (u601 and u701 connected)

LIS

TCP/IP

cobas u 601 cobas u 701

NOTICE u601 and u701 host communication is done by the TCP/IP connection from the u701.

2.2.4 LIS communication

The LIS and analyzer can communicate by
 ASTM over TCP/IP network connection

The following host protocols are supported.

For detailed protocol information, see version information in the appropriate chapters.
 cobas 6500 protocol (v8)
 cobas 6500_09 protocol (v9)

To connect the analyzer with the host system, use a commercial LAN cable with RJ45 connectors on both
sides.

NOTICE Personal computers and all information technology equipment that you connect to the device to must
meet the EN 60950, UL 60950/CSA C22.2 No. 60950 requirements for data processing equipment.

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3 Sample processing
3.1 Identifying samples on the instrument
3.1.1 Barcode and sample ID’s
By default, the analyzer reads the barcodes on the sample tubes, and uses the number on the barcode as a
sample ID. The sample ID uniquely identifies the sample in the databases and uniquely identifies the sample
in messages to and from the host.

3.1.2 Samples missing a barcode

If a sample tube’s barcode is missing or unreadable, the software generates a unique sample ID and there is
no interaction with the host before the corrective action is done.

NOTICE Sample results with generated sample ID’s are not transferred automatically to the host. The
operator has to change the unique sample ID to the sample barcode before it can be sent to the host.

Example of generated unique sample ID: 2345120150410112133

 2345:Rack ID
 1: Tube position
 20150410: YYYYMMDD
 112133: hhmmss

3.1.3 Controls missing a barcode

If a QC tube does not have a barcode, the software also generates a unique QC ID.

NOTICE QC results with generated QC ID are transferred automatically to the host.

Example of generated unique QC ID: Q001120150410104447

 Q001:Rack ID
 1: Tube position
 20150410: YYYYMMDD
 104447: hhmmss

3.1.4 Sequence numbers

If it is not possible to use barcodes, the analyzer can give each sample a number. This number increases by
1 for each sample. The host must then know the sequence of samples, and respond with the test orders.

3.2 Querying orders to the host

Test selection inquiry sent from the analyzer to the host:
Q|1|^0203^500432^3
Test selection information sent from the host to the analyzer:
O|1|0203|500432^3^operator^SAMPLE|CM|R||||||N|||20120508115956|||||||||||Q

NOTICE If the host does not answer within the defined timeout period, the analyzer will start the order and
process the sample with the default test profile defined on the analyzer.

If you want to use a unidirectional communication (sending only result to the host), then set the Timeout
in the Host configuration to 1 second.

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3.3 Returning results to the host

3.3.1 Result and Raw data transmission u601
Enable raw data transmission of results on Administration > System Configuration > Host Configuration

Data flow

cobas u 601 ASTM LIS

Send results and raw data Driver

Order of action:
Analyzer sends results and raw data

Results and Raw data

Result Record (v8):
R|1|1^ERY|2+^25 /ul^25 /ul^^||International|||F||operator|||u601
Final result in ‘arbitrary units‘ and ‘conventional units’ and ‘SI units

Result Record (v9):

R|1|1^ERY|25|/ul|International|||F||operator|||u601
Final result in ‘arbitrary units‘ or ‘conventional units’ or ‘SI units

Raw Result Record (v8 and v9):

M|1|RR|u601|1^ERY|REM_ERY_560|26.0500|26.0500
Reflectance

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3.3.2 Result and Raw data transmission u701 and c6500

Enable raw data transmission of results on Administration > System Configuration > Host Configuration

Subclasses must be defined first in the particle configuration by the operator before they can be used.

Data flow

cobas 6500 ASTM LIS

cobas u 701
2. Send results, raw data, image Driver
path

3. Read images

1. Send images

Mapped
network drive
External
storage
device

Order of action:
1. Analyzer sends images
2. Analyzer sends results, raw data, image path
3. LIS reads images

NOTICE Be aware that sending images from the analyzer to the external storage device takes some time.
Therefore the LIS needs to wait for the image path record before it can read the images from the external
storage device.

Results and Raw data without subclasses

CAUTION For all other tests than RBC and WBC, the final result is not the same as the concentration.

Result Record (v8):

R|1|1^RBC|^60.60 /HPF^266.64 /uL^60.60 /HPF^266.64 /uL||International|||F||operator|||u701
Final result in ‘arbitrary units‘ and ‘parts per high power field’ [HPF] and ‘parts per microliter’ [uL]
Concentration

Result Record (v9):

R|1|1^RBC|266.64|/uL|International|||F||operator|||u701
Final result in ‘arbitrary units‘ or ‘parts per high power field’ [HPF] or ‘parts per microliter’ [uL]

Raw Result Record (v8 and v9):

M|1|RR|u701|1^RBC|10^20^12^12^12^25^25^25^25^25^25^25^25^25^12|606|40.40|266.64|60.60
Concentration

NOTICE Only for RBC and WBC the Result Record field 4 [R Record] (data or measurement value) is equal
to Raw Result Record [RR for u 701] field 9 (/ul value) or field 10 (/HPF value).

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Results and Raw data with subclasses

CAUTION For all other tests than RBC and WBC, the final result is not the same as the concentration.

Result Record (v8):

R|1|1^RBC|^60.60 /HPF^266.64 /uL^60.60 /HPF^266.64 /uL||International|||F||operator|||u701
Final result in ‘parts per high power field’ [HPF] and ‘parts per microliter’ [uL]
Concentration

Raw Result Record (v8):

M|1|RR|u701|1^RBC|5^10^10^10^10^20^20^20^20^20^20^20^20^20^2|454|30.27|199.76|45.40
M|2|RR|u701|1-1^dysm. EC|5^10^2^2^2^5^5^5^5^5^5^5^5^5^10|152|10.13|66.88|15.20
Concentration

CAUTION With host protocol version 8 the test code RBC within the Raw Result Record means in real
RBC_X (Rest of the main class). The main class (summary of all subclasses) is only submitted with host
protocol version 9.

Result Record (v9):

R|1|1^RBC|266.64|/uL|International|||F||operator|||u701
R|2|1-0^RBC_X|199.76|/uL|International|||F||operator|||u701
R|3|1-1^dysm. EC|66.88|/uL|International|||F||operator|||u701
Final result in ‘parts per high power field’ [HPF] or ‘parts per microliter’ [uL]

Raw Result Record (v9):

M|1|RR|u701|1^RBC|10^20^12^12^12^25^25^25^25^25^25^25^25^25^12|606|40.40|266.64|60.60
M|2|RR|u701|1-0^RBC_X|5^10^10^10^10^20^20^20^20^20^20^20^20^20^2|454|30.27|199.76|45.40
M|3|RR|u701|1-1^dysm. EC|5^10^2^2^2^5^5^5^5^5^5^5^5^5^10|152|10.13|66.88|15.20
Concentration

NOTICE If there are subclasses defined the following rule is applied:

- If subclasses are reclassified then they are subtracted from the main class. Therefore RBC (v8) or
RBC_X (v9) is only the rest of the main class (e.g. 266.64-66.88-0.00=199.76).
- To calculate the main class value, the rest of the main class and the subclasses have to be summed
up (e.g. 199.76+66.88+0.00=266.64).

NOTICE The concentration for subclasses of semi-quantitative or qualitative parameters is only provided in
the Raw Result Record of cobas u 701.

CAUTION If the LIS implements range table borders, they must be the same as on the instrument. Please be
aware of the fact that the range table borders can be edited on cobas u 701 by a user with supervisor rights.

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3.4 Particle configuration

Define subclasses on Administration > System Settings > Measurement settings > u 701 > Particle
configuration.

The software automatically creates a default subclass _X (Rest of the main class).
Example: CRY = CRY_X + CaOxm

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3.5 Image transmission u701 and c6500

3.5.1 Microscope images
Images can be transferred with and without particle labels.
The images file names are like Image_SampleID_Index.*
 Image: Fix prefix
 SampleID: According barcode
 Index: 01-16; but only 15 images per sample are transferred as maximum.
 *Extension: *.gif or *.png

Images without particle labels are in *.gif format and have an average size of 700 kB.
Dimension: 1280 x 960 pixels

Example: Image_1111_16.gif

Images with particle labels are in *.png format and have an average size of 1000 kB.
Dimension: 1280 x 960 pixels

Example: Image_1111_16.png

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3.5.2 Map network drive

Mapping a network drive is needed for configuration of the User-SW.
The network drive is used as location, where the images will be transferred by the User-SW.
To map network drives, the Service SW must be used.
Folders with authentication can be used.

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3.5.3 Image transfer configuration

 The User-SW transfers the images to the mapped network drive which must be selected on “Image path”
(see 1).
 The images are transferred when the “Image condition” is fulfilled (see 2).
Either “No images”, only “Pathological images” or always “All images” are transferred.
“Pathological images” are samples with the abnormal data alarm (A-flag). It does not matter which test
parameter has the data alarm.
 The “Image copy mode” is either “Without labels” (*.gif files) or “With labels” (*.png files) or “Both” (see
3).
 The images are transferred to a folder for each sample. The folder naming depends on the chosen
“Analyzer” report creation and the Regional settings.
The “Analyzer” report creation is either “c 6500” or “u 701” (see 4).
The Regional settings influence the time format.

The folder names are like Analyzer_ResultReport_SampleID_DateTime.

 Analyzer: According analyzer report creation
 ResultReport: Fix prefix
 SampleID: According barcode
 DateTime: According Regional settings

Examples:
u_701_ResultReport_5_11-24-201435048PM
cobas_6500_ResultReport_5_11-24-201435048PM
cobas_6500_ResultReport_1111_25-11-2014154336

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NOTICE In case of rerun the same sample ID, the date & time from the folder will be different but not the
image file names.
If the sample ID contains special characters, they will be exchanged by “_”.

3.6 Passing results automatically to the host

In this mode, the analyzer automatically validates sample results, and then passes them immediately to the
host, including any data alarm. Otherwise, the analyzer waits for an operator to release the results before
passing them up to the host.

NOTICE There are some exceptions where automatic validation is not done. See Operator’s manual.

The validation condition triggers the transfer of results, raw data and images:
 Automatic validation all: If the result is technically ok (no error appeared) it will automatically set to
validated and sent to the host.
 Automatic validation rules: If one of the checked data alarms (flags) is set, the user has to validate the
result manually which contain this data alarm. All other result are handled like in “Automatic validation
all”
 Manual validation: All results must be validated by the user.

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3.7 Communication types

This section discusses the different types of communications between the host and the analyzer.

3.7.1 Communication and message types

Each record is introduced by field (number one) identifying the record type, and terminated by a carriage
return. The following record types are defined.

Supported records:
Record Type ID Record Name Description
H Header Record First record in every message.
Patient demographics can be sent from the
P Patient Information Record host and will be sent back.
O Test Order Record Defines the attributes of a particular order.
R Result Record Contains measurement results.
Transmission of data alarms and result
C Comment Record comment.
Transmission of raw data, additional
M Manufacturer Information Record information for sample and control results.
Q Request Information Record Test selection inquiry.
L Message Terminator Record Last record in every message.

3.7.2 Communication scenarios

This section describes the types of communication scenarios that occur between the host and the analyzer.

The host sends a Test Selection Information in response to an analyzer Test Selection Inquiry.

Test Selection Inquiry

LIS Test Selection Information Analyzer

The host can send a Test Results or QC Results independent of other communication.

Test Result Data / QC Result Data

LIS Analyzer

3.7.3 Details of message types

Sending test selections
The query sent to the host contains always Sample ID, Rack ID and the Tube position on the rack.

Sending test results

For results to be sent to the host, they must first pass validation. Validation can be done manually or
automatically. The manual validation is done by the user on the analyzer. Automatic validation is done if a
result is technically ok.

Sending QC results
The measured quality control results are sent automatically from the analyzer to the host.

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4 Interface description
4.1 Host communication settings
4.1.1 Communication setup
The host status on the analyzer is disabled by default. To establish the host communication, the host status
must be set to enable. To configure the host settings and to enable the host communication, proceed the
following procedure.
➢ To set user software’s host connection settings.
a) Choose Administration > System configuration > Host Communication.
b) Choose Edit.
c) Select the Enable host connection check box.
d) Select the Enable raw data transmission check box, if required.
e) Enter the host’s IP address and the Port 6500.
f) Select the host protocol version.
g) Choose Save.

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4.1.2 Host communication check

In case of host communication problems as sending data from the analyzer to the host system (LIS) check
host settings on the analyzer and the LIS, as well as the connection. The communication can be tested using
a host simulator on the Roche service representative’s notebook.
Before changing any settings or disconnecting the LAN cable from the analyzer, follow the procedures below.
➢ To connect the analyzer with the notebook
a) Disconnect the wireless connection on the notebook.
E.g. choose Start > Control Panel > Network and Sharing Center.
b) Disable the firewall on the notebook.
E.g. on the right side of the notebook’s taskbar click Show hidden icons.
Right-click on Symantec Endpoint Protection > disable Symantec Endpoint Protection.
c) Connect the analyzer with the notebook, using the analyzer’s connector labeled with LAN and a LAN cable.
NOTICE LAN connectors are located at the rear of the analyzer.

➢ To set notebook’s network connection settings

a) Choose Start > Control Panel > Network and Sharing Center.
b) Choose LAN-Verbindung, the LAN-Verbindung Status dialog box opens.
c) Choose Properties, the LAN-Verbindung Properties dialog box opens.
d) Choose Internet Protocol Version 4 (TCP/IPv4).
e) Choose Properties, the Internet Protocol Version 4 (TCP/IPv4) Properties dialog box opens.
f) Choose the Alternate Configuration tab.
g) Select the User configured option.
h) Under IP address enter 162.132.241.123.

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i) Under Subnet mask enter 255.255.255.0.

j) Under Default Gateway enter 162.132.241.1.
k) Choose OK, the Internet Protocol Version 4 (TCP/IPv4) Properties dialog box closes.
l) Choose Close, the LAN-Verbindung Properties dialog box closes.
m) Choose Close, the LAN-Verbindung Status dialog box closes.
n) Close the Network and Sharing Center window.

NOTICE The following procedure must be executed if advised by Roche Global Customer Support
only. It may misadjust the analyzer’s network settings and operating system if the FSE is not experienced.

➢ To set analyzer’s network connection settings.

a) Choose Start > Settings > Control Panel > Network Connections.
b) Double-click the Local Area Connection icon, the Local Area Connection Status dialog box opens.
c) Choose Properties, the Local Area Connection Properties dialog box opens.
d) Choose Internet Protocol (TCP/IP).
e) Choose Properties, the Internet Protocol (TCP/IP) Properties dialog box opens.
f) Select Alternate Configuration.
g) Select the Use the following IP address option.
h) Under IP address, enter 162.132.241.115.
i) Under Subnet mask, enter 255.255.255.0.
j) Under Default Gateway enter 162.132.241.1.
k) Choose OK, the Internet Protocol (TCP/IP) Properties dialog box closes.
l) Choose OK, the Local Area Connection Properties dialog box closes.
m) Choose OK, the Local Area Connection Status dialog box closes.
n) Close the Network Connections window.

