Skeletal System
Skeletal System
Structure
– Made of cartilage tissue (cells = chondrocytes)
– Contains large amounts of water (which accounts for its resilience=
ability to spring back to its original shape after being compressed)
– No nerves fibers
– Surrounded by a fibrous perichondrium (contain blood vessels) that
resists expansion
Types (3) and Location
1. Hyaline cartilages
– Network of collagenous fibers, translucent (glassy)
– Provide support with flexibility and resilience
– The most abundant skeletal cartilages
– Form most of embryonic skeleton (before bone is formed), articular
cartilages, costal cartilages, respiratory cartilages (laryngeal cartilages,
tracheal and bronchial cartilages), and nasal cartilages
2. Elastic Cartilages
– Contain more elastic fibers, in addition to collagenic fibers
– Provide more flexible than hyaline cartilage and lightweight support
– Form the external ear and epiglottis
Epiglottis
Thyroid Larynx
Cartilage in Cartilages in cartilage
external ear nose Cricoid Trachea
Articular Lung
cartilage
Cartilage
of a joint
Cartilage in
Costal
Intervertebral
cartilage
disc
Figure 6.1
3. Fibrocartilages
– Contain thick collagen fibers
– Provide support and protection, highly compressible and has great
tensile strength
– Form the intervertebral disc, pubic symphysis, disc of knee joint
(menisci)
Growth of Cartilage
– Cartilage grows from within (interstitial growth = growth from inside),
and by addition of new cartilage tissue at the periphery (appositional
growth)
Classification of Bones
– Classified on the basis of their shape
1. Long bones
– Length greater than width
– Composed of a diaphysis (shaft) and two epiphyses (ends)
– All limbs bones are long bones except patella, carpals & tarsals
– e.g. humerus, radius, ulna, femur, phalanges, etc
2. Short bones
– Cube shaped
– e.g. carpals, tarsals, patella (sesamoid bone = form in a tendon)
Figure 6.2
3. Flat bones
– Thin, flattened, a bit curved
– e.g. ribs, sternum, skull bones, scapulae
4. Irregular bones
– Complicated shapes
– e.g., verterbrae, facial bones, hip bones
Functions of Bones
1. Support
– Provide the rigid framework that support the body
2. Protection
– Protect vulnerable internal organs such as brain, heart, lungs, etc.
3. Movement
– Providing anchoring points for muscles and by acting as levers at the
joints
4. Mineral storage
– Serves as a reservoir for minerals (most important - calcium and
phosphate)
5. Blood cell formation (hematopoiesis)
– Occurs within the red marrow cavities of certain bones
Bone Structure
– Bones are organs because they contain various types of tissues:
• Bone (osseous) tissue
• Nervous tissue in their nerves
• Cartilage in their articular cartilages
• Fibrous connective tissue lining the cavity
• Smooth muscle tissue & epithelial tissue in the blood vessels
Table 6.1
Table 6.1
Table 6.1
Structure of a Long Bone
Diaphysis
– Shaft
– Compact bone surrounds central medullary cavity (marrow cavity)
contains fat (yellow marrow), called the yellow bone marrow cavity
Articular
cartilage
Compact bone
Proximal
epiphysis Spongy bone
Epiphyseal
line
Periosteum
Compact bone
Medullary
cavity (lined (b)
by endosteum)
Diaphysis
Distal
epiphysis
(a)
Figure 6.3a-b
Endosteum
Yellow
bone marrow
Compact bone
Periosteum
Perforating
(Sharpey’s) fibers
Nutrient
arteries
(c)
Figure 6.3c
2. Epiphyses
– Bone ends
– Wider than the shaft
– Spongy epiphyses filled with red bone marrow
– Joint surface covered with articular (hyaline) cartilage (cushions the
