Grannys List

Granny Storm Crow's MMJ Reference List- January 2012
Well, here I am again, staring at this blank screen, trying to figure out what to say so you will share the information I have gathered. Once the medical facts about cannabis become known, the need for legalization becomes obvious! How many times have I said that? I need YOU to educate those around you. I cant do it alone! At times, it seems so futile- this never-ending battle against ignorance about cannabis. But I cant give up - this simple herb has some amazing uses and people need to know what it can do. Cannabis should be treated like any other medicinal herb, because thats what it is, just an herbal medicine with a rather pleasant side effect- you feel high. Unlike common aspirin, cannabis never kills by overdose. Compared to some pharmaceutical drugs side effects, the cotton-mouth, red eye, munchies and feeling a just bit too good from using cannabis seems so trivial! As Americans, we should be free to exercise our right to choose the type of medicines that we take. Anyone exhibiting the first signs of Alzheimers should be able to choose between Aricept, Marinol, or natural cannabis to slow the deposit of mind-clogging amyloid plaque. When tested at double the concentration of THC, Aricept blocked plaque formation only 22% as well as THC, and Cognex blocked plaque formation only 7% as well as THC. (Marijuana May Slow Alzheimer's - WebMD, 2006) Marinol is just a capsule of a pure synthetic THC dissolved in sesame oil. It will work, but some people find that it causes anxiety because it lacks CBD (cannabidiol) to balance the THC high. Natural cannabis has CBD and other cannabinoids in it, which act in a different way to slow the progress of Alzheimers. (Cannabidiol and other cannabinoids reduce microglial activation in vitro and in vivo: relevance to Alzheimers disease - Molecular Pharmacology, 2011) I know which I would logically choose, but in 2/3s of the US, and everywhere by federal law, that choice is forbidden to us. Our government has banned our best choice! Then there are thousands facing the severe nausea of chemotherapy- will they be able to keep an antinausea pill down long enough for it to work? Wouldnt it be simpler to inhale some cannabis vapor, or smoke, and get almost instantaneous relief? In 16 states, you can! And the pain from cancer? Medical Marijuana a Success in Israel More than two-thirds of cancer patients who were prescribed medical marijuana to combat pain are reportedly satisfied with the treatment Are we less free than the Israelis? They are free to get legal, prescribed cannabis for cancer pain- are you? Our neighbor, Canada, has legal medical cannabis, and their government grows cannabis for patients! And surprise! The US has 4 federally legal MMJ patients and grows for them. The program is closed. No new patients allowed! Why? And why is cannabis research, all but banned in the US? This prohibitionist foolishness has to end! 2012 is supposed to be a time of change, an interesting year. It is time for us to demand a change in the laws on cannabis! We must keep telling the truth, keep presenting the facts to our friends and our families. The facts are there in PubMed- cannabis IS medicine! Our government lies to us about cannabis! And folks- If the truth wont do, then something is wrong!
It Is Time for Marijuana to Be Reclassified as Something Other Than a Schedule I Drug! (2005) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1681626&tool=pmcentrez
ACEA/ ARACHIDONYL-2'-CHLOROETHYLAMIDE - synthetic, CB1 agonist The cannabinoids R(-)-7-hydroxy-delta-6-tetra-hydrocannabinol-dimethylheptyl (HU210), 2-O-arachidonoylglycerylether (HU-310) and arachidonyl-2-chloroethylamide (ACEA) increase isoflurane provoked sleep duration by activation of cannabinoids 1 (CB1)-receptors in mice. (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/12095655 In vivo effects of CB1 receptor ligands on lipid peroxidation and antioxidant defense systems in the rat brain of healthy and ethanol-treated rats. (full 2006)
http://www.if-pan.krakow.pl/pjp/pdf/2006/6_876.pdf
Arachidonyl-2'-chloroethylamide, a highly selective cannabinoid CB1 receptor agonist, enhances the anticonvulsant action of valproate in the mouse maximal electroshockinduced seizure model. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16930590 Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence. (full - 2007)
http://jpet.aspetjournals.org/content/322/3/1144.long
Ultra-low dose cannabinoid antagonist AM251 enhances cannabinoid anticonvulsant effects in the pentylenetetrazole-induced seizure in mice. (abst 2007)
http://www.ncbi.nlm.nih.gov/pubmed/17870135
Attenuation of Experimental Autoimmune Hepatitis by Exogenous and Endogenous Cannabinoids: Involvement of Regulatory T Cells (full - 2008)
http://molpharm.aspetjournals.org/content/74/1/20.full?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=cannabinoid&searchid=1&FIRSTINDEX=320&resourcetype=HWCIT#content-block
Cannabinoid modulation of cutaneous Adelta nociceptors during inflammation. (full 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585399/?tool=pubmed Cannabinoid-mediated antinociception is enhanced in rat osteoarthritic knees. (full 2008) http://onlinelibrary.wiley.com/doi/10.1002/art.23156/full Cannabinoid receptor activation induces apoptosis through tumor necrosis factor alphamediated ceramide de novo synthesis in colon cancer cells. (full 2008)
http://clincancerres.aacrjournals.org/content/14/23/7691.long
Endogenous cannabinoids induce fever through the activation of CB1 receptors. (full 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765314/?tool=pubmed
The effects of intracerebroventricular AM-251, a CB1-receptor antagonist, and ACEA, a CB1-receptor agonist, on penicillin-induced epileptiform activity in rats. (full 2009)
http://onlinelibrary.wiley.com/doi/10.1111/j.1528-1167.2009.02098.x/full
Involvement of nitrergic system in the anticonvulsant effect of the cannabinoid CB(1) agonist ACEA in the pentylenetetrazole-induced seizure in mice. (abst 2009)
Involvement of nitric oxide in the gastroprotective effect of ACEA, a selective cannabinoid CB1 receptor agonist, on aspirin-induced gastric ulceration. (abst 2009)
Effect of arachidonyl-2'-chloroethylamide, a selective cannabinoid CB1 receptor agonist, on the protective action of the various antiepileptic drugs in the mouse maximal electroshock-induced seizure model. (abst 2009)
Role of cannabinoid CB1 receptors on macronutrient selection and satiety in rats. (abst 2009) http://www.ncbi.nlm.nih.gov/pubmed/19150453 Regulatory Role of Cannabinoid Receptor 1 in Stress-Induced Excitotoxicity and Neuroinflammation (abst - 2010)
http://www.nature.com/npp/journal/vaop/ncurrent/full/npp2010214a.html
Alkamides and a neolignan from Echinacea purpurea roots and the interaction of alkamides with G-protein-coupled cannabinoid receptors. (abst 2011)
L-Type Calcium Channel Mediates Anticonvulsant Effect of Cannabinoids in Acute and Chronic Murine Models of Seizure. (abst 2011)
Changes in the cannabinoid (CB1) receptor expression level and G-protein activation in kainic acid induced seizures. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22079489 Protective effect of cannabinoid CB1 receptor activation against altered intrinsic repetitive firing properties induced by A neurotoxicity. (abst 2012)
Opposing Roles for Cannabinoid Receptor Type-1 (CB(1)) and Transient Receptor Potential Vanilloid Type-1 Channel (TRPV1) on the Modulation of Panic-Like Responses in Rats. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/21937980 Contrasting protective effects of cannabinoids against oxidative stress and amyloid- evoked neurotoxicity in vitro. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/22233683
ACHILLES TENDINOSIS Increased Expression of Cannabinoid CB(1) Receptors in Achilles Tendinosis. (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169627/?tool=pubmed
ACNE The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities. (full 2009)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757311/?tool=pubmed
Endocannabinoid signaling and epidermal differentiation. (abst 2011)

ADD/ ADHD ADHD by Ryan P (anecdotal - no date)

http://www.rxmarijuana.com/shared_comments/ADHD4.htm
Marijuana and ADD Therapeutic uses of Medical Marijuana in the treatment of ADD (no date) http://www.onlinepot.org/medical/add&mmj.htm Barba Jacob and the history of marihuana
(abst 1986) (no date - 2008)
How Cannabis Compares to other treatments Recipe For Trouble
http://dcsafeaccess.org/medical/how-cannabis-compares-to-other-treatments/
(anecdotal/ news - 2002 )
http://www.cbsnews.com/stories/2002/03/05/48hours/main503022.shtml
Association between cannabinoid receptor gene (CNR1) and childhood attention deficit/hyperactivity disorder in Spanish male alcoholic patients (full - 2003)
http://www.nature.com/mp/journal/v8/n5/full/4001278a.html
Cannabinoids effective in animal model of hyperactivity disorder Cannabis 'Scrips to Calm Kids? (news - 2004)
(abst - 2003)
http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=162#4
http://www.foxnews.com/story/0,2933,117541,00.html
Fitness to drive in spite (because) of THC
(abst - 2007)
http://www.unboundmedicine.com/medline/ebm/record/17879702/abstract/%5BFitness_to_drive_in_spite_ _because__of_THC%5D
Science: THC normalized impaired psychomotor performance and mood in a patient with hyperactivity disorder (news - 2007)
http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=254
Association of the Cannabinoid Receptor Gene (CNR1) With ADHD and Post-Traumatic Stress Disorder (full - 2008)
Cannabis Improves Symptoms of ADHD Cannabis use and adult ADHD symptoms.
(full - 2008) (abst - 2008) (news - 2008)
http://www.cannabis-med.org/english/journal/en_2008_01_1.pdf
Autism, ADD, ADHD and Marijuana Therapy

http://www.entheology.org/edoto/anmviewer.asp?a=319
Cannabinoid receptors in brain: pharmacogenetics, neuropharmacology, neurotoxicology, and potential therapeutic applications (abst 2009) http://pharmgkb.org/pmid/19897083 Why I Give My 9-year-old Pot (anecdotal/news - 2009) (news/anecdotal - 2009) (news - 2010)
http://www.slate.com/id/2251174/
http://www.doublex.com/section/health-science/why-i-give-my-9-year-old-pot
Why I Give My 9-Year-Old Pot, Part II Why I Give My 9-Year-Old Pot, Part 3
http://www.doublex.com/section/health-science/why-i-give-my-9-year-old-pot-part-ii
Science: Cannabis effective in the treatment of TOURETTE Syndrome and attention deficit hyperactivity disorder (ADHD) (news 2010)
http://www.cannabismed.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=323&search_pattern=tourette#2
Loss of striatal cannabinoid CB1 receptor function in attention-deficit/hyperactivity disorder mice with point-mutation of the dopamine transporter. (abst 2011)
Why I Give My Autistic Son Pot, Part 4

http://www.slate.com/id/2294072/?from=rss
(news 2011)
ADDICTION An Abstinence Syndrome Following Chronic Administration of Delta-9terahydrocannabinol in Rhesus Monkeys. (abst 1980)
Abuse potential of dronabinol (Marinol).

(abst 1998) (full - 1990)
Relative Addictiveness of Various Substances

http://www.ukcia.org/research/addictiv.htm
Genetic differences in delta 9-tetrahydrocannabinol-induced facilitation of brain stimulation reward as measured by a rate-frequency curve-shift electrical brain stimulation paradigm in three different rat strains. (abst 1996)
Anandamide, an Endogenous Cannabinoid, Has a Very Low Physical Dependence Potential (full - 1998)
http://jpet.aspetjournals.org/content/287/2/598.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext= cannabinoid&searchid=1&FIRSTINDEX=480&resourcetype=HWCIT
Delta9-tetrahydrocannabinol releases and facilitates the effects of endogenous enkephalins: reduction in morphine withdrawal syndrome without change in rewarding effect. (abst 2001) http://www.ncbi.nlm.nih.gov/pubmed/11359533 Chronic Morphine Modulates the Contents of the Endocannabinoid, 2-Arachidonoyl Glycerol, in Rat Brain (full - 2003)
http://www.nature.com/npp/journal/v28/n6/full/1300117a.html
Does Cannabis Use Predict Poor Outcome for Heroin-dependent Patients on Maintenance Treatment? Past Findings and More Evidence Against. (abst 2003)
http://medical-journals.healia.com/doc/12603227/Does-cannabis-use-predict-poor-outcome-for-heroindependent-patients-on-maintenance-treatment-Past-findings-and-more-evidence-against
Cannabis Abuse is Not a Risk Factor for Treatment Outcome in Methadone Maintenance Treatment: a 1-year Prospective Study in an Israeli Clinic. (abst 2004)
Alcohol Consumption Moderates the Link Between Cannabis Use and Cannabis Dependence in an Internet Survey. (abst 2005)
http://psycnet.apa.org/journals/adb/19/2/212/
Confirming alcohol-moderated links between cannabis use and dependence in a national sample (abst 2006) http://www.sciencedirect.com/science/article/pii/S0306460305002959
Long term marijuana users seeking medical cannabis in California (20012007): demographics, social characteristics, patterns of cannabis and other drug use of 4117 applicants (full - 2007) http://www.harmreductionjournal.com/content/4/1/16 Lack of behavioral sensitization after repeated exposure to THC in mice and comparison to methamphetamine (full - 2007)
Merck Manual - Marijuana (Cannabis)
(excerpt - 2008) (news 2008)
http://www.merckmanuals.com/professional/sec23/ch352/ch352i.html?qt=marijuana&alt=sh
Study of 4000 indicates marijuana discourages use of hard drugs.

http://www.csdp.org/publicservice/medicalmj08.htm
Calling B.S. on the Idea of 'Marijuana Addiction'

http://www.alternet.org/drugs/80408/?page=entire
(news 2008)
When Your Kid Smokes Pot
(news 2008)
http://mensnewsdaily.com/2010/08/08/when-your-kid-smokes-pot/
Adolescent Exposure to Chronic Delta-9-Tetrahydrocannabinol Blocks Opiate Dependence in Maternally Deprived Rats (full - 2009)
http://www.nature.com/npp/journal/v34/n11/full/npp200970a.html
The Surprising Effect Of Marijuana On Morphine Dependence
(news - 2009)
http://www.redorbit.com/news/health/1716066/the_surprising_effect_of_marijuana_on_morphine_depende nce/
Active Ingredient In Cannabis Eliminates Morphine Dependence In Rats

http://www.sciencedaily.com/releases/2009/07/090706090440.htm
(news - 2009)
Four percent of adults worldwide using cannabis
(news 2009)
http://www.independent.co.uk/life-style/health-and-families/health-news/four-percent-of-adults-worldwideusing-cannabis-1804190.html
Medical marijuana users in substance abuse treatment. Teen Pot Smoking Won't Lead to Other Drugs as Adults
(full 2010) (news - 2010)
http://www.webmd.com/parenting/news/20100902/teen-pot-smoking-wont-lead-to-other-drugs-as-adults
Aerobic Exercise Training Reduces Cannabis Craving and Use in Non-Treatment Seeking Cannabis-Dependent Adults (full 2011)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050879/?tool=pmcentrez
Abuse potential and psychoactive effects of -9-tetrahydrocannabinol and cannabidiol oromucosal spray (Sativex), a new cannabinoid medicine. (abst 2011)
Dronabinol for the treatment of cannabis dependence: a randomized, double-blind, placebo-controlled trial. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21310551/abstract/Dronabinol_for_the_treatment_ of_cannabis_dependence:_a_randomized_double_blind_placebo_controlled_trial_
The genetic basis of the endocannabinoid system and drug addiction in humans (abst 2011) http://jop.sagepub.com/content/early/2011/09/20/0269881111416689 Exercise can reduce cannabis use in persons who don't want to stop (news 2011)
http://www.news-medical.net/news/20110304/Exercise-can-reduce-cannabis-use-in-persons-who-dontwant-to-stop.aspx
Medical marijuana laws in 50 states: Investigating the relationship between state legalization of medical marijuana and marijuana use, abuse and dependence. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/22099393
2-AG / 2-ARACHIDONOYLGLYCEROL - endocannabinoid, CB1 & CB 2 agonist 2-Arachidonoylgylcerol: A Possible Endogenous Cannabinoid Receptor Ligand in Brain (abst 1995) http://www.sciencedirect.com/science/article/pii/S0006291X85724370 A Second Endogenous Cannabinoid That Modulates Long-term Potentiation. (abst 1997)
http://medical-journals.healia.com/doc/9285589/A-second-endogenous-cannabinoid-that-modulates-longterm-potentiation
Brain Chemicals Mimic Marijuana

http://www.ukcia.org/research/anandami.php
(news - 1997)
2-Arachidonoyl-glycerol as an "endocannabinoid": limelight for a formerly neglected metabolite. (abst - 1998) http://www.ncbi.nlm.nih.gov/pubmed/9526090 Evidence That the Cannabinoid CB1 Receptor Is a 2-Arachidonoylglycerol Receptor (full 1999) http://www.jbc.org/content/274/5/2794.long Endocannabinoids control spasticity in a multiple sclerosis model (full - 2000)
http://www.fasebj.org/cgi/reprint/000399fjev1?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=cannabis&andorexactfulltext=and&sear chid=1&FIRSTINDEX=10&sortspec=relevance&resourcetype=HWCIT
Endocannabinoid 2-arachidonyl glycerol is a full agonist through human type 2 cannabinoid receptor: antagonism by anandamide. (full 2000)
http://molpharm.aspetjournals.org/content/57/5/1045.long
Endocannabinoids and Vascular Function

(full - 2000) (abst - 2000)
Cardiovascular effects of endocannabinoids--the plot thickens.
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=10785543&dopt=abstrac tplus
Despite substantial degradation, 2-arachidonoylglycerol is a potent full efficacy agonist mediating CB(1) receptor-dependent G-protein activation in rat cerebellar membranes. (full 2001) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1572991/?tool=pubmed Endogenous cannabinoids mediate hypotension after experimental myocardial infarction (full - 2001)
http://content.onlinejacc.org/cgi/content/full/38/7/2048?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=cannabinoid&searchid=1&FIRSTINDEX=560&resourcetype=HWCIT
Inhibition of Rat C6 Glioma Cell Proliferation by Endogenous and Synthetic Cannabinoids. Relative Involvement of Cannabinoid and Vanilloid Receptors (full - 2001) http://jpet.aspetjournals.org/content/299/3/951.full Cannabinoid CB1-receptor mediated regulation of gastrointestinal motility in mice in a model of intestinal inflammation (full - 2001)
2-Arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor (full - 2001) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC31108/ An endogenous cannabinoid (2-AG) is neuroprotective after brain injury. (abst - 2001) http://www.ncbi.nlm.nih.gov/pubmed/11586361 Sourcing the Code: Searching for the Evolutionary Origins of Cannabinoid Receptors, Vanilloid Receptors, and Anandamide (full 2002)
http://www.cannabis-med.org/data/pdf/2002-01-3.pdf
Activation of PAF receptors results in enhanced synthesis of 2-arachidonoylglycerol (2AG) in immune cells (full - 2002)
http://www.fasebj.org/cgi/content/full/15/12/2171?maxtoshow=&hits=10&RESULTFORMAT=&fulltext= cannabis&andorexactfulltext=and&searchid=1&FIRSTINDEX=10&sortspec=relevance&resourcetype=H WCIT
The potent emetogenic effects of the endocannabinoid, 2-AG (2-arachidonoylglycerol) are blocked by delta(9)-tetrahydrocannabinol and other cannnabinoids. (full 2002)
Comparison of the enzymatic stability and intraocular pressure effects of 2arachidonylglycerol and noladin ether, a novel putative endocannabinoid. (full 2002)
http://www.iovs.org/content/43/10/3216.full
Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2-arachidonoyl glycerol. (full 2002)
Changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine. (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/12393235 Endocannabinoids protect the rat isolated heart against ischaemia
(full - 2003)
Chronic Morphine Modulates the Contents of the Endocannabinoid, 2-Arachidonoyl Glycerol, in Rat Brain (full - 2003)
Role of Endogenous Cannabinoids in Synaptic Signaling
(full - 2003)
http://physrev.physiology.org/cgi/content/full/83/3/1017?maxtoshow=&hits=80&RESULTFORMAT=&ful ltext=cannabinoid&searchid=1&FIRSTINDEX=160&resourcetype=HWCIT
The Endogenous Cannabinoid System Regulates Seizure Frequency and Duration in a Model of Temporal Lobe Epilepsy (full - 2003)
Manipulation of the endocannabinoid system by a general anaesthetic.

(full 2003)
Cannabinoid influences on palatability: microstructural analysis of sucrose drinking after delta(9)-tetrahydrocannabinol, anandamide, 2-arachidonoyl glycerol and SR141716. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12447606 Short-term fasting and prolonged semistarvation have opposite effects on 2-AG levels in mouse brain. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12914975 The endocannabinoid system: a general view and latest additions
(full - 2004)
New perspectives in the studies on endocannabinoid and cannabis: 2arachidonoylglycerol as a possible novel mediator of inflammation (full - 2004)
http://www.jstage.jst.go.jp/article/jphs/96/4/367/_pdf
2-Arachidonoylglycerol A Novel Inhibitor of Androgen-Independent Prostate Cancer Cell Invasion (full - 2004)
http://cancerres.aacrjournals.org/cgi/content/full/64/24/8826?ijkey=951f5f9d238bdf059cf30ee2be3a5a31aa f2b094
The endocannabinoid-CB receptor system: Importance for development and in pediatric disease. (abst - 2004) http://www.ncbi.nlm.nih.gov/pubmed/15159678
10
A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells (full 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1450257/ Analgesia through endogenous cannabinoids (full - 2005)
http://www.cmaj.ca/cgi/content/full/173/4/357?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=end ocannabinoid&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=date&resourcetype=HW CIT
CB1 cannabinoid receptor-mediated modulation of food intake in mice

(full - 2005)
Effects of cannabinoids on colonic muscle contractility and tension in guinea pigs. (full 2005) http://www.jstage.jst.go.jp/article/jnms/72/1/72_43/_article The endocannabinoid 2-AG protects the blood-brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines. (abst - 2005)
http://lib.bioinfo.pl/pmid:16364651
Finding of endocannabinoids in human eye tissues: implications for glaucoma. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/15823551 Body's Own Marijuana-Like Compounds Are Crucial For Stress-Induced Pain Relief (news - 2005) http://www.sciencedaily.com/releases/2005/06/050628064435.htm Regulation, Function, and Dysregulation of Endocannabinoids in Models of Adipose and -Pancreatic Cells and in Obesity and Hyperglycemia (full - 2006)
http://jcem.endojournals.org/cgi/content/full/91/8/3171?ijkey=83a68cef202eafe129332eda53eee8eb613499 82
Endocannabinoids, feeding and suckling from our perspective

http://www.nature.com/ijo/journal/v30/n1s/full/0803274a.html
(full 2006)
Not Too Excited? Thank Your Endocannabinoids
(full - 2006)
http://www.sciencedirect.com/science/article/pii/S0896627306005927
Experimental autoimmune encephalomyelitis disrupts endocannabinoid-mediated neuroprotection (full - 2006)

Weight Control in Individuals With Diabetes
(full - 2006)
http://care.diabetesjournals.org/content/29/12/2749.full?maxtoshow=&hits=80&RESULTFORMAT=&full text=cannabis&searchid=1&FIRSTINDEX=2000&resourcetype=HWCIT
A new strategy to block tumor growth by inhibiting endocannabinoid inactivation. (full 2006) http://www.fasebj.org/content/early/2004/10/02/fj.04-1754fje.long Involvement of the Cannabinoid CB2 Receptor and Its Endogenous Ligand 2Arachidonoylglycerol in Oxazolone-Induced Contact Dermatitis in Mice (full 2006)
http://www.jimmunol.org/content/177/12/8796.full
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Methods evaluating cannabinoid and endocannabinoid effects on gastrointestinal functions. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16506408 Human adipose tissue binds and metabolizes the endocannabinoids anandamide and 2arachidonoylglycerol. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16949718 Monoacylglycerol lipase inhibition by organophosphorus compounds leads to elevation of brain 2-arachidonoylglycerol and the associated hypomotility in mice. (abst 2006)
Biochemistry, pharmacology and physiology of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand. (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16678907 The endocannabinoid 2-AG protects the blood-brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines. (abst 2006)
The CB1 Cannabinoid Receptor Mediates Excitotoxicity-induced Neural Progenitor Proliferation and Neurogenesis (full - 2007) http://www.jbc.org/content/282/33/23892.full Endocannabinoids and the haematological system (full - 2007)
Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon (full - 2007)
Diverse roles of 2-arachidonoylglycerol in invasion of prostate carcinoma cells: Location, hydrolysis and 12-lipoxygenase metabolism (full 2007)
Opposing Actions of Endocannabinoids on Cholangiocarcinoma Growth : RECRUITMENT OF Fas AND Fas LIGAND TO LIPID RAFTS (full 2007)
http://www.jbc.org/content/282/17/13098.full
Pharmacological enhancement of the endocannabinoid system in the nucleus accumbens shell stimulates food intake and increases c-Fos expression in the hypothalamus. (full 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2042935/?tool=pubmed Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228252/?tool=pmcentrez Identification of Endocannabinoids and Related Compounds in Human Fat Cells (full - 2007) http://www.nature.com/oby/journal/v15/n4/full/oby2007100a.html Endocannabinoids block status epilepticus in cultured hippocampal neurons (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2617750/?tool=pmcentrez
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Chronologically overlapping occurrences of nicotine-induced anxiety- and depressionrelated behavioral symptoms: effects of anxiolytic and cannabinoid drugs (full - 2007)
2-AG + 2 new players = forecast for therapeutic advances.
(full 2007)
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6VRP-4RFCCVN4&_user=10&_coverDate=12%2F26%2F2007&_rdoc=1&_fmt=high&_orig=gateway&_origin=gateway& _sort=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=9ee f728e35c89b5764ef2d27c0cdffe9&searchtype=a
CB2 receptors in the brain: role in central immune function

(full - 2007) (full - 2007)
Opposing Actions of Endocannabinoids on Cholangiocarcinoma Growth

Endocannabinoids, cannabinoid receptors and inflammatory stress: an interview with Dr. Pl Pacher (interview - 2007)
http://www.jleukbio.org/cgi/content/full/82/6/1390?maxtoshow=&hits=80&RESULTFORMAT=&fulltext =cannabinoid&searchid=1&FIRSTINDEX=880&resourcetype=HWCIT
Interactions of cannabidiol with endocannabinoid signalling in hippocampal tissue. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17419758 The endocannabinoids anandamide and 2-arachidonoylglycerol inhibit cholinergic contractility in the human colon. (abst 2007)
The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling. (full - 2008) http://www.fasebj.org/cgi/content/full/22/1/285 Cannabinoids Inhibit HIV-1 Gp120-Mediated Insults in Brain Microvascular Endothelial Cells (full - 2008)
http://www.jimmunol.org/cgi/content/full/181/9/6406?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabinoid&searchid=1&FIRSTINDEX=160&resourcetype=HWCIT
Endocannabinoid 2-Arachidonoylglycerol Protects Neurons by Limiting COX-2 Elevation (full 2008) http://www.jbc.org/content/283/33/22601.full Activating Parabrachial Cannabinoid CB1 Receptors Selectively Stimulates Feeding of Palatable Foods in Rats (full - 2008)
http://www.jneurosci.org/cgi/content/full/28/39/9702?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabinoid&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
Cannabinoid receptors and the regulation of bone mass
(full - 2008)
13
Pharmacological Inhibition of CB1 Cannabinoid Receptor Protects Against DoxorubicinInduced Cardiotoxicity (full - 2008) http://content.onlinejacc.org/cgi/content/full/50/6/528 Endocannabinoid Dysregulation in the Pancreas and Adipose Tissue of Mice Fed With a High-fat Diet (full - 2008) http://www.nature.com/oby/journal/v16/n3/full/oby2007106a.html Endocannabinoids and the Control of Energy Homeostasis (full 2008)
http://www.jbc.org/content/283/48/33021.full?sid=931583b1-e797-43e0-8296-7fd75bb49403
The influence of mast cell mediators on migration of SW756 cervical carcinoma cells. (full 2008) http://www.jstage.jst.go.jp/article/jphs/106/2/106_208/_article Endocannabinoids and nutrition. (full 2008)
http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2826.2008.01687.x/pdf
Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon. (full 2008)
Mechanisms for Recycling and Biosynthesis of Endogenous Cannabinoids Anandamide and 2-Arachidonylglycerol (full - 2008)
Dysregulation of the endocannabinoid system in obesity.

(abst 2008) (news - 2008) (news - 2008)
Understanding the effects of endogenous cannabinoids
http://arstechnica.com/science/news/2008/11/understanding-the-effects-of-endogenous-cannabinoids.ars
Marijuana-Inspired Painkiller? New Chemical Pathway Discovered

Changes in the Endocannabinoid System May Give Insight into new and Effective Treatments for Cancer (full - 2009)
Endocannabinoids and Their Receptors as Targets for Obesity Therapy (full - 2009)
http://endo.endojournals.org/cgi/content/full/150/6/2531#top
Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19502530 Circulating endocannabinoid concentrations during orthostatic stress
www.ncbi.nlm.nih.gov/pubmed/19756829
(abst 2009)
The endocannabinoid 2-arachidonoylglycerol promotes sperm developement through activation of cannabinoid-2 receptors (abst 2009)
http://www.cannabis-med.org/index.php?tpl=cannabinoids&id=238&lng=en&red=cannabinoidslist
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Cannabinoid Receptors as Target for Treatment of Osteoporosis: A Tale of Two Therapies (full 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001217/?tool=pubmed Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients (full - 2010)
http://www.lipidworld.com/content/9/1/43
Cannabinoid-mediated inhibition of recurrent excitatory circuitry in the dentate gyrus in a mouse model of temporal lobe epilepsy. (full 2010)
Endogenous cannabinoid signaling is essential for stress adaptation

(full - 2010)
Endocannabinoid signalling: has it got rhythm?
(full 2010)
The endocannabinoid 2-arachidonoyl-glycerol controls odor sensitivity in larvae of Xenopus laevis. (full 2010) http://www.jneurosci.org/content/30/26/8965.long The endocannabinoid system as a target for the treatment of neurodegenerative disease (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931550/?tool=pubmed The endocannabinoid 2-arachidonoylglycerol reduces lesion expansion and white matter damage after spinal cord injury. (abst - 2010)
The Multiplicity of Action of Cannabinoids: Implications for Treating Neurodegeneration. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20875047 Painkilling System in Brain: Too Much of a Good Thing?
(news - 2010)
Anti-proliferative Effect of a Putative Endocannabinoid, 2-Arachidonylglyceryl Ether in Prostate Carcinoma Cells (full 2011)
The endocannabinoid system and cancer: therapeutic implication

(full 2011)
Pharmacological exploitation of the endocannabinoid system: new perspectives for the treatment of depression and anxiety disorders? (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20512266/abstract/%5BPharmacological_exploitat ion_of_the_endocannabinoid_system:_new_perspectives_for_the_treatment_of_depression_and_anxiety_d isorders%5D_
15
Circulating and hepatic endocannabinoids and endocannabinoid-related molecules in patients with cirrhosis. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/19840245 Mutations in ABHD12 cause the neurodegenerative disease PHARC: An inborn error of endocannabinoid metabolism. (full 2011)
Krill oil significantly decreases 2-arachidonoylglycerol plasma levels in obese subjects. (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048484/?tool=pubmed The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2arachidonoylglycerol signalling through cannabinoid receptors (full 2011)
Dual inhibition of alpha/beta hydrolase domain 6 and fatty acid amide hydrolase increases endocannabinoid levels in neurons. (full 2011)
http://www.jbc.org/content/early/2011/06/10/jbc.M110.202853.long
Protective Role of Cannabinoid Receptor Type 2 in a Mouse Model of Diabetic Nephropathy. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21810593 The Endogenous Cannabinoid 2-Arachidonoylglycerol Is Intravenously SelfAdministered by Squirrel Monkeys (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21562266/abstract/The_Endogenous_Cannabinoid _2_Arachidonoylglycerol_Is_Intravenously_Self_Administered_by_Squirrel_Monkeys_
Increasing endogenous 2-arachidonoylglycerol levels counteracts colitis and related systemic inflammation. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21551239/abstract/Increasing_endogenous_2_arac hidonoylglycerol_levels_counteracts_colitis_and_related_systemic_inflammation_
Administration of 2-arachidonoylglycerol ameliorates both acute and chronic Experimental Autoimmune Encephalomyelitis (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21406188/abstract/Administration_of_2_arachidon oylglycerol_ameliorates_both_acute_and_chronic_Experimental_Autoimmune_Encephalomyelitis_
Endocannabinoid 2-arachidonoylglycerol protects neurons against -amyloid insults. (abst 2011)

http://www.unboundmedicine.com/medline/ebm/record/21256197/abstract/Endocannabinoid_2_arachidono ylglycerol_protects_neurons_against_%CE%B2_amyloid_insults_
Alteration of the Endocannabinoid System In Mouse Brain During Prion Disease. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21195746/abstract/Alteration_of_the_Endocannabi noid_System_In_Mouse_Brain_During_Prion_Disease_
Cannabinoid receptor 2 positions and retains marginal zone B cells within the splenic marginal zone. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21875957
16
The major central endocannabinoid directly acts at GABA(A) receptors.

(abst 2011)
2-Arachidonoylglycerol (2-AG) Induces Corneal Epithelial Cell Migration via Cannabinoid CB1 Receptors (abst 2011)
http://abstracts.iovs.org/cgi/content/abstract/52/6/1995?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype=HWCIT
Fish oil promotes survival and protects against cognitive decline in severely undernourished mice by normalizing satiety signals. (abst 2011)
Increment of hypothalamic 2-arachidonoylglycerol induces the preference for a high-fat diet via activation of cannabinoid 1 receptors (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/20817042/abstract/Increment_of_hypothalamic_2_ arachidonoylglycerol_induces_the_preference_for_a_high_fat_diet_via_activation_of_cannabinoid_1_rece ptors_
Endogenously generated 2-arachidonoylglycerol plays an inhibitory role in bombesininduced activation of central adrenomedullary outflow in rats. (abst 2011)
Endocannabinoid CB1 receptors modulate visual output from the thalamus. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21773721 Omega-3 N-acylethanolamines are endogenously synthesised from omega-3 fatty acids in different human prostate and breast cancer cell lines. (abst 2011)
Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21145341/abstract/Inhibition_of_endocannabinoid _catabolic_enzymes_elicits_anxiolytic_like_effects_in_the_marble_burying_assay_
New metabolic pathway for controlling brain inflammation
(news 2011)
http://www.news-medical.net/news/20111021/New-metabolic-pathway-for-controlling-braininflammation.aspx
Cannabinoid Receptor Type 1 (CB1) Activation Inhibits Small GTPase RhoA Activity and Regulates Motility of Prostate Carcinoma Cells. (abst 2012)
2-AGE/ 2-ARACHIDONYL GLYCERYL ETHER/ NOLADIN ETHER

endocannabinoid, CB 1 & 2 agonist
2-Arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor (full - 2001) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC31108/
17
Anandamide and noladin ether prevent neurotoxicity of the human amyloid-beta peptide. (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/12384227 Synthesis, in vitro evaluation, and intraocular pressure effects of water-soluble prodrugs of endocannabinoid noladin ether. (abst 2003)
The endocannabinoid noladin ether acts as a full agonist at human CB2 cannabinoid receptors. (full 2005) http://jpet.aspetjournals.org/content/314/2/868.long Effects of the endocannabinoid noladin ether on body weight, food consumption, locomotor activity, and cognitive index in mice. (abst 2005)
Noladin ether acts on trabecular meshwork cannabinoid (CB1) receptors to enhance aqueous humor outflow facility. (full 2006) http://www.iovs.org/content/47/5/1999.long 2-Arachidonylglyceryl ether and abnormal cannabidiol-induced vascular smooth muscle relaxation in rabbit pulmonary arteries via receptor-pertussis toxin sensitive G proteinsERK1/2 signaling. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17292352 Alterations in the hippocampal endocannabinoid system in diet-induced obese mice. (full 2010) http://www.jneurosci.org/content/30/18/6273.long Biosynthesis and degradation of the endocannabinoid 2-arachidonoylglycerol. (full 2011) http://onlinelibrary.wiley.com/doi/10.1002/biof.131/full Anti-proliferative Effect of a Putative Endocannabinoid, 2-Arachidonylglyceryl Ether in Prostate Carcinoma Cells (full 2011)
AGING /USE BY SENIORS Changes in cannabinoid receptor binding and mRNA levels in several brain regions of aged rats (full - 1998) http://www.ncbi.nlm.nih.gov/pubmed/9748581
18
The Peripheral Cannabinoid Receptor CB2 and CD40 Are Novel Biological Markers That Predict Outcome in Diffuse Large B-Cell Lymphoma of Elderly Patients. (abst - 2004)
http://abstracts.hematologylibrary.org/cgi/content/abstract/104/11/3256?maxtoshow=&hits=80&RESULTF ORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=800&resourcetype=HWCIT
Using Marijuana in Adulthood: the Experience of a Sample of Users in Oklahoma City. (abst 2005)
http://medical-journals.healia.com/doc/16537332/Using-marijuana-in-adulthood-the-experience-of-asample-of-users-in-Oklahoma-City
Pass the Doobie, pops
(news - 2005)
http://www.thefreelibrary.com/Pass+the+doobie%2c+pops.-a0131273013
Projecting drug use among aging baby boomers in 2020. (abst 2006)
Inflammation and aging: can endocannabinoids help?
(full - 2008)
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2408719&tool=pmcentrez
Cannabinoid receptor stimulation is anti-inflammatory and improves memory in old rats (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586121/?tool=pmcentrez Cannabinoids Attenuate the Effects of Aging Upon Neuroinflammation and Neurogenesis. (abst - 2008)
http://www.cannabisscience.com/research-a-development/anti-aging.html
CN BC: Expert Testifies Cannabis Helps Slow Aging (news - 2008)

http://www.mapinc.org/drugnews/v08/n458/a05.html
Could Marijuana Substance Help Prevent Or Delay Memory Impairment In The Aging Brain? (news - 2008) http://www.sciencedaily.com/releases/2008/11/081119120141.htm Marijuana may be good for the aging brain (news - 2008)
http://www.news-medical.net/news/2008/11/19/43212.aspx
Cannabinoid agonist WIN-55,212-2 partially restores neurogenesis in the aged rat brain (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011092/?tool=pubmed The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/21069097 The Management of Chronic Pruritus in the Elderly (full 2010)
http://www.skintherapyletter.com/2010/15.8/2.html
Deficiency of CB2 cannabinoid receptor in mice improves insulin sensitivity but increases food intake and obesity with age. (abst 2010)
http://www.springerlink.com/content/g037q1lh40l15161/
19
Older Adults' Pot Use Up
(news - 2010) (news - 2010)
http://www.mapinc.org/drugnews/v10/n138/a02.html?1189
Marijuana Use By Seniors Goes Up As Boomers Age

Pot Breaks the Age Barrier
(news - 2010)
Marijuana use among older adults in the U.S.A.: user characteristics, patterns of use, and implications for intervention (abst 2011)
http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=8259427&fulltextType=RA&f ileId=S1041610210002176
Early onset of aging-like changes is restricted to cognitive abilities and skin structure in Cnr1(-/-) mice. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/20724033 Role of CB1 cannabinoid receptors on GABAergic neurons in brain aging
(full 2011)
Gender-dependent increases with healthy aging of the human cerebral cannabinoid-type 1 receptor binding using [(18)F]MK-9470 PET. (abst 2011)
125 Year Old Woman Claimed Smoking Cannabis Everyday Was Her Secret to Long Life (news 2011)
http://www.hanf-info.ch/info/en/125-Year-Old-Woman-Claimed-Smoking.html
Endocannabinoid Signaling In Dietary Restriction And Lifespan Extension (news 2011) http://www.medicalnewstoday.com/releases/225007.php Bodyguard for the Brain: Researchers Identify Mechanism That Seems to Protect Brain from Aging (news 2011) http://www.sciencedaily.com/releases/2011/07/110712093856.htm Pot smoking not tied to middle-age mental decline (news 2012)
http://www.mnn.com/health/fitness-well-being/stories/pot-smoking-not-tied-to-middle-age-mental-decline
AIDS see HIV
20
AJULEMIC ACID/ IP-751/ HU-239 - synthetic analog of 8-THC-11-oic acid The Role of Cannabis and Cannabinoids in Pain Management
http://www.humanhemphealth.ca/Russo-AAPM_chapter.pdf
(full 2002) (news - 2002)
Marijuana-Derived Compound Targets Pain, Inflammation

Ajulemic Acid (IP-751): Synthesis, Proof of Principle, Toxicity Studies, and Clinical Trials (full - 2004) http://www.aapsj.org/view.asp?art=aapsj070115 Ajulemic acid: A novel cannabinoid produces analgesia without a high
http://www.ncbi.nlm.nih.gov/pubmed/15240185?dopt=Abstract
(abst - 2004)
Ajulemic acid (IP-751): Synthesis, proof of principle, toxicity studies, and clinical trials (full - 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751505/?tool=pubmed Marijuana-Derived Drug Suppresses Bladder Overactivity And Irritation In Animal Models (news - 2005)
http://www.sciencedaily.com/releases/2005/09/050906080225.htmhttp://www.sciencedaily.com/releases/2 005/09/050906080225.htm
Cannabimimetic Properties of Ajulemic Acid
(full - 2006) (news - 2006)
Marijuana-Derived Drug Suppresses Bladder Pain In Animal Models

Cannabimimetic Properties of Ajulemic Acid

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633725/
(full - 2007)
In humans, ajulemic acid has a more favorable side-effect profile than THC for the treatment of chronic neuropathic pain (full - 2007)
Letter: Preclinical assessment of abuse liability of ajulemic acid

(letter - 2007)
Suppression of fibroblast metalloproteinases by ajulemic acid, a nonpsychoactive cannabinoid acid. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/16927387 Effects of IP-751, ajulemic acid, on bladder overactivity induced by bladder irritation in rats. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17656248 Ajulemic acid, a nonpsychoactive cannabinoid acid, suppresses osteoclastogenesis in mononuclear precursor cells and induces apoptosis in mature osteoclast-like cells. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/17786950
21
Suppression of human macrophage interleukin-6 by a nonpsychoactive cannabinoid acid. (abst - 2008) http://www.ncbi.nlm.nih.gov/sites/pubmed Cannabinoids, Endocannabinoids, and Related Analogs in Inflammation
(full - 2009)
Cannabinoids as novel anti-inflammatory drugs.
(full - 2009)
Ajulemic acid, a synthetic cannabinoid, increases formation of the endogenous proresolving and anti-inflammatory eicosanoid, lipoxin A4 (full - 2009)
http://www.fasebj.org/cgi/content/full/23/5/1503?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=c annabis&searchid=1&FIRSTINDEX=2400&resourcetype=HWCIT
ALCOHOLISM /ALCOHOL Facts on Cannabis and Alcohol (article no date)

http://www.saferchoice.org/content/view/24/53/#longterm
Alcohol and marijuana: comparison of use and abuse in regular marijuana users. (abst 1984) http://www.ncbi.nlm.nih.gov/pubmed/6332109 Interaction of cannabidiol and alcohol in humans.
(abst 1979) (abst 1980)
Effect of Alcohol and Marihuana on Tobacco Smoking.

Concordant alcohol and marihuana use in women.

(abst 1986) (abst 1988)
Alcohol use, marihuana smoking, and sexual activity in women.

Marihuana attenuates the rise in plasma ethanol levels in human subjects. (abst 1992) http://www.ncbi.nlm.nih.gov/pubmed/1326277 Effects of Alcohol Pretreatment on Human Marijuana Self-administration. (abst 1994)
http://medical-journals.healia.com/doc/7862844/Effects-of-alcohol-pretreatment-on-human-marijuanaself-administration
Alcohol and marijuana: effects on epilepsy and use by patients with epilepsy. (abst 2001) http://www.ncbi.nlm.nih.gov/pubmed/11737161
22
Association of a CB1 cannabinoid receptor gene (CNR1) polymorphism with severe alcohol dependence. (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/11841893 Cannabis as a Substitute for Alcohol (full - 2003)
http://ccrmg.org/journal/03sum/substitutealcohol.html
Endocannabinoid signaling via cannabinoid receptor 1 is involved in ethanol preference and its age-dependent decline in mice (full - 2003)
Cannabinoid Cb1 Receptor Knockout Mice Exhibit Markedly Reduced Voluntary Alcohol Consumption and Lack Alcohol-induced Dopamine Release in the Nucleus Accumbens. (abst 2003)
http://medical-journals.healia.com/doc/12562514/Cannabinoid-CB1-receptor-knockout-mice-exhibitmarkedly-reduced-voluntary-alcohol-consumption-and-lack-alcohol-induced-dopamine-release-in-thenucleus-accumbens
Overeating, Alcohol and Sucrose Consumption Decrease in Cb1 Receptor Deleted Mice. (abst 2004)
http://medical-journals.healia.com/doc/12770700/Overeating-alcohol-and-sucrose-consumption-decreasein-CB1-receptor-deleted-mice
Comparison of Cannabidiol, Antioxidants, and Diuretics in Reversing Binge EthanolInduced Neurotoxicity (full - 2005) http://jpet.aspetjournals.org/content/314/2/780.full Ethanol Induces Higher Bec in Cb1 Cannabinoid Receptor Knockout Mice While Decreasing Ethanol Preference. (full 2005)
http://alcalc.oxfordjournals.org/content/40/1/54.long
Alcohol Consumption Moderates the Link Between Cannabis Use and Cannabis Dependence in an Internet Survey. (abst 2005)
http://psycnet.apa.org/journals/adb/19/2/212/
Role of cannabinoid receptors in alcohol abuse

http://www.medicalnewstoday.com/articles/30338.php
(news - 2005)
Effects of Alcohol and Combined Marijuana and Alcohol Use During Adolescence on Hippocampal Volume and Asymmetry (full - 2006)
In vivo effects of CB1 receptor ligands on lipid peroxidation and antioxidant defense systems in the rat brain of healthy and ethanol-treated rats. (full 2006)
23
Confirming alcohol-moderated links between cannabis use and dependence in a national sample (abst 2006) http://www.sciencedirect.com/science/article/pii/S0306460305002959 The endocannabinoid signaling system: a potential target for next-generation therapeutics for alcoholism (full - 2007) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1975858 Involvement of cannabinoid CB2 receptor in alcohol preference in mice and alcoholism in humans (abst 2007) http://pharmgkb.org/pmid/17189959 Report: Marijuana Less Harmful than Alcohol or Tobacco Cannabis reverses brain damage from alcohol (news - 2008)
http://www.jointogether.org/news/headlines/inthenews/2008/report-marijuana-less.html
(news - 2008) (full - 2009)
http://medicalcannabisawareness.myblogsite.com/entry36.html#body
Cannabis as a substitute for alcohol and other drugs.
Daily marijuana users with past alcohol problems increase alcohol consumption during marijuana abstinence. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19783385/full_citation/Daily_marijuana_users_wit h_past_alcohol_problems_increase_alcohol_consumption_during_marijuana_abstinence_
White Matter Integrity in Adolescents with Histories of Marijuana Use and Binge Drinking. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19631736/abstract/White_Matter_Integrity_in_Ad olescents_with_Histories_of_Marijuana_Use_and_Binge_Drinking_
Maternal Marijuana use not Associated with Psychotic Symptoms , but Alcohol is (news - 2009)
http://ohiopatientsnetwork.org/index.php?option=com_content&view=article&id=85:marijuana-notassociated-with-psychotic-symptoms-but-alcohol-is&catid=3:newsflash
Cannabis as a substitute for heavy alcohol usage?
(news - 2009)
http://www.news-medical.net/news/20091201/Cannabis-as-a-substitute-for-heavy-alcohol-usage.aspx
Influence of ethanol on cannabinoid pharmacokinetic parameters in chronic users (full - 2010) http://www.springerlink.com/content/511171841x1u1521/fulltext.html Learning and memory performances in adolescent users of alcohol and marijuana: interactive effects. (full 2010)
http://www.thefreelibrary.com/Learning+and+memory+performances+in+adolescent+users+of+alcohol+an d...-a0241277101
The Endocannabinoid System Tonically Regulates Inhibitory Transmission and Depresses the Effect of Ethanol in Central Amygdala (abst - 2010)
http://www.nature.com/npp/journal/v35/n9/abs/npp201070a.html
24
11-nor-Delta9-tetrahydrocannabinol-9-carboxylic acid ethyl ester (THC-COOEt): unsuccessful search for a marker of combined cannabis and alcohol consumption. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20074877/abstract/11_nor_Delta9_tetrahydrocanna binol_9_carboxylic_acid_ethyl_ester__THC_COOEt_:_unsuccessful_search_for_a_marker_of_combined_ cannabis_and_alcohol_consumption_
Role of the endocannabinoid system in alcoholic liver disease.

(abst 2010)
The effects of cannabis and alcohol on simulated arterial driving: Influences of driving experience and task demand. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20380913/abstract/The_effects_of_cannabis_and_a lcohol_on_simulated_arterial_driving:_Influences_of_driving_experience_and_task_demand_
Study shows direct cellular interaction between endocannabinoids and alcohol in the brain (news - 2010)
http://www.news-medical.net/news/20100513/Study-shows-direct-cellular-interaction-betweenendocannabinoids-and-alcohol-in-the-brain.aspx
Marijuana To Control Alcohol Abuse
(news - 2010)
http://psychcentral.com/news/2009/12/01/marijuana-to-control-alcohol-abuse/9863.html
Marijuana May Offset Alcohol-Induced Cognitive Impairment Among Teens (news 2010) http://www.norml.org/index.cfm?Group_ID=8378 Study Overturns Decade-Old Findings in Neurobiology: Research Suggests Potential Target for Drugs to Combat Alcohol Addiction (news - 2010)
Combined effects of acute, very-low-dose ethanol and delta(9)-tetrahydrocannabinol in healthy human volunteers (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21110996 Cannabinoid CB2 receptors protect against alcoholic liver disease by regulating kupffer cell polarization in mice. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21735467 Pharmacological activation/inhibition of the cannabinoid system affects alcohol withdrawal-induced neuronal hypersensitivity to excitotoxic insults. (abst 2011)
Popular intoxicants: what lessons can be learned from the last 40 years of alcohol and cannabis regulation? (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21926420 Racial differences in trajectories of heavy drinking and regular marijuana use from ages 13 to 24 among African-American and White males. (abst 2011)
Some features of teenage beer alcoholism combined with hashish addiction (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21322145
25
Influence of ethanol on cannabinoid pharmacokinetic parameters in chronic users. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21116612 Rural adolescent alcohol, tobacco, and illicit drug use: a comparison of students in victoria, australia, and washington state, United States. (abst 2011)
http://marijuana.researchtoday.net/archive/8/10/4782.htm
Latest Studies Imply That Cannabinoids Are Protective Against Alcohol-Induced Brain Damage (news 2011) http://networkedblogs.com/mFuuX Why Medical Marijuana Laws Reduce Traffic Deaths (news - 2011)
http://healthland.time.com/2011/12/02/why-medical-marijuana-laws-reduce-traffic-deaths/
Upregulation of cannabinoid type 1 receptors in dopamine D2 receptor knockout mice is reversed by chronic forced ethanol consumption. (full 2012)
Tolerance to cannabinoid-induced behaviors in mice treated chronically with ethanol. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/21701813
ALLERGIES AND CANNABIS Marijuana smoking and fungal sensitization.

(abst - 1983)
Histamine induced responses are attenuated by a cannabinoid receptor agonist in human skin. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12835895 Pot Chemical May Curb Inflammation Cannabis helps treat allergic reactions (news 2007) (news - 2007)
http://www.webmd.com/allergies/news/20070607/pot-chemical-may-curb-inflammation
http://www.safeaccessnow.org/article.php?id=4768
Constituents Of Hashish And Marijuana May Help To Fight Inflammation And Allergies (news - 2007) http://www.sciencedaily.com/releases/2007/06/070607171120.htm Marijuana Might Help Cure Allergic Contact Dermatitis (a.k.a. Poison Ivy) (news - 2007) http://www.healthcentral.com/skin-cancer/c/83/12569/cure-aka-ivy/1/ Cannabis for allergic contact dermatitis (news - 2007)
26
Constituents Of Hashish And Marijuana May Help To Fight Inflammation And Allergies (news - 2007) http://www.sciencedaily.com/releases/2007/06/070607171120.htm Cannabis can reduce Allergic Skin Reactions, latest research shows (news - 2007)
http://www.healthjockey.com/2007/06/08/cannabis-can-reduce-allergic-skin-reactions-latest-researchshows/
Allergic Skin Disease Could Be Treated With Substance Found In Cannabis (news 2007) http://www.medicalnewstoday.com/releases/79889.php Attenuation of Allergic Contact Dermatitis Through the Endocannabinoid System (full - 2008)
http://pediatrics.aappublications.org/cgi/reprint/122/Supplement_4/S200a?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1120 &resourcetype=HWCIT
Hemp: A replacement for common food allergens?
(news - 2009)
http://www.examiner.com/x-20151-Manchester-Gluten-Free-Examiner~y2009m8d25-Hemp--Areplacement-for-common-food-allergens
Cannabidiol attenuates delayed-type hypersensitivity reactions via suppressing T-cell and macrophage reactivity. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/21042286 Beneficial effects of cannabinoids (CB) in a murine model of allergen-induced airway inflammation: Role of CB(1)/CB(2) receptors. (abst - 2010)
http://www.unboundmedicine.com/medline/ebm/record/21056512/abstract/Beneficial_effects_of_cannabin oids__CB__in_a_murine_model_of_allergen_induced_airway_inflammation:_Role_of_CB_1_/CB_2__rec eptors_
Protective role of palmitoylethanolamide in contact allergic dermatitis.

(abst 2010)
The cannabinoid receptor agonist WIN 55,212-2 inhibits antigen-induced plasma extravasation in guinea pig airways. (abst 2010)
Effects of palmitoylethanolamide on the cutaneous allergic inflammatory response in Ascaris hypersensitive Beagle dogs. (abst 2011)
ALLERGIES TO CANNABIS Allergy to Marihuana (abst - 1971)

http://www.annals.org/content/75/4/571.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=ca nnabis&searchid=1&FIRSTINDEX=1920&resourcetype=HWCIT
27
Occupational immediate type allergy to hemp pollen and hashish

(abst 1980)
Allergic Skin Test Reactivity to Marijuana in the Southwest Allergenic properties of naturally occurring cannabinoids.
(full - 1983) (abst - 1983) (abst - 2000) (full - 2007) (abst 2007)
Cannabis (hemp) positive skin tests and respiratory symptoms

Allergic rhinoconjunctivitis caused by Cannabis sativa pollen

http://www.jiaci.org/issues/vol18issue1/13-17.pdf
Cannabaceae Pollen in the Atmosphere of Brianza, Northen Italy.
http://medical-journals.healia.com/doc/17375735/Cannabaceae-pollen-in-the-atmosphere-of-BrianzaNorthen-Italy
Sensitization and Allergy to Cannabis sativa Leaves in a Population of Tomato Sensitized Patients. (abst - 2008) http://marijuana.researchtoday.net/archive/5/2/1629.htm Allergic hypersensitivity to cannabis in patients with allergy and illicit drug users. (full 2011) http://www.elsevier.es/sites/default/files/elsevier/eop/S0301-0546%2810%2900287-9.pdf IgE-Mediated Hypersensitivity Reactions to Cannabis in Laboratory Personnel. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21832832
ALS / AMYOTROPHIC LATERAL SCLEROSIS Marijuana in the management of amyotrophic lateral sclerosis (abst - 2001)
http://ajh.sagepub.com/cgi/content/abstract/18/4/264?maxtoshow=&hits=80&RESULTFORMAT=&fulltex t=cannabis&searchid=1&FIRSTINDEX=1200&resourcetype=HWCIT
Survey of cannabis use in patients with amyotrophic lateral sclerosis.
(abst - 2004)
http://ajh.sagepub.com/cgi/content/abstract/21/2/95?maxtoshow=&hits=80&RESULTFORMAT=&fulltext =cannabinoid&searchid=1&FIRSTINDEX=2000&resourcetype=HWCIT
Delayed disease progression in ALS mice by treatment with a cannabinoid. (abst - 2004)
Cannabis' Potential Exciting Researchers in Treatment of ALS, Parkinson's Disease URB597 (news - 2004)
http://www.illinoisnorml.org/index2.php?option=com_content&do_pdf=1&id=104
28
Cannabis Relieves Lou Gehrigs Symptoms - New Study

http://www.rense.com/general51/lou.htm
(news - 2004)
Cannabinol delays symptom onset in SOD1 (G93A) transgenic mice without affecting survival. (abst - 2005)
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=1618356 0
Increasing cannabinoid levels by pharmacological and genetic manipulation delay disease progression in SOD1 mice (full - 2006) http://www.fasebj.org/cgi/content/full/20/7/1003 AM1241, a cannabinoid CB2 receptor selective compound, delays disease progression in a mouse model of amyotrophic lateral sclerosis. (abst - 2006)
The CB2 cannabinoid agonist AM-1241 prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onset (full - 2007)
The endocannabinoid system in targeting inflammatory neurodegenerative diseases (full - 2007)

http://medicalcannabis.com/images/pdf09/indications/neurodegenerative/centonze_et_al_2007_inflammato ry_neuro.pdf
Cannabinoids and neuroprotection in motor-related disorders.

(abst - 2007)
The (Endo)Cannabinoid System in Multiple Sclerosis and Amyotrophic Lateral Sclerosis (abst 2007)
http://medical-journals.healia.com/doc/17678961/The-endocannabinoid-system-in-multiple-sclerosis-andamyotrophic-lateral-sclerosis
The endocannabinoid system in amyotrophic lateral sclerosis.

(abst 2008)
Altered presymptomatic AMPA and cannabinoid receptor trafficking in motor neurons of ALS model mice: implications for excitotoxicity. (abst - 2008)
Role of CB2 receptors in neuroprotective effects of cannabinoids.

(abst - 2008)
Emerging Role of the CB2 Cannabinoid Receptor in Immune Regulation and Therapeutic Prospects (full - 2009)
Cannabinoids as Therapeutic Agents for Ablating Neuroinflammatory Disease (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750822/?tool=pmcentrez
29
Cannabinoids and neurodegenerative diseases.

