DPP - Daily Practice Problems

Chapter-wise Sheets
Date : Start Time : End Time :

CB22
SYLLABUS : Chemical Co-ordination and Integration

Max. Marks : 180 Marking Scheme : + 4 for correct & (–1) for incorrect Time : 60 min.

INSTRUCTIONS : This Daily Practice Problem Sheet contains 45 MCQs. For each question only one option is correct.
Darken the correct circle/ bubble in the Response Grid provided on each page.

1. Which hormone possesses anti-insulin effect? (a) electrophoresis

(a) Cortisol (b) Calcitonin (b) electroencephalogram
(c) Oxytocin (d) Aldosterone (c) fractionation
2. Which of the following is both exocrine and endocrine gland ? (d) radioimmunoassay
(a) Liver (b) Pancreas 6. Testosterone is produced by
(c) Thyroid (d) Adrenal (a) sertoli cells (b) leydig’s cells
3. Chemically hormones are (c) oxyntic cells (d) pituitary gland
(a) biogenic amines only 7. Which one of the following pairs correctly matches a
(b) proteins, steroids and biogenic amines hormone with a disease resulting from its deficiency?
(c) proteins only (a) Luteinizing - Failure of ovulation
(d) steroids only (b) Insulin - Diabetes insipidus
4. The blood calcium level is lowered by the deficiency of (c) Thyroxine - Tetany
(a) parathormone (d) Parathyroid - Diabetes mellitus
(b) thyroxine 8. Which one of the following is not a second messenger in
(c) both calcitonin and parathormone hormone action ?
(d) calcitonin (a) Calcium (b) Sodium
5. The technique used for estimation of minute amounts of (c) cAMP (d) cGMP
hormones and drugs is called
RESPONSE 1. 2. 3. 4. 5.
GRID 6. 7. 8.
Space for Rough Work
 B-86 DPP/ CB22
9. Which of the following statements regarding glucagon is (c) seminiferous tubules and provide nutrition to germ cells
false? (d) pancreas and secrete cholecystokinin
(a) It is secreted by -cells islets of Langerhans. 14. The phase of menstrual cycle in humans that lasts for 7-8
(b) It acts antagonistically to insulin. days, is
(c) It decreases blood sugar level. (a) follicular phase (b) ovulatory phase
(d) The gland responsible for its secretion is heterocrine (c) luteal phase (d) menstruation
gland.
10. Which one of the following statements is correct? 15. Blood glucose level in man is regulated by:
(a) Neurons regulate endocrine activity, but not vice versa. (a) insulin
(b) Endocrine glands regulate neural activity and nervous (b) adrenaline
system regulates endocrine glands. (c) glucagon and insulin
(c) Neither hormones control neural activity nor the (d) All of the above
neurons control endocrine activity. 16. Which of the following glands grows to the maximum size at
(d) Endocrine glands regulate neural activity but not vice puberty and then diminishes gradually?
versa. (a) Thymus (b) Pituitary
11. Match the source gland with respective hormone as well as (c) Thyroid (d) Adrenal
the function correctly. 17. Hypoglycemic hormone is
(a) Insulin (b) Glucagon
Source gland Hormone Function (c) Thyroxine (d) Calcitonin
(a) Anterior Oxytocin Contraction of 18. Which of the following diseases is caused by the under
pituitary uterus muscles secretion of cortisol?
(a) Anaemia
during child
(b) Addison’s disease
birth
(c) Hyperglycemia
(b) Posterior Vasopressin Stimulates (d) Mental illness or retardation
pituitary reabsorption 19. Glycogen is converted to glucose by
of water in the (a) Insulin
distal tubules (b) Glucagon
(c) Galactose
in the nephron
(d) Both glucagons and insulin
(c) Corpus Estrogen Supports 20. A decrease in the level of oestrogen and progesterone
luteum pregnancy causes
(d) Thyroid Thyroxine Regulates (a) Growth and dilation of myometrium
blood calcium (b) Growth of endometrium
level (c) Constriction of uterine blood vessels leading to
sloughing of endometrium or uterine epithelium
12. Which of the following is incorrect? (d) Release of ovum from the ovary.
(a) Iodine is needed for thyroxine formation. 21. Which of the following is a minerelocorticoid?
(b) Calcium regulates the excitibility of nerve fibres. (a) Calciferol (b) Progesterone
(c) Potassium plays an important role in the regulation of (c) Adrenalin (d) Aldosterone
acid base balance in cell. 22. Which hormone interacts with membrane bound receptor
(d) Phosphorus helps to maintain the osmotic pressure of and does not normally enter the target cell ?
the body fluids. (a) Follicle stimulating hormone
13. Sertoli cells are found in (b) Estrogen
(a) ovaries and secrete progesterone (c) Thyroxin
(b) adrenal cortex and secrete adrenaline (d) Cortisol
9. 10. 11. 12. 13.
RESPONSE
14. 15. 16. 17. 18.
GRID
19. 20. 21. 22.
Space for Rough Work
DPP/ CB22 B-87