opposing bone ends during joints movement and absorbs stress)
– Between epiphysis and diaphysis is an epiphyseal line (adult), a
remnant of the epiphyseal plate (childhood); this region sometimes
called the metaphysis
3. Membranes
– Bone covered with:
a. Periosteum (external bone surface)
• Double layered membrane (outer fibrous layer = dense irregular
connective tissue, and inner osteogenic layer, consists of
osteoblasts = bone-forming cells and osteoclasts = bone-
destroying cells)
• Cover the diaphysis
• Supplied with nerve fibers, lymphatic vessel, blood vessels
(enter via a nutrient foramen)
• Provide insertion or anchoring points for ligaments and tendons
(a) Osteogenic cell (b) Osteoblast
Figure 6.4a-b
(c) Osteocyte (d) Osteoclast
Figure 6.4c-d
b. Endosteum (internal bone surface)
• Delicate connective tissue
• Lines the inner bone cavities (covers the trabeculae of spongy
bone in marrow cavities)
• Contains both osteoblasts (bone forming cells) and osteoclasts
(bone destroying cells)
Structure of Short, Irregular and Flat Bones
– Consist of:
1. Periosteum
2. Endosteum
– Without diaphysis or epiphysis
– Contain bone marrow (between their trabeculae), but no marrow
cavity
– In flat bone, spongy bone called diploe
Spongy bone
(diploë)
Compact
bone
Trabeculae
Figure 6.5
Location of Hematopoietic Tissue in Bones
– In adults, red marrow found within the diploe of flat bones and within
the epiphyses of long bones (trabecular cavities of spongy bone)
– In infants red marrow is also found in the medullary cavity
Microscopic Structure of Bone
Compact bone
– Form outer shell of a bone
– Very hard and dense
– The structural unit of compact bone is called osteon or Haversian
system
– The osteon consists of a central canal surrounded by concentric
lamellae of bone matrix
– Osteocytes, embedded in lacunae, are connected to each other & the
central canal by canaliculi
Artery with
capillaries
Structures
in the Vein
central Nerve fiber
canal
Lamellae
Collagen
fibers
run in
different
directions
Twisting
force
Figure 6.6
Compact Spongy bone
bone
Central Perforating
(Haversian) canal (Volkmann’s) canal
Endosteum lining bony canals
Osteon and covering trabeculae
(Haversian system)
Circumferential
lamellae
(a)
Perforating (Sharpey’s) fibers
Lamellae Periosteal blood vessel
Periosteum
Nerve
Vein
Artery Lamellae
Central Lacuna (with
Canaliculi
canal osteocyte)
Osteocyte Lacunae
in a lacuna
(b) (c) Interstitial lamellae
Figure 6.7a-c
Spongy (Cancellous) bone
– Consist of trabeculae filled with red or yellow marrow
– Withstand stress and support shifts in weight
1. Intramembranous Ossification
– Forms the clavicles and most skull bones
– Bones develop from mesenchymal cells
– The ground substance of the bone matrix is deposited between
collagen fibers within the fibrous membrane to form spongy bone
– Bone develops from a fibrous membrane called a membrane bone
– Eventually, compact bone plates enclose the diploe
Five steps can summarize intramembranous ossification:
Osteoid
Osteocyte
Newly calcified
bone matrix
Figure 6.8, (2 of 4)
Mesenchyme
condensing
to form the
periosteum
Trabeculae of
woven bone
Blood vessel
Osteoblast
Plate of
compact bone
Diploë (spongy
bone) cavities
contain red
marrow
Articular cartilage
Cartilage
grows here.
Epiphyseal plate
Cartilage
is replaced Bone is
by bone here. resorbed here.
Cartilage
grows here. Bone is added
by appositional
Cartilage growth here.
is replaced
by bone here. Bone is
resorbed here.