(abst - 2009)
Cannabis and Amyotrophic Lateral Sclerosis: Hypothetical and Practical Applications, and a Call for Clinical Trials. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20439484 The endocannabinoid system in the inflammatory and neurodegenerative processes of multiple sclerosis and of amyotrophic lateral sclerosis. (abst - 2010)
Abnormal sensitivity of cannabinoid CB1 receptors in the striatum of mice with experimental amyotrophic lateral sclerosis. (abst 2010)
The endocannabinoid system in gp120-mediated insults and HIV-associated dementia. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20353779 Tetrahydrocannabinol (THC) for cramps in amyotrophic lateral sclerosis: a randomised, double-blind crossover trial. (abst 2010)
http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=291
Marijuana May Extend Life Expectancy Of Lou Gehrig's Disease Patients, Study Says (news - 2010) http://www.norml.org/index.cfm?Group_ID=8191
ALZHEIMER'S DISEASE Marijuana reduces memory impairment (news - no date)

http://www.healthnewstrack.com/health-news-811.html
Effects of dronabinol on anorexia and disturbed behavior in patients with Alzheimer's disease. (abst - 1997) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=59 Anandamide and noladin ether prevent neurotoxicity of the human amyloid-beta peptide. (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/12384227 US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants
http://www.patentstorm.us/patents/6630507.html
(full - 2003)
Cannabinoid CB2 Receptors and Fatty Acid Amide Hydrolase Are Selectively Overexpressed in Neuritic Plaque-Associated Glia in Alzheimer's Disease Brains (full 2003)
http://www.jneurosci.org/content/23/35/11136.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext= cannabinoid&searchid=1&FIRSTINDEX=80&resourcetype=HWCIT
30
Safety and efficacy of Dronabinol in the treatment of agitation in patients with Alzheimers disease with anorexia (abst - 2003)
Open-label study of Dronabinol in the treatment of refractory agitation in Alzheimers disease : a pilot study (abst - 2003)
Neuroprotective effect of cannabidiol, a non-psychoactive component from Cannabis sativa, on -amyloid-induced toxicity in PC12 cells (full - 2004)
http://www3.interscience.wiley.com/cgi-bin/fulltext/118757302/HTMLSTART
Early age-related cognitive impairment in mice lacking cannabinoid CB1 receptors. (full 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266095/?tool=pubmed Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation (full - 2005) http://www.jneuroinflammation.com/content/2/1/29 Prevention of Alzheimer's Disease Pathology by Cannabinoids: Neuroprotection Mediated by Blockade of Microglial Activation (full - 2005)
http://www.jneurosci.org/cgi/content/full/25/8/1904
Avoidance of Abeta[(25-35)] / (H(2)O(2)) -induced apoptosis in lymphocytes by the cannabinoid agonists CP55,940 and JWH-015 via receptor-independent and PI3Kdependent mechanisms: role of NF-kappaB and p53. (abst 2005)
Phosphorylated amyloid-beta: the toxic intermediate in alzheimer's disease neurodegeneration. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/15709490 Cannabinoid control of motor function at the basal ganglia.
(abst 2005) (news - 2005)
Marijuana Ingredient May Stall Decline From Alzheimer's

Marijuana Slows Alzheimer's Decline Marijuana May Block Alzheimer's
(news - 2005)
(news - 2005) (news - 2005) (news - 2005)
http://news.bbc.co.uk/2/hi/health/4286435.stm
Marijuana Ingredient May Help Alzheimer's
http://www.webmd.com/alzheimers/news/20050223/marijuana-ingredient-may-help-alzheimers
Cannabinoids reduce the progression of Alzheimer's disease in animals
31
Pass the Doobie, pops
(news - 2005)
http://www.thefreelibrary.com/Pass+the+doobie%2c+pops.-a0131273013
The Cannabinoid CB2 Receptor as a Target for Inflammation-Dependent Neurodegeneration (full - 2006)
A Molecular Link between the Active Component of Marijuana and Alzheimers Disease Pathology (full - 2006) http://www.ukcia.org/research/AlzheimersDiseasePathology.pdf Delta-9-tetrahydrocannabinol for nighttime agitation in severe dementia (full - 2006) http://science.iowamedicalmarijuana.org/pdfs/neuro/Walther%202006.pdf Endocannabinoids and beta-amyloid-induced neurotoxicity in vivo: effect of pharmacological elevation of endocannabinoid levels. (abst 2006)
Cannabidiol inhibits inducible nitric oxide synthase protein expression and nitric oxide production in beta-amyloid stimulated PC12 neurons through p38 MAP kinase and NFkappaB involvement. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16490313 The marijuana component cannabidiol inhibits beta-amyloid-induced tau protein hyperphosphorylation through Wnt/beta-catenin pathway rescue in PC12 cells. (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16389547 CB1 receptor selective activation inhibits beta-amyloid-induced iNOS protein expression in C6 cells and subsequently blunts tau protein hyperphosphorylation in co-cultured neurons. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16837132 Marijuana Compound Efficient Against Alzheimer's Disease (news 2006)
http://news.softpedia.com/news/Marijuana-Compound-Efficient-against-Alzheimer-s-Disease-37410.shtml
THC inhibits primary marker of Alzheimer's disease
(news - 2006)
Marijuana's Active Ingredient May Slow Progression Of Alzheimer's Disease (news - 2006) http://www.sciencedaily.com/releases/2006/10/061009031544.htm Marijuana may help stave off Alzheimers
http://www.msnbc.msn.com/id/15145917/
(news - 2006)
Marijuana May Slow Alzheimer's
(news - 2006) (news - 2006)
http://www.webmd.com/alzheimers/news/20061006/marijuana-may-slow-alzheimers
Pot-Like Compound May Slow Alzheimer's
http://www.webmd.com/alzheimers/news/20061019/pot-like-compound-may-slow-alzheimers
32
Latest Buzz: Marijuana May Slow Progression Of Alzheimer's Disease

(news - 2006)
Alzheimer's disease; taking the edge off with cannabinoids?
(full - 2007)
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=17828287
Cannabidiol in vivo blunts -amyloid induced neuroinflammation by suppressing IL-1 and iNOS expression (full - 2007)
Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence. (full - 2007)
Anti-inflammatory property of the cannabinoid agonist WIN-55212-2 in a rodent model of chronic brain inflammation (full - 2007)

Cannabinoid CB2 receptors in human brain inflammation

(full - 2008)
Cannabinoid receptor stimulation is anti-inflammatory and improves memory in old rats (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586121/?tool=pmcentrez Cannabinoids as Therapeutic Agents for Ablating Neuroinflammatory Disease (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750822/?tool=pmcentrez Inflammation and aging: can endocannabinoids help? (full - 2008)
Amyloid precursor protein 96-110 and beta-amyloid 1-42 elicit developmental anomalies in sea urchin embryos and larvae that are alleviated by neurotransmitter analogs for acetylcholine, serotonin and cannabinoids. (full 2008)

(abst - 2008)
The role of the endocannabinoid system in Alzheimer's disease: facts and hypotheses. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18781980 Scientists are High on Idea that Cannabis Reduces Memory Impairment
http://www.physorg.com/news146320102.html
(news - 2008)
33
Israeli Research Shows Cannabidiol May Slow Alzheimer's Disease

http://www.israelnationalnews.com/News/News.aspx/125564
(news - 2008)
Marijuana may be good for the aging brain
(news - 2008) (news - 2008)
Alzheimer's sufferers may benefit from cannabis compound

Cannabis 'could stop dementia in its tracks'
(news - 2008)
http://www.dailymail.co.uk/health/article-1087544/Cannabis-stop-dementia-tracks.html
Could Marijuana Substance Help Prevent Or Delay Memory Impairment In The Aging Brain? (news - 2008) http://www.sciencedaily.com/releases/2008/11/081119120141.htm Attacking Alzheimer's with Red Wine and Marijuana
http://www.alternet.org/story/110806/
(news - 2008)
Can cannabis offer hope for Alzheimer's?
(news - 2008) (news - 2008) (news - 2008)
http://findarticles.com/p/articles/mi_8002/is_2008_March_11/ai_n38819766/?tag=content;col1
Cannabis-derived medicines may help Alzheimer's

Pot joins the fight against Alzheimer's, memory loss
http://www.scientificamerican.com/blog/60-second-science/post.cfm?id=pot-joins-the-fight-againstalzheim-2008-11-19
Emerging Role of the CB2 Cannabinoid Receptor in Immune Regulation and Therapeutic Prospects (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768535/?tool=pmcentrez Cannabidiol: a promising drug for neurodegenerative disorders?
(full - 2009)
The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages. (abst - 2009)
http://www.ncbi.nlm.nih.gov/pubmed/19505450?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPa nel.Pubmed_RVDocSum&ordinalpos=18
New neuron production can be increased in the hippocampus of aged rats following cannabinoid treatment (abst 2009)
http://www.scribd.com/doc/49274316/smokeWeedErryDay
Cannabinoid agonist WIN-55,212-2 partially restores neurogenesis in the aged rat brain (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011092/?tool=pubmed Cannabinoids and Dementia: A Review of Clinical and Preclinical Data
http://www.mdpi.com/1424-8247/3/8/2689/pdf
(full 2010)
34
The development of cannabinoid CBII receptor agonists for the treatment of central neuropathies. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20236042/abstract/The_development_of_cannabin oid_CBII_receptor_agonists_for_the_treatment_of_central_neuropathies_
Endocannabinoids Prevent -Amyloid-mediated Lysosomal Destabilization in Cultured Neurons (abst 2010) http://www.jbc.org/content/285/49/38543.abstract The endocannabinoid system in gp120-mediated insults and HIV-associated dementia. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20353779 The Multiplicity of Action of Cannabinoids: Implications for Treating Neurodegeneration. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20875047 Marijuana could prevent Alzheimer's (news - 2010)
http://www.thelantern.com/mobile/2.1345/marijuana-could-prevent-alzheimer-s-1.72932
Cannabidiol and other cannabinoids reduce microglial activation in vitro and in vivo: relevance to Alzheimers' disease (full 2011)
http://molpharm.aspetjournals.org/content/early/2011/02/24/mol.111.071290.long
Cannabidiol Reduces A-Induced Neuroinflammation and Promotes Hippocampal Neurogenesis through PPAR Involvement (full 2011)
Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21238581 An amyloid (42)-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer's disease (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21546126/abstract/An_amyloid_%CE%B2_42__d ependent_deficit_in_anandamide_mobilization_is_associated_with_cognitive_dysfunction_in_Alzheimer% 27s_disease_
Molecular reorganization of endocannabinoid signalling in Alzheimer's disease. (abst 2011)

http://www.unboundmedicine.com/medline/ebm/record/21459826/abstract/Molecular_reorganization_of_e ndocannabinoid_signalling_in_Alzheimer%27s_disease_
Palmitoylethanolamide counteracts reactive astrogliosis induced by beta-amyloid peptide. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21255263 The role of phytochemicals in the treatment and prevention of dementia. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21639405/abstract/The_role_of_phytochemicals_i n_the_treatment_and_prevention_of_dementia_
Early onset of aging-like changes is restricted to cognitive abilities and skin structure in Cnr1(-/-) mice. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/20724033
35
Intact cannabinoid CB1 receptors in the Alzheimer's disease cortex.

(abst 2011)
The effects of hempseed meal intake and linoleic acid on Drosophila models of neurodegenerative diseases and hypercholesterolemia. (abst 2011)
Endocannabinoid 2-arachidonoylglycerol protects neurons against -amyloid insults. (abst 2011)

http://www.unboundmedicine.com/medline/ebm/record/21256197/abstract/Endocannabinoid_2_arachidono ylglycerol_protects_neurons_against_%CE%B2_amyloid_insults_
(news 2011)
Protective effect of cannabinoid CB1 receptor activation against altered intrinsic repetitive firing properties induced by A neurotoxicity. (abst 2012)
Contrasting protective effects of cannabinoids against oxidative stress and amyloid- evoked neurotoxicity in vitro. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/22233683 Contrasting protective effects of cannabinoids against oxidative stress and amyloid- evoked neurotoxicity in vitro. (abst 2012 )
AM-251 synthetic, GPR 55 agonist, CB1 antagonist/ inverse agonist Inhibition of Rat C6 Glioma Cell Proliferation by Endogenous and Synthetic Cannabinoids. Relative Involvement of Cannabinoid and Vanilloid Receptors (full - 2001) http://jpet.aspetjournals.org/content/299/3/951.full Influence of the CB1 receptor antagonist, AM 251, on the regional haemodynamic effects of WIN-55212-2 or HU 210 in conscious rats (full - 2002)
CB1 cannabinoid receptor antagonism promotes remodeling and cannabinoid treatment prevents endothelial dysfunction and hypotension in rats with myocardial infarction (full - 2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573770/?tool=pmcentrez Vasodilator actions of abnormal-cannabidiol in rat isolated small mesenteric artery (full - 2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573773/?tool=pmcentrez
36
Cannabinoid CB2 receptor activation reduces mouse myocardial ischemia-reperfusion injury: involvement of cytokine/chemokines and PMN (full - 2003)
http://www.jleukbio.org/cgi/content/full/75/3/453?maxtoshow=&hits=80&RESULTFORMAT=&fulltext= cannabinoid&searchid=1&FIRSTINDEX=320&resourcetype=HWCIT
Effects of cannabinoid receptor-2 activation on accelerated gastrointestinal transit in lipopolysaccharide-treated rats (full - 2004)
Up-Regulation of Cyclooxygenase-2 Expression Is Involved in R(_)-MethanandamideInduced Apoptotic Death of Human Neuroglioma Cells (full - 2004)
http://science.iowamedicalmarijuana.org/pdfs/cancer/Hinz%202004.pdf
The cannabinoid 1 receptor antagonist, AM251, prolongs the survival of rats with severe acute pancreatitis. (full - 2005) http://www.jstage.jst.go.jp/article/tjem/207/2/207_99/_article Cannabinoids augment the release of neuropeptide Y in the rat hypothalamus (abst 2005) http://www.sciencedirect.com/science/article/pii/S0028390805001668 Cannabinoid CB1 receptor antagonists cause status epilepticus-like activity in the hippocampal neuronal culture model of acquired epilepsy (full - 2006)
AM 251 produces sustained reductions in food intake and body weight that are resistant to tolerance and conditioned taste aversion (full - 2006)
Antinociceptive effect of cannabinoid agonist WIN 55,2122 in rats with a spinal cord injury (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1861843/?tool=pmcentrez Inhibition of Salivary Secretion by Activation of Cannabinoid Receptors (full - 2006)
http://ebm.rsmjournals.com/cgi/content/full/231/8/1421?maxtoshow=&hits=80&RESULTFORMAT=&full text=cannabinoid&searchid=1&FIRSTINDEX=880&resourcetype=HWCIT
Cannabinoid derivatives induce cell death in pancreatic MIA PaCa-2 cells via a receptorindependent mechanism. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16500647 Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190006/?tool=pmcentrez CANNABINOID-INDUCED HYPERPHAGIA: CORRELATION WITH INHIBITION OF PROOPIOMELANOCORTIN NEURONS? (full - 2007)
Cannabinoid action in the olfactory epithelium
(full - 2007)
37
Cannabinoids Inhibit HIV-1 Gp120-Mediated Insults in Brain Microvascular Endothelial Cells (full - 2008)
Loss of cannabinoid receptor 1 accelerates intestinal tumor growth

(full - 2008)
Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats (full - 2008)
Activating Parabrachial Cannabinoid CB1 Receptors Selectively Stimulates Feeding of Palatable Foods in Rats (full - 2008)
Feeding induced by cannabinoids is mediated independently of the melanocortin system. (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386290/?tool=pubmed High concentrations of cannabinoids activate apoptosis in human U373MG glioma cells. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18615640 Synthetic and plant-derived cannabinoid receptor antagonists show hypophagic properties in fasted and non-fasted mice (full - 2009)
Endocannabinoids in the rat basolateral amygdala enhance memory consolidation and enable glucocorticoid modulation of memory (full - 2009)
Modulation of motor and sensory pathways of the peristaltic reflex by cannabinoids. (full 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739820/?tool=pubmed Endocannabinoids prevent lysosomal membrane destabilisation evoked by treatment with -amyloid in cultured rat cortical neurons (abst 2009)
http://www.physoc.org/custom2/publications/proceedings/archive/article.asp?ID=Proc%20Physiol%20Soc %2015C9
38

(abst - 2009)
Effects of the cannabinoid CB1 receptor antagonist AM 251 on the reinstatement of nicotine-conditioned place preference by drug priming in rats. (full - 2009)
Regulation of the Hypothalamic-Pituitary-Adrenal Axis Circadian Rhythm by Endocannabinoids Is Sexually Diergic (full - 2010)
Cannabinoids excite circadian clock neurons.
(full 2010)
Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis (full - 2010)
Spinal and peripheral analgesic effects of the CB cannabinoid receptor agonist AM1241 in two models of bone cancer-induced pain. (full - 2010)
Anandamide and AM251, via water, modulate food intake at central and peripheral level in fish. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/19800340 Pharmacological characterization of GPR55, a putative cannabinoid receptor. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20298715/abstract/Pharmacological_characterizati on_of_GPR55_a_putative_cannabinoid_receptor_
Cannabidiol (CBD) as an Anti-Arrhythmic the Role of the CB1 Receptors (news 2010)
http://cannabisclinicians.org/2011/cannabidiol-cbd-as-an-anti-arrhythmic-the-role-of-the-cb1-receptors/
AM251, cannabinoids receptors ligand, improves recognition memory in rats. (full 2011) http://www.if-pan.krakow.pl/pjp/pdf/2011/3_670.pdf Cannabinoids prevent the development of behavioral and endocrine alterations in a rat model of intense stress. (full 2011)
39
-Tocopherol and -tocopheryl phosphate interact with the cannabinoid system in the rodent hippocampus. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21843633 Cannabidiol as an anti-arrhythmic, the role of the CB1 receptors. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/22116907/abstract/17_Cannabidiol_as_an_anti_arr hythmic_the_role_of_the_CB1_receptors_
CB(1) -independent mechanisms of (9) -THCV, AM251 and SR141716 (rimonabant). (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21740450 Endocannabinoid CB1 receptors modulate visual output from the thalamus. (abst 2011)
The effects of cannabinoid drugs on abnormal involuntary movements in dyskinetic and non-dyskinetic 6-hydroxydopamine lesioned rats. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/20888328/abstract/The_effects_of_cannabinoid_dr ugs_on_abnormal_involuntary_movements_in_dyskinetic_and_non_dyskinetic_6_hydroxydopamine_lesio ned_rats_
Pot and Pumpkin Pie: Endocannabinoid System Enhanced by Vitamin E
(news 2011)
http://www.examiner.com/medical-marijuana-in-philadelphia/pot-and-pumpkin-pie-endocannabinoidsystem-enhanced-by-vitamin-e
Opposing Roles for Cannabinoid Receptor Type-1 (CB(1)) and Transient Receptor Potential Vanilloid Type-1 Channel (TRPV1) on the Modulation of Panic-Like Responses in Rats. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/21937980 The cannabinoid receptor CB inverse agonist AM251 potentiates the anxiogenic activity of urocortin I in the basolateral amygdala. (abst 2012)
AM- 281 - synthetic, CB1 antagonist and inverse agonist Design and Synthesis of the CB1 Selective Cannabinoid Antagonist AM281: A Potential Human SPECT Ligand (full 1999) http://www.aapsj.org/view.asp?art=ps010204 Effects of AM281, a cannabinoid antagonist, on systemic haemodynamics, internal carotid artery blood flow and mortality in septic shock in rats (full 2005)
http://bja.oxfordjournals.org/content/94/5/563.full
40
CARDIOVASCULAR Effects of AM281, a cannabinoid antagonist, on systemic haemodynamics, internal carotid artery blood flow and mortality in septic shock in rats (abst 2005) http://academic.research.microsoft.com/Paper/11905213 Effects of AM281, a cannabinoid antagonist, on circulatory deterioration and cytokine production in an endotoxin shock model: comparison with norepinephrine. (abst 2006)
Expression of cannabinoid CB1 receptors by vagal afferent neurons: kinetics and role in influencing neurochemical phenotype (full 2010)
http://ajpgi.physiology.org/content/299/1/G63.full?sid=fc6948f0-78cf-405c-981b-afaa05ee417c
Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines. (full 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930808/?tool=pubmed
AM-404 synthetic, CB1 agonist Synergistic Interactions between Cannabinoids and Environmental Stress in the Activation of the Central Amygdala (full - 2005)
Enhancing Cannabinoid Neurotransmission Augments the Extinction of Conditioned Fear (full - 2005) http://www.nature.com/npp/journal/v30/n3/full/1300655a.html Anxiolytic-like properties of the anandamide transport inhibitor AM404.
(abst 2006)
9-Tetrahydrocannabinol (THC) and AM 404 protect against cerebral ischaemia in gerbils through a mechanism involving cannabinoid and opioid receptors (full - 2007)
Pharmacological elevation of anandamide impairs short-term memory by altering the neurophysiology in the hippocampus. (abst 2011)
The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine-induced dopamine elevations in the nucleus accumbens shell in rats (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21557729/abstract/The_anandamide_transport_inh ibitor_AM404_reduces_the_rewarding_effects_of_nicotine_and_nicotine_induced_dopamine_elevations_i n_the_nucleus_accumbens_shell_in_rats_
41
The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine-induced dopamine elevations in the nucleus accumbens shell in rats. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21557729
AM-630 - synthetic, CB2 antagonist Cannabinoid CB2 receptor activation reduces mouse myocardial ischemia-reperfusion injury: involvement of cytokine/chemokines and PMN (full - 2003)
Antinociceptive effect of cannabinoid agonist WIN 55,2122 in rats with a spinal cord injury (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1861843/?tool=pmcentrez Inhibition of Salivary Secretion by Activation of Cannabinoid Receptors (full - 2006)
Regulation of Bone Mass, Osteoclast Function, and Ovariectomy-Induced Bone Loss by the Type 2 Cannabinoid Receptor (full - 2008)
http://endo.endojournals.org/cgi/content/full/149/11/5619?maxtoshow=&hits=80&RESULTFORMAT=&f ulltext=cannabinoid&searchid=1&FIRSTINDEX=240&resourcetype=HWCIT
Cannabinoid CB2 Receptor Potentiates Obesity-Associated Inflammation, Insulin Resistance and Hepatic Steatosis (full - 2009)
A nonsynonymous polymorphism in cannabinoid CB2 receptor gene is associated with eating disorders in humans and food intake is modified in mice by its ligands. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/19768813 Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines. (full 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930808/?tool=pubmed Cannabinoid receptor-2 (CB2) agonist ameliorates colitis in IL-10(-/-) mice by attenuating the activation of T cells and promoting their apoptosis. (abst 2011)
42
AM -678 - see JWH -100
AM-694 synthetic, CB1 & CB2 agonist Beyond THC: The New Generation of Cannabinoid Designer Drugs. (full 2011)
The impact of changes in UK classification of the synthetic cannabinoid receptor agonists in 'Spice'. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21482092
AM-1241 - synthetic, CB 2 agonist Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: Pain inhibition by receptors not present in the CNS (full - 2003)
http://www.pnas.org/content/100/18/10529.full
New Compound That Acts On Peripheral Receptors May Be Promising Treatment For Some Nerve Pain (news - 2003)
CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids (full - 2005) http://www.pnas.org/content/102/8/3093.full Cannabinoid CB2 receptor agonist activity in the hindpaw incision model of postoperative pain. (abst - 2005) http://www.ncbi.nlm.nih.gov/pubmed/16316653 In vitro pharmacological characterization of AM1241: a protean agonist at the cannabinoid CB2 receptor? (full - 2006)
AM1241, a cannabinoid CB2 receptor selective compound, delays disease progression in a mouse model of amyotrophic lateral sclerosis. (abst - 2006)
Peripheral Cannabinoids Attenuate Carcinoma Induced Nociception in Mice (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771220/
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Selective Activation of Cannabinoid CB2 Receptors Suppresses Neuropathic Nociception Induced by Treatment with the Chemotherapeutic Agent Paclitaxel in Rats (full - 2008)
http://jpet.aspetjournals.org/content/327/2/584.full#content-block

(abst - 2008)
Activation of the cannabinoid 2 receptor (CB2) protects against experimental colitis. (full - 2009) http://onlinelibrary.wiley.com/doi/10.1002/ibd.20960/full Spinal and peripheral analgesic effects of the CB cannabinoid receptor agonist AM1241 in two models of bone cancer-induced pain. (full - 2010)
A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20176037 Cannabinoids attenuate cancer pain and proliferation in a mouse model.
(abst - 2010)
Self-medication of a cannabinoid CB(2) agonist in an animal model of neuropathic pain. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21550725/abstract/Self_medication_of_a_cannabin oid_CB_2__agonist_in_an_animal_model_of_neuropathic_pain_
Regulation of hematopoietic stem cell trafficking and mobilization by the endocannabinoid system. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22074629 Cannabinoid receptor 2 and its agonists mediate hematopoiesis and hematopoietic stem and progenitor cell mobilization. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21063029 Antinociceptive effects induced through the stimulation of spinal cannabinoid type 2 receptors in chronically inflamed mice (abst - 2011)
http://www.unboundmedicine.com/medline/ebm/record/21771590/abstract/Antinociceptive_effects_induce d_through_the_stimulation_of_spinal_cannabinoid_type_2_receptors_in_chronically_inflamed_mice_
AM-1346 - synthetic, CB1 agonist Synthetic Cannabinoid May Aid Fertility In Smokers
(news - 2006)
Marijuana-like Chemical Can Restore Sperm Function Lost to Tobacco Abuse (news - 2006) http://www.rxpgnews.com/specialtopics/article_5093.shtml
44
Cannabis-based boost for smokers' suffering sperm
(news - 2006) (news - 2008)
http://www.newscientist.com/article/dn10362-cannabisbased-boost-for-smokers-suffering-sperm.html
Scientist Discovers New Molecule to Treat Chronic Pain

AM-1710 synthetic, CB2 agonist Pharmacological characterization of AM1710, a putative cannabinoid CB(2) agonist from the cannabilactone class: Antinociception without central nervous system side-effects. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21382397/abstract/Pharmacological_characterizati on_of_AM1710_a_putative_cannabinoid_CB_2__agonist_from_the_cannabilactone_class:_Antinociceptio n_without_central_nervous_system_side_effects_
AM -2233 synthetic, CB1 agonist F200A substitution in the third transmembrane helix of human cannabinoid CB1 receptor converts AM2233 from receptor agonist to inverse agonist. (abst 2006)
Evaluation of the in vivo receptor occupancy for the behavioral effects of cannabinoids using a radiolabeled cannabinoid receptor agonist, R-[125/131I]AM2233. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16715483 Another nail in coffin of synthetic cannabis (news 2011)
http://tvnz.co.nz/national-news/another-nail-in-coffin-synthetic-cannabis-4666168?ref=rss
AM- 4054 - synthetic, CB1 agonist Behavioral Profile of the Novel Cannabinoid Agonist AM4054 (thesis - 2006)
http://digitalcommons.uconn.edu/cgi/viewcontent.cgi?article=1016&context=srhonors_theses&seiredir=1#search=%22am-4054%20%2Bcannabinoid%22
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Effects of a Selective Cannabinoid Agonist and Antagonist on Body Temperature in Rats (abst - 2007)
http://www.fasebj.org/cgi/content/meeting_abstract/21/5/A409?maxtoshow=&hits=80&RESULTFORMA T=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=800&resourcetype=HWCIT
AM- 4113 synthetic, CB1 antagonist Effects of a Selective Cannabinoid Agonist and Antagonist on Body Temperature in Rats (abst - 2007)
The neutral cannabinoid CB receptor antagonist AM4113 regulates body weight through changes in energy intake in the rat. (abst 2011)
AM 6545 synthetic, CB1 antagonist Rehashing endocannabinoid antagonists: can we selectively target the periphery to safely treat obesity and type 2 diabetes? (full 2010)
http://www.jci.org/articles/view/44099?search[abstract_text]=&search[article_text]=cannabinoid&search[a uthors_text]=&search[fpage]=&search[title_text]=&search[volume]=
AMOTIVATIONAL SYNDROME Marihuana Use and Psychosocial Adaptation (abst - 1974)

http://archpsyc.amaassn.org/cgi/content/abstract/31/5/713?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuana& searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
Ganja in Jamaica (book 1976) http://www.cifas.us/cannabis/PDFs/OCRGanjainJamaica.pdf Operant acquisition of marihuana in man. (abst - 1976)
http://jpet.aspetjournals.org/content/198/1/42.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=marihuana&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
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Marihuana use. Biologic and behavioral aspects.

(abst 1976)
Cannabis amotivational syndrome and personality trait absorption: A review and reconceptualization (full - 1994) http://www.ukcia.org/research/PersonalityTraitAbsorption.php Debunking the Amotivational Syndrome
http://www.drugscience.org/Petition/C3F.html
(news - 1995)
Lifetime Prevalence of "Amotivational Syndrome" (full 2005)

http://www.addictioninfo.org/articles/262/1/Lifetime-Prevalence-of-Amotivational-Syndrome/Page1.html
Cannabis, motivation, and life satisfaction in an internet sample

(full - 2006)
Debunking "Amotivational Syndrome"
(news - 2006) (news - 2006)
Cannabis Use Not Linked To So-Called "Amotivational Syndrome"

http://norml.org/index.cfm?Group_ID=6824
ANANDAMIDE / AEA endocannabinoid, CB 1 & 2 agonist Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor. (abst 1992)
http://medical-journals.healia.com/doc/1470919/Isolation-and-structure-of-a-brain-constituent-that-bindsto-the-cannabinoid-receptor
Cross-tolerance between delta-9-tetrahydrocannabinol and the cannabimimetic agents, CP 55,940, WIN 55,212-2 and anandamide. (full - 1993)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175863/?tool=pmcentrez&page=1
Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction (full - 1993)
http://www.pnas.org/content/90/16/7656.full.pdf+html
Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes (full - 1994) http://www.pnas.org/content/91/14/6698.full.pdf+html Formation and inactivation of endogenous cannabinoid anandamide in central neurons. (letter 1994) http://www.nature.com/nature/journal/v372/n6507/abs/372686a0.html Anandamide amidohydrolase activity in rat brain microsomes. Identification and partial characterization. (full 1995) http://www.jbc.org/content/270/11/6030.long
47
Anandamide and delta 9-THC dilation of cerebral arterioles is blocked by indomethacin (abst - 1995)
http://ajpheart.physiology.org/cgi/content/abstract/269/6/H1859?maxtoshow=&hits=80&RESULTFORMA T=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=2320&resourcetype=HWCIT
Occurrence and biosynthesis of endogenous cannabinoid precursor, N-arachidonoyl phosphatidylethanolamine, in rat brain. (full 1997)
http://www.jneurosci.org/content/17/4/1226.long
Cannabinoid-Induced Hypotension and Bradycardia in Rats Is Mediated by CB1-Like Cannabinoid Receptors (full - 1997)
http://jpet.aspetjournals.org/content/281/3/1030.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext =cannabinoid&searchid=1&FIRSTINDEX=320&resourcetype=HWCIT
Patent 5631297 - Anandamides useful for the treatment of intraocular hypertension, ophthalmic compositions containing the same and methods of use of the same (full 1997) http://www.patentstorm.us/patents/5631297/fulltext.html Anandamide : The molecule of extreme pleasure
http://www.chm.bris.ac.uk/motm/anandamide/ananh.htm
(report 1997)
Brain Chemicals Mimic Marijuana (news - 1997) http://www.ukcia.org/research/anandami.php Anandamide, an Endogenous Cannabinoid, Has a Very Low Physical Dependence Potential (full - 1998)
The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation (full - 1998) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC20983/ Trick or treat from food endocannabinoids? (abst 1998)
http://www.nature.com/nature/journal/v396/n6712/full/396636a0.html
Doped skin (news - 1998) http://www.newscientist.com/article/mg15921434.700-doped-skin.html Pain modulation by release of the endogenous cannabinoid anandamide
(full - 1999)
Cannabis: Discrimination of "Internal Bliss"?
(abst 1999)
http://medical-journals.healia.com/doc/10515300/Cannabis-discrimination-of-internal-bliss
Brain Releases Marijuana-Like Substance In Response To Pain, Study Finds (news - 1999) http://www.sciencedaily.com/releases/1999/10/991013074947.htm UC Irvine Researchers Demonstrate How Marijuana-Like Chemicals Work In The Brain (news - 1999) http://www.sciencedaily.com/releases/1999/03/990323050735.htm
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Why your brain is primed for a high
(news - 1999)
http://www.newscientist.com/article/mg16121792.000-why-your-brain-is-primed-for-a-high.html
Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors (full - 2000)

(full - 2000)
Suppression of Nerve Growth Factor Trk Receptors and Prolactin Receptors by Endocannabinoids Leads to Inhibition of Human Breast and Prostate Cancer Cell Proliferation (full - 2000) http://endo.endojournals.org/cgi/content/full/141/1/118 Effects of cannabinoid receptor agonists on neuronally-evoked contractions of urinary bladder tissues isolated from rat, mouse, pig, dog, monkey and human (full - 2000)
(abst - 2000)
Low dose anandamide affects food intake, cognitive function, neurotransmitter and corticosterone levels in diet-restricted mice. (abst 2000)
Anandamide and diet: inclusion of dietary arachidonate and docosahexaenoate leads to increased brain levels of the corresponding N-acylethanolamines in piglets. (full 2001) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC33480/?tool=pubmed Cannabinoid CB1-receptor mediated regulation of gastrointestinal motility in mice in a model of intestinal inflammation (full - 2001)
Inhibition of Rat C6 Glioma Cell Proliferation by Endogenous and Synthetic Cannabinoids. Relative Involvement of Cannabinoid and Vanilloid Receptors (full - 2001) http://jpet.aspetjournals.org/content/299/3/951.full Exogenous anandamide protects rat brain against acute neuronal injury in vivo. (full 2001) http://www.jneurosci.org/content/21/22/8765.long Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats (full - 2001) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573067/?tool=pmcentrez Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells (full - 2001)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1222054/pdf/11485574.pdf/?tool=pmcentrez
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Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries (full - 2001) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573021/?tool=pmcentrez Endogenous cannabinoids mediate hypotension after experimental myocardial infarction (full - 2001)
Anandamide activates peripheral nociceptors in normal and arthritic rat knee joints (full - 2001) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1572613/?tool=pmcentrez Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase (full - 2001)
Leptin-regulated endocannabinoids are involved in maintaining food intake (letter 2001) http://www.nature.com/nature/journal/v410/n6830/full/410822a0.html Endogenous cannabinoid anandamide increases heart resistance to arrhythmogenic effects of epinephrine: role of CB(1) and CB(2) receptors. (abst - 2001)
The Central Cannabinoid Receptor Inactivation Suppresses Endocrine Reproductive Functions. (abst 2001)
http://medical-journals.healia.com/doc/11394887/The-central-cannabinoid-receptor-inactivationsuppresses-endocrine-reproductive-functions
Quantification of anandamide content in animal cells and tissues: the normalization makes the difference (full - 2002) http://www.lipidworld.com/content/1/1/4 Sourcing the Code: Searching for the Evolutionary Origins of Cannabinoid Receptors, Vanilloid Receptors, and Anandamide (full 2002)
Estrogen stimulates arachidonoylethanolamide release from human endothelial cells and platelet activation (full 2002) http://bloodjournal.hematologylibrary.org/content/100/12/4040.full Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease (full - 2002)
http://bloodjournal.hematologylibrary.org/cgi/content/full/100/2/627?ijkey=eb71d6d7a06f311440761cfac6 a7d081bcc2771d
A Peripheral Mechanism for CB1 Cannabinoid Receptor-Dependent Modulation of Feeding (full - 2002)
http://www.jneurosci.org/cgi/content/abstract/22/21/9612?ijkey=328b5e83d7be9297b9483d22e0d6319fa0a 862e8&keytype2=tf_ipsecsha
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Experimental parkinsonism alters endocannabinoid degradation: implications for striatal glutamatergic transmission. (full 2002) http://www.jneurosci.org/content/22/16/6900.long Endogenous cannabinoids improve myocardial resistance to arrhythmogenic effects of coronary occlusion and reperfusion: a possible mechanism. (abst - 2002)
Anandamide and noladin ether prevent neurotoxicity of the human amyloid-beta peptide. (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/12384227 Changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine. (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/12393235 Role of Endogenous Cannabinoids in Synaptic Signaling (full - 2003)
Cannabinoid receptor type 1 modulates excitatory and inhibitory neurotransmission in mouse colon (full 2003)
CB1 cannabinoid receptor antagonism promotes remodeling and cannabinoid treatment prevents endothelial dysfunction and hypotension in rats with myocardial infarction (full - 2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573770/?tool=pmcentrez A new endothelial target for cannabinoids. (full -2003)
The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis (full - 2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC166293/ Endocannabinoids protect the rat isolated heart against ischaemia (full - 2003)
Cannabis and the brain. (full - 2003) http://brain.oxfordjournals.org/cgi/content/full/126/6/1252 Chronic Morphine Modulates the Contents of the Endocannabinoid, 2-Arachidonoyl Glycerol, in Rat Brain (full - 2003)
Manipulation of the endocannabinoid system by a general anaesthetic.

(full 2003) (full - 2003)
Cannabinoids inhibit neurodegeneration in models of multiple sclerosis
http://brain.oxfordjournals.org/cgi/content/full/126/10/2191?ijkey=c7c6bfd158b85c98cb1a190d5ca261455 2989ba0
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Therapeutic potential of cannabinoids in CNS disease.

(abst - 2003)
Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: implication of epidermal growth factor receptor down-regulation and ceramide production. (abst - 2003) http://www.ncbi.nlm.nih.gov/pubmed/12746841?dopt=Abstract Inhibition of C6 glioma cell proliferation by anandamide, 1-arachidonoylglycerol, and by a water soluble phosphate ester of anandamide: variability in response and involvement of arachidonic acid. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12948856 Therapeutic potential of cannabinoids in CNS disease.
(abst - 2003)
Cannabinoid influences on palatability: microstructural analysis of sucrose drinking after delta(9)-tetrahydrocannabinol, anandamide, 2-arachidonoyl glycerol and SR141716. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12447606 An endogenous cannabinoid tone attenuates cholera toxin-induced fluid accumulation in mice. (abst - 2003) http://www.ncbi.nlm.nih.gov/pubmed/12949722 Anandamide enhances extracellular levels of adenosine and induces sleep: an in vivo microdialysis study. (abst - 2003)
The endocannabinoid system: a general view and latest additions

(full - 2004)
Endocannabinoids: Getting the message across
(full - 2004)
http://www.pnas.org/content/101/23/8512.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=can nabis&searchid=1&FIRSTINDEX=2880&resourcetype=HWCIT
Endocannabinoids and Their Implications for Epilepsy
(full - 2004)
Anandamide Is Able to Inhibit Trigeminal Neurons Using an in Vivo Model of Trigeminovascular-Mediated Nociception (full - 2004)
http://jpet.aspetjournals.org/content/309/1/56.full
The complexities of the cardiovascular actions of cannabinoids

(full - 2004)
Involvement of cannabinoid receptors in gut motility and visceral perception (full - 2004) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574910/?tool=pmcentrez
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Plasma Levels of the Endocannabinoid Anandamide in WomenA Potential Role in Pregnancy Maintenance and Labor? (full - 2004)
http://jcem.endojournals.org/cgi/content/full/89/11/5482?ijkey=5e8ec5690352ba9f6b990355b2ed69b1d2e5 8a5b
Arachidonyl ethanolamide induces apoptosis of uterine cervix cancer cells via aberrantly expressed vanilloid receptor-1 (full - 2004)
http://science.iowamedicalmarijuana.org/pdfs/cancer/Contassot%202004.pdf
A Cyclooxygenase Metabolite of Anandamide Causes Inhibition of Interleukin-2 Secretion in Murine Splenocytes (full 2004)
Anandamide is an endogenous inhibitor for the migration of tumor cells and T lymphocytes. (abst - 2004) http://www.ncbi.nlm.nih.gov/pubmed/16574988 How our brains fend off madness, we produce a cannabis like substance
http://www.medicalnewstoday.com/releases/12516.php
(news 2004)
Cardiovascular Pharmacology of Cannabinoids
(full - 2005) (full - 2005)
The cardiovascular actions of anandamide: more targets?
Cannabinoids promote hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects (full - 2005) http://www.jci.org/cgi/content/full/115/11/3104 Antidepressant-like Activity and Modulation of Brain Monoaminergic Transmission by Blockade of Anandamide Hydrolysis. (full 2005)
http://www.pnas.org/content/102/51/18620.long
Blood pressure regulation by endocannabinoids and their receptors (full - 2005)

The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2 (full - 2005)
The effects of 9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide (full - 2005)
Anandamide reduces infarct size in rat isolated hearts subjected to ischaemiareperfusion by a novel cannabinoid mechanism (full - 2005)
53
Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity (full - 2005)
Antidepressant-like activity by blockade of anandamide hydrolysis
(full - 2005)
Blood levels of the endocannabinoid anandamide are increased in anorexia nervosa and in binge-eating disorder, but not in bulimia nervosa. (full 2005)
Analgesia through endogenous cannabinoids
(full - 2005)
Cannabinoids augment the release of neuropeptide Y in the rat hypothalamus (abst 2005) http://www.sciencedirect.com/science/article/pii/S0028390805001668 Anandamide Induced Anti-Convulsion in an In Vitro Model of Epilepsy (abst - 2005)
http://www.kau.edu.sa/centers/spc/jkau/Doc/Med/12/Mada.pdf
Influence of Anandamide, the Endogenous Agonist of Cannabinoid Receptors on the Circulatory System (abst - 2005)
http://medical-journals.healia.com/doc/15928605/Influence-of-anandamide-the-endogenous-agonist-ofcannabinoid-receptors-on-the-circulatory-system
Finding of endocannabinoids in human eye tissues: implications for glaucoma. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/15823551 A biosynthetic pathway for anandamide (full - 2006)
Activation of G-proteins in brain by endogenous and exogenous cannabinoids. (full 2006) http://www.ncbi.nlm.nih.gov/pubmed/16584117 Regulation, Function, and Dysregulation of Endocannabinoids in Models of Adipose and -Pancreatic Cells and in Obesity and Hyperglycemia (full - 2006)
Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P (full 2006) http://gut.bmj.com/content/55/7/946.full Endocannabinoids, feeding and suckling from our perspective
(full 2006)
Stage-variations of anandamide hydrolase activity in the mouse uterus during the natural oestrus cycle ( full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440866/?tool=pubmed
54
Increasing cannabinoid levels by pharmacological and genetic manipulation delay disease progression in SOD1 mice (full - 2006) http://www.fasebj.org/cgi/content/full/20/7/1003 Up-regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation. (full 2006)
http://www.fasebj.org/content/early/2006/03/01/fj.05-4943fje.long

Endocannabinoids potently protect the newborn brain against AMPA-kainate receptormediated excitotoxic damage (full - 2006)
Inhibition of Salivary Secretion by Activation of Cannabinoid Receptors
(full - 2006)
Not Too Excited? Thank Your Endocannabinoids
(full - 2006)
Effect of N-arachidonoyl-(2-methyl-4-hydroxyphenyl) amine (VDM11), an anandamide transporter inhibitor, on capsaicin-induced cough in mice (full - 2006)
Effects of general anesthesia on anandamide blood levels in humans.
(full 2006)
http://journals.lww.com/anesthesiology/Fulltext/2006/02000/Effects_of_General_Anesthesia_on_Anandam ide_Blood.12.aspx
Cannabinoids and the Endocannabinoid System
(full - 2006) ( full 2006)
Is there a temperature-dependent uptake of anandamide into cells?

A new strategy to block tumor growth by inhibiting endocannabinoid inactivation. (full 2006) http://www.fasebj.org/content/early/2004/10/02/fj.04-1754fje.long The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cells. (abst 2006)
Local interactions between anandamide, an endocannabinoid, and ibuprofen, a nonsteroidal anti-inflammatory drug, in acute and inflammatory pain (abst - 2006)
55
Methods evaluating cannabinoid and endocannabinoid effects on gastrointestinal functions. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16506408 Role of cannabinoid receptor agonists in mechanisms of suppression of central pain syndrome. (abst - 2006)
Anandamide inhibits adhesion and migration of breast cancer cells.

(abst - 2006)
Acyl-based anandamide uptake inhibitors cause rapid toxicity to C6 glioma cells at pharmacologically relevant concentrations. (abst 2006)
Human adipose tissue binds and metabolizes the endocannabinoids anandamide and 2arachidonoylglycerol. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16949718 Anxiolytic-like properties of the anandamide transport inhibitor AM404.
(abst 2006)
Endocannabinoids and beta-amyloid-induced neurotoxicity in vivo: effect of pharmacological elevation of endocannabinoid levels. (abst 2006)
UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders. (abst 2006)
Metabolism of Anandamide an Endogenous Cannabinoid
(chart 2006)
http://pid.nci.nih.gov/search/pathway_landing.shtml?source=BioCarta%20Imported&what=graphic&jpg=o n&ppage=1&pathway_id=cb1rpathway
Anandamide Regulates Keratinocyte Differentiation by Inducing DNA Methylation in a CB1 Receptor-dependent Manner (full 2007) http://www.jbc.org/content/283/10/6005.full Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228252/?tool=pmcentrez Endocannabinoid metabolism and uptake: novel targets for neuropathic and inflammatory pain (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190014/?tool=pubmed Anandamide and Delta9-tetrahydrocannabinol directly inhibit cells of the immune system via CB2 receptors. (full - 2007)
56
Anandamide Regulates Keratinocyte Differentiation by Inducing DNA Methylation in a CB1 Receptor-dependent Manner (full 2007)
http://www.jbc.org/content/283/10/6005.full?sid=931583b1-e797-43e0-8296-7fd75bb49403#sec-4
Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB1 and TRPV1 receptors (full - 2007)
Endocannabinoid hedonic hotspot for sensory pleasure: anandamide in nucleus accumbens shell enhances 'liking' of a sweet reward. (full 2007)
Identification of Endocannabinoids and Related Compounds in Human Fat Cells (full - 2007) http://www.nature.com/oby/journal/v15/n4/full/oby2007100a.html Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190006/?tool=pmcentrez Endocannabinoids and the haematological system (full - 2007)
Characterization of the vasorelaxant mechanisms of the endocannabinoid anandamide in rat aorta (full 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190007/?tool=pubmed The CB1 Cannabinoid Receptor Mediates Excitotoxicity-induced Neural Progenitor Proliferation and Neurogenesis (full - 2007) http://www.jbc.org/content/282/33/23892.full Chronologically overlapping occurrences of nicotine-induced anxiety- and depressionrelated behavioral symptoms: effects of anxiolytic and cannabinoid drugs (full - 2007)
Involvement of the Endocannabinoid System in Retinal Damage after High Intraocular PressureInduced Ischemia in Rats (full - 2007)
http://www.iovs.org/cgi/content/full/48/7/2997?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=can nabis&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT
Anandamide inhibits cholangiocyte hyperplastic proliferation via activation of thioredoxin 1/redox factor 1 and AP-1 activation (full 2007)
http://ajpgi.physiology.org/content/294/2/G506.full
Opposing Actions of Endocannabinoids on Cholangiocarcinoma Growth (full - 2007) http://www.jbc.org/content/282/17/13098.full Endocannabinoids, cannabinoid receptors and inflammatory stress: an interview with Dr. Pl Pacher (interview - 2007)
57
Antiangiogenic activity of the endocannabinoid anandamide: correlation to its tumorsuppressor efficacy. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17192847 The endocannabinoids anandamide and 2-arachidonoylglycerol inhibit cholinergic contractility in the human colon. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17706636 Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients (abst - 2007)
http://www.unboundmedicine.com/medline/ebm/record/17566707/abstract/Anandamide_levels_in_cerebro spinal_fluid_of_first_episode_schizophrenic_patients:_Impact_of_cannabis_use
Antidepressant-like activity of the fatty acid amide hydrolase inhibitor URB597 in a rat model of chronic mild stress. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17511970 Marijuana-Like Brain Chemicals Work As Antidepressant
(news - 2007)
Role seen for cannabis in helping to alleviate allergic skin disease (news - 2007)
CB1 Cannabinoid Receptor Inhibition: Promising Approach for Heart Failure? (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669829/?tool=pmcentrez N-arachidonylethanolamide-Induced Increase in Aqueous Humor Outflow Facility (full - 2008) http://www.iovs.org/cgi/content/full/49/10/4528 Pharmacological Inhibition of CB1 Cannabinoid Receptor Protects Against DoxorubicinInduced Cardiotoxicity (full - 2008) http://content.onlinejacc.org/cgi/content/full/50/6/528 Modulation of the Endocannabinoid System in Cardiovascular Disease
(full - 2008)
Cannabinoid receptors and the regulation of bone mass
(full - 2008)
Ulcerative colitis in AKR mice is attenuated by intraperitoneally administered anandamide. (full 2008)
http://www.jpp.krakow.pl/journal/archive/12_08/pdf/673_12_08_article.pdf
58
Endocannabinoids and the Control of Energy Homeostasis
(full 2008)
The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway (full - 2008)
The anandamide analog, Met-F-AEA, controls human breast cancer cell migration via the RHOA/RHO kinase signaling pathway. (full 2008)
http://erc.endocrinology-journals.org/cgi/content/full/15/4/965
Role of cannabinoids and endocannabinoids in cerebral ischemia

(full - 2008)
Endocannabinoid Dysregulation in the Pancreas and Adipose Tissue of Mice Fed With a High-fat Diet (full - 2008) http://www.nature.com/oby/journal/v16/n3/full/oby2007106a.html Endocannabinoids and nutrition. (full 2008)
Role of endocannabinoids and their analogues in obesity and eating disorders. (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/19011363 Mechanisms for Recycling and Biosynthesis of Endogenous Cannabinoids Anandamide and 2-Arachidonylglycerol (full - 2008)
Inhibition of anandamide hydrolysis by URB597 reverses abuse-related behavioral and neurochemical effects of nicotine in rats. (abst 2008)
The endocannabinoid system: emotion, learning and addiction.

(abst - 2008) (abst - 2008)
Anandamide and neutrophil function in patients with fibromyalgia.

Understanding the effects of endogenous cannabinoids
(news - 2008) (news - 2008)

Endocannabinoids and the Heart
(full - 2009) (full - 2009)
Cannabinoids, Endocannabinoids, and Related Analogs in Inflammation

59
Localisation and Function of the Endocannabinoid System in the Human Ovary (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640464/?tool=pmcentrez Changes in the Endocannabinoid System May Give Insight into new and Effective Treatments for Cancer (full - 2009)
Endogenous cannabinoids induce fever through the activation of CB1 receptors. (full 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765314/?tool=pubmed Biomarkers of Endocannabinoid System Activation in Severe Obesity (full - 2009)
Endocannabinoids and Their Receptors as Targets for Obesity Therapy (full - 2009)
The endocannabinoid system in bull sperm and bovine oviductal epithelium: role of anandamide in sperm-oviduct interaction. (full - 2009)
http://www.reproduction-online.org/cgi/content/full/137/3/403
Modulation of motor and sensory pathways of the peristaltic reflex by cannabinoids. (full 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739820/?tool=pubmed The Endocannabinoid Anandamide: From Immunomodulation to Neuroprotection. Implications for Multiple Sclerosis (abst - 2009)
Characterization of the Endocannabinoid System in Human Neuronal Cells and Proteomic Analysis of Anandamide-induced Apoptosis (full 2009)
Association of CNR1 and FAAH endocannabinoid gene polymorphisms with anorexia nervosa and bulimia nervosa: evidence for synergistic effects. (abst 2009)
Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines. (abst 2009) http://www.ncbi.nlm.nih.gov/pubmed/19394652 Circulating endocannabinoid concentrations during orthostatic stress
(abst 2009)
Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19502530 Endocannabinoids prevent lysosomal membrane destabilisation evoked by treatment with -amyloid in cultured rat cortical neurons (abst 2009)
60
A metabolically stable analogue of anandamide, Met-F-AEA, inhibits human thyroid carcinoma cell lines by activation of apoptosis (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19189054/abstract/A_metabolically_stable_analog ue_of_anandamide_Met_F_AEA_inhibits_human_thyroid_carcinoma_cell_lines_by_activation_of_apopto sis_
Is GPR55 an anandamide receptor?

(abst - 2009)
Opposing actions of endocannabinoids on cholangiocarcinoma growth is via the differential activation of Notch signaling. (full 2010)
Cannabinoid Receptors as Target for Treatment of Osteoporosis: A Tale of Two Therapies (full 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001217/?tool=pubmed Cannabinoid-mediated inhibition of recurrent excitatory circuitry in the dentate gyrus in a mouse model of temporal lobe epilepsy. (full 2010)

(full - 2010)
Endocannabinoids and Schizophrenia

(full 2010)
Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients (full - 2010)
The endocannabinoid system as a target for the treatment of neurodegenerative disease (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931550/?tool=pubmed Alterations in the hippocampal endocannabinoid system in diet-induced obese mice. (full 2010) http://www.jneurosci.org/content/30/18/6273.long Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition. (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227620/?tool=pubmed The endogenous cannabinoid, anandamide, induces COX-2-dependent cell death in apoptosis-resistant colon cancer cells. (abst, link to PDF - 2010)
http://www.spandidos-publications.com/ijo/37/1/187
Effects of anandamide on polyamine levels and cell growth in human colon cancer cells (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20682986
61
Circulating and hepatic endocannabinoids and endocannabinoid-related molecules in patients with cirrhosis. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/19840245 Non-CB1, non-CB2 receptors for endocannabinoids, plant cannabinoids, and synthetic cannabimimetics: focus on G-protein-coupled receptors and transient receptor potential channels. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/19847654/abstract/Non_CB1_non_CB2_receptors _for_endocannabinoids_plant_cannabinoids_and_synthetic_cannabimimetics:_focus_on_G_protein_couple d_receptors_and_transient_receptor_potential_channels_
The Multiplicity of Action of Cannabinoids: Implications for Treating Neurodegeneration. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20875047 Pharmacological exploitation of the endocannabinoid system: new perspectives for the treatment of depression and anxiety disorders? (abst 2010)
Anandamide extends platelets survival through CB(1)-dependent Akt signaling. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/19936621 Interaction between anandamide and sphingosine-1-phosphate in mediating vasorelaxation in rat coronary artery (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20718749/abstract/Interaction_between_anandami de_and_sphingosine_1_phosphate_in_mediating_vasorelaxation_in_rat_coronary_artery_
Anandamide and AM251, via water, modulate food intake at central and peripheral level in fish. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/19800340 Compound boosts marijuana-like chemical in the body to relieve pain at injury site (news - 2010) http://www.eurekalert.org/pub_releases/2010-09/uoc--cbm092010.php Chocolate: The Good, the Bad and the Angry (news - 2010) (news - 2010)
http://www.psychologytoday.com/blog/your-brain-food/201011/chocolate-the-good-the-bad-and-the-angry
Painkilling System in Brain: Too Much of a Good Thing?

Anandamide inhibits Theiler's virus induced VCAM-1 in brain endothelial cells and reduces leukocyte transmigration in a model of blood brain barrier by activation of CB1 receptors. (full 2011)
http://www.jneuroinflammation.com/content/pdf/1742-2094-8-102.pdf
62
Endocannabinoid system in cardiovascular disorders - new pharmacotherapeutic opportunities (full 2011)

http://www.jpbsonline.org/article.asp?issn=09757406;year=2011;volume=3;issue=3;spage=350;epage=360;aulast=Cunha

(full 2011)
Increasing Antiproliferative Properties of Endocannabinoids in N1E-115 Neuroblastoma Cells through Inhibition of Their Metabolism. (full 2011)
Anandamide-loaded nanoparticles: preparation and characterization.

(abst 2011)
Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver (abst 2011)
http://www.pnas.org/content/108/15/6323.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fulltext= cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype=HWCIT
Cannabinoid applications in glaucoma.
(abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21414525/abstract/Cannabinoid_applications_in_g laucoma_
An amyloid (42)-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer's disease (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21546126/abstract/An_amyloid_%CE%B2_42__d ependent_deficit_in_anandamide_mobilization_is_associated_with_cognitive_dysfunction_in_Alzheimer% 27s_disease_
Arachidonoyl ethanolamide (AEA)-induced apoptosis is mediated by J-series prostaglandins and is enhanced by fatty acid amide hydrolase (FAAH) blockade. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21432910/abstract/Arachidonoyl_ethanolamide__ AEA__induced_apoptosis_is_mediated_by_J_series_prostaglandins_and_is_enhanced_by_fatty_acid_ami de_hydrolase__FAAH__blockade_
Intracellular Cannabinoid Type 1 (CB1) Receptors Are Activated by Anandamide (abst 2011)
http://www.jbc.org/content/286/33/29166.abstract?sid=2c3b88ec-b6e6-4245-a171-2e24c17b5e8b
Inhibition of cannabinoid metabolic enzymes reduces NSAID-induced gastric pathology (abst 2011)
http://www.fasebj.org/cgi/content/meeting_abstract/25/1_MeetingAbstracts/807.1?maxtoshow=&hits=80& RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype =HWCIT
Abnormal anandamide metabolism in celiac disease.

(abst 2011)
63
The fatty acid amide hydrolase inhibitor URB 597: interactions with anandamide in rhesus monkeys. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21449917/abstract/The_fatty_acid_amide_hydrolas e_inhibitor_URB_597:_interactions_with_anandamide_in_rhesus_monkeys_
Triphasic blood pressure responses to cannabinoids: do we understand the mechanism? (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22022923 Endocannabinoid CB1 receptors modulate visual output from the thalamus. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21773721 Omega-3 N-acylethanolamines are endogenously synthesised from omega-3 fatty acids in different human prostate and breast cancer cell lines. (abst 2011)
The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine-induced dopamine elevations in the nucleus accumbens shell in rats. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21557729 Marijuana Compound Treats Multiple Health Issues
http://www.foxnews.com/health/2010/03/10/cannabis-deficient/
(news 2011)
Arachidonoyl ethanolamide (AEA)-induced apoptosis is mediated by J-series prostaglandins and is enhanced by fatty acid amide hydrolase (FAAH) blockade. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/21432910 Contrasting protective effects of cannabinoids against oxidative stress and amyloid- evoked neurotoxicity in vitro. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/22233683
64
ANECDOTAL / PERSONAL STORIES ANECDOTAL ARTICLES ADHD by Ryan P (anecdotal - no date)

http://cannabislink.ca/medical/#medanecdotal
(anecdotal - no date) (anecdotal no date) (anecdotal - no date) (anecdotal - no date)
http://www.rxmarijuana.com/shared_comments/ADHD4.htm
Lyme Disease by Cynkay Morningstar Menires Syndrome by Charlie Ritchie Chemotherapy for Testicular Cancer Smoking dope restored my sight Recipe For Trouble
http://rxmarijuana.com/shared_comments/Lyme_Disease.htm
http://www.rxmarijuana.com/shared_comments/ritchie.htm
http://www.rxmarihuana.com/shared_comments/testicularchemo.htm
(news/anecdotal - 1998)
(news/anecdotal - 2002) (news/anecdotal - 2003) (news/ anecdotal- 2004) (anecdotal - 2005)
'How cannabis helped me'
Skin Complaint Man Grew Cannabis
http://www.mapinc.org/drugnews/v04.n1222.a09.html
Testimony of Mr. Rene Carlos Guevara to FDA
http://www.fda.gov/ohrms/dockets/dockets/05n0479/05N-0479-EC4.htm
Testimony of Terry Jacobs to FDA - why he prefers for medical marijuana to Marinol (news/anecdotal - 2005)
http://www.examiner.com/examiner/x-19678-Cannabis-Revolution-Examiner~y2009m11d5-Testimony-ofTerry-Jacobs-to-FDA--why-he-prefers-for-medical-marijuana-to-Marinol
Marijuna Cured My Color-Blindness
(anecdotal 2005) (anecdotal - 2007 - 2010)
http://mmj.tribe.net/thread/ae2e9a56-f117-4e96-b24d-ae799e956b00
Cannabis Sativa (Marijuana) for Fibromyalgia

http://www.fibromyalgia-reviews.com/Drg_Marijuana.cfm
Shared Comments and Observations Why I Give My 9-year-old Pot
(anecdotal - 2009)
http://www.rxmarihuana.com/comments_and_observations.htm
(news/ anecdotal - 2009)
65
Why I Give My 9-Year-Old Pot, Part II
Julie Falco brings hope to Multiple Sclerosis patients. Cannabinoids manage pain and promote repair! (news - 2010)
http://www.examiner.com/x-19678-Cannabis-Revolution-Examiner~y2010m2d10-Julie-Falco-brings-hopeto-Multiple-Sclerosis-patients-Cannabinoids-manage-pain-and-promote-repair
The Cannabis Closet: Severe Eczema
(anecdotal - 2010) (anecdotal - 2010)
http://andrewsullivan.theatlantic.com/the_daily_dish/2010/05/the-cannabis-closet-severe-eczema.html
Cannabis and PTSD by Michael McKenna
http://marijuana-uses.com/cannabis-and-ptsd-by-michael-mckenna/
Steamboat mom sees results from giving autistic son medical marijuana (anecdotal/news - 2010)
http://www.steamboatpilot.com/news/2010/oct/31/steamboat-mom-sees-results-giving-autistic-son-med/
Up in smoke: 'Cannabis gave me my life back' (anecdotal 2010)

http://www.independent.co.uk/life-style/health-and-families/features/up-in-smoke-cannabis-gave-me-mylife-back-2041640.html
Why I Give My 9-Year-Old Pot, Part 3 Why I Give My Autistic Son Pot, Part 4
(news - 2010) (news 2011)
Father: Medical marijuana eased pain of my cancer-battling son (anecdotal 2011)

http://www.komonews.com/news/local/120941429.html
ANOREXIA NERVOSA - also see APPETITE STIMULANT Leptin-regulated endocannabinoids are involved in maintaining food intake (letter 2001) http://www.nature.com/nature/journal/v410/n6830/full/410822a0.html Association study of cannabinoid receptor gene (CNR1) alleles and anorexia nervosa: differences between restricting and binging/purging subtypes. (abst 2004)
Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects (full 2008) http://gut.bmj.com/content/57/8/1140.full
66
Lack of association of genetic variants in genes of the endocannabinoid system with anorexia nervosa (full - 2008) http://www.capmh.com/content/2/1/33 Role of endocannabinoids and their analogues in obesity and eating disorders. (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/19011363 Elevated cannabinoid 1 receptor mRNA is linked to eating disorder related behavior and attitudes in females with eating disorders. (abst 2009)
Activity-based anorexia in C57/BL6 mice: effects of the phytocannabinoid, Delta9tetrahydrocannabinol (THC) and the anandamide analogue, OMDM-2. (abst 2010)
Molecular mechanisms underlying anorexia nervosa: focus on human gene association studies and systems controlling food intake. (abst 2010)
A nonsynonymous polymorphism in cannabinoid CB2 receptor gene is associated with eating disorders in humans and food intake is modified in mice by its ligands. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/19768813 The genetics of eating disorders. (abst 2011)
Brain Type 1 Cannabinoid Receptor Availability in Patients with Anorexia and Bulimia Nervosa. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21718968 Functional polymorphism in the GPR55 gene is associated with anorexia nervosa. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/20506567 The cannabinoid receptor agonist THC attenuates weight loss in a rodent model of activity-based anorexia. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21412227 Fish oil promotes survival and protects against cognitive decline in severely undernourished mice by normalizing satiety signals. (abst 2011)
Do Deficits in Brain Cannabinoids Contribute to Eating Disorders? (news 2011) http://www.sciencedaily.com/releases/2011/10/111031115226.htm
67
ANTI-BACTERIAL PROPERTIES HEMP AS A MEDICAMENT : Methods and results of the bacteriological experiments (full - 1955)
https://www.greenpassion.org/index.php?/topic/23448-methods-and-results-of-the-bacteriologicalexperiments/
Antibacterial preparation from hemp (Cannabis sativa)
(abst - 1958)
http://chemport.cas.org/cgibin/sdcgi?APP=ftslink&action=reflink&origin=ACS&version=1.0&coi=1%3ACAS%3A528%3ADyaG1c XpvVGiug%253D%253D&md5=36fcabac61432cf5e852c26c9bba3cd1
Hemp (Cannabis sativa)-an antibiotic drug. II. Methods and results of bacteriological investigations and preliminary clinical experiences (abst - 1958)
http://chemport.cas.org/cgibin/sdcgi?APP=ftslink&action=reflink&origin=ACS&version=1.0&coi=1%3ACAS%3A528%3ADyaG1c Xotl2guw%253D%253D&md5=a36c74726c1c02d8a52d1f297d624fc6
Effect of Biogenic Amines and Cannabinoids on Bacterial Chemotaxis

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC246374/?page=1
(full - 1973) (abst - 1976)
Antibacterial activity of delta9-tetrahydrocannabinol and cannabidiol.
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=1085130&dopt=abstract plus
Biological activity of cannabichromene, its homologs and isomers.