23. The 24 hour (diurnal) rhythm of our body such as the sleep- 32. Hormones generally cause a response in a cell by
wake cycle is regulated by the hormone (a) interacting directly with the cell’s DNA.
(a) Adrenaline (b) Melatonin (b) binding with a receptor and stimulating protein
(c) Calcitonin (d) Prolactin production.
24. Steroid hormones transmit their information by (c) changing the polarity of the cell membrane and causing
(a) stimulating the receptors present on cell membrance a cascade of events within the cell.
(b) entering into the cell and modifying cellular contents (d) halting all other cellular activity except the required
(c) entering into the cell and modifying nuclear organization response
(d) the help of an intracellular second messenger 33. Hormones are produced at a particular centralized site and
25. Increase in bleeding time and delay in blood coagulation transported throughout the organism by means of
is due to the deficiency of which hormone? (a) a series of synapses
(a) Adrenaline (b) Noradrenaline (b) an integrated neural pathway system.
(c) Parathormone (d) Thyroxine (c) cellular communication
26. Estrogen and testosterone are steroid hormones, and (d) an internal transport system
most likely bind to 34. Injections of a hormone are sometimes given to strengthen
(a) membrane ion channels contractions of the uterus during childbirth. What hormone
might this be?
(b) enzyme-linked membrane reseptors
(a) adrenocorticotropic hormone (ACTH)
(c) G-protein coupled membrane receptors
(b) thyroxine
(d) cytoplasmic receptors
(c) oxytocin (d) insulin
27. The only unicellular exocrine glands in our body are
35. The graph below illustrates the changes in blood sugar
(a) Sweat glands
concentration after a healthy man has drunk a glucose
(b) Mucus secreting goblet cells
solution.
(c) Mammary glands
(d) Sebaceous glands
28. Steroid-based hormones are able to act inside the cell. This
is possible because
(a) there are no receptors for hormones on the cell surface.
(b) hormones must interact with the nucleus to have an
effect.
(c) proteins carry them into the cell.
(d) steroid-based hormones are hydrophobic molecules
that can pass through the cell membrane.
29. Every time you eat a cookie or candy bar, your blood sugar Which one of the following graphs would apply to a diabetic
increases. This triggers an increase in the hormone man in similar circumstances ?
(a) thyroxine. (b) epinephrine.
(c) glucagon. (d) insulin.
30. Target cells (a) (b)
(a) react specifically to a chemical messenger.
(b) have receptors for chemical messengers
(c) secrete hormones
(d) Both a and b
31. Researchers have found increased levels of hormones from
the _____ in the blood of students preparing for final exams.
These hormones are produced in response to stress. (c) (d)
(a) thyroid gland (b) pineal gland
(c) posterior pituitary (d) adrenal glands
23. 24. 25. 26. 27.
RESPONSE
28. 29. 30. 31. 32.
GRID
33. 34. 35.
Space for Rough Work
 B-88 DPP/ CB22
36. A paracrine hormone is 41. Through negative feedback, a hormone may shut off the
(a) a local hormone that acts on the cell that releases it. secretion of an anterior pituitary hormone by :
(b) always acting on a wide variety of target tissues. (a) stimulating the release of a (hypothalamic) releasing
hormone
(c) a local hormone produced at one site but active at a
different site in the body. (b) inhibiting the release of a (hypothalamic) inhibiting
hormone
(d) none of the above
(c) inhibiting the release of a (hypothalamic) releasing
37. “Upregulation” of hormone receptors refers to hormone
(a) increase in hormone receptor numbers with low (d) all of the preceding.
hormone levels. 42. ANF is a peptide hormone and is secrected from
(b) increase in hormone receptor numbers with high (a) Gastrointestinal tract (b) Kidney
neurotransmitter levels (c) Post. Pituitary (d) None of these
(c) increase in hormone levels produced by increase in 43. Steroid hormones –
hormone receptor numbers (a) have only cell surface receptors
(d) decrease in hormone levels produced by decrease in (b) are lipophobic
hormone receptor numbers (c) act through altering the activity of proteins in the target
38. In an experiment, researchers removed the ____ of young cell
mice, and as a result, these mice were able to accept organ (d) are produced by only adrenal cortex.
transplants without rejection. 44. The hormones that initiate ejection of milk, stimulates milk
(a) pineal glands (b) thymus glands production and growth of ovarian follicles are respectively
(c) thyroid glands (d) parathyroid glands known as
(a) PRL, OT and LH (b) OT, PRL and FSH
39. Which of the following is a common second messenger
substance in hormone action ? (c) LH, PRL and FSH (d) PRH, OT and LH
45. A pregnant female deliver a baby who suffers from stunted
(a) Thyroid hormone (b) ADH
growth, mental retardation/low intelligence quotient and
(c) Cyclic AMP (d) Epinephrine abnormal skin. This is the result of :
40. Which of the following glands is considered the “master” (a) Low secretion of growth hormone
endocrine gland in vertebrates ? (b) Cancer of the thyroid gland
(a) Adrenal glands (b) Thyroid gland (c) Over secretion of pars distalis
(c) Hypothalamus (d) Pituitary gland (d) Deficiency of iodine in diet