Figure 6.11
Bone Homeostasis
Bone Remodeling
– New bone is continually doposited and resorbed (removal) in respond to
hormonal and mechanical stimuli
– Continuous recycling of bone (remodeling units) occurs when:
• Osteoblast produce new matrix
• Osteoclast destroy old matrix
– Control of remodeling (hormonal mechanism)
Bone Repair
– Bones are susceptible to fractures or breaks
– Fractures = break in bone, resulting from twists or smashes of bones
– Bones thinning and weaken (old age)
Healing (Repair)
1. Axial skeleton
– 80 bones
– Forms the longitudinal axis of the body
– Skull (cranial and facial bones), vertebral column and bony thorax
– Provides support and protection (by enclosed)
2. Appendicular skeleton
– 126 bones
– Pectoral (shoulder) girdle, pelvis girdle, upper and lower limbs
– Allows mobility for manipulation and locomotion
Cranium
Skull
Facial bones
Clavicle
Thoracic cage Scapula
(ribs and Sternum
sternum) Rib
Humerus
Vertebral Vertebra
Radius
column Ulna
Sacrum Carpals
Phalanges
Metacarpals
Femur
Patella
Tibia
Fibula
Tarsals
Metatarsals
(a) Anterior view Phalanges
Figure 7.1a
Axial Skeleton
The Skull
– 22 bones
– Cranial bones/ cranium (8) protect the brains
• Frontal (1), occipital (1), ethmoid (1), sphenoid (1), parietal (2) and
temporal (2)
– Facial bones (14) provides openings for the respiratory and digestive
passage, and attachment points for facial muscles
• Mandible (1), vomer (1), maxillae (2), zygomatics (2), palatines (2),
nasal (2), lacrimals (2) and inferior nasal conchae (2)
• Mandible = largest and strongest bone of the face
Bones of cranium (cranial vault)
Coronal
suture
Squamous
suture
Lambdoid Facial
suture bones
Squamous
suture Nasal bone
Occipital
bone Zygomatic
Zygomatic bone
process
Maxilla
Occipitomastoid
suture
External acoustic
meatus
Mastoid process Alveolar
Styloid process margins
Mandibular condyle Mandible
Mandibular notch Mental foramen
Mandibular ramus
Mandibular angle Coronoid process
Figure 7.5a
Sagittal suture
Parietal
bone
Sutural
bone
Lambdoid
suture
Occipital bone
External
occipital Mastoid
protuberance process
Inferior
Occipitomastoid nuchal
External Occipital
suture line
occipital condyle
(b) Posterior view crest
Figure 7.4b
– All bones of the adult skull are joined by immovable sutures except for the
temporomandibular joints
– Orbits and nasal cavity: complicated bony regions formed of several bones
– Paranasal sinuses: occur in the frontal, ethmoid, sphenoid and maxillary
bones
– Hyoid bone: not really a skull bone, is supported in the neck by ligaments,
serves as an attachment point for tongue and neck muscles
Frontal sinus
Superior, middle, and Superior
inferior meatus nasal concha Ethmoid
Middle
bone
nasal concha
Inferior nasal
concha
Nasal bone
Figure 7.15
Greater horn
Lesser horn
Body
Figure 7.12
2. The Vertebral Column/ Spine
– 26 bones
– Vertebrae (24), sacrum (1) and coccyx (1)
• 24 movable vertebrae; 7 cervical (C1-C7), 12 thoracic (T1- T12), and 5
lumbar (L1-L5)
o C1= atlas, C2= axis (joint allows to rotate head side to side to