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For configuring the ASTM Host Simulator use the following procedure.
➢ To set ASTM Host Simulator’s connection settings
a) From the Options menu, choose Common Settings.
b) Choose the Device/Trace tab.
c) From the Instrument drop/down list, choose cobas 6500.
d) Choose OK, the Common Settings dialog box closes.
e) From the Options menu, choose Interface Settings.
f) Choose the Network Settings tab.
g) Under Local Device is ..., select the TCP/IP Server option.
h) Under Server Settings > Local IP address, enter 162.132.241.123.
i) Under Server Settings > Local Port No, enter 6500.
j) Choose OK, the Interface Settings dialog box closes.
NOTICE A successful connection with the analyzer is indicated with a green bar and the message “Winsock
Status: Connected” underneath the instrument connection icon. Otherwise check the analyzer’s network
connection settings, see procedure at the end of this chapter.

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➢ To set user software’s host connection settings on the analyzer.

a) Choose Administration > System Configuration > Host Configuration.
b) Choose Edit.
c) Select the Enable host connection check box.
d) Select the Enable raw data transmission check box, if necessary.
e) Under IP address, enter 162.132.241.123.
f) Under Port, enter 6500.
g) Under Host protocol version, choose c 6500.
h) Choose Save.
i) Restart the analyzer.
NOTICE Analyzer has to be connected with the Notebook.

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➢ To transmit data from the analyzer to the notebook

a) Choose Routine > Manage test results.
b) Select the check boxes of the results to be transmitted.
c) Choose Send.
NOTICE For receiving the results on the notebook, the appropriate host simulator must be started and
configured according to the procedure above.

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4.2 Physical layer specifications

4.2.1 Electrical Characteristics
The voltage and impedance levels for the sender and receiver circuits are as specified in the IEEE 802.3
standard.15.

Signal Levels
The signal levels conform to the IEEE 802.3 standard.15.

Character Structure
 The method of data transmission is TCP/IP. The order of the bits in a character is:
(1) One start bit, corresponding to a binary 0;
(2) The data bits of the character, least significant bit transmitted first;
(3) Parity bit; and
(4) Stop bit(s), corresponding to a binary 1.
 The time between the stop bit of one character and the start bit of the next character may be of any
duration. The data interchange circuit is in the marking condition between characters.
 Even parity corresponds to a parity bit chosen in such a way that there are an even number of 1 bit in the
sequence of data bits and parity bit. Odd parity corresponds to an odd number of 1 bit when formed in
the same way.
 All devices must be capable of sending and receiving characters consisting of one start bit, eight data
bits, no parity bit, and one stop bit.
 The default character structure consists of one start bit, eight data bits, no parity bit, and one stop bit.
Eight-data-bit character sets are allowed but not specified by this standard. Other character structures

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can be used for specialized applications, for example, seven data bits, odd, even, mark or space parity,
or two stop bits.
 The character bit sequencing, structure, and parity sense definitions conform to ANSI standards X3.15-
1976 and X3.16-1976.12,13

Speed
The data transmission rate for instruments shall conform to IEEE 802.315 and operate at least
10MBit/second. A host system using TCP/IP must have the capability to conform to a minimum speed of 10
MBit/second.

Interface Connections
The conforming connection utilizes an eight-line connector (RJ45). The connector contact assignments
conform to the ANSI EIA/TIA 568B standard16 (also called the AT&T specification) and are as follow:

Connector contact assignments:

No Color
1 white / orange
2 orange
3 white / green
4 blue
5 white / blue
6 green
7 white / brown
8 brown

4.2.2 Mechanical Characteristics

Connector
The conforming connector associated with the instrument and computer is a commercial type RJ-45F style
connector. The connector dimensions must correspond to those given in the ANSI EIA/TIA 568B standard16.

Cable
Category 5 cables as defined by ANSI EIA/TIA 568B16 are preferred for all connections. In general, no
extension cables should be required to connect the instrument to the computer network. Detailed
requirements of an interconnecting cable are undefined, but good engineering practice should be followed in
selecting the cable and connectors. Low-capacitance cable and shielded connectors may be necessary to
suppress electromagnetic interface (EMI). Appropriate connector-locking hardware should be used at the
conforming connectors.

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5 ASTM Reference
5.1 ASTM protocol (LIS2 – A2)
5.1.1 Background
The standards for communication between automatic analyzers and host computers are LIS1-A (Standard
Specification for Low-Level Protocol to Transfer Messages between Clinical Laboratory Instruments and
Computer Systems) and LIS2-A2 (Standard Specifications for Transferring Information Between Clinical
Instruments and Computer Systems).

5.1.2 Communication Processing Layers

Application Layer

ASTM Upper Layer LIS2-2A

ASTM Lower Layer LIS1-A

Physical Layer

Details of the ASTM protocol can be found in

 LIS1-A (ASTM E1381-02) Low Level Protocol
(NCCLS. Standard Specification for Low-Level Protocol to Transfer Messages Between Clinical
Laboratory Instruments and Computer Systems. NCCLS document LIS1-A [ISBN 1-56238-489-9].
NCCLS, 940 West Valley Road, Suite 1400, Wayne, Pennsylvania 19087-1898 USA, 2003.)
 LIS2-A2 (ASTM E1394-97) High Level Protocol
(NCCLS. Specification for Transferring Information Between Clinical Laboratory Instruments and
Information Systems; Approved Standard—Second Edition. NCCLS document LIS2-A2 [ISBN 1-56238-
550-X]. NCCLS, 940 West Valley Road, Suite 1400, Wayne, Pennsylvania 19087-1898 USA, 2004.)

5.1.3 ASTM Lower Layer

ASTM lower layer receives messages for a transmission request from the upper layer. These messages are
then split into frames and sent to a communication medium to be transmitted to other parties. ASTM lower
layer also constructs frames received from a communication medium to recreate messages to be transferred
to the ASTM upper layer as reception messages.

5.1.4 ASTM syntax

The structure of the sentences to be transferred, according to ASTM Communication Regulation, is
explained in this section. Between the analyzer and the host, various data such as Test Results are
transferred back and forth. All of these data conform to this syntax.

Definitions
Message:
A message is constructed with an arrangement of several records (refer to the next item). It is the smallest
unit of information transferred between a host and an analyzer. Messages begin with a ‘Message Header
Record’ that indicates the beginning of a message and end with a ‘Message Termination Record’ that
indicates the end of a message.

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Record:
A record is constructed from several fields and expresses a single purpose (such as to specify test result
data). A record may be repeated or used singularly in a message. Code that indicates the purpose of a
record is noted in the first character of that record.

Field:
A field is the ASTM’s smallest element to construct information. Attributes for a field (name, format, and
meanings) are defined in units in a record.

Messages
Each message has a number of records. A message is a group of records that begins with a Header Record
and ends with a Message Terminator Record. Each record has a number of fields. Each field is by default
separated by the vertical bar | character (the actual definition of which character is used for field separation is
done with the Header Record).
Following is a description of the records and the fields within each record:

Record Type ID Record Name

H Message Header Record
P Patient Information Record
O Test Order Record
R Result Record
C Comment Record
M Manufacturer Information Record
L Message Termination Record
Q Request Information Record

Delimiters
For the purpose of providing examples, the following delimiters are used:

 Field delimiter = vertical bar (|) Latin-1(124)

 Repeat delimiter = backslash (\) Latin-1(96)
 Component delimiter = caret (^) Latin-1(94)
 Escape delimiter = ampersand (&) Latin-1(38)

Record Delimiter:
Carriage return (13) shall be the delimiter for the end of any of the defined record types.

Field Delimiter:
A single allowable character, excluding Latin-1(13) (carriage return), shall separate adjacent fields. The field
delimiter is variable and defined in the message header. The same delimiter must be used in all records
following a header and preceding a message terminator record.

Repeat Delimiter:
A repeat delimiter is a single allowable character, excluding Latin-1(13) and the value for the field delimiter.
The repeat delimiter must be defined in the message header and is used to separate variable numbers of
descriptors for fields containing parts of equal members of the same set.

Component Delimiter:
A component delimiter is a single allowable character, excluding Latin-1(13) and the field and repeat
delimiter values. The component delimiter is used to separate data elements of fields of a hierarchical or
qualifier nature. For example, the street, city, state, zip, etc. of an address field would be separated by
component delimiters.

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Escape Delimiter:
An escape delimiter is a single allowable character, excluding Latin-1(13) and the field, repeat, and
component delimiter values. The escape delimiter is used within text fields to signify special case operations.
Applications of the escape delimiter are optional and may be used or ignored at the discretion of either the
transmitter or the receiver. However, all applications are required to accept the escape delimiter and use it to
correctly parse fields within the record.

Message Transmission Phases

To establish which system sends and which system receives information and to assure the actions of sender
and receiver are well coordinated, there are three distinct phases in transferring information:
 Establishment Phase
 Transfer Phase
 Termination Phase

Within the transfer phase, all records of the corresponding message are grouped into longer frames to
increase speed. The records are separated through a [CR] character. Therefore, to obtain pure ASTM
records again, the receiver must concatenate all the frames and wait for a [EOT] character. Then, finally, he
can process the frame and split it into different records using the [CR] as separator.

5.2 ASTM text content (LIS2 – A2)

5.2.1 Record levels
The following table shows the Standard Record types and levels specified by the protocol LIS2-A2.

Level Record Name Record Type ID

0 Message Header Record H
1 Patient Information Record P
2 Test Order Record O
3 Result Record R
1…3 Comment Record C
 Data alarms for a test parameter (C-I)
 Comment for a result (C-G)
1…3 Manufacturer Information Record M
 Raw Result Record (M-RR)
 Result Context Record (M-RC)
 Image Path Record (M-IR)
0 Message Termination Record L
1 Request Information Record Q

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5.2.2 Messages used in host communication

The following section shows detailed descriptions of each of message sent between the host and analyzer,
and the ASTM records used in each.

Message Communication direction

Test Selection Information Host to analyzer
Test Selection Inquiry Analyzer to host
Test Result Data Analyzer to host
QC Result Data Analyzer to host

Messages transmitted by the analyzer

Messages transmitted from the analyzer to the host are shown in the table below.
In the following charts:
 [ ] Square brackets indicate an optional segment. (0 - 1 times)
 { } Curly brackets indicate a segment or group of segments that may be repeated. (1 - n times.)

Message Records Reason

Test Selection Inquiry H Inquiry is made for the
Q requested sample just after a
L rack has passed the barcode
reader.
Test Result Data u601 H Upload of the Test results or
QC Result Data u601 [P] QC results at the point when
O the results for the sample have
{ been calculated.
R
[C-I]
}
{
[M-RR]
}
M-RC
[C-G]
L
Test Result Data u701 H Upload of the Test results or
QC Result Data u701 [P] QC results at the point when
O the results for the sample have
{ been evaluated.
R
[C-I]
}
{
[M-RR]
}
M-RC
[M-IR]
[C-G]
L

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Messages transmitted by the host

The analyzer can receive the following message from a connected LIS.

Message Records Reason

Test Selection Information H Test selection download for a sample as
[P] an answer to a test selection inquiry.
O
L

5.2.3 Record description

Each record of the ASTM message is divided into fields and subfields.

Field attributes
Types of attributes held by a field are explained below.
Attribute Description

Field The number of the field in the record.

Reference The paragraph in the ASTM definitions that describes the field. See
NCCLS. Specification for Transferring Information Between Clinical
Laboratory Instruments and Information Systems: Approved
Standard, Second Edition. NCCLS document LIS2-A2 [ISBN 1-
56238-550-X]. NCCLS, 940 West Valley Road, Suite 1400, Wayne,
Pennsylvania 19087-1898 USA, 2004.
Value This shows either:
 The precise text to be sent.
 The format of the field.

The format of the field can take one of the following values:
 Character: A single character.
 String: A character string.
 Number: A numeric value. Positive (+) or negative (-) is
indicated before the numeric value. If it is not indicated, it is
treated as positive (+).
 Date: Always use the 4-digit Gregorian year. The format is
YYYYMMDD (YYYY is the 4-digit Gregorian year, MM is the
month, DD is the day). For example, September 5, 2009 is
indicated 20090905.
 Time: Military time. (24 hour)
The format is HHMMSS (HH is the hour, MM is the minute, and SS
is the second).
 DateTime: A combination of Date and Time.
The format is: YYYYMMDDHHMMSS.
 Complex: A field in which multiple data components are
combined, separated by a component delimiter. Each
component may take one of the other formats.

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Host If sent from the host or LIS, this field is either:

 R, required
 O, optional
Analyzer If sent from analyzer, this field is either:
 R, required (in other words, always sent)
 O, optional
Description A description of the field, including use and permitted values. In the
case of complex fields, this includes a description of individual
components.
Version The following host protocols are supported.
 cobas 6500 protocol
 cobas 6500_09 protocol
Content of cobas 6500 protocol will be marked as “8”.
Content of cobas 6500_09 protocol will be marked as “9”

Text encodings
All data shall be represented as eight-bit, single-byte, coded graphic character values as defined in ISO
8859-1:1987.1 The eight-bit values, within the range from 0 to 127 of ISO 8859-1:19871 correspond to the
ASCII standard character set. Values from 0 to 31 are disallowed with the exception of 7 (BEL), 9 (Horizontal
tab), 11 (Vertical tab), and 13 (CR), where 13 is reserved as a record terminator. Values from 32 to 126 and
from 128 to 254 are allowed. Values 127 and 255 are also not allowed. It is the responsibility of the
instrument vendor and information system vendor to understand the representation of any extended or
alternate character set being used. As an example, the numeric value 13.5 would be sent as four-byte value
characters 13.5 or Latin-1(49), Latin-1(51), Latin-1(46), and Latin-1(53).

Allowed Characters: 7, 9, 11, 12, 13, 32 to 126, 128 to 254

Disallowed Characters: 0 to 6, 8, 10, 14 to 31, 127, 255

Within text data fields, only the Latin-1 characters 32 to 126 and the undefined characters 128 to 254 are
permitted as usable characters (excluding those used as delimiter characters in a particular transmission).
Furthermore, all characters used as delimiters in a particular transmission are excluded from the permitted
range. The sender is responsible for screening all text data fields to ensure that the text does not contain
those delimiters. Unless otherwise stated, contents of data fields shall be case sensitive.

5.2.4 Message Header Record

This record contains information about the sender and other important general information.

u601 standalone:
H|\^&|||AN_01^u601^2.2.0^9^UW602000001^|||||||P|LIS2-A2|20100603155801

u701 standalone:
H|\^&|||AN_02^u701^2.2.0^9^^UW702000002|||||||P|LIS2-A2|20100603155801

c6500 (u601 and u701 connected):

H|\^&|||AN_0102^Cobas6500^2.2.0^9^UW602000001^UW702000002|||||||P|LIS2-A2|20100603155801

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Field Ref. Value Host An. Description Ver.

1 6.1 H R R Record Type ID 8, 9

2 6.2 |\^& R R Delimiter Definition 8, 9

Delimiter definitions. Fixed values:

 | Field delimiter = vertical bar [ascii 124]
 \ Repeat Delimiter = backslash [ascii 92]
 ^ Component Delimiter = caret [ascii 94]
 & Escape character = ampersand [ascii 38]

3 6.3 Not used 8, 9

4 6.4 Not used 8, 9
5 6.5 Complex - R Sender Name or ID 8, 9
Analyzer name
^System configuration
^User software version
^Protocol version
^Serial number u601
^Serial number u701
 System configuration is either in u601 standalone mode,
u701 standalone mode or c6500 connected mode (both
analyzer connected to a system).
 User software version is the software version on the
analyzer.
 Protocol version is the host protocol used which is either 8 or
9.
 Serial number (depending on configuration).