(abst - 1981)
Antiinflammatory and antimicrobial compounds and compositions United States Patent 4837228 (full - 1989) http://www.freepatentsonline.com/4837228.html Antibacterial cannabinoids from Cannabis sativa: a structure-activity study. (full - 2008)
http://www.cannabisasmedicine.com/story/antibacterial-cannabinoids-cannabis-sativastructure%E2%88%92activity-study
Cannabinoids kill hospital superbug MRSA
(news 2008) (news - 2008)
http://www.worldhealth.net/news/cannabinoids_kill_hospital_superbug_mrsa/
Pot is good for you? Marijuana fights the superbugs
http://www.scientificamerican.com/blog/60-second-science/post.cfm?id=whoa-the-stuff-in-pot-kills-germs2008-08-27&sc=rss
Killing bacteria with cannabis
(news - 2008) (news - 2008)
http://arstechnica.com/journals/science.ars/2008/08/26/killing-bacteria-with-cannabis
New biologically active compounds from cannabis
http://arstechnica.com/science/news/2009/04/new-biologically-active-compounds-from-cannabis.ars
68
A New MRSA Defense
(news - 2008) (news - 2008) (abst - 2009)
http://www.technologyreview.com/biomedicine/21366/?a=f
Chemicals in Marijuana May Fight MRSA
http://www.webmd.com/news/20080904/marijuana-chemicals-may-fight-mrsa
Biologically Active Cannabinoids from High-Potency Cannabis sativa.
http://www.unboundmedicine.com/medline/ebm/record/19344127/abstract/Biologically_Active_Cannabino ids_from_High_Potency_Cannabis_sativa_
Characterization and antimicrobial activity of essential oils of industrial hemp varieties (Cannabis sativa L.). (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19969046 Natural plant cannabinoids reduce multi-drug resistant infections
(news - 2009) (news - 2009)
Cannabis Compounds Reduce Multi-Drug Resistant Infections

Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21749363
ANTI-FUNGAL PROPERTIES Biologically Active Cannabinoids from High-Potency Cannabis sativa. (abst - 2009)
ANTI-INFLAMMATORY PROPERTIES Biological activity of cannabichromene, its homologs and isomers.

(abst - 1981)
Analgesic and antiinflammatory activity of constituents of Cannabis sativa L. (full - 1988)

http://www.ukcia.org/research/AnalgesicAndAntiInflammatoryActivityofConstituents.html
Antiinflammatory and antimicrobial compounds and compositions United States Patent 4837228 (full - 1989) http://www.freepatentsonline.com/4837228.html
69
1,1-Dimethylheptyl--8-tetrahydrocannabinol-11-oic Acid: A Novel, Orally Effective Cannabinoid with Analgesic and Anti-inflammatory Properties (full - 1999)
http://jpet.aspetjournals.org/content/291/1/31.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext= marihuana&searchid=1&FIRSTINDEX=1840&resourcetype=HWCIT
Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat (full - 2002)
Cannabidiol-transdermal delivery and anti-inflammatory effect in a murine model. (abst - 2003) http://www.ncbi.nlm.nih.gov/pubmed/14644587 New perspectives in the studies on endocannabinoid and cannabis: 2arachidonoylglycerol as a possible novel mediator of inflammation (full - 2004)
http://www.jstage.jst.go.jp/article/jphs/96/4/367/_pdf
Cannabinoids and neuroinflammation
(full - 2004)
Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation. (full - 2004) http://ajpgi.physiology.org/cgi/content/full/287/1/G7 A novel synthetic, nonpsychoactive cannabinoid acid (HU-320) with antiinflammatory properties in murine collagen-induced arthritis. (full - 2004)
http://onlinelibrary.wiley.com/doi/10.1002/art.20050/full
The cannabinoid receptor agonist WIN 55212-2 inhibits neurogenic inflammations in airway tissues. (full 2005) http://www.jstage.jst.go.jp/article/jphs/98/1/77/_pdf Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation (full - 2005) http://www.jneuroinflammation.com/content/2/1/29 Ajulemic acid (IP-751): Synthesis, proof of principle, toxicity studies, and clinical trials (full - 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751505/?tool=pubmed Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson's disease. (abst - 2005)
Endogenous cannabinoid receptor agonists inhibit neurogenic inflammations in guinea pig airways. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/16103691 Role of the Cannabinoid System in Pain Control and Therapeutic Implications for the Management of Acute and Chronic Pain Episodes (full - 2006)
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Involvement of the Cannabinoid CB2 Receptor and Its Endogenous Ligand 2Arachidonoylglycerol in Oxazolone-Induced Contact Dermatitis in Mice (full 2006)
The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cells. (abst 2006)
Cannabinoid-2 receptor agonist HU-308 protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and apoptosis (full - 2007) http://www.jleukbio.org/cgi/content/full/82/6/1382 Cannabidiol in vivo blunts -amyloid induced neuroinflammation by suppressing IL-1 and iNOS expression (Alzheimer's) (full - 2007)
Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro (full - 2007)
Anti-inflammatory property of the cannabinoid receptor-2-selective agonist JWH-133 in a rodent model of autoimmune uveoretinitis (full - 2007)
http://www.jleukbio.org/cgi/reprint/82/3/532?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=canna binoid&searchid=1&FIRSTINDEX=240&resourcetype=HWCIT
Endocannabinoid metabolism and uptake: novel targets for neuropathic and inflammatory pain (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190014/?tool=pubmed The endocannabinoid system in targeting inflammatory neurodegenerative diseases (full - 2007)
Cannabinoid CB2 receptors: a therapeutic target for the treatment of inflammatory and neuropathic pain (full - 2007)
71

(abst - 2007)
Cannabinoids for the treatment of inflammation.
(abst - 2007)
A cannabinoid agonist differentially attenuates deep tissue hyperalgesia in animal models of cancer and inflammatory muscle pain. (abst 2007)
Constituents Of Hashish And Marijuana May Help To Fight Inflammation And Allergies (news - 2007) http://www.sciencedaily.com/releases/2007/06/070607171120.htm Pot Chemical May Curb Inflammation (news 2007)
http://www.webmd.com/allergies/news/20070607/pot-chemical-may-curb-inflammation
Endocannabinoids appear to play important role in regulating inflammation (news - 2007) http://www.news-medical.net/news/2007/06/08/26114.aspx Marijuana Skin Cream? (news - 2007) (full - 2008)
http://www.jointogether.org/news/research/summaries/2007/marijuana-skin-cream.html
Anti-inflammatory cannabinoids in diet
Cannabinoid receptors in acute and chronic complications of atherosclerosis (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219535/?tool=pmcentrez Cannabinoid receptor stimulation is anti-inflammatory and improves memory in old rats. (full -2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586121/?tool=pubmed Inflammation and aging: can endocannabinoids help? (full - 2008) (full - 2008)

Cannabinoid Modulation of Cutaneous A{delta} Nociceptors During Inflammation (full - 2008) http://jn.physiology.org/cgi/reprint/100/5/2794 Cannabinoid modulation of cutaneous Adelta nociceptors during inflammation. (full 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585399/?tool=pubmed Cannabidiol in medicine: a review of its therapeutic potential in CNS disorders. (abst - 2008)
http://www.unboundmedicine.com/medline/ebm/record/18844286/abstract/Cannabidiol_in_medicine:_a_re view_of_its_therapeutic_potential_in_CNS_disorders_
72
Scientists are High on Idea that Cannabis Reduces Memory Impairment

(news - 2008)
Why Cannabis Stems Inflammation
(news - 2008)
Cannabinoids 9-Tetrahydrocannabinol and Cannabidiol Differentially Inhibit the Lipopolysaccharide-activated NF-B and Interferon-/STAT Proinflammatory Pathways in BV-2 Microglial Cells (full 2009)
http://www.jbc.org/content/285/3/1616.full?sid=43211ca4-a4aa-4182-a554-d15e2835e288
Cannabinoids as Therapeutic Agents for Ablating Neuroinflammatory Disease (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750822/?tool=pmcentrez Cannabidiol Attenuates Cisplatin-Induced Nephrotoxicity by Decreasing Oxidative/Nitrosative Stress, Inflammation, and Cell Death (full 2009)
(full - 2009)
The nonpsychotropic cannabinoid cannabidiol modulates and directly activates alpha-1 and alpha-1-Beta glycine receptor function (full 2009)
http://content.karger.com/produktedb/produkte.asp?DOI=000201556&typ=pdf
Cannabinoids, Endocannabinoids, and Related Analogs in Inflammation (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664885/?tool=pmcentrez Cannabidiol decreases bone resorption by inhibiting RANK/RANKL expression and proinflammatory cytokines during experimental periodontitis in rats. (abst - 2009)
Cannabinoids attenuate the effects of aging upon neuroinflammation and neurogenesis. (abst 2009) http://www.ncbi.nlm.nih.gov/pubmed/19385063
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How Hemp Seed Oil Can Help Your Arthritis
(news 2009)
http://www.thefreelibrary.com/How+Hemp+Seed+Oil+Can+Help+Your+Arthritis-a01074002477
Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression. (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005548/?tool=pubmed Cannabinoids and Viral Infections (full - 2010)
US Patent Application 20100222437 - COMPOSITION CONTAINING NONPSYCHOTROPIC CANNABINOIDS FOR THE TREATMENT OF INFLAMMATORY DISEASES (full 2010)
http://www.patentstorm.us/applications/20100222437/fulltext.html
The endocannabinoid system as a target for the treatment of neurodegenerative disease (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931550/?tool=pubmed The effects of Delta-tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis. (full - 2010)
Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion. (abst - 2010)
Regulatory Role of Cannabinoid Receptor 1 in Stress-Induced Excitotoxicity and Neuroinflammation (abst - 2010)
WIN55212-2 ameliorates atherosclerosis associated with suppression of proinflammatory responses in ApoE-knockout mice. (abst 2010)
Beneficial effects of cannabinoids (CB) in a murine model of allergen-induced airway inflammation: Role of CB(1)/CB(2) receptors. (abst - 2010)
Levels of endocannabinoids and palmitoylethanolamide and their pharmacological manipulation in chronic granulomatous inflammation in rats. (abst 2010)
Cannabidiol reduces lipopolysaccharide-induced vascular changes and inflammation in the mouse brain: an intravital microscopy study (full 2011)
74
Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa (full 2011) http://www.jstage.jst.go.jp/article/bpb/34/5/774/_pdf Gut feelings about the endocannabinoid system (full 2011)
Local activation of cannabinoid CB1 receptors in the urinary bladder reduces the inflammation-induced sensitization of bladder afferents. (full 2011)
http://www.molecularpain.com/content/pdf/1744-8069-7-31.pdf
The Antinociceptive Effects of JWH-015 in Chronic Inflammatory Pain Are Produced by Nitric Oxide-cGMP-PKG-KATP Pathway Activation Mediated by Opioids. (full 2011)
Cannabinoids and Innate Immunity: Taking a Toll on Neuroinflammation (abst- with link to full 2011) http://www.tswj.com/2011/230786/abs/ Increasing endogenous 2-arachidonoylglycerol levels counteracts colitis and related systemic inflammation. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21551239/abstract/Increasing_endogenous_2_arac` hidonoylglycerol_levels_counteracts_colitis_and_related_systemic_inflammation_
Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21238581 GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21467997/abstract/GPR55_regulates_cannabinoid_ 2_receptor_mediated_responses_in_human_neutrophils_
Immunomodulatory properties of kappa opioids and synthetic cannabinoids in HIV-1 neuropathogenesis. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21850403 Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and cell death (abst 2011)
http://www.fasebj.org/cgi/content/meeting_abstract/25/1_MeetingAbstracts/639.12?maxtoshow=&hits=80 &RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=160&sortspec=date&resourcet ype=HWCIT
Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and (9) -tetrahydrocannabinol in BV-2 microglial cells (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21542829/abstract/Differential_transcriptional_pro files_mediated_by_exposure_to_the_cannabinoids_cannabidiol_and_%CE%94_9___tetrahydrocannabinol _in_BV_2_microglial_cells_
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Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21362471/abstract/Cannabidiol_protects_against_h epatic_ischemia/reperfusion_injury_by_attenuating_inflammatory_signaling_and_response_oxidative/nitra tive_stress_and_cell_death_
Deletion of cannabinoid receptors 1 and 2 exacerbates APC function to increase inflammation and cellular immunity during influenza infection. (abst 2011)
A synthetic cannabinoid, CP55940, inhibits lipopolysaccharide-induced cytokine mRNA expression in a cannabinoid receptor-independent mechanism in rat cerebellar granule cells. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21492165/abstract/A_synthetic_cannabinoid_CP55 940_inhibits_lipopolysaccharide_induced_cytokine_mRNA_expression_in_a_cannabinoid_receptor_indep endent_mechanism_in_rat_cerebellar_granule_cells_
Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21175579/abstract/Effects_of_cannabinoids_and_c annabinoid_enriched_Cannabis_extracts_on_TRP_channels_and_endocannabinoid_metabolic_enzymes_
(news 2011)
ANTIMICROBIAL PROPERTIES Susceptibility of Naegleria fowleri to delta 9-tetrahydrocannabinol. (full - 1979)

http://aac.asm.org/cgi/reprint/16/5/674?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuana &searchid=1&FIRSTINDEX=1040&resourcetype=HWCIT
The trypanocidal effect of Cannabis sativa constituents in experimental animal trypanosomiasis. (African Sleeping Sickness) (abst 1994)
The effect of fibre hemp (Cannabis sativa L.) on selected soil-borne pathogens (full 1994) http://druglibrary.org/olsen/hemp/IHA/iha01103.html Endocannabinoids Inhibit the Growth of Free-Living Amoebae
(full 2010)
76
ANTIOXIDANT PROPERTIES Biological screening of 100 plant extracts for cosmetic use (II): anti-oxidative activity and free radical scavenging activity. (abst - 1997)
http://www.unboundmedicine.com/medline/ebm/record/18505484/abstract/Biological_screening_of_100_p lant_extracts_for_cosmetic_use__II_:_anti_oxidative_activity_and_free_radical_scavenging_activity_
Cannabidiol and ()9-tetrahydrocannabinol are neuroprotective antioxidants (full - 1998) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=20965&tool=pmcentrez Cannabinoid Antioxidant Protects Brain Cells -- Without the High
http://hempworld.com/HempPharm/articles/medicalm05.html
(news 1998)
Cannabinoids protect cells from oxidative cell death: a receptor-independent mechanism. (full - 2000) http://jpet.aspetjournals.org/content/293/3/807.full Neuroprotective Antioxidants from Marijuana (abst 2000)
http://onlinelibrary.wiley.com/doi/10.1111/j.17496632.2000.tb06193.x/abstract;jsessionid=2FC02E954345A713B5843BEE89616F4F.d02t01
US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants (full - 2003)

http://www.patentstorm.us/patents/6630507.html
Synergistic Interactions between Cannabinoids and Environmental Stress in the Activation of the Central Amygdala (full - 2005) \http://www.nature.com/npp/journal/v30/n3/full/1300535a.html Protective effects of 9-tetrahydrocannabinol against N-methyl-D-aspartate-induced AF5 cell death (full - 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1824211/?tool=pmcentrez Comparison of Cannabidiol, Antioxidants, and Diuretics in Reversing Binge EthanolInduced Neurotoxicity (full - 2005) http://jpet.aspetjournals.org/content/314/2/780.full In vivo effects of CB1 receptor ligands on lipid peroxidation and antioxidant defense systems in the rat brain of healthy and ethanol-treated rats. (full 2006)
Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: importance of antioxidant and cannabinoid receptor-independent properties. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17196181 Repeated Treatment with Cannabidiol but Not Delta9-tetrahydrocannabinol Has a Neuroprotective Effect Without the Development of Tolerance (abst - 2007)
http://medical-journals.healia.com/doc/17320118/Repeated-treatment-with-cannabidiol-but-not-Delta9tetrahydrocannabinol-has-a-neuroprotective-effect-without-the-development-of-tolerance

(abst - 2007)
77
Cannabidiol in medicine: a review of its therapeutic potential in CNS disorders. (abst - 2008)
The role of the endocannabinoid system in Alzheimer's disease: facts and hypotheses. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18781980 Cannabidiol Attenuates Cisplatin-Induced Nephrotoxicity by Decreasing Oxidative/Nitrosative Stress, Inflammation, and Cell Death (full 2009)
Effect of (-)-Delta(9)-tetrahydrocannabinoid on the hepatic redox state of mice. (full 2010)

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100879X2010007500015&lng=en&nrm=iso&tlng=en
ANXIOLYTIC EFFECTS (anxiety reducing) How Cannabis Compares to other treatments (no date - 2008)
Sedative activity of cannabis in relation to its delta'-trans-tetrahydrocannabinol and cannabidiol content. (full - 1981)
The efficacy and safety of nabilone (a synthetic cannabinoid) in the treatment of anxiety (abst - 1981)
http://www.cannabismed.org/studies/ww_en_db_study_show.php?s_id=229&&search_pattern=ANXIOLYTIC .
Single-dose study of nabilone in anxious volunteers.
(abst - 1981)
http://www.cannabismed.org/studies/ww_en_db_study_show.php?s_id=236&&search_pattern=blood,pressure
78
Antianxiety effect of cannabidiol in the elevated plus-maze.

(abst 1990)
Anxiety with Depression Research Review
(full - 2000) (full - 2001)
http://www.ukcia.org/research/AnxietyWithDepressionResearchReview.pdf
Therapeutic aspects of cannabis and cannabinoids.

http://bjp.rcpsych.org/cgi/content/full/178/2/107
Cannabinoid effects on anxiety-related behaviours and hypothalamic neurotransmitters. (abst - 2001) http://www.ncbi.nlm.nih.gov/pubmed/11566149 Marijuana's Distant Relative May Be The Next Prozac; Chemical Reduces Anxiety Using Novel Nerve System In Body (news - 2002)
Context-dependent effects of CB1 cannabinoid gene disruption on anxiety-like and social behaviour in mice (abst 2004)
http://onlinelibrary.wiley.com/doi/10.1111/j.14609568.2004.03293.x/abstract;jsessionid=15C92BB3498FAF0EE40394675E8B1800.d01t01
Marijuana Eyed for Treatment of Anxiety Disorders
(news - 2004)
http://www.drugfree.org/join-together/drugs/marijuana-eyed-for-treatment
Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects (full - 2005)
http://www.jci.org/cgi/content/full/115/11/3104
Enhancing Cannabinoid Neurotransmission Augments the Extinction of Conditioned Fear (full - 2005) http://www.nature.com/npp/journal/v30/n3/full/1300655a.html Cannabidiol as an antipsychotic. A double-blind, controlled clinical trial on cannabidiol vs. amisulpride in acute schizophrenia. (abst - 2005)
High-dose cannabis stimulates growth of brain cells in rats
(news 2005)
http://www.independent.co.uk/life-style/health-and-families/health-news/highdose-cannabis-stimulatesgrowth-of-brain-cells-in-rats-510869.html
Marijuana might cause new cell growth in the brain

http://www.newscientist.com/article/dn8155
(news 2005)
Endocannabinoids -- The Brain's Cannabis -- Demonstrate Novel Modes Of Action To Stress (news - 2005) http://www.sciencedaily.com/releases/2005/07/050720065810.htm Cannabinoid CB1 Receptor Mediates Fear Extinction via Habituation-Like Processes (full - 2006)
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Delta-9-tetrahydrocannabinol for nighttime agitation in severe dementia

http://science.iowamedicalmarijuana.org/pdfs/neuro/Walther%202006.pdf
(full - 2006)
Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug Anxiolytic-like effect of cannabidiol in the rat Vogel conflict test.
(full - 2006) (abst 2006) (abst 2006)
http://www.scielo.br/scielo.php?pid=S0100-879X2006000400001&script=sci_arttext#Text
Anxiolytic-like properties of the anandamide transport inhibitor AM404.

Modulation of Fear and Anxiety by the Endogenous Cannabinoid System

(full - 2007)
Cannabinoid Modulation of Amygdala Reactivity to Social Signals of Threat in Humans (full - 2008)
The association between anxiety and alcohol versus cannabis abuse disorders among adolescents in primary care settings (full - 2008)
http://fampra.oxfordjournals.org/cgi/content/full/25/5/321
Endocannabinoids: Stress, Anxiety, and Fear
(full - 2009)
http://neuro.psychiatryonline.org/cgi/content/full/21/2/iv?maxtoshow=&hits=80&RESULTFORMAT=&fu lltext=cannabis&searchid=1&FIRSTINDEX=1120&resourcetype=HWCIT
Effects of {Delta}9-tetrahydrocannabinol on reward and anxiety in rats exposed to chronic unpredictable stress. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19406854/abstract/Effects_of_%7BDelta%7D9_tet rahydrocannabinol_on_reward_and_anxiety_in_rats_exposed_to_chronic_unpredictable_stress_
Modulation of effective connectivity during emotional processing by Delta9tetrahydrocannabinol and cannabidiol. (abst - 2009)
http://www.ncbi.nlm.nih.gov/pubmed/19775500?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pub med_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Opposite Effects of Delta-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19924114/full_citation/Opposite_Effects_of_Delta _9_Tetrahydrocannabinol_and_Cannabidiol_on_Human_Brain_Function_and_Psychopathology_
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Cannabidiol reverses the reduction in social interaction produced by low dose Delta(9)tetrahydrocannabinol in rats. (abst 2009) http://www.ncbi.nlm.nih.gov/pubmed/19393686 Brain CB2 Receptors: Implications for Neuropsychiatric Disorders
(full 2010)
Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20829306 Cannabinoids and anxiety. (abst 2010)
A behavioural comparison of acute and chronic Delta9-tetrahydrocannabinol and cannabidiol in C57BL/6JArc mice. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/19785914/abstract/A_behavioural_comparison_of_ acute_and_chronic_Delta9_tetrahydrocannabinol_and_cannabidiol_in_C57BL/6JArc_mice_
Intra-dorsal periaqueductal gray administration of cannabidiol blocks panic-like response by activating 5-HT1A receptors. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20457188/abstract/Intra_dorsal_periaqueductal_gr ay_administration_of_cannabidiol_blocks_panic_like_response_by_activating_5_HT1A_receptors_
Cannabinoids prevent the development of behavioral and endocrine alterations in a rat model of intense stress. (full 2011)
Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-nave social phobia patients. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21307846 Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress. (abst 2011)
Cannabinoids and emotionality: a neuroanatomical perspective.

(abst 2011)
Effect of cannabidiol on sleep disruption induced by the repeated combination tests consisting of open field and elevated plus-maze in rats. (abst 2011)
Anti-Aversive Effects of Cannabidiol on Innate Fear-Induced Behaviors Evoked by an Ethological Model of Panic Attacks Based on a Prey vs the Wild Snake Epicrates cenchria crassus Confrontation Paradigm. (abst - 2011)
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Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report. (abst 2011)
Opposing Roles for Cannabinoid Receptor Type-1 (CB(1)) and Transient Receptor Potential Vanilloid Type-1 Channel (TRPV1) on the Modulation of Panic-Like Responses in Rats. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/21937980
APPETITE STIMULANT also see TASTE, OBESITY Factors influencing the aggressiveness elicited by marihuana in food-deprived rats (full - 1972) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1666002&tool=pmcentrez Marihuana use. Biologic and behavioral aspects.
(abst 1976)
Anorexia and hyperphagia produced by five pharmacologic classes of hallucinogens. (abst 1982) http://www.ncbi.nlm.nih.gov/pubmed/6292959 Behavioral analysis of marijuana effects on food intake in humans.
(abst - 1986)
Effects of smoked marijuana on food intake and body weight of humans living in a residential laboratory. (abst - 1988)
Dronabinol enhancement of appetite in cancer patients. Recent clinical experience with dronabinol.
(abst - 1990)
(abst - 1991) (abst - 1992)
Dronabinol stimulates appetite and causes weight gain in HIV patients.

Dronabinol effects on weight in patients with HIV infection.

(abst - 1992)
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Effect of dronabinol on nutritional status in HIV infection.
(abst - 1993)
A phase II study of delta-9-tetrahydrocannabinol for appetite stimulation in cancerassociated anorexia. (abst - 1994)
Cannabinoids and appetite stimulation.

(abst 1994)
Dronabinol as a treatment for anorexia associated with weight loss in patients with AIDS. (abst - 1995) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=21 The perceived effects of smoked cannabis on patients with multiple sclerosis. (abst - 1997) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=13 Effects of dronabinol on anorexia and disturbed behavior in patients with Alzheimer's disease (abst - 1997) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=59 Immunoactive cannabinoids: Therapeutic prospects for marijuana constituents (full - 2000) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=34030&tool=pmcentrez Low dose anandamide affects food intake, cognitive function, neurotransmitter and corticosterone levels in diet-restricted mice. (abst 2000)
Dietary intake and nutritional status of US adult marijuana users: results from the Third National Health and Nutrition Examination Survey. (full 2001)
http://journals.cambridge.org/action/displayFulltext?type=6&fid=626876&jid=PHN&volumeId=4&issueId =03&aid=562676&bodyId=&membershipNumber=&societyETOCSession=&fulltextType=RA&fileId=S1 368980001000738
Neuroprotection by Delta 9-Tetrahydrocannabinol, the Main Active Compound in Marijuana, against Ouabain-Induced In Vivo Excitotoxicity (full - 2001)
http://www.jneurosci.org/cgi/content/full/21/17/6475?maxtoshow=&hits=10&RESULTFORMAT=&fullte xt=cannabis&andorexactfulltext=and&searchid=1&FIRSTINDEX=50&sortspec=relevance&resourcetype= HWCIT
Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats (full - 2001) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573067/?tool=pmcentrez Therapeutic Aspects of Cannabis and Cannabinoids
http://bjp.rcpsych.org/cgi/reprint/178/2/107.pdf
(full - 2001)
Leptin-regulated endocannabinoids are involved in maintaining food intake (letter 2001) http://www.nature.com/nature/journal/v410/n6830/full/410822a0.html Attack of the munchies (news - 2001)
http://www.newscientist.com/article/dn617-attack-of-the-munchies.html
83
Scientists crack 'munchies' mystery
(news - 2001)
http://news.bbc.co.uk/2/hi/science/nature/1271718.stm
Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2-arachidonoyl glycerol. (full 2002)
The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis (full - 2003)
Endogenous cannabinoid system as a modulator of food intake.

http://www.nature.com/ijo/journal/v27/n3/full/0802250a.html
(full - 2003)
The cannabinoid system: a role in both the homeostatic and hedonic control of eating? (full 2003)
http://journals.cambridge.org/download.php?file=%2FBJN%2FBJN90_04%2FS000711450300179Xa.pdf &code=62ffe5c7ad41131e6dc05fe2f918880a
Safety and efficacy of dronabinol in the treatment of agitation in patients with Alzheimers disease with anorexia: A retrospective chart review (abst - 2003)
Short-term fasting and prolonged semistarvation have opposite effects on 2-AG levels in mouse brain. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12914975 Milk intake and survival in newborn cannabinoid CB1 receptor knockout mice: evidence for a "CB3" receptor. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12568912 Short-term fasting and prolonged semistarvation have opposite effects on 2-AG levels in mouse brain. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12914975 Endocannabinoids: Getting the message across (full - 2004)
Very low doses of delta 8-THC increase food consumption and alter neurotransmitter levels following weight loss. (abst 2004) http://www.ncbi.nlm.nih.gov/pubmed/15099912 Overeating, Alcohol and Sucrose Consumption Decrease in Cb1 Receptor Deleted Mice. (abst 2004)
84
Endocannabinoids and food intake: newborn suckling and appetite regulation in adulthood. (full - 2005) http://ebm.rsmjournals.com/cgi/content/full/230/4/225 Food for thought: endocannabinoid modulation of lipogenesis
http://www.jci.org/articles/view/25076/version/1
(full - 2005) (abst - 2005)
Endocannabinoids in the Regulation of Appetite and Body Weight.
http://medical-journals.healia.com/doc/16148436/Endocannabinoids-in-the-regulation-of-appetite-andbody-weight
Cannabinoids augment the release of neuropeptide Y in the rat hypothalamus (abst 2005) http://www.sciencedirect.com/science/article/pii/S0028390805001668 Effects of the endocannabinoid noladin ether on body weight, food consumption, locomotor activity, and cognitive index in mice. (abst 2005)
THC effective in appetite and weight loss in severe lung disease (COPD)
(news - 2005)
Machinery Of The 'Marijuana Munchies'
(news - 2005)
Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled clinical trial from the Cannabis-InCachexia-Study-Group (full - 2006) http://jco.ascopubs.org/content/24/21/3394.long Effect of a cannabinoid agonist on gastrointestinal transit and postprandial satiation in healthy human subjects: a randomized, placebo-controlled study (abst - 2006)
http://cel.isiknowledge.com/InboundService.do?product=CEL&action=retrieve&SrcApp=Highwire&UT=0 00239661000005&SID=2BiIeEJCIN8n7IfjpEB&Init=Yes&SrcAuth=Highwire&mode=FullRecord&custo mersID=Highwire
Lack of tolerance to the suppressing effect of rimonabant on chocolate intake in rats. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16491428 The synthetic cannabinoid nabilone improves pain and symptom management in cancer patients (abst - 2006)
Methods evaluating cannabinoid and endocannabinoid effects on gastrointestinal functions. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16506408 Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases (abst - 2006)
85
The endogenous cannabinoid system: a new player in the brain-gut-adipose axis (full - 2007) http://www.cannabis-med.org/english/journal/en_2007_02_1.pdf CANNABINOID-INDUCED HYPERPHAGIA: CORRELATION WITH INHIBITION OF PROOPIOMELANOCORTIN NEURONS? (full - 2007)
Pharmacological enhancement of the endocannabinoid system in the nucleus accumbens shell stimulates food intake and increases c-Fos expression in the hypothalamus. (full 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2042935/?tool=pubmed Dronabinol an effective appetite stimulant? (abst - 2007) (abst - 2007)
THC improves appetite and reverses weight loss in AIDS patients

Efficacy of dronabinol alone and in combination with ondansetron versus ondansetron alone for delayed chemotherapy-induced nausea and vomiting. (abst - 2007)
Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep. (abst - 2007) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=190 Feeding induced by cannabinoids is mediated independently of the melanocortin system. (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386290/?tool=pubmed Activating Parabrachial Cannabinoid CB1 Receptors Selectively Stimulates Feeding of Palatable Foods in Rats (full - 2008)
(full 2008)
The role of endocannabinoids in the regulation of gastric emptying: alterations in mice fed a high-fat diet. (full 2008)
ENDOCANNABINOIDS AND THE NEUROCHEMISTRY OF GLUTTONY. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18638022 Behavioral effects of CB2 cannabinoid receptor activation and its influence on food and alcohol consumption. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18991890
86
Role of endocannabinoids and their analogues in obesity and eating disorders. (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/19011363 Endocannabinoids and Their Receptors as Targets for Obesity Therapy (full - 2009)
Synthetic and plant-derived cannabinoid receptor antagonists show hypophagic properties in fasted and non-fasted mice (full - 2009)
Endocannabinoids selectively enhance sweet taste
(full - 2009) (abst 2009) (abst 2009)
Endogenous cannabinoid signalling and energy balance

http://gradworks.umi.com/NR/44/NR44386.html
Cannabinoids and appetite: food craving and food pleasure.

Role of cannabinoid CB1 receptors on macronutrient selection and satiety in rats. (abst 2009) http://www.ncbi.nlm.nih.gov/pubmed/19150453 Natural Pot-Like Compound Could Fight Obesity (news - 2009)
http://www.scientificamerican.com/podcast/episode.cfm?id=natural-pot-like-compound-could-fig-09-12-29
Enhanced Sweet Taste: Endocannabinoids Act Directly on Tongue Taste Receptors (news - 2009) http://www.sciencedaily.com/releases/2009/12/091222104920.htm Chemicals in pot stimulate tongue receptors to taste sweetness. (news - 2009)
http://www.thefreelibrary.com/Chemicals+in+pot+stimulate+tongue+receptors+to+taste+sweetness.a0215089160
The multiple functions of the endocannabinoid system: a focus on the regulation of food intake. (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832623/?tool=pubmed Expression of cannabinoid CB1 receptors by vagal afferent neurons: kinetics and role in influencing neurochemical phenotype (full 2010)
Cannabis constituents modulate 9-tetrahydrocannabinol-induced hyperphagia in rats. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20349049 A nonsynonymous polymorphism in cannabinoid CB2 receptor gene is associated with eating disorders in humans and food intake is modified in mice by its ligands. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/19768813
87
Cannabidiol Attenuates the Appetitive Effects of 9-Tetrahydrocannabinol in Humans Smoking Their Chosen Cannabis (abst - 2010)
http://www.nature.com/npp/journal/vaop/ncurrent/abs/npp201058a.html
Anandamide and AM251, via water, modulate food intake at central and peripheral level in fish. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/19800340 A low-9tetrahydrocannabinol cannabis extract induces hyperphagia in rats. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20975531 Deficiency of CB2 cannabinoid receptor in mice improves insulin sensitivity but increases food intake and obesity with age. (abst 2010)
Endocannabinoid Modulation Of Tongue Sweet Taste Receptors May Help Control Feeding Behavior (news 2010) http://www.medicalnewstoday.com/releases/174683.php Delta-9-tetrahydrocannabinol may palliate altered chemosensory perception in cancer patients: results of a randomized, double-blind, placebo-controlled pilot trial (full 2011) http://annonc.oxfordjournals.org/content/early/2011/02/11/annonc.mdq727.full Cannabidiol inhibits the hyperphagia induced by cannabinoid-1 or serotonin-1A receptor agonists. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21238476 Cannabidiol decreases body weight gain in rats: Involvement of CB2 receptors. (abst - 2011) http://marijuana.researchtoday.net/archive/8/1/3517.htm Efficacy and tolerability of high-dose dronabinol maintenance in HIV-positive marijuana smokers: a controlled laboratory study. (abst 2010)
Science: Cannabis influences blood levels of appetite hormones in people with HIV (news 2011)
Cannabis sativa and the endogenous cannabinoid system: therapeutic potential for appetite regulation. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21213357 The neutral cannabinoid CB receptor antagonist AM4113 regulates body weight through changes in energy intake in the rat. (abst 2011)
Cannabidiol potentiates (9)-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21667074
88
Fish oil promotes survival and protects against cognitive decline in severely undernourished mice by normalizing satiety signals. (abst 2011)
Non-9tetrahydrocannabinol phytocannabinoids stimulate feeding in rats. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22157176 Increment of hypothalamic 2-arachidonoylglycerol induces the preference for a high-fat diet via activation of cannabinoid 1 receptors (abst 2011)
Cannabinoids in children
(abst 2011) (news 2011)
Ingredient in cannabis restores taste for cancer patients
http://news.yahoo.com/s/afp/20110222/hl_afp/healthdiseasecancerdrugscannabisfood
Cannabis Ingredient Can Help Cancer Patients Regain Their Appetites and Sense of Taste, Study Finds (news 2011)
Study helps explain why fatty foods are complicit in weight gain
(news - 2011)
http://www.news-medical.net/news/20110705/Study-helps-explain-why-fatty-foods-are-complicit-inweight-gain.aspx
Endocannabinoid Signaling In Dietary Restriction And Lifespan Extension (news 2011) http://www.medicalnewstoday.com/releases/225007.php Father: Medical marijuana eased pain of my cancer-battling son
(anecdotal 2011)
Smoking marijuana not linked to obesity: study

http://health.yahoo.net/news/s/nm/us_marijuana_obesity
(news 2011)
ARACHIDONYL-2'-CHLOROETHYLAMIDE see ACEA
2-ARACHIDONOYLGLYCEROL see 2-AG
89
ARTHRITIS ANTI-EDEMA AND ANALGESIC PROPERTIES OF 9TETRAHYDROCANNABINOL (THC) (abst- 1973)

http://jpet.aspetjournals.org/content/186/3/646.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=marihuana&searchid=1&FIRSTINDEX=2160&resourcetype=HWCIT
Analgesic and antiinflammatory activity of constituents of Cannabis sativa L. (full - 1988)

US Patent 6132762 - Transcutaneous application of marijuana

http://www.patentstorm.us/patents/6132762/fulltext.html
(full - 2000)
Immunoactive cannabinoids: Therapeutic prospects for marijuana constituents (full - 2000) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=34030&tool=pmcentrez The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis (full - 2000)
Marijuana Extract Helps Arthritis Pain
(news - 2000)
http://www.prohealth.com//library/showArticle.cfm?libid=552
Anandamide activates peripheral nociceptors in normal and arthritic rat knee joints (full - 2001) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1572613/?tool=pmcentrez Cannabidiol-transdermal delivery and anti-inflammatory effect in a murine model. (abst - 2003) http://www.ncbi.nlm.nih.gov/pubmed/14644587 Cannabis May Suppress Immune System (news - 2003)
http://lupus.webmd.com/news/20030415/cannabis-may-suppress-immune-system
A novel synthetic, nonpsychoactive cannabinoid acid (HU-320) with antiinflammatory properties in murine collagen-induced arthritis. (full- 2004)
Ajulemic acid (IP-751): Synthesis, proof of principle, toxicity studies, and clinical trials (abst - 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751505/?tool=pmcentrez Rheumatoid arthritis, Cannabis based medicine eases pain and suppresses disease (news - 2005) http://www.medicalnewstoday.com/articles/33376.php Cannabis could relieve rheumatoid arthritis pain (news - 2005)
http://www.independent.co.uk/life-style/health-and-families/health-news/cannabis-could-relieverheumatoid-arthritis-pain-514536.html
90
Cannabis-Based Drug Relieves Arthritis Pain
(news - 2005)
http://www.medpagetoday.com/Rheumatology/Arthritis/2097
First study to use a cannabis-based medicine for treating rheumatoid arthritis (news - 2005) http://www.news-medical.net/news/2005/11/09/14393.aspx Pot-Based Drug Promising for Arthritis (news - 2005)
http://www.webmd.com/rheumatoid-arthritis/news/20051108/pot-based-drug-promising-for-arthritis
Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis (full - 2006)
http://rheumatology.oxfordjournals.org/cgi/content/full/45/1/50?maxtoshow=&hitqs=80&RESULTFORM AT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=2240&resourcetype=HWCIT
The use of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis (letter - 2006)
http://rheumatology.oxfordjournals.org/cgi/content/full/45/6/781
Arthritis and cannabinoids: HU-210 and Win-55,212-2 prevent IL-1alpha-induced matrix degradation in bovine articular chondrocytes in-vitro. (abst - 2006)
The Cannabinergic System as a Target for Anti-inflammatory Therapies

http://www.ingentaconnect.com/content/ben/ctmc/2006/00000006/00000013/art00008
(abst - 2006)
SAFETY AND TOLERABILITY OF LONG-TERM TREATMENT WITH A CANNABIS-BASED MEDICINE (SATIVEX) IN PATIENTS WITH RHEUMATOID ARTHRITIS (abst - 2006)
http://eular.bmj.com/cgi/content/abstract/65/Suppl_2/498a?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1840 &resourcetype=HWCIT
In vivo effects of CB2 receptor-selective cannabinoids on the vasculature of normal and arthritic rat knee joints (full - 2007)
Arthritis and pain. Future targets to control osteoarthritis pain.

(full - 2007)
INHIBITORY EFFECT OF CANNABINOID AGONISTS ON CYTOKINE PRODUCTION IN HUMAN OSTEOARTRITHIC AND RHEUMATOID FIBROBLAST-LIKE SYNOVIOCYTES (abst - 2007)
http://eular.bmj.com/cgi/content/abstract/66/Suppl_2/283b?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=320& resourcetype=HWCIT
Suppression of fibroblast metalloproteinases by ajulemic acid, a nonpsychoactive cannabinoid acid. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/16927387
91
The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat involves the CB(2) cannabinoid receptor. (abst - 2007)
http://www.unboundmedicine.com/medline/ebm/record/17588560/abstract/The_antinociceptive_effect_of_ Delta9_tetrahydrocannabinol_in_the_arthritic_rat_involves_the_CB_2__cannabinoid_receptor
Synergy between Delta(9)-tetrahydrocannabinol and morphine in the arthritic rat (abst - 2007)
http://www.unboundmedicine.com/medline/ebm/record/17498686/abstract/Synergy_between_Delta_9__tet rahydrocannabinol_and_morphine_in_the_arthritic_rat
Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis. (full - 2008)
Cannabinoid-mediated antinociception is enhanced in rat osteoarthritic knees. (full 2008) http://onlinelibrary.wiley.com/doi/10.1002/art.23156/full CB2 cannabinoid receptor agonist JWH-015 modulates human monocyte migration through defined intracellular signaling pathways. (full 2008)
http://ajpheart.physiology.org/content/294/3/H1145.long
How Cannabis Compares to other treatments
(article - 2008)
Suppression of human macrophage interleukin-6 by a nonpsychoactive cannabinoid acid. (abst - 2008) http://www.ncbi.nlm.nih.gov/sites/pubmed Ajulemic acid, a nonpsychoactive cannabinoid acid, suppresses osteoclastogenesis in mononuclear precursor cells and induces apoptosis in mature osteoclast-like cells. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/17786950 Anti-inflammatory compound from cannabis found in herbs
http://www.rsc.org/chemistryworld/News/2008/June/24060801.asp
(news - 2008)
Cannabinoids as novel anti-inflammatory drugs. How Hemp Seed Oil Can Help Your Arthritis
(full - 2009) (news 2009)
92
Tissue Engineering of Cartilage; Can Cannabinoids Help?

(full 2010)
Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression. (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005548/?tool=pubmed Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain. (full 2010)
Local application of the endocannabinoid hydrolysis inhibitor URB597 reduces nociception in spontaneous and chemically induced models of osteoarthritis. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/21185649/abstract/Local_application_of_the_endo cannabinoid_hydrolysis_inhibitor_URB597_reduces_nociception_in_spontaneous_and_chemically_induce d_models_of_osteoarthritis_
Paradoxical effects of the cannabinoid CB2 receptor agonist GW405833 on rat osteoarthritic knee joint pain. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20863899 Cannabinoids for Treatment of Chronic Non-Cancer Pain; a Systematic Review of Randomized Trials. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21426373 Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21238581 The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55. (abst 2011)
AS- 1535907 synthetic, GPR119 agonist The role of small molecule GPR119 agonist, AS1535907, in glucose-stimulated insulin secretion and pancreatic -cell function (full 2010)
http://pubget.com/search?q=authors%3A%22Y%20Yonetoku%22
Novel GPR119 agonist AS1535907 contributes to first-phase insulin secretion in rat perfused pancreas and diabetic db/db mice. (abst 2010)
93
AS-1907417 synthetic, GPR119 agonist AS1907417, a novel GPR119 agonist, as an insulinotropic and -cell preservative agent for the treatment of type 2 diabetes. (abst 2010)
ASTHMA - also see LUNG FUNCTION Acute effects of smoked marijuana and oral delta-9-tetrahydrocannabinol on specific airway conductance in asthmatic subjects (full - 1974)
http://www.ukcia.org/research/SmokedAndOralInAsthmatic.php
Effects of smoked marijuana in experimentally induced asthma.

http://www.ukcia.org/research/InducedAsthma/index.php
(full - 1975)
Bronchodilator effect of delta1-tetrahydrocannabinol administered by aerosol of asthmatic patients. (full - 1976)

Bronchial effects of aerosolized delta 9-tetrahydrocannabinol

(abst - 1977)
Bronchodilator effect of delta1-tetrahydrocannabinol. (full - 1978) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1429361/ Comparison of bronchial effects of nabilone and terbutaline
(abst - 1983) (abst - 1984) (abst 1986)
Acute and subacute bronchial effects of oral cannabinoids. Role of prostaglandins in marihuana-induced bronchodilation.
ANALGESIC AND ANTIINFLAMMATORY ACTIVITY OF CONSTITUENTS OF CANNABIS SATIVA L. (full - 1988)

Cannabis and cannabinoids: pharmacology and rationale for clinical use

http://pharmgkb.org/pmid/10575283
(abst 1999)

(full - 2001)
94
Endogenous cannabinoid receptor agonists inhibit neurogenic inflammations in guinea pig airways. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/16103691 New Synthetic Delta-9-THC Inhaler Offers Safe, Rapid Delivery
(news - 2005) (abst - 2006)
The Cannabinergic System as a Target for Anti-inflammatory Therapies

Cannabinoid CB(2) receptor activation prevents bronchoconstriction and airway oedema in a model of gastro-oesophageal reflux. (abst - 2007)
(full - 2009)
Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression. (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005548/?tool=pubmed Beneficial effects of cannabinoids (CB) in a murine model of allergen-induced airway inflammation: Role of CB(1)/CB(2) receptors. (abst - 2010)
ATHEROSCLEROSIS Cardiovascular Effects of Cannabis

http://www.idmu.co.uk/canncardio.htm
(news - no date)
Cannabinoids impair the formation of cholesteryl ester in cultured human cells. (full 1981) http://atvb.ahajournals.org/cgi/reprint/1/6/449 Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice. (full - 2005) http://www.nature.com/nature/journal/v434/n7034/full/nature03389.html Cannabis compound tackles blood vessel disease
(news - 2005)
95
Medical marijuana: study shows that THC slows atherosclerosis

http://thenexthurrah.typepad.com/the_next_hurrah/2005/04/medical_marijua.html
(news - 2005) (news - 2005)
Science: THC slows development of atherosclerosis in animal study NOT SO DOPEY (news - 2005)
http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=190#1 http://www.entheology.org/edoto/anmviewer.asp?a=221
Marijuana Chemical Fights Hardened Arteries
(news - 2005) (full - 2006)
http://www.webmd.com/heart-disease/news/20050406/marijuana-chemical-fights-hardened-arteries
Does Cannabis Hold the Key to Treating Cardiometabolic Disease

http://www.nature.com/nrcardio/journal/v3/n3/full/ncpcardio0504.html
Cannabinoid receptors in atherosclerosis.

(abst 2006)
Towards a therapeutic use of selective CB2 cannabinoid receptor ligands for atherosclerosis. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/19804131 The Cannabinergic System as a Target for Anti-inflammatory Therapies
(abst - 2006)
Endocannabinoids and the haematological system
(full - 2007)
Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption (full - 2007)
Cannabinoids and cardiovascular disease: the outlook for clinical treatments. (abst - 2007)
http://www.ncbi.nlm.nih.gov/pubmed/17627561?ordinalpos=1&itool=PPMCLayout.PPMCAppController. PPMCArticlePage.PPMCPubmedRA&linkpos=5
Cannabinoid receptors in acute and chronic complications of atherosclerosis (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219535/?tool=pmcentrez Pleiotropic effects of the CB2 cannabinoid receptor activation on human monocyte migration: implications for atherosclerosis and inflammatory diseases (full 2008)
CB2 cannabinoid receptor agonist JWH-015 modulates human monocyte migration through defined intracellular signaling pathways. (full 2008)
96
Cholesterol-induced stimulation of platelet aggregation is prevented by a hempseedenriched diet. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18418423 The emerging role of the endocannabinoid system in cardiovascular disease (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791499/?tool=pmcentrez Endocannabinoids and the Heart (full - 2009)
Cannabidiol-2',6'-Dimethyl Ether, a Cannabidiol Derivative, Is a Highly Potent and Selective 15-Lipoxygenase Inhibitor. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19406952/abstract/Cannabidiol_2%276%27_Dime thyl_Ether_a_Cannabidiol_Derivative_Is_a_Highly_Potent_and_Selective_15_Lipoxygenase_Inhibitor_
Cannabinoids and atherosclerosis.
(abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19591373/abstract/Cannabinoids_and_atherosclero sis_
US Patent Application 20100158973 - THERAPEUTIC USES OF CANNABIDIOL COMPOUNDS (full 2010) http://www.patentstorm.us/applications/20100158973/fulltext.html WIN55212-2 ameliorates atherosclerosis associated with suppression of proinflammatory responses in ApoE-knockout mice. (abst 2010)
Cannabinoid receptor 2 signaling does not modulate atherogenesis in mice (full 2011)
Cannabinoid Receptor 2 Deficiency in Haematopoietic cells Aggravates Early Atherosclerosis in LDL Receptor Deficient Mice. (full 2011)
Atheroprotection via cannabinoid receptor-2 is mediated by circulating and vascular cells in vivo. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21884703 The effect of dietary hempseed on atherogenesis and contractile function in aortae from hypercholesterolemic rabbits. (abst -2011) http://www.ncbi.nlm.nih.gov/pubmed/21893466
AUTISM THE SAM PROJECT: James D. (news / anecdotal - 2002) (news / anecdotal - 2003)
http://www.letfreedomgrow.com/articles/james_d.htm
Medical marijuana: a valuable treatment for autism?

http://www.autism.com/ari/editorials/ed_marijuana.htm
97
Variations in the human cannabinoid receptor (CNR1) gene modulate striatal responses to happy faces. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16623851 Autism, ADD, ADHD and Marijuana Therapy
(news - 2008) (news 2009)
Does marijuana replace pharmaceuticals as a treatment for Autism?
http://www.examiner.com/special-needs-kids-in-st-petersburg/does-marijuana-replace-pharmaceuticals-asa-treatment-for-autism
Sams Story: Using Medical Cannabis to Treat Autism Spectrum Disorder (news / anecdotal - 2009) http://www.letfreedomgrow.com/cmu/SamsStory.htm Mom: Medical marijuana saved son's life (news / anecdotal - 2009) (news / anecdotal - 2009)
http://abclocal.go.com/kabc/story?section=news/health&id=6989085
The ultimate herbal remedy: Can cannabis improve autism?
http://www.independent.co.uk/life-style/health-and-families/features/the-ultimate-herbal-remedy-cancannabis-improve-autism-1814756.html
Sam's Story: Medical Marijuana and Autism
(news / anecdotal - 2009)
http://www.ktla.com/news/landing/ktla-sweeps-sams-story,0,1396115.story
Use of dronabinol (delta-9-THC) in autism: A prospective single-case-study with an early infantile autistic child (full 2010) http://www.cannabis-med.org/data/pdf/en_2010_04_1.pdf Can autism be triggered by acetaminophen activation of the endocannabinoid system? (link to full 2010) http://www.ane.pl/showarticle.php?art=7026 Steamboat mom sees results from giving autistic son medical marijuana (news/ anecdotal - 2010)
http://www.steamboatpilot.com/news/2010/oct/31/steamboat-mom-sees-results-giving-autistic-son-med/
Why I Give My Autistic Son Pot, Part1 Why I Give My Autistic Son Pot, Part2 Why I Give My 9-Year-Old Pot, Part 3
(news 2010) (news 2010) (news - 2010)

Variation in the human Cannabinoid Receptor (CNR1) gene modulates gaze duration for happy faces. (full 2011) http://www.molecularautism.com/content/pdf/2040-2392-2-10.pdf Consequences of cannabinoid and monoaminergic system disruption in a mouse model of autism spectrum disorders. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21886592
98
Cannabis Science And The Unconventional Foundation For Autism (UF4A) Partner To Advance Successful Cannabis-Based Autism Treatments (news/info-mercial - 2011)
Why I Give My Autistic Son Pot, Part 4

(news 2011) (news 2011)
Wayne Valley alum making a difference in autism research
http://www.northjersey.com/news/119379944_Wayne_Valley_alum_making_a_difference_in_autism_rese arch.html
BACK PAIN - also see PAIN, SPASTICITY, SPINAL CORD INJURY BACK PAIN DUE TO DEGENERATED DISC ANY THERAPEUTIC ROLE OF CANNABIS (abst - 2005)
http://proceedings.jbjs.org.uk/cgi/content/abstract/90-B/SUPP_II/224d?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuana&searchid=1&FIRSTINDEX=320&re sourcetype=HWCIT
Investigational pharmacology for low back pain

`
(full - 2010)
BETA-CARYOPHYLLENE/ (E)-BCP phytocannabinoid, CB2 agonist Beta-caryophyllene is a dietary cannabinoid Anti-inflammatory cannabinoids in diet (full - 2008)
(full - 2008) (full - 2009)

Screening for Antiviral Activities of Isolated Compounds from Essential Oils (full - 2009)
http://ecam.oxfordjournals.org/cgi/content/full/nep187v1?maxtoshow=&hits=10&RESULTFORMAT=&fu lltext=Beta-caryophyllene+&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
-Caryophyllene inhibits dextran sulfate sodium-induced colitis in mice through CB2 receptor activation and PPAR pathway. (abst 2011)
99
BIPOLAR DISORDER The Use of Cannabis as a Mood Stabilizer in Bipolar Disorder: Anecdotal Evidence and the Need for Clinical Research (full - 1998)
http://www.ukcia.org/research/TheUseofCannabisasaMoodStabilizerinBipolarDisorder.html
Recipe For Trouble
(anecdotal/ news - 2002 )
Cannabinoids in bipolar affective disorder: a review and discussion of their therapeutic potential. (full - 2005)
http://www.ukcia.org/research/CannabinoidsInBipolarAffectiveDisorder.pdf
Cannabis in bipolar
(abst - 2005) http://www.pendulum.org/bpnews/archive/001628.html (news - 2005) (news - 2005)
Cannabis Spray for Bipolar
http://www.prohealth.com/me-cfs/blog/boardDetail.cfm?id=565511
Marijuana Could Provide Mental Health Treatments Chemicals in Cannabis may help mentally ill
http://www.drugfree.org/join-together/drugs/marijuana-could-provide
(news - 2005)
Opposite relationships between cannabis use and neurocognitive functioning in bipolar disorder and schizophrenia. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19891810/full_citation/Opposite_relationships_bet ween_cannabis_use_and_neurocognitive_functioning_in_bipolar_disorder_and_schizophrenia_
The effect of extreme marijuana use on the long-term course of bipolar I illness: a single case study. (abst - 2007)
Genetic association between bipolar disorder and 524A>C (Leu133Ile) polymorphism of CNR2 gene, encoding for CB2 cannabinoid receptor. (abst - 2011)
BLADDER / URINARY FUNCTIONS Comparative diuretic activity of delta9-tetrahydrocannabinol, cannabidiol, cannabinol and hydrochlorothiazide in the rat. (abst 1977)
100
Evidence for the presence of cannabinoid CB1 receptors in mouse urinary bladder (abst 1996) http://pharmgkb.org/pmid/8864542 Effects of cannabinoid receptor agonists on neuronally-evoked contractions of urinary bladder tissues isolated from rat, mouse, pig, dog, monkey and human (full - 2000)
Clinical investigation of delta-9-tetrahydrocannabinol (THC) as an alternative therapy for overactive bladders in spinal cord injury (SCI) patients. (abst - 2001)
Contrasting effects of WIN 55212-2 on motility of the rat bladder and uterus. (full 2002) http://www.jneurosci.org/content/22/16/7147.long An open-label pilot study of cannabis-based extracts for bladder dysfunction in advanced multiple sclerosis. (full - 2004)
http://www.ukcia.org/research/CBEForMSBladderDysfunction.pdf
Therapy Insight: Bladder Dysfunction Associated With Multiple Sclerosis

http://www.medscape.com/viewarticle/515091
(full - 2005)
Marijuana-Derived Drug Suppresses Bladder Overactivity And Irritation In Animal Models (news - 2005)
http://www.sciencedaily.com/releases/2005/09/050906080225.htmhttp://www.sciencedaily.com/releases/2 005/09/050906080225.htm

(news - 2006)
Effects of IP-751, ajulemic acid, on bladder overactivity induced by bladder irritation in rats. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17656248 Cannabinoid receptor 2 is increased in acutely and chronically inflamed bladder of rats (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592089/?tool=pmcentrez Distribution and function of cannabinoid receptors 1 and 2 in the rat, monkey and human bladder. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19237169 Incontinence (news - 2009)
http://www.norml.org/index.cfm?Group_ID=7012
Functional role of cannabinoid receptors in urinary bladder

http://www.indianjurol.com/article.asp?issn=09701591;year=2010;volume=26;issue=1;spage=26;epage=35;aulast=Tyagi
(full - 2010)
Cannabinor, a selective cannabinoid-2 receptor agonist, improves bladder emptying in rats with partial urethral obstruction. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/21168864/abstract/Cannabinor_a_selective_cannab inoid_2_receptor_agonist_improves_bladder_emptying_in_rats_with_partial_urethral_obstruction_
101
Effects of cannabinor, a novel selective cannabinoid 2 receptor agonist, on bladder function in normal rats. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20207474 Randomized controlled trial of Sativex to treat detrusor overactivity in multiple sclerosis. (abst 2010) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=314 Local activation of cannabinoid CB1 receptors in the urinary bladder reduces the inflammation-induced sensitization of bladder afferents. (full 2011)
Inhibitory Effect of Standardized Cannabis sativa Extract and Its Ingredient Cannabidiol on Rat and Human Bladder Contractility. (abst 2011)
Cannabinoids: potential targets for bladder dysfunction.