indicate “no”
• 1 sacrum (5 fused vertebrae)
• 1 coccyx (4 fused vertebrae)
– Separated by fibrocartilage intervertebral disc acts as shock absorbers
and provide flexibility
– The S-shaped to allow for upright posture
C1
Cervical curvature
(concave)
7 vertebrae, C1–C7
Spinous
process
Transverse
processes
Thoracic
curvature
(convex)
12 vertebrae,
T1–T12
Intervertebral
discs
Intervertebral
foramen
Lumbar curvature
(concave)
5 vertebrae, L1–L5
Sacral curvature
(convex)
5 fused vertebrae
sacrum
Coccyx
4 fused vertebrae
Anterior view Right lateral view
Figure 7.16
Dens of axis
Transverse ligament
of atlas
C1 (atlas)
C2 (axis)
C3
Inferior articular
process
Bifid spinous
process
Transverse processes
C7 (vertebra
prominens)
Ala
Body of
first
sacral
vertebra
Transverse
ridges (sites
of vertebral
fusion)
Anterior
sacral
Apex foramina
Coccyx
Figure 7.21a
– Primary spinal curvatures (thoracic and sacral) present at birth
– Secondary spinal curvatures (cervical and lumbar) develop after birth
– Curvatures increase spine flexibility
C1
Cervical curvature
(concave)
7 vertebrae, C1–C7
Spinous
process
Transverse
processes
Thoracic
curvature
(convex)
12 vertebrae,
T1–T12
Intervertebral
discs
Intervertebral
foramen
Lumbar curvature
(concave)
5 vertebrae, L1–L5
Sacral curvature
(convex)
5 fused vertebrae
sacrum
Coccyx
4 fused vertebrae
Anterior view Right lateral view
Figure 7.16
3. The Bony Thorax or Thoracic Cage
– Sternum (1) and ribs (12 pairs) protect the organs of the thoracic cavity
– Sternum (breastbone) consists of fused manubrium, body and xiphoid
process
– All ribs attach posteriorly to thoracic vertebrae
– Anteriorly, the first 7 rib pairs are called true ribs attach directly to
sternum
– Last 5 pairs are called false ribs (rib pairs 8, 9 & 10 attach indirectly to
sternum and rib pairs 11 and 12 are floating ribs)
Jugular notch
Clavicular notch
Manubrium
Sternal angle
Body
Sternum
True Xiphisternal
ribs joint
(1–7) Xiphoid
process
False
Intercostal spaces
ribs
(8–12) Costal cartilage
Costal margin
L1
Vertebra
Floating ribs (11, 12)
(a) Skeleton of the thoracic cage, anterior view
Figure 7.22a
Appendicular Skeleton
Scapula
Figure 7.24a
2. The Upper Limb
– Each upper limb consists of 30 bones and is specialized for mobility
– Arm (humerus), forarm (radius and ulna), hand (carpals, metacarpals
and phalanges)
Greater Head of
tubercle humerus
Lesser Anatomical
tubercle neck
Inter-
tubercular
sulcus
Deltoid
tuberosity
Lateral
supracondylar Coronoid
ridge fossa
Radial Medial
fossa epicondyle
Capitulum Trochlea
(a) Anterior view
Figure 7.26a
Radial
Olecranon
notch of
process
the ulna
Trochlear
Head notch
Coronoid Head of
Neck
process radius
Radial Neck of
Proximal
tuberosity radius
radioulnar
joint
Interosseous
membrane
Ulna
Radius
Metacarpals
• Head
• Shaft
Sesamoid • Base
bones Carpals
Carpals Carpals
• Hamate • Trapezium
• Trapezium • Trapezoid
• Trapezoid • Capitate
• Pisiform • Scaphoid
• Scaphoid
• Triquetrum
Radius • Lunate
Ulna Radius
(a) Anterior view of left hand (b) Posterior view of left hand
Figure 7.28a-b