O - No need to send this information from the host to the analyzer. 8, 9

6…11 6.6 – Not used 8, 9
6.11

12 6.12 P O R Processing ID 8, 9
Fixed value P, meaning production.

13 6.13 LIS2-A2 O R Version No. 8, 9

Fixed string LIS2-A2

14 6.14 DateTime R R Date and Time of Message 8, 9

5.2.5 Patient Information Record

This record is used to transfer patient demographic data.

Empty patient data sent from the host to the analyzer (v8):
P|1

Empty patient data sent from the analyzer to the host (v8):
P|1

NOTICE Patients can be created manually but they will not be sent back to the host.
Only patients sent from the host to the analyzer will be sent back from the analyzer to the host.

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Patient data sent from the host to the analyzer (v9):

P|1|13A930|302683||Doe^John||1891201|M|||||B1

Patient data sent from the analyzer to the host (v9):

P|1|13A930|302683||Doe^John||1891201|M|||||B1

NOTICE If no patient data is connected to the sample result then no patient record is sent back to the host

Field Ref. Value Host An. Description Ver.

1 7.1 P R R Record Type ID 8, 9

2 7.2 1 R R Sequence Number 8, 9
Fixed value 1.

3 7.3 String O O Patience-Assigned Patient ID 9

Max length of 50 characters.

4 7.4 String R R Laboratory-Assigned Patient ID 9

Max length of 50 characters.

If the host did not sent an ID then the analyzer cannot sent it back.
It cannot be defined in the User SW.

5 7.5 Not used 9

6 7.6 Complex O O Patient Name 9
Last Name^First Name
 Each component has a max length of 22 characters.

7 7.7 Not used 9

8 7.8 Date O O Birthdate 9
9 7.9 Character O O Patient Sex 9
 M Male
 F Female
 U Unknown
 Any other value defaults to unknown, and is returned to the host
as U.

10...13 7.10 – Not used 9

7.13
14 7.14 String O O Attending Physician ID 9
Either name or code.
Max length of 50 characters.

15…35 7.15 – Not used 9

7.35

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5.2.6 Test Order Record

This record holds information regarding the analysis request and sample information. It is sent to the
analyzer within test selection message, and to the host within result message.

Order record sent from the host to the analyzer:

O|1|00321068|05^3^^|CM|R||||||N|||20000202035009|||||||||||Q

Order record sent from the host to the analyzer with unknown request:
O|1|00321068|713450^3^^|||||||||||20000202035009|||||||||||Y

Order record sent from the analyzer to the host within the Test Result message:
O|1|00321068|713450^1^operator^SAMPLE|CM|R||||||N|||20120508132753|||||||||||F

Order record sent from the analyzer to the host within the Test Result message with an error:
O|1|00321068|713450^3^operator^SAMPLE|CM|R||||||N|||20000202035009|||||||||||X

NOTICE If there was no result because of an error during measurement, the order will be sent back to the
host with an ‘X’ as Report type.

Order record sent from the analyzer to the host within the QC Result message:
O|1|004215/8/2012|500425^1^operator^CONTROL|C|R||||||Q|||20120508131539|||||||||||F

Field Ref. Value Host An. Description Ver.

1 8.4.1 O R R Record Type ID 8, 9

2 8.4.2 Number R R Sequence Number 8, 9
3 8.4.3 String R R Specimen ID 8, 9
Either barcode or sequence number.

4 8.4.4 Complex R/Q R Instrument Specimen ID 8, 9

Rack ID
^Position No
^Operator ID
^Data Carrier Type

5 8.4.5 String R R Universal Test ID 8, 9

 C u601
 P u601 reduced
 M u701
 S u601 sieve to u701
 CM u601 & u701
 PM u601 reduced & u701

6 8.4.6 R O R Priority 8, 9
Fixed value R, meaning routine.

7…11 8.4.7 – Not used 8, 9

8.4.11
12 8.4.12 Character - R Action Code 8, 9
 N New order
 Q Quality control

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R - Action Code 8, 9
 N New order
 C Cancel order

13…14 8.4.13 – Not used 8, 9

8.4.14
15 8.4.15 DateTime R R Date/Time Specimen Received 8, 9
16…25 8.4.16 – Not used 8, 9
8.4.25
26 8.4.26 Character - R Report Types 8, 9
 F Final result
 X Order cannot be done

R - Report Types 8, 9
 Q Query response
 Y Order not present

5.2.7 Result Record

The analyzer uses the result record to upload the details of test results and QC result.

Result Record (u601)

A semi-quantitative test result (v8):
R|1|1^ERY|2+^25 /ul^25 /ul^^||International|||F||operator|||u601

A semi-quantitative test result (v9):

R|1|1^ERY|25|/ul|International|||F||operator|||u601

A semi-quantitative QC result (v8):

R|1|1^ERY|neg^neg^neg^^||International|||F||operator|||u601

A semi-quantitative QC result (v9):

R|1|1^ERY|neg||/ul|International|||F||operator|||u601

A result for SG without N data alarm (v8):

R|12|22^SG|1.000^1.000^1.000^^||International|||F||operator|||u601

A result for SG without N data alarm (v9):

R|12|22^SG|1.000||International|||F||operator|||u601

A result for SG with N data alarm (v8):

R|12|22^SG|-^-^-^^||International|||F||operator|||u601

A result for SG with N data alarm (v9):

R|12|22^SG|-||International|||F||operator|||u601

NOTICE In case of N data alarm the SG result is reported as a dash sign (“-”) instead of any values.

Result Record without subclasses (u701)

A quantitative test result (v8):
R|1|1^RBC|^60.60 /HPF^266.64 /uL^60.60 /HPF^266.64 /uL||International|||F||operator|||u701

A quantitative test result (v9):

R|1|1^RBC|266.64|/uL|International|||F||operator|||u701
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Result Record with subclasses (u701)

A quantitative test result (v8):
R|1|1^RBC|^60.60 /HPF^266.64 /uL^60.60 /HPF^266.64 /uL||International|||F||operator|||u701

NOTICE With host protocol version 8 it is not possible to send results of subclasses. Subclass results are
only submitted with host protocol version 9.

A quantitative test result (v9):

R|1|1^RBC|266.64|/uL|International|||F||operator|||u701
R|2|1-0^RBC_X|199.76|/uL|International|||F||operator|||u701
R|3|1-1^dysm. EC|66.88|/uL|International|||F||operator|||u701

Field Ref. Value Host An. Description Ver.

1 9.1 R R Record Type ID 8, 9

2 9.2 Number R Sequence Number 8, 9
3 9.3 Complex R Universal Test ID 8, 9
Test No^Test code

4 9.4 Complex R Data or Measurement Value 8

u601 results including units:
Arbitrary Result
^Conventional Result
^SI Result
^empty
^empty

R Data or Measurement Value 8

u701 results including units:
Arbitrary Result
^p/HPF Result
^p/µl Result
^p/HPF Concentration
^p/µl Concentration

String R Data or Measurement Value 9

u601 or u701 result according chosen measurement unit without
units (Units are in field #5)
5 9.5 Not used 8
String R Units 9
6 9.6 String R Reference Ranges 8, 9
7…8 9.7 – 9.8 Not used 8, 9
9 9.9 F R Result Status 8, 9
Fixed value R, meaning final result

10 9.10 Not used 8, 9

11 9.11 String R Operator Identification 8, 9
12 9.12 Not used 8
13 9.13 Not used 8
DateTime R Date/Time Test Completed 9
14 9.14 String R Instrument Identification 8, 9
 u601
 u701

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5.2.8 Comment Record (following Result Record)

Record to transfer comments regarding the measured result. This record is transmitted by the analyzer,
either by adding a comment to a result, or by passing on data alarms to the host.

Data alarms for a test parameter:

C|1|I|A^M|I

NOTICE The Result Record is followed by a Comment Record which contains all data alarms (flags) that
belong to the test parameter.
If no data alarms are triggered, then the record is not sent.

Comment for a result:

C|1|I|Comment|G

NOTICE The result comment is for the whole result and therefore only sent with the last test parameter result
record.
If no result comment was entered, then the record is not sent.

Last test parameter result with data alarm and result comment:
R|12|22^SG|1.05||International|||F||operator|||u601
C|12|I|A|I
C|1|Comment

Field Ref. Value Host An. Description Ver.

1 10.1 C R Record Type ID 8, 9

2 10.2 Number R Sequence Number 8, 9
3 10.3 I R Comment Source 8, 9
Fixed value I, meaning clinical instrument system
4 10.4 Complex R Comment Text 8, 9
Each data alarm is separated by the delimiter ^
See appendix 6.1
String R Comment Text 9
Free result comment.
Max length of 280 characters.

5 10.5 Character R Comment Type 8, 9

 I Result data alarms (flags) from the analyzer
R Comment Type 9
 G Generic/free result comment

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5.2.9 Request Information Record

This record is used to request information for new tests or tests previously ordered.

From analyzer to the host with sample identified by barcode

Q|1|^123456^05^1

From analyzer to the host with sample identified by sequence number

Q|1|^23^05^1

NOTICE The analyzer is sending Sample ID, Rack ID and Tube position to the host.
Using barcodes, the Rack ID and Tube position is normally not send from the host to the analyzer. Using
sequence numbers, the Rack ID and Tube position must be send from the host to the analyzer.

Field Ref. Value Host An. Description Ver.

1 11.1 Q R Record Type ID 8, 9

2 11.2 1 R Sequence Number 8, 9
3 11.3 Complex R Starting Range ID Number 8, 9
empty
^Sample ID
^Rack ID
^Tube Position

5.2.10 Message Termination Record

This is used as the final record in every message, to show that the message is completed.

Completed normally:
L|1|N

Field Ref. Value Host An. Description Ver.

1 12.1 L R R Record Type ID 8, 9

2 12.2 1 R R Sequence Number 8, 9
Fixed value 1.
3 12.3 N O R Termination Code 8, 9
Fixed value N, meaning normal termination

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5.2.11 Manufacturer Information Record

Raw Result Record (u601)
This record is used to send raw data of measured u601 results.

Raw result:
M|1|RR|u601|1^ERY|REM_ERY_560|26.0500|26.0500

Raw result for test parameter SG without N-flag:

M|17|RR|u601|22^SG||1.0001|

Raw result record for SG with N-flag:

M|17|RR|u601|22^SG||-|

NOTICE In case of N-flag the SG reflectance is reported as a dash sign (“-”) instead of any values.

Field Ref. Value Host An. Description Ver.

1 14 M R Record Type ID 8, 9
2 14 Number R Sequence Number 8, 9
3 14 RR R Record Type Sub ID 8, 9
Fixed value RR, meaning raw result.

4 14 u601 R Analyzer Identification 8, 9

Fixed value u601, meaning cobas u 601.
5 14 Complex R Universal Test ID 8, 9
Test Number^Test Code
See appendix 6.2 and 6.3

6 14 String R LED frequency 8, 9

7 14 String R Reflectance in % without color compensation 8, 9

8 14 String R Reflectance in % corrected 8, 9

Raw Result Record (u701)

This record is used to send raw data of measured u701 results.

Raw result with counts of 15 images

M|1|RR|u701|1^RBC|7^9^8^12^10^7^9^8^12^10^7^9^8^12^10|138|9.20|60.72|13.8

Raw result with counts of 5 images

M|1|RR|u701|1^RBC|^0^0^0^0^0^0^^0^0^0^0^0^0^1|2|0.15|1.02|0.23

Raw result with subclasses (v8):

M|1|RR|u701|1^RBC|5^10^10^10^10^20^20^20^20^20^20^20^20^20^2|454|30.27|199.76|45.40
M|2|RR|u701|1-1^dysm. EC|5^10^2^2^2^5^5^5^5^5^5^5^5^5^10|152|10.13|66.88|15.20

CAUTION With host protocol version 8 the test code RBC means in real RBC_X (Rest of the main class).
The main class (summary of all subclasses) is only submitted with host protocol version 9.

Raw result with subclasses (v9):

M|1|RR|u701|1^RBC|10^20^12^12^12^25^25^25^25^25^25^25^25^25^12|606|40.40|266.64|60.60
M|2|RR|u701|1-0^RBC_X|5^10^10^10^10^20^20^20^20^20^20^20^20^20^2|454|30.27|199.76|45.40
M|3|RR|u701|1-1^dysm. EC|5^10^2^2^2^5^5^5^5^5^5^5^5^5^10|152|10.13|66.88|15.20

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Field Ref. Value Host An. Description Ver.

1 14 M R Record Type ID 8, 9
2 14 Number R Sequence Number 8, 9
3 14 RR R Record Type Sub ID 8, 9
Fixed value RR, meaning raw result.

4 14 u701 R Analyzer Identification 8, 9

Fixed value u701, meaning cobas u 701.
5 14 Complex R Universal Test ID 8, 9
Test Number^Test Code

6 14 Complex R Count of Images 8, 9

Count of Image 1
^Count of Image 2
^Count of Image 3
^Count of Image 4
^Count of Image 5
^Count of Image 6
^Count of Image 7
^Count of Image 8
^Count of Image 9
^Count of Image 10
^Count of Image 11
^Count of Image 12
^Count of Image 13
^Count of Image 14
^Count of Image 15
7 14 Number R Sum of Counts 8, 9
8 14 String R Sample average 8, 9
9 14 String R /µl concentration 8, 9
10 14 String R /HPF concentration 8, 9

Result Context Record (u601 normal measurement)

This record is used to send result context information which belongs to the measured u601 sample result.

Result context for a normal sample result:

M|1|RC|u601|00002|20110531|20110530|00001|20110531

Field Ref. Value Host An. Description Ver.

1 14 M R Record Type ID 8, 9
2 14 Number R Sequence Number 8, 9
3 14 RC R Record Type Sub ID 8, 9
Fixed value RC, meaning result context.
4 14 u601 R Analyzer Identification 8, 9
Fixed value u601, meaning cobas u 601.
5 14 String R Calibration Strip Lot Number 8, 9
6 14 Date R Calibration Strip Expiration Date 8, 9
7 14 Date R Calibration Execution Date 8, 9

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8 14 String R Test Strip Lot Number 8, 9

9 14 String R Test Strip Expiration Date 8, 9

Result Context Record (u701 normal measurement)

This record is used to send result context information which belongs to the measured u701 sample result.

Result context for a normal sample result:

M|1|RC|u701|00001|20110531|20110530||

Field Ref. Value Host An. Description Ver.

1 14 M R Record Type ID 8, 9
2 14 Number R Sequence Number 8, 9
3 14 RC R Record Type Sub ID 8, 9
Fixed value RC, meaning result context.

4 14 u701 R Analyzer Identification 8, 9

Fixed value u701, meaning cobas u 701.
5 14 String R Test Cuvette Lot Number 8, 9
6 14 Date R Test Cuvette Expiration Date 8, 9
7 14 Date R Microscope check Execution Date 8, 9
8 14 Not used 8, 9
9 14 Not used 8, 9

Result Context Record (u601 control measurement)

This record is used to send result context information which belongs to the measured u601 QC result.

Result context for a QC result:

M|1|RC|u601|00001|20110531|20110530|00003|20111206|CONTLOW|00002|20110607|20110530|1

Field Ref. Value Host An. Description Ver.