(abst 2011)
Cannabinoid mediated diuresis in mice
(abst 2011)
BLEPHAROSPASM - also see MEIGE'S SYNDROME Open label evaluation of cannabidiol in dystonic movement disorders.
http://web.acsalaska.net/~warmgun/es017.html
(full - 1986)
Cannabinoid agonists in the treatment of blepharospasm--a case report study. (abst - 2004) http://www.ncbi.nlm.nih.gov/pubmed/15159681
BLOOD The inhibitory effects of cannabinoids, the active constituents of Cannabis sativa L. on human and rabbit platelet aggregation. (abst - 1989)
Estrogen stimulates arachidonoylethanolamide release from human endothelial cells and platelet activation (full 2002)
http://bloodjournal.hematologylibrary.org/content/100/12/4040.full
102
The Procoagulatory Effects of Delta-9-Tetrahydrocannabinol in Human Platelets (full - 2004)

http://www.anesthesiaanalgesia.org/content/99/4/1127.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid& searchid=1&FIRSTINDEX=1280&resourcetype=HWCIT
Anticoagulant Effects of a Cannabis Extract in an Obese Rat Model

(abst - 2007)
Cholesterol-induced stimulation of platelet aggregation is prevented by a hempseedenriched diet. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18418423 Circulating endocannabinoid concentrations during orthostatic stress
(abst 2009)
Anandamide extends platelets survival through CB(1)-dependent Akt signaling. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/19936621 Effect of Cannabis sativa on Hematological Indices in Rats and Men (full 2011)
http://docsdrive.com/pdfs/ansinet/pjn/2011/313-316.pdf
BLOOD PRESSURE Reduction by 9-tetrahydrocannabinol in the blood pressure of hypertensive rats bearing regenerated adrenal glands (full - 1973)
Cannabinoids. II. Cardiovascular Effects
(full - 1980)
http://jpet.aspetjournals.org/content/214/1/131.full.pdf+html?ijkey=e751d405c4b7e494c235b602119e4f9b 8c62c04d&keytype2=tf_ipsecsha
Effect of marihuana on intraocular and blood pressure in glaucoma
(full - 1980)
http://www.ukcia.org/research/EffectOnIntraocularAndBloodPressureInGlaucoma.php
The cardiovascular and autonomic effects of repeated administration of delta-9tetrahydrocannabinol to rhesus monkeys. (abst 1981)
Glaucoma, hypertension, and marijuana.
(full - 1982)
103
Body's 'cannabis' could hold blood pressure key

http://www.ukcia.org/research/blood-pressure.php
(news - 1998)

(full - 2000)
Endogenous cannabinoids mediate hypotension after experimental myocardial infarction (full - 2001)
Cardiovascular Effects of Cannabis
(news- 2003) http://www.idmu.co.uk/canncardio.htm
Endocannabinoids Acting at Cannabinoid-1 Receptors Regulate Cardiovascular Function in Hypertension (full - 2004)
Blood pressure regulation by endocannabinoids and their receptors

(full - 2005)
(full - 2005)
Influence of Anandamide, the Endogenous Agonist of Cannabinoid Receptors on the Circulatory System (abst - 2005)
Further Characterization of the Time-Dependent Vascular Effects of 9Tetrahydrocannabinol (full - 2006) http://jpet.aspetjournals.org/content/317/1/428.full The Cannabinoid Cb1 Receptor Antagonist Rimonabant Attenuates the Hypotensive Effect of Smoked Marijuana in Male Smokers. (full 2006)
http://www.ahjonline.com/article/S0002-8703%2805%2901013-6/fulltext
Lowering Of Blood Pressure Achieved Through Use Of Hashish-Like Drug (news - 2006) http://www.sciencedaily.com/releases/2006/06/060620083025.htm
104
Cannabis to lower blood pressure!
(news - 2006) (news 2006)
Marijuana may be Helpful in Lowering Blood Pressure
http://www.bio-medicine.org/medicine-news/Marijuana-may-be-Helpful-in-Lowering-Blood-Pressure11460-1/
The in vitro and in vivo cardiovascular effects of {Delta}9-tetrahydrocannabinol (THC) in rats made hypertensive by chronic inhibition of nitric oxide synthase. (full - 2007)
Characterization of the vasorelaxant mechanisms of the endocannabinoid anandamide in rat aorta (full 2007)
Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190006/?tool=pmcentrez 2-Arachidonylglyceryl ether and abnormal cannabidiol-induced vascular smooth muscle relaxation in rabbit pulmonary arteries via receptor-pertussis toxin sensitive G proteinsERK1/2 signaling. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17292352 Endocannabinoids, blood pressure and the human heart. (full - 2008). (full - 2008)
Modulation of the Endocannabinoid System in Cardiovascular Disease

Triphasic blood pressure responses to cannabinoids: do we understand the mechanism? (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22022923 Increased Blood Pressure Following Abrupt Cessation of Daily Cannabis Use. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21359104 Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21238581 Low-volume binary drug therapy for the treatment of hypovolemia.
(abst 2011)
BONES - see OSTEOPOROSIS
105
BONE MARROW Cannabinoids stimulate fibroblastic colony formation by bone marrow cells indirectly via CB2 receptors. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17205329 Endocannabinoids Are Expressed in Bone Marrow Stromal Niches and Play a Role in Interactions of Hematopoietic Stem and Progenitor Cells with the Bone Marrow Microenvironment (full 2010)
Cannabinoid Receptor 2 Deficiency in Haematopoietic cells Aggravates Early Atherosclerosis in LDL Receptor Deficient Mice (full 2011)
Regulation of hematopoietic stem cell trafficking and mobilization by the endocannabinoid system. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22074629 Cannabinoid receptor 2 and its agonists mediate hematopoiesis and hematopoietic stem and progenitor cell mobilization. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21063029
BOWEL DISORDERS - also see GERD, COLITIS, MARIJUANA AND IRRITABLE BOWEL SYNDROME (IBS) (anecdotal- no date) http://www.rxmarihuana.com/christine.htm Effects of cannabidiol derivatives on intestinal motility (abst - no date)
http://www.docstoc.com/docs/26071658/Effects-of-cannabidiol-derivatives-on-intestinal-motility-
Some actions of delta-1 tetrahydrocannabinol and cannabidiol at cholinergic junctions. (full 1971) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1703324/pdf/brjpharm00552-0217.pdf The effect of cannabinoids on intestinal motility and their antinociceptive effect in mice (full - 1973) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1776598/?tool=pmcentrez&page=1 Intestinal obstruction by an unusual foreign body (full - 1973)
Psychoactive Cannabinoids Reduce Gastrointestinal Propulsion and Motility in Rodents (full - 1989) http://jpet.aspetjournals.org/content/249/2/444.full.pdf+html Marijuana and Crohns Disease (anecdotal - 1997)
http://www.rxmarihuana.com/chrohns3.htm
106
Inhibitory effect of cannabinoid agonists on gastric emptying in the rat

http://www.springerlink.com/content/8fe31unaaat4fbd4/
(abst 1999)
The role of cannabinoid receptors in intestinal motility, defaecation and diarrhoea in rats (abst - 1999) http://www.ncbi.nlm.nih.gov/pubmed/10611417 Central and peripheral cannabinoid modulation of gastrointestinal transit in physiological states or during the diarrhoea induced by croton oil (full - 2000)
Modulation of peristalsis by cannabinoid CB1 ligands in the isolated guinea-pig ileum (full - 2000) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1571902&tool=pmcentrez Inhibition of small intestinal secretion by cannabinoids is CB1 receptor-mediated in rats (abst 2000) http://www.sciencedirect.com/science/article/pii/S0014299900008438 Cannabinoid CB1-mediated inhibition of stress-induced gastric ulcers in rats (abst 2000) http://www.springerlink.com/content/w3jc8rk16k9p92fl/ Cannabinoid CB1-receptor mediated regulation of gastrointestinal motility in mice in a model of intestinal inflammation (full - 2001)
Cannabinoids and the gastrointestinal tract

http://gut.bmj.com/content/48/6/859.full
(full - 2001) (full 2002)
Patent 6410588 Use of cannabinoids as anti-inflammatory agents

Endocannabinoids as physiological regulators of colonic propulsion in mice. (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/12105851 Cannabinoid receptor type 1 modulates excitatory and inhibitory neurotransmission in mouse colon (full 2003)
Cannabinoids for gastrointestinal diseases: potential therapeutic applications (abst - 2003) http://informahealthcare.com/doi/abs/10.1517/13543784.12.1.39 Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation. (full - 2004) http://ajpgi.physiology.org/cgi/content/full/287/1/G7 Cannabinoids and intestinal motility: welcome to CB2 receptors
(full - 2004)
Involvement of cannabinoid receptors in gut motility and visceral perception. (full 2004) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574910/?tool=pubmed
107
Effect of ethanol extracts of three Chinese medicinal plants with laxative properties on ion transport of the rat intestinal epithelia. (full - 2004)
http://www.jstage.jst.go.jp/article/bpb/27/2/162/_pdf
The endogenous cannabinoid system protects against colonic inflammation (full - 2004) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=385396&tool=pmcentrez Cannabinoids cool the intestine (full - 2004)
Involvement of cannabinoid receptors in gut motility and visceral perception (full - 2004) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574910/?tool=pmcentrez Fibromyalgia, IBS, and the Endocannabinoid-CB-Receptor (ECBR) system (abst - 2004) http://www.prohealth.com//library/showArticle.cfm?libid=10562 Cannabinoids spell relief in colon inflammation
(news 2004)
The effects of 9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide (full - 2005)
Effects of cannabinoids on colonic muscle contractility and tension in guinea pigs. (full 2005) http://www.jstage.jst.go.jp/article/jnms/72/1/72_43/_article Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P (full - 2005)
Peripheral, but not central effects of cannabidiol derivatives: mediation by CB(1) and unidentified receptors. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/15910887 Differential Expression of Cannabinoid Receptors in the Human Colon: Cannabinoids Promote Epithelial Wound Healing (abst - 2005)
http://www.gastrojournal.org/article/PIIS0016508505009297/abstract
Cannabis drugs may benefit those with bowel disease

(news - 2005)
Cannabis & inflamed bowel disease
(news - 2005)
108
Cannabis-based drugs could offer new hope for inflammatory bowel disease patients (news - 2005) http://www.medicalnewstoday.com/articles/28584.php Cannabis may soothe inflamed bowels (news - 2005) (news - 2005) (news - 2005)
http://www.chanvre-info.ch/info/en/Cannabis-may-soothe-inflamed.html
Cannabis Alleviates Symptoms of Crohn's Disease

http://ccrmg.org/journal/05aut/chrons.html
Crohn's Patients Report Symptomatic Relief From Cannabis

http://www.thehempire.com/index.php/cannabis/news/4650
Bowel Study Backs Cannabis Drugs
(news - 2005)
http://www.thehempire.com/index.php/cannabis/news/bowel_study_backs_cannabis_drugs
Potential new target for cannabis-derived drugs as a treatment of inflammatory bowel disease (news - 2005) http://www.news-medical.net/news/2005/08/02/12175.aspx Inflammatory Bowel Disease May Respond To Cannabis-Derived Drugs (news - 2005)
http://www.medpagetoday.com/Gastroenterology/InflammatoryBowelDisease/1548
Cannabis-Based Drugs Could Aid in Treating Bowel Disease

http://www.drugfree.org/join-together/drugs/cannabis-based-drugs-could-in
(news - 2005)
Cannabinoid 1 (CB1) receptors coupled to cholinergic motorneurones inhibit neurogenic circular muscle contractility in the human colon. (full 2006)
Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P. (full 2006)
Up-regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation. (full 2006)
Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P (full 2006)
http://gut.bmj.com/content/55/7/946.full
Endocannabinoid overactivity and intestinal inflammation
(full - 2006)
Effects of Cannabinoids on Colonic Muscle Contractility and Tension in Guinea Pigs (full - 2006) http://www.jstage.jst.go.jp/article/jnms/72/1/43/_pdf Endocannabinoids and the gastrointestinal tract. (abst - 2006)
109
Cannabinoids promote survival of normal human colonic epithelial cells (#334) (abst - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1859999/?tool=pmcentrez Effect of a cannabinoid agonist on gastrointestinal transit and postprandial satiation in healthy human subjects: a randomized, placebo-controlled study (abst - 2006)
Methods evaluating cannabinoid and endocannabinoid effects on gastrointestinal functions. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16506408 Science: Cannabinoids reduce inflammation of the bowel in animal model (news - 2006)
Synthetic THC Eases Stomach Cramping, Study Says ACG: Cannabinoid Activator Mellows Out Colon
http://www.medpagetoday.com/MeetingCoverage/ACG/4410
(news - 2006)
http://www.norml.org/index.cfm?Group_ID=7080&wtm_format=print
(news - 2006)
Cannabis Helps Ulcers And Crohn's Disease
(news - 2006) (news - 2006) (news 2006)
http://www.thehempire.com/index.php/cannabis/news/cannabis_helps_ulcers_and_crohns_disease
Cannabis Drugs "May control Symptoms of Gut Disease
http://www.bloomsburycommunications.com/presscentrepdf/bsg_22_03_06_cannabis.pdf
Cannabis Chemicals May Alleviate Post-Eating Stomach Cramps
http://www.bio-medicine.org/medicine-news/Cannabis-Chemicals-May-Alleviate-Post-Eating-StomachCramps-15219-1/
Endocannabinoids and the gastrointestinal tract: what are the key questions? (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190011/?tool=pmcentrez Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon. (full 2007)
The endogenous cannabinoid system: a new player in the brain-gut-adipose axis (full - 2007) http://www.cannabis-med.org/english/journal/en_2007_02_1.pdf Genetic variation in endocannabinoid metabolism, gastrointestinal motility, and sensation (full - 2007)
http://ajpgi.physiology.org/cgi/content/full/294/1/G13?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabinoid&searchid=1&FIRSTINDEX=1120&resourcetype=HWCIT
Effects of a cannabinoid receptor agonist on colonic motor and sensory functions in humans: a randomized, placebo-controlled study (full - 2007)
http://ajpgi.physiology.org/cgi/content/full/293/1/G137
110
Cannabinoid CB2 receptors in the gastrointestinal tract: a regulatory system in states of inflammation (full - 2007)
Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-treated rats. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17396241 The endocannabinoids anandamide and 2-arachidonoylglycerol inhibit cholinergic contractility in the human colon. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17706636 Cannabinoid CB2 receptors in the enteric nervous system modulate gastrointestinal contractility in lipopolysaccharide-treated rats (full - 2008)
Cannabinoid CB2 receptors in the gastrointestinal tract: a regulatory system in states of inflammation. (full 2008)
Genetic variation in endocannabinoid metabolism, gastrointestinal motility, and sensation (full 2008) http://ajpgi.physiology.org/content/294/1/G13.full Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects (full 2008) http://gut.bmj.com/content/57/8/1140.full Effect of 9-tetrahydrocannabinol, a cannabinoid receptor agonist, on the triggering of transient lower oesophageal sphincter relaxations in dogs and humans (full - 2008)
Cannabidiol, extracted from Cannabis sativa, selectively inhibits inflammatory hypermotility in mice (full - 2008)
Cannabinoid CB1 Receptors Are Expressed by Parietal Cells of the Human Gastric Mucosa (full 2008) http://jhc.sagepub.com/content/56/5/511.full The role of endocannabinoids in the regulation of gastric emptying: alterations in mice fed a high-fat diet. (full 2008)
Genetic variation in endocannabinoid metabolism, gastrointestinal motility, and sensation. (full 2008) http://ajpgi.physiology.org/content/294/1/G13.long Anti-inflammatory cannabinoids in diet (full - 2008)
Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects (abst - 2008) http://gut.bmj.com/content/57/8/1140.abstract
111
Cannabinoids and gastrointestinal motility: animal and human studies.
(abst - 2008)
http://www.unboundmedicine.com/medline/ebm/record/18924447/full_citation/Cannabinoids_and_gastroin testinal_motility:_animal_and_human_studies_
The role of the endocannabinoid system in the pathophysiology and treatment of irritable bowel syndrome. (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/18710476 Gastrointestinal endocannabinoid system: multifaceted roles in the healthy and inflamed intestine (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/18671715 Anti-inflammatory compound from cannabis found in herbs
(news - 2008)
Science: THC reduces reflux of acid from the stomach How Cannabis Compares to other treatments
(news 2008)
(news - 2008)
Cannabinoid-1 (CB1) receptors regulate colonic propulsion by acting at motor neurons within the ascending motor pathways in mouse colon (full - 2009)
http://ajpgi.physiology.org/cgi/content/full/296/1/G119?maxtoshow=&hits=80&RESULTFORMAT=&full text=cannabinoid&searchid=1&FIRSTINDEX=160&resourcetype=HWCIT
Interaction between cannabinoid CB1 receptors and endogenous ATP in the control of spontaneous mechanical activity in mouse ileum. (full 2009)
Modulation of motor and sensory pathways of the peristaltic reflex by cannabinoids. (full 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739820/?tool=pubmed Endocannabinoids and the gastrointestinal tract: what are the key questions? (full - 2009) http://www3.interscience.wiley.com/cgi-bin/fulltext/121667871/HTMLSTART Evaluation of prevalent phytocannabinoids in the acetic acid model of visceral nociception (full - 2009)
(full - 2009)
Involvement of nitric oxide in the gastroprotective effect of ACEA, a selective cannabinoid CB1 receptor agonist, on aspirin-induced gastric ulceration. (abst 2009)
Cannabinoids in intestinal inflammation and cancer.
(abst - 2009)
112
Cannabis for Ulcerative Colitis and Crohn's Disease treatment
(news - 2009)
http://www.news-medical.net/news/20091217/Cannabis-for-Ulcerative-Colitis-and-Crohns-Diseasetreatment.aspx
Cannabis Hope for Inflammatory Bowel Disease Gastrointestinal Disorders (news - 2009)
(news - 2009)
The Cannabinoid 1 Receptor (CNR1) 1359 G/A Polymorphism Modulates Susceptibility to Ulcerative Colitis and the Phenotype in Crohn's Disease (full - 2010)
The endocannabinoid system links gut microbiota to adipogenesis

http://www.nature.com/msb/journal/v6/n1/full/msb201046.html
(full - 2010)
Involvement of cannabinoid-1 and cannabinoid-2 receptors in septic ileus. (full 2010)

Cannabinoids and the gut: New developments and emerging concepts.

(abst - 2010)
Pharmacological effects of cannabinoids on the Caco-2 cell culture model of intestinal permeability. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20592049 Gut feelings about the endocannabinoid system (full 2011) (full 2011)
Treatment of Crohn's disease with cannabis: an observational study.

http://www.ima.org.il/imaj/ar11aug-01.pdf
Cannabidiol Reduces Intestinal Inflammation through the Control of Neuroimmune Axis (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232190/?tool=pubmed Efficacy of a Chinese herbal proprietary medicine (Hemp Seed Pill) for functional constipation. (full 2011)
http://www.nature.com/ajg/journal/v106/n1/pdf/ajg2010305a.pdf
Cannabis use amongst patients with inflammatory bowel disease. (abt 2011)
113
Increasing endogenous 2-arachidonoylglycerol levels counteracts colitis and related systemic inflammation. (abst 2011)
Role of cannabinoid receptors and RAGE in inflammatory bowel disease.
(abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21472688/abstract/Role_of_cannabinoid_receptors _and_RAGE_in_inflammatory_bowel_disease_
The endogenous cannabinoid system in the gut of patients with inflammatory bowel disease. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21471961/abstract/The_endogenous_cannabinoid_ system_in_the_gut_of_patients_with_inflammatory_bowel_disease_
Pharmacogenetic Trial of a Cannabinoid Agonist Shows Reduced Fasting Colonic Motility in Patients with Non-Constipated Irritable Bowel Syndrome. (abst 2011)
A novel CB receptor GPR55 and its ligands are involved in regulation of gut movement in rodents. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21726355 Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation. (abst 2011)
Alternative targets within the endocannabinoid system for future treatment of gastrointestinal diseases. (abst 2011)
The effects of cannabidiolic acid and cannabidiol on contractility of the gastrointestinal tract of Suncus murinus. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21975813/abstract/The_effects_of_cannabidiolic_a cid_and_cannabidiol_on_contractility_of_the_gastrointestinal_tract_of_Suncus_murinus_
ENDOGENOUS CANNABINOID SYSTEM REGULATES INTESTINAL BARRIER FUNCTION IN VIVO THROUGH CANNABINOID TYPE 1 RECEPTOR ACTIVATION (abst 2011)
http://ajpgi.physiology.org/content/early/2011/11/28/ajpgi.00158.2011.abstract?sid=d420a7ad-54ba-4946b1da-8bfe664eeec2
Effects of Cannabinoid Agonists on Sheep Sphincter of Oddi in vitro.

(abst 2011)
Inhibition of cannabinoid metabolic enzymes reduces NSAID-induced gastric pathology (abst 2011)
114
Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21745190 Science: Treatment of Crohn's disease with cannabis: an observational study (news 2011)
Surgery REVERSED by Cannabis Oil from vaporizer!

http://medicalmarijuana411.com/mmj411_v3/?p=10687
(anecdotal 2011)
THC Oil Is Saving The Life of My Sister

http://medicalmarijuana411.com/mmj411_v3/?p=10599
(anecdotal 2011)
BRAIN CELLS - see NEURONS
BRAIN - MENTAL EFFECTS - see IQ/COGNITIVE EFFECTS/ MEMORY
BRAIN - PHYSICAL EFFECTS Absence of Cerebral Atrophy in Chronic Cannabis Users. Evaluation by Computerized Transaxial Tomography. (abst 1977)
http://medical-journals.healia.com/doc/576460/Absence-of-cerebral-atrophy-in-chronic-cannabis-users.Evaluation-by-computerized-transaxial-tomography
Computed tomographic examination of heavy marijuana smokers.

(abst 1977)
Neurological and neuroradiological examination of chronic cannabis smokers. (abst 1983) http://www.ncbi.nlm.nih.gov/pubmed/6830182 Chronic Exposure to Delta 9-tetrahydrocannabinol Fails to Irreversibly Alter Brain Cannabinoid Receptors. (abst - 1991)
http://medical-journals.healia.com/doc/1649662/Chronic-exposure-to-delta-9-tetrahydrocannabinol-failsto-irreversibly-alter-brain-cannabinoid-receptors
Changes in cannabinoid receptor binding and mRNA levels in several brain regions of aged rats. (abst 1998) http://www.ncbi.nlm.nih.gov/pubmed/9748581 Effects of frequent marijuana use on brain tissue volume and composition (abst - 1999)
http://www.ukcia.org/research/EffectsOfFrequentMarrijuanaUseOnBrainTissueVolumeAndComposition.ht m
115
Cannabinoid Receptor Messenger Rna Levels Decrease in a Subset of Neurons of the Lateral Striatum, Cortex and Hippocampus of Transgenic Huntington's Disease Mice. (abst - 2000)
http://medical-journals.healia.com/doc/10891614/Cannabinoid-receptor-messenger-RNA-levels-decreasein-a-subset-of-neurons-of-the-lateral-striatum-cortex-and-hippocampus-of-transgenic-Huntingtons-diseasemice
Frequent Marijuana Use May Affect Brain Function But Not Structure
(news - 2000)
Cannabis and the brain. (full - 2003) http://brain.oxfordjournals.org/cgi/content/full/126/6/1252 Non-acute (residual) neurocognitive effects of cannabis use: A meta-analytic study (full - 2003) http://www.hnrc.ucsd.edu/publications_pdf/348art2003.pdf Therapeutic potential of cannabinoids in CNS disease.
(abst - 2003) (abst - 2005)
Lack of hippocampal volume change in long-term heavy cannabis users.

A preliminary DTI study showing no brain structural change associated with adolescent cannabis use (full - 2006)
Astrocytes Implicated In Machinery Of Cannabinoid Signaling

(news 2008) (news 2008) (full- 2009) (abst - 2009)
New brain cells implicated in machinery of cannabinoid signaling

The influence of substance use on adolescent brain development.

Neuroimaging in cannabis use: a systematic review of the literature.
http://www.unboundmedicine.com/medline/ebm/record/19627647/abstract/Neuroimaging_in_cannabis_use :_a_systematic_review_of_the_literature_
Cannabinoid receptors in brain: pharmacogenetics, neuropharmacology, neurotoxicology, and potential therapeutic applications (abst 2009) http://pharmgkb.org/pmid/19897083 White Matter Integrity in Adolescents with Histories of Marijuana Use and Binge Drinking. (abst - 2009)
116
Alterations in the hippocampal endocannabinoid system in diet-induced obese mice. (full 2010) http://www.jneurosci.org/content/30/18/6273.long Disposition of Cannabichromene, Cannabidiol, and 9-Tetrahydrocannabinol and its Metabolites in Mouse Brain following Marijuana Inhalation Determined by HighPerformance Liquid Chromatography-Tandem Mass Spectrometry (abst - 2010)
http://www.ingentaconnect.com/content/pres/jat/2010/00000034/00000008/art00012
Effects of synthetic cannabinoids on electroencephalogram power spectra in rats. (abst 2011)

http://www.unboundmedicine.com/medline/ebm/record/21640532/abstract/Effects_of_synthetic_cannabino ids_on_electroencephalogram_power_spectra_in_rats_
Marijuana Compound Improves Brain And Liver Function In Animal Model Of Hepatic Encephalopathy (news 2011) http://www.norml.org/index.cfm?Group_ID=8464
BRAIN TRAUMA A nonpsychotropic cannabinoid, HU-211, has cerebroprotective effects after closed head injury in the rat. (abst 1993) http://www.ncbi.nlm.nih.gov/pubmed/8411215 Development of HU-211 as a neuroprotectant for ischemic brain damage.
(abst 1995)
45Ca accumulation in rat brain after closed head injury; attenuation by the novel neuroprotective agent HU-211. (abst 1995) http://www.ncbi.nlm.nih.gov/pubmed/7583233 Cytokine production in the brain following closed head injury: dexanabinol (HU-211) is a novel TNF-alpha inhibitor and an effective neuroprotectant. (abst 1997)
How hash became a smash in brain trauma research
(news - 1998)
http://www.maps.org/pipermail/maps_forum/1998-October/001231.html
Exogenous anandamide protects rat brain against acute neuronal injury in vivo. (full 2001) http://www.jneurosci.org/content/21/22/8765.long Brain Injury Circumvented by Endocannabinoids (abst - 2001)
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;2001/104/tw380?maxtoshow=&hits=80&RESULT FORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1680&resourcetype=HWCIT
An endogenous cannabinoid (2-AG) is neuroprotective after brain injury.

(abst - 2001)
117
Cannabinoids on the Brain
(full - 2002) (full - 2002)
http://www.ukcia.org/research/CannabinoidsOnTheBrain.pdf
Cannabinoids and brain injury: therapeutic implications

http://www.ukcia.org/research/CannabinoidsAndBrainInjury.pdf
Dexanabinol (HU-211) in the treatment of severe closed head injury: a randomized, placebo-controlled, phase II clinical trial. (abst - 2002)
Marijuana Smoking Doesn't Kill .
(news - 2003) (abst - 2004)
http://www.webmd.com/smoking-cessation/news/20030918/marijuana-smoking-doesnt-kill
Cannabinoids As Neuroprotective Agents in Traumatic Brain Injury.
http://www.benthamdirect.org/pages/content.php?CPD/2004/00000010/00000018/0007B.SGM
The endocannabinoid 2-AG protects the blood-brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines. (abst - 2005)
The endocannabinoid 2-AG protects the blood-brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines. (abst 2006)
The CB1 Cannabinoid Receptor Mediates Excitotoxicity-induced Neural Progenitor Proliferation and Neurogenesis (full - 2007) http://www.jbc.org/content/282/33/23892.full Endocannabinoids and traumatic brain injury.
(abst 2007)
The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling. (full - 2008) http://www.fasebj.org/cgi/content/full/22/1/285 Cannabinoids as Therapeutic Agents for Ablating Neuroinflammatory Disease (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750822/?tool=pmcentrez Pre- and post-conditioning treatment with an ultra-low dose of 9-tetrahydrocannabinol (THC) protects against pentylenetetrazole (PTZ)-induced cognitive damage. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21315768 N-arachidonoyl-L-serine is neuroprotective after traumatic brain injury by reducing apoptosis (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21505478/abstract/N_arachidonoyl_L_serine_is_n europrotective_after_traumatic_brain_injury_by_reducing_apoptosis_
118
Acute effects of a selective cannabinoid-2 receptor agonist on neuroinflammation in a murine model of traumatic brain injury (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21315768/abstract/Pre__and_post_conditioning_tr eatment_with_an_ultra_low_dose_of_%CE%949_tetrahydrocannabinol__THC__protects_against_pentyle netetrazole__PTZ__induced_cognitive_damage_
Acute effects of a selective cannabinoid-2 receptor agonist on neuroinflammation in a model of traumatic brain injury. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21332427/abstract/Acute_effects_of_a_selective_c annabinoid_2_receptor_agonist_on_neuroinflammation_in_a_murine_model_of_traumatic_brain_injury_
(news 2011)
BREASTFEEDING/ INFANT APPETITE The passage of 14C-delta-9-tetrahydrocannabinol into the milk of lactating squirrel monkeys. (abst 1976) http://www.ncbi.nlm.nih.gov/pubmed/824699 Mammary excretion of cannabidiol in rabbits after intravenous administration. (abst - 1994)
Born with the munchies
(news - 2000)
http://www.newscientist.com/article/mg16722461.600-born-with-the-munchies.html
Critical role of the endogenous cannabinoid system in mouse pup suckling and growth (abst - 2001) http://www.ncbi.nlm.nih.gov/pubmed/11426843 The endocannabinoid system: function in survival of the embryo, the newborn and the neuron. (abst - 2002) http://www.ncbi.nlm.nih.gov/pubmed/12395075 Milk intake and survival in newborn cannabinoid CB1 receptor knockout mice: evidence for a "CB3" receptor. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12568912 Effect of maternal under-nutrition on pup body weight and hypothalamic endocannabinoid levels. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12678501 The endocannabinoid-CB(1) receptor system in pre- and postnatal life.
(abst - 2004)
The endocannabinoid-CB receptor system: Importance for development and in pediatric disease. (abst - 2004) http://www.ncbi.nlm.nih.gov/pubmed/15159678
119
Endocannabinoids and food intake: newborn suckling and appetite regulation in adulthood. (full - 2005)
http://ebm.rsmjournals.com/cgi/content/full/230/4/225?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=cannabinoid&searchid=1&FIRSTINDEX=1040&resourcetype=HWCIT
The cannabinoid system and its importance in the perinatal period

(abst 2005) (full 2006)
Endocannabinoids, feeding and suckling from our perspective

Inhibition of milk ingestion and growth after administration of a neutral cannabinoid CB1 receptor antagonist on the first postnatal day in the mouse. (abst - 2007)
Commentary: Functional Neuronal CB2 Cannabinoid Receptors in the CNS. (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137183/?tool=pubmed Father: Medical marijuana eased pain of my cancer-battling son
(anecdotal 2011)
BULIMIA Association study of cannabinoid receptor gene (CNR1) alleles and anorexia nervosa: differences between restricting and binging/purging subtypes. (abst 2004)
Role of endocannabinoids and their analogues in obesity and eating disorders. (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/19011363 Elevated cannabinoid 1 receptor mRNA is linked to eating disorder related behavior and attitudes in females with eating disorders. (abst 2009)
120
A nonsynonymous polymorphism in cannabinoid CB2 receptor gene is associated with eating disorders in humans and food intake is modified in mice by its ligands. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/19768813 The genetics of eating disorders. (abst 2011)
Brain Type 1 Cannabinoid Receptor Availability in Patients with Anorexia and Bulimia Nervosa. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21718968 Do Deficits in Brain Cannabinoids Contribute to Eating Disorders? (news 2011) http://www.sciencedaily.com/releases/2011/10/111031115226.htm
CANCER BASAL CELL CARCINOMA - see CANCER SKIN
CANCER BLADDER / URETHRAL TRPV2 activation induces apoptotic cell death in human T24 bladder cancer cells: a potential therapeutic target for bladder cancer. (abst 2010)
CANCER - BONE Differential effects of repeated low dose treatment with the cannabinoid agonist WIN 55,212-2 in experimental models of bone cancer pain and neuropathic pain. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18611408 Reduction of bone cancer pain by activation of spinal cannabinoid receptor 1 and its expression in the superficial dorsal horn of the spinal cord in a murine model of bone cancer pain. (full - 2009)
http://journals.lww.com/anesthesiology/Fulltext/2009/07000/Reduction_of_Bone_Cancer_Pain_by_Activat ion_of.31.aspx
Spinal and peripheral analgesic effects of the CB cannabinoid receptor agonist AM1241 in two models of bone cancer-induced pain. (full - 2010)
121
A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20176037 The endocannabinoid system and cancer: therapeutic implication
(full 2011)
Antinociceptive effect of intrathecal cannabinoid receptor agonist WIN 55,212-2 in a rat bone tumor pain model (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21195743/abstract/Antinociceptive_effect_of_intra thecal_cannabinoid_receptor_agonist_WIN_55212_2_in_a_rat_bone_tumor_pain_model_
Antinociceptive effects induced through the stimulation of spinal cannabinoid type 2 receptors in chronically inflamed mice (abst - 2011)
CANCER - BREAST The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation (full - 1998) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC20983/ Suppression of Nerve Growth Factor Trk Receptors and Prolactin Receptors by Endocannabinoids Leads to Inhibition of Human Breast and Prostate Cancer Cell Proliferation (full - 2000) http://endo.endojournals.org/cgi/content/full/141/1/118 Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells (full - 2001)
Antitumor Activity of Plant Cannabinoids with Emphasis on the Effect of Cannabidiol on Human Breast Carcinoma (full - 2006) http://jpet.aspetjournals.org/content/318/3/1375.full 9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer through Cdc2 Regulation (full - 2006) http://cancerres.aacrjournals.org/cgi/content/full/66/13/6615 Cannabinoids As Cancer Hope (article - 2006) (abst - 2006)
Anandamide inhibits adhesion and migration of breast cancer cells.

Cannabidiol inhibits tumour growth in leukaemia and breast cancer in animal studies (news - 2006)
122
A combination of THC and prochlorperazine effective in reducing vomiting in women following breast surgery (news - 2006)
Cannabidiol Dramatically Inhibits Breast Cancer Cell Growth
(news - 2006)
http://www.thehempire.com/index.php/cannabis/news/cannabidiol_dramatically_inhibits_breast_cancer_ce ll_growth_study_says
Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells. (full - 2007) http://mct.aacrjournals.org/content/6/11/2921.long Marijuana Chemical Against Breast Cancer! Cannabis compound 'halts cancer'
(news 2007)
http://news.softpedia.com/news/Marijuana-Chemical-Against-Breast-Cancer-71346.shtml
(news - 2007) (news - 2007)
Cannabis compound stops spread of breast cancer: researchers

http://www.cbc.ca/health/story/2007/11/19/cannabis-cancer.html
Medical Marijuana Takes On New Meaning for Metastatic Breast Cancer (news - 2007) http://www.healthcentral.com/breast-cancer/c/78/16646/takes-cancer/ Cannabidiol may be helpful in reducing the aggressiveness of breast cancer cells (news - 2007) http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=258 Cannabis Compound May Stop Metastatic Breast Cancer (news - 2007) (news - 2007) (news - 2007) (news - 2007)
http://www.washingtonpost.com/wp-dyn/content/article/2007/11/19/AR2007111900834.html
Marijuana Compound Shows Promise In Fighting Breast Cancer

Cannabis compound may stop the spread of breast cancer cells

Cannabis may stop Breast Cancer from spreading in the Body Endocannabinoids in endocrine and related tumours
http://erc.endocrinology-journals.org/cgi/reprint/15/2/391.pdf
http://www.healthjockey.com/2007/11/21/cannabis-may-stop-breast-cancer-from-spreading-in-the-body/
(full - 2008)
The anandamide analog, Met-F-AEA, controls human breast cancer cell migration via the RHOA/RHO kinase signaling pathway. (full 2008)
http://erc.endocrinology-journals.org/cgi/content/full/15/4/965
Design Logic of a Cannabinoid Receptor Signaling Network That Triggers Neurite Outgrowth (full 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776723/?tool=pubmed
123
Delta(9)-tetrahydrocannabinol inhibits 17beta-estradiol-induced proliferation and fails to activate androgen and estrogen receptors in MCF7 human breast cancer cells. (full 2008) http://ar.iiarjournals.org/content/28/1A/85.long JunD is involved in the antiproliferative effect of Delta(9)-tetrahydrocannabinol on human breast cancer cells (abst - 2008)
http://www.knockoutscience.com/showabstract.php?pmid=18454173
Cannabinoid receptor agonists inhibit growth and metastasis of breast cancer (abst - 2008)
http://www.aacrmeetingabstracts.org/cgi/content/meeting_abstract/2008/1_Annual_Meeting/4081?maxtosh ow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=480&resourcety pe=HWCIT
Inhibition of Breast Cancer Aggressiveness by Cannabidiol

http://cbcrp.org.127.seekdotnet.com/research/PageGrant.asp?grant_id=4903
(abst - 2008)
Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer (full - 2009) http://mct.aacrjournals.org/content/8/11/3117.full Phantom breast syndrome. (full 2009) (abst 2009)
Cannabinoids in the treatment of cancer.

Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917429/?tool=pmcentrez Interaction of drugs of abuse and maintenance treatments with human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2). (abst 2010)
A role for L-alpha-lysophosphatidylinositol and GPR55 in the modulation of migration, orientation and polarization of human breast cancer cells. (abst - 2010)
Abstract P1-11-23: Cannabinoid Receptor 2 Compounds in the Attenuation of Breast Cancer Cell Proliferation: Mechanisms of Action (abst 2010)
http://cancerres.aacrjournals.org/cgi/content/meeting_abstract/70/24_MeetingAbstracts/P1-1123?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=400 &sortspec=date&resourcetype=HWCIT
Cannabidiol researchers discover the switch to turn off aggressive breast cancer gene (news - 2010)
http://www.examiner.com/examiner/x-19678-Cannabis-Revolution-Examiner~y2010m3d7-Cannabidiolresearchers-discover-the-switch-to-turn-off-agressive-breast-cancer-gene
124
Medical marijuana news. Cannabidiol stops the spread of breast cancer.
(news - 2010)
http://www.examiner.com/x-19678-Cannabis-Revolution-Examiner~y2010m2d27-Medical-marijuananews--Cannabidiol-stops-the-spread-of-breast-cancer

(full 2011)
Crosstalk between chemokine receptor CXCR4 and cannabinoid receptor CB2 in modulating breast cancer growth and invasion. (full 2011)
Novel hexahydrocannabinol analogs as potential anti-cancer agents inhibit cell proliferation and tumor angiogenesis. (abst 2011)
Cannabidiol induces programmed cell death in breast cancer cells by coordinating the crosstalk between apoptosis and autophagy. (abst 2011)
Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis. (abst 2011)
Omega-3 N-acylethanolamines are endogenously synthesised from omega-3 fatty acids in different human prostate and breast cancer cell lines. (abst 2011)
CANCER - CERVICAL Arachidonyl ethanolamide induces apoptosis of uterine cervix cancer cells via aberrantly expressed vanilloid receptor-1 (full - 2004)
http://science.iowamedicalmarijuana.org/pdfs/cancer/Contassot%202004.pdf
Marijuana Ingredients Slow Invasion by Cervical and Lung Cancer Cells (news - 2007)
http://www.webmd.com/cancer/news/20071226/pot-slows-cancer-in-test-tube
The influence of mast cell mediators on migration of SW756 cervical carcinoma cells. (full 2008) http://www.jstage.jst.go.jp/article/jphs/106/2/106_208/_article Inhibition of Cancer Cell Invasion by Cannabinoids via Increased Expression of Tissue Inhibitor of Matrix Metalloproteinases-1 (full - 2008)
http://jnci.oxfordjournals.org/cgi/content/full/100/1/59
Marijuana use and cervical HPV/neoplasia

http://www.infectagentscancer.com/content/4/S2/P15
(abst - 2008)
125
R(+)-methanandamide-induced apoptosis of human cervical carcinoma cells involves a cyclooxygenase-2-dependent pathway. (abst 2009)
Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19914218 Crosstalk between Chemokine Receptor CXCR4 and Cannabinoid Receptor CB(2) in Modulating Breast Cancer Growth and Invasion. (full 2011)
CANCER CHEMOTHERAPY- see CHEMOTHERAPY
CANCER CHOLANGIOCARCINOMA Opposing Actions of Endocannabinoids on Cholangiocarcinoma Growth

(full - 2007)
The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway (full - 2008)
Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects (full 2008) http://gut.bmj.com/content/57/8/1140.full Opposing actions of endocannabinoids on cholangiocarcinoma growth is via the differential activation of Notch signaling. (full 2010)
Recent advances in the regulation of cholangiocarcinoma growth
(abst - 2010)
http://ajpgi.physiology.org/cgi/content/abstract/299/1/G1?maxtoshow=&hits=80&RESULTFORMAT=&fu lltext=cannabinoid&searchid=1&FIRSTINDEX=1920&resourcetype=HWCIT
The dual effects of delta(9)-tetrahydrocannabinol on cholangiocarcinoma cells: antiinvasion activity at low concentration and apoptosis induction at high concentration. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/19916793 Anandamide exerts its antiproliferative actions on cholangiocarcinoma by activation of the GPR55 receptor. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21464819
126
The novel cannabinoid receptor GPR55, inhibits cholangiocarcinoma growth (abst 2011)
http://www.fasebj.org/cgi/content/meeting_abstract/25/1_MeetingAbstracts/1117.3?maxtoshow=&hits=80 &RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcety pe=HWCIT
CANCER COLON /COLORECTAL Possible endocannabinoid control of colorectal cancer growth. (abst - 2003)
Possible endocannabinoid control of colorectal can... [Gastroenterology. 2003] - PubMed result
Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation. (full - 2004)
Inflammation and Cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation
Anandamide is an endogenous inhibitor for the migration of tumor cells and T lymphocytes. (abst - 2004)
Agonists of cannabinoid receptor 1 and 2 inhibit e... [Am J Physiol Gastrointest Liver Physiol. 2006] PubMed result
The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2
A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells (full 2005)
A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells
Cannabinoids and cancer: potential for colorectal cancer therapy.
(abst - 2005)
Cannabinoids and cancer: potential for colorectal ... [Biochem Soc Trans. 2005] - PubMed result
A cannabinoid quinone inhibits angiogenesis by targeting vascular endothelial cells. (full - 2006) http://molpharm.aspetjournals.org/content/70/1/51.long Opposing Actions of Endocannabinoids on Cholangiocarcinoma Growth : RECRUITMENT OF Fas AND Fas LIGAND TO LIPID RAFTS (full 2007)
The cannabinoid CB(2) receptor: a good friend in the gut.

(abst 2007)
The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17583570
127
Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon. (full 2008)
Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects (full 2008) http://gut.bmj.com/content/57/8/1140.full Cannabinoid receptor activation induces apoptosis through tumor necrosis factor alphamediated ceramide de novo synthesis in colon cancer cells. (full 2008)
http://clincancerres.aacrjournals.org/content/14/23/7691.long
Turned-Off Cannabinoid Receptor Turns On Colorectal Tumor Growth

Turned-off Cannabinoid Receptor Turns On Colorectal Tumor Growth
(news - 2008)
Marijuana takes on colon cancer
(news - 2008) (news - 2008)
Marijuana takes on colon cancer - health - 01 August 2008 - New Scientist
Cannabis-Linked Cell Receptor Might Help Prevent Colon Cancer
HealthScout-Consumer Health News, Information and Resources Updated Daily-Cancer-Cannabis-Linked Cell Receptor Might Help Prevent Colon Cancer
Cannabinoid cell surface receptor plays a tumor-suppressing role in human colorectal cancer (news 2008) http://www.news-medical.net/news/2008/08/03/40485.aspx Induction of the antitumorigenic NSAID-activated gene (NAG-1) in synthetic hexahydrocannabinol-induced apoptosis of human colorectal cancer cells (abst - 2009)
http://www.fasebj.org/cgi/content/meeting_abstract/23/1_MeetingAbstracts/761.5?maxtoshow=&hits=80& RESULTFORMAT=&fulltext=Hexahydrocannabinol&searchid=1&FIRSTINDEX=0&resourcetype=HW CIT
Cannabinoid receptor-independent cytotoxic effects of cannabinoids in human colorectal carcinoma cells: synergism with 5-fluorouracil. (abst + 1st page 2009)
http://www.springerlink.com/content/45008p9643k139l4/
Cannabinoids in intestinal inflammation and cancer

(abst - 2009)
Pharmacological effects of cannabinoids on the Caco-2 cell culture model of intestinal permeability. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20592049 Effects of anandamide on polyamine levels and cell growth in human colon cancer cells (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20682986
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Induction of p53-independent apoptosis by a novel synthetic hexahydrocannabinol analog is mediated via Sp1-dependent NSAID-activated gene-1 in colon cancer cells (abst - 2010) http://www.sciencedirect.com/science/article/pii/S0006295210001735 Involvement of NSAID-activated gene-1 in a novel synthetic hexahydrocannabinol analogue-induced growth inhibition and apoptosis of colon cancer cells (abst - 2010)
The endogenous cannabinoid, anandamide, induces COX-2-dependent cell death in apoptosis-resistant colon cancer cells. (abst, link to PDF - 2010)
http://www.spandidos-publications.com/ijo/37/1/187
Evaluation of the cyclooxygenase inhibiting effects of six major cannabinoids isolated from Cannabis sativa. (full 2011) http://www.jstage.jst.go.jp/article/bpb/34/5/774/_pdf Interaction of endocannabinoid system and steroid hormones in the control of colon cancer cell growth. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21412772 Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22110202 Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/22231745
CANCER - ENDOMETRIAL The Levels of the Endocannabinoid Receptor CB2 and Its Ligand 2Arachidonoylglycerol Are Elevated in Endometrial Carcinoma (full 2010)
http://endo.endojournals.org/content/151/3/921.full
CANCER - GASTRIC Intractable nausea and vomiting due to gastrointestinal mucosal metastases relieved by tetrahydrocannabinol (dronabinol). (abst - 1997)
The effect of cannnabinoid to gastric cancer
(abst - 2006)
http://www.aacrmeetingabstracts.org/cgi/content/abstract/2006/1/958a?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1360 &resourcetype=HWCIT
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Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines. (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/19394652 Effect of a synthetic cannabinoid agonist on the proliferation and invasion of gastric cancer cells. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20336665 Antiproliferative mechanism of a cannabinoid agonist by cell cycle arrest in human gastric cancer cells. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21312237
CANCER GLIOMA (brain cancer) Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells. (full - 1992) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC525583/ Delta9-tetrahydrocannabinol induces apoptosis in C6 glioma cells.
(abst - 1998)
Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. (full - 2000)
http://depts.washington.edu/stellalb/images/Nature2000.pdf
Marijuana's Active Ingredient Targets Deadly Brain Cancer Pot Shrinks Tumors; Government Knew in '74
http://www.alternet.org/story/9257/?page=entire
(news - 2000)
http://www.webmd.com/news/20000228/marijuanas-active-ingredient-targets-deadly-brain-cancer
(news - 2000)
Inhibition of Glioma Growth in Vivo by Selective Activation of the CB2 Cannabinoid Receptor1 (full - 2001) http://cancerres.aacrjournals.org/cgi/reprint/61/15/5784.pdf Inhibition of Rat C6 Glioma Cell Proliferation by Endogenous and Synthetic Cannabinoids. Relative Involvement of Cannabinoid and Vanilloid Receptors (full - 2001) http://jpet.aspetjournals.org/content/299/3/951.full Anti-Tumor Effects (news - 2001) http://www.ukcia.org/research/AntiTumorEffects.htm (full - 2003)
Inhibition of tumor angiogenesis by cannabinoids
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Cannabinoids: Potential Anticancer Agents

http://americanmarijuana.org/Guzman-Cancer.pdf
(full - 2003)
Anti-tumor effects of cannabidiol
(abst - 2003)
http://www.hempworld.com/HempPharm/articles/milanstudy.html
Inhibition of C6 glioma cell proliferation by anandamide, 1-arachidonoylglycerol, and by a water soluble phosphate ester of anandamide: variability in response and involvement of arachidonic acid. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12948856 Up-Regulation of Cyclooxygenase-2 Expression Is Involved in R(_)-MethanandamideInduced Apoptotic Death of Human Neuroglioma Cells (full - 2004)
Cannabinoids Inhibit the Vascular Endothelial Growth Factor Pathway in Gliomas (full - 2004) http://cancerres.aacrjournals.org/cgi/content/full/64/16/5617 Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines. (full - 2004) http://science.iowamedicalmarijuana.org/pdfs/cancer/Massi%202004.pdf Hypothesis: Cannabinoid Therapy for the Treatment of Gliomas? (abst - 2004)
http://medical-journals.healia.com/doc/15275820/Hypothesis-cannabinoid-therapy-for-the-treatment-ofgliomas
Arachidonylethanolamide induces apoptosis of human glioma cells through vanilloid receptor-1. (abst 2004) http://www.ncbi.nlm.nih.gov/pubmed/15453094 Cannabis extract shrinks brain tumours
(news 2004) (news - 2004) (news - 2004) (news - 2004)
'Cannabis' brain tumour drug hope

Marijuana May Stall Brain Tumor Growth
http://www.webmd.com/cancer/news/20040815/marijuana-stall-brain-tumor-growth
Marijuana Extract Fights Brain Cancer in Mice Cancer Killer
http://www.scientificamerican.com/article.cfm?id=marijuana-extract-fights
(news - 2004) http://www.november.org/stayinfo/breaking2/CancerKiller.html
Marijuana Ingredient Inhibits VEGF Pathway Required For Brain Tumor Blood Vessels (news - 2004) http://www.sciencedaily.com/releases/2004/08/040816085401.htm Cannabis extract makes brain tumors shrink, halts growth of blood vessels (news - 2004) http://www.medicalnewstoday.com/articles/12088.php
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Cannabidiol inhibits human glioma cell migration through a cannabinoid receptorindependent mechanism (full - 2005)
Endocannabinoid metabolism in human glioblastomas and meningiomas compared to human non-tumour brain tissue (full - 2005)
http://www.ukcia.org/research/EndocannabinoidMetabolismInHumanGlioblastomasAndMeningiomas.pdf
Cannabinoids selectively inhibit proliferation and induce death of cultured human glioblastoma multiforme cells. (abst - 2005)
Effects on cell viability.
(abst 2005)
A pilot clinical study of Delta(9)-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme. (full - 2006)
The non-psychoactive Cannabidiol triggers caspase activation and oxidative stress in human glioma cells. (abst - 2006)
http://www.ihop-net.org/UniPub/iHOP/pm/12214911.html?pmid=16909207
Acyl-based anandamide uptake inhibitors cause rapid toxicity to C6 glioma cells at pharmacologically relevant concentrations. (abst 2006)
R(+)-methanandamide elicits a cyclooxygenase-2-dependent mitochondrial apoptosis signaling pathway in human neuroglioma cells. (abst 2006)
http://www.springerlink.com/content/l403431l1728x733/
Safety and efficacy of a novel cannabinoid chemotherapeutic, KM-233, for the treatment of high-grade glioma. (abst 2006) http://www.springerlink.com/content/75pu360830261968/ Cannabinoids Curb Brain Tumor Growth, First-Ever Patient Trial Shows (news 2006)
THC tested against brain tumour in pilot clinical study
(news - 2006)
Cannabinoids Induce Glioma Stem-like Cell Differentiation and Inhibit Gliomagenesis (full - 2007) http://www.jbc.org/content/282/9/6854.long Expression of cannabinoid receptors and neurotrophins in human gliomas.
(abst - 2007)
Targeting astrocytomas and invading immune cells with cannabinoids: a promising therapeutic avenue. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17952648
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Cannabinoids and gliomas.
(abst - 2007) (news 2007) (full - 2008)
New Study: Marijuana Might Cure Brain Tumors
http://stopthedrugwar.org/speakeasy/2007/oct/18/new_study_marijuana_might_cure_b
Cannabinoids as potential new therapy for the treatment of gliomas

http://safeaccess.ca/research/pdf/ParolaroCBasTherapyforGliomas2008.pdf
US Patent Application 20080262099 - Inhibition of Tumour Cell Migration (full 2008) http://www.patentstorm.us/applications/20080262099/fulltext.html Cannabinoids Inhibit Glioma Cell Invasion by Down-regulating Matrix Metalloproteinase-2 Expression (full - 2008)
http://cancerres.aacrjournals.org/cgi/content/full/68/6/1945
Delta 9-tetrahydrocannabinol inhibits cell cycle progression by downregulation of E2F1 in human glioblastoma multiforme cells. (abst - 2008)
Down-regulation of tissue inhibitor of metalloproteinases-1 in gliomas: a new marker of cannabinoid antitumoral activity? (abst - 2008)
5-Lipoxygenase and anandamide hydrolase (FAAH) mediate the antitumor activity of cannabidiol, a non-psychoactive cannabinoid. (abst 2008)
High concentrations of cannabinoids activate apoptosis in human U373MG glioma cells. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18615640 Marijuana Kills Brain Cancer Cells (news - 2008)
Cannabinoid action induces autophagymediated cell death through stimulation of ER stress in human glioma cells. (full - 2009)
TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action.

http://www.landesbioscience.com/journals/autophagy/SalazarAUTO5-7.pdf
(full 2009)
Amphiregulin is a factor for resistance of glioma cells to cannabinoid-induced apoptosis (abst 2009) http://www.ncbi.nlm.nih.gov/pubmed/19229996 THC initiates brain cancer cells to destroy themselves Marijuana ingredient may reduce tumours-study
http://www.alertnet.org/thenews/newsdesk/LV470563.htm
(news - 2009)
http://www.worldhealth.net/news/thc_initiates_brain_cancer_cells_to_dest/
(news - 2009)
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Active Ingredient in Marijuana Kills Brain Cancer Cells
(news - 2009)
http://health.usnews.com/health-news/family-health/cancer/articles/2009/04/01/active-ingredient-inmarijuana-kills-brain-cancer.html
Marijuana Chemical May Fight Brain Cancer
(news - 2009)
http://www.webmd.com/cancer/brain-cancer/news/20090401/marijuana-chemical-may-fight-brain-cancer
Active Component Of Marijuana Has Anti-Cancer Effects, Study Suggests (news - 2009) http://www.sciencedaily.com/releases/2009/04/090401181217.htm Anti-Cancer Effects In Active Component Of Marijuana
(news 2009)
Cannabidiol Enhances the Inhibitory Effects of 9-Tetrahydrocannabinol on Human Glioblastoma Cell Proliferation and Survival (full - 2010)
http://www.letfreedomgrow.com/cmu/Brain_Cancer_Study.pdf
The expression level of CB1 and CB2 receptors determines their efficacy at inducing apoptosis in astrocytomas. (full - 2010)
Cannabinoid and cannabinoid-like receptors in microglia, astrocytes, and astrocytomas. (full 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919281/?tool=pubmed Opposite changes in cannabinoid CB1 and CB2 receptor expression in human gliomas. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20307616 Cannabinoids inhibit glioma cell invasion in brain cancer studies (news - 2010)
http://www.examiner.com/x-19678-Cannabis-Revolution-Examiner~y2010m3d11-Cannabinoids-inhibitglioma-cell-invasion-in-brain-cancer-studies
Cannabis Rx: Cutting Through the Misinformation : Dr. Andrew Weil Cannabis Inhalation Associated With Spontaneous Tumor Regression (news - 2010)
(news - 2010)
http://www.huffingtonpost.com/andrew-weil-md/can-cannabis-treat-cancer_b_701005.html
http://blog.norml.org/2011/03/22/cannabis-inhalation-associated-with-spontaneous-tumor-regression-studysays/
Molecular Mechanisms Involved in the Antitumor Activity of Cannabinoids on Gliomas: Role for Oxidative Stress (abst/ click for full PDF 2011)
http://www.mdpi.com/2072-6694/2/2/1013/
Spontaneous regression of septum pellucidum/forniceal pilocytic astrocytomas-possible role of Cannabis inhalation. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21336992 A combined preclinical therapy of cannabinoids and temozolomide against glioma. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21220494
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Stimulation of the midkine/ALK axis renders glioma cells resistant to cannabinoid antitumoral action. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21233844 Marijuana Compound Induces Cell Death In Hard-To-Treat Brain Cancer (news 2011) http://www.norml.org/index.cfm?Group_ID=8459 Inhaled Cannabis May Keep Brain Cancer in Remission (news 2011)
http://www.freedomisgreen.com/inhaled-marijuana-may-keep-brain-cancer-in-remission/
CANCER - HEAD AND NECK Marijuana Unlikely to Cause Head, Neck, or Lung Cancer Marijuana use and Risk of Oral Squamous Cell Carcinoma
http://cancerres.aacrjournals.org/content/64/11/4049.full
(news - 2000) (full - 2004) (full - 2008)
http://www.webmd.com/smoking-cessation/news/20000508/marijuana-unlikely-to-cause-cancer
Cannabis use and cancer of the head and neck: Case-control study
A population-based case-control study of marijuana use and head and neck squamous cell carcinoma. (full 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812803/?tool=pubmed Marijuana May Reduce Risk of Certain Cancers, Study Says
http://www.drugfree.org/uncategorized/marijuana-may-reduce-risk-of
(news - 2009)
CANCER - KAPOSI'S SARCOMA THC inhibits lytic replication of gamma oncogenic herpes viruses in vitro
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=521080
(full - 2004)
The CB1/CB2 receptor agonist WIN-55,212-2 reduces viability of human Kaposis sarcoma cells in vitro (full - 2009)
http://science.iowamedicalmarijuana.org/pdfs/cancer/Luca%20et%20al%202009%2019539619.pdf
Recreational Drug Use and Risk of Kaposi's Sarcoma in HIV- and HHV-8-Coinfected Homosexual Men (full - 2009)
135
CANCER KIDNEY Cannabinoid CB1 Receptor Is Downregulated in Clear Cell Renal Cell Carcinoma (full - 2010) http://jhc.sagepub.com/content/58/12/1129.long
CANCER - LEUKEMIA Effects of cannabinoids on L1210 murine leukemia. 1. Inhibition of DNA synthesis. (abst - 1977)
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=897352&dopt=abstractp lus
Cannabinoids induce incomplete maturation of cultured human leukemia cells (full - 1987) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC298868/?tool=pmcentrez&page=1 Fatal aspergillosis associated with smoking contaminated marijuana, in a marrow transplant recipient. (full - 1988) http://chestjournal.chestpubs.org/content/94/2/432.long Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors (full - 2000) http://www.jbc.org/content/275/41/31938.full Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease (full - 2002) http://bloodjournal.hematologylibrary.org/cgi/reprint/100/2/627.pdf Gamma-irradiation enhances apoptosis induced by cannabidiol, a non-psychotropic cannabinoid, in cultured HL-60 myeloblastic leukemia cells. (abst - 2003)
Cannabis-induced cytotoxicity in leukemic cell lines: the role of the cannabinoid receptors and the MAPK pathway (full - 2005)
http://bloodjournal.hematologylibrary.org/cgi/content/full/105/3/1214
Marijuana's Active Ingredient Kills Leukemia Cells
(forum post/news - 2005)
http://www.treatingyourself.com/vbulletin/showthread.php?t=7107
Cannabidiol-Induced Apoptosis in Human Leukemia Cells : A Novel Role of Cannabidiol in the Regulation of p22phox and Nox4 Expression (full - 2006)
http://molpharm.aspetjournals.org/cgi/content/full/70/3/897
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{Delta}9-Tetrahydrocannabinol-Induced Apoptosis in Jurkat Leukemia T Cells Is Regulated by Translocation of Bad to Mitochondria (full - 2006)
http://mcr.aacrjournals.org/content/4/8/549.full
Is there a temperature-dependent uptake of anandamide into cells?