3. The Pelvic (Hip) Girdle
– Formed by two coxal/hip bones
– Together with the sacrum, the hip bones form the basinlike bony pelvis
– Each hip bone is result of fusion of the ilium, ischium and pubis/pubic
bones
– V-shape pubic bones articulate anteriorly at the pubic symphysis
(fibrocartilage disc) forming an arch called pubic arch (helps to
differentiate male and female pelves)
– Female pelvis is light and broader; inlet is larger and more circular,
which reflects the childbearing function (birth canal)
Base of sacrum
Iliac crest
Sacroiliac
joint
Iliac fossa Anterior
superior
iliac spine
Sacral
Coxal promontory
bone Anterior inferior
llium
(os coxae iliac spine
or hip Pubic Sacrum
Pelvic brim
bone) bone Coccyx
Acetabulum
Pubic tubercle
Ischium
Pubic crest
Pubic symphysis
Pubic arch
Figure 7.29
Anterior gluteal Ilium
line Ala
Posterior
gluteal line Iliac crest
Posterior Anterior
superior superior
iIiac spine iliac spine
Posterior inferior Inferior
iliac spine gluteal line
Greater sciatic
Anterior inferior
notch
Ischial body iliac spine
Ischial spine Acetabulum
Lesser sciatic Pubic body
notch Pubis
Ischium
Ischial Inferior ramus
tuberosity of pubis
Ischial ramus Obturator foramen
(a) Lateral view, right hip bone
Figure 7.30a
4. The Lower Limb
– Each lower limb consists of the thigh (femur), leg (tibia and fibula) and
foot (tarsals, metatarsals, and phalanges), and is specialized for weight
bearing and locomotion
– Foot supported by 3 arches (lateral, medial and transverse) that
distribute body weight to the heel and the ball of the foot
Neck Fovea Greater
capitis trochanter
Head
Inter-
Lesser trochanter trochanteric
Intertrochanteric crest
line
Gluteal tuberosity
Figure 7.31
Articular surface Articular surface of
of medial condyle lateral condyle
Interosseous
membrane
Tibia Fibula
Articular surface
Medial malleolus
Lateral malleolus
(b) Posterior view
Figure 7.32b
Phalanges
Distal
Middle
Proximal
1 2 3 4 5
Medial Metatarsals
cuneiform
Intermediate Lateral
cuneiform cuneiform
Navicular Cuboid Tarsals
Talus
Trochlea
of talus
Calcaneus
(a) Superior view
Figure 7.33a
Talus Facet for
medial
Intermediate Navicular malleolus
cuneiform Sustentac-
ulum tali
First metatarsal (talar shelf)
Medial Calcaneus
cuneiform
Calcaneal
(b) Medial view tuberosity
Figure 7.33b
Medial longitudinal
arch
Transverse arch
Lateral
longitudinal arch
Figure 7.34a
ARTICULATIONS (JOINTS)
– Sites where bones meet
– Functions are to hold bones together and to allow movement of the skeleton
– 3 functional categories:
1. Synarthroses (immovable)
2. Amphiarthroses (slightly movable)
3. Diarthroses (freely movable)
– Classified structurally as fibrous, cartilaginous, or synovial
1. Fibrous Joints
– Fibrous connective tissue unites the bones
– No joint cavity
– Usually synarthroses (immovable) or synarthrotic
– Types of fibrous joints:
a. Sutures (skull)
b. Syndesmoses (tibia and fibula)
c. Gomphoses (tooth)
(a) Suture
Joint held together with very short,
interconnecting fibers, and bone edges
interlock. Found only in the skull.