1 14 M R Record Type ID 8, 9
2 14 Number R Sequence Number 8, 9
3 14 RC R Record Type Sub ID 8, 9
Fixed value RC, meaning result context.
4 14 u601 R Analyzer Identification 8, 9
Fixed value u601, meaning cobas u 601.
5 14 String R Calibration Strip Lot Number 8, 9
6 14 Date R Calibration Strip Expiration Date 8, 9
7 14 Date R Calibration Execution Date 8, 9
8 14 String R Test Strip Lot Number 8, 9
9 14 String R Test Strip Expiration Date 8, 9
10 14 String R Control Name 8, 9
11 14 String R Control Lot Number 8, 9
12 14 Date R Control Expiration Date 8, 9
13 14 Date R Control Execution Date 8, 9
14 14 Number R Control Level 8, 9

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Result Context Record (u701 control measurement)

This record is used to send result context information which belongs to the measured u701 QC result.

Result context for a QC result:

M|1|RC|u701|00003|20111206|20110605|||CONTLOW|00001|20110607|20110530|1

Field Ref. Value Host An. Description Ver.

1 14 M R Record Type ID 8, 9
2 14 Number R Sequence Number 8, 9
3 14 RC R Record Type Sub ID 8, 9
Fixed value RC, meaning result context.

4 14 String R Analyzer Identification 8, 9

Fixed value u701, meaning cobas u 701.
5 14 String R Test Cuvette Lot Number 8, 9
6 14 Date R Test Cuvette Expiration Date 8, 9
7 14 Date R Microscope check Execution Date 8, 9
8 14 Not used 8, 9
9 14 Not used 8, 9
10 14 String R Control Name 8, 9
11 14 String R Control Lot Number 8, 9
12 14 Date R Control Expiration Date 8, 9
13 14 Date R Control Execution Date 8, 9
14 14 Number R Control Level 8, 9

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Image Path Record (u701)

This record is used to send the image path of u701 sediment images to the host.

The image path is divided into record fields to reduce data transmission. The image path must be set
together with record field 5, 6 and 7 at the host.

NOTICE As the backslash is defined in the header record to be a repeat delimiter, be aware that you will have to
escape the backslash character in the ASTM transmission.

Image path with both types of images (with and without label):
M|1|IR|u701|X:&R&images&R&cobas_6500_ResultReport_1111_27032015005518|Image_1111_01^Image_1111_02^I
mage_1111_03^Image_1111_04^Image_1111_05^Image_1111_06^Image_1111_07^Image_1111_08^Image_1111_09
^Image_1111_10^Image_1111_11^Image_1111_12^Image_1111_13^Image_1111_14^Image_1111_16|gif^png|

Image path with labels and copy error:

M|1|IR|u701|X:&R&images&R&cobas_6500_ResultReport_1111_27032015005518|Image_1111_01^Image_1111_02^I
mage_1111_03^Image_1111_04^Image_1111_05^Image_1111_06^Image_1111_07^Image_1111_08^Image_1111_09
^Image_1111_10^Image_1111_11^Image_1111_12^Image_1111_13^Image_1111_14^Image_1111_16|^png|E

Field Ref. Value Host An. Description Ver.

1 14 M R Record Type ID 9
2 14 Number R Sequence Number 9
3 14 IR R Record Type Sub ID 9
Fixed value IR, meaning image path record..

4 14 u701 R Analyzer Identification 9

Fixed value u701, meaning cobas u 701.
5 14 String R Image path 9
File path were images are exported.
6 14 Complex R Image names 9
Name of Image 1
^Name of Image 2
^Name of Image 3
^Name of Image 4
^Name of Image 5
^Name of Image 6
^Name of Image 7
^Name of Image 8
^Name of Image 9
^Name of Image 10
^Name of Image 11
^Name of Image 12
^Name of Image 13
^Name of Image 14
^Name of Image 15
7 14 Complex R Image extension 9
Extension for images without particle labels
^Extension for images with particle labels
 gif Image without particle labels
 png Image with particle labels
8 14 Character R Image error 9
 E If the image copy failed or no connection, not enough

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space, folder not created.

6 Appendices
6.1 Data Alarms
The result data which is transmitted to the host system must be checked for data alarms.

WARNING Data alarms are in order to bring some of the values to the attention of the operator. Therefore it
is important that these data alarms are displayed on the host system. If these data alarms are not displayed,
this could mislead the operator to wrong conclusions and medical decisions!

u 601 u 701 Description

! The result was manually changed.

A A Abnormal result.

Cm Calibration. The microscope check results were no longer valid when the result was generated.

Cs Calibration. The photometer calibration results were no longer valid when the result was
generated.
Cp Calibration. The measuring cell calibration results were no longer valid when the result was
generated.
D Dilution. The result was generated with manually diluted or concentrated sample.

F1 Defocused image found all particle counts are zero.

Review the images and repeat measurement.
F2 Defocused image found, focus position difference is too big.
Review the images and repeat measurement.
F3 Defocused image found, focus position is out of range.
Review the images and repeat measurement.
F4 Defocused image found, MUC count diversity is too big.
Review the images and repeat measurement.
H High temperature. The upper temperature limit has been exceeded.

K The color ranges for CAL parameter were changed.

L Lysed erythrocytes were detected for concentrations ≤50 ERY/μL. (The software cannot reliably
identify hemolyzed erythrocytes in concentrations >50 ERY/μL.
N SG cannot be measured because the sample is too turbid.
(If you work with auto validation and a LIS, the validated results of the other parameters are sent
to the host as usual.)
M The result of the image was manually changed.

O O Parameter is out of range.

P u 601 reduced test profile.

Q Q Invalid QC. QC failed or QC material has expired.

R Test strip cassette onboard stability has expired.

S Sieve result.

T T Trace result. Borderline or "soft positive" result.

Uc The software could not generate an automatic result for all 15 images and at least one of the
images that did not yield a result is crowded.
You need to validate the result manually.
Ub The software could not generate an automatic result for all 15 images and at least one of the
images that did not yield a result contains bubbles.
You need to validate the result manually.
X X A cross-check rule has been triggered.

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u 601 u 701 Description

# # A Roche Service representative did not cancel a service or troubleshooting function, and it can
only be cancelled by a Roche Service representative. All results have this data alarm indication
and the validity of these results cannot be guaranteed. (For example, expired materials may
have been used).
If you find this data alarm indication, contact your Roche Service representative immediately.

6.2 Test number and Test code of u 601

These Test numbers and Test codes belong only to the u 601 results and raw results record.

Test number Test code Description

1 ERY Erythrocytes

2 LEU Leukocytes

3 NIT Nitrite

4 KET Ketones

5 GLU Glucose

6 PRO Protein

7 UBG Urobilinogen

8 BIL Bilirubin

9 COM Compensation field

10 pH pH-Value

20 COL Color

21 CLA Clarity

22 SG Specific Gravity

6.3 Test number and Test code of u 701

These Test numbers and Test codes belong only to the u 701 results and raw results record.

Test number Test code Description

1 RBC Red Blood Cells

3 WBC White Blood Cells

5 NEC Non Squamous Epithelial Cells

6 SEC Squamous Epithelial Cells

7 YEA Yeast

8 CRY Crystals

14 BAC Bacteria

15 HYA Casts - Hyaline

19 SPRM Spermatozoa

21 MUC Mucus

26 PAT Casts - Pathological

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Subclasses
Sub-classes of u701 results are sent:
The “Test number” is created by the system.
The “Test code” is defined by the operator.
e.g. Crystals – Calcium oxalate monohydrate:
Test number Test code Description
8-0 CRY_X Rest of main class CRY
8-1 CaOxm Calcium oxalate monohydrate

6.4 Communication examples

The examples show the sequence of the communications.

6.4.1 Host protocol version 8

Example 1: Upload Sample Results without raw and sediment data
[ENQ]
[ACK]
[STX]1H|\^&|||Instrument·Name^u601^0.17.0^5^201009003^|||||||P|LIS2-A2|20120508125823[CR][ETX]FB[CR][LF]
[ACK]
[STX]2P|1[CR][ETX]3F[CR][LF]
[ACK]
[STX]3O|1|0283|500432^1^Service^SAMPLE|C|R||||||N|||20120508125656|||||||||||F[CR][ETX]AC[CR][LF]
[ACK]
[STX]4R|1|1^ERY|neg^neg^neg^0.00^0.00||International|||F||Service|||u601[CR][ETX]AF[CR][LF]
[ACK]
[STX]5R|2|2^LEU|neg^neg^neg^0.00^0.00||International|||F||Service|||u601[CR][ETX]A8[CR][LF]
[ACK]
[STX]6R|3|3^NIT|pos^pos^pos^0.11^0.11||International|||F||Service|||u601[CR][ETX]FC[CR][LF]
[ACK]
[STX]7C|3|I|A|I[CR][ETX]80[CR][LF]
[ACK]
[STX]0R|4|4^KET|neg^neg^neg^0.00^0.00||International|||F||Service|||u601[CR][ETX]A5[CR][LF]
[ACK]
[STX]1R|5|5^GLU|neg^norm^norm^0.00^0.00||International|||F||Service|||u601[CR][ETX]B0[CR][LF]
[ACK]
[STX]2R|6|6^PRO|neg^neg^neg^0.00^0.00||International|||F||Service|||u601[CR][ETX]B8[CR][LF]
[ACK]
[STX]3R|7|7^UBG|neg^norm^norm^0.00^0.00||International|||F||Service|||u601[CR][ETX]AC[CR][LF]
[ACK]
[STX]4R|8|8^BIL|neg^neg^neg^0.00^0.00||International|||F||Service|||u601[CR][ETX]A4[CR][LF]
[ACK]
[STX]5R|9|10^pH|7^7^7^7.03^7.03||International|||F||Service|||u601[CR][ETX]BB[CR][LF]
[ACK]
[STX]6C|9|I|A|I[CR][ETX]85[CR][LF]
[ACK]
[STX]7R|10|20^COL|Pale·Yellow^Pale·Yellow^Pale·Yellow^^||International|||F||Service|||u601[CR][ETX]52[CR][LF]
[ACK]
[STX]0R|11|21^CLA|Clear^Clear^Clear^^||International|||F||Service|||u601[CR][ETX]69[CR][LF]
[ACK]
[STX]1R|12|22^SG|1.044^1.044^1.044^1.044^1.044||International|||F||Service|||u601[CR][ETX]64[CR][LF]
[ACK]
[STX]1M|1|RC|u601|123456|20121201|20120507|29188300|20121101[CR][ETX]B6[CR][LF]
[ACK]
[STX]2L|1|N[CR][ETX]05[CR][LF]
[ACK]
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[EOT]

Example 2: Upload Sample Results (u601 and u701) with raw data
[ENQ]
[ACK]
[STX]1H|\^&|||Instrument·Name^Cobas6500^0.17.0^5^201009003^601009003|||||||P|LIS2-
A2|20120508133241[CR][ETX]DC[CR][LF]
[ACK]
[STX]2P|1[CR][ETX]3F[CR][LF]
[ACK]
[STX]3O|1|1111|713450^1^Service^SAMPLE|CM|R||||||N|||20120508132753|||||||||||F[CR][ETX]F2[CR][LF]
[ACK]
[STX]4R|1|1^ERY|3+^50·/ul^50·/ul^^||International|||F||Service|||u601[CR][ETX]31[CR][LF]
[ACK]
[STX]5C|1|I|A|I[CR][ETX]7C[CR][LF]
[ACK]
[STX]6R|2|2^LEU|1+^25·/ul^25·/ul^^||International|||F||Service|||u601[CR][ETX]37[CR][LF]
[ACK]
[STX]7C|2|I|S^T|I[CR][ETX]43[CR][LF]
[ACK]
[STX]0R|3|3^NIT|pos^pos^pos^^||International|||F||Service|||u601[CR][ETX]7A[CR][LF]
[ACK]
[STX]1C|3|I|A|I[CR][ETX]7A[CR][LF]
[ACK]
[STX]2R|4|4^KET|4+^150·mg/dl^15·mmol/l^^||International|||F||Service|||u601[CR][ETX]59[CR][LF]
[ACK]
[STX]3C|4|I|A|I[CR][ETX]7D[CR][LF]
[ACK]
[STX]4R|5|5^GLU|2+^100·mg/dl^6·mmol/l^^||International|||F||Service|||u601[CR][ETX]35[CR][LF]
[ACK]
[STX]5C|5|I|A|I[CR][ETX]80[CR][LF]
[ACK]
[STX]6R|6|6^PRO|2+^75·mg/dl^0.75·g/l^^||International|||F||Service|||u601[CR][ETX]1E[CR][LF]
[ACK]
[STX]7C|6|I|A|I[CR][ETX]83[CR][LF]
[ACK]
[STX]0R|7|7^UBG|4+^12·mg/dl^203·umol/l^^||International|||F||Service|||u601[CR][ETX]08[CR][LF]
[ACK]
[STX]1C|7|I|A|I[CR][ETX]7E[CR][LF]
[ACK]
[STX]2R|8|8^BIL|3+^6·mg/dl^100·umol/l^^||International|||F||Service|||u601[CR][ETX]D5[CR][LF]
[ACK]
[STX]3C|8|I|A|I[CR][ETX]81[CR][LF]
[ACK]
[STX]4R|9|10^pH|9^9^9^30.31^30.31||International|||F||Service|||u601[CR][ETX]1A[CR][LF]
[ACK]
[STX]5C|9|I|A|I[CR][ETX]84[CR][LF]
[ACK]
[STX]6R|10|20^COL|Pale·Yellow^Pale·Yellow^Pale·Yellow^^||International|||F||Service|||u601[CR][ETX]51[CR][LF]
[ACK]
[STX]7R|11|21^CLA|Clear^Clear^Clear^^||International|||F||Service|||u601[CR][ETX]70[CR][LF]
[ACK]
[STX]0R|12|22^SG|1.000^1.000^1.000^^||International|||F||Service|||u601[CR][ETX]3B[CR][LF]
[ACK]
[STX]1M|1|RR|u601|1^ERY|REM_ERY_560|72.3800|72.3800[CR][ETX]83[CR][LF]

