Differential of Short Cases

DIFFERENTIAL FOR SHORT CASES IN PEDIATRICS
By Dr Muhammad Sajid Sabir … Edited by Dr Kalim Marwat

KEY WORDS: Liver = L, Spleen = S, Jaundice = J, Pallor = P, Anemia = A,
Lymph Node = LN, HSM = Hepatosplenomegaly, Present = +ve, Absent = -ve
1. Jaundice +ve, Liver +ve, Spleen -ve

a) Acute Viral Hepatitis
b) Wilson disease
c) Autoimmune Hepatitis
d) Drug induced Hepatitis
2. Jaundice –ve, Liver & Spleen (HSM) +ve,

a) Enteric fever
b) Malaria
c) TB
d) Leukemia
e) Lymphoma
3. Jaundice +ve, Liver & Spleen (HSM) +ve

a) Chronic Viral Hepatitis (HBV, HCV)
b) Autoimmune Hepatitis
c) Wilson Disease
d) Acute Viral Hepatitis (HAV)
e) Enteric hepatitis
f) Malaria
4. Jaundice +ve, Spleen +ve, Anemia +/- ve, Liver –ve

a) Hemolytic anemia like Hereditary Spherocytosis, G6PD Def (Chronic), Eliptocytosis
b) Malaria
c) CLD (may be without stigmata)
d) Autoimmune Hemolytic Anemia (AHA)
e) Enteric Hepatitis
5. LN +ve, Liver & Spleen (HSM) +ve

a) TB
b) Leukemia
c) Lymphoma
d) Infectious mononucleosis
e) IEMs like Gaucher Disease,
1
6. Anemia +ve, Spleen +ve
a) Malaria
b) CLD
c) Leukemia
d) Lymphoma
e) Gaucher Disease
7. Anemia +ve, Liver & Spleen (HSM) +ve

a) Thalassemia
b) Leukemia / lymphoma
c) Chronic Hemolytic Anemia (AHA, Fanconi anemia)
d) Malaria
e) Disseminated TB
f) HLH
8. Splenomegaly only
a) Malaria
b) Enteric fever
c) CLD (may be without stigmata)
d) Leukemia/ Lymphoma
e) Thalassemia
f) Lipid storage disorder (Gaucher disease, NPD)
g) Others: JRA, SLE, Hereditary Spherocytosis
h) Infective endocarditis with murmur
9. Hepatomegaly only
a) GSD
b) Liver Tumors
 Hepatoblastoma
 Hepatoma
 Hemangioma
c) Wilson disease
d) Cong. Hepatic fibrosis – rare
e) CCF – rare & present with other signs
f) Liver Abscess … patient is toxic
10. Anemia only (HSM –ve)

a) Nutritional Anemia (Iron, Folate, B12 Def)
b) Aplastic Anemia
c) Malaria
d) Acute Blood Loss
e) Leukemia
2
11. Lymphadenopathy only
a) TB
b) Leukemia
c) Lymphoma
d) Histocytosis
e) Recurrent URTI
12. D/Ds of Thalassemia All are transfusion-dependent anemias

a) β Thalassemia Major
b) Sickle β Thalassemia
c) Autoimmune Hemolytic Anemia
d) Cong. Dyserythropoetic Anemia
e) Unstable Hemoglobin Syndrome
13. D/Ds of HSP

a) HSP
b) ITP
c) Aplastic Anemia
d) Platelet Function Disorder
e) Leukemia
f) Infections Rash like SSSS, Scarlet fever etc
14. CLDs
a) Chronic Viral Hepatitis (HBV, HCV)
b) Autoimmune Hepatitis
c) Wilson Disease
d) α - 1 – Antitrypsin Def
Rare
e) GSD – IV
f) NPD type II
g) Galactosemia
15. Persistent Neonatal Jaundice(Direct)

a) Cong. Biliary Atresia
b) Idiopathic Neonatal Hepatitis
c) Galactosemia
d) TORCH infections
e) PFIC
f) Choledoocal Cyst
g) α - 1 – Antitrypsin Def
3
16. D/Ds of Portal Hypertension
a) Cirrhosis of Liver:
 Chronic Viral Hepatitis (HBV, HCV)
 Autoimmune Hepatitis
 Wilson Disease
 α - 1 – Antitrypsin Def
b) Cong. Hepatic Fibrosis
c) Budd – Chiari Syndrome
17. Obesity
a) Simple obesity
b) Cushing Syndrome
c) Hypopituitarism
d) Hypothyroidism
e) Syndromes:
 Prader – Willi Syndrome
 Bardet – Biedle Syndrome
18. D/Ds of Petechi