( full 2006)
Parental marijuana use and risk of childhood acute myeloid leukaemia: a report from the Children's Cancer Group (United States and Canada). (abst 2006)
The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells. (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16458258 Cannabis destroys cancer cells (news - 2006)
Cannabidiol inhibits tumour growth in leukaemia and breast cancer in animal studies (news - 2006)
HU-331, a novel cannabinoid-based anticancer topoisomerase II inhibitor

http://mct.aacrjournals.org/content/6/1/173.long
(full - 2007)
Medical Marijuana Use and Research Leukemia & Lymphoma Society Statement (full 2008) http://www.maps.org/mmj/lnls-res.pdf Enhancing the in vitro cytotoxic activity of Delta9-tetrahydrocannabinol in leukemic cells through a combinatorial approach (abst - 2008)
Substance use and survival after treatment for chronic myelogenous leukemia (CML) or myelodysplastic syndrome (MDS). (full - 2010)
Cannabidiol induced a contrasting pro-apoptotic effect between freshly isolated and precultured human monocytes. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/20471992/abstract/Cannabidiol_induced_a_contras ting_pro_apoptotic_effect_between_freshly_isolated_and_precultured_human_monocytes_
CANCER LIVER Overexpression of cannabinoid receptors CB1 and CB2 correlates with improved prognosis of patients with hepatocellular carcinoma. (abst 2006)
137
Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects (full 2008) http://gut.bmj.com/content/57/8/1140.full Apoptosis induced in HepG2 cells by the synthetic cannabinoid WIN: involvement of the transcription factor PPARgamma. (abst 2009)
The synthetic cannabinoid WIN 55,212-2 sensitizes hepatocellular carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by activating p8/CCAAT/enhancer binding protein homologous protein (CHOP)/death receptor 5 (DR5) axis. (full 2010) http://molpharm.aspetjournals.org/content/77/5/854.long The effect of the activation of cannabinoid receptor on the proliferation and apoptosis of hepatoma HepG2 cells (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20368112 Membrane cholesterol mediates the endocannabinoids-anandamide affection on HepG2 cells (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20380798 Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPKdependent activation of autophagy. (abst 2011)
CANCER - LUNG A pilot study of orally administered 1-trans-tetrahydrocannabinol in the management of patients undergoing radiotherapy for carcinoma of the bronchus (full - 1974)
Anticancer activity of cannabinoids
(full - 1975) (full - 1975)
http://drugpolicycentral.com/bot/pg/cancer/THC_cancer_sep_1975.htm
Antineoplastic activity of cannabinoids
http://www.ukcia.org/research/AntineoplasticActivityOfCannabinoids/default.html
In vivo effects of cannabinoids on macromolecular biosynthesis in Lewis lung carcinomas. (abst - 1977) http://www.ncbi.nlm.nih.gov/pubmed/616322 Anti-emetic efficacy and toxicity of nabilone, a synthetic cannabinoid, in lung cancer chemotherapy. (full - 1983)
No increase in carcinogen-DNA adducts in the lungs of monkeys exposed chronically to marijuana smoke. (abst 1992) http://www.ncbi.nlm.nih.gov/pubmed/1488780
138
Marijuana Less Harmful to Lungs than Cigarettes

http://www.ukcia.org/research/lungs.php
(news - 1994) (news 1999) (news - 2000)
So, you thought it was the tar that caused cancer...

http://www.ukcia.org/research/cancer2.php
Marijuana Unlikely to Cause Head, Neck, or Lung Cancer Anti-Tumor Effects
http://www.webmd.com/smoking-cessation/news/20000508/marijuana-unlikely-to-cause-cancer
(news - 2001) http://www.ukcia.org/research/AntiTumorEffects.htm
Cannabis and tobacco smoke are not equally carcinogenic. (full 2005)
Smoking Cannabis Does Not Cause Cancer of Lung or Upper Airways

http://ccrmg.org/journal/05aut/nocancer.html
(news - 2005) (news - 2005)
Cannabis Smoke Is Less Likely To Cause Cancer Than Tobacco Smoke

Marijuana Use and the Risk of Lung and Upper Aerodigestive Tract Cancers: Results of a Population-Based Case-Control Study (full - 2006)
http://cebp.aacrjournals.org/content/15/10/1829.full
Marijuana Use and Lung Cancer: Results of a Case-Control Study

http://www.ukcia.org/research/MjUseAndLungCancer.php
(abst - 2006) (news - 2006)
Study Finds No Link Between Marijuana Use And Lung Cancer

Study Finds No Cancer-Marijuana Connection
(news 2006)
http://www.washingtonpost.com/wp-dyn/content/article/2006/05/25/AR2006052501729_pf.html
No association between lung cancer and cannabis smoking in large study (news - 2006)
Marijuana Smoking Found Non-Carcinogenic Pot Smoking Not Linked to Lung Cancer
(news - 2006)
http://www.medpagetoday.com/HematologyOncology/LungCancer/tb/3393
(news - 2006) (news - 2006) (news 2006)
Large Study Finds No Link between Marijuana and Lung Cancer

http://www.scientificamerican.com/article.cfm?id=large-study-finds-no-link
There Seems to Be No Link between Marijuana Use and Lung Cancer
http://news.softpedia.com/news/There-Seems-to-Be-No-Link-between-Marijuana-Use-and-Lung-Cancer24575.shtml
139
{Delta}-9 Tetrahydrocannabinol inhibits growth and metastasis of lung cancer. (abst - 2007)
http://www.aacrmeetingabstracts.org/cgi/content/meeting_abstract/2007/1_Annual_Meeting/4749?maxtosh ow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1760&resourcet ype=HWCIT
Marijuana Cuts Lung Cancer Tumor Growth In Half, Study Shows

(news 2007) (news - 2007)
Pot's Active Ingredient Halts Lung Cancer Growth, Study Says

http://www.illinoisnorml.org/content/view/529/27/
Marijuana Ingredients Slow Invasion by Cervical and Lung Cancer Cells (news - 2007) http://www.webmd.com/cancer/news/20071226/pot-slows-cancer-in-test-tube Marijuana Helps to Combat Lung Cancer Marijuana May Fight Lung Tumors (news 2007)
http://www.bio-medicine.org/medicine-news/Marijuana-Helps-to-Combat-Lung-Cancer-20045-1/
(news - 2007) (news - 2007) (news 2007)
http://www.webmd.com/lung-cancer/news/20070417/marijuana-may-fight-lung-tumors
Cannabis as a possible treatment for lung cancer
http://arstechnica.com/science/news/2007/04/cannabis-as-a-possible-treatment-for-lung-cancer.ars
Marijuana Beneficial in Fighting Lung Tumors, Study
http://www.bio-medicine.org/medicine-news/Marijuana-Beneficial-in-Fighting-Lung-Tumors--Study20037-1/
Inhibition of Cancer Cell Invasion by Cannabinoids via Increased Expression of Tissue Inhibitor of Matrix Metalloproteinases-1 (full - 2008)
Doubts about the role of cannabis in causing lung cancer.

http://erj.ersjournals.com/cgi/content/full/32/3/815
(letter - 2008)
Delta9-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo. (abst 2008)
Decrease of plasminogen activator inhibitor-1 may contribute to the anti-invasive action of cannabidiol on human lung cancer cells. (abst - 2010)
Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19914218
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Medical Marijuana; The active ingredient in marijuana cuts tumor growth in common lung cancer in half and significantly reduces the ability of the cancer to spread, say researchers at Harvard University. (news 2010)
http://www.thefreelibrary.com/Medical+Marijuana%3b+The+active+ingredient+in+marijuana+cuts+tumor ...-a0243683610
Effects of smoking cannabis on lung function

http://www.expert-reviews.com/doi/full/10.1586/ers.11.40
(full 2011)
Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non-small cell lung cancer growth and metastasis (full - 2011)
Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22198381
CANCER - LYMPHOMA UCSF Researchers Report New Risk Factors For Non-Hodgkin's Lymphoma (news - 1999) http://www.sciencedaily.com/releases/1999/08/990817065339.htm Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors (full - 2000) http://www.jbc.org/content/275/41/31938.full Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease (full - 2002) http://bloodjournal.hematologylibrary.org/cgi/content/full/100/2/627 Lymphoma may be slowed by cannabis (news - 2002)
http://marijuana-ro.com/medical-usage/lymphoma-may-be-slowed-by-cannabis.html
Cannabinoid Receptor Agonists May Be Novel Class of Anti-Lymphoma Agents (news - 2002)
http://www.oncolink.org/resources/article.cfm?c=3&s=8&ss=23&Year=2002&Month=7&id=8667
High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma (abst 2003)
141
Cannabinoid receptor ligands mediate growth inhibition and cell death in mantle cell lymphoma. (abst - 2005) http://www.ncbi.nlm.nih.gov/pubmed/16337199?dopt=Abstract Cannabinoid Receptor-Mediated Apoptosis Induced by R(+)-Methanandamide and Win55,212-2 Is Associated with Ceramide Accumulation and p38 Activation in Mantle Cell Lymphoma (full - 2006) http://molpharm.aspetjournals.org/content/70/5/1612.full The expression of the peripheral cannabinoid receptor on cells of the immune system and non-Hodgkin's lymphomas. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17613768 Medical Marijuana Use and Research Leukemia & Lymphoma Society Statement (full 2008) http://www.maps.org/mmj/lnls-res.pdf Expression of cannabinoid receptors type 1 and type 2 in non-Hodgkin lymphoma: growth inhibition by receptor activation. (abst - 2008)
Cannabis Agonist Reduces Non-Hodgkin Lymphoma Tumor Growth, says study (news - 2008) http://www.illinoisnorml.org/content/view/957/27/ Potentiation of cannabinoid-induced cytotoxicity in mantle cell lymphoma through modulation of ceramide metabolism. (full - 2009)
http://mcr.aacrjournals.org/content/7/7/1086.long
WIN55,212-2 induces cytoplasmic vacuolation in apoptosis-resistant MCL cells. (full 2011) http://www.nature.com/cddis/journal/v2/n11/full/cddis2011106a.html
CANCER - MELANOMA Intractable nausea and vomiting due to gastrointestinal mucosal metastases (abst - 1997)
Cannabinoid receptors as novel targets for the treatment of melanoma
(full - 2006)
http://www.fasebj.org/cgi/content/full/20/14/2633?ijkey=958a31584b617c871b46ef1af541c90cc0fb0f14
Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases. (abst - 2006)
Cannabinoid receptor-1 modulation induces apoptosis of human melanoma cells (abst - 2008)
142
Inhibition of basal and ultraviolet B-induced melanogenesis by cannabinoid CB(1) receptors: a keratinocyte-dependent effect. (abst 2011)
The antimitogenic effect of the cannabinoid receptor agonist WIN55212-2 on human melanoma cells is mediated by the membrane lipid raft. (abst 2011)
CANCER - NEUROBLASTOMA Inhibition of neuroblastoma adenylate cyclase by cannabinoid and nantradol compounds (abst 1984) http://www.ncbi.nlm.nih.gov/pubmed/6090851 Cannabinoid inhibition of adenylate cyclase. Biochemistry of the response in neuroblastoma cell membranes. (abst 1985) http://www.ncbi.nlm.nih.gov/pubmed/2984538 Interaction of delta-9-tetrahydrocannabinol with rat B103 neuroblastoma cells. (abst 1987) http://www.ncbi.nlm.nih.gov/pubmed/2821958 Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells. (full - 1992) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC525583/ Cannabinoid receptor agonists inhibit Ca current in NG108-15 neuroblastoma cells via a pertussis toxin-sensitive mechanism. (full - 1992)
Stimulation of anandamide biosynthesis in N-18TG2 neuroblastoma cells by delta 9tetrahydrocannabinol (THC). (abst 1995) http://www.ncbi.nlm.nih.gov/pubmed/7702643 Potential biosynthetic connections between the two cannabimimetic eicosanoids, anandamide and 2-arachidonoyl-glycerol, in mouse neuroblastoma cells. (abst 1996)
Tau protein after delta-9-tetrahydrocannabinol in a human neuroblastoma cell line. (abst 1996) http://www.ncbi.nlm.nih.gov/pubmed/8981058 Anandamide Induces Apoptosis in Human Cells via Vanilloid Receptors (full - 2000)
A predominant role for inhibition of the adenylate cyclase/protein kinase A pathway in ERK activation by cannabinoid receptor 1 in N1E-115 neuroblastoma cells. (full 2003) http://www.jbc.org/content/278/49/48973.long
143
CANCER - ORAL Boron trifluoride etherate on silica-A modified Lewis acid reagent (VII). Antitumor activity of cannabigerol against human oral epitheloid carcinoma cells. (abst - 1998)
Marijuana use and Risk of Oral Squamous Cell Carcinoma

(full - 2004)
Study Finds No Association Between Marijuana Use And Incidence Of Oral Cancer (news - 2004) http://www.sciencedaily.com/releases/2004/06/040602063428.htm Smoking of cannabis does not increase risk for oral cancer (news - 2004)
Peripheral Cannabinoids Attenuate Carcinoma Induced Nociception in Mice (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771220/ A Population-Based Case-Control Study of Marijuana Use and Head and Neck Squamous Cell Carcinoma. (full - 2009)
http://safeaccess.ca/research/pdf/MarijuanaUse_and_Head-NeckSquamousCellCarcinoma.pdf
Cannabinoids Inhibit Cellular Respiration of Human Oral Cancer Cells

(full - 2010)
Cannabinoids attenuate cancer pain and proliferation in a mouse model. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21094209
144
CANCER - OVARIAN Cannabinoid receptors as a target for therapy of ovarian cancer (abst - 2006)
http://www.aacrmeetingabstracts.org/cgi/content/abstract/2006/1/1084?maxtoshow=&hits=80&RESULTF ORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=560&resourcetype=HWCIT
The putative cannabinoid receptor GPR55 defines a novel autocrine loop in cancer cell proliferation. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/20838378
CANCER - PANCREATIC Pancreatitis & Medical Marijuana (article - no date)

http://onlinepot.org/medical/pancreatitis.htm
Cannabinoids Induce Apoptosis of Pancreatic Tumor Cells via Endoplasmic Reticulum StressRelated Genes (full - 2006) http://cancerres.aacrjournals.org/cgi/content/full/66/13/6748 Cannabinoid derivatives induce cell death in pancreatic MIA PaCa-2 cells via a receptorindependent mechanism. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16500647 Cannabinoids Halt Pancreatic Cancer, Breast Cancer Growth, Studies Say (news - 2006)
http://www.thehempire.com/index.php/cannabis/news/cannabinoids_halt_pancreatic_cancer_breast_cancer _growth_studies_say
Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects (full 2008) http://gut.bmj.com/content/57/8/1140.full Cannabinoids in pancreatic cancer: Correlation with survival and pain
(full - 2008) (full 2009)

Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism. (full 2011)
http://www.nature.com/cddis/journal/v2/n4/pdf/cddis201136a.pdf
145
CANCER - PITUITARY ADENOMA Normal Human Pituitary Gland and Pituitary Adenomas Express Cannabinoid Receptor Type 1 and Synthesize Endogenous Cannabinoids: First Evidence for a Direct Role of Cannabinoids on Hormone Modulation at the Human Pituitary Level (full - 2001)
http://jcem.endojournals.org/cgi/content/full/86/6/2687?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=marihuana&searchid=1&FIRSTINDEX=1760&resourcetype=HWCIT
CANCER PNET / PRIMITIVE NEUROECTODERMAL TUMOR Distinctive pattern of cannabinoid receptor type II (CB2) expression in adult and pediatric brain tumors. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17239827 Father: Medical marijuana eased pain of my cancer-battling son
(anecdotal 2011)
CANCER - PROSTATE 9-Tetrahydrocannabinol induces apoptosis in human prostate PC-3 cells via a receptorindependent mechanism (abst - 1999)
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T36-3XFTGPRX&_user=10&_coverDate=09%2F24%2F1999&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docancho r=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=e9b3e817c7d39ac7f206 56f24e07dfd1
Suppression of Nerve Growth Factor Trk Receptors and Prolactin Receptors by Endocannabinoids Leads to Inhibition of Human Breast and Prostate Cancer Cell Proliferation (full - 2000)
http://endo.endojournals.org/cgi/content/full/141/1/118?ijkey=9caa0af787d8b2dc94e45918a69b40ea90bc1 776
Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: implication of epidermal growth factor receptor down-regulation and ceramide production. (abst - 2003) http://www.ncbi.nlm.nih.gov/pubmed/12746841?dopt=Abstract Expression of functionally active cannabinoid receptor CB1 in the human prostate gland (abst 2003) http://onlinelibrary.wiley.com/doi/10.1002/pros.10165/abstract 2-Arachidonoylglycerol A Novel Inhibitor of Androgen-Independent Prostate Cancer Cell Invasion (full - 2004)
http://cancerres.aacrjournals.org/cgi/content/full/64/24/8826?ijkey=951f5f9d238bdf059cf30ee2be3a5a31aa f2b094
146
A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells. (full 2005)
Cannabinoid Receptor as a Novel Target for the Treatment of Prostate Cancer (full - 2005) http://cancerres.aacrjournals.org/cgi/reprint/65/5/1635.pdf Cannabinoid Receptor Agonist-induced Apoptosis of Human Prostate Cancer Cells LNCaP Proceeds through Sustained Activation of ERK1/2 Leading to G1 Cell Cycle Arrest (full - 2006) http://www.jbc.org/content/281/51/39480.full Diverse roles of 2-arachidonoylglycerol in invasion of prostate carcinoma cells: Location, hydrolysis and 12-lipoxygenase metabolism (full 2007)
US Patent Application 20070041994 - Compositions and methods for treating prostate disorders ( full 2007) http://www.patentstorm.us/applications/20070041994/fulltext.html Cannabinoid receptors agonist WIN-55,212-2 inhibits angiogenesis, metastasis and tumor growth of androgen-sensitive prostate cancer cell CWR22R{nu}1 xenograft in athymic nude mice (abst - 2007)
Endocannabinoids in endocrine and related tumours

(full - 2008)
Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)Methanandamide and JWH-015: Involvement of CB2 (full - 2009)
http://www.nature.com/bjc/journal/v101/n6/full/6605248a.html
The cannabinoid R+ methanandamide induces IL-6 secretion by prostate cancer PC3 cells. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19908944 Active Chemicals in Cannabis Inhibits Prostate Cancer Cell Growth Cannabis is linked to a 'cancer cure'. (news 2009) (news - 2009) (news - 2009) (news - 2009)
http://www.elements4health.com/active-chemicals-in-cannabis-inhibits-prostate-cancer-cell-growth.html
http://www.thefreelibrary.com/Cannabis+is+linked+to+a+%27cancer+cure%27+HEALTH.-a0206081618
Cannabis chemicals may help fight prostate cancer Chemicals in cannabis found to stop prostate cancer
http://www.reuters.com/article/healthNews/idUSTRE57I02Z20090819
http://www.examiner.com/examiner/x-19678-Cannabis-Revolution-Examiner~y2009m8d19-Chemicals-incannabis-found-to-stop-prostate-cancer
147
Active cannabis chemicals halt prostate cancer cell growth
(news - 2009)
http://www.news-medical.net/news/20090908/Active-cannabis-chemicals-halt-prostate-cancer-cellgrowth.aspx
Cannabis may apparently stop prostate cancer growth
(news - 2009)
http://www.healthjockey.com/2009/08/21/cannabis-may-apparently-stop-prostate-cancer-growth/
Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines. (full 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930808/?tool=pubmed Cannabis chemicals may help fight prostate cancer (news - 2010)
http://www.abbotsfordtimes.com/entertainment/movieguide/Cannabis+chemicals+help+fight+prostate+cancer/1908592/story.html?id=1908592#Comments

(full 2011)
The endocannabinoid system in prostate cancer.

(abst 2011)
Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22110202 The putative cannabinoid receptor GPR55 defines a novel autocrine loop in cancer cell proliferation. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/20838378 Cannabinoid Receptor Type 1 (CB1) Activation Inhibits Small GTPase RhoA Activity and Regulates Motility of Prostate Carcinoma Cells. (abst 2012)
CANCER - RHABDOMYOSARCOMA Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma (full - 2009) http://mct.aacrjournals.org/content/8/7/1838.full
148
CANCER - RISK CANNABIS VS TOBACCO So, you thought it was the tar that caused cancer... (news - no date)

(news - 1994)
Premiere British Medical Journal Pronounces Marijuana Safer Than Alcohol, Tobacco (news - 1998) http://cannabislink.ca/medical/safer.html Why Doesn't Smoking Marijuana Cause Cancer?
http://www.healthcentral.com/drdean/408/14275.html
(news - 1999) (full - 2005)
Cannabis and tobacco smoke are not equally carcinogenic

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1277837
Smoking Marijuana Does Not Cause Lung Cancer

(news - 2005) (news - 2005)
Cannabis Smoke Is Less Likely To Cause Cancer Than Tobacco Smoke

Blunt Smokers Link Dependence Potential To Nicotine

(news - 2006)
Marijuana Smoking Found Non-Carcinogenic Cannabis Smoke and Cancer: Assessing the Risk
(news - 2006) (news - 2008)
Hypothesizing that marijuana smokers are at a significantly lower risk of carcinogenicity relative to tobacco-non-marijuana smokers: evidenced based on statistical reevaluation of current literature. (full - 2008)
http://www.thefreelibrary.com/Hypothesizing+that+marijuana+smokers+are+at+a+significantly+lower...a0196052086
CANCER - SKIN Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors (full - 2003) http://www.jci.org/cgi/content/full/111/1/43?ijkey=MpUgjDbqHybAU
149
Starting Point Of Sun-Induced Skin Cancer Discovered: Molecular 'Hooks' Also Pull Compounds From Marijuana From Bloodstream (news - 2008)
U of Minnesota researcher discovers the starting point of sun-induced skin cancer (news 2008)
http://www.bio-medicine.org/medicine-news-1/U-of-Minnesota-researcher-discovers-the-starting-point-ofsun-induced-skin-cancer-19419-1/
Cannabis Science Provides Physicians Documentation That Confirms Successful Treatment of Skin Cancer (news/ info-mercial 2011)
http://www.businesswire.com/news/home/20110406006516/en/Cannabis-SciencePhysician%E2%80%99s-Documentation-Confirms-Successful-Treatment
CANCER SQUAMOUS CELL CARCINOMA Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors (full 2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC151833/ Marijuana use and Risk of Oral Squamous Cell Carcinoma
(full - 2004)
Peripheral Cannabinoids Attenuate Carcinoma Induced Nociception in Mice (full 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771220/ A Population-Based Case-Control Study of Marijuana Use and Head and Neck Squamous Cell Carcinoma. (abst - 2009)
http://cancerpreventionresearch.aacrjournals.org/cgi/content/abstract/2/8/759
Effects of Cannabinoids on Oral Squamous Cell Carcinoma Proliferation (abst 2009)

http://iadr.confex.com/iadr/2009miami/webprogram/Paper120589.html
Cannabis Oil Shrinks One Of The Worst Cancers (warning: graphic photos)
(news infomercial 2012)
http://cannabiscureuk.wordpress.com/2012/01/11/breaking-news-cannabis-science-inc-cannabis-oilshrinks-one-of-the-worst-cancers/
150
CANCER - TESTICULAR Chemotherapy for Testicular Cancer (anecdotal - no date)

http://www.rxmarihuana.com/shared_comments/testicularchemo.htm
Crossover comparison of the antiemetic efficacy of nabilone and alizapride in patients with nonseminomatous testicular cancer receiving cisplatin therapy (abst- 1986)
CANCER - THYMOMA A comparative study on cannabidiol-induced apoptosis in murine thymocytes and EL-4 thymoma cell (abst- 2008)
http://www.greenmedinfo.com/article/cannabinoids-may-have-therapeutic-role-play-treating-thyoma
CANCER - THYROID Control by the endogenous cannabinoid system of ras oncogene-dependent tumor growth (full - 2001)
http://www.fasebj.org/cgi/reprint/15/14/2745?ijkey=1b6e92836655dd275d36c82a7957423ec2106c6a
Inhibitory effects of cannabinoid CB1 receptor stimulation on tumor growth and metastatic spreading: actions on signals involved in angiogenesis and metastasis1 (full - 2003) http://www.fasebj.org/cgi/reprint/17/12/1771 A new strategy to block tumor growth by inhibiting endocannabinoid inactivation. (full 2006) http://www.fasebj.org/content/early/2004/10/02/fj.04-1754fje.long Endocannabinoids in endocrine and related tumours
(full - 2008)
Cannabinoid 2 receptor induction by IL-12 and its potential as a therapeutic target for the treatment of anaplastic thyroid carcinoma. (abst - 2008)
http://www.unboundmedicine.com/medline/ebm/record/18197164/full_citation/Cannabinoid_2_receptor_in duction_by_IL_12_and_its_potential_as_a_therapeutic_target_for_the_treatment_of_anaplastic_thyroid_ca rcinoma_
A metabolically stable analogue of anandamide, Met-F-AEA, inhibits human thyroid carcinoma cell lines by activation of apoptosis (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19189054/abstract/A_metabolically_stable_analog ue_of_anandamide_Met_F_AEA_inhibits_human_thyroid_carcinoma_cell_lines_by_activation_of_apopto sis_
151
CANCER - VARIOUS/ UNNAMED Unpublished Federal Study Found THC-Treated Rats Lived Longer, Had Less Cancer (news - no date)
http://www.drugsense.org/mcwilliams/www.marijuanamagazine.com/toc/rats.htm
Analgesic effect of delta-9-tetrahydrocannabinol.
(abst - 1975) (abst - 1975)
The analgesic properties of delta-9-tetrahydrocannabinol and codeine.

Delta-9-tetrahydrocannabinol as an antiemetic for patients receiving cancer chemotherapy. A comparison with prochlorperazine and a placebo. (abst - 1979)
Delta-9-tetrahydrocannabinol as an antiemetic in cancer patients receiving high-dose methotrexate A prospective, randomized evaluation (abst - 1979)
Delta-9-tetrahydrocannabinol (THC) as an antiemetic in patients treated with cancer chemotherapy; a double-blind cross-over trial against placebo (abst - 1979)
Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9-tetrahydrocannabinol. (abst - 1979)

Superiority of nabilone over prochlorperazine as an antiemetic in patients receiving cancer chemotherapy. (abst - 1979)
The antiemetic activity of tetrahydrocanabinol versus metoclopramide and thiethylperazine in patients undergoing cancer chemotherapy. (abst - 1980)
A multi-institutional Phase III study of nabilone vs. placebo in chemotherapy-induced nausea and vomiting. (abst - 1982)
Prospective randomized double-blind trial of nabilone versus domperidone in the treatment of cytotoxic-induced emesis (abst - 1986)
152
Efficacy of tetrahydrocannabinol in patients refractory to standard anti-emetic therapy (abst - 1988) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=31 Dronabinol enhancement of appetite in cancer patients. (abst - 1990)
Dronabinol and prochlorperazine in combination for treatment of cancer chemotherapyinduced nausea and vomiting. (abst - 1991)
A phase II study of delta-9-tetrahydrocannabinol for appetite stimulation in cancerassociated anorexia (abst -1994)
NTP Technical Report on the Toxicology and Carcinogenesis Studies of 1-Trans-Delta9Tetrahyrdocannabinol (CAS No. 1972-08-3) in F344/N Rats and B6C3F1 Mice (Gavage Studies) (full - 1996) http://www.druglibrary.org/Schaffer/hemp/Trans-Delta%20Report.pdf Toxicity and Carcinogenicity of {Delta}9-Tetrahydrocannabinol in Fischer Rats and B6C3F1 Mice (abst - 1996)
http://toxsci.oxfordjournals.org/cgi/content/abstract/30/1/109?maxtoshow=&hits=80&RESULTFORMAT= &fulltext=marihuana&searchid=1&FIRSTINDEX=240&resourcetype=HWCIT
Study: THC Not Cancer-Causing
(news - 1997)
http://www.ukcia.org/research/cancer.php
Therapeutic Aspects of Cannabis and Cannabinoids

(full - 2001)
Anti-Tumor Effects (news - 2001)
http://www.ukcia.org/research/AntiTumorEffects.htm
Targeting the endocannabinoid system in cancer therapy: A call for further research (full - 2002) http://www.fuoriluogo.it/medicalcannabis/documenti/bifulco2002.pdf Patent 6410588 Use of cannabinoids as anti-inflammatory agents
(full 2002)
Endocannabinoids in the immune system and cancer.

(abst - 2002)

(full - 2003) (full - 2003)
http://www.fasebj.org/cgi/reprint/02-0795fjev1?ijkey=93a5d281f850b12428c0ce7239c7af67fe8fab6f
153
Established and potential therapeutic applications of cannabinoids in oncology (abst + intro - 2003) http://www.springerlink.com/content/py9cunbm343und5v/ The effects of smoked cannabis in painful peripheral neuropathy
(abst - 2003)

(abst - 2003)
Cannabinoid receptor systems: therapeutic targets for tumour intervention (abst - 2003) http://informahealthcare.com/doi/abs/10.1517/14728222.7.6.749 Cannabis May Help Combat Cancer-causing Herpes Viruses
(news - 2004)
THC in marijuana may block the spread of forms of cancer causing herpes viruses (news - 2004) http://www.news-medical.net/news/2004/09/22/4990.aspx Cancer Killer (news - 2004) http://www.november.org/stayinfo/breaking2/CancerKiller.html (full 2005)
Medicinal Cannabis in Oncology Practice: Still a Bridge Too Far?

http://jco.ascopubs.org/content/23/13/2886.full.pdf+html
Involvement of Cannabinoids in Cellular Proliferation

http://www.bentham.org/mrmc/sample/mrmc5-1/0008N.pdf
(full - 2005)
The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells. (full - 2006)
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WWK-4JP3G9H8&_user=10&_coverDate=04%2F30%2F2006&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sor t=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=3d4033 9063a535f66fd180bef7aac1e9&searchtype=a
Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled clinical trial from the Cannabis-InCachexia-Study-Group. (full - 2006) http://jco.ascopubs.org/content/24/21/3394.long Cannabinoids and cancer: pros and cons of an antitumour strategy
(full - 2006)
Cannabinoids As Cancer Hope
(article - 2006)
154
The synthetic cannabinoid nabilone improves pain and symptom management in cancer patients (abst - 2006)
Different views on the association between cannabinoids and cancer
(abst - 2006)
Cannabinoids Halt Pancreatic Cancer, Breast Cancer Growth, Studies Say (news - 2006)
http://www.thehempire.com/index.php/cannabis/news/cannabinoids_halt_pancreatic_cancer_breast_cancer _growth_studies_say
Marijuana Smoking Found Non-Carcinogenic
(news - 2006)
Inhibition of Cancer Cell Invasion by Cannabinoids via Increased Expression of Tissue Inhibitor of Matrix Metalloproteinases-1 (full - 2007)
A Cannabinoid Anticancer Quinone, HU-331, Is More Potent and Less Cardiotoxic Than Doxorubicin: A Comparative in Vivo Study (full - 2007)
Sativex: Fact Sheet
(full - 2007) (letter - 2007)
http://www.bayer.ca/files/sativex_fs_fd_109461_e%20_GW_.pdf
Sativex: Health Care Professional letter
http://www.bayer.ca/files/sativex_dhcpl_lapds_109461_e%20_GW_-2.pdf
Endocannabinoids as emerging suppressors of angiogenesis and tumor invasion (Review) (abst- link to full PDF 2007) http://www.spandidos-publications.com/or/17/4/813 A cannabinoid agonist differentially attenuates deep tissue hyperalgesia in animal models of cancer and inflammatory muscle pain. (abst 2007)
Antiangiogenic activity of the endocannabinoid anandamide: correlation to its tumorsuppressor efficacy. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17192847 Science: The use of cannabis does not influence the efficacy of two anti-cancer drugs, a clinical study finds (news - 2007)
No Decrease in Pulmonary Function Associated with Long-Term Cannabis Smoking, Study Says (news - 2007) http://www.illinoisnorml.org/content/view/366/27/ Nabilone relieves many advanced Ca symptoms (news - 2007)
http://findarticles.com/p/articles/mi_hb4365/is_9_40/ai_n29428135/?tag=content;col1
155
Cannabinoids May Inhibit Cancer Cell Invasion Marijuana could suppress Tumor Cell Growth
(news - 2007) (news - 2007) (full - 2008)
http://www.healthjockey.com/2007/12/29/marijuana-could-suppress-tumor-cell-growth/
Cannabinoids for Cancer Treatment: Progress and Promise


(full - 2008)
Nabilone for the treatment of paraneoplastic night sweats: a report of four cases (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/18715188 Science: Nabilone effective in the treatment of night sweats of four patients with advanced cancer (news 2008)
Cannabis Smoke and Cancer: Assessing the Risk

(news - 2008)
How Cannabis Compares to other treatments Marijuana May Prevent Cancer, Not Cause It
(news - 2008) (news - 2008)
http://www.entheology.org/edoto/anmviewer.asp?a=293&print=yes
(full - 2009)
TRB3 links ER stress to autophagy in cannabinoid antitumoral action (abst + link to full PDF - 2009) http://www.landesbioscience.com/journals/autophagy/article/9508 Use of cannabinoid receptor agonists in cancer therapy as palliative and curative agents. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19285265 Cannabinoids in the treatment of cancer
(abst - 2009)
156
Use of cannabinoid receptor agonists in cancer therapy as palliative and curative agents (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19285265 Hexahydrocannabinols, novel synthetic cannabinoid derivatives, suppress the tumor growth by inhibiting the VEGF secretion and angiogenesis (abst - 2009)
http://www.fasebj.org/cgi/content/meeting_abstract/23/1_MeetingAbstracts/761.3?maxtoshow=&hits=10& RESULTFORMAT=&fulltext=cannabis&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspe c=relevance&resourcetype=HWCIT
A Population-Based Case-Control Study of Marijuana Use and Head and Neck Squamous Cell Carcinoma. (abst - 2009)
http://cancerpreventionresearch.aacrjournals.org/cgi/content/abstract/2/8/759
Cannabinoid receptor ligands as potential anticancer agents--high hopes for new therapies? (abst - 2009)
Cannabis Compounds have "Palliative" and "Curative" Effects on Cancer

(news - 2009)
Could smoking pot cut risk of head, neck cancer?
(news - 2009)
http://www.health.am/cr/more/could-smoking-pot-cut-risk-of-head-neck-cancer/
NEW USE FOR CANNABINOID-CONTAINING PLANT EXTRACTS Patent application number: 20100249223 (full - 2010)
http://www.faqs.org/patents/app/20100249223
US Patent Application 20100204312 - METHODS AND COMPOSITIONS FOR TREATING CANCER (full - 2010)
Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain. (abst - 2010)
Targeting the Endocannabinoid System for the Treatment of Cancer - A Practical View. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20370711?dopt=Abstract Cannabis-derived substances in cancer therapy--an emerging anti-inflammatory role for the cannabinoids. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20925645 Antitumorigenic Effects of Cannabinoids beyond Apoptosis
http://jpet.aspetjournals.org/content/332/2/336.abstract
(abst - 2010)
Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19914218
157
Vets use hemp seed oil on animals with cancer
(news - 2010)
http://www.examiner.com/x-33448-LA-County-Environmental-News-Examiner~y2010m3d22-Vets-usehemp-seed-oil-on-animals-with-cancer
Cannabis Rx: Cutting Through the Misinformation : Dr. Andrew Weil (news - 2010)
Update on the endocannabinoid system as an anticancer target.

(abst 2011)
Intrathecal Administration of the Cannabinoid 2 Receptor Agonist JWH015 Can Attenuate Cancer Pain and Decrease mRNA Expression of the 2B Subunit of N-Methyld-Aspartic Acid (abst 2011)
http://www.anesthesiaanalgesia.org/content/early/2011/04/25/ANE.0b013e31821d1062.abstract?maxtoshow=&hits=80&RESUL TFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype=HWC IT

http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2011.01327.x/abstract
(abst 2011)
Arachidonoyl ethanolamide (AEA)-induced apoptosis is mediated by J-series prostaglandins and is enhanced by fatty acid amide hydrolase (FAAH) blockade. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21432910/abstract/Arachidonoyl_ethanolamide__ AEA__induced_apoptosis_is_mediated_by_J_series_prostaglandins_and_is_enhanced_by_fatty_acid_ami de_hydrolase__FAAH__blockade_
(news 2011) (news 2011)
Worth Repeating: You Cant Censor Cannabis Cancer Treatment The Illegal Herb that Fights Cancer (news - 2011)
http://www.tokeofthetown.com/2011/03/worth_repeating_you_cant_censor_cannabis_cancer_tr.php#more
http://www.cannabisculture.com/v2/node/27122
Another Study Confirms Anti-Cancer Effects of THC and CBD
(news 2011)
http://www.examiner.com/medical-marijuana-in-philadelphia/another-study-confirms-anti-cancer-effectsof-thc-and-cbd-1
Why doesnt marijuana cause cancer?
(news 2011)
http://www.examiner.com/drug-policy-in-reno/why-doesn-t-marijuana-cause-cancer
158
Arachidonoyl ethanolamide (AEA)-induced apoptosis is mediated by J-series prostaglandins and is enhanced by fatty acid amide hydrolase (FAAH) blockade. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/21432910
CANNABICHROMENE/ CBC - phytocannabinoid, unknown receptor Constituents of Cannabis sativa L. VIII: Possible biological application of a new method to separate cannabidiol and cannabichromene. (abst - 1975)
Biological activity of cannabichromene, its homologs and isomers.

(abst - 1981)
Process for preparing cannabichromene
(full - 1982)
http://www.patentstorm.us/patents/4315862/description.html
Neurobehavioral actions of cannabichromene and interactions with delta 9tetrahydrocannabinol. (abst 1983) http://www.ncbi.nlm.nih.gov/pubmed/6301931 Allergenic properties of naturally occurring cannabinoids.
(abst - 1983)
Neurobehavioral actions of cannabichromene and interactions with delta 9tetrahydrocannabinol. (abst - 1983) http://www.ncbi.nlm.nih.gov/pubmed/6301931 Intraocular pressure, ocular toxicity and neurotoxicity after administration of delta 9tetrahydrocannabinol or cannabichromene. (abst 1984)
Antiinflammatory and antimicrobial compounds and compositions United States Patent 4837228 (full - 1989)
http://www.freepatentsonline.com/4837228.html
In vitro metabolism of cannabichromene in seven common laboratory animals. (abst 1990) http://www.ncbi.nlm.nih.gov/pubmed/1981514 Antibacterial cannabinoids from Cannabis sativa: a structure-activity study. (full - 2008)
Evaluation of Prevalent Phytocannabinoids in the Acetic Acid Model of Visceral Nociception (full 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765124/?tool=pubmed
159

(full 2009)
Antidepressant-like effect of Delta(9)-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L. (full - 2010)
Disposition of Cannabichromene, Cannabidiol, and 9-Tetrahydrocannabinol and its Metabolites in Mouse Brain following Marijuana Inhalation Determined by HighPerformance Liquid Chromatography-Tandem Mass Spectrometry (abst - 2010)
Pharmacological evaluation of the natural constituent of Cannabis sativa, cannabichromene and its modulation by 9-tetrahydrocannabinol (abst - 2010)

(full 2011)
Cannabis Science Reports: National Cancer Institute Updates Confirm Successful Cancer Treatments with Medical Cannabis. (news - 2011)
http://www.thefreelibrary.com/Cannabis+Science+Reports%3a+National+Cancer+Institute+Updates+Conf irm...-a0252875363
The intersection between cannabis and cancer in the United States.

(abst 2011)
Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/20942863/abstract/Non_psychoactive_cannabinoid s_modulate_the_descending_pathway_of_antinociception_in_anaesthetized_rats_through_several_mechani sms_of_action_
(abst 2011)
CANNABIDIOL/ CBD GPR 55 agonist, antagonist of CB1 and CB2 ACCESSING 0.5 to 2.0 GRAMS CBD FRACTIONATING THE PHYTOCANNABINOIDS BY THEIR VAPORIZATION POINTS
http://forum.grasscity.com/medical-marijuana/610429-need-cbd.html
(article - no date )
160
Effects of cannabidiol derivatives on intestinal motility
(abst - no date)
http://www.docstoc.com/docs/26071658/Effects-of-cannabidiol-derivatives-on-intestinal-motility-
STUDIES ON THE PHARMACOLOGY AND ACUTE TOXICITY OF COMPOUNDS WITH MARIHUANA ACTIVITY (abst - 1946)
Some actions of delta-1 tetrahydrocannabinol and cannabidiol at cholinergic junctions. (full 1971) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1703324/pdf/brjpharm00552-0217.pdf A metabolic interaction in vivo between cannabidiol and 1-tetrahydrocannabinol (full - 1972) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1666148/?tool=pubmed Interactions in man of delta-9-tetrahydrocannabinol. II. Cannabinol and cannabidiol. (abst 1975) http://www.ncbi.nlm.nih.gov/pubmed/1097148 Differential effect of cannabinol and cannabidiol on THC-induced responses during abstinence in morphine-dependent rats. (abst - 1975)
Constituents of Cannabis sativa L. VIII: Possible biological application of a new method to separate cannabidiol and cannabichromene. (abst - 1975)
The influence of delta9-tetrahydrocannabinol, cannabinol and cannabidiol on tissue oxygen consumption. (abst 1975) http://www.ncbi.nlm.nih.gov/pubmed/1197914 Absence of interaction between delta9-tetrahydrocannabinol (delta-THC) and cannabidiol (CBD) in aggression, muscle control and body temperature experiments in mice. (abst 1975) http://www.ncbi.nlm.nih.gov/pubmed/1171491 Anticonvulsant activity of four oxygenated cannabidiol derivatives.
(abst 1975) (abst - 1976)
Cannabidiol--antiepileptic drug comparisons and interactions in experimentally induced seizures in rats. (abst - 1977)
http://jpet.aspetjournals.org/content/201/1/26.abstract?ijkey=8457ace5313942358e64d156c12d04bd3c7d5f 21&keytype2=tf_ipsecsha
In vivo effects of cannabinoids on macromolecular biosynthesis in Lewis lung carcinomas. (abst - 1977) http://www.ncbi.nlm.nih.gov/pubmed/616322
161
Interaction of cannabidiol and alcohol in humans.

(abst 1979)
CHRONIC ADMINISTRATION OF CANNABIDIOL TO HEALTHY VOLUNTEERS AND EPILEPTIC PATIENTS (full - 1980) http://web.acsalaska.net/~warmgun/es201.html Sedative activity of cannabis in relation to its delta'-trans-tetrahydrocannabinol and cannabidiol content. (full - 1981)
Antiepileptic potential of cannabidiol analogs.

(abst - 1981) (abst - 1981)
The cannabinoids as potential antiepileptics.

Effects of cannabidiol on behavioral seizures caused by convulsant drugs or current in mice. (abst - 1982) http://www.ncbi.nlm.nih.gov/pubmed/6129147 Anticonvulsant effects of the (-) and (+)isomers of cannabidiol and their dimethylheptyl homologs. (abst - 1982)
Allergenic properties of naturally occurring cannabinoids.

(abst - 1983)
Ocular Hypotension, Ocular Toxicity, and Neurotoxicity in Response to Marihuana Extract and Cannabidiol. (abst - 1984)
Stimulation of Sphingomyelin Hydrolysis by Cannabidiol in Fibroblasts from a Niemannpick Patient. (abst - 1984)
http://medical-journals.healia.com/doc/6732800/Stimulation-of-sphingomyelin-hydrolysis-by-cannabidiolin-fibroblasts-from-a-Niemann-Pick-patient
Treatment of Meige's syndrome with cannabidiol.
(abst - 1984)
The quasi-morphine withdrawal syndrome: effect of cannabinol, cannabidiol and tetrahydrocannabinol. (abst - 1985)
Beneficial and adverse effects of cannabidiol in a Parkinson patient with sinemet-induced dystonic dyskinesia. (abst - 1985)
162
Open label evaluation of cannabidiol in dystonic movement disorders.

(full - 1986)
EFFECTS OF CANNABIDIOL IN HUNTINGTON'S DISEASE

http://www.druglibrary.org/schaffer/hemp/medical/hunting1.htm
(abst - 1986)
Cannabidiol in dystonic movement disorders.
(abst - 1986)
The inhibitory effects of cannabinoids, the active constituents of Cannabis sativa L. on human and rabbit platelet aggregation. (abst - 1989)
Antianxiety effect of cannabidiol in the elevated plus-maze.

(abst 1990)
Mammary excretion of cannabidiol in rabbits after intravenous administration. (abst - 1994)

Cannabidiol and ()9-tetrahydrocannabinol are neuroprotective antioxidants (full - 1998) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=20965&tool=pmcentrez Marijuana chemical tapped to fight strokes ? (news - 1998) (news 1998)
http://findarticles.com/p/articles/mi_m1200/is_n2_v154/ai_20973037/?tag=content;col1
Cannabinoid Antioxidant Protects Brain Cells -- Without the High

Cannabinoids might reduce spasticity in multiple sclerosis

(full - 2000)
The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis (full - 2000)
http://www.pnas.org/cgi/content/full/97/17/9561
Advantages of polypharmaceutical herbal cannabis compared to single ingredient, synthetic tetrahydrocannabinol (full - 2000)
http://www.cannabis-science.com/papers/cannabis%20terpenes.pdf
Variations of D9-THC content in single plants of hemp varieties

http://www.ukcia.org/research/VariationOfTHCContent.pdf
(full - 2000)
Neuroprotective Antioxidants from Marijuana
(abst 2000)
163
Different effects of nabilone and cannabidiol on binocular depth inversion in Man. (abst 2000) http://www.ncbi.nlm.nih.gov/pubmed/10837858 Synthesis of a primary metabolite of cannabidiol.
(abst 2000)
Cannabinoids in clinical practice.
(abst - 2000) (news - 2000)
Marijuana Extract Helps Arthritis Pain
Cannabinoid effects on anxiety-related behaviours and hypothalamic neurotransmitters. (abst - 2001) http://www.ncbi.nlm.nih.gov/pubmed/11566149 Composition of the essential oils and extracts of two populations of Cannabis sativa L. ssp. spontanea from Austria (full - 2003)
http://findarticles.com/p/articles/mi_qa4091/is_/ai_n9299539
Vasodilator actions of abnormal-cannabidiol in rat isolated small mesenteric artery (full - 2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573773/?tool=pmcentrez Cannabis and the brain. (full - 2003) http://brain.oxfordjournals.org/cgi/content/full/126/6/1252
Post-ischemic Treatment with Cannabidiol Prevents Electroencephalographic Flattening, Hyperlocomotion and Neuronal Injury in Gerbils. (abst 2003)
http://www.sciencedirect.com/science/article/pii/S030439400300569X
Neuroprotective Effect of()9-Tetrahydrocannabinol and Cannabidiol in N-Methyl-dAspartate-Induced Retinal Neurotoxicity - Involvement of Peroxynitrite (full - 2003)

(abst - 2003)
Gamma-irradiation enhances apoptosis induced by cannabidiol, a non-psychotropic cannabinoid, in cultured HL-60 myeloblastic leukemia cells. (abst - 2003)
Cannabidiol-transdermal delivery and anti-inflammatory effect in a murine model. (abst - 2003) http://www.ncbi.nlm.nih.gov/pubmed/14644587 Anti-tumor effects of cannabidiol, a non-psychotropic cannabinoid, on human glioma cell lines (abst - 2003) http://www.hempworld.com/HempPharm/articles/milanstudy.html Initial experiences with medicinal extracts of cannabis for chronic pain: Results from 34 N of 1 studies (full - 2004) http://www.ukcia.org/research/InitialExperiencesChronicPain.pdf
164
Cannabidiol prevents infarction via the non-CB1 cannabinoid receptor mechanism. (abst 2004) http://www.ncbi.nlm.nih.gov/pubmed/15640760 Cannabidiol Preserves Retinal Neurons and Reduces Vascular Permeability in Experimental Diabetes (abst - 2004)
http://abstracts.iovs.org/cgi/content/abstract/45/5/860?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabinoid&searchid=1&FIRSTINDEX=1760&resourcetype=HWCIT
Effect of Delta-9-tetrahydrocannabinol and cannabidiol on nocturnal sleep and earlymorning behavior in young adults. (abst - 2004)
Comparison of Cannabidiol, Antioxidants, and Diuretics in Reversing Binge EthanolInduced Neurotoxicity (full - 2005) http://jpet.aspetjournals.org/content/314/2/780.full Cannabidiol inhibits human glioma cell migration through a cannabinoid receptorindependent mechanism (full - 2005)
Cannabidiol Prevents Cerebral Infarction Via a Serotonergic 5-Hydroxytryptamine1A ReceptorDependent Mechanism (full - 2005)
http://stroke.ahajournals.org/cgi/content/full/36/5/1071
Cannabidiol lowers incidence of diabetes in non-obese diabetic mice

(full - 2005)
Cannabinol delays symptom onset in SOD1 (G93A) transgenic mice without affecting survival. (abst - 2005)
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=1618356 0
Peripheral, but not central effects of cannabidiol derivatives: mediation by CB(1) and unidentified receptors. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/15910887 Cannabidiol as an antipsychotic. A double-blind, controlled clinical trial on cannabidiol vs. amisulpride in acute schizophrenia. (abst - 2005)
Treatment with CBD in oily solution of drug-resistant paediatric epilepsies. (abst - 2005)
http://www.cannabismed.org/studies/ww_en_db_study_show.php?s_id=173&&search_pattern=EPILEPSY
165
Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson's disease. (abst - 2005)
Chemicals in Cannabis may help mentally ill
(news - 2005)
Neuroprotective and Blood-Retinal Barrier-Preserving Effects of Cannabidiol in Experimental Diabetes (full - 2006)
Role of the Cannabinoid System in Pain Control and Therapeutic Implications for the Management of Acute and Chronic Pain Episodes (full - 2006)
A tale of two cannabinoids: The therapeutic rationale for combining tetrahydrocannabinol and cannabidiol. (full - 2006)
http://mcforadhd.free.fr/Russo_Tale_of_Two_Cannabinoids_Med_Hypoth_2006.pdf
Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug
(full - 2006)
http://www.scielo.br/scielo.php?pid=S0100-879X2006000400001&script=sci_arttext#Text
Cannabidiol-Induced Apoptosis in Human Leukemia Cells: A Novel Role of Cannabidiol in the Regulation of p22phox and Nox4 Expression (full - 2006)
The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells. (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16458258 Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats.
(abst - 2006)
Anxiolytic-like effect of cannabidiol in the rat Vogel conflict test.

(abst 2006)
Differential effects of cannabis extracts and pure plant cannabinoids on hippocampal neurones and glia. (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16997463?dopt=Abstract The non-psychoactive cannabidiol triggers caspase activation and oxidative stress in human glioma cells. (abst - 2006)
http://www.ihop-net.org/UniPub/iHOP/pm/12214911.html?pmid=16909207
The marijuana component cannabidiol inhibits beta-amyloid-induced tau protein hyperphosphorylation through Wnt/beta-catenin pathway rescue in PC12 cells. (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16389547
166
Cannabidiol inhibits inducible nitric oxide synthase protein expression and nitric oxide production in beta-amyloid stimulated PC12 neurons through p38 MAP kinase and NFkappaB involvement. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16490313 Cannabidiol inhibits tumour growth in leukaemia and breast cancer (news - 2006)
Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells. (full - 2007) http://mct.aacrjournals.org/content/6/11/2921.long The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: 9tetrahydrocannabinol, cannabidiol and 9-tetrahydrocannabivarin (full - 2007)
Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption (full - 2007)
Cannabidiol in vivo blunts -amyloid induced neuroinflammation by suppressing IL-1 and iNOS expression (full - 2007)
Cannabidiol, a nonpsychoactive Cannabis constituent, protects against myocardial ischemic reperfusion injury (full - 2007)
http://ajpheart.physiology.org/cgi/content/full/293/6/H3602
Delayed treatment with cannabidiol has a cerebroprotective action via a cannabinoid receptor-independent myeloperoxidase-inhibiting mechanism. (full - 2007)
Cannabidiol, unlike synthetic cannabinoids, triggers activation of RBL-2H3 mast cells (full 2007) http://www.jleukbio.org/content/early/2007/03/05/jlb.1206738.full.pdf+html The multidrug transporter ABCG2 (BCRP) is inhibited by plant-derived cannabinoids. (full 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190019/?tool=pubmed US Patent Application 20070099987 - Treating or preventing diabetes with cannabidiol (full 2007) http://www.patentstorm.us/applications/20070099987/fulltext.html Repeated Treatment with Cannabidiol but Not Delta9-tetrahydrocannabinol Has a Neuroprotective Effect Without the Development of Tolerance (abst - 2007)
167
Interactions of cannabidiol with endocannabinoid signalling in hippocampal tissue. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17419758 Cannabidiol--recent advances. Who's Afraid of Cannabidiol? (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17712814 (news - 2007)
http://www.counterpunch.org/gardner07142007.html
Cannabidiol May be Effective in Preventing Bovine Spongiforme Enzephalopathy (Mad Cow Disease) (news - 2007) http://www.letfreedomgrow.com/articles/fr070916.htm Marijuana Compound Shows Promise In Fighting Breast Cancer
(news - 2007) (news - 2007)
Cannabis may stop Breast Cancer from spreading in the Body Cannabis compound cannabidiol CBD 'halts cancer
http://www.healthjockey.com/2007/11/21/cannabis-may-stop-breast-cancer-from-spreading-in-the-body/
(news - 2007) (news - 2007)
Cannabis compound stops spread of breast cancer: researchers

http://www.cbc.ca/health/story/2007/11/19/cannabis-cancer.html
Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of 9-tetrahydrocannabinol (full - 2008)
US Patent Application 20080262099 - Inhibition of Tumour Cell Migration (full 2008) http://www.patentstorm.us/applications/20080262099/fulltext.html Mediation of Cannabidiol anti-inflammation in the Retina by Equilibrative Nucleoside Transporter and A2A Adenosine Receptor (full - 2008)
Antibacterial cannabinoids from Cannabis sativa: a structure-activity study. (full - 2008)

Cannabidiol, extracted from Cannabis sativa, selectively inhibits inflammatory hypermotility in mice (full - 2008)
Neuroprotective effects of cannabidiol in endotoxin-induced uveitis: critical role of p38 MAPK activation. (full - 2008)
Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action. (full - 2008) http://www.finola.com/CBDreview2008.pdf
168
Effects of cannabidiol on schizophrenia-like symptoms in people who use cannabis (full - 2008)
http://bjp.rcpsych.org/cgi/content/full/192/4/306?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=ca nnabinoid&searchid=1&FIRSTINDEX=1200&resourcetype=HWCIT
The role of the endocannabinoid system in Alzheimer's disease: facts and hypotheses. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18781980 A comparative study on cannabidiol-induced apoptosis in murine thymocytes and EL-4 thymoma cell (abst - 2008)
http://www.greenmedinfo.com/article/cannabinoids-may-have-therapeutic-role-play-treating-thyoma
5-Lipoxygenase and anandamide hydrolase (FAAH) mediate the antitumor activity of cannabidiol, a non-psychoactive cannabinoid. (abst 2008)
The nonpsychoactive cannabis constituent cannabidiol is a wake-inducing agent. (abst - 2008)

http://www.unboundmedicine.com/medline/ebm/record/19045957/abstract/The_nonpsychoactive_cannabis _constituent_cannabidiol_is_a_wake_inducing_agent_
Cannabidiol in medicine: a review of its therapeutic potential in CNS disorders. (abst - 2008)
Inhibition of Breast Cancer Aggressiveness by Cannabidiol

http://cbcrp.org.127.seekdotnet.com/research/PageGrant.asp?grant_id=4903
(abst - 2008)
Can cannabis offer hope for Alzheimer's?
(news - 2008)
http://findarticles.com/p/articles/mi_8002/is_2008_March_11/ai_n38819766/?tag=content;col1
Therapeutic time window of cannabidiol treatment on delayed ischemic damage via highmobility group box1-inhibiting mechanism. (full 2009)
Cannabinoids 9-Tetrahydrocannabinol and Cannabidiol Differentially Inhibit the Lipopolysaccharide-activated NF-B and Interferon-/STAT Proinflammatory Pathways in BV-2 Microglial Cells (full 2009)
Non-psychotropic plant cannabinoids:new therapeutic opportunities from an ancient herb (full - 2009 )
http://cannabisinternational.org/info/Non-Psychoactive-Cannabinoids.pdf

(full - 2009)
169
Evaluation of Prevalent Phytocannabinoids in the Acetic Acid Model of Visceral Nociception (full 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765124/?tool=pubmed The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo (full 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737440/?tool=pubmed Cannabinoids as novel anti-inflammatory drugs. (full - 2009)
Cannabidiol, a Nonpsychotropic Component of Cannabis, Inhibits Cue-Induced Heroin Seeking and Normalizes Discrete Mesolimbic Neuronal Disturbances (full - 2009)
Cannabidiol As a Putative Novel Therapy for Diabetic Retinopathy: A Postulated Mechanism of Action as an Entry Point for Biomarker-Guided Clinical Development. (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955420/?tool=pubmed Cannabidiol: a promising drug for neurodegenerative disorders?
(full - 2009)
Cannabidiol Attenuates Cisplatin-Induced Nephrotoxicity by Decreasing Oxidative/Nitrosative Stress, Inflammation, and Cell Death (full 2009)
Cannabidiol-induced lymphopenia does not involve NKT and NK cells. (full 2009) http://www.jpp.krakow.pl/journal/archive/10_09_s3/pdf/99_10_09_s3_article.pdf Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania (abst 2009) http://jop.sagepub.com/content/25/2/274.abstract Cannabidiol Attenuates Myocardial Dysfunction, Fibrosis, Inflammation, Cell Death and Interrelated Signaling Pathways Associated With Diabetic Cardiomyopathy (abst - 2009)
http://circ.ahajournals.org/cgi/content/meeting_abstract/120/18_MeetingAbstracts/S868?maxtoshow=&hits =80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1680&resourcetype=HWC IT
Cannabidiol decreases bone resorption by inhibiting RANK/RANKL expression and proinflammatory cytokines during experimental periodontitis in rats. (abst - 2009)
Cannabidiol-2',6'-Dimethyl Ether, a Cannabidiol Derivative, Is a Highly Potent and Selective 15-Lipoxygenase Inhibitor. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19406952/abstract/
170
Time-dependent vascular actions of cannabidiol in the rat aorta.

