June 2017 (v3) MS - Paper 4 CIE Biology IGCSE
June 2017 (v3) MS - Paper 4 CIE Biology IGCSE
June 2017 (v3) MS - Paper 4 CIE Biology IGCSE
BIOLOGY 0610/43
Paper 4 Theory (Extended) May/June 2017
MARK SCHEME
Maximum Mark: 80
Published
This mark scheme is published as an aid to teachers and candidates, to indicate the requirements of the
examination. It shows the basis on which Examiners were instructed to award marks. It does not indicate the
details of the discussions that took place at an Examiners’ meeting before marking began, which would have
considered the acceptability of alternative answers.
Mark schemes should be read in conjunction with the question paper and the Principal Examiner Report for
Teachers.
Cambridge will not enter into discussions about these mark schemes.
Cambridge is publishing the mark schemes for the May/June 2017 series for most Cambridge IGCSE®,
Cambridge International A and AS Level and Cambridge Pre-U components, and some Cambridge O Level
components.
This syllabus is approved for use in England, Wales and Northern Ireland as a Cambridge International Level 1/Level 2 Certificate.
1(a)(i) arrow / (s) from a vena cava through atria and into right ventricle ; 1
1(a)(ii) C, aorta ; 1
1(b)(ii) stop back-flow (of blood) / ensure (blood) flows one way ; 1 I pressure changes
1(d) 1 septum ; 2
either
2 separates oxygenated and deoxygenated blood ;
or
3 to allow a double circulation ;
ribosome to max 1
4 site of, protein synthesis ; (‘protein synthesis’ is in question)
5 ribosome assembles amino acids into proteins ;
6 passes through the ribosome / reads mRNA ;
2(d)(i) 1 temperature ; 2
2 surface area of substrate ;
3 concentration / volume / amount / number, of enzyme (solution) ;
4 concentration / volume / amount, of (named) substrate (solution) ;
5 type of enzyme ;
6 type of substrate ;
3(a) description 6
1 (stem) cells divide ; MP1 I reproduce
2 by mitosis ;
3 to form, daughter / genetically identical, cells ;
4 nucleus buds off / AW ; MP4 A no nucleus (in mature red
5 digested / broken down, mitochondria ; blood cell)
6 only one of stem cells specialises / others continue to be stem cells ; MP5 A no mitochondria (in mature red
blood cell)
adaptations
7 haemoglobin made prior to, mitochondria / nucleus removed / maturation ; MP7 must be in correct place in
8 (loss of structures) gives space for, oxygen transport / haemoglobin ; sequence of events
9 haemoglobin, transports / AW, oxygen ; MP8 A volume for space, I area
10 biconcave shape / described ; MP12 I ref to gas exchange
11 large surface area (to volume ratio) ;
12 for diffusion of oxygen / gas(es) ;
13 AVP ;
3(b) plasma ; 1
4(e) 1 to prevent extinction (of many species) / maintain (bio)diversity ; 3 MP 1 A saves many species
2 ref to preventing disruption of food, chains / web ; MP 4 examples
3 provide, habitats (for shelter / breeding grounds / AW) for many species ; • ref to flooding / natural
4 and 5 ecosystems provide, ‘service’, for humans ; ; disasters
6 idea of areas for, recreation / (eco)tourism / education ; • ref to nutrients cycle
7 ethical reasons / aesthetic reasons / AW ; • ref to maintenance of water
cycle
• ref to greenhouse
gas / carbon storage / carbon
sink waste disposal
• provide,
resources / food / fuel / drugs /
raw materials / building
materials
• provide genes (for selective
breeding / genetic
engineering)
5(a)(iii) eutrophication ; 1
5(c) 1 some species compete much better than others / better at obtaining 2 MP 2 I competition for mates
(named) resource(s) ;
2 competition for, light / water / nutrients / space / AW ;
3 some species grow faster ;
4 example of grassland, adaptions / fast growth ; MP 4 examples: taller stems / larger
5 better at using ions released by fertiliser ; leaves / longer roots
6 more ‘robust’ / less successful at combating disease or pests ;
7 some cannot survive grazing by grassland herbivores / AW ;
8 ref to adaptations ;
6(c)(i) 1 (vaccine contains) harmless / attenuated / dead / AW, form of, (named) 4
pathogen / antigen ;
2 (antigens / vaccine) stimulate an immune response ;
3 ref to lymphocytes ;
4 lymphocytes / white blood cells, make antibodies ;
5 ref to specificity ;
6 production of memory cells ;
7 rapid, immune response / AW, if exposed to same, pathogen / antigen ;
8 gives long-term immunity ;
9 AVP ;