EC Life Sciences Grade 12 June 2023 QP and Memo
EC Life Sciences Grade 12 June 2023 QP and Memo
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NATIONAL
SENIOR CERTIFICATE
GRADE 12
JUNE 2023
LIFE SCIENCES
MARKS: 150
TIME: 2½ hours
4. Number the answers correctly according to the numbering system used in this
question paper.
8. The diagrams in this question paper are NOT necessarily drawn to scale.
SECTION A
QUESTION 1
1.1 Various options are given as possible answers to the following questions.
Choose the answer and write only the letter (A–D) next to the question numbers
(1.1.1 to 1.1.10) in the ANSWER BOOK, for example 1.1.11 D.
A Fertilisation
B Mitosis
C Morula
D Meiosis
1.1.2 The diagram shows a human 28-day menstrual cycle divided into four
parts P, Q, R and S. The ovum is released on day 14.
A P
B Q
C R
D S
A 1
B 2
C 3
D 4
A Deoxyribose-adenine-thymine
B Adenine-ribose-phosphate
C Deoxyribose-thymine-phosphate
D Uracil-deoxyribose-phosphate
A 20
B 40
C 30
D 60
1.1.7 The following table shows the events of mitosis and meiosis I.
MITOSIS MEIOSIS I
(i) The number of chromosomes The number of chromosomes is
remains the same halved
(ii) Daughter cells formed are Daughter cells formed are
genetically different from genetically identical to each
each other other
(iii) Single chromosomes are Homologous chromosomes
arranged at the equator pairs are arranged at the
during metaphase equator during metaphase
(iv) Two daughter cells are Four daughter cells are formed
formed
A B C
A Centrosome Cell wall Chromatid
B Centromere Cell membrane Chromosome
C Centromere Cell membrane Chromatid
D Centrosome Cell membrane Chromatid
1.1.9 Which ONE of the following shows the correct sequence of the phases
in meiosis?
A 3, 1, 2, 4
B 2, 1, 3, 4
C 1, 3, 2, 4
D 1, 2, 3, 4
(10 x 2) (20)
1.2 Give the correct biological term for each of the following descriptions. Write
only the term next to the question numbers (1.2.1 to 1.2.7) in the ANSWER
BOOK.
1.2.2 The name of the process when homologous chromosome pairs fail
to separate during meiosis
1.2.3 The number, shape and arrangement of all the chromosomes in the
nucleus of a somatic cell
1.2.6 Eggs are retained/hatch in the female body and the young are born
live
COLUMN I COLUMN II
1.3.1 Phase during which cytokinesis takes A: Telophase I
place B: Telophase II
1.3.2 Development in birds that is complete A: Precocial development
such that the young are born B: Altricial development
independent, with eyes open, with
down feathers and able to move or
feed independently
1.3.3 Collects nitrogenous waste and A: Chorion
assists in the exchange of gases B: Allantois
(3 x 2) (6)
1.4 In watermelons, there are two alleles for taste, bitter fruit and sweet fruit. The
allele for bitter fruit (B) is dominant over the allele for sweet fruit (b). There are
two alleles for skin appearance, yellow spots and no spots. The allele for
yellow spots (N) is dominant over the allele for no spots (n).
Plant A, which is heterozygous for bitter fruit and yellow spots, was crossed
with plant B, which has sweet fruit and no spots.
1.4.1 Give the term that describes a genetic cross involving two
characteristics. (1)
1.4.2 Give:
1.4.3 List TWO ways in which the phenotype of a watermelon with genotype
bbNn differs from the phenotype of a watermelon with genotype Bbnn. (2)
1.5 The diagram below shows a genetic engineering process. A donor cell was
taken from the skin cell of a male pig to create a new offspring.
1.5.1 Name the genetic engineering process shown in the diagram above. (1)
TOTAL SECTION A: 50
SECTION B
QUESTION 2
C G
T A
G C
A T
2.1.1 Name the structures inside the nucleus that contain DNA. (1)
2.1.2 Besides the nucleus, name ONE other place in a cell where DNA is
found. (1)
2.1.4 The coded message in DNA is used in the process of protein synthesis.
Name and describe the stage during protein synthesis responsible for
the copying of the coded message from DNA.
