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Pharmaceutical Intermediates Market (By Product: Chemical

Intermediates, Bulk Drug Intermediates, Custom Intermediates; By
Application: Analgesics, Ant-inflammatory Drug, Cardiovascular
Drugs, Anti-Diabetic Drugs, Anti-Cancer Drugs, Others; End User:
Biotech & Pharma Companies, Research Laboratory, CMO/CRO) -
Global Industry Analysis, Size, Share, Growth, Trends, Revenue,
Regional Outlook and Forecast 2024-2033

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Research Methodology

Pharmaceutical Intermediates Market Size and Growth 2024

to 2033
The global pharmaceutical intermediates market size was estimated at around
USD 33.63 billion in 2023 and it is projected to hit around USD 54.78 billion by
2033, growing at a CAGR of 5% from 2024 to 2033. The pharmaceutical
intermediates market plays a crucial role in the global pharmaceutical industry
by providing essential substances for the synthesis of active pharmaceutical
ingredients (APIs). These intermediates are compounds used during the
production process of APIs, influencing the efficacy, safety, and cost-
effectiveness of pharmaceutical products.

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Key Pointers
North America dominated the global pharmaceutical intermediates market
with the largest market share of 34% in 2023.

By Product, the bulk drug intermediates segment captured the maximum

market share in 2023.

By Application, the analgesics segment generated the maximum market

share of 31% in 2023.

By End User, the CROs/CMOs segment held the largest revenue share in
2023.

Why pharmaceutical intermediates?

Pharmaceutical intermediates are drugs used as raw materials in the
production of bulk drugs. Moreover, they are widely used to refer to a material
created during the synthesis of an active pharmaceutical ingredient (API)
before the processing of becoming an API. Pharmaceutical intermediates are
usually formed using high-grade raw materials. These intermediates are widely
used in the pharmaceutical and cosmetic industries. The rising demand in
these industries is expanding the global pharmaceutical intermediates market.
Pharmaceutical intermediates are popularly used for research and
development in the pharmaceutical industry. The pharmaceutical intermediates
are increasingly being produced using raw materials such as coal tar or
petroleum to manufacture pesticides, pharmaceuticals, resins, additives,
plasticizers, etc. However, several intermediates can be produced in organic
synthesis, and be used in creating various drugs and products.

What are the Growth Factors of Pharmaceutical

Intermediates Market?

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The growth of the pharmaceutical intermediates market is driven by an

increasing global prevalence of chronic diseases, coupled with an aging
population, has significantly heightened the demand for pharmaceuticals,
thereby boosting the need for intermediates. Advancements in chemical
synthesis and biotechnology also contribute to market growth by improving the
efficiency and yield of pharmaceutical intermediate production. Additionally, the
rise in generic drug production, spurred by patent expirations of major drugs,
has created a robust demand for intermediates. Moreover, the expansion of
pharmaceutical research and development activities, aimed at discovering new
treatments and therapies, further stimulates the market. Together, these factors
underscore a dynamic environment for the pharmaceutical intermediates
market, paving the way for sustained growth.

What are the Trends in Pharmaceutical Intermediates

Market?
Growth in Specialty Pharmaceuticals: The rise in specialty
pharmaceuticals, including biologics and personalized medicines, is driving
the demand for specialized intermediates. These complex drugs often
require unique and high-purity intermediates, prompting innovation and
expansion in this segment.

Increasing Focus on Green Chemistry: There is a growing emphasis on

green chemistry principles within the pharmaceutical intermediates sector.
Companies are adopting environmentally friendly practices to reduce waste,
energy consumption, and the use of hazardous chemicals, aligning with
global sustainability goals.

Technological Advancements in Manufacturing: Advances in

manufacturing technologies, such as continuous flow chemistry and
process optimization, are enhancing the efficiency and scalability of
pharmaceutical intermediate production. These innovations contribute to
reduced production costs and improved product quality.

Expansion of Generic Drug Production: The pharmaceutical industry’s

shift towards generic drug production is driving up the demand for
intermediates. As patents on major drugs expire, generic manufacturers
require a steady supply of intermediates to produce cost-effective
alternatives.

What are the Key Challenges Faced by Pharmaceutical

Intermediates Market?
Stringent Regulatory Requirements: Compliance with strict regulatory
standards for quality, safety, and environmental impact presents a
significant challenge. Adhering to regulations set by agencies like the FDA
and EMA can be complex and costly for manufacturers.

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High Production Costs: The production of pharmaceutical intermediates

involves high costs due to complex chemical processes, raw material
expenses, and stringent quality controls. These high costs can impact profit
margins and market competitiveness.