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[ACK]
[STX]2M|2|RR|u601|1^ERY|REM_ERY_615|65.9000|65.9000[CR][ETX]86[CR][LF]
[ACK]
[STX]3M|3|RR|u601|2^LEU|REM_LEU_560|67.5700|67.5700[CR][ETX]7E[CR][LF]
[ACK]
[STX]4M|4|RR|u601|3^NIT|REM_NIT_560|66.8000|66.8000[CR][ETX]81[CR][LF]
[ACK]
[STX]5M|5|RR|u601|4^KET|REM_KET_560|60.0300|60.0300[CR][ETX]2D[CR][LF]
[ACK]
[STX]6M|6|RR|u601|5^GLU|REM_GLU_560|75.0200|75.0200[CR][ETX]43[CR][LF]
[ACK]
[STX]7M|7|RR|u601|6^PRO|REM_PRO_615|69.2300|69.2300[CR][ETX]61[CR][LF]
[ACK]
[STX]0M|8|RR|u601|7^UBG|REM_UBG_560|71.0800|71.0800[CR][ETX]C7[CR][LF]
[ACK]
[STX]1M|9|RR|u601|8^BIL|REM_BIL_560|72.1600|72.1600[CR][ETX]BE[CR][LF]
[ACK]
[STX]2M|10|RR|u601|10^pH|REM_PH_560|73.1800|73.1800[CR][ETX]46[CR][LF]
[ACK]
[STX]3M|11|RR|u601|10^pH|REM_PH_615|30.3100|30.3100[CR][ETX]3D[CR][LF]
[ACK]
[STX]4M|12|RR|u601|9^COM|REM_COM_465|75.7700|[CR][ETX]64[CR][LF]
[ACK]
[STX]5M|13|RR|u601|9^COM|REM_COM_525|74.3600|[CR][ETX]5D[CR][LF]
[ACK]
[STX]6M|14|RR|u601|9^COM|REM_COM_560|69.2900|[CR][ETX]64[CR][LF]
[ACK]
[STX]7M|15|RR|u601|9^COM|REM_COM_615|72.0400|[CR][ETX]5A[CR][LF]
[ACK]
[STX]0M|16|RR|u601|21^CLA||0.0138|[CR][ETX]5E[CR][LF]
[ACK]
[STX]1M|17|RR|u601|22^SG||1.0001|[CR][ETX]5E[CR][LF]
[ACK]
[STX]2M|1|RC|u601|123456|20121201|20120507|0|00010101[CR][ETX]41[CR][LF]
[ACK]
[STX]3O|1|1111|713450^1^Service^SAMPLE|CM|R||||||N|||20120508132950|||||||||||F[CR][ETX]F2[CR][LF]
[ACK]
[STX]4R|1|19^SPRM|neg^neg^neg^0.0·/HPF^0.0·/ul||International|||F||Service|||u701[CR][ETX]A5[CR][LF]
[ACK]
[STX]5R|2|1^RBC|neg^neg^neg^0.2·/HPF^0.9·/ul||International|||F||Service|||u701[CR][ETX]0E[CR][LF]
[ACK]
[STX]6R|3|3^WBC|neg^neg^neg^1.6·/HPF^7.0·/ul||International|||F||Service|||u701[CR][ETX]1A[CR][LF]
[ACK]
[STX]7R|4|5^NEC|neg^neg^neg^1.1·/HPF^4.8·/ul||International|||F||Service|||u701[CR][ETX]18[CR][LF]
[ACK]
[STX]0R|5|6^SEC|1+^3·/HPF^15·/ul^10.0·/HPF^44.0·/ul||International|||F||Service|||u701[CR][ETX]8F[CR][LF]
[ACK]
[STX]1C|5|I|S^T|I[CR][ETX]45[CR][LF]
[ACK]
[STX]2R|6|7^YEA|neg^neg^neg^0.0·/HPF^0.0·/ul||International|||F||Service|||u701[CR][ETX]1A[CR][LF]
[ACK]
[STX]3R|7|8^CRY|neg^neg^neg^0.0·/HPF^0.0·/ul||International|||F||Service|||u701[CR][ETX]31[CR][LF]
[ACK]
[STX]4R|9|15^HYA|neg^neg^neg^0.0·/HPF^0.0·/ul||International|||F||Service|||u701[CR][ETX]48[CR][LF]
[ACK]

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[STX]5R|10|21^MUC|neg^neg^neg^17.8·/HPF^78.3·/ul||International|||F||Service|||u701[CR][ETX]CC[CR][LF]
[ACK]
[STX]6R|11|26^PAT|neg^neg^neg^0.1·/HPF^0.4·/ul||International|||F||Service|||u701[CR][ETX]7D[CR][LF]
[ACK]
[STX]7R|12|14^BAC|1+^20·/HPF^100·/ul^46.6·/HPF^205.0·/ul||International|||F||Service|||u701[CR][ETX]6D[CR][LF
]
[ACK]
[STX]0C|13|I|S^T|I[CR][ETX]71[CR][LF]
[ACK]
[STX]1M|1|RR|u701|1^RBC|0^0^0^0^0^0^0^0^0^0^0^1^1^0^0|2|0.13|0.88|0.20[CR][ETX]AF[CR][LF]
[ACK]
[STX]2M|2|RR|u701|3^WBC|0^3^0^1^2^1^0^0^0^1^2^3^3^0^0|16|1.07|7.04|1.60[CR][ETX]FF[CR][LF]
[ACK]
[STX]3M|3|RR|u701|5^NEC|1^1^1^0^0^1^0^1^1^0^0^2^2^1^0|11|0.73|4.84|1.10[CR][ETX]ED[CR][LF]
[ACK]
[STX]4M|4|RR|u701|6^SEC|2^6^2^8^11^7^9^6^9^8^11^4^4^4^9|100|6.67|44.00|10.00[CR][ETX]2B[CR][LF]
[ACK]
[STX]5M|5|RR|u701|7^YEA|0^0^0^0^0^0^0^0^0^0^0^0^0^0^0|0|0.00|0.00|0.00[CR][ETX]A3[CR][LF]
[ACK]
[STX]6M|6|RR|u701|8^CRY|0^0^0^0^0^0^0^0^0^0^0^0^0^0^0|0|0.00|0.00|0.00[CR][ETX]D8[CR][LF]
[ACK]
[STX]7M|7|RR|u701|8-1^Ca-Oxm|0^0^0^0^0^0^0^0^0^0^0^0^0^0^0|0|0.00|0.00|0.00[CR][ETX]A8[CR][LF]
[ACK]
[STX]0M|7|RR|u701|14^BAC|33^32^33^31^35^32^22^32^27^31^35^37^37^27^22|466|31.07|205.04|46.60[CR][ETX]43[CR][L
F]
[ACK]
[STX]1M|8|RR|u701|15^HYA|0^0^0^0^0^0^0^0^0^0^0^0^0^0^0|0|0.00|0.00|0.00[CR][ETX]DB[CR][LF]
[ACK]
[STX]2M|9|RR|u701|19^SPRM|0^0^0^0^0^0^0^0^0^0^0^0^0^0^0|0|0.00|0.00|0.00[CR][ETX]41[CR][LF]
[ACK]
[STX]3M|10|RR|u701|21^MUC|10^4^10^10^12^11^17^7^9^10^12^14^14^21^17|178|11.87|78.32|17.80[CR][ETX]B8[CR][LF]
[ACK]
[STX]4M|11|RR|u701|26^PAT|0^0^0^0^0^1^0^0^0^0^0^0^0^0^0|1|0.07|0.44|0.10[CR][ETX]17[CR][LF]
[ACK]
[STX]5M|1|RC|u701|-1|20120508|20120105|-|20120505[CR][ETX]78[CR][LF]
[ACK]
[STX]6L|1|N[CR][ETX]05[CR][LF]
[ACK]
[EOT]

Example 3: Results during multiple measurements

When multiple measurements are switched on, the instrument measure all samples with the same multiple
counts. In this case every sample has more results with one order. When one of the measurements is
finished the result will be sent with the same order and the same barcode.
In the following example the multiple measurement count is 3.

First measurement is finished.

[ENQ]
[ACK]
[STX]1H|\^&|||Instrument·Name^u601^0.17.0^5^201009003^|||||||P|LIS2-A2|20120508130227[CR][ETX]F5[CR][LF]
[ACK]
[STX]2P|1[CR][ETX]3F[CR][LF]
[ACK]
[STX]3O|1|0241|500432^2^Service^SAMPLE|C|R||||||N|||20120508130100|||||||||||F[CR][ETX]93[CR][LF]
[ACK]

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[STX]4R|1|1^ERY|neg^neg^neg^^||International|||F||Service|||u601[CR][ETX]AF[CR][LF]
[ACK]

[STX]0M|1|RC|u601|123456|20121201|20120507|29188300|20121101[CR][ETX]B5[CR][LF]
[ACK]
[STX]1L|1|N[CR][ETX]04[CR][LF]
[ACK]
[EOT]

Second measurement is finished.

[ENQ]
[ACK]
[STX]1H|\^&|||Instrument·Name^u601^0.17.0^5^201009003^|||||||P|LIS2-A2|20120508130248[CR][ETX]F8[CR][LF]
[ACK]
[STX]2P|1[CR][ETX]3F[CR][LF]
[ACK]
[STX]3O|1|0241|500432^2^Service^SAMPLE|C|R||||||N|||20120508130133|||||||||||F[CR][ETX]99[CR][LF]
[ACK]
[STX]4R|1|1^ERY|neg^neg^neg^^||International|||F||Service|||u601[CR][ETX]AF[CR][LF]
[ACK]

[STX]0M|1|RC|u601|123456|20121201|20120507|29188300|20121101[CR][ETX]B5[CR][LF]
[ACK]
[STX]1L|1|N[CR][ETX]04[CR][LF]
[ACK]
[EOT]

Third measurement is finished.

[ENQ]
[ACK]
[STX]1H|\^&|||Instrument·Name^u601^0.17.0^5^201009003^|||||||P|LIS2-A2|20120508130309[CR][ETX]F6[CR][LF]
[ACK]
[STX]2P|1[CR][ETX]3F[CR][LF]
[ACK]
[STX]3O|1|0241|500432^2^Service^SAMPLE|C|R||||||N|||20120508130154|||||||||||F[CR][ETX]9C[CR][LF]
[ACK]
[STX]4R|1|1^ERY|neg^neg^neg^^||International|||F||Service|||u601[CR][ETX]AF[CR][LF]
[ACK]

[STX]0M|1|RC|u601|123456|20121201|20120507|29188300|20121101[CR][ETX]B5[CR][LF]
[ACK]
[STX]1L|1|N[CR][ETX]04[CR][LF]
[ACK]
[EOT]

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Example 4: Upload QC results with raw data

[ENQ]
[ACK]
[STX]1H|\^&|||Instrument·Name^u601^0.17.0^5^201009003^|||||||P|LIS2-A2|20120508131705[CR][ETX]F7[CR][LF]
[ACK]
[STX]2P|1[CR][ETX]3F[CR][LF]
[ACK]
[STX]3O|1|004215/8/2012|500425^1^Service^CONTROL|C|R||||||Q|||20120508131539|||||||||||F[CR][ETX]C7[CR][LF]
[ACK]
[STX]4R|1|1^ERY|neg^neg^neg^^||International|||F||Service|||u601[CR][ETX]AF[CR][LF]
[ACK]
[STX]5R|2|2^LEU|neg^neg^neg^^||International|||F||Service|||u601[CR][ETX]A8[CR][LF]
[ACK]
[STX]6R|3|3^NIT|neg^neg^neg^^||International|||F||Service|||u601[CR][ETX]B6[CR][LF]
[ACK]
[STX]7R|4|4^KET|neg^neg^neg^^||International|||F||Service|||u601[CR][ETX]AC[CR][LF]
[ACK]
[STX]0R|5|5^GLU|neg^norm^norm^^||International|||F||Service|||u601[CR][ETX]AF[CR][LF]
[ACK]
[STX]1R|6|6^PRO|neg^neg^neg^^||International|||F||Service|||u601[CR][ETX]B7[CR][LF]
[ACK]
[STX]2R|7|7^UBG|neg^norm^norm^^||International|||F||Service|||u601[CR][ETX]AB[CR][LF]
[ACK]
[STX]3R|8|8^BIL|neg^neg^neg^^||International|||F||Service|||u601[CR][ETX]A3[CR][LF]
[ACK]
[STX]4R|9|10^pH|7^7^7^^||International|||F||Service|||u601[CR][ETX]BE[CR][LF]
[ACK]
[STX]5C|9|I|A|I[CR][ETX]84[CR][LF]
[ACK]
[STX]6R|10|20^COL|Pale·Yellow^Pale·Yellow^Pale·Yellow^^||International|||F||Service|||u601[CR][ETX]51[CR][LF]
[ACK]
[STX]7R|11|21^CLA|Clear^Clear^Clear^^||International|||F||Service|||u601[CR][ETX]70[CR][LF]
[ACK]
[STX]0R|12|22^SG|1.045^1.045^1.045^^||International|||F||Service|||u601[CR][ETX]68[CR][LF]
[ACK]
[STX]1M|1|RR|u601|1^ERY|REM_ERY_560|72.6300|72.6300[CR][ETX]3D[CR][LF]
[ACK]
[STX]2M|2|RR|u601|1^ERY|REM_ERY_615|66.2800|66.2800[CR][ETX]44[CR][LF]
[ACK]
[STX]3M|3|RR|u601|2^LEU|REM_LEU_560|71.3600|71.3600[CR][ETX]2D[CR][LF]
[ACK]
[STX]4M|4|RR|u601|3^NIT|REM_NIT_560|62.1200|62.1200[CR][ETX]37[CR][LF]
[ACK]
[STX]5M|5|RR|u601|4^KET|REM_KET_560|62.7500|62.7500[CR][ETX]32[CR][LF]
[ACK]
[STX]6M|6|RR|u601|5^GLU|REM_GLU_560|74.8900|74.8900[CR][ETX]45[CR][LF]
[ACK]
[STX]7M|7|RR|u601|6^PRO|REM_PRO_615|70.2000|70.2000[CR][ETX]47[CR][LF]
[ACK]
[STX]0M|8|RR|u601|7^UBG|REM_UBG_560|70.9200|70.9200[CR][ETX]25[CR][LF]
[ACK]
[STX]1M|9|RR|u601|8^BIL|REM_BIL_560|72.2400|72.2400[CR][ETX]17[CR][LF]
[ACK]
[STX]2M|10|RR|u601|10^pH|REM_PH_560|28.7700|28.7700[CR][ETX]20[CR][LF]
[ACK]

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[STX]3M|11|RR|u601|10^pH|REM_PH_615|34.4600|34.4600[CR][ETX]1C[CR][LF]
[ACK]
[STX]4M|12|RR|u601|9^COM|REM_COM_465|78.0500|[CR][ETX]5E[CR][LF]
[ACK]
[STX]5M|13|RR|u601|9^COM|REM_COM_525|76.1700|[CR][ETX]5E[CR][LF]
[ACK]
[STX]6M|14|RR|u601|9^COM|REM_COM_560|72.6800|[CR][ETX]61[CR][LF]
[ACK]
[STX]7M|15|RR|u601|9^COM|REM_COM_615|74.5100|[CR][ETX]5E[CR][LF]
[ACK]
[STX]0M|16|RR|u601|21^CLA||0.0137786177|[CR][ETX]5E[CR][LF]
[ACK]
[STX]1M|17|RR|u601|22^SG||1.04468279631784|[CR][ETX]5E[CR][LF]
[ACK]
[STX]2M|1|RC|u601|123456|20121201|20120507|29188300|20121101|Low_lot|11111|20120531|20120508|1[CR][ETX]47[CR]
[LF]
[ACK]
[STX]3L|1|N[CR][ETX]04[CR][LF]
[ACK]
[EOT]

Example 5: Download (Work list request)

The instrument is always the Master, which means the worklist is requested by the analyzer.
[ENQ]
[ACK]
[STX]1H|\^&|||Instrument·Name^u601^0.17.0^5^201009003^|||||||P|LIS2-A2|20120508132059[CR][ETX]FA[CR][LF]
[ACK]
[STX]2Q|1|^0203^500432^3[CR][ETX]FC[CR][LF]
[ACK]
[STX]3L|1|N[CR][ETX]06[CR][LF]
[ACK]
[EOT]

After sending the request, the instrument is waiting for the answer from the Host:
[ENQ]
[ACK]
[STX]1H|\^&||||Host-01|||||||P|LIS2-A2|20120202143800[CR][ETX]20[CR][LF]
[ACK]
[STX]2O|1|0203|500432^3^Service^SAMPLE|CM|R||||||N|||20120508115956|||||||||||Q[CR][ETX]B2[CR][LF]
[ACK]
[STX]3L|1|N[CR][ETX]06[CR][LF]
[ACK]
[EOT]

Where 0203 is the sample barcode (ID).

