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PROFF 1 MCQS 2021

1)65yo female, 5 year history of increasing pain and stiffness of hip. This
gradually worsened and no longer responds to simple analgesics. Appropriate
imaging modality to diagnose?
cord, cancer
a) CT -> Brain, spinal

ligaments, joints, organs

b)MRI* soft tissue injuries,
->

stones
c)Ultrasound ->
organs, gallstones, kidney
d)X-ray -> Bones

2)Radiological intervention to rule out muscle spasm?

a)CT
b)MRI*
c)X-ray
D)ultrasound

3)Mechanism of swelling of knee joint?

a)haemarthrosis
b)transudate
c)exudate*
D)edema

4)Condition which decreases absorption of calcium?

a)Hyperparathyroidism
b) steatorrhoea
c)gastric acidity
d)hypophosphatemia(*)

5)4 months pregnant woman w vaginal bleeding and⑳ increased hCG. Placental
membranes seen without -
inner cell mass. Diagnosis:
a) Hyatidiform mole(*)
b)Ectopic pregnancy
c)Placenta previa
d)Endometriosis
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6)Cervical Biopsy of 55yo female shows stratified squamous epithelium in

place of columnar epithelium in endo-cervic. Underlying mechanism of this
change is?
a) increase in cytosolic protein
b) reprogramming of stem cells(*)
c) increase in uniquitone-proteosome activity
d) increased synthesis of cytosolic proteins

7)A boy fell from roof and get and injury on lateral surface of arm while his arm
was adducted..which mucle is responsible for this movement
A. Latissimus Dorsi(*)
B.pect. minor
C. Seratus anterior

8)N.acetylneraminic acid a 9 carbon sugar acid is present in

A. Cerebrosides
B.globosides
C.gangliosides(*)

9)delivery of placenta occurs after

20 mins
30 mins
40 mins(*)

10)cytochrome p450 enzymes ocuur on the outer surface of

RER(*)
SER
Golgi apparatus
Ribosomes

11)Lateral rotation at hip joint is caused by which muscle

A) piriformis(*)
B)gluteus maximus
C)gluteus med
D)Tensor fascia lata

12)Glycerophospholipid is a lipid.which belongs to it?

A)Cardiolipin(*)
B) gangliosode
C) cerebroside
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13)Ceruloplasmin is a type of protein.....

Storage
Transport.
- inner mitochondrial membrane

14)Which type of phospholipid is present in membrane.....

Cardiolipin(*)
Sphingomylin
Lecithin

15)Transposition of thorax and abdomen viscera. Name of defect:

A) situs inversus(*)
B) Kartagener syndrome
C) Sirenomelia

16)Which of the following cells are seen in Howship lacunae?

A) Osteoblasts
B)Osteoclasts(*)
C) chondrocytes
17) child having syndactyly dr said it can be cured surgically.why does
Syndactly occured? (Fused Digits)

18)sperms survive for how long(3-5 days)

19)Which of the following is characteristic of partial agonists?

a) maximum affinity with minimal effect
b) minimal affinity with minimal effect
c) antagonist activity in presence of agonist(*)
d) synergistic activity in presence of agonist
e) minimal affinity with maximum effect

20).HCG RELEASED BY?

TROPHOBLAST
Synchgiotophoblast
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21) action potentials differ in cardiac muscle and skeletal muscle, a plateau is
observed in cardiac muscle potential due to:
a) fast sodium channels
b) slow calcium channels(*)
c) fast calcium channels
d) slow sodium channels

22)Which cell junction is present between cells and is most apical in position?
A. Gap junctions
B. Hemi desmosomes
C. Tight junctions(*)
D. Desmosomes

23)Fracture of humerus, radial groove injury. Loss of sensation in what area of

hand?
Ans. Dorsum of lateral 3.5 fingers

24)Sex of the embryo is determined when PGD’s migrate from yolk sac to
developing gonads . From where do these PGD’s migrate from ?
A. Epiblast(*)
B.notochord epiblast to yolksack -> Developing goneds
25)Alkalanization of urine is done when there is ovedosage or toxicity of a drug
which is a weak acid this is done to ?
A. Increase the tubular resorption of the drug
B. Decrease the tubular resorption of drug(*)

26)Which of following are wandering/ transient cells

Fibroblast
Mast cells(*)

27)Intercalated disc of cardiac myocytes have which junctions ?