RESPONSE 36. 37. 38. 39. 40.

GRID 41. 42. 43. 44. 45.

Space for Rough Work

DAILY PRACTICE PROBLEM DPP CHAPTERWISE 22 - BIOLOGY

Total Questions 45 Total Marks 180
Attempted Correct
Incorrect Net Score
Space for Rough Work

Cut-off Score 40 Qualifying Score 50

Success Gap = Net Score – Qualifying Score
Net Score = (Correct × 4) – (Incorrect × 1)
 HINTS & SOLUTIONS

DPP /CB22
1. (a) Cortisol is secreted by the middle region of adrenal cortex. It 13. (c) Sertoli cells are found in the walls of seminiferous tubules of
increases the blood glucose level (which is anti-insulin effect) the testes. They anchor and provide nutrition to the
by converting proteins & fats into glucose. developing germ cells especially the spermatids.
2. (b) Pancreas is a gland which is both exocrine and endocrine. 14. (b) In menstrual cycle, menstrual phase lasts for 4 days,
Cells of acini are exocrine which secrete enzymes and islet proliferating/ovulating phase for about 10 days and secretory
of Langerhans part is endocrine which secretes hormones phase for 14 days.
like insulin, glucagon, etc. 15. (c) 16.(a) 17. (a) 18. (b) 19. (b)
3. (b) Hormones are chemical messengers formed by endocrine cells. 20. (c) 21.(d) 22. (a) 23. (b) 24. (d)
Chemically hormones are of the following types: Amines– 25. (c) Calcium plays an important role in blood clotting.
composed of amino group e.g., Melatonin. Parathormone, a hormone released by parathyroid glands,
Amino acids – eg. thyroxine increases calcium level in the blood. Therefore, deficiency
Peptides –eg. insulin of this hormone will decrease Ca2+ level in the blood, thus
Steroids –eg. aldosterone leading to delay in blood clotting and increase in bleeding
4. (a) Parath amone is a peptide hormone secreted by the time.
parathyroid gland in response to low levels of calcium in the 26. (d) Estrogen and testosterone being steroid hormones are
blood. It acts to maintain normal blood levels of calcium by soluble in lipids, therefore they can cross the plasma
increasing the number of osteoclasts, which break down the membrane and bind to the cytoplasmic receptors to trigger
bone matrix and release calcium into the blood. It also increases their action.
the reabsorption of calcium and magnesium ions in the kidney 27. (b)
tubules, so that their concentration is maintained in the blood. 28. (d) Hydrophobic molecules, such as steroid based hormones,
5. (d) Electroencephalogram is the recording of electric potentials can move easily through the plasma membrane.
originating from different parts of the brain in the form of 29. (d) Insulin acts to lower blood sugar levels.
waves. Fractionation is the technique of rupturing cells and 30. (d) Receptors on target cells react specifically to chemical
separating their components especially cell organelles for messengers. The way they react will determine the cellular
studying their chemistry and functions. Electrophoresis is response.
the technique of separation of charged solutes on the basis of 31. (d) The adrenal glands secrete hormones in response to stress.
their differential migration in an applied electric field. 32. (b) Hormones typically act on a receptor in or on target cells to
6. (b) stimulate the production of proteins.
7. (a) Luteinizing hormone (LH) stimulates ovulation. Deficiency 33. (d) The internal transport system may be the cardiovascular