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6.4.2 Host protocol version 9

Example 1: 601 result, without raw data transmission and N-flag
[ENQ]
[ACK]
[STX]1H|\^&|||^Cobas6500^2.2.0^9^Unknown^Unknown|||||||P|LIS2-A2|20150616093200[CR][ETX]11[CR][LF]
[ACK]
[STX]2O|1|136|713450^5^Service^SAMPLE|CM|R||||||N|||20150327004636|||||||||||F[CR][ETX]CB[CR][LF]
[ACK]
[STX]3R|1|1^ERY|neg||International|||F||Service||20150327004636|u601[CR][ETX]0D[CR][LF]
[ACK]
[STX]4R|2|2^LEU|25|/uL|International|||F||Service||20150327004636|u601[CR][ETX]23[CR][LF]
[ACK]
[STX]5C|2|I|A|I[CR][ETX]7D[CR][LF]
[ACK]
[STX]6R|3|3^NIT|neg||International|||F||Service||20150327004636|u601[CR][ETX]0F[CR][LF]
[ACK]
[STX]7R|4|4^KET|neg||International|||F||Service||20150327004636|u601[CR][ETX]0B[CR][LF]
[ACK]
[STX]0R|5|5^GLU|norm||International|||F||Service||20150327004636|u601[CR][ETX]8C[CR][LF]
[ACK]
[STX]1R|6|6^PRO|neg||International|||F||Service||20150327004636|u601[CR][ETX]16[CR][LF]
[ACK]
[STX]2R|7|7^UBG|norm||International|||F||Service||20150327004636|u601[CR][ETX]88[CR][LF]
[ACK]
[STX]3R|8|8^BIL|neg||International|||F||Service||20150327004636|u601[CR][ETX]02[CR][LF]
[ACK]
[STX]4R|9|10^pH|7||International|||F||Service||20150327004636|u601[CR][ETX]0B[CR][LF]
[ACK]
[STX]5R|10|20^COL|Pale·yellow||International|||F||Service||20150327004636|u601[CR][ETX]62[CR][LF]
[ACK]
[STX]6C|10|I|K|I[CR][ETX]B7[CR][LF]
[ACK]
[STX]7R|11|21^CLA|Turbid||International|||F||Service||20150327004636|u601[CR][ETX]84[CR][LF]
[ACK]
[STX]0C|11|I|A|I[CR][ETX]A8[CR][LF]
[ACK]
[STX]1R|12|22^SG|1.008||International|||F||Service||20150327004636|u601[CR][ETX]D7[CR][LF]
[ACK]
[STX]2M|1|RC|u601|7777|20151201|20130320|29188300|20121130[CR][ETX]5D[CR][LF]
[ACK]
[STX]3L|1|N[CR][ETX]06[CR][LF]
[ACK]

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Example 2: 601 result with N-flag, without raw data transmission

[ENQ]
[ACK]
[STX]1H|\^&|||^Cobas6500^2.2.0^9^Unknown^Unknown|||||||P|LIS2-A2|20150616093236[CR][ETX]1A[CR][LF]
[ACK]
[STX]2O|1|125|301237^1^Service^SAMPLE|C|R||||||N|||20150326235755|||||||||||F[CR][ETX]7B[CR][LF]
[ACK]
[STX]3R|1|1^ERY|neg||International|||F||Service||20150326235755|u601[CR][ETX]14[CR][LF]
[ACK]
[STX]4R|2|2^LEU|25|/uL|International|||F||Service||20150326235755|u601[CR][ETX]2A[CR][LF]
[ACK]
[STX]5C|2|I|A|I[CR][ETX]7D[CR][LF]
[ACK]
[STX]6R|3|3^NIT|neg||International|||F||Service||20150326235755|u601[CR][ETX]16[CR][LF]
[ACK]
[STX]7R|4|4^KET|neg||International|||F||Service||20150326235755|u601[CR][ETX]12[CR][LF]
[ACK]
[STX]0R|5|5^GLU|norm||International|||F||Service||20150326235755|u601[CR][ETX]93[CR][LF]
[ACK]
[STX]1R|6|6^PRO|0.25|g/L|International|||F||Service||20150326235755|u601[CR][ETX]8A[CR][LF]
[ACK]
[STX]2C|6|I|A|I[CR][ETX]7E[CR][LF]
[ACK]
[STX]3R|7|7^UBG|norm||International|||F||Service||20150326235755|u601[CR][ETX]90[CR][LF]
[ACK]
[STX]4R|8|8^BIL|neg||International|||F||Service||20150326235755|u601[CR][ETX]0A[CR][LF]
[ACK]
[STX]5R|9|10^pH|6.5||International|||F||Service||20150326235755|u601[CR][ETX]75[CR][LF]
[ACK]
[STX]6R|10|20^COL|Pale·yellow||International|||F||Service||20150326235755|u601[CR][ETX]6A[CR][LF]
[ACK]
[STX]7C|10|I|K|I[CR][ETX]B8[CR][LF]
[ACK]
[STX]0R|11|21^CLA|Turbid||International|||F||Service||20150326235755|u601[CR][ETX]84[CR][LF]
[ACK]
[STX]1C|11|I|A|I[CR][ETX]A9[CR][LF]
[ACK]
[STX]2R|12|22^SG|-||International|||F||Service||20150326235755|u601[CR][ETX]15[CR][LF]
[ACK]
[STX]3C|12|I|N|I[CR][ETX]B9[CR][LF]
[ACK]
[STX]4M|1|RC|u601|7777|20151201|20130320|29188300|20121130[CR][ETX]5F[CR][LF]
[ACK]
[STX]5L|1|N[CR][ETX]08[CR][LF]
[ACK]
[EOT]

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Example 3: 601 result with N-flag, with raw data transmission

[ENQ]
[ACK]
[STX]1H|\^&|||^Cobas6500^2.2.0^9^Unknown^Unknown|||||||P|LIS2-A2|20150616093227[CR][ETX]1A[CR][LF]
[ACK]
[STX]2O|1|125|301237^1^Service^SAMPLE|C|R||||||N|||20150326235755|||||||||||F[CR][ETX]7B[CR][LF]
[ACK]
[STX]3R|1|1^ERY|neg||International|||F||Service||20150326235755|u601[CR][ETX]14[CR][LF]
[ACK]
[STX]4R|2|2^LEU|25|/uL|International|||F||Service||20150326235755|u601[CR][ETX]2A[CR][LF]
[ACK]
[STX]5C|2|I|A|I[CR][ETX]7D[CR][LF]
[ACK]
[STX]6R|3|3^NIT|neg||International|||F||Service||20150326235755|u601[CR][ETX]16[CR][LF]
[ACK]
[STX]7R|4|4^KET|neg||International|||F||Service||20150326235755|u601[CR][ETX]12[CR][LF]
[ACK]
[STX]0R|5|5^GLU|norm||International|||F||Service||20150326235755|u601[CR][ETX]93[CR][LF]
[ACK]
[STX]1R|6|6^PRO|0.25|g/L|International|||F||Service||20150326235755|u601[CR][ETX]8A[CR][LF]
[ACK]
[STX]2C|6|I|A|I[CR][ETX]7E[CR][LF]
[ACK]
[STX]3R|7|7^UBG|norm||International|||F||Service||20150326235755|u601[CR][ETX]90[CR][LF]
[ACK]
[STX]4R|8|8^BIL|neg||International|||F||Service||20150326235755|u601[CR][ETX]0A[CR][LF]
[ACK]
[STX]5R|9|10^pH|6.5||International|||F||Service||20150326235755|u601[CR][ETX]75[CR][LF]
[ACK]
[STX]6R|10|20^COL|Pale·yellow||International|||F||Service||20150326235755|u601[CR][ETX]6A[CR][LF]
[ACK]
[STX]7C|10|I|K|I[CR][ETX]B8[CR][LF]
[ACK]
[STX]0R|11|21^CLA|Turbid||International|||F||Service||20150326235755|u601[CR][ETX]84[CR][LF]
[ACK]
[STX]1C|11|I|A|I[CR][ETX]A9[CR][LF]
[ACK]
[STX]2R|12|22^SG|-||International|||F||Service||20150326235755|u601[CR][ETX]15[CR][LF]
[ACK]
[STX]3C|12|I|N|I[CR][ETX]B9[CR][LF]
[ACK]
[STX]4M|1|RR|u601|1^ERY|REM_ERY_615|73.5096|73.5096[CR][ETX]5B[CR][LF]
[ACK]
[STX]5M|2|RR|u601|1^ERY|REM_ERY_560|67.4021|67.4021[CR][ETX]48[CR][LF]
[ACK]
[STX]6M|3|RR|u601|2^LEU|REM_LEU_560|57.1691|57.1691[CR][ETX]49[CR][LF]
[ACK]
[STX]7M|4|RR|u601|3^NIT|REM_NIT_560|65.4398|65.4398[CR][ETX]62[CR][LF]
[ACK]
[STX]0M|5|RR|u601|4^KET|REM_KET_560|56.0789|56.0789[CR][ETX]4F[CR][LF]
[ACK]
[STX]1M|6|RR|u601|5^GLU|REM_GLU_560|73.3669|73.3669[CR][ETX]58[CR][LF]
[ACK]
[STX]2M|7|RR|u601|6^PRO|REM_PRO_615|56.4587|56.4587[CR][ETX]70[CR][LF]
[ACK]

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[STX]3M|8|RR|u601|7^UBG|REM_UBG_560|71.1567|71.1567[CR][ETX]3C[CR][LF]
[ACK]
[STX]4M|9|RR|u601|8^BIL|REM_BIL_560|72.2110|72.2110[CR][ETX]15[CR][LF]
[ACK]
[STX]5M|10|RR|u601|10^pH|REM_PH_615|48.9487|48.9487[CR][ETX]40[CR][LF]
[ACK]
[STX]6M|11|RR|u601|10^pH|REM_PH_560|43.3479|43.3479[CR][ETX]2D[CR][LF]
[ACK]
[STX]7M|12|RR|u601|9^COM|REM_COM_465|74.7436|[CR][ETX]0E[CR][LF]
[ACK]
[STX]0M|13|RR|u601|9^COM|REM_COM_525|73.0516|[CR][ETX]FC[CR][LF]
[ACK]
[STX]1M|14|RR|u601|9^COM|REM_COM_560|68.7292|68.7292[CR][ETX]79[CR][LF]
[ACK]
[STX]2M|15|RR|u601|9^COM|REM_COM_615|71.1831|[CR][ETX]FF[CR][LF]
[ACK]
[STX]3M|16|RR|u601|21^CLA||0.6027|[CR][ETX]C9[CR][LF]
[ACK]
[STX]4M|17|RR|u601|22^SG||-|[CR][ETX]96[CR][LF]
[ACK]
[STX]5M|1|RC|u601|7777|20151201|20130320|29188300|20121130[CR][ETX]60[CR][LF]
[ACK]
[STX]6L|1|N[CR][ETX]09[CR][LF]
[ACK]
[EOT]

Example 4: 701 result without raw data transmission

[ENQ]
[ACK]
[STX]1H|\^&|||^Cobas6500^2.2.0^9^Unknown^Unknown|||||||P|LIS2-A2|20150616084057[CR][ETX]1B[CR][LF]
[ACK]
[STX]2O|1|136|713450^5^Service^SAMPLE|CM|R||||||N|||20150327005518|||||||||||F[CR][ETX]CB[CR][LF]
[ACK]
[STX]3R|1|1^RBC|<5.00|/uL|International|||F||Service||20150327005518|u701[CR][ETX]AA[CR][LF]
[ACK]
[STX]4R|2|3^WBC|11.22|/uL|International|||F||Service||20150327005518|u701[CR][ETX]A8[CR][LF]
[ACK]
[STX]5C|2|I|A|I[CR][ETX]7D[CR][LF]
[ACK]
[STX]6R|3|5^NEC|5|/uL|International|||F||Service||20150327005518|u701[CR][ETX]E8[CR][LF]
[ACK]
[STX]7C|3|I|A|I[CR][ETX]80[CR][LF]
[ACK]
[STX]0R|4|6^SEC|40|/uL|International|||F||Service||20150327005518|u701[CR][ETX]18[CR][LF]
[ACK]
[STX]1C|4|I|A|I[CR][ETX]7B[CR][LF]
[ACK]
[STX]2R|5|7^YEA|neg||International|||F||Service||20150327005518|u701[CR][ETX]06[CR][LF]
[ACK]
[STX]3R|6|8^CRY|neg||International|||F||Service||20150327005518|u701[CR][ETX]18[CR][LF]
[ACK]
[STX]4R|7|14^BAC|150|/uL|International|||F||Service||20150327005518|u701[CR][ETX]6B[CR][LF]
[ACK]
[STX]5C|7|I|A|I[CR][ETX]82[CR][LF]
[ACK]

Global Customer Support

Roche Diagnostics International Ltd 57/66
Host Interface Manual cobas 6500 urine analyzer series

[STX]6R|8|15^HYA|neg||International|||F||Service||20150327005518|u701[CR][ETX]3F[CR][LF]
[ACK]
[STX]7R|9|19^SPRM|neg||International|||F||Service||20150327005518|u701[CR][ETX]A5[CR][LF]
[ACK]
[STX]0R|10|21^MUC|neg||International|||F||Service||20150327005518|u701[CR][ETX]62[CR][LF]
[ACK]
[STX]1R|11|26^PAT|pos||International|||F||Service||20150327005518|u701[CR][ETX]81[CR][LF]
[ACK]
[STX]2C|11|I|A|I[CR][ETX]AA[CR][LF]
[ACK]
[STX]3R|12|0^Others|neg||International|||F||Service||20150327005518|u701[CR][ETX]C4[CR][LF]
[ACK]
[STX]4M|1|RC|u701|1234|20141231|20121211|-1|20150327[CR][ETX]18[CR][LF]
[ACK]
[STX]5M|1|IR|u701|f:&R&cobas_6500_ResultReport_136_27032015005518|Image_136_01^Image_136_02^Image_136_03^Imag
e_136_04^Image_136_06^Image_136_07^Image_136_08^Image_136_09^Image_136_10^Image_136_11^Image_136_12^Image_136
_13^Image_136_14^Image_136_15^Image_136_16|^png|[CR][ETX]D8[CR][LF]
[ACK]
[STX]6L|1|N[CR][ETX]09[CR][LF]
[ACK]
[EOT]

Example 5: Edited 701 result without raw data transmission

[ENQ]
[ACK]
[STX]1H|\^&|||^Cobas6500^2.2.0^9^Unknown^Unknown|||||||P|LIS2-A2|20150616084528[CR][ETX]1E[CR][LF]
[ACK]
[STX]2O|1|136|713450^5^Service^SAMPLE|CM|R||||||N|||20150327005518|||||||||||F[CR][ETX]CB[CR][LF]
[ACK]
[STX]3R|1|1^RBC|<5.00|/uL|International|||F||Service||20150327005518|u701[CR][ETX]AA[CR][LF]
[ACK]
[STX]4C|1|I|M|I[CR][ETX]87[CR][LF]
[ACK]
[STX]5R|2|3^WBC|112.20|/uL|International|||F||Service||20150327005518|u701[CR][ETX]D9[CR][LF]
[ACK]
[STX]6C|2|I|A^!|I[CR][ETX]FD[CR][LF]
[ACK]
[STX]7R|3|5^NEC|5|/uL|International|||F||Service||20150327005518|u701[CR][ETX]E9[CR][LF]
[ACK]
[STX]0C|3|I|A|I[CR][ETX]79[CR][LF]
[ACK]
[STX]1R|4|6^SEC|40|/uL|International|||F||Service||20150327005518|u701[CR][ETX]19[CR][LF]
[ACK]
[STX]2C|4|I|A|I[CR][ETX]7C[CR][LF]
[ACK]
[STX]3R|5|7^YEA|neg||International|||F||Service||20150327005518|u701[CR][ETX]07[CR][LF]
[ACK]
[STX]4R|6|8^CRY|neg||International|||F||Service||20150327005518|u701[CR][ETX]19[CR][LF]
[ACK]
[STX]5R|7|14^BAC|150|/uL|International|||F||Service||20150327005518|u701[CR][ETX]6C[CR][LF]
[ACK]
[STX]6C|7|I|A|I[CR][ETX]83[CR][LF]
[ACK]
[STX]7R|8|15^HYA|neg||International|||F||Service||20150327005518|u701[CR][ETX]40[CR][LF]
[ACK]