(abst 2009)
Beneficial effects of a Cannabis sativa extract treatment on diabetes-induced neuropathy and oxidative stress. (abst - 2009)
Cannabidiol targets mitochondria to regulate intracellular Ca2+ levels.
(abst 2009)
http://www.unboundmedicine.com/medline/ebm/record/19228959/abstract/Cannabidiol_targets_mitochond ria_to_regulate_intracellular_Ca2+_levels_
Cannabidiol, a safe and non-psychotropic ingredient of the marijuana plant Cannabis sativa, is protective in a murine model of colitis. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19690824/abstract/Cannabidiol_a_safe_and_non_p sychotropic_ingredient_of_the_marijuana_plant_Cannabis_sativa_is_protective_in_a_murine_model_of_c olitis_
Cannabidiol ameliorates cognitive and motor impairments in mice with bile duct ligation. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19596476/abstract/Cannabidiol_ameliorates_cogni tive_and_motor_impairments_in_mice_with_bile_duct_ligation_
Cannabidiol for the treatment of psychosis in Parkinsons disease
(abst - 2009)
http://jop.sagepub.com/cgi/content/abstract/23/8/979?maxtoshow=&hits=80&RESULTFORMAT=&fulltex t=cannabinoid&searchid=1&FIRSTINDEX=1920&resourcetype=HWCIT
Cannabidiol reverses the reduction in social interaction produced by low dose Delta(9)tetrahydrocannabinol in rats. (abst 2009)
Cannabis compound can help cells
(news 2009)
Cannabis plant extracts could potentially form the basic ingredients for a market-leading diabetes drug (news 2009)
http://www.thefreelibrary.com/Cannabis+plant+extracts+could+potentially+form+the+basic+ingredients...a0202701009
Marijuana Chemicals Ease MS Symptoms, Review Confirms

http://www.drugfree.org/uncategorized/marijuana-chemicals-ease-ms
(news - 2009)
171
Cannabis by product helps reduce effects of Parkinson disease medication (news - 2009) http://en.mercopress.com/2009/12/30/cannabis-by-product-helps-reduce-effects-ofparkinson-disease-medication/
Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors (full 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823358/?tool=pubmed Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type I diabetic peripheral neuropathic pain (full - 2010)
Therapeutical use of the cannabinoids in psychiatry

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S151644462010000500009&lng=en&nrm=iso&tlng=en
(full 2010)
Cannabidiol protects retinal neurons by preserving glutamine synthetase activity in diabetes. (full - 2010)
Therapeutic Potential of Non-Psychotropic Cannabidiol in Ischemic Stroke (full 2010)

Cannabidiol Displays Antiepileptiform and Antiseizure Properties In Vitro and In Vivo (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819831/?tool=pmcentrez Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion. (full 2010)
Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis. (full - 2010)
http://www.springerlink.com/content/b81620q7l48h2n51/fulltext.html
Cannabidiol Attenuates Cardiac Dysfunction, Oxidative Stress, Fibrosis, and Inflammatory and Cell Death Signaling Pathways in Diabetic Cardiomyopathy (full - 2010) http://www.natap.org/2010/newsUpdates/marijuana.pdf Antidepressant-like effect of Delta(9)-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L. (full - 2010)
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Cannabidiol ameliorates cognitive and motor impairments in bile-duct ligated mice via 5HT1A receptor activation. (full 2010)
Diabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/21537423/abstract/Diabetic_retinopathy:_Role_of_ inflammation_and_potential_therapies_for_anti_inflammation_
Intra-dorsal periaqueductal gray administration of cannabidiol blocks panic-like response by activating 5-HT1A receptors. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20457188/abstract/Intra_dorsal_periaqueductal_gr ay_administration_of_cannabidiol_blocks_panic_like_response_by_activating_5_HT1A_receptors_
Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20884951 Decrease of plasminogen activator inhibitor-1 may contribute to the anti-invasive action of cannabidiol on human lung cancer cells. (abst - 2010)
Regulation of nausea and vomiting by cannabinoids
(abst - 2010)
http://onlinelibrary.wiley.com/doi/10.1111/j.14765381.2010.01176.x/abstract;jsessionid=56CED9CE51B025C161AA2E821BEC94ED.d01t01
Cannabidiol bioavailability after nasal and transdermal application: effect of permeation enhancers. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20545522 Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20884951 Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19914218 Cannabidiol Enhances the Inhibitory Effects of 9-Tetrahydrocannabinol on Human Glioblastoma Cell Proliferation and Survival (abst - 2010)
http://mct.aacrjournals.org/content/9/1/180.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fulltext =cannabis&searchid=1&FIRSTINDEX=240&sortspec=date&resourcetype=HWCIT
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Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb. (abst - 2010)
Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania. (abst - 2010)
http://www.unboundmedicine.com/medline/ebm/record/19939866/full_citation/Effects_of_cannabidiol_on _amphetamine_induced_oxidative_stress_generation_in_an_animal_model_of_mania_
Opposite Effects of -9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology (abst - 2010)
Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20695034 Cannabidiol attenuates delayed-type hypersensitivity reactions via suppressing T-cell and macrophage reactivity. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/21042286 Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19896326 Disposition of Cannabichromene, Cannabidiol, and 9-Tetrahydrocannabinol and its Metabolites in Mouse Brain following Marijuana Inhalation Determined by HighPerformance Liquid Chromatography-Tandem Mass Spectrometry (abst - 2010)
Treatment with cannabidiol reverses oxidative stress parameters, cognitive impairment and mortality in rats submitted to sepsis by cecal ligation and puncture. (abst - 2010)
Anticonvulsant effects of GWP42006 in vitro and in vivo in rat
(abst - 2010)
The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxicischemic brain damage in mice is mediated by CB(2) and adenosine receptors. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/19900555/abstract/The_neuroprotective_effect_of_ cannabidiol_in_an_in_vitro_model_of_newborn_hypoxic_ischemic_brain_damage_in_mice_is_mediated_ by_CB_2__and_adenosine_receptors_
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Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report (abst - 2010) http://jop.sagepub.com/content/25/1/121 Non-psychoactive cannabis to be unveiled at Annual National Clinical Conference on Cannabis Therapeutics (news - 2010)
http://www.news-medical.net/news/20100409/Non-psychoactive-cannabis-to-be-unveiled-at-AnnualNational-Clinical-Conference-on-Cannabis-Therapeutics.aspx
Prescription Marijuana Without "Intoxicating" Effect in Research Stage
(news - 2010)
http://www.nbclosangeles.com/news/health/Scientists-Aim-to-Make-Marijuana-Perscription-Drug108736999.html
Key ingredient staves off marijuana memory loss
(news - 2010)
http://www.nature.com/news/2010/101001/full/news.2010.508.html?s=news_rss
Medical Marijuana; The active ingredient in marijuana cuts tumor growth in common lung cancer in half and significantly reduces the ability of the cancer to spread, say researchers at Harvard University. (news 2010)
http://www.thefreelibrary.com/Medical+Marijuana%3b+The+active+ingredient+in+marijuana+cuts+tumor ...-a0243683610
Pot Compound Mitigates Diabetic Cardiomyopathy

(news - 2010) (news - 2010)
Cannabinoids inhibit and may prevent neuropathic pain in diabetes. Lab Notes: Pot Has Benefits for Diabetic Hearts
http://www.medpagetoday.com/LabNotes/LabNotes/23853
http://medigardens.blogspot.com/2010/04/march-2010-cannabinoids-inhibit-and-may.html
(news - 2010)
Key ingredient dilutes marijuana's effect on memory.
(news 2010)
http://www.thefreelibrary.com/Key+ingredient+dilutes+marijuana%27s+effect+on+memory.-a0238532965
The potential for clinical use of cannabinoids in treatment of cardiovascular diseases. (full 2011) http://onlinelibrary.wiley.com/doi/10.1111/j.1755-5922.2010.00233.x/pdf Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion (full 2011)
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Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa (full 2011) http://www.jstage.jst.go.jp/article/bpb/34/5/774/_pdf Role of Myeloid-Derived Suppressor Cells in Amelioration of Experimental Autoimmune Hepatitis Following Activation of TRPV1 Receptors by Cannabidiol (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069975/?tool=pmcentrez Cannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis. (full 2011)
Cannabidiol, a Major Phytocannabinoid, as a Potent Atypical Inhibitor for Cytochrome P450 2D6. (full 2011)
http://dmd.aspetjournals.org/content/early/2011/08/05/dmd.111.041384.long
Brief Report: Cannabidiol Prevents the Development of Cold and Mechanical Allodynia in Paclitaxel-Treated Female C57Bl6 Mice. (full 2011)
http://www.anesthesia-analgesia.org/content/113/4/947.long
Cannabidiol Reduces Intestinal Inflammation through the Control of Neuroimmune Axis (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232190/?tool=pubmed Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21704641/abstract/Identification_of_cytochrome_ P450_enzymes_responsible_for_metabolism_of_cannabidiol_by_human_liver_microsomes_
Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent.
(abst - 2011)
http://www.unboundmedicine.com/medline/ebm/record/22129319/abstract/Safety_and_Side_Effects_of_C annabidiol_a_Cannabis_sativa_Constituent_
Cannabidiol as an anti-arrhythmic, the role of the CB1 receptors.
(abst 2011)
Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21144973/abstract/Cannabidiol_attenuates_cardiac _dysfunction_oxidative_stress_fibrosis_and_inflammatory_and_cell_death_signaling_pathways_in_diabeti c_cardiomyopathy_
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The Non-Psychoactive Plant Cannabinoid, Cannabidiol Affects Cholesterol MetabolismRelated Genes in Microglial Cells. (abst 2011)
Cannabidiol decreases body weight gain in rats: Involvement of CB2 receptors. (abst - 2011) http://marijuana.researchtoday.net/archive/8/1/3517.htm Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice. (abst 2011)
Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress. (abst 2011)
Modulation of Auditory and Visual Processing by Delta-9-Tetrahydrocannabinol and Cannabidiol: an fMRI Study. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21412224 CANNABIDIOL INHIBITS PATHOGENIC T-CELLS, DECREASES SPINAL MICROGLIAL ACTIVATION AND AMELIORATES MULTIPLE SCLEROSIS-LIKE DISEASE IN C57BL/6 MICE. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21449980 Anti-Aversive Effects of Cannabidiol on Innate Fear-Induced Behaviors Evoked by an Ethological Model of Panic Attacks Based on a Prey vs the Wild Snake Epicrates cenchria crassus Confrontation Paradigm. (abst - 2011)
Memory-rescuing effects of cannabidiol in an animal model of cognitive impairment relevant to neurodegenerative disorders. (abst 2011)
Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21243485 Cannabidiol, a Non-Psychotropic Component of Cannabis, Attenuates Vomiting and Nausea-like Behaviour via Indirect Agonism of 5-HT(1A) Somatodendritic: Autoreceptors in the Dorsal Raphe Nucleus. (abst 2011)
A novel CB receptor GPR55 and its ligands are involved in regulation of gut movement in rodents. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21726355 Cannabidiol inhibits the hyperphagia induced by cannabinoid-1 or serotonin-1A receptor agonists. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21238476
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Cannabidiol potentiates (9)-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21667074 Inhibitory Effect of Standardized Cannabis sativa Extract and Its Ingredient Cannabidiol on Rat and Human Bladder Contractility. (abst 2011)
Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-nave social phobia patients. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21307846 Effects on sleep and dopamine levels of microdialysis perfusion of cannabidiol into the lateral hypothalamus of rats. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21262236 Cannabidiol induces programmed cell death in breast cancer cells by coordinating the crosstalk between apoptosis and autophagy. (abst 2011)
Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22198381 Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis. (abst 2011)
Cannabidiol, a Non-Psychotropic Component of Cannabis, Attenuates Vomiting and Nausea-like Behaviour via Indirect Agonism of 5-HT(1A) Somatodendritic: Autoreceptors in the Dorsal Raphe Nucleus. (abst 2011)
Regulation of nausea and vomiting by cannabinoids.
(abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21175589/abstract/Regulation_of_nausea_and_vo miting_by_cannabinoids_
The effects of cannabidiolic acid and cannabidiol on contractility of the gastrointestinal tract of Suncus murinus. (abst 2011)
Cannabidiol Dampens Streptozotocin-Induced Retinal Inflammation by Targeting of Microglial Activation (abst - 2011)
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Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), (9)-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessivecompulsive behaviour. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21796370 Cannabis with high cannabidiol content is associated with fewer psychotic experiences. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21592732 A novel CB receptor GPR55 and its ligands are involved in regulation of gut movement in rodents. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21726355 Sub-chronic impact of cannabinoids in street cannabis on cognition, psychotic-like symptoms and psychological well-being. (abst 2011)
Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report. (abst 2011)
Endocannabinoid system and psychiatry: in search of a neurobiological basis for detrimental and potential therapeutic effects. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/22007164/abstract/Endocannabinoid_system_and_ psychiatry:_in_search_of_a_neurobiological_basis_for_detrimental_and_potential_therapeutic_effects_
The endocannabinoid system in the regulation of emotions throughout lifespan: a discussion on therapeutic perspectives. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21693551/abstract/The_endocannabinoid_system_i n_the_regulation_of_emotions_throughout_lifespan:_a_discussion_on_therapeutic_perspectives_
Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and cell death (abst 2011)
Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21362471 Therapeutic potential of cannabidiol against ischemia/reperfusion liver injury in rats. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21930120 Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21238581 Cannabidiol reduces brain damage and improves functional recovery after acute hypoxiaischemia in newborn pigs. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21654550
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Cannabidiol-treated Rats Exhibited Higher Motor Score After Cryogenic Spinal Cord Injury. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21915768 Prospects for cannabinoid therapies in basal ganglia disorders.
(abst 2011) (abst 2011)
Phytocannabinoids as novel therapeutic agents in CNS disorders

THC and CBD oromucosal spray (Sativex) in the management of spasticity associated with multiple sclerosis. (abst - 2011)
http://www.unboundmedicine.com/medline/ebm/record/21456949/abstract/THC_and_CBD_oromucosal_s pray__Sativex%C2%AE__in_the_management_of_spasticity_associated_with_multiple_sclerosis_
Plasma cannabinoid pharmacokinetics following controlled oral delta9tetrahydrocannabinol and oromucosal cannabis extract administration.
(abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21078841/abstract/Plasma_cannabinoid_pharmaco kinetics_following_controlled_oral_delta9_tetrahydrocannabinol_and_oromucosal_cannabis_extract_admi nistration_
Memory-rescuing effects of cannabidiol in an animal model of cognitive impairment relevant to neurodegenerative disorders. (abst 2011)
The interplay of cannabinoid and NMDA glutamate receptor systems in humans: preliminary evidence of interactive effects of cannabidiol and ketamine in healthy human subjects. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21062637/abstract/The_interplay_of_cannabinoid_ and_NMDA_glutamate_receptor_systems_in_humans:_preliminary_evidence_of_interactive_effects_of_c annabidiol_and_ketamine_in_healthy_human_subjects_
Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22110202 Heterogeneity in the composition of marijuana seized in California. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21288662/abstract/Heterogeneity_in_the_composit ion_of_marijuana_seized_in_California_
Cannabidiol induced a contrasting pro-apoptotic effect between freshly isolated and precultured human monocytes. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/20471992/abstract/Cannabidiol_induced_a_contras ting_pro_apoptotic_effect_between_freshly_isolated_and_precultured_human_monocytes_
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Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21821735/abstract/Cannabidiol_a_major_phytocan nabinoid_as_a_potent_atypical_inhibitor_for_CYP2D6_
Cannabidiol (CBD) as an Anti-Arrhythmic (abst 2011)

Cannabis could help treat epilepsy #1
(news 2011) (news 2011) (news - 2011)
http://www.newkerala.com/news/world/fullnews-186693.html
Cannabis could be used to treat epilepsy #2 Cannabidiol May Fight Alzheimer's Disease
http://www.telegraph.co.uk/science/science-news/8440303/Cannabis-could-be-used-to-treat-epilepsy.html
http://www.examiner.com/medical-marijuana-in-philadelphia/cannabidiol-may-fight-alzheimer-sdisease?fb_comment=31078356
Marijuana Compound Induces Cell Death In Hard-To-Treat Brain Cancer (news 2011)
Marijuana Extract Might Help Prevent Chemotherapy-Related Nerve Pain (news 2011)
http://www.newswise.com/articles/view/580864/?sc=rsmn
Cannabinoid 'Completely' Prevents Chemotherapy-Induced Neuropathy, Study Says (news 2011) http://www.norml.org/index.cfm?Group_ID=8710 Marijuana component may ease pain from chemo therapy drugs
http://www.jpost.com/Health/Article.aspx?id=241299
(news 2011) (news 2011)
Another Study Confirms Anti-Cancer Effects of THC and CBD
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Pot Compound Exerts Anticonvulsant Effects In Animal Models Of Epilepsy (news - 2011) http://www.norml.org/index.cfm?Group_ID=8458 New research provides hope for those with epilepsy (news - 2011)
http://medicalxpress.com/news/2011-04-epilepsy.html
Cannabis Compound Induces Death Of Cells Associated With Liver Fibrosis (news 2011) http://www.norml.org/index.cfm?Group_ID=8615 Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/22231745
CANNABIDIOLIC ACID - precursor to Cannabidiol Purification and characterization of cannabidiolic-acid synthase from Cannabis sativa L.. Biochemical analysis of a novel enzyme that catalyzes the oxidocyclization of cannabigerolic acid to cannabidiolic acid. (full 1996)
http://www.jbc.org/content/271/29/17411.long
Cannabidiolic acid as a selective cyclooxygenase-2 inhibitory component in cannabis. (full 2008) http://dmd.aspetjournals.org/content/36/9/1917.long The effects of cannabidiolic acid and cannabidiol on contractility of the gastrointestinal tract of Suncus murinus. (abst 2011)
Cannabidiol May Fight Alzheimer's Disease
(news 2011)
http://www.examiner.com/medical-marijuana-in-philadelphia/cannabidiol-may-fight-alzheimer-s-disease
Contrasting protective effects of cannabinoids against oxidative stress and amyloid- evoked neurotoxicity in vitro. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/22233683
CANNABIGEROL / CBG phytocannabinoid, CB2 agonist Allergenic properties of naturally occurring cannabinoids.
(abst - 1983)
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Intraocular pressure, ocular toxicity and neurotoxicity after administration of cannabinol or cannabigerol. (abst 1984) http://www.ncbi.nlm.nih.gov/pubmed/6499952 Identification of a New Chemotype in Cannabis sativa: Cannabigerol - Dominant Plants, Biogenetic and Agronomic Prospects (abst 1987)
https://www.thieme-connect.com/DOI/DOI?10.1055/s-2006-962705
A comparison of the ocular and central effects of delta 9-tetrahydrocannabinol and cannabigerol. (abst - 1990) http://www.ncbi.nlm.nih.gov/pubmed/1965836 In vitro metabolism of cannabigerol in several mammalian species.
(abst 1990)
Boron trifluoride etherate on silica-A modified Lewis acid reagent (VII). Antitumor activity of cannabigerol against human oral epitheloid carcinoma cells. (abst - 1998)
(abst - 2000)

Patent application title: THERAPEUTIC USES OF CANNABIGEROL (full - 2010)

Evidence that the plant cannabinoid cannabigerol is a highly potent alpha2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist. (full - 2010)
Detection of cannabigerol and its presumptive metabolite in human urine after Cannabis consumption. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20614687 Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa (full 2011) http://www.jstage.jst.go.jp/article/bpb/34/5/774/_pdf
183
Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21243485 Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), (9)-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessivecompulsive behaviour. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21796370 Phytocannabinoids as novel therapeutic agents in CNS disorders
(abst 2011)
CANNABINOID HYPEREMESIS SYNDROME Cannabinoid hyperemesis: cyclical hyperemesis in association with chronic cannabis abuse (full 2004) http://gut.bmj.com/content/53/11/1566.full Cannabinoid hyperemesis: not just a problem in Adelaide Hills (letter 2005)
http://gut.bmj.com/content/54/5/731.1.full?ijkey=1efc19d4fee30ce0ca73a84272095f5ff8b63736&keytype2 =tf_ipsecsha "Cannabis hyperemesis" causation questioned. (full 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1856368/?tool=pubmed
Cannabinoid hyperemesis: marijuana puts patients in hot water.

(abst 2007)
Cannabinoid hyperemesis relieved by compulsive bathing.

(full 2009)
Cannabinoid hyperemesis. (# 1) (full 2010)

Cannabinoid Hyperemesis and Compulsive Bathing: A Case Series and Paradoxical Pathophysiological Explanation (full 2010) http://www.jabfm.org/content/23/6/790.long Cannabinoid-Induced Hyperemesis: A ConundrumFrom Clinical Recognition to Basic Science Mechanisms (abst/click for full PDF - 2010)
http://www.mdpi.com/1424-8247/3/7/2163/
184
The cannabis hyperemesis syndrome characterized by persistent nausea and vomiting, abdominal pain, and compulsive bathing associated with chronic marijuana use: a report of eight cases in the United States. (abst 2010)
Cannabinoid hyperemesis syndrome as the underlying cause of intractable nausea and vomiting. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21464265 Cannabis Hyperemesis Syndrome. (# 2)
(abst 2011) (abst 2011)
Cannabis Hyperemesis Syndrome (# 3)

Image of the month. Skin discoloration from compulsive bathing in a patient with hyperemesis syndrome. (abst 2011)
http://www.cghjournal.org/article/S1542-3565%2810%2900843-8/abstract
Cannabinoid hyperemesis syndrome inducing acute prerenal failure and electrolyte disturbance. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21877303 Cannabinoid hyperemesis syndrome: literature review and proposed diagnosis and treatment algorithm. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21886087 Cannabinoid hyperemesis syndrome: an underreported entity causing nausea and vomiting of pregnancy. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21170540 Pediatric cannabinoid hyperemesis: two cases.
(abst 2011)
Hyperemesis and a High Water Bill. Cannabinoid hyperemesis. (# 4)
(abst 2011) (abst 2012)
Cyclic vomiting syndrome and functional vomiting in adults: association with cannabinoid use in males. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/21951771
CANNABINOID RECEPTOR SYSTEM - see ENDOCANNABINOID SYSTEM, CBR
185
CANNABINOR - synthetic, CB2 agonist Pharmos Initiates Phase I Trial of CB2-Selective Drug Candidate Cannabinor (news 2005)
http://www.redorbit.com/news/health/231069/pharmos_initiates_phase_i_trial_of_cb2selective_drug_candi date_cannabinor/index.html
Cannabinoid Receptor Agonist Significantly Reduces Post-Operative Pain, Study Says (news 2007) http://norml.org/index.cfm?Group_ID=7246 Patent application title: Treatment Of Lower Urinary Tract Dysfunction With CB2Receptor-Selective Agonists (full 2009) http://www.faqs.org/patents/app/20090312414 Effects of cannabinor, a novel selective cannabinoid 2 receptor agonist, on bladder function in normal rats. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20207474 Cannabinor, a selective cannabinoid-2 receptor agonist, improves bladder emptying in rats with partial urethral obstruction. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21168864/abstract/Cannabinor_a_selective_cannab inoid_2_receptor_agonist_improves_bladder_emptying_in_rats_with_partial_urethral_obstruction_
CANNADOR - a phytocannabinoid extract in pill form A multicenter dose-escalation study of the analgesic and adverse effects of an oral cannabis extract (Cannador) for postoperative pain management. (full - 2006)
http://journals.lww.com/anesthesiology/Fulltext/2006/05000/A_Multicenter_Dose_escalation_Study_of_th e.21.aspx
Analgesic and adverse effects of an oral cannabis extract (Cannador) for postoperative pain (abst - 2006) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=184 Cannabis effective at relieving pain after major surgery
(news - 2006) (news - 2006)
Cannador: Drug from cannabis plant-extract to reduce surgery pain
http://www.ecofriend.org/entry/cannador-drug-from-cannabis-plant-extract-to-reduce-surgery-pain/
Clinical phase III study with the cannabis extract Cannador successful in multiple sclerosis (news - 2009)
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CARDIOVASCULAR - see HEART DISEASE
CARPAL TUNNEL SYNDROME Use of palmitoylethanolamide in the entrapment neuropathy of the median in the wrist. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21483401
CBR - CB1 CANNABINOID RECEPTOR -activated by THC, Anandamide, synthetics Cannabinoid Receptor Ligands (full - no date)
http://www.tocris.com/pdfs/cannabinoid_receptor_review/page_001.html
Evidence for the presence of cannabinoid CB1 receptors in mouse urinary bladder (abst 1996) http://pharmgkb.org/pmid/8864542 Cannabinoid-Induced Hypotension and Bradycardia in Rats Is Mediated by CB1-Like Cannabinoid Receptors (full - 1997)
Hypoactivity of the Spinal Cannabinoid System Results in NMDA-Dependent Hyperalgesia (full 1998) http://www.jneurosci.org/content/18/1/451.long Evidence That the Cannabinoid CB1 Receptor Is a 2-Arachidonoylglycerol Receptor (full 1999) http://www.jbc.org/content/274/5/2794.long Increased Mortality, Hypoactivity, and Hypoalgesia in Cannabinoid Cb1 Receptor Knockout Mice. (full 1999) http://www.pnas.org/content/96/10/5780.long Cannabis and cannabinoids: pharmacology and rationale for clinical use (abst 1999)
Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain. (abst - 1999)
Thujone exhibits low affinity for cannabinoid receptors but fails to evoke cannabimimetic responses. (abst 1999) http://www.ncbi.nlm.nih.gov/pubmed/10080239 Endocannabinoids and Vascular Function
(full - 2000)
187
Effects of cannabinoid receptor agonists on neuronally-evoked contractions of urinary bladder tissues isolated from rat, mouse, pig, dog, monkey and human (full - 2000)
Modulation of peristalsis by cannabinoid CB1 ligands in the isolated guinea-pig ileum (full - 2000) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1571902&tool=pmcentrez Cannabinoid CB1-mediated inhibition of stress-induced gastric ulcers in rats (abst 2000) http://www.springerlink.com/content/w3jc8rk16k9p92fl/ Inhibition of small intestinal secretion by cannabinoids is CB1 receptor-mediated in rats (abst 2000) http://www.sciencedirect.com/science/article/pii/S0014299900008438 Sex steroid influence on cannabinoid CB(1) receptor mRNA and endocannabinoid levels in the anterior pituitary gland. (abst 2000) http://www.ncbi.nlm.nih.gov/pubmed/10733937 Association study of a cannabinoid receptor gene (CNR1) polymorphism and schizophrenia (abst 2000) http://pharmgkb.org/pmid/11204352 Are Cannabinoid Receptor Knockout Mice Animal Models for Schizophrenia? (abst -2000) http://www.medical-hypotheses.com/article/S0306-9877%2800%2991261-1/abstract Delta(9)-tetrahydrocannabinol and synthetic cannabinoids prevent emesis produced by the cannabinoid CB(1) receptor antagonist/inverse agonist SR 141716A. (full 2001)
Cannabinoid CB1-receptor mediated regulation of gastrointestinal motility in mice in a model of intestinal inflammation (full - 2001)
2-Arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor (full - 2001) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC31108/ Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase (full - 2001)
Despite substantial degradation, 2-arachidonoylglycerol is a potent full efficacy agonist mediating CB(1) receptor-dependent G-protein activation in rat cerebellar membranes. (full 2001) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1572991/?tool=pubmed
188
The Central Cannabinoid Receptor Inactivation Suppresses Endocrine Reproductive Functions. (abst 2001)
Sourcing the Code: Searching for the Evolutionary Origins of Cannabinoid Receptors, Vanilloid Receptors, and Anandamide (full 2002)
Influence of the CB1 receptor antagonist, AM 251, on the regional haemodynamic effects of WIN-55212-2 or HU 210 in conscious rats (full - 2002)
Increased Severity of Stroke in CB1 Cannabinoid Receptor Knock-Out Mice (full - 2002)
http://www.jneurosci.org/cgi/content/full/22/22/9771?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabinoid&searchid=1&FIRSTINDEX=80&resourcetype=HWCIT#Top
Loss of cannabinoid CB(1) receptors in the basal ganglia in the late akinetic phase of rats with experimental Huntington's disease. (abst 2002)
The endogenous cannabinoid system controls extinction of aversive memories. (abst - 2002) http://www.ncbi.nlm.nih.gov/pubmed/12152079 Association of a CB1 cannabinoid receptor gene (CNR1) polymorphism with severe alcohol dependence. (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/11841893 CB1 cannabinoid receptor antagonism promotes remodeling and cannabinoid treatment prevents endothelial dysfunction and hypotension in rats with myocardial infarction (full - 2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573770/?tool=pmcentrez The Endogenous Cannabinoid System Regulates Seizure Frequency and Duration in a Model of Temporal Lobe Epilepsy (full - 2003)
Cannabinoid1 receptor in the dorsal vagal complex modulates lower oesophageal sphincter relaxation in ferrets (full 2003) http://jp.physoc.org/content/550/1/149.full
189
Inhibitory effects of cannabinoid CB1 receptor stimulation on tumor growth and metastatic spreading: actions on signals involved in angiogenesis and metastasis1 (full - 2003) http://www.fasebj.org/cgi/reprint/17/12/1771 High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma (abst 2003)
Differential distribution of functional cannabinoid CB1 receptors in the mouse gastroenteric tract. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12505538 Milk intake and survival in newborn cannabinoid CB1 receptor knockout mice: evidence for a "CB3" receptor. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12568912 Expression of functionally active cannabinoid receptor CB1 in the human prostate gland (abst 2003) http://onlinelibrary.wiley.com/doi/10.1002/pros.10165/abstract Structure, expression and regulation of the cannabinoid receptor gene (CB1) in Huntington's disease transgenic mice. (full 2004)
Presynaptic cannabinoid CB1 receptors are involved in the inhibition of the neurogenic vasopressor response during septic shock in pithed rats (full - 2004)
Defective adult neurogenesis in CB1 cannabinoid receptor knockout mice. (full - 2004)
CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity (full - 2004)
Delayed onset of Huntington's disease in mice in an enriched environment correlates with delayed loss of cannabinoid CB1 receptors. (abst 2004)
Tourette syndrome is not caused by mutations in the central cannabinoid receptor (CNR1) gene. (abst - 2004) http://www.ncbi.nlm.nih.gov/pubmed/15108190
190
Cb(1) Receptor Mediation of Cannabinoid Behavioral Effects in Male and Female Rats. (abst - 2004)
http://medical-journals.healia.com/doc/14991224/CB1-receptor-mediation-of-cannabinoid-behavioraleffects-in-male-and-female-rats
Enhancing Cannabinoid Neurotransmission Augments the Extinction of Conditioned Fear (full - 2005) http://www.nature.com/npp/journal/v30/n3/full/1300655a.html Depression in Parkinson's disease is related to a genetic polymorphism of the cannabinoid receptor gene (CNR1) (full - 2005)
http://www.nature.com/tpj/journal/v5/n2/full/6500301a.html
Synergistic Interactions between Cannabinoids and Environmental Stress in the Activation of the Central Amygdala (full - 2005)
The cannabinoid 1 receptor antagonist, AM251, prolongs the survival of rats with severe acute pancreatitis. (full - 2005) http://www.jstage.jst.go.jp/article/tjem/207/2/207_99/_article Direct cerebrovascular effects of CB1 receptor activation by the synthetic endocannabinoid HU-210 in vivo (full - 2005)
http://www.nature.com/jcbfm/journal/v25/n1s/full/9591524.0581a.html
CB1 cannabinoid receptor-mediated modulation of food intake in mice (full - 2005)

Evidence that the plant cannabinoid 9-tetrahydrocannabivarin is a cannabinoid CB1 and CB2 receptor antagonist (full - 2005)
Early age-related cognitive impairment in mice lacking cannabinoid CB1 receptors. (full 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266095/?tool=pubmed
191
Antidepressant-like Activity and Modulation of Brain Monoaminergic Transmission by Blockade of Anandamide Hydrolysis. (full 2005)
Ethanol Induces Higher Bec in Cb1 Cannabinoid Receptor Knockout Mice While Decreasing Ethanol Preference. (full 2005)
The Endogenous Cannabinoid System. Therapeutic Implications for Neurologic and Psychiatric Disorders (abst 2005)
http://medical-journals.healia.com/doc/15776259/The-endogenous-cannabinoid-system.-Therapeuticimplications-for-neurologic-and-psychiatric-disorders
The endocannabinoid system drives neural progenitor proliferation.

(full 2005)
(full - 2005)
Cannabinoid-receptor 1 null mice are susceptible to neurofilament damage and caspase 3 activation. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/15953683 Finding of endocannabinoids in human eye tissues: implications for glaucoma. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/15823551 Marijuana May Grow Neurons in the Brain (news - 2005)
http://www.medpagetoday.com/Psychiatry/AnxietyStress/1934
The Endocannabinoid System Controls Key Epileptogenic Circuits in the Hippocampus (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769341/?tool=pmcentrez AM 251 produces sustained reductions in food intake and body weight that are resistant to tolerance and conditioned taste aversion (full - 2006)
Activation of the Cannabinoid Type-1 Receptor Mediates the Anticonvulsant Properties of Cannabinoids in the Hippocampal Neuronal Culture Models of Acquired Epilepsy and Status Epilepticus (full - 2006)
http://jpet.aspetjournals.org/content/317/3/1072.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext =cannabinoid&searchid=1&FIRSTINDEX=320&resourcetype=HWCIT#ref-list-1
Activation of G-proteins in brain by endogenous and exogenous cannabinoids. (full 2006) http://www.ncbi.nlm.nih.gov/pubmed/16584117 The Cannabinoid Cb1 Receptor Antagonist Rimonabant Attenuates the Hypotensive Effect of Smoked Marijuana in Male Smokers. (full 2006)
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Cannabinoid (CB1) Receptor Activation Inhibits Trigeminovascular Neurons (full - 2006)

http://jpet.aspetjournals.org/content/320/1/64.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=c annabis&searchid=1&FIRSTINDEX=3680&resourcetype=HWCIT
Cannabinoid CB1 receptor antagonists cause status epilepticus-like activity in the hippocampal neuronal culture model of acquired epilepsy (full - 2006)
Antinociceptive effect of cannabinoid agonist WIN 55,2122 in rats with a spinal cord injury (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1861843/?tool=pmcentrez Involvement of Neuronal Cannabinoid Receptor CB1 in Regulation of Bone Mass and Bone Remodeling (full - 2006)
Inhibitory effects of cannabinoid CB1 receptor stimulation on tumor growth and metastatic spreading: actions on signals involved in angiogenesis and metastasis (full - 2006)
http://www.fasebj.org/cgi/reprint/021129fjev1?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=cannabinoid&andorexactfulltext=and&s earchid=1&FIRSTINDEX=10&sortspec=relevance&resourcetype=HWCIT
Cannabinoid CB1 Receptor Mediates Fear Extinction via Habituation-Like Processes (full - 2006)
Evolutionary Origins of the Endocannabinoid System.
(abst 2006)
http://medical-journals.healia.com/doc/16434153/Evolutionary-origins-of-the-endocannabinoid-system
Science: Cannabinoids reduce inflammation of the bowel in animal model (news - 2006)
PET imaging of cerebral cannabinoid CB1 receptors with [11C]JHU75528 (news 2006) http://www.news-medical.net/news/2006/06/06/18312.aspx The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling. (full - 2007) http://www.fasebj.org/cgi/content/full/22/1/285 Anandamide Regulates Keratinocyte Differentiation by Inducing DNA Methylation in a CB1 Receptor-dependent Manner (full 2007)
CANNABINOID-INDUCED HYPERPHAGIA: CORRELATION WITH INHIBITION OF PROOPIOMELANOCORTIN NEURONS? (full - 2007)

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Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234438/ The CB1 Cannabinoid Receptor Mediates Excitotoxicity-induced Neural Progenitor Proliferation and Neurogenesis (full - 2007) http://www.jbc.org/content/282/33/23892.full Expression of Cannabinoid CB1 Receptors in Models of Diabetic Neuropathy (full - 2007)
Cannabinoid CB1 and CB2 Receptors and Fatty Acid Amide Hydrolase Are Specific Markers of Subtypes in Human Multiple Sclerosis (full - 2007)
http://www.jneurosci.org/cgi/content/full/27/9/2396?maxtoshow=&hits=10&RESULTFORMAT=&fulltext =cannabinoid&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype =HWCIT
(full - 2007)
Control of spasticity in a multiple sclerosis model is mediated by CB1, not CB2, cannabinoid receptors. (full - 2007)
Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190006/?tool=pmcentrez Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro (full - 2007)
Anandamide Regulates Keratinocyte Differentiation by Inducing DNA Methylation in a CB1 Receptor-dependent Manner (full 2007) http://www.jbc.org/content/283/10/6005.full The endocannabinoid system and neurogenesis in health and disease.
(abst - 2007)
The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17583570 Repeated Treatment with Cannabidiol but Not Delta9-tetrahydrocannabinol Has a Neuroprotective Effect Without the Development of Tolerance (abst - 2007)
194
Cannabinoid CB1 receptors in the paraventricular nucleus and central control of penile erection: immunocytochemistry, autoradiography and behavioral studies (abst 2007)
Whole-Body Biodistribution and Radiation Dosimetry of the Human Cannabinoid Type1 Receptor Ligand ^sup 18^F-MK-9470 in Healthy Subjects (full - 2008)
http://findarticles.com/p/articles/mi_hb5979/is_200803/ai_n32266209/
Genetic Variations at the Endocannabinoid Type 1 Receptor Gene (CNR1) Are Associated with Obesity Phenotypes in Men (full - 2008)
http://jcem.endojournals.org/cgi/content/full/92/6/2382
Cannabinoid Receptor 1 Gene Association With Nicotine Dependence
(full - 2008)
http://archpsyc.amaassn.org/cgi/content/full/65/7/816?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&se archid=1&FIRSTINDEX=0&resourcetype=HWCIT
Association of the Cannabinoid Receptor Gene (CNR1) With ADHD and Post-Traumatic Stress Disorder (full - 2008)
The cannabinoid CB1 receptor antagonist CE prolongs spatial memory duration in a rat delayed radial arm maze memory task (full - 2008)
Cannabinoid Modulation of Cutaneous A{delta} Nociceptors During Inflammation (full - 2008) http://jn.physiology.org/cgi/reprint/100/5/2794 Topical WIN55212-2 Alleviates Intraocular Hypertension in Rats Through a CB1 Receptor-Mediated Mechanism of Action (full - 2008)
The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: 9tetrahydrocannabinol, cannabidiol and 9-tetrahydrocannabivarin (full - 2008)
Loss of Cannabinoid Receptor CB1 Induces Preterm Birth

(full - 2008)
Endocannabinoids and cannabinoid receptors in ischaemiareperfusion injury and preconditioning (full - 2008)
Pharmacological Inhibition of CB1 Cannabinoid Receptor Protects Against DoxorubicinInduced Cardiotoxicity (full - 2008) http://content.onlinejacc.org/cgi/content/full/50/6/528 Cannabinoid receptors and the regulation of bone mass (full - 2008)
195

(full - 2008)
Cannabinoid CB1 Receptors Are Expressed by Parietal Cells of the Human Gastric Mucosa (full 2008) http://jhc.sagepub.com/content/56/5/511.full Feeding induced by cannabinoids is mediated independently of the melanocortin system. (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386290/?tool=pubmed Design Logic of a Cannabinoid Receptor Signaling Network That Triggers Neurite Outgrowth (full 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776723/?tool=pubmed Altered presymptomatic AMPA and cannabinoid receptor trafficking in motor neurons of ALS model mice: implications for excitotoxicity. (abst - 2008)
Dysregulation of the endocannabinoid system in obesity. (abst 2008)

High concentrations of cannabinoids activate apoptosis in human U373MG glioma cells. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18615640 Turned-Off Cannabinoid Receptor Turns On Colorectal Tumor Growth (news - 2008) http://www.sciencedaily.com/releases/2008/08/080801074056.htm Cannabinoid cell surface receptor plays a tumor-suppressing role in human colorectal cancer (news 2008) http://www.news-medical.net/news/2008/08/03/40485.aspx Actions of delta-9-tetrahydrocannabinol in cannabis (full - 2009)
Cannabinoid Receptor 1 Binding Activity and Quantitative Analysis of Cannabis sativa L. Smoke and Vapor (full 2009) http://www.jstage.jst.go.jp/article/cpb/58/2/201/_pdf Endocannabinoids in the rat basolateral amygdala enhance memory consolidation and enable glucocorticoid modulation of memory (full - 2009)
196
Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma (full - 2009) http://mct.aacrjournals.org/content/8/7/1838.full Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity. (full 2009) http://brain.oxfordjournals.org/content/132/11/3152.long Effects of the cannabinoid CB1 receptor antagonist AM 251 on the reinstatement of nicotine-conditioned place preference by drug priming in rats. (full - 2009)
Cannabinoid receptors in brain: pharmacogenetics, neuropharmacology, neurotoxicology, and potential therapeutic applications. (abst - 2009)
Long-term consequences of URB597 administration during adolescence on cannabinoid CB1 receptor binding in brain areas. (abst 2009)
Cannabinoid receptors in brain: pharmacogenetics, neuropharmacology, neurotoxicology, and potential therapeutic applications (abst 2009) http://pharmgkb.org/pmid/19897083 Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease. (abst 2009)

(abst 2009) (news 2009)
The cannabinoid system: cannabinoids and receptors
http://www.examiner.com/health-science-in-vancouver/the-cannabinoid-system-cannabinoids-andreceptors
Understanding Functional Residues of the Cannabinoid CB1 for Drug Discovery. (full 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980537/?tool=pubmed Cannabinoid receptor 1 binding activity and quantitative analysis of Cannabis sativa L. smoke and vapor. (full - 2010) http://www.jstage.jst.go.jp/article/cpb/58/2/58_201/_article
197
CannabinoidDopamine Interaction in the Pathophysiology and Treatment of CNS Disorders (full 2010) http://onlinelibrary.wiley.com/doi/10.1111/j.1755-5949.2010.00144.x/full Voluntary Exercise and Sucrose Consumption Enhance Cannabinoid CB1 Receptor Sensitivity in the Striatum (full - 2010)
AAV vector-mediated overexpression of CB1 cannabinoid receptor in pyramidal neurons of the hippocampus protects against seizure-induced excitoxicity. (full 2010)
Widespread Decrease of Type 1 Cannabinoid Receptor Availability in Huntington Disease In Vivo (full 2010) http://jnm.snmjournals.org/cgi/content/full/51/9/1413 JWH018, a common constituent of 'Spice' herbal blends, is a potent and efficacious cannabinoid CB(1) receptor agonist. (full - 2010)
Attenuation of morphine antinociceptive tolerance by a CB(1) receptor agonist and an NMDA receptor antagonist: Interactive effects. (full 2010)
Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines. (full 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930808/?tool=pubmed Genes differentially expressed in CB1 knockout mice: involvement in the depressive-like phenotype. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20692131 Pharmacological exploitation of the endocannabinoid system: new perspectives for the treatment of depression and anxiety disorders? (abst 2010)
198
Expression of cannabinoid receptors in human kidney.

(abst 2010)
Abnormal sensitivity of cannabinoid CB1 receptors in the striatum of mice with experimental amyotrophic lateral sclerosis. (abst 2010)
Loss of cannabinoid CB1 receptor expression in the 6-hydroxydopamine-induced nigrostriatal terminal lesion model of Parkinson's disease in the rat. (abst 2010)
Delta9-tetrahydrocannabinol is a full agonist at CB1 receptors on GABA neuron axon terminals in the hippocampus. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20417220/abstract/Delta9_tetrahydrocannabinol_is _a_full_agonist_at_CB1_receptors_on_GABA_neuron_axon_terminals_in_the_hippocampus_
(abst - 2010)
A common variation in the cannabinoid 1 receptor (CNR1) gene is associated with preeclampsia in the Central European population. (abst - 2010)
Substantially altered expression pattern of cannabinoid receptor 2 and activated endocannabinoid system in patients with severe heart failure. (abst 2010)
Expression of cannabinoid receptor I during mice skin incised wound healing course (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20967946 Dynamic changes of CB1-receptor expression in hippocampi of epileptic mice and humans. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20618415 Study shows direct cellular interaction between endocannabinoids and alcohol in the brain (news - 2010)
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Increased Expression of Cannabinoid CB(1) Receptors in Achilles Tendinosis. (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169627/?tool=pubmed WIN55,212-2 induces cytoplasmic vacuolation in apoptosis-resistant MCL cells. (full 2011) http://www.nature.com/cddis/journal/v2/n11/full/cddis2011106a.html Local activation of cannabinoid CB1 receptors in the urinary bladder reduces the inflammation-induced sensitization of bladder afferents. (full 2011)
Cannabinoid CB1 receptor antagonists modulate transport activity of multidrug resistance-associated proteins MRP1, MRP2, MRP3, and MRP4 (full 2011)
http://dmd.aspetjournals.org/content/early/2011/04/21/dmd.110.037812.full.pdf+html?maxtoshow=&hits=8 0&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcet ype=HWCIT
Role of CB1 cannabinoid receptors on GABAergic neurons in brain aging

(full 2011)

Variation in the human Cannabinoid Receptor (CNR1) gene modulates gaze duration for happy faces. (full 2011) http://www.molecularautism.com/content/pdf/2040-2392-2-10.pdf Deficiency of Dietary Omega-3 May Explain Depressive Behaviors (summary- 2011)
http://www.thefreelibrary.com/Deficiency+of+Dietary+Omega-3+May+Explain+Depressive+Behaviors.a0248155576
Possible involvement of the endocannabinoid system in memory modulation effect of general anesthetics (abst - 2011)
http://www.unboundmedicine.com/medline/ebm/record/21555187/abstract/Possible_involvement_of_the_e ndocannabinoid_system_in_memory_modulation_effect_of_general_anesthetics_
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Genetic and pharmacological inactivation of cannabinoid CB1 receptor inhibits angiogenesis. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21460248/abstract/Genetic_and_pharmacological_ inactivation_of_cannabinoid_CB1_receptor_inhibits_angiogenesis_
Deficiency of type 1 cannabinoid receptors worsens acute heart failure induced by pressure overload in mice. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21785110 Cannabidiol as an anti-arrhythmic, the role of the CB1 receptors. (abst 2011)
Regional changes in type 1 cannabinoid receptor availability in Parkinson's disease in vivo (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21459482/abstract/Regional_changes_in_type_1_c annabinoid_receptor_availability_in_Parkinson%27s_disease_in_vivo_
Cannabinoid Receptor Type 1 Protects Nigrostriatal Dopaminergic Neurons against MPTP Neurotoxicity by Inhibiting Microglial Activation. (abst 2011)
Effects of cannabinoid CB(1) receptor agonism and antagonism on SKF81297-induced dyskinesia and haloperidol-induced dystonia in Cebus apella monkeys. (abst 2011)
Early onset of aging-like changes is restricted to cognitive abilities and skin structure in Cnr1(-/-) mice. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/20724033 The G protein-coupled cannabinoid-1 (CB(1)) receptor of mammalian brain: Inhibition by phthalate esters in vitro. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21763743 Residual effects of focal brain ischaemia upon cannabinoid CB(1) receptor density and functionality in female rats. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21145311 Alkamides and a neolignan from Echinacea purpurea roots and the interaction of alkamides with G-protein-coupled cannabinoid receptors. (abst 2011)
Brain Type 1 Cannabinoid Receptor Availability in Patients with Anorexia and Bulimia Nervosa. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21718968 Increment of hypothalamic 2-arachidonoylglycerol induces the preference for a high-fat diet via activation of cannabinoid 1 receptors (abst 2011)
201
Type I cannabinoid receptor trafficking: all roads lead to lysosome.

(abst 2011) (abst 2011)
Intact cannabinoid CB1 receptors in the Alzheimer's disease cortex.

Endocannabinoid CB1 receptors modulate visual output from the thalamus. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21773721 Cannabinoids and emotionality: a neuroanatomical perspective.
(abst 2011)
The Dopamine and Cannabinoid Interaction in the Modulation of Emotions and Cognition: Assessing the Role of Cannabinoid CB1 Receptor in Neurons Expressing Dopamine D1 Receptors. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21887137 Loss of striatal cannabinoid CB1 receptor function in attention-deficit/hyperactivity disorder mice with point-mutation of the dopamine transporter. (abst 2011)
Activation of spinal and supraspinal cannabinoid-1 receptors leads to antinociception in a rat model of neuropathic spinal cord injury pain. (abst 2011)
-Tocopherol and -tocopheryl phosphate interact with the cannabinoid system in the rodent hippocampus. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21843633 Interictal Type 1 Cannabinoid Receptor Binding is Increased in Female Migraine Patients. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22077199 Gender-dependent increases with healthy aging of the human cerebral cannabinoid-type 1 receptor binding using [(18)F]MK-9470 PET. (abst 2011)
In vivo activation of endocannabinoid system in temporal lobe epilepsy with hippocampal sclerosis. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21303859 Cannabinoid Receptor Type 1 (CB1) Activation Inhibits Small GTPase RhoA Activity and Regulates Motility of Prostate Carcinoma Cells. (abst 2011)
ENDOGENOUS CANNABINOID SYSTEM REGULATES INTESTINAL BARRIER FUNCTION IN VIVO THROUGH CANNABINOID TYPE 1 RECEPTOR ACTIVATION (abst 2011)
202
Impaired hippocampal glucoregulation in the cannabinoid CB(1) receptor knockout mice as revealed by an optimized in vitro experimental approach. (abst 2011)
Sexually dimorphic effects of cannabinoid compounds on emotion and cognition. (abst - 2011)
http://www.unboundmedicine.com/medline/ebm/record/21991251/abstract/Sexually_dimorphic_effects_of _cannabinoid_compounds_on_emotion_and_cognition_
CB1 receptors mediate rimonabant-induced pruritic responses in mice: investigation of locus of action. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21340468/abstract/CB1_receptors_mediate_rimon abant_induced_pruritic_responses_in_mice:_investigation_of_locus_of_action_
The cannabinoid type-1 receptor carboxyl-terminus, more than just a tail.
(abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21244428/abstract/The_cannabinoid_type_1_recep tor_carboxyl_terminus_more_than_just_a_tail_
Chronic -tetrahydrocannabinol treatment in rhesus monkeys: differential tolerance and cross-tolerance among cannabinoids. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21091643/abstract/Chronic_%CE%94%E2%81%B 9_tetrahydrocannabinol_treatment_in_rhesus_monkeys:_differential_tolerance_and_cross_tolerance_amon g_cannabinoids_
CB1 cannabinoid receptor mediates glucocorticoid effects on hormone secretion induced by volume and osmotic changes. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22211674 Endogenously generated 2-arachidonoylglycerol plays an inhibitory role in bombesininduced activation of central adrenomedullary outflow in rats. (abst 2011)
Biosynthesis and degradation of the endocannabinoid 2-arachidonoylglycerol. (full 2011) http://onlinelibrary.wiley.com/doi/10.1002/biof.131/full Association between a cannabinoid receptor gene (CNR1) polymorphism and cannabinoid-induced alterations of the auditory event-related P300 potential. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21513772/abstract/Association_between_a_cannab inoid_receptor_gene__CNR1__polymorphism_and_cannabinoid_induced_alterations_of_the_auditory_eve nt_related_P300_potential_
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Unbalance of CB1 receptors expressed in GABAergic and glutamatergic neurons in a transgenic mouse model of Huntington's disease. (abst 2011)
Resorcinol-sn-Glycerol Derivatives: Novel 2-Arachidonoylglycerol Mimetics Endowed with High Affinity and Selectivity for Cannabinoid Type 1 Receptor. (abst 2011)
The genetic basis of the endocannabinoid system and drug addiction in humans (abst 2011) http://jop.sagepub.com/content/early/2011/09/20/0269881111416689 The G protein-coupled cannabinoid-1 (CB(1)) receptor of mammalian brain: Inhibition by phthalate esters in vitro. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21763743 Upregulation of cannabinoid type 1 receptors in dopamine D2 receptor knockout mice is reversed by chronic forced ethanol consumption. (full 2012)
JWH-018 and JWH-073: {Delta}9-Tetrahydrocannabinol-Like Discriminative Stimulus Effects in Monkeys. (abst 2012)
http://www.unboundmedicine.com/medline/ebm/record/21965552/abstract/JWH_018_and_JWH_073:_%7 BDelta%7D9_Tetrahydrocannabinol_Like_Discriminative_Stimulus_Effects_in_Monkeys_
The inverse agonist effect of rimonabant on G protein activation is not mediated by the cannabinoid CB1 receptor: Evidence from postmortem human brain. (abst 2012)
Dietary conditions and highly palatable food access alter rat cannabinoid receptor expression and binding density. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/22005165 Opposing Roles for Cannabinoid Receptor Type-1 (CB(1)) and Transient Receptor Potential Vanilloid Type-1 Channel (TRPV1) on the Modulation of Panic-Like Responses in Rats. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/21937980 Extinction learning of rewards in the rat: is there a role for CB1 receptors? (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/21519986 Tolerance to cannabinoid-induced behaviors in mice treated chronically with ethanol. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/21701813 The cannabinoid receptor CB inverse agonist AM251 potentiates the anxiogenic activity of urocortin I in the basolateral amygdala. (abst 2012)
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Cannabinoid Receptor Function is Altered by Nutrionally Deficient Diet
(news 2012)
http://www.examiner.com/medical-marijuana-in-philadelphia/cannabinoid-receptor-function-is-altered-bynutrionally-deficient-diet
CBR - CB2 CANNABINOID RECEPTOR - no "high", activated by THC, Anandamide, 2 -AG Cannabinoid Receptor Ligands (full - no date) (abst 1999)

Immunomodulation by Cannabinoids is Absent in Mice Deficient for the Cannabinoid Cb(2) Receptor. (abst 2000)
Involvement of central and peripheral cannabinoid receptors in the regulation of heart resistance to arrhythmogenic effects of epinephrine. (abst - 2000)
Inhibition of Glioma Growth in Vivo by Selective Activation of the CB2 Cannabinoid Receptor1 (full - 2001) http://cancerres.aacrjournals.org/cgi/reprint/61/15/5784.pdf Sourcing the Code: Searching for the Evolutionary Origins of Cannabinoid Receptors, Vanilloid Receptors, and Anandamide (full 2002)
Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease (full - 2002)
CB2 cannabinoid receptor agonists: pain relief without psychoactive effects? (abst - 2002) http://www.ncbi.nlm.nih.gov/pubmed/12550743 Lymphoma may be slowed by cannabis (news - 2002)
http://marijuana-ro.com/medical-usage/lymphoma-may-be-slowed-by-cannabis.html
Cannabinoid CB2 Receptors and Fatty Acid Amide Hydrolase Are Selectively Overexpressed in Neuritic Plaque-Associated Glia in Alzheimer's Disease Brains (full 2003)
http://www.jneurosci.org/content/23/35/11136.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext= cannabinoid&searchid=1&FIRSTINDEX=80&resourcetype=HWCIT
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Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: Pain inhibition by receptors not present in the CNS (full - 2003)
Inhibition of guinea-pig and human sensory nerve activity and the cough reflex in guineapigs by cannabinoid (CB2) receptor activation. (full - 2003)
Cannabinoids and intestinal motility: welcome to CB2 receptors

(full - 2004)
Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation (full 2005) http://www.springerlink.com/content/tq777102q4185073/fulltext.html Cannabinoid receptor type 2 gene is associated with human osteoporosis (full - 2005)
http://hmg.oxfordjournals.org/cgi/content/full/14/22/3389?maxtoshow=&hits=80&RESULTFORMAT=&f ulltext=cannabinoid&searchid=1&FIRSTINDEX=400&resourcetype=HWCIT
Cannabidiol inhibits human glioma cell migration through a cannabinoid receptorindependent mechanism (full - 2005)
CB2 cannabinoid receptors in trabecular meshwork cells mediate JWH015-induced enhancement of aqueous humor outflow facility. (full - 2005)
http://www.iovs.org/content/46/6/1988.long
Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice (full - 2005) http://www.nature.com/nature/journal/v434/n7034/full/nature03389.html
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Identification and functional characterization of brainstem cannabinoid CB2 receptors. (full- 2005) http://www.sciencemag.org/content/310/5746/329.full Marijuana May Grow Neurons in the Brain (news - 2005)
Cannabidiol-Induced Apoptosis in Human Leukemia Cells: A Novel Role of Cannabidiol in the Regulation of p22phox and Nox4 Expression (full - 2006)
Non-psychoactive CB2 cannabinoid agonists stimulate neural progenitor proliferation (full - 2006)
http://www.fasebj.org/cgi/content/full/20/13/2405?maxtoshow=&hits=10&RESULTFORMAT=&fulltext= cannabis&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HW CIT
In vitro pharmacological characterization of AM1241: a protean agonist at the cannabinoid CB2 receptor? (full - 2006)
Peripheral cannabinoid receptor, CB2, regulates bone mass

(full - 2006)
Signaling pathways involved in the cardioprotective effects of cannabinoids. (full - 2006) http://www.jstage.jst.go.jp/article/jphs/102/2/155/_pdf Alkylamides from Echinacea are a new class of cannabinomimetics. Cannabinoid type 2 receptor-dependent and -independent immunomodulatory effects. (full 2006)
New Natural Noncannabinoid Ligands for Cannabinoid Type-2 (CB2) Receptors (abst - 2006) http://informahealthcare.com/doi/abs/10.1080/10799890600942674 Delta-9-tetrahydrocannabinol protects cardiac cells from hypoxia via CB2 receptor activation and nitric oxide production (abst - 2006)
http://www.ingentaconnect.com/content/klu/mcbi/2006/00000283/F0020001/00002346
(abst 2006)
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Towards a therapeutic use of selective CB2 cannabinoid receptor ligands for atherosclerosis. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/19804131 Researchers from the Hebrew University Discover New Drug for Osteoporosis (news 2006)
http://news.softpedia.com/news/Researchers-From-the-Hebrew-University-Discover-New-Drug-forOsteoporosis-15808.shtml
Activation of CB2 receptor attenuates bone loss in osteoporosis
(news - 2006)
Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228252/?tool=pmcentrez Cannabinoid CB1 and CB2 Receptors and Fatty Acid Amide Hydrolase Are Specific Markers of Plaque Cell Subtypes in Human Multiple Sclerosis (full - 2007)
CB2 cannabinoid receptors as an emerging target for demyelinating diseases: from neuroimmune interactions to cell replacement strategies (full - 2007)
Spinal cannabinoid receptor type 2 activation reduces hypersensitivity and spinal cord glial activation after paw incision. (full - 2007)
http://journals.lww.com/anesthesiology/pages/articleviewer.aspx?year=2007&issue=04000&article=00021 &type=abstract
Cannabinoid CB2 receptor activation decreases cerebral infarction in a mouse focal ischemia/reperfusion model (full - 2007)

(full - 2007)
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Potential role for CB2 selective ligands as immunosuppressive agents

(full - 2007)
Cannabinoid CB2 receptors: a therapeutic target for the treatment of inflammatory and neuropathic pain (full - 2007)
CB2 cannabinoid receptors promote mouse neural stem cell proliferation.

(abst 2007)
Cannabinoids for the treatment of inflammation.
(abst - 2007)
Cannabinoid CB2 receptor activation prevents bronchoconstriction and airway oedema in a model of gastro-oesophageal reflux (abst - 2007)
Role of cannabinoid CB2 receptors in glucose homeostasis in rats

(abst 2007)
The cannabinoid CB(2) receptor: a good friend in the gut.

(abst 2007)
Involvement of cannabinoid CB2 receptor in alcohol preference in mice and alcoholism in humans (abst 2007) http://pharmgkb.org/pmid/17189959 Cannabinoids stimulate fibroblastic colony formation by bone marrow cells indirectly via CB2 receptors. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17205329 CB2 receptors in reproduction (full - 2008) (full - 2008)

Cannabinoid receptor 2 is increased in acutely and chronically inflamed bladder of rats (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592089/?tool=pmcentrez
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The CB2 Cannabinoid Receptor Controls Myeloid Progenitor Trafficking INVOLVEMENT IN THE PATHOGENESIS OF AN ANIMAL MODEL OF MULTIPLE SCLEROSIS (full - 2008) http://www.jbc.org/content/283/19/13320.long Cannabinoid receptors and the regulation of bone mass (full - 2008)
Pleiotropic effects of the CB2 cannabinoid receptor activation on human monocyte migration: implications for atherosclerosis and inflammatory diseases (full 2008)
Crucial Role of CB2 Cannabinoid Receptor in the Regulation of Central Immune Responses during Neuropathic Pain (full - 2008)
Cannabinoid CB2 receptors in the enteric nervous system modulate gastrointestinal contractility in lipopolysaccharide-treated rats (full - 2008)
Cannabinoid CB2 receptors in the gastrointestinal tract: a regulatory system in states of inflammation. (full 2008)
Endocannabinoids and Liver Disease. III. Endocannabinoid effects on immune cells: implications for inflammatory liver diseases (full - 2008)
Regression of Fibrosis after Chronic Stimulation of Cannabinoid CB2 Receptor in Cirrhotic Rats (full - 2008)
http://jpet.aspetjournals.org/content/324/2/475.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext= cannabinoid&searchid=1&FIRSTINDEX=320&resourcetype=HWCIT#content-block
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CB2 receptors as new therapeutic targets for liver diseases.