(*1 compulsory mark + Any 5) (6)
The diagram below shows part of a gene coding for the enzyme IDUA.
Strand X from
C T C A T A C A G C T C a person
without
syndrome H
Strand Y from
C T C A T A T A G C T C a person
with
syndrome H
The table below shows mRNA anticodons and the amino acids they code for.
2.2.2 Give the DNA triplet on strand Y that codes for the amino acid glutamic
acid. (1)
2.2.3 Strand Y shows a mutation in the DNA which has caused syndrome
H.
Explain how the mutation could cause the enzyme not to work. (5)
2.4 The graphs below show the blood hormone concentration of two ovarian
hormones and changes that occur in the uterus lining during a 28-day cycle of
a woman.
Hormone Y
Blood hormone
Hormone X
concentration
0 7 14 21 28
Time / days
Thickness of uterus
lining hormone
concentration
0 7 14 21 28
Time / days
2.4.2 Explain the reason for your answer to QUESTION 2.4.1 by referring to
both graphs. (2)
2.4.3 State the biological term used for the uterus lining. (1)
2.4.4 Explain whether fertilisation occurred during the cycle of this woman. (3)
2.4.5 Name and describe how the two hormones secreted from the pituitary
gland control the menstrual cycle. (4)
2.5 Cadasil is an inherited disorder which leads to the weakening of blood vessels
in the brain. It is caused by a dominant allele (D).
(b) Give evidence from the pedigree diagram that Cadasil is caused
by a dominant allele. (1)
2.5.2 (a) Is Sam homozygous or heterozygous for the Cadasil allele? (1)
Use a genetic cross to find the percentage chance that the new baby
will develop into a person with Cadasil. (6)
2.6 Read the passage below and answer the questions that follow.
Scientists are trying to develop treatment for Cadasil by using stem cells.
Specially treated stem cells would be injected into the damaged part of the
brain. Embryonic stem cells can be obtained by removing a few cells from a
human embryo. Scientists have discovered how to change adult skin cells into
stem cells.
2.6.1 Why would scientists use stem cells in the treatment of Cadasil? (3)
2.6.2 Suggest ONE advantage of using stem cells from adult skin cells than
from embryos. (1)
[50]
QUESTION 3
3.1 The diagram shows sperm cells, viewed using a microscope, from two different
men.
3.1.1 Use the information in the diagram to give TWO reasons why man A is
more fertile than man B. (2)
3.1.2 Discuss TWO structural adaptations of the sperm cells to reach the
ovum in the Fallopian tube of the female. (4)
3.1.3 “The father determines the gender of a baby.” Explain why this
statement can be regarded as true. (3)
3.2.1 Name the part of the ear that contains structures B, C and D. (1)
3.2.4 Tube A may be blocked when a person has a throat infection. Name
tube A and explain why it would be dangerous for such a person to go
skydiving. (4)
3.2.5 Explain how the eardrum and the oval window contribute to the
amplification of sound. (2)
3.3 The diagram below shows a bee flying towards a man’s eye.
Eyelid
As the bee approaches the man’s eye, light from the bee reaches the light
sensitive cells in the eye. The muscles in the eyelid shut the man’s eye before
the bee hits his eye.
3.3.1 Name the type of response that results in the shutting of the man’s
eye before the bee hits his eye. (1)
3.3.2 Describe the pathway taken by the nerve impulse to cause the
response mentioned in QUESTION 3.3.1. (5)
3.3.3 The population of the USA is 322 million, of which 151,34 million are
over 40 years of age. 17,2% of the people over the age of 40 develop
a cataract.
(a) Explain how a cataract would affect the ability to see. (2)
(b) Calculate the number of people in the USA over the age of 40
who develop a cataract. (3)
3.4.2 Calculate the average distance indicated as X in the table above. (2)
3.4.3 State ONE way in which the reliability of the investigation was ensured. (1)
3.4.4 Suggest TWO ways in which the reliability of this investigation can be
improved. (2)
3.4.5 Plot a bar graph showing the average distance the ruler fell before it was
caught before and after drinking coffee. (6)
3.4.6 The scientists used the reading on the ruler as a measure of the reaction
time.
