10 Q For Practice

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Subject : Pathology

1. A 60 year old male with complaints of hematuria and mild facial


puffiness with occasional hemoptysis. The DIF picture of the patient is
given below. Which of the following is not true about the given
condition?

a. Antibody to alpha 3 chain of type 4 collagen part of non-collagenous


domain is responsible
b. Strong association with HLA DR B1
c. Crescents are seen in >50% of the glomeruli
d. Dense depositions below podocytes are seen in electron microscopy
2. 24/f presented with painless left sided breast lump for last 2 months.
Local examination revealed soft mobile, non tender mass. Excision
biopsy was done & histopathological image is shown below as shown
below. What is your diagnosis?

a. Phyllodes tumor
b. Intraductal ca breast
c. Fibroadenoma
d. Ductal ca in situ
3. A 45 year old patient presented with features of hypothyroidism
from 2-3 years, the histopathology is shown below. Based on
histological features what is your diagnosis

a. Hashimoto’s thyroiditis
b. Granulomatous thyroiditis
c. Papillary carcinoma
d. Riders thyroiditis
4. A 45 year old patient presented with hypertension, excessive
sweating and palpitations. Patient is chronic hypertensive and CT scan
shows lession in adrenal. The histopathology of the same is shown
below, identify the lesion

a. Pheochromocytoma
b. Neuroblastoma
c. Carcinoids
d. Ganglioma
5. A 20- year-old presented to the clinic with history of malabsorption,
diarrhea and poor appetite, Vomiting, poor appetite. Duodenal Biopsy
of the patient showed crypt hyperplasia, villi atrophy, CD8+ Cells in
lamina propria. Your most probable diagnosis is.

a. Environmental enteropathy
b. Celiac disease
c. Whipple’s disease
d. Chronic Pancreatitis
6. 42-year-old man who presented with vague abdominal complaints,
which on evaluation as found to have multiple colorectal polyps and
underwent a prophylactic proctocolectomy with end continent
ileostomy. Two of his children were evaluated and found to have
multiple colorectal polyps on colonoscopy and have been advised
regular follow up annually. True/false?

1. Autosomal recessive
2. Adenomatous polyp are seen
3. More than 100 polyps is confirmatory
4. Extraintestinal manifestations are rare
a. 1-True, 2-true,3-false,4-false
b. 1-false, 2-false,3-true,4-false
c. 1-false, 2-true, 3-true,4-false
d. 1-True, 2-true,3-true,4-false
7. All of the following statement are true regarding histological features
of rheumatic heart disease except
a. Diffuse inflammation and Aschoff bodies may be
found in any of the three layers of the heart
b. Subendocardial lessions, McCallum plaques, usually in the right
atrium
c. Leaflet thickening, commissural fusion
d. Shortening, and thickening and fusion of the tendinous cords
8. Autopsy of a person who died of severe respiratory distress following
COVID 19 shows the following. Which of the given statement is not true
about the condition?

a. Endothelial cell activation is an important early event


b. Alveolar hyaline membranes consists of fibrin-rich edema fluid
mixed with the cytoplasmic and lipid remnants of necrotic epithelial
cells.
c. Edema, scattered neutrophils and macrophages, and epithelial
necrosis are also present
d. Neutrophils adhere interstitium and the alveoli and migrate to
endothelium
9. A 6 year old child presents with pallor that required two blood
transfusions previously. He has now developed fever and petechial
hemorrhages. His hemoglobin is 9 g/dL, platelet count is 20,000/mm3
and TLC is 60,000/mm3. Flow cytometry reveals the cells to be CD10
+ve, MPO +ve, CD19 +ve, CD33 –ve, CD117 +ve, and CD3 –ve. Which of
the following is the most likely diagnosis?
a. ALL
b. AML
c. Mixed phenotypic leukemia
d. Undifferentiated leukemia
10. A 15-year-old female visited the OBG clinic with complaints of heavy and long
menstrual bleeding with blood clots in her menstrual flow which she thought were
abnormal. On taking further history she revealed that she had to use double sanitary
protection and change it very often. On asking about her past history she revealed that
there had been episode of easy bruising and nosebleeds as a child. You order for blood
tests and the following results come back:
Bleeding time- Prolonged.
APTT- Increased
PT- Normal
Tourniquet test- Positive.
Clotting time (CT)- Prolonged.
What is the most likely diagnosis?

A. Immune thrombocytopenic purpura


B. Von Willebrand disease
C. Haemophilia A
D. Haemophilia B

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