(full - 2008)
The CB(2) cannabinoid receptor controls myeloid progenitor trafficking: involvement in the pathogenesis of an animal model of multiple sclerosis. (full - 2008)
Crucial role of CB(2) cannabinoid receptor in the regulation of central immune responses during neuropathic pain. (full - 2008) http://www.jneurosci.org/cgi/content/full/28/46/12125 Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling. (full 2008)
http://www.fasebj.org/content/22/10/3685.long

(abst - 2008)
Behavioral effects of CB2 cannabinoid receptor activation and its influence on food and alcohol consumption. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18991890 Glial expression of cannabinoid CB(2) receptors and fatty acid amide hydrolase are beta amyloid-linked events in Down's syndrome. (abst 2008)
New Cannabis-Like Drugs Could Block Pain Without Affecting Brain, Says Study (news - 2008) http://www.sciencedaily.com/releases/2008/09/080912091728.htm Ulcerative Colitis Induces Changes on the Expression of the Endocannabinoid System in the Human Colonic Tissue (full - 2009)
Modulation of cannabinoid receptor activation as a neuroprotective strategy for EAE and stroke. (full 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855650/?tool=pubmed Emerging Role of the CB2 Cannabinoid Receptor in Immune Regulation and Therapeutic Prospects (full - 2009)
The cannabinoid receptor 2 is critical for the host response to sepsis. (full 2009)
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Endocannabinoids and Their Receptors as Targets for Obesity Therapy (full - 2009) http://endo.endojournals.org/cgi/content/full/150/6/2531#top Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)Methanandamide and JWH-015: Involvement of CB2 (full - 2009)
Activation of the cannabinoid 2 receptor (CB2) protects against experimental colitis. (full - 2009) http://onlinelibrary.wiley.com/doi/10.1002/ibd.20960/full Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity (full - 2009) http://brain.oxfordjournals.org/content/132/11/3152.long Cannabinoid CB2 receptor agonists protect the striatum against malonate toxicity: relevance for Huntington's disease. (abst - 2009)
Protracted cannabinoid administration elicits antidepressant behavioral responses in rats: role of gender and noradrenergic transmission. (abst - 2009)
Distribution and function of cannabinoid receptors 1 and 2 in the rat, monkey and human bladder. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19237169 The cannabinoid R+ methanandamide induces IL-6 secretion by prostate cancer PC3 cells. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19908944 The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages. (abst - 2009)
Cannabinoid receptors in brain: pharmacogenetics, neuropharmacology, neurotoxicology, and potential therapeutic applications (abst 2009) http://pharmgkb.org/pmid/19897083 CB2 cannabinoid receptor activation is cardioprotective in a mouse model of ischemia/reperfusion (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19162037 CB2 receptor activation attenuates microcirculatory dysfunction during cerebral ischemic/reperfusion injury. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19332079
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The influence of cannabinoid CB2 receptor in adult rat mesenchymal stem cell viability (abst 2009)
http://www.physoc.org/custom2/publications/proceedings/archive/article.asp?ID=Proc%20Physiol%20Soc %2015PC171
The role of CB2 cannabinoid receptor and Leptin in hepatic fibrosis via lymphocyte alterations and HSC phagocytosis (abst 2009)
http://www.docstoc.com/docs/76792678/The-role-of-CB2-cannabinoid-receptor-and-Leptin-in-hepatic-
Cannabis may apparently stop prostate cancer growth The cannabinoid system: cannabinoids and receptors
(news - 2009) (news 2009)
http://www.healthjockey.com/2009/08/21/cannabis-may-apparently-stop-prostate-cancer-growth/
CB2: a cannabinoid receptor with an identity crisis.
(full 2010)
Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type I diabetic peripheral neuropathic pain (full - 2010)
Activation of cannabinoid 2 receptors protects against cerebral ischemia by inhibiting neutrophil recruitment. (full 2010) http://www.fasebj.org/content/24/3/788.long Brain CB2 Receptors: Implications for Neuropsychiatric Disorders
(full 2010) (full 2010)
Patent 7741365 Peripheral cannabinoid receptor (CB2) selective ligands

Cannabinoid-2 receptor limits inflammation, oxidative/nitrosative stress, and cell death in nephropathy. (full 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869084/?tool=pubmed Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non-small cell lung cancer growth and metastasis (full - 2011)
A nonsynonymous polymorphism in cannabinoid CB2 receptor gene is associated with eating disorders in humans and food intake is modified in mice by its ligands. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/19768813 Brain cannabinoid CB2 receptor in schizophrenia.
(abst 2010)
The cannabinoid receptor type 2 is time-dependently expressed during skeletal muscle wound healing in rats (abst - 2010) http://www.ncbi.nlm.nih.gov/sites/pubmed
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Cannabinoid subtype-2 receptors modulate the antihyperalgesic effect of WIN 55,212-2 in rats with neuropathic spinal cord injury pain. (abst 2010)
Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain. (full 2010)
Cannabinoid inhibition of macrophage migration to the trans-activating (Tat) protein of HIV-1 is linked to the CB(2) cannabinoid receptor. (full 2010)
Consider the CB(2) Receptor
(article 2010)
http://www.wellsphere.com/drug-addiction-article/consider-the-cb-2-receptor/1164631
Paradoxical effects of the cannabinoid CB2 receptor agonist GW405833 on rat osteoarthritic knee joint pain. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20863899 The development of cannabinoid CBII receptor agonists for the treatment of central neuropathies. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20236042/abstract/The_development_of_cannabin oid_CBII_receptor_agonists_for_the_treatment_of_central_neuropathies_

(abst 2010)
Interaction between anandamide and sphingosine-1-phosphate in mediating vasorelaxation in rat coronary artery (abst 2010)
Studies demonstrate analgesic properties of synthetic cannabinoid
(news 2010)
http://www.news-medical.net/news/20100702/Studies-demonstrate-analgesic-properties-of-syntheticcannabinoid.aspx
Deletion of CB2 Cannabinoid Receptor Induces Schizophrenia-Related Behaviors in Mice (full 2011) http://www.nature.com/npp/journal/v36/n7/full/npp201134a.html Cannabinoid receptor 2 signaling does not modulate atherogenesis in mice (full 2011)
Cannabinoid Receptor 2 Deficiency in Haematopoietic cells Aggravates Early Atherosclerosis in LDL Receptor Deficient Mice. (full 2011)
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WIN55,212-2 induces cytoplasmic vacuolation in apoptosis-resistant MCL cells. (full 2011) http://www.nature.com/cddis/journal/v2/n11/full/cddis2011106a.html Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines. (full 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930808/?tool=pubmed New blood brothers: the GPR55 and CB2 partnership
http://www.nature.com/cr/journal/vaop/ncurrent/full/cr201177a.html
(full 2011)
Functional selectivity in CB2 cannabinoid receptor signaling and regulation: implications for the therapeutic potential of CB2 ligands. (full 2011)

Regulatory effect of cannabinoid receptor agonist on chemokine-induced lymphocyte chemotaxis. (full 2011) http://www.jstage.jst.go.jp/article/bpb/34/7/1090/_pdf Cannabinoid receptor 2 positions and retains marginal zone B cells within the splenic marginal zone. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21875957 Cannabidiol decreases body weight gain in rats: Involvement of CB2 receptors. (abst - 2011) http://marijuana.researchtoday.net/archive/8/1/3517.htm The role of central CB2 cannabinoid receptors on food intake in neonatal chicks. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21927979 Self-medication of a cannabinoid CB(2) agonist in an animal model of neuropathic pain. (abst 2011)
Protective Role of Cannabinoid Receptor Type 2 in a Mouse Model of Diabetic Nephropathy. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21810593
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The Type 2 Cannabinoid Receptor Regulates Bone Mass and Ovariectomy-Induced Bone Loss by Affecting Osteoblast Differentiation and Bone Formation (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21447627/abstract/The_Type_2_Cannabinoid_Rec eptor_Regulates_Bone_Mass_and_Ovariectomy_Induced_Bone_Loss_by_Affecting_Osteoblast_Differenti ation_and_Bone_Formation_
GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils. (abst 2011)

Cannabinoid receptor 2 and its agonists mediate hematopoiesis and hematopoietic stem and progenitor cell mobilization. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21063029 Deletion of cannabinoid receptors 1 and 2 exacerbates APC function to increase inflammation and cellular immunity during influenza infection. (abst 2011)
Win 55,212-2 reduces cardiac ischaemia-reperfusion injury in zucker diabetic fatty rats: role of cb2 receptors and cardiac inos/enos expression. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21309057/abstract/Win_55212_2_reduces_cardiac _ischaemia_reperfusion_injury_in_zucker_diabetic_fatty_rats:_role_of_cb2_receptors_and_cardiac_inos/e nos_expression_
CNS effects of CB2 cannabinoid receptors: beyond neuro-immuno-cannabinoid activity (abst 2011)
http://jop.sagepub.com/content/early/2011/03/29/0269881111400652.abstract?maxtoshow=&hits=80&RES ULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=160&sortspec=date&resourcetype=H WCIT
Overexpression of CB2 cannabinoid receptors results in neuroprotection against behavioral and neurochemical alterations induced by intracaudate administration of 6hydroxydopamine. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/20980074 Genetic association between bipolar disorder and 524A>C (Leu133Ile) polymorphism of CNR2 gene, encoding for CB2 cannabinoid receptor. (abst - 2011)
Is lipid signaling through cannabinoid 2 receptors part of a protective system? (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21295074 Brain cannabinoid CB2 receptors modulate cocaine's actions in mice
http://www.nature.com/neuro/journal/vaop/ncurrent/full/nn.2874.html
(abst 2011)
G-protein coupled receptors regulating cough.

(abst 2011)
Commentary: Functional Neuronal CB2 Cannabinoid Receptors in the CNS. (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137183/?tool=pubmed
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Atheroprotection via cannabinoid receptor-2 is mediated by circulating and vascular cells in vivo. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21884703 Design and evaluation of a novel fluorescent CB2 ligand as probe for receptor visualization in immune cells. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21855337 Deletion of CB2 cannabinoid receptor induces schizophrenia-related behaviors in mice. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21430651 Endocannabinoid system and psychiatry: in search of a neurobiological basis for detrimental and potential therapeutic effects. (abst 2011)
Regulation of hematopoietic stem cell trafficking and mobilization by the endocannabinoid system. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22074629 Cannabinoid receptor 2 and its agonists mediate hematopoiesis and hematopoietic stem and progenitor cell mobilization. (abst 2011)
Antinociceptive effects induced through the stimulation of spinal cannabinoid type 2 receptors in chronically inflamed mice (abst - 2011)
Spinal cannabinoid CB2 receptors as a target for neuropathic pain: an investigation using chronic constriction injury. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22210507 Beneficial paracrine effects of cannabinoid receptor 2 on liver injury and regeneration. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/20597071/abstract/Beneficial_paracrine_effects_of _cannabinoid_receptor_2_on_liver_injury_and_regeneration_
Cannabinoid receptor-2 (CB2) agonist ameliorates colitis in IL-10(-/-) mice by attenuating the activation of T cells and promoting their apoptosis. (abst 2011)
CB2 Cannabinoid Receptors Promote Neural Progenitor Cell Proliferation via mTORC1 Signaling (abst 2011)
Behavioral effects of pulp exposure in mice lacking cannabinoid receptor 2. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/22152627 Cannabinoid type 2 receptor activation downregulates stroke-induced classic and alternative brain macrophage/microglial activation concomitant to neuroprotection. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/22020035
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Cannabinoid CB(2) receptor-mediated regulation of impulsive-like behaviour in DBA/2 mice. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/21671903 Overexpression of CB2 cannabinoid receptors results in neuroprotection against behavioral and neurochemical alterations induced by intracaudate administration of 6hydroxydopamine. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/20980074
CBR GPR-40 CANNABINOID RECEPTOR - activated by GW1100, TAK-875 The Ffa Receptor Gpr40 Links Hyperinsulinemia, Hepatic Steatosis, and Impaired Glucose Homeostasis in Mouse. (abst 2005)
http://medical-journals.healia.com/doc/16054069/The-FFA-receptor-GPR40-links-hyperinsulinemiahepatic-steatosis-and-impaired-glucose-homeostasis-in-mouse
Gpr40 Gene Expression in Human Pancreas and Insulinoma.
(abst 2005)
http://medical-journals.healia.com/doc/16289108/GPR40-gene-expression-in-human-pancreas-andinsulinoma
Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules. (full - 2006)
Expression of the Gene for a Membrane-bound Fatty Acid Receptor in the Pancreas and Islet Cell Tumours in Humans: Evidence for Gpr40 Expression in Pancreatic Beta Cells and Implications for Insulin Secretion. (abst 2006)
http://medical-journals.healia.com/doc/16525841/Expression-of-the-gene-for-a-membrane-bound-fattyacid-receptor-in-the-pancreas-and-islet-cell-tumours-in-humans-evidence-for-GPR40-expression-inpancreatic-beta-cells-and-implications-for-insulin-secretion
Selective small-molecule agonists of G protein-coupled receptor 40 promote glucosedependent insulin secretion and reduce blood glucose in mice. (full 2008)
Overexpression of GPR40 in pancreatic beta-cells augments glucose-stimulated insulin secretion and improves glucose tolerance in normal and diabetic mice. (full 2009)
Acute administration of GPR40 receptor agonist potentiates glucose-stimulated insulin secretion in vivo in the rat. (abst 2009) http://www.ncbi.nlm.nih.gov/pubmed/19217448 Takeda moves potential first-in-class diabetes drug into phase III
http://www.inpharm.com/news/166980/takeda-diabetes-tak-875-phase-iii
(news 2011)
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CBR - GPR55/ CB3 CANNABINOID RECEPTOR

Activated by THC, CBD,O-1602, PEA, 2-AG, Anandamide
Cannabinoid Receptor Ligands
(full - no date)
Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain. (abst - 1999) http://www.ncbi.nlm.nih.gov/pubmed/9931487 Evolutionary Origins of the Endocannabinoid System. GPR55: a new member of the cannabinoid receptor clan?
(abst 2006) (full - 2007)
The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects. (full - 2007)
GPR55 and the vascular receptors for cannabinoids. GPR55 is a novel cannabinoid receptor Novel cannabinoid receptors
(full - 2007)
(full - 2007) (needs registration)
http://www.biomedcentral.com/1471-2210/7/S2/A3
(full - 2007) (abst - 2007) (needs registration)
GPR55: signaling pathways and functions

http://www.biomedcentral.com/1471-2210/9/S2/A3
GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268199/?tool=pubmed The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737440/?tool=pubmed Receptors for acylethanolamides-GPR55 and GPR119. Is GPR55 an anandamide receptor? (abst - 2009) (abst - 2009) (full 2009)
The enigmatic pharmacology of GPR55.

http://www.ncbi.nlm.nih.gov/pubmed/19233486.
219
Atypical responsiveness of the orphan receptor GPR55 to cannabinoid ligands. (full - 2009)
http://www.jbc.org/content/284/43/29817.full?sid=ec54c280-2526-4d1b-ab9f-73a1ca683a5e
Pharmacological characterization of GPR55, a putative cannabinoid receptor. (abst 2010)

http://www.unboundmedicine.com/medline/ebm/record/20298715/abstract/Pharmacological_characterizati on_of_GPR55_a_putative_cannabinoid_receptor_
The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/21080464 GPR55: Current Knowledge and Future Perspectives of a Purported "Type-3" Cannabinoid Receptor. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20166924 Cannabinoids and the gut: new developments and emerging concepts
(abst - 2010)
A role for L-alpha-lysophosphatidylinositol and GPR55 in the modulation of migration, orientation and polarization of human breast cancer cells. (abst - 2010)
Cannabinoids and Bone: Friend or Foe?

(abst - 2010)
Endocannabinoid-like N-arachidonoyl serine is a novel pro-angiogenic mediator. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20649563 Screening for Selective Ligands for GPR55.
http://www.ncbi.nlm.nih.gov/books/NBK66153/
(full 2011) (full 2011)
New blood brothers: the GPR55 and CB2 partnership

What is the natural ligand of GPR55?
(abst 2011)
http://jb.oxfordjournals.org/content/149/5/495.short?rss=1
Pharmacology, Signaling and Physiological Relevance of the G Protein-coupled Receptor 55. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21907912 GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils. (abst 2011)
The GPCR - associated sorting protein 1 regulates ligand-induced downregulation of GPR55. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21718301
220
Anandamide exerts its antiproliferative actions on cholangiocarcinoma by activation of the GPR55 receptor. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21464819 The novel cannabinoid receptor GPR55, inhibits cholangiocarcinoma growth (abst 2011)
http://www.fasebj.org/cgi/content/meeting_abstract/25/1_MeetingAbstracts/1117.3?maxtoshow=&hits=80 &RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcety pe=HWCIT
Modulation of the novel cannabinoid receptor - GPR55 - during rat fetoplacental development (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21497900 A novel CB receptor GPR55 and its ligands are involved in regulation of gut movement in rodents. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21726355 The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21744421 The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55. (abst 2011)
A role for the putative cannabinoid receptor GPR55 in the islets of Langerhans. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21885477 Pharmacology, signaling and physiological relevance of the G protein-coupled receptor 55. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21907912 Functional polymorphism in the GPR55 gene is associated with anorexia nervosa. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/20506567 The putative cannabinoid receptor GPR55 defines a novel autocrine loop in cancer cell proliferation. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/20838378
CBR - GPR109 CANNABINOID RECEPTOR Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells (full 2011)
http://www.jci.org/articles/view/41651?search[abstract_text]=&search[article_text]=cannabinoid&search[a uthors_text]=&search[fpage]=&search[issue]=&search[title_text]=&search[volume
221
CBR - GPR119 CANNABINOID RECEPTOR - activated by PEA, OEA A role for beta-cell-expressed G protein-coupled receptor 119 in glycemic control by enhancing glucose-dependent insulin release. (full 2007)
http://endo.endojournals.org/content/148/6/2601.long
GPR119, a novel G protein-coupled receptor target for the treatment of type 2 diabetes and obesity (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268073/?tool=pmcentrez Receptors for acylethanolamides-GPR55 and GPR119.
(full 2009)
N-oleoyldopamine enhances glucose homeostasis through the activation of GPR119. (full 2010) http://mend.endojournals.org/content/24/1/161.long GPR119 agonists for the potential treatment of type 2 diabetes and related metabolic disorders. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/21094910 Novel GPR119 agonist AS1535907 contributes to first-phase insulin secretion in rat perfused pancreas and diabetic db/db mice. (abst 2010)
AS1907417, a novel GPR119 agonist, as an insulinotropic and -cell preservative agent for the treatment of type 2 diabetes. (abst 2010)
GPR119 Regulates Murine Glucose Homeostasis Through Incretin Receptor-Dependent and Independent Mechanisms (abst 2011)
http://endo.endojournals.org/content/152/2/374.abstract?sid=c77be354-b90f-4368-9bb3-fea533824b24
The cytoprotective effects of oleoylethanolamide in insulin-secreting cells do not require activation of GPR119. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22029844
CELIAC DISEASE Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-treated rats. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17396241 Hemp: A replacement for common food allergens? (news - 2009)
222
Celiac Disease and Medical Marijuana

http://pharmcannabis.com/?p=14
(news 2009) (abst 2011)
Abnormal anandamide metabolism in celiac disease.

CEREBRAL PALSY Treatment of human spasticity with delta 9-tetrahydrocannabinol.

(abst 1981)
Endocannabinoids potently protect the newborn brain against AMPA-kainate receptormediated excitotoxic damage. (full 2006)
Marijuana: an effective antiepileptic treatment in partial epilepsy? A case report and eview of the literature. (abst 2007)
http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=157&
CESAMET - see NABILONE
CHEMICAL COMPOSITION Compounds found in Cannabis Sativa (list- no date) (full - 1938)
http://www.ukcia.org/research/cannabis-compounds.htm
The active principles of Cannabis indica resin. I.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1264344/pdf/biochemj01029-0136.pdf
The Active Principles of Cannabis and the Pharmacology of the Cannabinols (full - 1940) http://www.ukcia.org/research/TherapeuticPotentialMedicalUses.php HEMP AS A MEDICAMENT : Properties of isolated substances
http://www.greenpassion.org/showthread.php?p=306831#post306831
(full - 1955) (full - 1955)
HEMP AS A MEDICAMENT : Survey of clinical experiences

Recent Developments in Cannabis Chemistry

http://www.onlinepot.org/medical/Dr_Tods_PDFs/s5_6.pdf
(full - 1972)
223
A SIMPLE METHOD FOR DEMONSTRATING TETRAHYDROCANNABINOLS IN FRESH OR FIXED FROZEN SECTIONS (full 1972)
http://jhc.sagepub.com/content/20/10/827.full.pdf+html
Water-soluble derivatives of 1 -tetrahydrocannabinol.

(abst - 1972)
The chemistry and biological activity of cannabis Cannabinoid Phenotypes in Cannabis sativa
(news - 1972)
http://www.unodc.org/unodc/en/data-and-analysis/bulletin/bulletin_1972-01-01_2_page005.html
(abst - 1973)
http://www.nature.com/nature/journal/v245/n5421/abs/245147a0.html
Constituents of Cannabis sativa L. II: Absence of cannabidiol in an african variant (abst 1975) http://onlinelibrary.wiley.com/doi/10.1002/jps.2600620214/abstract Constituents of Cannabis sativa L. VIII: Possible biological application of a new method to separate cannabidiol and cannabichromene. (abst - 1975)
Cannabinoid Profile and Elemental Uptake of Cannabis sativa L. as Influenced by Soil Characteristics (abst - 1975)
http://agron.scijournals.org/cgi/content/abstract/67/4/491?maxtoshow=&hits=80&RESULTFORMAT=&fu lltext=marihuana&searchid=1&FIRSTINDEX=240&resourcetype=HWCIT
Ganja in Jamaica : Appendix III Laboratory Analyses of Ganja Samples. (book 1976) http://www.cifas.us/cannabis/PDFs/OCRGanjainJamaica.pdf Cannabinoid patterns in seedlings of Cannabis sativa L. and their use in the determination of chemical race. (abst 1977) http://www.ncbi.nlm.nih.gov/pubmed/19599 Cannabinoid formation in Cannabis sativa grafted inter-racially, and with two Humulus species (abst - 1975)
https://www.unodc.org/unodc/en/data-and-analysis/bulletin/bulletin_1978-01-01_1_page007.html
Responses of Greenhouse-grown Cannabis sativa L. to Nitrogen, Phosphorus, and Potassium (abst - 1977)
http://agron.scijournals.org/cgi/content/abstract/69/5/832?maxtoshow=&hits=80&RESULTFORMAT=&fu lltext=marihuana&searchid=1&FIRSTINDEX=320&resourcetype=HWCIT
The decomposition of acidic and neutral cannabinoids in organic solvents.

(abst 1977)
CHEMOTAXONOMY OF CANNABIS 1. CROSSBREEDING BETWEEN CANNABIS SATIVA AND C. RUDERALIS, WITH ANALYSIS OF CANNABINOID CONTENT (full - 1978)
http://www.cannabase.com/cl/bcga/journals/Beutler1979/Beutler1979.html
224
Influence of photoperiodism on cannabinoid content of Cannabis sativa L. (abst 1978)

An investigation of procedures reported to increase potency of marijuana: a chemical analysis and psychological interpretation. (abst 1978)
Interrelationships of glandular trichomes and cannabinoid content. I: Developing pistillate bracts of Cannabis sativa L. (Cannabaceae). (full 1981)
http://www.unodc.org/unodc/en/data-and-analysis/bulletin/bulletin_1981-01-01_3_page007.html
Interrelationships of glandular trichomes and cannabinoid content II. Developing vegetative leaves of Cannabis sativa L. (Cannabaceae) (full - 1981)
http://www.cannabase.com/cl/bcga/journals/Turner1981b/turner1981b.html
Chemataxonomic researches in higher plants. XV Carotenoid and chlorophyll pigments in the leaves of Cannabis sativa L. (full - 1981)
http://notulaebotanicae.ro/nbha/article/view/144/138
Constituents of Cannabis sativa L., XX: the cannabinoid content of Mexican variants grown in Mexico and in Mississippi, United States of America (full - 1982)
http://www.cannabase.com/cl/bcga/journals/Turner1982a/turner1982a.html
Constituents of Cannabis sativa, XXV. Isolation of two new dihydrostilbenes from a Panamanian variant. (abst 1984) http://www.ncbi.nlm.nih.gov/pubmed/6481358 Cannabinoid content of cannabis grown on the Danish island of Bornholm. (abst 1985) http://www.ncbi.nlm.nih.gov/pubmed/3011164 Identification of a New Chemotype in Cannabis sativa: Cannabigerol - Dominant Plants, Biogenetic and Agronomic Prospects (abst 1987)
Oral vs. Inhaled Cannabinoids for Nausea/Vomiting from Cancer Chemotherapy (full - 1988) http://www.medmjscience.org/Pages/science/pierson.html Histochemical detection of hemp trichomes and their correlation with the THC content. (abst - 1988)
Characterization of the lipophilicity of natural and synthetic analogs of delta 9tetrahydrocannabinol and its relationship to pharmacological potency. (abst - 1990)
Cannabinoid acids analysis. (abst 1992)
225
Some features of Cannabis plants grown in the United Kingdom from seeds of known origin. (abst - 1992) http://www.unboundmedicine.com/medline/ebm/record/1361557/abstract/ Chemical ecology of Cannabis (full - 1994)
http://www.hempfood.com/Iha/iha01201.html
The Volatile Oil Composition of Fresh and Air-Dried Buds of Cannabis sativa (full 1996) http://www.cannabis-science.com/papers/oil%20comp%20cannabis.pdf Effect of nitrogen on tetrahydrocannabinol (THC) content in hemp (Cannabis sativa L.) leaves at different positions (full - 1997)
http://www.internationalhempassociation.org/jiha/jiha4207.html
Essential Oil of Cannabis sativa L. Strains
(full 1997)
http://www.cannabis-science.com/papers/essentialoilcsativa.html
Capillary electrochromatography of cannabinoids. (abst 1998)

Medical Cannabis Potency Testing Project

http://www.maps.org/news-letters/v09n3/09320gie.html
(full - 1999) (news - 1999)
Hemp Seed Oil : The Wonder Oil For the New Millennium
http://www.ukcia.org/research/Happi/HempSeedOilTheWonderOilForTheNewMillennium.htm
Development of a novel class of monocyclic and bicyclic alkyl amides that exhibit CB1 and CB2 cannabinoid receptor affinity and receptor activation. (abst 2000)
Characterisation of cannabis plants phenotypes from illegal cultivations in Crete (abst - 2000)
http://www.ncbi.nlm.nih.gov/pubmed/10961025?ordinalpos=89&itool=EntrezSystem2.PEntrez.Pubmed.Pu bmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
GC-MS analysis of the total delta9-THC content of both drug- and fiber-type cannabis seeds. (abst 2000) http://www.ncbi.nlm.nih.gov/pubmed/11110027 Differential effects of medical marijuana based on strain and route of administration : A three-year observational study (full - 2001)
http://www.ukcia.org/research/DifferentialEffects/
Cannabis and Cannabis Extracts: Greater Than the Sum of Their Parts? (full - 2001)
http://www.cannabis-med.org/membersonly/mo.php?aid=2001-03-04&fid=2001-03-04-7&mode=p&sid=
226
The inheritance of chemical phenotype in Cannabis sativa L.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462421/pdf/12586720.pdf
(full - 2002) (full - 2002)
Cannabis / Marijuana ( 9 -Tetrahydrocannabinol, THC)
http://www.nhtsa.dot.gov/people/injury/research/job185drugs/cannabis.htm
Biochemical differences in Cannabis sativa L. depending on sexual phenotype (full - 2002) http://jag.igr.poznan.pl/2002-Volume-43/4/pdf/2002_Volume_43_4-451-462.pdf Chemotaxonomic features associated with flavonoids of cannabinoid-free cannabis (Cannabis sativa subsp. sativa L.) in relation to hops (Humulus lupulus L.). (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/11942684 Composition of the essential oils and extracts of two populations of Cannabis sativa L. ssp. spontanea from Austria (full - 2003)
http://findarticles.com/p/articles/mi_qa4091/is_/ai_n9299539
Cannabis: A source of useful pharma compounds neglected in India

http://www.medpot.net/forums/index.php?showtopic=18608
(news - 2003)
A chemotaxonomic analysis of cannabinoid variation in Cannabis (Cannabaceae) (full - 2004) http://www.amjbot.org/cgi/content/full/91/6/966 The gene controlling marijuana psychoactivity: molecular cloning and heterologous expression of Delta1-tetrahydrocannabinolic acid synthase from Cannabis sativa L. (full 2004) http://www.jbc.org/content/279/38/39767.long Comparative Proteomics of Cannabis sativa Plant Tissues (full - 2004)
(+)-Cannabidiol analogues which bind cannabinoid receptors but exert peripheral activity only. (abst 2004) http://www.ncbi.nlm.nih.gov/pubmed/15588739 NMR assignments of the major cannabinoids and cannabiflavonoids isolated from flowers of Cannabis sativa (abst - 2004)
Hemp-seed and olive oils: their stability against oxidation and use in O/W emulsions. (abst 2004) http://www.ncbi.nlm.nih.gov/pubmed/16130045 Plant cannabinoids: a neglected pharmacological treasure trove (full - 2005)
Flavonoid glycosides and cannabinoids from the pollen of Cannabis sativa L. (abst - 2005)
227
Cultivation of Cannabis sativa L. in northern Morocco.

(abst 2005)
Chemical constituents of marijuana: the complex mixture of natural cannabinoids. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/16199061 Tetrahydrocannabinolic acid synthase, the enzyme controlling marijuana psychoactivity, is secreted into the storage cavity of the glandular trichomes. (abst 2005)
Pharmacokinetics and cannabinoid action using oral cannabis extract

http://www.pharma-lexicon.com/medicalnews.php?newsid=29638
(news - 2005)
Cannabis confusions
(full - 2006)
Evaluation of herbal cannabis characteristics by medical users: a randomized trial (full - 2006) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1654142&tool=pmcentrez Alpha-linolenic acid content of commonly available nuts in Hangzhou.
(abst 2006)
DNA poly morphisms in the tetrahydrocannabinolic acid (THCA) synthase gene in "drug-type" and "fiber-type" Cannabis sativa L. (abst 2006)
Analysis of Choline and Atropine in Hairy Root Cultures of Cannabis Sativa L. by Capillary Electrophoresis-electrospray Mass Spectrometry. (abst 2006)
http://medical-journals.healia.com/doc/16637019/Analysis-of-choline-and-atropine-in-hairy-root-culturesof-Cannabis-sativa-L.-by-capillary-electrophoresis-electrospray-mass-spectrometry
Identification and Characterization of Cannabinoids That Induce Cell Death through Mitochondrial Permeability Transition in Cannabis Leaf Cells (full 2007)
http://www.jbc.org/content/282/28/20739.full?sid=a5db98db-ff96-4187-8790-57097bbe15c1
Cannabidiolic-acid synthase, the chemotype-determining enzyme in the fiber-type Cannabis sativa. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17544411 Phytochemical and genetic analyses of ancient cannabis from Central Asia (full - 2008)
Characterization of Medicinal Properties of Cannabis sativa L. Roots
(full - 2008)
http://archives.hempembassy.net/hempe/resources/blairvanpeltcannabisroot%20_NXPowerLite_.pdf
Non-cannabinoid constituents from a high potency Cannabis sativa variety. (abst - 2008)
http://www.unboundmedicine.com/medline/ebm/record/18774146/abstract/Non_cannabinoid_constituents_ from_a_high_potency_Cannabis_sativa_variety_
228
Cannabinoid Ester Constituents from High-Potency Cannabis sativa.
(abst - 2008)
http://www.unboundmedicine.com/medline/ebm/record/18303850/abstract/Cannabinoid_Ester_Constituent s_from_High_Potency_Cannabis_sativa_
Identification of candidate genes affecting 9-tetrahydrocannabinol biosynthesis in Cannabis sativa (full - 2009)
2.0 Clinical Pharmacology
(full - 2009)
http://www.hc-sc.gc.ca/dhp-mps/marihuana/how-comment/medpract/infoprof/clinical-clinique-eng.php
Hydroxylation and Further Oxidation of 9-Tetrahydrocannabinol by Alkane-Degrading Bacteria (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786519/?tool=pmcentrez US Patent Application 20090324797 - MODULATING PLANT OIL LEVELS (full 2009) http://www.patentstorm.us/applications/20090324797/fulltext.html Effects of Gibberellic Acid on Primary Terpenoids and Delta-Tetrahydrocannabinol in Cannabis sativa at Flowering Stage. ( abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19522814/abstract/Effects_of_Gibberellic_Acid_o n_Primary_Terpenoids_and_Delta_Tetrahydrocannabinol_in_Cannabis_sativa_at_Flowering_Stage_
A qualitative and quantitative HPTLC densitometry method for the analysis of cannabinoids in Cannabis sativa L. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19609880/abstract/A_qualitative_and_quantitative _HPTLC_densitometry_method_for_the_analysis_of_cannabinoids_in_Cannabis_sativa_L_
Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoids in cannabis plant material (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19932642 9-Tetrahydrocannabinol content in cannabis samples seized in Novi Sad during 2008 (full 2010) http://www.shd.org.rs/JSCS/Vol75/No7/02_4595_4015.pdf In silicio expression analysis of PKS genes isolated from Cannabis sativa L. (full 2010)
Metabolic fingerprinting of Cannabis sativa L., cannabinoids and terpenoids for chemotaxonomic and drug standardization purposes. (abst 2010)
The Terpenes in the Cannabis Plant How Accurate is Potency Testing?
(news - 2010) (full 2011)
http://cannabination.com/2010/09/30/the-terpenes-in-the-cannabis-plant/
http://www.canorml.org/RingTestOShaughnessys_Aut11.pdf
Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21749363
229
Heterogeneity in the composition of marijuana seized in California.
(abst 2011)
Characteristics of cannabinoids composition of Cannabis plants grown in Northern Thailand and its forensic application. (abst 2011)
Sub-chronic impact of cannabinoids in street cannabis on cognition, psychotic-like symptoms and psychological well-being. (abst 2011)
Bioactive Prenylogous Cannabinoid from Fiber Hemp (Cannabis sativa).

(abst -2011)
Cadmium Tolerance and Bioaccumulation of 18 Hemp Accessions.

(abst 2011)
Cannabinoids: occurrence and medicinal chemistry.
(abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21254969/abstract/Cannabinoids:_occurrence_and _medicinal_chemistry_
The cannabinoid type-1 receptor carboxyl-terminus, more than just a tail.
(abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21244428/abstract/The_cannabinoid_type_1_recep tor_carboxyl_terminus_more_than_just_a_tail_
Cannabis profiling based on its elemental composition--is it possible?

(abst 2011)
The Effect of Electrical Lighting Power and Irradiance on Indoor-Grown Cannabis Potency and Yield. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22211717 A real-time PCR assay for the relative quantification of the tetrahydrocannabinolic acid (THCA) synthase gene in herbal Cannabis samples (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/22093702/abstract/A_real_time_PCR_assay_for_t he_relative_quantification_of_the_tetrahydrocannabinolic_acid__THCA__synthase_gene_in_herbal_Cann abis_samples_
Cannabis Sequencing Study Explores Differences Between Marijuana, Hemp Producing Plants (news 2011)
http://www.genomeweb.com/sequencing/cannabis-sequencing-study-explores-differences-betweenmarijuana-hemp-producing
10 Questions To Ask Your Cannabis Scientist Chocolate & marijuana: chemical cousins
(news- 2011)
http://www.freedomisgreen.com/10-questions-to-ask-your-cannabis-scientist/
(news 2011)
http://www.examiner.com/drug-policy-in-reno/chocolate-marijuana-chemical-cousins
230
Proteomic profiling of hempseed proteins from Cheungsam.

(abst - 2012)
CHEMOTHERAPY Antiemetic effect of delta-9-tetrahydrocannabinol in patients receiving cancer chemotherapy. (abst - 1975)
Delta-9-tetrahydrocannabinol as an antiemetic in cancer patients receiving high-dose methotrexate. A prospective, randomized evaluation. (abst - 1979)
Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9tetrahydrocannabinol. (abst - 1979)

Antiemetics in patients receiving chemotherapy for cancer: a randomized comparison of delta-9-tetrahydrocannabinol and prochlorperazine. (abst - 1980)
Antiemetic effect of tetrahydrocannabinol. Compared with placebo and prochlorperazine in chemotherapy-associated nausea and emesis. (abst - 1980)
Double-blind comparison of the antiemetic effects of nabilone and prochlorperazine on chemotherapy-induced emesis. (abst - 1980)
231
Physiologic observations in a controlled clinical trial of the antiemetic effectiveness of 5, 10, and 15 mg of delta 9-tetrahydrocannabinol in cancer chemotherapy. Ophthalmologic implications. (abst - 1981)
Clinical experience with levonantradol hydrochloride in the prevention of cancer chemotherapy-induced nausea and vomiting. (abst 1981)
Dose vs response of tetrahydroannabinol (THC) vs prochlorperazine as chemotherapy antiemetics. (abst - 1981)

Comparative trial of the antiemetic effects of THC and haloperidol

(abst - 1981)
Levonantradol, a new antiemetic with a high rate of side-effects for the prevention of nausea and vomiting in patients receiving cancer chemotherapy. (abst 1982)
Cannabis and cancer chemotherapy: a comparison of oral delta-9-THC and prochlorperazine. (abst 1982) http://www.ncbi.nlm.nih.gov/pubmed/6284334 A double-blind, controlled trial of nabilone vs. prochlorperazine for refractory emesis induced by cancer chemotherapy. (abst - 1982)
Anti-emetic efficacy and toxicity of nabilone, a synthetic cannabinoid, in lung cancer chemotherapy. (full - 1983)
Levonantradol: a synthetic cannabinoid in the treatment of severe chemotherapy-induced nausea and vomiting resistant to conventional anti-emetic therapy. (abst 1983)
Antiemetic efficacy of levonantradol compared to delta-9-tetrahydrocannabinol for chemotherapy-induced nausea and vomiting. (abst 1985)
THC or Compazine for the cancer chemotherapy patient--the UCLA study. Part II: Patient drug preference. (abst - 1985)
232
A cross-over comparison of nabilone and prochlorperazine for emesis induced by cancer chemotherapy. (abst - 1985)
Nabilone: an alternative antiemetic for cancer chemotherapy.

(full - 1986)
Crossover comparison of the antiemetic efficacy of nabilone and alizapride in patients with nonseminomatous testicular cancer receiving cisplatin therapy (abst - 1986)
Prospective randomized double-blind trial of nabilone versus domperidone in the treatment of cytotoxic-induced emesis. (abst - 1986)
Nabilone versus prochlorperazine for control of cancer chemotherapy-induced emesis in children: a double-blind, crossover trial. (abst - 1987)
Efficacy of tetrahydrocannabinol in patients refractory to standard anti-emetic therapy (abst - 1988) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=31 A randomized trial of oral nabilone and prochlorperazine compared to intravenous metoclopramide and dexamethasone in the treatment of nausea and vomiting induced by chemotherapy regimens containing cisplatin or cisplatin analogues. (abst 1988)
Peer Reviewed Results of New York State-sponsored Cancer/Marijuana Studies (abst - 1988) http://www.medmjscience.org/Pages/science/vinciguerra.html Marijuana as antiemetic medicine : A Survey of Oncologists' Experiences and Attitudes (full - 1991) http://www.maps.org/docs/doblin-mt.html Dronabinol and prochlorperazine in combination for treatment of cancer chemotherapyinduced nausea and vomiting. (abst - 1991) http://www.ncbi.nlm.nih.gov/pubmed/1652611 An efficient new cannabinoid antiemetic in pediatric oncology
http://www.druglibrary.org/olsen/hemp/iha/iha02210.html
(full - 1995)

(full - 2001)
Cannabinoids for control of chemotherapy induced nausea and vomiting: quantitative systematic review (full - 2001)
233
http://findarticles.com/p/articles/mi_m0999/is_7303_323/ai_n27569247/?tag=content;col1
Cannabinoids for control of chemotherapy induced nausea and vomiting: quantitative systematic review (abst - 2001)
http://www.bmj.com/cgi/content/abstract/323/7303/16?ijkey=4c757e94f7e19cc6a3f945402c7dd6eb0fe3f04 e&keytype2=tf_ipsecsha
The cannabinoids: an overview. Therapeutic implications in vomiting and nausea after cancer chemotherapy, in appetite promotion, in multiple sclerosis and in neuroprotection. (abst - 2001) http://www.ncbi.nlm.nih.gov/pubmed/11854768?dopt=Abstract Different views on the association between cannabinoids and cancer (abst - 2006)
Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases (abst - 2006) http://lib.bioinfo.pl/pmid:16408219 Activation of cannabinoid CB1 and CB2 receptors suppresses neuropathic nociception evoked by the chemotherapeutic agent vincristine in rats. (full 2007)
Cannabinoids in the treatment of chemotherapy-induced nausea and vomiting: beyond prevention of acute emesis. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17566383 Efficacy of dronabinol alone and in combination with ondansetron versus ondansetron alone for delayed chemotherapy-induced nausea and vomiting. (abst - 2007)
Pot Compound May Offer Non-Toxic Alternative To Chemotherapy

(news 2007)
Pharmacological Inhibition of CB1 Cannabinoid Receptor Protects Against DoxorubicinInduced Cardiotoxicity (full - 2008) http://content.onlinejacc.org/cgi/content/full/50/6/528 Oral nabilone capsules in the treatment of chemotherapy-induced nausea and vomiting and pain. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18095921 Efficacy of Crude Marijuana and Synthetic Delta-9-Tetrahydrocannabinol as Treatment for Chemotherapy-Induced Nausea and Vomiting: A Systematic Literature Review. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19596652/abstract/Efficacy_of_Crude_Marijuana_ and_Synthetic_Delta_9_Tetrahydrocannabinol_as_Treatment_for_Chemotherapy_Induced_Nausea_and_V omiting:_A_Systematic_Literature_Review_
234
Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines. (abst 2009) http://www.ncbi.nlm.nih.gov/pubmed/19394652 Cannabinoid-2 receptor limits inflammation, oxidative/nitrosative stress, and cell death in nephropathy. (full 2010)
Mechanisms of Broad-Spectrum Antiemetic Efficacy of Cannabinoids against Chemotherapy-Induced Acute and Delayed Vomiting (full 2010)
Preliminary efficacy and safety of an oromucosal standardized cannabis extract in chemotherapy-induced nausea and vomiting (full - 2010)
http://www.unboundmedicine.com/medline/ebm/record/21039759/abstract/Preliminary_efficacy_and_safet y_of_an_oromucosal_standardized_cannabis_extract_in_chemotherapy_induced_nausea_and_vomiting_
(abst - 2010)
Marijuana Extract Might Help Prevent Chemotherapy-Related Nerve Pain (news 2011) http://www.newswise.com/articles/view/580864/?sc=rsmn Cannabinoid 'Completely' Prevents Chemotherapy-Induced Neuropathy, Study Says (news 2011) http://www.norml.org/index.cfm?Group_ID=8710 Marijuana component may ease pain from chemo therapy drugs
(news 2011)
(news 2011) (anecdotal 2011)
Father: Medical marijuana eased pain of my cancer-battling son

235
CHILDREN/ YOUNG ADULTS Hemp Packs in Powerful Source of Preconception Nutrition (article - no date)
http://manitobaharvest.com/articles_studies/3812/Hemp-Packs-in-Powerful-Source-of-PreconceptionNutrition.html
HEMP AS A MEDICAMENT : Importance of hemp seeds in the tuberculosis therapy (Forum thread- full- 1955) (EDEZYME. recipe)
Survey of adolescent drug use. I. Sex and grade distribution. Adolescent Marihuana Use: Role of Parents and Peers.
(full 1971)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1530048/pdf/amjph00747-0113.pdf
(abst 1976) (abst - 1986)
http://medical-journals.healia.com/doc/4726001/Adolescent-marihuana-use-role-of-parents-and-peers

Nabilone versus prochlorperazine for control of cancer chemotherapy-induced emesis in children (abst - 1987)
Marijuana Use in Pregnancy and Pregnancy Outcome.

(abst 1990)
Five-year follow-up of rural Jamaican children whose mothers used marijuana during pregnancy. (abst 1991) http://www.ncbi.nlm.nih.gov/pubmed/1957518 Prenatal marijuana use and neonatal outcome.
(abst 1991)
Analysis of Facial Shape in Children Gestationally Exposed to Marijuana, Alcohol, and/or Cocaine (abst - 1992)
http://pediatrics.aappublications.org/cgi/content/abstract/89/1/67?maxtoshow=&hits=80&RESULTFORM AT=&fulltext=marihuana&searchid=1&FIRSTINDEX=960&resourcetype=HWCIT
60- and 72-month follow-up of children prenatally exposed to marijuana, cigarettes, and alcohol: cognitive and language assessment. (abst 1992)
Prenatal Marijuana Exposure and Neonatal Outcomes in Jamaica: An Ethnographic Study (full - 1994) http://www.ukcia.org/research/can-babies.php Prenatal exposure to marihuana and tobacco during infancy, early and middle childhood: effects and an attempt at synthesis. (abst 1995)
236
Prenatal tobacco and marijuana use among adolescents: effects on offspring gestational age, growth, and morphology. (abst 1995)
An efficient new cannabinoid antiemetic in pediatric oncology.

(abst - 1995)
The effectiveness of Drug Abuse Resistance Education (project DARE): 5-year follow-up results. (abst 1996) http://www.ncbi.nlm.nih.gov/pubmed/8781009 Cannabis Cookies: a Cause of Coma.
(abst 1996)
Mortality Within the First 2 Years in Infants Exposed to Cocaine, Opiate, or Cannabinoid During Gestation (abst - 1997)
http://pediatrics.aappublications.org/cgi/content/abstract/100/1/79?maxtoshow=&hits=80&RESULTFORM AT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=640&resourcetype=HWCIT
Maternal cannabis use and birth weight: a meta-analysis Dr. Melanie Dreher, reefer researcher Cannabis and pregnancy Ganja mothers, ganja babies
(abst 1997)
http://www.ingentaconnect.com/content/carfax/cadd/1997/00000092/00000011/art00015
(interview - 1998)
http://www.cannabisculture.com/v2/articles/1404.html
(full - 1999) (news - 1999)
http://www.ukcia.org/research/CannabisAndPregnancy.php
http://www.cannabisculture.com/articles/1422.html
Marijuana and ADD- Therapeutic uses of Medical Marijuana in the treatment of ADD (news - 1999?) http://www.onlinepot.org/medical/add&mmj.htm Cannabis use falls among Dutch youth (abst - 2000) (anecdotal/news - 2001) (abst 2002)
Hemp Supplement Boosts Body AND Mind
http://pr.cannazine.co.uk/201006011282/green/eco-news/hemp-supplement-boosts-body-and-mind.html
Maternal use of cannabis and pregnancy outcome.

Recipe For Trouble
Comparison of meconium and neonatal hair analysis for detection of gestational exposure to drugs of abuse (full - 2003)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1721515/pdf/v088p00F98.pdf
237
Experiences with THC-treatment in children and adolescents

(abst - 2003)
Effect of maternal under-nutrition on pup body weight and hypothalamic endocannabinoid levels. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12678501 Endocannabinoids and food intake: newborn suckling and appetite regulation in adulthood. (full - 2005) http://ebm.rsmjournals.com/cgi/content/full/230/4/225 The cannabinoid system and its importance in the perinatal period
(abst 2005)
Treatment with CBD in oily solution of drug-resistant paediatric epilepsies. (abst - 2005)
http://www.cannabismed.org/studies/ww_en_db_study_show.php?s_id=173&&search_pattern=EPILEPSY
Endocannabinoids potently protect the newborn brain against AMPA-kainate receptormediated excitotoxic damage (full - 2006)
A preliminary DTI study showing no brain structural change associated with adolescent cannabis use (full - 2006)
Determination of the prevalence of drug misuse by meconium analysis

(full - 2006)
The Mental Health Risks of Adolescent Cannabis Use
(full - 2006)
Moderate cannabis use not harmful to the brain of adolescents, M R I study finds (news - 2006)
Oily fish makes 'babies brainier'
(news - 2006) (hemp seed- at the end)
Cannabis is a First-Line Treatment for Childhood Mental Disorders (news - 2006)

http://www.counterpunch.org/mikuriya07082006.html
Dreher's Jamaican Pregnancy Study
(news - 2006)
http://www.november.org/stayinfo/breaking06/DreherStudy.html
No 'Smoking' Gun: Research Indicates Teen Marijuana Use Does Not Predict Drug, Alcohol Abuse (news - 2006) http://www.sciencedaily.com/releases/2006/12/061204123422.htm
238
Pot May Not Shrink Teens' Brains After All
(news - 2006)
http://www.medpagetoday.com/Neurology/GeneralNeurology/tb/3242
Some go without a cigarette: characteristics of cannabis users who have never smoked tobacco. (full - 2007) http://archpedi.ama-assn.org/cgi/content/full/161/11/1042 Illicit Drug Use in Young Adults and Subsequent Decline in General Health: The Coronary Artery Risk Development in Young Adults (CARDIA) Study (full - 2007)
Prevalence of gestational exposure to cannabis in a Mediterranean city by meconium analysis. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17953730 Teens who use only cannabis appear to function better than those who also use tobacco (news - 2007) http://www.news-medical.net/news/2007/11/06/32262.aspx Teens Who Smoke Marijuana But Not Tobacco Are Different From Other Teen Groups (news - 2007) http://www.sciencedaily.com/releases/2007/11/071105164453.htm Swiss Study Finds Marijuana Use Alone May Benefit Some Teens
http://www.foxnews.com/story/0,2933,308258,00.html
(news - 2007)
Are Cigarettes More of a Drag on Teens than Marijuana?
(news - 2007) (news 2007)
http://www.scientificamerican.com/article.cfm?id=are-cigarettes-more-of-a
Breathe, Push, Puff? Pot Use and Pregnancy: A Review of the Literature
Marijuana Use by Young People: The Impact of State Medical Marijuana Laws (full - 2008) http://www.mpp.org/assets/pdfs/general/TeenUseReport_0608.pdf Volumetric MRI Study of Brain in Children With Intrauterine Exposure to Cocaine, Alcohol, Tobacco, and Marijuana (full - 2008)
http://pediatrics.aappublications.org/cgi/reprint/121/4/741?maxtoshow=&hits=80&RESULTFORMAT=&f ulltext=marihuana&searchid=1&FIRSTINDEX=400&resourcetype=HWCIT
The association between anxiety and alcohol versus cannabis abuse disorders among adolescents in primary care settings (full - 2008)
http://fampra.oxfordjournals.org/cgi/content/full/25/5/321
Characteristics of Adolescents Who Use Cannabis But Not Tobacco

http://forum.grasscity.com/showthread.php?p=11734799#post11734799
(news - 2008) (news - 2008)
Medical marijuana: a surprising solution to severe morning sickness
http://current.com/items/89174292_medical-marijuana-a-surprising-solution-to-severe-morningsickness.htm
239
When Your Kid Smokes Pot
(news 2008) (full - 2009)
http://mensnewsdaily.com/2010/08/08/when-your-kid-smokes-pot/
Relief-oriented use of marijuana by teens
Maternal tobacco, cannabis and alcohol use during pregnancy and risk of adolescent psychotic symptoms in offspring. (full - 2009)
The influence of substance use on adolescent brain development.

(full - 2009)
Cannabis use and deliberate self-harm in adolescence: a comparative analysis of associations in England and Norway. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19813111/abstract/Cannabis_use_and_deliberate_s elf_harm_in_adolescence:_a_comparative_analysis_of_associations_in_England_and_Norway_
Cannabis use and destructive periodontal diseases among adolescents (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19236530/abstract/Cannabis_use_and_destructive_ periodontal_diseases_among_adolescents_
Urinary toxicological screening: Analytical interference between niflumic acid and cannabis. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19716686/abstract/%5BUrinary_toxicological_scre ening:_Analytical_interference_between_niflumic_acid_and_cannabis_%5D
Accidental cannabis poisoning in children: experience of the Marseille poison center (abst 2009) http://www.ncbi.nlm.nih.gov/pubmed/19541448 Is moderate substance use associated with altered executive functioning in a populationbased sample of young adults? (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19946940/full_citation/Is_moderate_substance_use _associated_with_altered_executive_functioning_in_a_population_based_sample_of_young_adults
Long-term consequences of URB597 administration during adolescence on cannabinoid CB1 receptor binding in brain areas. (abst 2009)
White Matter Integrity in Adolescents with Histories of Marijuana Use and Binge Drinking. (abst - 2009)
Cannabis and tobacco use: where are the boundaries? A qualitative study on cannabis consumption modes among adolescents. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19515745/full_citation/Cannabis_and_tobacco_use :_where_are_the_boundaries_A_qualitative_study_on_cannabis_consumption_modes_among_adolescents _
240
Herbal Remedy: Teens Often Use Cannabis For Relief, Not Recreation, Study Finds (news - 2009) http://www.sciencedaily.com/releases/2009/04/090422191724.htm Maternal Marijuana use not Associated with Psychotic Symptoms , but Alcohol is (news - 2009)
Why I Give My 9-year-old Pot
(news/annecdotal - 2009) (news/anecdotal - 2009)
Why I Give My 9-Year-Old Pot, Part II
Uni-Morbid and Co-Occurring Marijuana and Tobacco Use: Examination of Concurrent Associations with Negative Mood States (full 2010)
The Maternal Lifestyle Study: Sleep Problems in Children with Prenatal Substance Exposure (full 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917192/?tool=pubmed Learning and memory performances in adolescent users of alcohol and marijuana: interactive effects. (full 2010)
PTSD contributes to teen and young adult cannabis use disorders.

(full 2010)
Cannabis withdrawal severity and short-term course among cannabis-dependent adolescent and young adult inpatients (abst - 2010)
http://www.unboundmedicine.com/medline/ebm/record/19783382/abstract/Cannabis_withdrawal_severity_ and_short_term_course_among_cannabis_dependent_adolescent_and_young_adult_inpatients_
The cannabinoid WIN55212-2 promotes neural repair after neonatal hypoxia-ischemia. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/21115947 Cannabis Use and Obesity and Young Adults ( abst - 2010)
http://informahealthcare.com/doi/abs/10.3109/00952990.2010.500438
A short-term, quasi-experimental evaluation of D.A.R.E.'s revised elementary school curriculum. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/21038762 12 Year Olds More Likely to Use Potentially Deadly Inhalants Than Cigarettes or Marijuana (news - 2010) http://www.sciencedaily.com/releases/2010/03/100312144534.htm 'Marijuana is helping my 9-year-old (news/anecdotal - 2010)
http://theweek.com/article/index/202109/Marijuana_is_helping_my_9yearold
241
Why I Give My 9-Year-Old Pot, Part 3
(news - 2010)
Teen Pot Smoking Won't Lead to Other Drugs as Adults
(news - 2010)
Marijuana May Offset Alcohol-Induced Cognitive Impairment Among Teens (news 2010) http://www.norml.org/index.cfm?Group_ID=8378 Pregnant Women Smoking Pot Could Reduce Infant Mortality (news - 2010)
http://www.opposingviews.com/i/pregnant-women-smoking-pot-could-reduce-infant-mortality
Early exposure to Environmental enrichment alters the expression of genes of the endocannabinoid system (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21419109/abstract/Early_exposure_to_Environme ntal_enrichment_alters_the_expression_of_genes_of_the_endocannabinoid_system_
History of cannabis use is not associated with alterations in striatal dopamine D2/D3 receptor availability. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21890594 Some features of teenage beer alcoholism combined with hashish addiction (abst 2011)
The social contagion effect of marijuana use among adolescents.

(full 2011)
Gender differences in adolescent marijuana use and associated psychosocial characteristics. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21769049 Accidental cannabis poisoning in children: report of four cases in a tertiary care center from southern Spain (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21283933/abstract/%5BAccidental_cannabis_pois oning_in_children:_report_of_four_cases_in_a_tertiary_care_center_from_southern_Spain%5D_
Prolonged coma in a child due to hashish ingestion with quantitation of THC metabolites in urine. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/20634020/abstract/Prolonged_coma_in_a_child_d ue_to_hashish_ingestion_with_quantitation_of_THC_metabolites_in_urine_
Pediatric cannabinoid hyperemesis: two cases.

(abst 2011)
(abst 2011)
Rural adolescent alcohol, tobacco, and illicit drug use: a comparison of students in victoria, australia, and washington state, United States. (abst 2011)
242
The association between early conduct problems and early marijuana use in college students. (abst 2011) http://marijuana.researchtoday.net/archive/8/9/4850.htm Father: Medical marijuana eased pain of my cancer-battling son
(anecdotal 2011)
The Kids Are All Right, Even if Their Parents Grow Pot
(news 2011)
http://www.parentdish.com/2011/07/27/the-kids-are-all-right-even-if-their-parents-grow-pot/
Legalizing Medical Marijuana Does Not Increase Use Among Youth, Study Suggests (news - 2011) http://www.sciencedaily.com/releases/2011/11/111102161047.htm 'Fake Marijuana' May Trigger Heart Trouble in Teens Are smart kids more likely to use drugs? Why I Give My Autistic Son Pot, Part 4
(news 2011)
http://health.yahoo.net/news/s/hsn/fakemarijuanamaytriggerhearttroubleinteens
(news 2011) (news 2011)
http://news.yahoo.com/smart-kids-more-likely-drugs-160000571.html
High Childhood IQ Linked to Subsequent Illicit Drug Use, Research Suggests (news 2011) http://www.sciencedaily.com/releases/2011/11/111114221018.htm Study: Legal Medical Marijuana Doesn't Encourage Kids to Smoke More Pot (news 2011) http://news.gather.com/viewArticle.action?articleId=281474980744307
CHOLERA Differential cholera-toxin sensitivity of supraspinal antinociception induced by the cannabinoid agonists delta9-THC, WIN 55,212-2 and anandamide in mice. (abst 1999) http://www.ncbi.nlm.nih.gov/pubmed/10218903 An endogenous cannabinoid tone attenuates cholera toxin-induced fluid accumulation in mice. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12949722 Marijuana for cholera therapy (letter 2005)
https://www.cell.com/trends/pharmacological-sciences/fulltext/S0165-6147%2805%2900266-X
243
CHOLESTEROL Cannabinoids impair the formation of cholesteryl ester in cultured human cells. (full 1981) http://atvb.ahajournals.org/cgi/reprint/1/6/449 Cholesterol-induced stimulation of platelet aggregation is prevented by a hempseedenriched diet. (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/18418423 Cannabis plant extracts could potentially form the basic ingredients for a market-leading diabetes drug (news 2009)
The Non-Psychoactive Plant Cannabinoid, Cannabidiol Affects Cholesterol MetabolismRelated Genes in Microglial Cells. (abst 2011)
The effects of hempseed meal intake and linoleic acid on Drosophila models of neurodegenerative diseases and hypercholesterolemia. (abst 2011)
The effect of dietary hempseed on atherogenesis and contractile function in aortae from hypercholesterolemic rabbits. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21893466
CHRONIC FATIGUE SYNDRONE A Practical treatise on nervous exhaustion (neurasthenia) aka Chronic Fatigue Syndrome (full 1894)
http://www.scribd.com/doc/49652565/Chronic-Fatigue-Syndrome-Cannabis-Treatment-1894
COGNATIVE EFFECTS- see IQ
COLITIS Ulcerative Colitis and Marijuana (letter - 1990)

http://www.druglibrary.org/schaffer/hemp/medical/colitis1.htm
Agonists of cannabinoid receptor 1 and 2 inhibit experimental colitis induced by oil of mustard and by dextran sulfate sodium. (full 2006)
http://ajpgi.physiology.org/content/291/2/G364.long
244
Ulcerative colitis in AKR mice is attenuated by intraperitoneally administered anandamide. (full 2008)
Targeting endocannabinoid degradation protects against experimental colitis in mice: involvement of CB1 and CB2 receptors. (abst 2008)
Activation of the cannabinoid 2 receptor (CB2) protects against experimental colitis. (full - 2009) http://onlinelibrary.wiley.com/doi/10.1002/ibd.20960/full Ulcerative Colitis Induces Changes on the Expression of the Endocannabinoid System in the Human Colonic Tissue (full - 2009)
Cannabidiol, a safe and non-psychotropic ingredient of the marijuana plant Cannabis sativa, is protective in a murine model of colitis. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19690824/abstract/Cannabidiol_a_safe_and_non_p sychotropic_ingredient_of_the_marijuana_plant_Cannabis_sativa_is_protective_in_a_murine_model_of_c olitis_
Cannabis for Ulcerative Colitis and Crohn's Disease treatment
(news - 2009)
http://www.news-medical.net/news/20091217/Cannabis-for-Ulcerative-Colitis-and-Crohns-Diseasetreatment.aspx
Mice lacking cannabinoid CB1-, CB2-receptors or both receptors show increased susceptibility to trinitrobenzene sulfonic acid (TNBS)-induced colitis. (full 2010)
The effects of Delta-tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis. (full - 2010)
The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/21080464 Cannabidiol Reduces Intestinal Inflammation through the Control of Neuroimmune Axis (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232190/?tool=pubmed Increasing endogenous 2-arachidonoylglycerol levels counteracts colitis and related systemic inflammation. (abst 2011)
245
-Caryophyllene inhibits dextran sulfate sodium-induced colitis in mice through CB2 receptor activation and PPAR pathway. (abst 2011)
Alternative targets within the endocannabinoid system for future treatment of gastrointestinal diseases. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21876860 Cannabinoid receptor-2 (CB2) agonist ameliorates colitis in IL-10(-/-) mice by attenuating the activation of T cells and promoting their apoptosis. (abst 2011)
COPD/ CHRONIC OBSTRUCTIVE PUMONARY DISEASE Heavy Habitual Marijuana Smoking Does Not Cause an Accelerated Decline in FEV with Age (full - 1997)
http://www.drugtext.org/library/research/cannabis/respiration/respiration02/resp02.htm
Marijuana. Respiratory tract effects.

(abst - 1997) (news - 1997)
Heavy Long-Term Marijuana Use Does Not Impair Lung Function

http://www.erowid.org/plants/cannabis/cannabis_media7.shtml
The cannabinoid receptor agonist WIN 55212-2 inhibits neurogenic inflammations in airway tissues. (full 2005) http://www.jstage.jst.go.jp/article/jphs/98/1/77/_pdf THC effective in appetite and weight loss in severe lung disease (COPD)
(news - 2005)
Researchers to test if cannabis ingredient can help COPD patients
(news - 2005)
http://www.thehempire.com/index.php/cannabis/news/researchers_to_test_if_cannabis_ingredient_can_hel p_copd_patients
Effects of Marijuana Smoking on Pulmonary Function and Respiratory Complications: A Systematic Review (full - 2007)
No Decrease in Pulmonary Function Associated with Long-Term Cannabis Smoking, Study Says (news - 2007) http://www.illinoisnorml.org/content/view/366/27/ Marijuana and chronic obstructive lung disease: a population-based study (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665947/?tool=pmcentrez
246
US Patent Application 20090197941 - Pharmaceutical Compositons for the Treatment of Chronic Obstructive Pulmonary Disease (full 2009)
Does smoking marijuana increase the risk of chronic obstructive pulmonary disease? (article - 2009) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2665954&tool=pmcentrez Smoking Pot, Cigarettes Ups COPD Risk (news - 2009) (full - 2010)
http://www.webmd.com/news/20090413/smoking-pot-cigarettes-ups-copd-risk
Effects of cannabis on lung function: a population-based cohort study.

http://erj.ersjournals.com/content/35/1/42.long
Effects of smoking cannabis on lung function

(full 2011)
Cannabinoid effects on ventilation and breathlessness: A pilot study of efficacy and safety (abst 2011)
http://crd.sagepub.com/content/early/2011/01/23/1479972310391283.abstract
Beneficial effects of cannabinoids (CB) in a murine model of allergen-induced airway inflammation: role of CB1/CB2 receptors. (abst 2011)
Marijuana Smoke Not as Damaging as Tobacco, Says Study
(news - 2012)
http://news.yahoo.com/marijuana-smoke-not-damaging-tobacco-says-study-204709671--abc-news.html
COUGH Inhibition of guinea-pig and human sensory nerve activity and the cough reflex in guineapigs by cannabinoid (CB2) receptor activation. (full - 2003)
Patent 6974568 - Treatment for cough
(full - 2005)
Effect of N-arachidonoyl-(2-methyl-4-hydroxyphenyl) amine (VDM11), an anandamide transporter inhibitor, on capsaicin-induced cough in mice (full - 2006)
Novel treatment for cough
(full - 2006)
http://appft1.uspto.gov/netacgi/nphParser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.html&r=1& f=G&l=50&s1=%2220060013777%22.PGNR.&OS=DN/20060013777&RS=DN/20060013777
247
Cannabis Cough Cure
(news - 2006) (abst 2011)
http://www.thehempire.com/index.php/cannabis/news/cannabis_cough_cure
G-protein coupled receptors regulating cough.