•Desmosomes and tight junctions
•Desmosomes and gap junctions (*)

28)Which Connective Tissue forms scar after wound /surgery repair :

(adipocytes, plasma cells, fibro*, mast cells)
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29)*Palmar surface, lateral 3 and half fingers & atrophy of thenar eminance
Which space affected?
(thernar, midpalmar,....)

30)Eicosanoids contain a wide range of compounds with varied physiological

functions. Which one of the following is involved in blood clotting?
a) PGE
b) PGFa2
c)Prostacyclin -> Anticlotting
d) thromboxane A2(*)
clotting
31)A body builder while exercising does push-ups by bringing his scapula close
to his spine and midline. Which muscle is involved in the following activity?
a) Levator Scapula
b) Latissimus dorsi
c) Subscapularis
d) Rhomboids(*)

32)Nerve supply of dorsal surface of lateral 3 and a half digits(Radial Nerve)

33) Effect for enhanced drug absorption

Isoniazid a drug for treatment of tuberculosis…cause deficiency of which
vitamin( B1) Phenylalanini.

V
&
leucine
Toyptophane
->
valine
->

-> Faverwine
-> Isoleucine
34) Which of the following is essential amino acid I methionine
Histamine
PTV-TIM- HALL ↳ Argroniand
35) Most abundant collagen in Hyaline cartilage (type 2)

36) Amino acid present in core protein of nucleosomes(histone)

37) Connective tissue in saphenous opening?

(Cribriform) superficial fasci
->

38) Floor of cubital fossa?

(brachialis and Supinator)

39) Drugs that induce cyp450?

Rifampin
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40) Drugs that inhibit cyp?

Ketoconazole.

41) Which ion is more in intracellular fluid?(K)

42) Which ion is in greater conc. In extracellular fluid?(Na)

43) Which nerve passes on medial side of psoas/piriformis muscle and supplies
what?
(Obturator N)

44) Butcher accidently cut his palm…deep cutaneous nerve is damaged..this

nerve is a branch of
1) median nerve
2)ulnar(*)
3)radial
4)axillary

45)Which Muscle is inserted in greater tuberosity?

1)Suprascapular
2)supraspinatous…etc
3) Subscapularis (*)

46) Lateral branch of brachial plexus pierces which muscle of anterior compart.
Of arm?
1) long head of bicep
2) short head of bicep
3) coracobrachialis
4) brachialis(*)

47) Blister formation occurs because of dysfunction of which Junction?

Zona occludens
Desmosomes
hemiDesmosomes(*)
zona adherens

48) rationale for drug holiday

Ans. Tachyphylaxis
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49) neurotransmitters involved in pain

- bradykinin*
-substance p
-glycine

50)Lymphatic drainage of skin covering medial aspect of knee

joint…(Superficial Inguinal Lymph Nodes)

51) A child after eating icecream start vomiting..others symptoms are cramps
and diarrhea,,,Tell the enzymatic deficiency.
Ans. Lactase

52) At which age of fetus the congenital abnormalities are most likely to occur?
5-8 weeks*
10-15 weeks

53)Which ions cause both repolarization and depolarization? (Na)

54)Transport of calcium occurs through?

Simple diffusion
Facilitated
Primary active(*)
Secondary active

55)Nailbed of index finger is supplied by which nerve….

Radial
Median(*)
Ulnar
Ans?

56) Intermediate embryonic mesoderm derivatives

Kidney and gonads(*)
Bladder and gonads
Prostate and duodenum

57) Capacitation takes place in

Ans. 7 Hours
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58) How much sperm stay in cervix

Ans. 1%

59) Utero placental circulation starts at

Ans. 13th Day