a) ITP
b) Aplastic Anemia
c) HSP
d) Leukemia
e) Platelet Function Disorder
f) Type 2N (platelet type) vWD
19. D/Ds of Bruises

a) Hemophilia
b) vWD
c) other clotting Factors deficiencies like Vit K, DIC or cong.
d) Trauma
e) Non – accidental injuries
f) Complications of CLD
20. D/Ds Bowed Legs

a) Nutritional Rickets
b) Hypophosphatemic Rickets
c) Metephysal Dysplasia
d) Blount Disease
e) Chrondoplasia
f) MPS type IV
g) RTA type II & Type I (due to phosphaturia)
4
21. D/Ds of Short Stature …
I. THIN
a) Constitutional
b) Genetic
c) Growth Hormone def
d) Celiac Disease
e) Crohn Disease
II. FAT
a) Cushing Syndrome
b) Hypothyroidism
c) Growth Hormone Def
d) Hypopituitarism
e) Pseudo-hypoparathyroidism
f) Other syndromes like Prader – Willi syndrome, Turner syndrome
22. Monoarthritis
a) Septic Arthritis … with fever
b) Monarticular JIA
c) Reactive Arthritis
d) Joint bleed
e) TB Arthritis
f) Trauma
g) Transient Arthritis … without Fever
23. Very Painful Monoarthritis

a) Septic Arthritis
b) Rheumatic Fever
c) Heamarthosis
d) Osteomyelitis
e) Trauma
24. Acidotic Breathing

a) CRF
b) RTA
c) DKA
d) Drug Ingestion
e) IEMs
f) Sepsis
5
25. D/Ds of Large Head
I. With Hydrocephalus
a) Acquired stenosis
b) Dandy Walker Syndrome
c) Arnold – Chiari Malformation
d) Post – Meningetic Sequale
e) TBM
f) Tumor
II. Without Hydrocephalus

a) Familial
b) Rickets
c) Achondroplasia
d) Canavan Disease
e) Alexander Disease
f) GM1 – Gangliosidosis
g) Tay – Sachs Disease
h) Sandhoff Disease
26. Chorea
a) Rheumatic Chorea
b) SLE
c) Wilson Disease
d) Drug Induced
27. Dystonia
a) Wilson disease
b) Hallervorden – Spatz Disease
c) Kernicterus
d) Effect of Birth Asphyxia
e) Drugs
28. Paraplegia – Spastic

a) Spinal Mass
 Tumor
 TB
b) Syringomyelia
c) Recovery Phase of Transverse Myelitis
6
29. Quadriplegia … Spastic
a) CP
b) Post – Meningetic Sequale
c) Neurodegenerative disorder
 ALD
 SSPE
 Wilson Disease
 Hallervorden Disease
30. Hemiplegia
a) CP
b) Post – Meningetic Sequale
c) Congenital Malformation e.g. porencephalic cyst
d) Intracranial Hemorrhage
 Bleeding disorder
 Trauma
e) Stroke – Thromboembolism
 Protein C & S Def
 CHD
 Sickle Cell Disease
 Acute Hemiplegia of childhood
31. Quadriplegia … Flaccid

a) Polio
b) GBS
c) Transvers Myelitis
d) Botulism
e) Spinal Shock
f) MLD
g) Hypotonic CP
32. D/Ds of Mixed UMN & LMN Lesion

a) Recovery phase of TM
b) Spinal Tumor
c) Spinal TB (Potts Disease)
d) Spinal Aneurysm
33. Cyanosis & Clubbing

a) TOF
b) TGA with VSD
c) TA with VSD
d) Complex CHD
7
34. Cyanosis with PSM (LLSE)
a) TGA with VSD
b) TA with VSD
c) PA with VSD
d) Ebstein Anomaly
35. PSM @ LLSE without Cyanosis

a) VSD
b) AVSD
c) Pink TOF (in small child)
d) MR (in older child)
36. D/Ds of RHD

