Release Notes

Release Notes
Image Lab™ Software, Version 4.1

Catalog #170-9690
June 15, 2012
This document has the following sections:

1. About Image Lab Software
2. System Requirements
3. Revision History
4. Reporting Software Problems and Feature Requests to Bio-Rad Laboratories
5. Known Issues
1. About Image Lab Software

Image Lab image acquisition and analysis software supports the Gel Doc™ EZ, Gel Doc XR+,
ChemiDoc™ XRS+, and ChemiDoc™ MP imaging systems, providing automated and efficient image
acquisition and analysis through user defined protocols. Researchers can easily design reusable
protocols to generate reproducible data.
Image Lab software enables you to view your analyzed data, adjust the analysis, and produce
customized reports that show precisely what settings have been applied in order to ensure repeatable
results.
2. System Requirements
Component Minimum Recommended

Operating system Windows XP SP3 32-bit Windows XP SP3 Professional 32-bit
Windows 7 32-bit or 64-bit Windows 7 Professional 32-bit or 64-bit
Mac OS X 10.6 Mac OS X 10.7, 10.6
Processor 2.0 GHz Pentium 4 or equivalent Core 2 Duo 2.0 GHz or higher
Hard disk space 20 GB > 100 GB
System memory 1,024 MB > 1,024 MB
Screen resolution 1024 × 768 1280 × 1024 or higher
Ports for connecting instrument 1 free USB 2.0 port 1 free USB 2.0 port
Other software (optional) Microsoft Office 2003 or later (Windows) Microsoft Office 2003 or later (Windows)
Office 2008 or iWorks (Mac) Office 2008 or iWorks (Mac)
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3. Revision History
Version 4.1
 Added support for multichannel lane and band analysis.
 Added Normalization Tools to support total protein normalization or housekeeping proteins in
multichannel images (ChemiDoc MP)
 Added Normalized Volume and Normalization Factor columns to Analysis Table
 Added automated exposure feature for chemi images.
 Added copy and paste for lane frames.
 Added global lane width tool.
 Added keyboard control for lane tools.
Version 4.0.1
 Restored default image transform for chemi images to the version 3.0 default
 Reduce background events during chemi exposures
 Revised image information display
Version 4.0 Rev F

 Corrected Gel Doc EZ user manual PDF chapter numbering
 Updated sample images to version 3.0
Version 4.0 Rev E

 Added support for ChemiDoc MP
 Added support for multichannel images
 Added support for stain-free applications on ChemiDoc MP
 Corrected photometric interpretation of chemi images
 Standard bands are preserved when you change standard lanes
 Standard curve regression method now defaults to point to point
 Added support for lane volume to volume tools
Version 3.0
 Added support for Gel Doc EZ
 Improved Export for Publication and Export for Analysis
 Added image quality improvements providing increased image resolution
 Simplified Chinese localization
 Windows 7 64-bit support
 Fixed printing issues
Version 2.0.1
 Fixed saturation problem during Signal Accumulation Mode (chemi mode)
 Fixed delay on Position Gel on single core computers
 Removed oval artifact when imaging nothing in chemi mode
 Reduced saturation in position step for chemi images
 Maintain image transform of merged images
 Fixed problem saving text annotations
 Added new Mini-PROTEAN® gel for Gel Doc and ChemiDoc protocols
 Added Mac OS X 10.6 support
Version 2.0
 Added support for Gel Doc XR+ and ChemiDoc XRS+
o Installation and calibration wizard
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o Application driven protocol
 Added tutorials and more sample images
 Added Quantitative Analysis tools
o Relative and absolute quantitation
o Improve quantitation of bands
 Improved Lane Profile window
o Added option to adjust band boundaries
o Added option to zoom profile
 Added volume analysis
o Rectangle, round, and freehand volumes
o Volume analysis table
o Volume standard curve
 Added Snapshot function to capture Image Lab-generated graphics to clipboard or file
 Option to adjust Lane Background
 Option to detect bands in a single lane
 Added image merge and image invert functions
 Improved lane and band detection
 Added Start page with recent protocols and images
4. Reporting Software Problems and Feature Requests to Bio-Rad Laboratories

Send all problems and feature requests via email to: ImageLab@Bio-Rad.com. Please specify the
version of the software (Help > About) and provide a detailed description of the problem or feature.
5. Additional Information and Known Issues

 Installation
o When upgrading from Image Lab 2.0/2.0.1 to Image Lab 4.0 on Windows 7, the Gel Doc
XR drivers might not be installed correctly. Turn on the Gel Doc XR and go to the Device
Manager (click Start, then right-click Computer, select Manage and select Device
Manager). Right-click Bio-Rad Imaging Device under Imaging Devices and select Update
Driver Software. Click Search automatically for updated driver software to update the
drivers
 Documentation
o System requirements table in manuals omit Mac OSX 10.7 support. Image Lab 4.1 has
been has been validated and tested for bot Mac OSX 10.7 and 10.6
o Bitmap for Normalization Tools is incorrect and includes an extra button.
 ChemiDoc MP
o You are only allowed to create, edit, or delete custom applications from a single channel
protocol
 ChemiDoc XRS+ and ChemiDoc MP

o Some computers based upon the Intel i3 and i5 processor may capture images with
artifacts. If this occurs, try to remove all other USB devices from the computer and try
connecting the system to a different USB port, or change computers
 All devices
o If the device is not recognized by Image Lab, then close Image Lab, restart the device,
and wait for the operating system to recognize the device. Then restart Image Lab
 Gel Doc XR+, ChemiDoc XRS+, and ChemiDoc MP

o Quantity One® software must be closed before using Image Lab software and vice versa
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o The two different models of the white light conversion screen are interchangeable. The
illustration and part number in Image Lab 4.0 may not exactly match the model of the
white light conversion screen you have
 Quantity One
o If you install Quantity One after you install Image Lab, do not select the Gel Doc XR
Drivers and ChemiDoc XRS/VersaDoc Drivers in the Select Features dialog box of the
Quantity One installer (Windows only)
o If you want to use a USB ChemiDoc XRS+ with Quantity One, you must also install
Image Lab so that the correct driver is installed (Windows only). For the Macintosh you
must install the driver located in the ‘Q1 USB ChemiDoc XRS’ folder (Macintosh only)
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Contacting Technical Support
To contact your local Bio-Rad Technical Support office, go to www.bio-rad.com/contact and find the
telephone number for your area.
For Technical Support in the U.S., call 1-800-424-6723.
Copyright © 2012, Bio-Rad Laboratories, Inc. All Rights Reserved. Windows and Office are trademarks of
Microsoft Corporation. Macintosh, Mac OS and iWorks are trademarks of Apple Inc.
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Release Notes

Image Lab™ Software, Version 4.1

This document has the following sections:

1. About Image Lab Software

Component Minimum Recommended

Version 4.0 Rev F

Version 4.0 Rev E

4. Reporting Software Problems and Feature Requests to Bio-Rad Laboratories

5. Additional Information and Known Issues

 ChemiDoc XRS+ and ChemiDoc MP

 Gel Doc XR+, ChemiDoc XRS+, and ChemiDoc MP

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