Global Customer Support

Roche Diagnostics International Ltd 58/66
Host Interface Manual cobas 6500 urine analyzer series

[STX]0R|9|19^SPRM|neg||International|||F||Service||20150327005518|u701[CR][ETX]9E[CR][LF]
[ACK]
[STX]1R|10|21^MUC|neg||International|||F||Service||20150327005518|u701[CR][ETX]63[CR][LF]
[ACK]
[STX]2R|11|26^PAT|pos||International|||F||Service||20150327005518|u701[CR][ETX]82[CR][LF]
[ACK]
[STX]3C|11|I|A|I[CR][ETX]AB[CR][LF]
[ACK]
[STX]4R|12|0^Others|neg||International|||F||Service||20150327005518|u701[CR][ETX]C5[CR][LF]
[ACK]
[STX]5M|1|RC|u701|1234|20141231|20121211|-1|20150327[CR][ETX]19[CR][LF]
[ACK]
[STX]6M|1|IR|u701|f:&R&cobas_6500_ResultReport_136_27032015005518|Image_136_01^Image_136_02^Image_136_03^Imag
e_136_04^Image_136_06^Image_136_07^Image_136_08^Image_136_09^Image_136_10^Image_136_11^Image_136_12^Image_136
_13^Image_136_14^Image_136_15^Image_136_16|^png|[CR][ETX]D9[CR][LF]
[ACK]
[STX]7L|1|N[CR][ETX]0A[CR][LF]
[ACK]
[EOT]

Example 6: Edited 701 result with subclasses and raw data transmission
[ENQ]
[ACK]
[STX]1H|\^&|||^Cobas6500^2.2.0^9^Unknown^Unknown|||||||P|LIS2-A2|20150616093024[CR][ETX]15[CR][LF]
[ACK]
[STX]2O|1|136|713450^5^Service^SAMPLE|CM|R||||||N|||20150327005518|||||||||||F[CR][ETX]CB[CR][LF]
[ACK]
[STX]3R|1|1^RBC|<5.00|/uL|International|||F||Service||20150327005518|u701[CR][ETX]AA[CR][LF]
[ACK]
[STX]4C|1|I|M|I[CR][ETX]87[CR][LF]
[ACK]
[STX]5R|2|1-0^RBC_X|<5.00|/uL|International|||F||Service||20150327005518|u701[CR][ETX]C1[CR][LF]
[ACK]
[STX]6C|2|I|M|I[CR][ETX]8A[CR][LF]
[ACK]
[STX]7R|3|1-2^RBC1|0.88|/uL|International|||F||Service||20150327005518|u701[CR][ETX]0F[CR][LF]
[ACK]
[STX]0R|4|1-3^RBC2|0.00|/uL|International|||F||Service||20150327005518|u701[CR][ETX]FB[CR][LF]
[ACK]
[STX]1R|5|3^WBC|112.20|/uL|International|||F||Service||20150327005518|u701[CR][ETX]D8[CR][LF]
[ACK]
[STX]2C|5|I|A^!|I[CR][ETX]FC[CR][LF]
[ACK]
[STX]3R|6|5^NEC|5|/uL|International|||F||Service||20150327005518|u701[CR][ETX]E8[CR][LF]
[ACK]
[STX]4C|6|I|A|I[CR][ETX]80[CR][LF]
[ACK]
[STX]5R|7|6^SEC|40|/uL|International|||F||Service||20150327005518|u701[CR][ETX]20[CR][LF]
[ACK]
[STX]6C|7|I|A|I[CR][ETX]83[CR][LF]
[ACK]
[STX]7R|8|7^YEA|neg||International|||F||Service||20150327005518|u701[CR][ETX]0E[CR][LF]
[ACK]
[STX]0R|9|8^CRY|neg||International|||F||Service||20150327005518|u701[CR][ETX]18[CR][LF]
[ACK]

Global Customer Support

Roche Diagnostics International Ltd 59/66
Host Interface Manual cobas 6500 urine analyzer series

[STX]1R|10|14^BAC|150|/uL|International|||F||Service||20150327005518|u701[CR][ETX]92[CR][LF]
[ACK]
[STX]2C|10|I|A|I[CR][ETX]A9[CR][LF]
[ACK]
[STX]3R|11|15^HYA|neg||International|||F||Service||20150327005518|u701[CR][ETX]66[CR][LF]
[ACK]
[STX]4R|12|19^SPRM|neg||International|||F||Service||20150327005518|u701[CR][ETX]CC[CR][LF]
[ACK]
[STX]5R|13|21^MUC|neg||International|||F||Service||20150327005518|u701[CR][ETX]6A[CR][LF]
[ACK]
[STX]6R|14|26^PAT|pos||International|||F||Service||20150327005518|u701[CR][ETX]89[CR][LF]
[ACK]
[STX]7C|14|I|A|I[CR][ETX]B2[CR][LF]
[ACK]
[STX]0R|15|0^Others|neg||International|||F||Service||20150327005518|u701[CR][ETX]C4[CR][LF]
[ACK]
[STX]1M|1|RR|u701|1^RBC|1^0^0^0^0^0^0^0^0^0^0^0^0^0^1|4|0.27|1.76|0.40[CR][ETX]B1[CR][LF]
[ACK]
[STX]2M|2|RR|u701|1-0^RBC_X|0^0^0^0^0^0^0^0^0^0^0^0^0^0^1|2|0.13|0.88|0.20[CR][ETX]BF[CR][LF]
[ACK]
[STX]3M|3|RR|u701|1-2^RBC1|1^0^0^0^0^0^0^0^0^0^0^0^0^0^0|2|0.13|0.88|0.20[CR][ETX]3D[CR][LF]
[ACK]
[STX]4M|4|RR|u701|1-3^RBC2|0^0^0^0^0^0^0^0^0^0^0^0^0^0^0|0|0.00|0.00|0.00[CR][ETX]28[CR][LF]
[ACK]
[STX]5M|5|RR|u701|3^WBC|1^2^3^1^0^0^2^0^0^1^2^0^1^1^3|26|1.73|11.44|2.60[CR][ETX]35[CR][LF]
[ACK]
[STX]6M|6|RR|u701|5^NEC|1^0^1^1^1^1^0^0^0^1^0^1^1^0^2|10|0.67|4.40|1.00[CR][ETX]EE[CR][LF]
[ACK]
[STX]7M|7|RR|u701|6^SEC|7^1^6^7^6^4^1^1^9^7^11^2^7^8^4|81|5.40|35.64|8.10[CR][ETX]AA[CR][LF]
[ACK]
[STX]0M|8|RR|u701|7^YEA|0^0^0^0^0^0^0^0^0^0^0^0^0^0^0|0|0.00|0.00|0.00[CR][ETX]A4[CR][LF]
[ACK]
[STX]1M|9|RR|u701|8^CRY|0^0^0^0^0^0^0^0^2^0^0^0^0^0^0|2|0.13|0.88|0.20[CR][ETX]D0[CR][LF]
[ACK]
[STX]2M|10|RR|u701|14^BAC|32^35^32^32^32^25^35^36^22^32^35^33^32^31^37|481|32.07|211.64|48.10[CR][ETX]66[CR][
LF]
[ACK]
[STX]3M|11|RR|u701|15^HYA|0^0^0^0^0^0^0^0^0^0^0^0^0^0^0|0|0.00|0.00|0.00[CR][ETX]03[CR][LF]
[ACK]
[STX]4M|12|RR|u701|19^SPRM|0^0^0^0^0^0^0^0^0^0^0^0^0^0^0|0|0.00|0.00|0.00[CR][ETX]69[CR][LF]
[ACK]
[STX]5M|13|RR|u701|21^MUC|11^12^4^11^7^29^12^24^17^11^12^10^11^10^14|195|13.00|85.80|19.50[CR][ETX]DA[CR][LF]
[ACK]
[STX]6M|14|RR|u701|26^PAT|1^0^0^1^0^1^0^0^0^1^0^0^1^0^0|5|0.33|2.20|0.50[CR][ETX]27[CR][LF]
[ACK]
[STX]7M|15|RR|u701|0^Others|0^0^0^0^0^0^0^0^0^0^0^0^0^0^0|0|0.00|0.00|0.00[CR][ETX]68[CR][LF]
[ACK]

Global Customer Support

Roche Diagnostics International Ltd 60/66
Host Interface Manual cobas 6500 urine analyzer series

Example 7: 701 result with excluded images

[ENQ]
[ACK]
[STX]1H|\^&|||^Cobas6500^2.2.0^9^Unknown^Unknown|||||||P|LIS2-A2|20150616093544[CR][ETX]1C[CR][LF]
[ACK]
[STX]2O|1|136|713450^5^Service^SAMPLE|CM|R||||||N|||20150327005518|||||||||||F[CR][ETX]CB[CR][LF]
[ACK]
[STX]3R|1|1^RBC|<5.00|/uL|International|||F||Service||20150327005518|u701[CR][ETX]AA[CR][LF]
[ACK]
[STX]4R|2|1-0^RBC_X|<5.00|/uL|International|||F||Service||20150327005518|u701[CR][ETX]C0[CR][LF]
[ACK]
[STX]5R|3|1-2^RBC1|0.00|/uL|International|||F||Service||20150327005518|u701[CR][ETX]FD[CR][LF]
[ACK]
[STX]6R|4|1-3^RBC2|0.00|/uL|International|||F||Service||20150327005518|u701[CR][ETX]01[CR][LF]
[ACK]
[STX]7R|5|3^WBC|12.18|/uL|International|||F||Service||20150327005518|u701[CR][ETX]B4[CR][LF]
[ACK]
[STX]0C|5|I|A|I[CR][ETX]7B[CR][LF]
[ACK]
[STX]1R|6|5^NEC|5|/uL|International|||F||Service||20150327005518|u701[CR][ETX]E6[CR][LF]
[ACK]
[STX]2C|6|I|A|I[CR][ETX]7E[CR][LF]
[ACK]
[STX]3R|7|6^SEC|40|/uL|International|||F||Service||20150327005518|u701[CR][ETX]1E[CR][LF]
[ACK]
[STX]4C|7|I|A|I[CR][ETX]81[CR][LF]
[ACK]
[STX]5R|8|7^YEA|neg||International|||F||Service||20150327005518|u701[CR][ETX]0C[CR][LF]
[ACK]
[STX]6R|9|8^CRY|neg||International|||F||Service||20150327005518|u701[CR][ETX]1E[CR][LF]
[ACK]
[STX]7R|10|14^BAC|150|/uL|International|||F||Service||20150327005518|u701[CR][ETX]98[CR][LF]
[ACK]
[STX]0C|10|I|A|I[CR][ETX]A7[CR][LF]
[ACK]
[STX]1R|11|15^HYA|neg||International|||F||Service||20150327005518|u701[CR][ETX]64[CR][LF]
[ACK]
[STX]2R|12|19^SPRM|neg||International|||F||Service||20150327005518|u701[CR][ETX]CA[CR][LF]
[ACK]
[STX]3R|13|21^MUC|neg||International|||F||Service||20150327005518|u701[CR][ETX]68[CR][LF]
[ACK]
[STX]4R|14|26^PAT|pos||International|||F||Service||20150327005518|u701[CR][ETX]87[CR][LF]
[ACK]
[STX]5C|14|I|A|I[CR][ETX]B0[CR][LF]
[ACK]
[STX]6R|15|0^Others|neg||International|||F||Service||20150327005518|u701[CR][ETX]CA[CR][LF]
[ACK]
[STX]7M|1|RR|u701|1^RBC|^0^0^0^0^0^0^^0^0^0^0^0^0^1|2|0.15|1.02|0.23[CR][ETX]47[CR][LF]
[ACK]
[STX]0M|2|RR|u701|1-0^RBC_X|^0^0^0^0^0^0^^0^0^0^0^0^0^1|2|0.15|1.02|0.23[CR][ETX]55[CR][LF]
[ACK]
[STX]1M|3|RR|u701|1-2^RBC1|^0^0^0^0^0^0^^0^0^0^0^0^0^0|0|0.00|0.00|0.00[CR][ETX]C2[CR][LF]
[ACK]
[STX]2M|4|RR|u701|1-3^RBC2|^0^0^0^0^0^0^^0^0^0^0^0^0^0|0|0.00|0.00|0.00[CR][ETX]C6[CR][LF]
[ACK]

Global Customer Support

Roche Diagnostics International Ltd 61/66
Host Interface Manual cobas 6500 urine analyzer series

[STX]3M|5|RR|u701|3^WBC|^2^3^1^0^0^2^^0^1^2^0^1^1^3|24|1.85|12.18|2.77[CR][ETX]DD[CR][LF]
[ACK]
[STX]4M|6|RR|u701|5^NEC|^0^1^1^1^1^0^^0^1^0^1^1^0^2|9|0.69|4.57|1.04[CR][ETX]71[CR][LF]
[ACK]
[STX]5M|7|RR|u701|6^SEC|^1^6^7^6^4^1^^9^7^11^2^7^8^4|73|5.62|37.06|8.42[CR][ETX]48[CR][LF]
[ACK]
[STX]6M|8|RR|u701|7^YEA|^0^0^0^0^0^0^^0^0^0^0^0^0^0|0|0.00|0.00|0.00[CR][ETX]4A[CR][LF]
[ACK]
[STX]7M|9|RR|u701|8^CRY|^0^0^0^0^0^0^^2^0^0^0^0^0^0|2|0.15|1.02|0.23[CR][ETX]6E[CR][LF]
[ACK]
[STX]0M|10|RR|u701|14^BAC|^35^32^32^32^25^35^^22^32^35^33^32^31^37|413|31.77|209.68|47.65[CR][ETX]AB[CR][LF]
[ACK]
[STX]1M|11|RR|u701|15^HYA|^0^0^0^0^0^0^^0^0^0^0^0^0^0|0|0.00|0.00|0.00[CR][ETX]A1[CR][LF]
[ACK]
[STX]2M|12|RR|u701|19^SPRM|^0^0^0^0^0^0^^0^0^0^0^0^0^0|0|0.00|0.00|0.00[CR][ETX]07[CR][LF]
[ACK]
[STX]3M|13|RR|u701|21^MUC|^12^4^11^7^29^12^^17^11^12^10^11^10^14|160|12.31|81.23|18.46[CR][ETX]08[CR][LF]
[ACK]
[STX]4M|14|RR|u701|26^PAT|^0^0^1^0^1^0^^0^1^0^0^1^0^0|4|0.31|2.03|0.46[CR][ETX]C7[CR][LF]
[ACK]
[STX]5M|15|RR|u701|0^Others|^0^0^0^0^0^0^^0^0^0^0^0^0^0|0|0.00|0.00|0.00[CR][ETX]06[CR][LF]
[ACK]
[STX]6M|1|RC|u701|1234|20141231|20121211|-1|20150327[CR][ETX]1A[CR][LF]
[ACK]
[STX]7M|1|IR|u701|f:&R&cobas_6500_ResultReport_136_27032015005518|Image_136_01^Image_136_02^Image_136_03^Imag
e_136_04^Image_136_06^Image_136_07^Image_136_08^Image_136_09^Image_136_10^Image_136_11^Image_136_12^Image_136
_13^Image_136_14^Image_136_15^Image_136_16|^png|[CR][ETX]DA[CR][LF]
[ACK]
[STX]0L|1|N[CR][ETX]03[CR][LF]
[ACK]
[EOT]

