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STEREOCHEMISTRY
1. Define stereochemistry and explain its significance in organic chemistry.
2. What are enantiomers? Give an example of a pair of enantiomers. 3. Explain the concept of chirality with examples. 4. Describe the di erence between enantiomers and diastereomers. Provide examples. 5. What is optical activity? How do you measure it in a laboratory? 6. Explain the Cahn-Ingold-Prelog priority rules for assigning R and S configurations. 7. Draw and assign the R/S configuration for 2-butanol. 8. What is a meso compound? How does it di er from other stereoisomers? 9. Di erentiate between geometrical (cis-trans) isomerism and optical isomerism. 10. Describe the significance of the plane of symmetry in determining molecular chirality. 11. What are racemic mixtures, and how can they be resolved into pure enantiomers?
12. How do conformational isomers di er from configurational isomers?
13. Discuss the stereochemical outcome of a nucleophilic substitution reaction (SN1 vs. SN2).