Supply Chain Vulnerabilities: Disruptions in the supply chain, such as

geopolitical tensions, natural disasters, or trade restrictions, can affect the
availability and cost of raw materials and intermediates, leading to potential
production delays and increased costs.
Intellectual Property Issues: Protecting intellectual property (IP) related to
the synthesis and manufacturing of intermediates is crucial. Patent disputes
and IP theft can lead to legal challenges and impact market positioning.

Which Region Dominates the Pharmaceutical Intermediates

Market?
In 2023, North America led the global market with the largest market
share of 34% and is projected to maintain its leading position throughout
the forecast period. This dominance is attributed to the region's robust
presence of pharmaceutical companies, research centers, and laboratories,
alongside the rapidly expanding Contract Manufacturing Organizations (CMOs)
and Contract Research Organizations (CROs) in the US and Canada.
Additionally, significant investments by both government and private sectors
aimed at advancing the biopharmaceutical industry are expected to further
support North America's market leadership.

What is the Contribution of North America to Pharmaceutical

Intermediates Market?

Attribute North America

Market Value USD 11.43 Billion

Growth Rate 5% CAGR

Projected Value USD 18.62 Billion

In contrast, the Asia Pacific region is anticipated to present significant growth

opportunities during the forecast period. Investments by market players to
establish manufacturing facilities in countries such as China, India, Japan,
South Korea, and Singapore—driven by the availability of low-cost production
factors and favorable government policies—are expected to fuel the growth of
the pharmaceutical intermediates market in this region.

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Product Insights
The bulk drug intermediates segment represented the largest revenue
share in 2023. These intermediates are crucial for the production of active
pharmaceutical ingredients (APIs), which are essential for the therapeutic
efficacy of drugs. Government initiatives aimed at promoting and developing
bulk drug parks, such as the Department of Pharmaceuticals' focus on 56 APIs
under the Make-in-India initiative, are likely to drive the growth of this segment.

Conversely, the custom intermediates segment is projected to be the fastest-

growing. Custom drug intermediates involve the tailored synthesis of specific
molecules to achieve targeted therapeutic effects. This segment is gaining
traction as demand for customized solutions increases.

Application Insights
In terms of application, the analgesics segment accounted for
approximately 31% of the global pharmaceutical intermediates market in
2023 and is expected to maintain its dominance. Analgesics are widely used
for pain relief, and the growing prevalence of chronic conditions such as
arthritis, cancer, and cardiovascular diseases is driving the demand in this
segment.

On the other hand, the anti-cancer drugs segment is anticipated to experience

rapid growth. This surge is due to the increasing global incidence of cancer.
According to the International Agency for Research on Cancer, there were
approximately 19.3 million new cancer cases and 10 million cancer deaths
worldwide in 2020, highlighting the need for continued growth in this segment.

End User Insights

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The CROs/CMOs segment led the pharmaceutical intermediates market

in 2023 in terms of revenue and is expected to maintain its leading
position. The growing presence and expansion of Contract Manufacturing
Organizations and Contract Research Organizations have significantly
increased the demand for pharmaceutical intermediates for drug production
and research purposes.

In contrast, research laboratories are expected to see rapid growth during the
forecast period. Increased private investment in pharmaceutical research for
new drug development is likely to drive the expansion of this segment.

Who are the Top Manufactures in Pharmaceutical

Intermediates Market?
Aceto Corporation

BASF SE

Chiracon GmbH

Yin-sheng Bio-tech Co. Ltd.

Dishman Group

Green Vision Life Sciences

Midas Pharma GmbH

Sanofi SAIS

Vertellus Holdings LLC.

Lonza Group

Pharmaceutical Intermediates Market Segmentation:

By Product

Chemical Intermediates
Bulk Drug Intermediates

Custom Intermediates

By Application

Analgesics
Ant-inflammatory Drug

Cardiovascular Drugs
Anti-Diabetic Drugs

Anti-Cancer Drugs
Others

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By End User

Biotech & Pharma Companies

Research Laboratory

CMO/CRO

By Region

North America

Europe

Asia Pacific

Rest of the World

Frequently Asked Questions

What is the current size of pharmaceutical intermediates market?

What is the CAGR of pharmaceutical intermediates market?

Which region has accounted for the largest pharmaceutical intermediates

market share?

Which are the leading companies in the pharmaceutical intermediates

market?

Report Details

Report Code: 38525

Category: Healthcare

No. of Pages: 150+

Format: PDF/PPT/Excel

Published: September 2024

Historical Year: 2021-2022

Base Year: 2023

Estimated Year: 2024-2033

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