Example 8: 601 result with assigned patient

[ENQ]
[ACK]
[STX]1H|\^&|||^Cobas6500^2.2.0^9^Unknown^Unknown|||||||P|LIS2-A2|20150616093618[CR][ETX]1E[CR][LF]
[ACK]
[STX]2P|1|007|007||Mason^Harry||19620101|M|||||[CR][ETX]52[CR][LF]
[ACK]
[STX]3O|1|136|713450^5^Service^SAMPLE|CM|R||||||N|||20150327004636|||||||||||F[CR][ETX]CC[CR][LF]
[ACK]
[STX]4R|1|1^ERY|neg||International|||F||Service||20150327004636|u601[CR][ETX]0E[CR][LF]
…
[EOT]

Global Customer Support

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Host Interface Manual cobas 6500 urine analyzer series

Example 9: 701 result with unsuccessful image copy

[ENQ]
[ACK]
[STX]1H|\^&|||^Cobas6500^2.2.0^9^Unknown^Unknown|||||||P|LIS2-A2|20150616093804[CR][ETX]1B[CR][LF]
[ACK]
[STX]2P|1|007|007||Mason^Harry||19620101|M|||||[CR][ETX]52[CR][LF]
[ACK]
[STX]3O|1|136|713450^5^Service^SAMPLE|CM|R||||||N|||20150327005518|||||||||||F[CR][ETX]CC[CR][LF]
[ACK]
…
[ACK]
[STX]2M|1|IR|u701|f:&R&cobas_6500_ResultReport_136_27032015005518|Image_136_01^Image_136_02^Image_136_03^Imag
e_136_04^Image_136_06^Image_136_07^Image_136_08^Image_136_09^Image_136_10^Image_136_11^Image_136_12^Image_136
_13^Image_136_14^Image_136_15^Image_136_16|^png|E[CR][ETX]1A[CR][LF]
[ACK]
[STX]3L|1|N[CR][ETX]06[CR][LF]
[ACK]
[EOT]

Example 10: c 6500 result with raw data transmission, subclasses on u 701, excluded image and
assigned patient
[ENQ]
[ACK]
[STX]1H|\^&|||^Cobas6500^2.2.0^9^Unknown^Unknown|||||||P|LIS2-A2|20150616100812[CR][ETX]0F[CR][LF]
[ACK]
[STX]2P|1|007|007||Mason^Harry||19620101|M|||||[CR][ETX]52[CR][LF]
[ACK]
[STX]3O|1|136|713450^5^Service^SAMPLE|CM|R||||||N|||20150327004636|||||||||||F[CR][ETX]CC[CR][LF]
[ACK]
[STX]4R|1|1^ERY|neg||International|||F||Service||20150327004636|u601[CR][ETX]0E[CR][LF]
[ACK]
[STX]5R|2|2^LEU|25|/uL|International|||F||Service||20150327004636|u601[CR][ETX]24[CR][LF]
[ACK]
[STX]6C|2|I|A|I[CR][ETX]7E[CR][LF]
[ACK]
[STX]7R|3|3^NIT|neg||International|||F||Service||20150327004636|u601[CR][ETX]10[CR][LF]
[ACK]
[STX]0R|4|4^KET|neg||International|||F||Service||20150327004636|u601[CR][ETX]04[CR][LF]
[ACK]
[STX]1R|5|5^GLU|norm||International|||F||Service||20150327004636|u601[CR][ETX]8D[CR][LF]
[ACK]
[STX]2R|6|6^PRO|neg||International|||F||Service||20150327004636|u601[CR][ETX]17[CR][LF]
[ACK]
[STX]3R|7|7^UBG|norm||International|||F||Service||20150327004636|u601[CR][ETX]89[CR][LF]
[ACK]
[STX]4R|8|8^BIL|neg||International|||F||Service||20150327004636|u601[CR][ETX]03[CR][LF]
[ACK]
[STX]5R|9|10^pH|7||International|||F||Service||20150327004636|u601[CR][ETX]0C[CR][LF]
[ACK]
[STX]6R|10|20^COL|Pale·yellow||International|||F||Service||20150327004636|u601[CR][ETX]63[CR][LF]
[ACK]
[STX]7C|10|I|K|I[CR][ETX]B8[CR][LF]
[ACK]
[STX]0R|11|21^CLA|Turbid||International|||F||Service||20150327004636|u601[CR][ETX]7D[CR][LF]
[ACK]

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[STX]1C|11|I|A|I[CR][ETX]A9[CR][LF]
[ACK]
[STX]2R|12|22^SG|1.008||International|||F||Service||20150327004636|u601[CR][ETX]D8[CR][LF]
[ACK]
[STX]3M|1|RR|u601|1^ERY|REM_ERY_615|65.7400|65.7400[CR][ETX]4A[CR][LF]
[ACK]
[STX]4M|2|RR|u601|1^ERY|REM_ERY_560|64.7014|64.7014[CR][ETX]4B[CR][LF]
[ACK]
[STX]5M|3|RR|u601|2^LEU|REM_LEU_560|57.6548|57.6548[CR][ETX]54[CR][LF]
[ACK]
[STX]6M|4|RR|u601|3^NIT|REM_NIT_560|60.8798|60.8798[CR][ETX]67[CR][LF]
[ACK]
[STX]7M|5|RR|u601|4^KET|REM_KET_560|56.3708|56.3708[CR][ETX]4A[CR][LF]
[ACK]
[STX]0M|6|RR|u601|5^GLU|REM_GLU_560|66.6362|66.6362[CR][ETX]4D[CR][LF]
[ACK]
[STX]1M|7|RR|u601|6^PRO|REM_PRO_615|59.7865|59.7865[CR][ETX]79[CR][LF]
[ACK]
[STX]2M|8|RR|u601|7^UBG|REM_UBG_560|70.8192|70.8192[CR][ETX]3B[CR][LF]
[ACK]
[STX]3M|9|RR|u601|8^BIL|REM_BIL_560|68.3156|68.3156[CR][ETX]34[CR][LF]
[ACK]
[STX]4M|10|RR|u601|10^pH|REM_PH_615|47.2376|47.2376[CR][ETX]29[CR][LF]
[ACK]
[STX]5M|11|RR|u601|10^pH|REM_PH_560|42.4714|42.4714[CR][ETX]1C[CR][LF]
[ACK]
[STX]6M|12|RR|u601|9^COM|REM_COM_465|73.7436|[CR][ETX]0C[CR][LF]
[ACK]
[STX]7M|13|RR|u601|9^COM|REM_COM_525|71.8775|[CR][ETX]10[CR][LF]
[ACK]
[STX]0M|14|RR|u601|9^COM|REM_COM_560|67.8806|67.8806[CR][ETX]7A[CR][LF]
[ACK]
[STX]1M|15|RR|u601|9^COM|REM_COM_615|70.1842|[CR][ETX]FF[CR][LF]
[ACK]
[STX]2M|16|RR|u601|21^CLA||0.5221|[CR][ETX]C3[CR][LF]
[ACK]
[STX]3M|17|RR|u601|22^SG||1.0077|[CR][ETX]95[CR][LF]
[ACK]
[STX]4M|1|RC|u601|7777|20151201|20130320|29188300|20121130[CR][ETX]5F[CR][LF]
[ACK]
[STX]5L|1|N[CR][ETX]08[CR][LF]
[ACK]
[EOT]
[ENQ]
[ACK]
[STX]1H|\^&|||^Cobas6500^2.2.0^9^Unknown^Unknown|||||||P|LIS2-A2|20150616100814[CR][ETX]11[CR][LF]
[ACK]
[STX]2P|1|007|007||Mason^Harry||19620101|M|||||[CR][ETX]52[CR][LF]
[ACK]
[STX]3O|1|136|713450^5^Service^SAMPLE|CM|R||||||N|||20150327005518|||||||||||F[CR][ETX]CC[CR][LF]
[ACK]
[STX]4R|1|1^RBC|<5.00|/uL|International|||F||Service||20150327005518|u701[CR][ETX]AB[CR][LF]
[ACK]
[STX]5R|2|1-0^RBC_X|<5.00|/uL|International|||F||Service||20150327005518|u701[CR][ETX]C1[CR][LF]
[ACK]

Global Customer Support

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Host Interface Manual cobas 6500 urine analyzer series

[STX]6R|3|1-2^RBC1|0.00|/uL|International|||F||Service||20150327005518|u701[CR][ETX]FE[CR][LF]
[ACK]
[STX]7R|4|1-3^RBC2|0.00|/uL|International|||F||Service||20150327005518|u701[CR][ETX]02[CR][LF]
[ACK]
[STX]0R|5|3^WBC|12.18|/uL|International|||F||Service||20150327005518|u701[CR][ETX]AD[CR][LF]
[ACK]
[STX]1C|5|I|A|I[CR][ETX]7C[CR][LF]
[ACK]
[STX]2R|6|5^NEC|5|/uL|International|||F||Service||20150327005518|u701[CR][ETX]E7[CR][LF]
[ACK]
[STX]3C|6|I|A|I[CR][ETX]7F[CR][LF]
[ACK]
[STX]4R|7|6^SEC|40|/uL|International|||F||Service||20150327005518|u701[CR][ETX]1F[CR][LF]
[ACK]
[STX]5C|7|I|A|I[CR][ETX]82[CR][LF]
[ACK]
[STX]6R|8|7^YEA|neg||International|||F||Service||20150327005518|u701[CR][ETX]0D[CR][LF]
[ACK]
[STX]7R|9|8^CRY|neg||International|||F||Service||20150327005518|u701[CR][ETX]1F[CR][LF]
[ACK]
[STX]0R|10|14^BAC|150|/uL|International|||F||Service||20150327005518|u701[CR][ETX]91[CR][LF]
[ACK]
[STX]1C|10|I|A|I[CR][ETX]A8[CR][LF]
[ACK]
[STX]2R|11|15^HYA|neg||International|||F||Service||20150327005518|u701[CR][ETX]65[CR][LF]
[ACK]
[STX]3R|12|19^SPRM|neg||International|||F||Service||20150327005518|u701[CR][ETX]CB[CR][LF]
[ACK]
[STX]4R|13|21^MUC|neg||International|||F||Service||20150327005518|u701[CR][ETX]69[CR][LF]
[ACK]
[STX]5R|14|26^PAT|pos||International|||F||Service||20150327005518|u701[CR][ETX]88[CR][LF]
[ACK]
[STX]6C|14|I|A|I[CR][ETX]B1[CR][LF]
[ACK]
[STX]7R|15|0^Others|neg||International|||F||Service||20150327005518|u701[CR][ETX]CB[CR][LF]
[ACK]
[STX]0M|1|RR|u701|1^RBC|^0^0^0^0^0^0^^0^0^0^0^0^0^1|2|0.15|1.02|0.23[CR][ETX]40[CR][LF]
[ACK]
[STX]1M|2|RR|u701|1-0^RBC_X|^0^0^0^0^0^0^^0^0^0^0^0^0^1|2|0.15|1.02|0.23[CR][ETX]56[CR][LF]
[ACK]
[STX]2M|3|RR|u701|1-2^RBC1|^0^0^0^0^0^0^^0^0^0^0^0^0^0|0|0.00|0.00|0.00[CR][ETX]C3[CR][LF]
[ACK]
[STX]3M|4|RR|u701|1-3^RBC2|^0^0^0^0^0^0^^0^0^0^0^0^0^0|0|0.00|0.00|0.00[CR][ETX]C7[CR][LF]
[ACK]
[STX]4M|5|RR|u701|3^WBC|^2^3^1^0^0^2^^0^1^2^0^1^1^3|24|1.85|12.18|2.77[CR][ETX]DE[CR][LF]
[ACK]
[STX]5M|6|RR|u701|5^NEC|^0^1^1^1^1^0^^0^1^0^1^1^0^2|9|0.69|4.57|1.04[CR][ETX]72[CR][LF]
[ACK]
[STX]6M|7|RR|u701|6^SEC|^1^6^7^6^4^1^^9^7^11^2^7^8^4|73|5.62|37.06|8.42[CR][ETX]49[CR][LF]
[ACK]
[STX]7M|8|RR|u701|7^YEA|^0^0^0^0^0^0^^0^0^0^0^0^0^0|0|0.00|0.00|0.00[CR][ETX]4B[CR][LF]
[ACK]
[STX]0M|9|RR|u701|8^CRY|^0^0^0^0^0^0^^2^0^0^0^0^0^0|2|0.15|1.02|0.23[CR][ETX]67[CR][LF]
[ACK]
[STX]1M|10|RR|u701|14^BAC|^35^32^32^32^25^35^^22^32^35^33^32^31^37|413|31.77|209.68|47.65[CR][ETX]AC[CR][LF]

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Host Interface Manual cobas 6500 urine analyzer series

[ACK]
[STX]2M|11|RR|u701|15^HYA|^0^0^0^0^0^0^^0^0^0^0^0^0^0|0|0.00|0.00|0.00[CR][ETX]A2[CR][LF]
[ACK]
[STX]3M|12|RR|u701|19^SPRM|^0^0^0^0^0^0^^0^0^0^0^0^0^0|0|0.00|0.00|0.00[CR][ETX]08[CR][LF]
[ACK]
[STX]4M|13|RR|u701|21^MUC|^12^4^11^7^29^12^^17^11^12^10^11^10^14|160|12.31|81.23|18.46[CR][ETX]09[CR][LF]
[ACK]
[STX]5M|14|RR|u701|26^PAT|^0^0^1^0^1^0^^0^1^0^0^1^0^0|4|0.31|2.03|0.46[CR][ETX]C8[CR][LF]
[ACK]
[STX]6M|15|RR|u701|0^Others|^0^0^0^0^0^0^^0^0^0^0^0^0^0|0|0.00|0.00|0.00[CR][ETX]07[CR][LF]
[ACK]
[STX]7M|1|RC|u701|1234|20141231|20121211|-1|20150327[CR][ETX]1B[CR][LF]
[ACK]
[STX]0M|1|IR|u701|f:&R&cobas_6500_ResultReport_136_27032015005518|Image_136_01^Image_136_02^Image_136_03^Imag
e_136_04^Image_136_06^Image_136_07^Image_136_08^Image_136_09^Image_136_10^Image_136_11^Image_136_12^Image_136
_13^Image_136_14^Image_136_15^Image_136_16|^png|[CR][ETX]D3[CR][LF]
[ACK]
[STX]1L|1|N[CR][ETX]04[CR][LF]
[ACK]
[EOT]

Global Customer Support

Roche Diagnostics International Ltd 66/66