Suture
line
Dense
fibrous
connective
tissue
Figure 8.1a
(b) Syndesmosis
Fibula
Tibia
Ligament
Figure 8.1b
(c) Gomphosis
Socket of
alveolar
process
Root of
tooth
Periodontal
ligament
Figure 8.1c
2. Cartilaginous Joints
– Bones are unites by a plate of hyaline cartilage or a softer
fibrocartilaginous disc
– No joint cavity
– Usually amphiarthroses (slightly movable) or amphiarthrotic
– Types of cartilaginous joints:
a. Synchondroses: synarthrotic (epiphyseal plate and costal cartilage)
b. Symphyses: amphiarthrotic (pubic symphysis)
(a) Synchondroses
Bones united by hyaline cartilage
Sternum
(manubrium)
Epiphyseal
plate (temporary Joint between
hyaline cartilage first rib and
joint) sternum
(immovable)
Figure 8.2a
(b) Symphyses
Bones united by fibrocartilage
Body of vertebra
Fibrocartilaginous
intervertebral
disc
Hyaline cartilage
Pubic symphysis
Figure 8.2b
3. Synovial Joints
– Bones move easily on each other
– Ends of the bones are plated with a smooth articular cartilage
– Enclosed within joint cavity by a fibrous articular capsule and lubricate
with synovial fluid
– Usually diarthroses (freely movable joint) or diarthrotic
Ligament
Joint cavity
(contains
synovial fluid)
Articular (hyaline)
cartilage
Fibrous
capsule
Articular
Synovial capsule
membrane
Periosteum
Figure 8.3
Table 8.2 (1 of 4)
Table 8.2 (2 of 4)
Table 8.2 (3 of 4)
Table 8.2 (4 of 4)
Structure of Synovial Joints
1. Articular cartilage
– Hyaline cartilage covers the surfaces
– Absorb compression
2. Joint/Synovial cavity
– Joint cavity contains synovial fluid for lubrication
3. Articular capsule
– 2 layered:
a. Fibrous capsule
b. Synovial membrane
4. Synovial fluid
– Occupies space within the joint capsule
– Reduce reduction between cartilages
5. Reinforcing ligaments
– Thicken parts of fibrous capsule
– Supplied with nerve endings and blood vessels
Ligament
Joint cavity
(contains
synovial fluid)
Articular (hyaline)
cartilage
Fibrous
capsule
Articular
Synovial capsule
membrane
Periosteum
Figure 8.3
Movements Allowed by Synovial Joints
– Movements can occur when muscle contract across joints:
• Gliding movements • Medial rotation & lateral rotation
• Flexion • Supination & pronation
• Extension & hyperextension • Inversion & eversion
• Dorsiflexion & plantar flexion • Protraction & retraction
of the foot
• Elevation & depression
• Abduction
• Opposition
• Adduction
• Circumduction
Gliding
Flexion
Hyperextension Flexion
Flexion
Extension
Adduction Circumduction
Lateral
rotation
Medial
rotation
Dorsiflexion
Plantar flexion
Plantar flexion
(f) Opposition
Figure 8.6f
Types of Synovial Joints
– Differ in range of motion; nonaxial (gliding), uniaxial (in one plane), biaxial
(in two planes), or multiaxial (in all three planes) 22 bones
– Types of synovial joints:
1. Plane (gliding) joints: intercarpals and intertarsals joints
1. Hinge joint: elbow and knee joints, and interphalangeal joints
2. Pivot joint: atlas and axis joint,and proximal radioulnar joint
3. Condyloid joint: radiocarpal/wrist joints and knuckle joints
4. Saddle joint: carpometacarpal joints of the thumb
5. Ball and socket joint: shoulder joints and hip joints
f
Nonaxial
Uniaxial
Biaxial
Multiaxial
c b
a Plane joint (intercarpal joint)
a
e
d
Figure 8.7a
f
Nonaxial
Uniaxial
Biaxial
Multiaxial
c b
b Hinge joint (elbow joint)
a
e
d
Figure 8.7b
f
Nonaxial
Uniaxial
Biaxial
Multiaxial
c b
a
e
d
Figure 8.7c
f
Nonaxial
Uniaxial
Biaxial
Multiaxial
c b
d Condyloid joint
(metacarpophalangeal joint)
a
e
d
Figure 8.7d
f
Nonaxial
Uniaxial
Biaxial
Multiaxial
c b
e Saddle joint (carpometacarpal joint
of thumb)
a
e
d
Figure 8.7e
f
Nonaxial
Uniaxial
Biaxial
Multiaxial
c b
f Ball-and-socket joint (shoulder joint)
a
e
d
Figure 8.7f