of insulin causes diabetes mellitus. Deficiency of ADH or system in animals or the xylem and phloem in plants.
vasopressin causes diabetes insipidus. Deficiency of 34. (c) Oxytocin stimulates muscle contractions during childbirth
parathormone causes tetany. Deficiency of thyroxine causes and milk letdown.
cretinism in infants and myxoedema in adults. 35. (c) In diabetics, the rise in blood glucose above the normal level
8. (b) In heart cells AMP acts as secondary messenger which is of 80–90 mg/100ml fails to stimulate the production of insulin
made in the response of adrenaline and it stimulates Ca2+ from the pancreatic -cells of the islets of Langerhans. As a
ions to come out from the sarcoplasmic reticulum of muscle result, the glucose is not removed from the blood to be stored
fibres which causes muscle contraction. in muscle cells as glycogen, resulting in a high blood glucose
cGMP (Cyclic Guanosine Monophosphate) which acts as level for a long period of time.
secondary messenger works on the action of acetylcholine, 36. (c) Paracrine hormones act on local cells that are hormones act
increase in flow of Ca2+ into muscle fibres & hence causes on the very same cells that secrete them.
muscle relaxation. There is no role of sodium in hormonal 37. (a) “Upregulation” of hormone receptors on a cell is the
action. production of more receptors when the hormone is present
9. (c) Pancreas is a heterocrine gland comprising both endocrine over time in the blood or other fluids surrounding the cell.
and exocrine parts. Its endocrine part consists of small 38. (b) Thymic hormones stimulate T cell development.
masses of hormone secreting cells called islets of Langerhans. 39. (c) In many cases, hormones trigger cyclic AMP when they
The -cells of latter secrete glucagons and its -cells secrete bind with the target cells. Cyclic AMP then carries out the
insulin. These two hormones have antagonistic effects on action of the hormone within the cell as a second messenger.
the glucose level in the blood which means that insulin 40. (d) The pituitary gland is considered the master gland because it
decreases the blood glucose level while glucagon increases produces hormones that control endocrine glands throughout
blood glucose level. the body.
10. (a) Neurons regulate endocrine activity, but not vice- 41. (c) Inhibited release of a releasing hormone will lead to a reduction
versa.Neurons in the hypothalamus secrete thyroid releasing in the secretion of a specific anterior pituitary hormone.
hormone (TRH), which stimulates cells in the anterior 42. (d) 43. (c) 44. (b)
pituitary to secrete thyroid-stimulating hormone (TSH). 45. (d) Iodine is essential for the normal rate of hormone synthesis
11. (b) Posterior pituitary releases vasopressin which stimulates in the thyroid. Deficiency of iodine in our diet results in
reabsorption of water in the distal tubules in nephron. hypothyroidism and enlargement of the thyroid gland,
12. (d) Osmotic pressure of body fluids is mainly maintained by the commonly called goitre.
plasma proteins (albumins, globulins) and electrolyte ions Hypothyroidism during pregnancy causes defective
(Na+, K+ etc). Phosphorus has nothing to do with the osmotic development and maturation of the growing baby leading to
pressure of body fluids. stunted growth (cretinism), mental retardation, low
intelligence quotient, abnormal skin, deaf-mutism, etc.