a) MR
b) VSD with CCF
c) CHD with Infective Endocarditis
37. D/Ds of TOF

a) TOF
b) Severe Pulmonary Stenosis
c) TGA with VSD & PS
d) TA with VSD & PS
e) PA with VSD
f) Complex CHD
38. D/Ds of Pink TOF

a) Pink TOF
b) PS
c) ASD
d) Infundibular Stenosis
e) Supracristal VSD
39. D/Ds of PDA

a) PDA
b) AP window
c) AV Fistula
d) VSD with AR
e) ASD with AR
f) MR with AR
40. ESM/LUSE
a) PS
b) ASD
c) AS
d) Supracristal VSD
8
41. D/Ds of ASD (ESM + Fixed Splitting)
a) ASD
b) AVSD
c) Partial APVD
d) PS
42. D/Ds of Large Tongue with Coarse Facial Features with Umbilical Hernia
a) Hypothyroidism
b) MPS
c) Beckwith Weidman Syndrome
43. Wheezing only (otherwise well child)

a) Bronchial Asthma
b) GERD
c) Vocal cord dysfunctions
d) Foreign body Aspiration (sudden distress)
44. Wheezy chest

a) Bronchial Asthma
b) Bronchopneumonia
c) Bronchiectasis
d) GERD
e) TB
f) Interstitial Lung disease
g) Bronchiolitis
e) Vocal Cord Dysfunctions
f) Foreign body Aspiration (without distress)
45. D/Ds of Lobar Pneumonia with signs of Consolidations

a) Lobar Pneumonia
b) Foreign body Aspiration (sudden distress)
c) TB
46. Bronchiectasis
a) Cystic Fibrosis
b) TB
c) Primary Ciliary Dyskinesia
d) Immunodeficiency
e) Pneumonia
f) Chronic Aspiration in CP patient
9
47. D/Ds of Edema
a) Nephrotic Syndrome
b) Malnutrition
c) Protein losing enteropathy
d) CLD … with stigmata
e) CCF … with other signs
48. D/Ds of Rickets

a) Nutritional Rickets
b) Hypophosphatemic Rickets
c) VDDR
d) Hypherphosphastasia
e) 2ndary Rickets … due to other diseases
 Wilson disease/CLD
 Lowe Disease
 Fanconi Syndrome / RTAs
 Hypoparathyroidism
 CKD
 IEMs
f) Metephysal dysplasia
g) MPS IV
10

Differential of Short Cases

Uploaded by

Copyright:

Available Formats

Differential of Short Cases

Uploaded by

Document Information

Original Title

Copyright

Available Formats

Share this document

Share or Embed Document

Sharing Options

Did you find this document useful?

Is this content inappropriate?

Copyright:

Available Formats

Differential of Short Cases

Uploaded by

Copyright:

Available Formats

DIFFERENTIAL FOR SHORT CASES IN PEDIATRICS

By Dr Muhammad Sajid Sabir … Edited by Dr Kalim Marwat

1. Jaundice +ve, Liver +ve, Spleen -ve

2. Jaundice –ve, Liver & Spleen (HSM) +ve,

3. Jaundice +ve, Liver & Spleen (HSM) +ve

4. Jaundice +ve, Spleen +ve, Anemia +/- ve, Liver –ve

5. LN +ve, Liver & Spleen (HSM) +ve

7. Anemia +ve, Liver & Spleen (HSM) +ve

10. Anemia only (HSM –ve)

12. D/Ds of Thalassemia All are transfusion-dependent anemias

13. D/Ds of HSP

15. Persistent Neonatal Jaundice(Direct)

18. D/Ds of Petechi

19. D/Ds of Bruises

20. D/Ds Bowed Legs

23. Very Painful Monoarthritis

24. Acidotic Breathing

II. Without Hydrocephalus

28. Paraplegia – Spastic

31. Quadriplegia … Flaccid

32. D/Ds of Mixed UMN & LMN Lesion

33. Cyanosis & Clubbing

35. PSM @ LLSE without Cyanosis

36. D/Ds of RHD

37. D/Ds of TOF

38. D/Ds of Pink TOF

39. D/Ds of PDA

43. Wheezing only (otherwise well child)

44. Wheezy chest

45. D/Ds of Lobar Pneumonia with signs of Consolidations

48. D/Ds of Rickets

You might also like

Pfad - The Proxy pFad of © 2024 Garber Painting. All rights reserved.