By looking at the results what can you conclude about the effect of
caffeine on reaction time. (2)
[50]
NATIONAL
SENIOR CERTIFICATE
GRADE 12
JUNE 2023
LIFE SCIENCES
MARKING GUIDELINE
MARKS: 150
2. If, for example, three reasons are required and five are given
Mark the first three irrespective of whether all or some are correct/incorrect.
9. Non-recognised abbreviations
Accept if first defined in answer. If not defined, do not credit the
unrecognised abbreviation, but credit the rest of the answer if correct.
14. If only the letter is asked for, but only the name is given (and vice versa)
Do not credit.
17. Caption
All illustrations (diagrams, graphs, tables, etc.) must have a caption.
SECTION A
QUESTION 1
1.1 1.1.1 B ✓✓
1.1.2 A ✓✓
1.1.3 A ✓✓
1.1.4 B ✓✓
1.1.5 A ✓✓
1.1.6 D ✓✓
1.1.7 C ✓✓
1.1.8 C ✓✓
1.1.9 C ✓✓
1.1.10 C ✓✓ (10 x 2) (20)
1.2.2 Non-disjunction ✓
1.2.3 Karyotype ✓
1.2.4 Haemophilia ✓
1.2.5 Meninges ✓
1.2.6 Ovovivipary ✓
1.3.2 A only ✓✓
(b) 38 ✓ (1)
TOTAL SECTION A: 50
SECTION B
QUESTION 2
2.1.2 - Mitochondria ✓
- Chloroplasts ✓
(Mark first ONE only) (1)
2.1.4 - Transcription✓*
- The double helix DNA unwinds ✓
- The double-stranded DNA unzips ✓/weak hydrogen bonds break
- to form two separate strands ✓
- One strand is used as a template ✓
- to form mRNA ✓
- using free RNA nucleotides from the nucleoplasm ✓
- The mRNA is complementary to the DNA ✓/A complements U, G
complements C
- mRNA now has the coded message for protein synthesis ✓
1 compulsory mark + Any 5 (6)
2.5 2.5.1 (a) An allele that is expressed (shown) in the phenotype when found
in the heterozygous and homozygous condition ✓ (1)
(b) Two parents (Tom and Lee) both with Cadasil have a child
(Abby/ Bob) without Cadasil ✓
OR
If recessive all of Tom and Lee’s children would have Cadasil ✓ (1)
OR
Genotype Dd x dd ✓
Meiosis
G/gametes D, d x d, d✓
Fertilisation
OR
Genotype Dd x dd ✓
Meiosis
Gametes D d
Fertilisation d Dd dd
d Dd dd
2.6.2 It is less controversial ✓using skin cells than embryonic cells. (1)
[50]
QUESTION 3
OR
Man B has
- Fewer /not enough/lesser sperms
- abnormally shaped /unhealthy sperms (2)
3.1.2 - Sperm has a neck area with large amount of mitochondria which
will produce energy for the sperm to move to the Fallopian tube.
- Sperm has a tail which propel the sperm/make movements so
the sperm could move to the Fallopian tube (2 x 2) (4)
3.2.3 - The bones will not move and vibrate in reaction to sound
- resulting in hearing loss (2)
3.2.5 The surface area of the eardrum is larger than that of the oval window, ✓
thus a greater force is concentrated into a smaller area. ✓ (2)
3.3.3 (a) - cataract scatters and blocks the light ✓ as it passes through
the lens,
- preventing a sharply defined image from reaching your retina ✓
- as a result, your vision becomes blurred ✓ (Any 2 x 1) (2)
(b) 17,2
✓ x 151,34 ✓ million = 26,03 million ✓ (3)
100
3.4.2 99
(8 + 13 + 11 + 17 + 10 + 14 + 13 + 13) = = 12,4 ✓ (2)
8
3.4.5
Distance the ruler fell before it was caught before
and after drinking coffee
20
18
16
Distance the ruler fell (cm)
14
12
10
0
Average distance before drinking coffee Average distance after drinking coffee.
NOTE:
If the wrong type of graph is drawn, marks will be lost for:
• Correct type of graph
• Plotting of the graph
The axes can be transposed.
A bar graph can have horizontal bars. (6)