COWPOX "Recreational" drug abuse associated with failure to mount a proper antibody response after a generalised orthopoxvirus infection. (abst 2011)
CP 47,497 - a synthetic cannabinoid, CB1 & CB2 agonist Cannabimimetic activity from CP-47,497, a derivative of 3-phenylcyclohexanol (abst - 1982)
http://jpet.aspetjournals.org/content/223/2/516.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=Hexahydrocannabinol&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
The Conformational Properties of the Highly Selective Cannabinoid Receptor Ligand CP-55,940 (full - 1996)
http://www.jbc.org/content/271/18/10640.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=Hex ahydrocannabinol&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
Cannabinoids augment the release of neuropeptide Y in the rat hypothalamus (abst 2005) http://www.sciencedirect.com/science/article/pii/S0028390805001668 Withdrawal Phenomena and Dependence Syndrome After the Consumption of "Spice Gold" (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719097/?tool=pmcentrez Spice drugs: cannabinoids as a new designer drugs. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19718488/abstract/%5BSpice_drugs:_cannabinoid s_as_a_new_designer_drugs_%5D
Spice: a never ending story?
(abst 2009)
Pharmacological properties and dependence liabilities of synthetic cannabinoids (abst 2010)

http://www.unboundmedicine.com/medline/ebm/record/20681249/abstract/%5BPharmacological_propertie s_and_dependence_liabilities_of_synthetic_cannabinoids%5D_
248
Monitoring of herbal mixtures potentially containing synthetic cannabinoids as psychoactive compounds. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20857386 THIS ISN'T YOUR MOTHER'S SPICE (news - 2010)
Now, There's a Test for That -- Norchem's "Fake Marijuana" Test Reveals Significantly Increased Abuse of Spice/K2 (news - 2010)
http://www.marketwire.com/press-release/Now-Theres-Test-That-Norchems-Fake-Marijuana-TestReveals-Significantly-Increased-Abuse-1356247.htm
College students and use of K2: an emerging drug of abuse in young persons (full 2011) http://www.substanceabusepolicy.com/content/6/1/16 Marijuana-based Drugs: Innovative Therapeutics or Designer Drugs of Abuse? (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139381/?tool=pubmed Beyond THC: The New Generation of Cannabinoid Designer Drugs.
(full 2011)
Investigating a not-so-natural high. (full 2011) http://pubs.acs.org/doi/full/10.1021/ac900564u CP47,497-C8 and JWH073, commonly found in 'Spice' herbal blends, are potent and efficacious CB(1) cannabinoid receptor agonists. (abst 2011)
A method for CP 47, 497 a synthetic non-traditional cannabinoid in human urine using liquid chromatography tandem mass spectrometry. (abst 2011)
Synthetic cannabinoids in oral fluid.
(abst 2011)
Cytotoxicity of synthetic cannabinoids found in "Spice" products: The role of cannabinoid receptors and the caspase cascade in the NG 108-15 cell line. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21907772 Use of high-resolution accurate mass spectrometry to detect reported and previously unreported cannabinomimetics in "herbal high" products. (abst 2011)

The emergence and analysis of synthetic cannabinoids.

(abst 2011)
249
Chemicals Used in "Spice" and "K2" Type Products Now Under Federal Control and Regulation (news 2011) http://www.justice.gov/dea/pubs/pressrel/pr030111.html
CP 50,556-1 / LEVONANTRADOL synthetic, CB1 & CB2 agonist Clinical experience with levonantradol hydrochloride in the prevention of cancer chemotherapy-induced nausea and vomiting. (abst 1981)
Randomised Clinical Trial of Levonantradol and Chlorpromazine in the Prevention of Radiotherapy-induced Vomiting. (abst - 1982)
Levonantradol, a new antiemetic with a high rate of side-effects for the prevention of nausea and vomiting in patients receiving cancer chemotherapy. (abst 1982)
Respiratory and cardiovascular depressant effects of nabilone, N-methyllevonantradol and delta 9-tetrahydrocannabinol in anesthetized cats. (abst - 1983)
Thujone exhibits low affinity for cannabinoid receptors but fails to evoke cannabimimetic responses. (abst 1999) http://www.ncbi.nlm.nih.gov/pubmed/10080239 Delta(9)-tetrahydrocannabinol and synthetic cannabinoids prevent emesis produced by the cannabinoid CB(1) receptor antagonist/inverse agonist SR 141716A. (full 2001)
Marijuana-based Drugs: Innovative Therapeutics or Designer Drugs of Abuse? (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139381/?tool=pubmed
250
CP 55,940 - a synthetic cannabinoid-CB1 & CB2 agonist Molecular cloning of a human cannabinoid receptor which is also expressed in testis (abst 1991) http://pharmgkb.org/pmid/1718258 Cannabinoid receptor agonists inhibit Ca current in NG108-15 neuroblastoma cells via a pertussis toxin-sensitive mechanism. (full - 1992)
Involvement of Dynorphin B in the Antinociceptive Effects of the Cannabinoid CP55,940 in the Spinal Cord (full - 1997) http://jpet.aspetjournals.org/content/281/2/730.full Cannabinoid Receptor Agonists Protect Cultured Rat Hippocampal Neurons from Excitotoxicity (full - 1998) http://molpharm.aspetjournals.org/content/54/3/459.full Potent Effects of a Selective Cannabinoid Receptor Agonist on Some Guinea Pig Medial Vestibular Nucleus Neurons. (abst 1998)
http://medical-journals.healia.com/doc/9650841/Potent-effects-of-a-selective-cannabinoid-receptoragonist-on-some-guinea-pig-medial-vestibular-nucleus-neurons
The role of cannabinoid receptors in intestinal motility, defaecation and diarrhoea in rats (abst - 1999) http://www.ncbi.nlm.nih.gov/pubmed/10611417 Effects of cannabinoid receptor agonists on neuronally-evoked contractions of urinary bladder tissues isolated from rat, mouse, pig, dog, monkey and human (full - 2000)
Cannabinoid effects on anxiety-related behaviours and hypothalamic neurotransmitters. (abst - 2001) http://www.ncbi.nlm.nih.gov/pubmed/11566149 The potent emetogenic effects of the endocannabinoid, 2-AG (2-arachidonoylglycerol) are blocked by delta(9)-tetrahydrocannabinol and other cannnabinoids. (full 2002)
Chronic Morphine Modulates the Contents of the Endocannabinoid, 2-Arachidonoyl Glycerol, in Rat Brain (full - 2003)
251
CANNABINOIDS ALTER RECOGNITION MEMORY IN RATS

(full 2003)
Synergistic Interactions between Cannabinoids and Environmental Stress in the Activation of the Central Amygdala (full - 2005)
Endocannabinoids -- The Brain's Cannabis -- Demonstrate Novel Modes Of Action To Stress (news - 2005) http://www.sciencedaily.com/releases/2005/07/050720065810.htm Chronologically overlapping occurrences of nicotine-induced anxiety- and depressionrelated behavioral symptoms: effects of anxiolytic and cannabinoid drugs (full - 2007)

(full - 2007)
The cannabinoid CP55,940 prolongs survival and improves locomotor activity in Drosophila melanogaster against paraquat: implications in Parkinson's disease. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18538428
252
Distribution and function of cannabinoid receptors 1 and 2 in the rat, monkey and human bladder. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19237169 Attenuation of morphine antinociceptive tolerance by a CB(1) receptor agonist and an NMDA receptor antagonist: Interactive effects. (full 2010)
Cannabinoid inhibition of macrophage migration to the trans-activating (Tat) protein of HIV-1 is linked to the CB(2) cannabinoid receptor. (full 2010)
Rimonabant-induced Delta9-tetrahydrocannabinol withdrawal in rhesus monkeys: discriminative stimulus effects and other withdrawal signs. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20375197/abstract/Rimonabant_induced_Delta9_te trahydrocannabinol_withdrawal_in_rhesus_monkeys:_discriminative_stimulus_effects_and_other_withdra wal_signs_
Protective effects of the synthetic cannabinoids CP55,940 and JWH-015 on rat brain mitochondria upon paraquat exposure. (abst 2010)
Cytotoxicity of synthetic cannabinoids found in "Spice" products: The role of cannabinoid receptors and the caspase cascade in the NG 108-15 cell line. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21907772 Chronic -tetrahydrocannabinol treatment in rhesus monkeys: differential tolerance and cross-tolerance among cannabinoids. (abst 2011)
The schizophrenia susceptibility gene neuregulin 1 modulates tolerance to the effects of cannabinoids. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/20701826/abstract/The_schizophrenia_susceptibilit y_gene_neuregulin_1_modulates_tolerance_to_the_effects_of_cannabinoids_
253
CROHN'S - see BOWEL DISODERS
CRUETZFELDT-JACOB DISEASE - see MAD COW DISEASE
CT-3 - synthetic also see AJULMIC ACID Analgesic effect of the synthetic cannabinoid CT-3 on chronic neuropathic pain: a randomized controlled trial. (full - 2003)
http://jama.amaassn.org/cgi/content/full/290/13/1757?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&se archid=1&FIRSTINDEX=0&resourcetype=HWCIT
Symptomatic treatment of multiple sclerosis using cannabinoids: recent advances. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17868014
CYSTIC FIBROSIS I have Cystic fibrosis (anecdotal - no date) (abst 1987)

http://www.masscann.org/consumption/73-medicine/314-i-have-cystic-fibrosis
Recreational use of psychoactive drugs by patients with cystic fibrosis.

Cannabinoids and cystic fibrosis: a novel approach to etiology and therapy. (full - 2002)
The endocannabinoid-CB receptor system: Importance for development and in pediatric disease. (abst - 2004) http://www.ncbi.nlm.nih.gov/pubmed/15159678 Peripheral, but not central effects of cannabidiol derivatives: mediation by CB(1) and unidentified receptors. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/15910887 Vaporized marijuana effect on CF. NOT smoking (forum post - 2007) (case study/ad- 2009)
http://www.topix.com/forum/health/cystic-fibrosis/TBQ56B1VNGGAODTKA
Marijuana (Cannabis) and Cystic Fibrosis; A Case Study
http://mcsocal.com/blog/marijuana-cannabis-and-cystic-fibrosis-a-case-study/
254
"Bong lung" in cystic fibrosis: a case report
(full - 2010)
CYSTITIS Cannabinoid rotation in a young woman with chronic cystitis

(abst - 2003)
Marijuana-Derived Drug Suppresses Bladder Overactivity And Irritation In Animal Models (news - 2005) http://www.sciencedaily.com/releases/2005/09/050906080225.htm Marijuana-Derived Drug Promises Hope In Treating Bladder Infection (news 2005)
http://www.bio-medicine.org/medicine-news/Marijuana-Derived-Drug-Promises-Hope-In-TreatingBladder-Infection-4724-1/

(news - 2006)
DENTISTRY - see TEETH
DEPRESSION The perceived effects of smoked cannabis on patients with multiple sclerosis. (abst - 1997) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=13 Anxiety with Depression Research Review (full - 2000) (full - 2001)
http://www.ukcia.org/research/AnxietyWithDepressionResearchReview.pdf

Association between cannabis use and depression may not be causal, study says (news - 2004)
Cannabinoids promote hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects (full - 2005) http://www.jci.org/cgi/content/full/115/11/3104
255
Antidepressant-like activity by blockade of anandamide hydrolysis (full - 2005)

Depression in Parkinson's disease is related to a genetic polymorphism of the cannabinoid receptor gene (CNR1) (full - 2005)
New Antidepressant Drug Increases 'Brain's Own Cannabis'

(news - 2005)
Cannabis' Acts as Antidepressant Cannabis And Depression Research
(news - 2005) (news - 2005) (news 2005)
http://www.thehempire.com/index.php/cannabis/news/cannabis_acts_as_antidepressant
http://www.thehempire.com/index.php/cannabis/news/cannabis_and_depression_research
High-dose cannabis stimulates growth of brain cells in rats
Good News For The Medical Marijuana Movement: Pot Proliferates Brain Cells And Boosts Mood (news - 2005) http://www.sciencedaily.com/releases/2005/10/051014073523.htm Marijuana might cause new cell growth in the brain
(news 2005)
Surprising Brain Effects From Pot-Like Drug Decreased depression in marijuana users.
(news 2005) (full - 2006)
http://www.webmd.com/mental-health/news/20051013/surprising-brain-effects-from-pot-like-drug
http://www.doctordeluca.com/Library/WOD/WPS3-MedMj/DecreasedDepressionInMjUsers05.pdf
The synthetic cannabinoid nabilone improves pain and symptom management in cancer patients (abst - 2006) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=177 Marijuana use and depression among adults: Testing for causal associations. (abst - 2006)
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=1696834 8&ordinalpos=412&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
Do patients use marijuana as an antidepressant?
(abst - 2006)
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=9160645 &ordinalpos=32&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
256
A possible role for the endocannabinoid system in the neurobiology of depression (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169225/?tool=pubmed Chronologically overlapping occurrences of nicotine-induced anxiety- and depressionrelated behavioral symptoms: effects of anxiolytic and cannabinoid drugs (full - 2007)
Cannabinoids elicit antidepressant-like behavior and activate serotonergic neurons through the medial prefrontal cortex. (full - 2007)
Antidepressant-like activity of the fatty acid amide hydrolase inhibitor URB597 in a rat model of chronic mild stress. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17511970 Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep. (abst - 2007) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=190 Marijuana-Like Brain Chemicals Work As Antidepressant
(news - 2007)
Marijuana chemical may treat depression
(news - 2007)
http://www.healthcentral.com/depression/news-268391-98.html
Cannabis: Potent Anti-Depressant In Low Doses, Worsens Depression At High Doses (news - 2007) http://www.sciencedaily.com/releases/2007/10/071023183937.htm Synthetic form of THC is an effective anti-depressant at low doses
http://www.news-medical.net/news/2007/10/24/31666.aspx?page=2
(news - 2007)
Treating depression with cannabinoids
(full - 2008)
Animal research highlights a therapeutic potential of cannabinoids for the treatment of depression (full - 2008) http://www.cannabis-med.org/english/journal/en_2008_02_1.pdf Protracted cannabinoid administration elicits antidepressant behavioral responses in rats: role of gender and noradrenergic transmission. (abst - 2009)
Cannabis and suicide: longitudinal study.

(abst - 2009)
Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L. (full 2010)
Brain CB2 Receptors: Implications for Neuropsychiatric Disorders

(full 2010)
257
Genes differentially expressed in CB1 knockout mice: involvement in the depressive-like phenotype. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20692131 Deficiency in Endocannabinoid Signaling in the Nucleus Accumbens Induced by Chronic Unpredictable Stress (abst - 2010)
Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions. (abst 2011) http://www.nature.com/neuro/journal/v14/n3/full/nn.2736.html Endocannabinoid system dysfunction in mood and related disorders.
(abst 2011)
Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21238581 Cannabinoids and emotionality: a neuroanatomical perspective.
(abst 2011) (news - 2011)
Deficiency of Dietary Omega-3 May Explain Depressive Behaviors
http://www.thefreelibrary.com/Deficiency+of+Dietary+Omega-3+May+Explain+Depressive+Behaviors.a0248155576
Omega-3 PUFA Deficiency Abolishes Endocannabinoid-Linked Neuronal Functions (news - 2011) http://www.fatsoflife.com/article.php?nid=1&edition=this&id=1837&issueid=85 Scientific research reveals brain alterations linking omega 3 deficit with depression (news 2011) http://www.physorg.com /news/2011-02-scientific-reveals-brain-linking-omega.html A deficiency of dietary omega-3 may explain depressive behaviors A Brain Wrought Without Omega-3 (news 2011) (news 2011) (news - 2011)
http://www.physorg.com/news/2011-01-deficiency-dietary-omega-depressive-behaviors.html
http://www.schizophreniaforum.org/new/detail.asp?id=1646
Omega-3 deficiency disrupts cannibinoid receptor function in brain
http://www.wellsphere.com/general-medicine-article/omega-3-deficiency-disrupts-cannibinoid-receptorfunction-in-brain/1347465
258
DERMATITIS Allergenic properties of naturally occurring cannabinoids.

(abst - 1983) (full - 1999) (full 2003)
Hemp Seed Oil : The Wonder Oil For the New Millennium The Endocannabinoid System in Human Keratinocytes
Histamine induced responses are attenuated by a cannabinoid receptor agonist in human skin. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12835895 Hemp-seed and olive oils: their stability against oxidation and use in O/W emulsions. (abst 2004) http://www.ncbi.nlm.nih.gov/pubmed/16130045 Efficacy of dietary hempseed oil in patients with atopic dermatitis.
(abst - 2005)
Anandamide Regulates Keratinocyte Differentiation by Inducing DNA Methylation in a CB1 Receptor-dependent Manner (full 2007)
Want Nice Skin? Then Smoke Cannabis!
(news 2007)
http://news.softpedia.com/news/Want-Nice-Skin-Then-Smoke-Cannabis-56803.shtml
Role seen for cannabis in helping to alleviate allergic skin disease (news - 2007)
Allergic Skin Disease Could Be Treated With Substance Found In Cannabis (news 2007) http://www.medicalnewstoday.com/releases/79889.php Hashing Out Allergic Contact Dermatitis Another Medical Use for Marijuana? (news - 2007)
http://dermatology.jwatch.org/cgi/content/full/2007/622/1?maxtoshow=&hits=80&RESULTFORMAT=&f ulltext=cannabinoid&searchid=1&FIRSTINDEX=1920&resourcetype=HWCIT
Cannabis May Help Alleviate Allergic Skin Disease

(news - 2007)
259
Constituents Of Hashish And Marijuana May Help To Fight Inflammation And Allergies (news - 2007) http://www.sciencedaily.com/releases/2007/06/070607171120.htm Cannabis compound reduces skin allergies in mice (news 2007)
http://www.newscientist.com/article/dn12016-cannabis-compound-reduces-skin-allergies-in-mice.html
Marijuana Might Help Cure Allergic Contact Dermatitis (a.k.a. Poison Ivy) (news - 2007) http://www.healthcentral.com/skin-cancer/c/83/12569/cure-aka-ivy/1/ Marijuana Skin Cream? (news - 2007) (news - 2007)
http://www.drugfree.org/join-together/drugs/marijuana-skin-cream
Cannabis for allergic contact dermatitis
Attenuation of Allergic Contact Dermatitis Through the Endocannabinoid System (full - 2008)
Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling. (full 2008)
http://www.fasebj.org/content/22/10/3685.long
Body's Own 'Cannabis (Marijuana)' Is Good For The Skin, Scientists Find (news - 2008) http://www.sciencedaily.com/releases/2008/07/080702160944.htm Substances Similar To The Body's Own 'Cannabis (Marijuana) Are Necessary For Healthy Skin And May Lead To New Skin Disease Treatments (news - 2008)
The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities (full - 2009)
The cannabinoid receptor CB2 exerts antifibrotic effects in experimental dermal fibrosis (full - 2009) http://www3.interscience.wiley.com/cgi-bin/fulltext/122290593/HTMLSTART Cannabinoid system in the skin - a possible target for future therapies in dermatology. (full - 2009) http://onlinelibrary.wiley.com/doi/10.1111/j.1600-0625.2009.00923.x/full Granny's cannabis skin ointment really did work, new study shows (news - 2009)
http://current.com/items/89838741_grannys-cannabis-skin-ointment-really-did-work-new-study-shows.htm
Falcarinol is a covalent cannabinoid CB1 receptor antagonist and induces pro-allergic effects in skin. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20206138
260

(abst 2010)
Hemp Seed Oil for Skin
(news 2010) (abst 2011)
http://www.livestrong.com/article/340189-hemp-seed-oil-for-skin/
Endocannabinoid signaling and epidermal differentiation.

DEXANABINOL - see HU-211
DIABETES Cannabidiol Preserves Retinal Neurons and Reduces Vascular Permeability in Experimental Diabetes (abst - 2004)
The effect of WIN 55,212-2, a cannabinoid agonist, on tactile allodynia in diabetic rats. (abst 2004) http://www.ncbi.nlm.nih.gov/pubmed/15519750 Cannabidiol lowers incidence of diabetes in non-obese diabetic mice
(full - 2005)
Activation of the Peripheral Endocannabinoid System in Human Obesity (full - 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228268/?tool=pmcentrez Gpr40 Gene Expression in Human Pancreas and Insulinoma. (abst 2005)
The Ffa Receptor Gpr40 Links Hyperinsulinemia, Hepatic Steatosis, and Impaired Glucose Homeostasis in Mouse. (abst 2005)
261
Regulation, Function, and Dysregulation of Endocannabinoids in Models of Adipose and -Pancreatic Cells and in Obesity and Hyperglycemia (full - 2006)
(full - 2006)
Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration. (abst 2006)
The Cannabinergic System as a Target for Anti-inflammatory Therapies (abst - 2006) http://www.ingentaconnect.com/content/ben/ctmc/2006/00000006/00000013/art00008 Non-Psychoactive Cannabinoid Reduces Incidence Of Diabetes, Study Says (news - 2006) http://www.norml.org/index.cfm?Group_ID=6909 Marijuana Compound May Help Stop Diabetic Retinopathy
(news - 2006) (news 2006) (news 2006)
Cannabidiol, a marijuana compound, may help stop diabetic retinopathy Marijuana Compound Offers Hope In Diabetic Retinopathy Prevention
http://www.xagena.it/news/medicinenews_net_news/549d841c3704e2b6a273a258dd0b6f17.html
http://www.bio-medicine.org/medicine-news/Marijuana-Compound-Offers-Hope-In-Diabetic-RetinopathyPrevention-8121-1/
Cannabidiol reduces the development of diabetes in an animal study Getting Eye On Cannabinoids (news - 2006)
(news - 2006)
http://www.thehempire.com/index.php/cannabis/news/getting_eye_on_cannabinoids
Marijuana compound could prevent eye damage in diabetics
(news - 2006)
http://www.thehempire.com/index.php/cannabis/news/marijuana_compound_could_prevent_eye_damage_i n_diabetics
Cannabidiol arrests onset of autoimmune diabetes in NOD mice
(full - 2007)
http://safeaccess.ca/research/pdf/WeissCBD_ArrestsDiabetesNeuropharmacology2007.pdf
262
Expression of Cannabinoid CB1 Receptors in Models of Diabetic Neuropathy (full - 2007)

Cannabidiol attenuates high-induced endothelial cell inflammatory response and barrier disruption (full - 2007)
US Patent Application 20070099987 - Treating or preventing diabetes with cannabidiol (full 2007) http://www.patentstorm.us/applications/20070099987/fulltext.html Role of cannabinoid CB2 receptors in glucose homeostasis in rats
(abst 2007)
The synthetic cannabinoid HU-210 attenuates neural damage in diabetic mice and hyperglycemic pheochromocytoma PC12 cells (abst - 2007)
Anticoagulant Effects of a Cannabis Extract in an Obese Rat Model

(abst - 2007)
Mediation of Cannabidiol anti-inflammation in the Retina by Equilibrative Nucleoside Transporter and A2A Adenosine Receptor (full - 2008)
The Role of Adipocyte Insulin Resistance in the Pathogenesis of Obesity-Related Elevations in Endocannabinoids (full 2008)
http://diabetes.diabetesjournals.org/content/57/5/1262.full?sid=00769f3d-54ab-451b-b69e-4650931c5e25
GPR119, a novel G protein-coupled receptor target for the treatment of type 2 diabetes and obesity (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268073/?tool=pmcentrez Endocannabinoid Dysregulation in the Pancreas and Adipose Tissue of Mice Fed With a High-fat Diet (full - 2008) http://www.nature.com/oby/journal/v16/n3/full/oby2007106a.html Neuroprotective effects of cannabidiol in endotoxin-induced uveitis: critical role of p38 MAPK activation. (full - 2008)
(full 2008)
Mediation of Cannabidiol Anti-inflammation in the Retina by Equilibrative Nucleoside Transporter and A2A Adenosine Receptor (full 2008)
Presence of functional cannabinoid receptors in human endocrine pancreas. (abst 2008)

263
Cannabidiol As a Putative Novel Therapy for Diabetic Retinopathy: A Postulated Mechanism of Action as an Entry Point for Biomarker-Guided Clinical Development. (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955420/?tool=pubmed Cannabinoids as novel anti-inflammatory drugs. (full - 2009)
The endocanabinnoid system and diabetes - critical analyses of studies conducted with rimonabant (full - 2009)
Biological effects of THC and a lipophilic cannabis extract on normal and insulin resistant 3T3-L1 adipocytes (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19345076/abstract/Biological_effects_of_THC_an d_a_lipophilic_cannabis_extract_on_normal_and_insulin_resistant_3T3_L1_adipocytes_
Anti-inflammatory effect of palmitoylethanolamide on human adipocytes.

(abst 2009)
Beneficial effects of a Cannabis sativa extract on diabetes induced neuropathy and oxidative stress. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19441010/abstract/Beneficial_effects_of_a_Canna bis_sativa_extract_treatment_on_diabetes_induced_neuropathy_and_oxidative_stress_
Cannabis plant extracts could potentially form the basic ingredients for a market-leading diabetes drug (news 2009)
Expression and function of cannabinoid receptors in mouse islets.

http://www.landesbioscience.com/journals/islets/LiISLETS2-5.pdf
( full 2010)
Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression. (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005548/?tool=pubmed Cannabinoid Receptor 1 Blockade Ameliorates Albuminuria in Experimental Diabetic Nephropathy (full 2010)
http://diabetes.diabetesjournals.org/content/59/4/1046.full?sid=0bc8e3fa-5275-4b19-8acc-4aec5dfac384
264
Cannabinoid Receptors are Coupled to Stimulation of Insulin Secretion from Mouse MIN6 -cells (full 2010)
http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowPDF&ArtikelNr=320527&Ausgabe=25 4555&ProduktNr=224332&filename=320527.pdf
Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients (full - 2010)
Cannabinoid receptor stimulation impairs mitochondrial biogenesis in mouse white adipose tissue, muscle, and liver: the role of eNOS, p38 MAPK, and AMPK pathways. (full 2010) http://diabetes.diabetesjournals.org/content/59/11/2826.long#sec-25 Cannabidiol protects retinal neurons by preserving glutamine synthetase activity in diabetes. (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925907/?tool=pubmed Cannabidiol Attenuates Cardiac Dysfunction, Oxidative Stress, Fibrosis, and Inflammatory and Cell Death Signaling Pathways in Diabetic Cardiomyopathy (full - 2010) http://www.natap.org/2010/newsUpdates/marijuana.pdf Rehashing endocannabinoid antagonists: can we selectively target the periphery to safely treat obesity and type 2 diabetes? (full 2010)
Novel GPR119 agonist AS1535907 contributes to first-phase insulin secretion in rat perfused pancreas and diabetic db/db mice. (abst 2010)
AS1907417, a novel GPR119 agonist, as an insulinotropic and -cell preservative agent for the treatment of type 2 diabetes. (abst 2010)
GPR119 agonists for the potential treatment of type 2 diabetes and related metabolic disorders. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/21094910 Diabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation. (abst 2010)

(news - 2010)
265
Cannabinoids inhibit and may prevent neuropathic pain in diabetes. Lab Notes: Pot Has Benefits for Diabetic Hearts
(news - 2010)
(news - 2010) (full 2011)
Cannabinoid receptor 2 signaling does not modulate atherogenesis in mice

Role for cannabinoid receptors in human proximal tubular hypertrophy. (full 2011)
Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21144973/abstract/Cannabidiol_attenuates_cardiac _dysfunction_oxidative_stress_fibrosis_and_inflammatory_and_cell_death_signaling_pathways_in_diabeti c_cardiomyopathy_
Central Endocannabinoid Signaling Regulates Hepatic Glucose Production and Systemic Lipolysis (abst 2011) http://diabetes.diabetesjournals.org/content/60/4/1055.abstract Cannabinoids Inhibit Insulin Receptor Signaling in Pancreatic -Cells (abst 2011)
http://diabetes.diabetesjournals.org/content/60/4/1198.abstract?sid=0bc8e3fa-5275-4b19-8acc4aec5dfac384
Acute cannabinoid receptor type 1 (CB1R) modulation influences insulin sensitivity by an effect outside the central nervous system in mice. (abst 2011)
Cannabinoid receptor agonists and antagonists stimulate insulin secretion from isolated human islets of Langerhans. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21564460/abstract/Cannabinoid_receptor_agonists _and_antagonists_stimulate_insulin_secretion_from_isolated_human_islets_of_Langerhans_
A role for the putative cannabinoid receptor GPR55 in the islets of Langerhans. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21885477 Protective Role of Cannabinoid Receptor Type 2 in a Mouse Model of Diabetic Nephropathy. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21810593 Cannabinoids and Endocannabinoids in Metabolic Disorders with Focus on Diabetes. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21484568/abstract/Cannabinoids_and_Endocannab inoids_in_Metabolic_Disorders_with_Focus_on_Diabetes_
Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21238581
266
GPR119 Regulates Murine Glucose Homeostasis Through Incretin Receptor-Dependent and Independent Mechanisms (abst 2011)
http://endo.endojournals.org/content/152/2/374.abstract?sid=c77be354-b90f-4368-9bb3-fea533824b24
Cannabidiol Dampens Streptozotocin-Induced Retinal Inflammation by Targeting of Microglial Activation (abst - 2011)
The cytoprotective effects of oleoylethanolamide in insulin-secreting cells do not require activation of GPR119. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22029844 The Endocannabinoid System: Plant-Derived Cannabinoids in Diabetes and Diabetic Complications. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22155112 Takeda moves potential first-in-class diabetes drug into phase III (news 2011)
DOWNS SYNDROME Glial expression of cannabinoid CB(2) receptors and fatty acid amide hydrolase are beta amyloid-linked events in Down's syndrome. (abst 2008)
DRIVING AND CANNABIS Comparison of the Effects of Marijuana and Alcohol on Simulated Driving Performance (full - 1969) http://www.onlinepot.org/medical/Dr_Tods_PDFs/s4_4.pdf Simulated Flying Performance After Marihuana Intoxication.
(abst 1976)
Marijuana effects on simulated flying ability.

(abst 1976)
267
Abstracts of several studies
(absts -1982 - 1998)
http://www.ukcia.org/research/medline/8.htm
The Incidence and Role of Drugs in Fatally Injured Drivers - DOT HS 808 065 (full - 1992) http://science.iowamedicalmarijuana.org/pdfs/driving/doths808065.pdf Marijuana And Actual Driving Performance (full - 1993)
http://science.iowamedicalmarijuana.org/pdfs/driving/doths808078.pdf
CANNABIS AND ROAD SAFETY: AN OUTLINE OF THE RESEARCH STUDIES TO EXAMINE THE EFFECTS OF CANNABIS ON DRIVING SKILLS AND ON ACTUAL DRIVING PERFORMANCE (full - c.1995)
http://www.ukcia.org/research/driving2.htm
Cannabis and driving
(abst - 1998)
http://www.ukcia.org/research/driving4.html
Marijuana, Alcohol and Actual Driving Performance - DOT HS 808 939 (full - 1999) http://science.iowamedicalmarijuana.org/pdfs/driving/doths808939.pdf University Of Toronto Study Shows Marijuana Not A Factor In Driving Accidents (news - 1999) http://www.sciencedaily.com/releases/1999/03/990325110700.htm The influence of cannabis on driving (full - 2000) (abst 2001)
http://www.ukcia.org/research/driving/TRL477.pdf
Cannabis use and traffic accidents in a birth cohort of young adults.

Drivers With THC in their Blood Have Only a Small Increased Risk to Cause an Accident (news - 2005)
Roadside sobriety tests and attitudes toward a regulated cannabis market.

(full 2007)
Developing limits for driving under cannabis.

(abst - 2007)
(abst - 2007)
Effects of THC on driving performance, physiological state and subjective feelings relative to alcohol. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18460360 Cannabis and Driving: A Scientific and Rational Review
(news - 2008)
268
Marijuana and Driving Not So Dangerous After All
(news - 2008)
http://www.autoevolution.com/news/marijuana-and-driving-not-so-dangerous-after-all-2756.html
Driving under the influence of cannabis: a 10-year study of age and gender differences in the concentrations of tetrahydrocannabinol in blood. (abst - 2008)
The effect of cannabis compared with alcohol on driving.

(full - 2009)
Sex Differences in the Effects of Marijuana on Simulated Driving Performance (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033009/?tool=pmcentrez The effects of cannabis and alcohol on simulated arterial driving: Influences of driving experience and task demand. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20380913/abstract/The_effects_of_cannabis_and_a lcohol_on_simulated_arterial_driving:_Influences_of_driving_experience_and_task_demand_
Study: Marijuana Has Little Effect On Driving

http://www.wfsb.com/health/23818577/detail.html
(news - 2010)
Hartford Hospital Studies Effects Of Marijuana Use On Driving Skills (news - 2010) http://www.ctnow.com/health/hc-marijuana-study0608-20100607,0,5896933.story Psychomotor Impairing Effects Of Cannabis Are Nominal In Experienced Users, Study Says (news 2010) http://www.norml.org/index.cfm?Group_ID=8404 Medical Marijuana Laws, Traffic Fatalities, and Alcohol Consumption
http://ftp.iza.org/dp6112.pdf
(full 2011)
The prevalence of cannabis-involved driving in California.
(abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/22101027/abstract/The_prevalence_of_cannabis_i nvolved_driving_in_California_
Alcohol, psychoactive drugs and fatal road traffic accidents in Norway: a case-control study. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21376919/abstract/Alcohol_psychoactive_drugs_a nd_fatal_road_traffic_accidents_in_Norway:_a_case_control_study_
Study shows medical marijuana laws reduce traffic deaths

http://www.eurekalert.org/pub_releases/2011-11/uocd-ssm112911.php
(news 2011) (news - 2011)
Why Medical Marijuana Laws Reduce Traffic Deaths
It Turns Out That Smoking Marijuana May Actually Make You A Safer Driver (news 2011)
http://articles.businessinsider.com/2011-12-19/news/30533159_1_medical-marijuana-beer-sales-trafficfatalities
269
Colorados 5ng/ml per se DUID bill dies again as new research backs higher thresholds for regular users (news 2011)
http://stash.norml.org/colorados-5ngml-per-se-duid-bill-dies-again-as-new-research-backs-higherthresholds-for-regular-users
DRONABINOL a synthetic THC in sesame oil also see MARINOL Dronabinol enhancement of appetite in cancer patients. Recent clinical experience with dronabinol. (abst - 1990)
(abst - 1991)

(abst - 1992)

(abst - 1992) (abst - 1993)
Treatment of spasticity in spinal cord injury with dronabinol, a tetrahydrocannabinol derivative. (abst - 1995)
Effects of dronabinol on anorexia and disturbed behavior in patients with Alzheimer's disease (abst - 1997)
Intractable nausea and vomiting due to gastrointestinal mucosal metastases relieved by tetrahydrocannabinol (dronabinol). (abst - 1997)
Abuse potential of dronabinol (Marinol).

(abst 1998)
270
Preliminary observation with dronabinol in patients with intractable pruritus secondary to cholestatic liver disease. (abst - 2002)
Cannabis and the brain.
(full - 2003) http://brain.oxfordjournals.org/cgi/content/full/126/6/1252 (abst - 2003)
Cannabinoid rotation in a young woman with chronic cystitis

Safety and efficacy of dronabinol in the treatment of agitation in patients with Alzheimers disease A retrospective chart review (abst - 2003)
On the application of cannabis in paediatrics and epileptology.

(abst - 2003)
Open-label study of dronabinol in the treatment of refractory agitation in Alzheimers disease: a pilot study (abst - 2003)

(abst - 2003)
MARINOL (Dronabinol) Capsules
(monograph - 2004)
http://www.fda.gov/ohrms/dockets/dockets/05n0479/05N-0479-emc0004-04.pdf
Does the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double blind placebo controlled crossover trial (full - 2004)
http://www.bmj.com/cgi/content/full/329/7460/253
A Novel Intervention for the Treatment of Gout in an Elderly Rehabilitation Patient in Whom Conventional Treatment was Ineffective (full 2004)
http://www.medicine.virginia.edu/clinical/departments/physical-medicine-rehabilitation/Gout-page
Cannabinoid agonists in the treatment of blepharospasm--a case report study. (abst - 2004) http://www.ncbi.nlm.nih.gov/pubmed/15159681 US Patent Application 20060160888 - Room-temperature stable dronabinol formulations (full 2006) http://www.patentstorm.us/applications/20060160888/fulltext.html Dronabinol reduces signs and symptoms of idiopathic intracranial hypertension : a case report (abst + 1st page - 2006) http://www.liebertonline.com/doi/abs/10.1089/jop.2006.22.68 Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases. (abst - 2006)
271
Effect of a cannabinoid agonist on gastrointestinal transit and postprandial satiation in healthy human subjects: a randomized, placebo-controlled study (abst - 2006)
ACG: Cannabinoid Activator Mellows Out Colon

http://www.medpagetoday.com/MeetingCoverage/ACG/tb/4410
(news - 2006) (news 2006)
Cannabis Chemicals May Alleviate Post-Eating Stomach Cramps
http://www.bio-medicine.org/medicine-news/Cannabis-Chemicals-May-Alleviate-Post-Eating-StomachCramps-15219-1/
Effects of a cannabinoid receptor agonist on colonic motor and sensory functions in humans: a randomized, placebo-controlled study (full - 2007)
http://ajpgi.physiology.org/cgi/content/full/293/1/G137
US Patent Application 20070020193 - Dronabinol compositions and methods for using same (full 2007) http://www.patentstorm.us/applications/20070020193/fulltext.html Dronabinol an effective appetite stimulant? A pilot study (abst - 2007)
Cannabinoids in the treatment of chemotherapy-induced nausea and vomiting: beyond prevention of acute emesis. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17566383 Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep. (abst - 2007) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=190 Dronabinol and retinal hemodynamics in humans. (abst - 2007)
Symptomatic treatment of multiple sclerosis using cannabinoids: recent advances. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17868014 Dronabinol and marijuana in HIV-positive marijuana smokers. Caloric intake, mood, and sleep. (abst - 2007) http://marijuana.researchtoday.net/archive/4/8/1234.htm Efficacy of dronabinol alone and in combination with ondansetron versus ondansetron alone for delayed chemotherapy-induced nausea and vomiting. (abst - 2007)
Cannabinoids in the management of difficult to treat pain
(full - 2008)
Current Status of Cannabis Treatment of Multiple Sclerosis with an Illustrative Case Presentation of a Patient with MS, Complex Vocal Tics, Paroxysmal Dystonia, and Marijuana Dependence Treated with Dronabinol. (full - 2008)
http://medicalcannabis.com/images/pdf09/indications/ms/deutsch_et_al_2008.pdf
272
US Patent Application 20080112895 - Aqueous dronabinol formulations

(full 2008)
Improvement in Refractory Obsessive Compulsive Disorder With Dronabinol (letter- 2008) http://ajp.psychiatryonline.org/cgi/content/full/165/4/536 Emerging strategies for exploiting cannabinoid receptor agonists as medicines. (full 2009)
Cluster attacks responsive to recreational cannabis and dronabinol.

(abst - 2009)
Effects of {Delta}9-tetrahydrocannabinol on reward and anxiety in rats exposed to chronic unpredictable stress (abst - 2009)
Synthetic delta-9-tetrahydrocannabinol (dronabinol) can improve the symptoms of schizophrenia. (abst - 2009)
The FDA has written documentation that patients can overdose on Marinol and that it can be lethal (news - 2009)
http://www.examiner.com/examiner/x-19678-Cannabis-Revolution-Examiner~y2009m10d23-The-FDAhas-written-documentation-that-patients-can-overdose-on-Marinol-and-that-it-can-be-lethal
Use of dronabinol (delta-9-THC) in autism: A prospective single-case-study with an early infantile autistic child (full 2010) http://www.cannabis-med.org/data/pdf/en_2010_04_1.pdf Delta9-tetrahydrocannabivarin testing may not have the sensitivity to detect marijuana use among individuals ingesting dronabinol. (full - 2010)
Effect of dronabinol on central neuropathic pain after spinal cord injury: a pilot study. (abst 2010) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=313 Efficacy and tolerability of high-dose dronabinol maintenance in HIV-positive marijuana smokers: a controlled laboratory study. (abst 2010)
Dronabinol, a cannabinoid agonist, reduces hair pulling in trichotillomania: a pilot study. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21590520/abstract/Dronabinol_a_cannabinoid_ago nist_reduces_hair_pulling_in_trichotillomania:_a_pilot_study_
(abst 2011)
273
Pharmacogenetic Trial of a Cannabinoid Agonist Shows Reduced Fasting Colonic Motility in Patients with Non-Constipated Irritable Bowel Syndrome. (abst 2011)
Drunk versus drugged: How different are the drivers?

(abst 2011)
Dronabinol for the treatment of cannabis dependence: a randomized, double-blind, placebo-controlled trial. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21310551/abstract/Dronabinol_for_the_treatment_ of_cannabis_dependence:_a_randomized_double_blind_placebo_controlled_trial_
Science: THC effective in trichotillomania symptoms in a pilot study
(news 2011)
DRUG INTERACTIONS - see INTERACTIONS WITH OTHER DRUGS
DRUG TESTING Legal and ethical aspects of drug testing. (full - 1989)
Interference of Common Household Chemicals in Immunoassay Methods for Drugs of Abuse (full - 1989)
http://www.clinchem.org/cgi/reprint/35/4/648?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cann abinoid&searchid=1&FIRSTINDEX=1440&resourcetype=HWCIT
Passive inhalation of cannabis smoke: a novel defence strategy?

(abst - 1996)
GC-MS analysis of the total delta9-THC content of both drug- and fiber-type cannabis seeds. (abst 2000)
http://www.ncbi.nlm.nih.gov/sites/entrez/11110027?dopt=Abstract&holding=f1000,f1000m,isrctn
Consumption and quantitation of delta9-tetrahydrocannabinol in commercially available hemp seed oil products. (abst 2000) http://www.ncbi.nlm.nih.gov/pubmed/11043660 Toxicological Screening for Drugs of Abuse in Samples Adulterated with Household Chemicals. (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/12197198
274
Practical Challenges to Positive Drug Tests for Marijuana

http://www.clinchem.org/cgi/content/full/49/7/1037
(editorial - 2003) (full - 2004)
A Review of Internet-Based Home Drug-Testing Products for Parents
http://pediatrics.aappublications.org/cgi/content/full/113/4/720?maxtoshow=&hits=80&RESULTFORMA T=&fulltext=cannabis&searchid=1&FIRSTINDEX=1920&resourcetype=HWCIT
Drug testing in the workplace
(full - 2004) (abst 2004)
http://www.ukcia.org/research/DrugTestingInWorkplace.pdf
Passive Inhalation of Cannabis Smoke.

Drugs of Abuse: Analyses and Ingested Agents That Can Induce Interference or CrossReactivity (full - 2006)
http://labmed.ascpjournals.org/content/37/6/358.full.pdf+html?maxtoshow=&hits=80&RESULTFORMAT =&fulltext=cannabinoid&searchid=1&FIRSTINDEX=2400&resourcetype=HWCIT
Review of biologic matrices (urine, blood, hair) as indicators of recent or ongoing cannabis use. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16628124 The Effects of Adulterants and Selected Ingested Compounds on Drugs-of-Abuse Testing in Urine (full - 2007) http://ajcp.ascpjournals.org/content/128/3/491.full.pdf+html Human Cannabinoid Pharmacokinetics (full - 2007) (full 2007)
Roadside sobriety tests and attitudes toward a regulated cannabis market.

Urine drug test interpretation: what do physicians know?

(abst - 2007) (abst - 2007)
Toxicity From the Use of Niacin to Beat Urine Drug Screening

Misusing Vitamin To Foil Drug Test May Be Toxic; Plus, It Doesn't Work (news - 2007) http://www.sciencedaily.com/releases/2007/04/070410162457.htm Biomarkers for the effects of cannabis and THC in healthy volunteers
(full - 2008)
Drug-Test Cheats Try New Tricks on Labs
(news - 2008)
http://www.webmd.com/mental-health/news/20080728/drug-test-cheats-try-new-tricks-on-labs
Reintoxication: the release of fat-stored Delta-tetrahydrocannabinol (THC) into blood is enhanced by food deprivation or ACTH exposure. (full - 2009)
275
Passive inhalation of cannabis smoke--is it detectable?

(abst - 2009) (abst 2010)
Testing for cannabis in the work-place: a review of the evidence.

Just Say No to Drug Tests Then Bargain
(news - 2010)
http://labornotes.org/2010/02/just-say-no-drug-tests-then-bargain
Has the Most Common Marijuana Test Resulted in Tens of Thousands of Wrongful Convictions? (news 2010)
http://www.alternet.org/investigations/147613/has_the_most_common_marijuana_test_resulted_in_tens_of _thousands_of_wrongful_convictions/?page=entire
APA: Drug Test Results Often Flawed
(news - 2010)
http://www.medpagetoday.com/MeetingCoverage/APA/20253
Postmortem redistribution of 9-tetrahydrocannabinol (THC), 11-hydroxy-THC (11-OHTHC), and 11-nor-9-carboxy-THC (THCCOOH). (abst 2011)
A preliminary investigation on the distribution of cannabinoids in man.
(abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21570784/abstract/A_preliminary_investigation_o n_the_distribution_of_cannabinoids_in_man_
Use of high-resolution accurate mass spectrometry to detect reported and previously unreported cannabinomimetics in "herbal high" products. (abst 2011)
Simultaneous determination of delta-9-tetrahydrocannabinol cannabidiol and cannabinol in edible oil using ultra performance liquid chromatography-tandem mass spectrometry (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21381415/abstract/%5BSimultaneous_determinati on_of_delta_9_tetrahydrocannabinol_cannabidiol_and_cannabinol_in_edible_oil_using_ultra_performance _liquid_chromatography_tandem_mass_spectrometry%5D_
Cannabinoids in postmortem toxicology.

(abst 2011)
Immunochemical approach using monoclonal antibody against (9)tetrahydrocannabinolic acid (THCA) to discern cannabis plants and to investigate new drug candidates. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21143135/abstract/Immunochemical_approach_usi ng_monoclonal_antibody_against_%CE%94_9__tetrahydrocannabinolic_acid__THCA__to_discern_canna bis_plants_and_to_investigate_new_drug_candidates_
New tests for 'legal marijuana,' 'bath salts' and other emerging designer drugs (news 2011) http://www.physorg.com/news/2011-08-legal-marijuana-salts-emerging-drugs.html
276
DRUG TESTING - BLOOD Delta-9-tetrahydrocannabinol: Metabolism and Disposition in Long-term Marihuana Smokers. (abst 1971)
http://medical-journals.healia.com/doc/5087483/Delta-9-tetrahydrocannabinol-metabolism-and-dispositionin-long-term-marihuana-smokers
Stability of delta 9-tetrahydrocannabinol (THC), 11-hydroxy-THC, and 11-nor-9carboxy-THC in blood and plasma. (abst 1984) http://www.ncbi.nlm.nih.gov/pubmed/6094914 Tetrahydrocannabinol stability in whole blood: plastic versus glass containers. (abst 1986) http://www.ncbi.nlm.nih.gov/pubmed/3018361 Serum cannabinoid levels 24 to 48 hours after cannabis smoking
(abst 2003)
Estimating the Time of Last Cannabis Use from Plasma {Delta}9-Tetrahydrocannabinol and 11-nor-9-Carboxy-{Delta}9-Tetrahydrocannabinol Concentrations (full - 2005)
Driving under the influence of cannabis: a 10-year study of age and gender differences in the concentrations of tetrahydrocannabinol in blood. (abst - 2008)
Cannabinoid concentrations in spot serum samples 24-48 hours after discontinuation of cannabis smoking. (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/18334100 Simultaneous analysis of THC and its metabolites in blood using liquid chromatographytandem mass spectrometry. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18922747 Do Delta(9)-tetrahydrocannabinol concentrations indicate recent use in chronic cannabis users? (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784185/?tool=pmcentrez A semi-automated solid-phase extraction liquid chromatography/tandem mass spectrometry method for the analysis of tetrahydrocannabinol and metabolites in whole blood. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19630026/abstract/A_semi_automated_solid_phas e_extraction_liquid_chromatography/tandem_mass_spectrometry_method_for_the_analysis_of_tetrahydro cannabinol_and_metabolites_in_whole_blood_
Identification of Recent Cannabis Use:Whole-Blood and Plasma Free and Glucuronidated Cannabinoid Pharmacokinetics Following Controlled Smoked Cannabis Administration. (abst 2009) http://www.ncbi.nlm.nih.gov/pubmed/21836075
277
Quantitation of Total 11-Nor-9-Carboxy-Delta 9-Tetrahydrocannabinol in Urine and Blood Using Gas Chromatography-Mass Spectrometry (GC-MS). (abst - 2010)
Concentrations of delta9-tetrahydrocannabinol and 11-nor-9carboxytetrahydrocannabinol in blood and urine after passive exposure to Cannabis smoke in a coffee shop. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20465865 Interpretation of blood analysis data found after passive exposure to cannabis (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20506708/abstract/%5BInterpretation_of_blood_a nalysis_data_found_after_passive_exposure_to_cannabis%5D_

(abst 2010)
Oral Fluid and Plasma Cannabinoid Ratios after Around-the-Clock Controlled Oral {Delta}9-Tetrahydrocannabinol Administration. (abst 2011)
Identification of Recent Cannabis Use:Whole-Blood and Plasma Free and Glucuronidated Cannabinoid Pharmacokinetics Following Controlled Smoked Cannabis Administration. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21836075 Oral Fluid and Plasma Cannabinoid Ratios after Around-the-Clock Controlled Oral {Delta}9-Tetrahydrocannabinol Administration. (abst 2011)
Influence of ethanol on cannabinoid pharmacokinetic parameters in chronic users. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21116612 Plasma cannabinoid pharmacokinetics following controlled oral delta9tetrahydrocannabinol and oromucosal cannabis extract administration. (abst 2011)
Variability of cannabinoid findings in blood

(abst 2011) (news 2011)
Latest blood test detects 12 popular synthetic cannabinoids in "fake pot".
http://www.thefreelibrary.com/Latest+blood+test+detects+12+popular+synthetic+cannabinoids+in+%22fa ke...-a0261876557
Colorados 5ng/ml per se DUID bill dies again as new research backs higher thresholds for regular users (news 2011)
http://stash.norml.org/colorados-5ngml-per-se-duid-bill-dies-again-as-new-research-backs-higherthresholds-for-regular-users
278
DRUG TESTING BREATH TEST Detection of (9)-tetrahydrocannabinol in exhaled breath collected from cannabis users. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22004672
DRUG TESTING - HAIR Testing human hair for cannabis (abst - 1995) (abst 1998) (abst - 1999)
Drugs in Prehistory: Chemical Analysis of Ancient Human Hair.

http://www.fsijournal.org/article/S0379-0738%2899%2900204-2/abstract
Are cannabinoids detected in hair after washing with Cannabio shampoo?
http://www.ncbi.nlm.nih.gov/pubmed/10488922?ordinalpos=101&itool=EntrezSystem2.PEntrez.Pubmed.P ubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Stability of Cannabinoids in Hair Samples Exposed to Sunlight
(full - 2000)
http://www.clinchem.org/cgi/content/full/46/11/1846?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabinoid&searchid=1&FIRSTINDEX=880&resourcetype=HWCIT
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1721515/pdf/v088p00F98.pdf/?tool=pmcentrez
Weather-induced changes in cannabinoid content of hair
(abst - 2003)
Assessing the potential of a "color effect" for hair analysis of 11-nor-9-carboxy-delta(9)tetrahydrocannabinol: analysis of a large sample of hair specimens. (abst 2003)
Cannabinoids in hair: strategy to prove marijuana/hashish consumption
(abst - 2004)
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T6W-4CVV8RB1&_user=10&_origUdi=B6X0P-4XMKB9S4&_fmt=high&_coverDate=10%2F29%2F2004&_rdoc=1&_orig=article&_acct=C000050221&_version= 1&_urlVersion=0&_userid=10&md5=ad356393e1039ca52b02f10f1f55a794
Deposition of cannabinoids in hair after long-term use of cannabis

(abst - 2006)
279
Cannabinoid concentrations in hair from documented cannabis users.

(full - 2007)
Differentiation between drug use and environmental contamination when testing for drugs in hair (abst - 2007)
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T6W-4R2GRYJ1&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlV ersion=0&_userid=10&md5=03a3594850e79c7c2dad1bd10fb041bf
Evaluation of the IDS One-Step ELISA kits for the detection of illicit drugs in hair (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17628371 Hair analysis for Delta9-tetrahydrocannabinolic acid A--new insights into the mechanism of drug incorporation of cannabinoids into hair. (abst - 2010)
11-nor-Delta9-tetrahydrocannabinol-9-carboxylic acid ethyl ester (THC-COOEt): unsuccessful search for a marker of combined cannabis and alcohol consumption. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20074877/abstract/11_nor_Delta9_tetrahydrocanna binol_9_carboxylic_acid_ethyl_ester__THC_COOEt_:_unsuccessful_search_for_a_marker_of_combined_ cannabis_and_alcohol_consumption_
A study on the concentrations of 11-nor-(9)-tetrahydrocannabinol-9-carboxylic acid (THCCOOH) in hair root and whole hair. (abst 2011)
A comparative study on the concentrations of 11-nor-(9)-tetrahydrocannabinol-9carboxylic acid (THCCOOH) in head and pubic hair. (abst 2011)
Detection and quantification of 11-nor-9-tetrahydrocannabinol-9-carboxylic acid in hair by GC/MS/MS in Negative Chemical Ionization mode (NCI) with a simple and rapid liquid/liquid extraction (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/22036308/abstract/Detection_and_quantification_o f_11_nor_%CE%949_tetrahydrocannabinol_9_carboxylic_acid_in_hair_by_GC/MS/MS_in_Negative_Che mical_Ionization_mode__NCI__with_a_simple_and_rapid_liquid/liquid_extraction_
The standardization of results on hair testing for drugs of abuse: An interlaboratory exercise in Lombardy Region, Italy. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/22018743/abstract/The_standardization_of_results _on_hair_testing_for_drugs_of_abuse:_An_interlaboratory_exercise_in_Lombardy_Region_Italy_
280
DRUG TESTING - OTHER Nail Analysis for Drugs of Abuse: Extraction and Determination of Cannabis in Fingernails by Ria and Gc-ms. (full 1999)
http://docstore.ingenta.com/cgibin/ds_deliver/1/u/d/ISIS/66686566.1/pres/jat/1999/00000023/00000003/art00003/2AC5C11351BA9FDF1 326514445561BD47516919757.pdf?link=http://www.ingentaconnect.com/error/delivery&format=pdf
Wiping Up the Evidence
(news - 2000)
http://www.webmd.com/news/20000626/wiping-up-drug-evidence
Prevalence of Illicit Drug Use in Plasmapheresis Donors.
(abst 2003) (full - 2004) (full - 2006)
Usefulness of Sweat Testing for the Detection of Cannabis Smoke


Prevalence of gestational exposure to cannabis in a Mediterranean city by meconium analysis. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17953730 Excretion of 9-tetrahydrocannabinol in sweat (full - 2008) (abst 2010)
Drugs of abuse in airborne particulates in urban environments.
http://www.unboundmedicine.com/medline/ebm/record/20447692/abstract/Drugs_of_abuse_in_airborne_p articulates_in_urban_environments_
Versatile new ion source for the analysis of materials in open air under ambient conditions. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/20655111/abstract/Evaluation_of_drugs_of_abuse _use_and_trends_in_a_prison_through_wastewater_analysis_
DRUG TESTING - ORAL Passive cannabis smoke exposure and oral fluid testing. II. Two studies of extreme cannabis smoke exposure in a motor vehicle. (abst 2005)
281
Drug Testing in Oral Fluid
(full - 2006)
Oral fluid testing for cannabis: on-site OraLine IV s.a.t. device versus GC/MS. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16854544 Correlation of Delta9-tetrahydrocannabinol concentrations determined by LC-MS-MS in oral fluid and plasma from impaired drivers and evaluation of the on-site Drger DrugTest. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16842950 Interpretation of Oral Fluid Tests for Drugs of Abuse (full - 2007)
Roadside oral fluid testing: Comparison of the results of Drugwipe tests with laboratory (abst - 2008) http://marijuana.researchtoday.net/archive/5/3/1351.htm Portable Oral-Fluid Tests Still Unreliable For Pot, Study Says
(news - 2008)
Evaluation of on-site oral fluid screening using Drugwipe-5(+(R)), RapidSTAT((R)) and Drug Test 5000((R)) for the detection of drugs of abuse in drivers. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19913376/full_citation/Evaluation_of_on_site_oral _fluid_screening_using_Drugwipe_5_+_R___RapidSTAT__R___and_Drug_Test_5000__R___for_the_det ection_of_drugs_of_abuse_in_drivers_
Analysis of cannabis in oral fluid specimens by GC-MS with automatic SPE. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/20120601 Method For Detecting 23 Drugs And Medicines In Saliva Developed
(news - 2009)
Patent 7816143 Oral detection test for cannabinoid use

(full -2010)
Simultaneous quantification of cannabinoids and metabolites in oral fluid by twodimensional gas chromatography mass spectrometry. (abst - 2010)
Direct detection of Delta9-tetrahydrocannabinol in saliva using a novel homogeneous competitive immunoassay with fluorescence quenching. (abst - 2010)
US Patent Application 20110020945 - ORAL DETECTION TEST FOR CANNABINOID USE (full 2011)
Cannabinoids in oral fluid following passive exposure to marijuana smoke. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21763088
282
Oral Fluid Cannabinoids in Chronic, Daily Cannabis Smokers During Sustained, Monitored Abstinence. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21677094 A validated method for the detection and quantitation of 50 drugs of abuse and medicinal drugs in oral fluid by gas chromatography-mass spectrometry. (abst 2011)
Cannabinoids and metabolites in expectorated oral fluid after 8 days of controlled around-the-clock oral THC administration. (abst - 2011)
Oral Fluid and Plasma Cannabinoid Ratios after Around-the-Clock Controlled Oral {Delta}9-Tetrahydrocannabinol Administration. (abst 2011)
(abst 2011)
DRUG TESTING - URINE Delta-9-tetrahydrocannabinol: Metabolism and Disposition in Long-term Marihuana Smokers. (abst 1971)
http://medical-journals.healia.com/doc/5087483/Delta-9-tetrahydrocannabinol-metabolism-and-dispositionin-long-term-marihuana-smokers
Confirmation of the Presence of 11-Hydroxy-r 9-Tetrahydrocannabinol in the Urine of Marijuana Smokers (full - 1972)
http://ajph.aphapublications.org/cgi/reprint/62/10/1394?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=cannabis&searchid=1&FIRSTINDEX=3760&resourcetype=HWCIT
Detection of cannabis products in urine by radioimmunoassay. Homogeneous enzyme immunoassay for cannabinoids in urine.
http://www.clinchem.org/cgi/reprint/24/1/95
(full -1975) (full - 1978) (abst - 1981) (abst 1982)
Laboratory verification of heavy and light users of cannabis

Persistence of Urinary Marijuana Levels After Supervised Abstinence.
http://medical-journals.healia.com/doc/6287871/Persistence-of-urinary-marijuana-levels-after-supervisedabstinence
283
Passive inhalation of marihuana smoke and urinary excretion of cannabinoids (abst - 1983) http://www.nature.com/clpt/journal/v34/n1/abs/clpt1983125a.html Marijuana-Laced Brownies: Behavioral Effects, Physiologic Effects, and Urinalysis in Humans Following Ingestion (full 1988)
http://docstore.ingenta.com/cgibin/ds_deliver/1/u/d/ISIS/66725041.1/pres/jat/1988/00000012/00000004/art00001/326C346C81BA765A1 326770337BF166BCAB593B4E5.pdf?link=http://www.ingentaconnect.com/error/delivery&format=pdf
Passive Inhalation of Cannabis Smoke.

(abst 2004)
Excretion patterns of cannabinoid metabolites after last use in a group of chronic users (full - 1985) http://www.nature.com/clpt/journal/v38/n5/pdf/clpt1985226a.pdf Contact highs and urinary cannabinoid excretion after passive exposure to marijuana smoke (full - 1986) http://www.nature.com/clpt/journal/v40/n3/pdf/clpt1986171a.pdf Cannabinoid intake by passive smoking (abst - 1987)
Cross-reactivity of selected compounds in the Abbott TDx cannabinoid assay. (full 1990)
http://docstore.ingenta.com/cgibin/ds_deliver/1/u/d/ISIS/66605954.1/pres/jat/1990/00000014/00000005/art00003/2C614027ADDC04511 3261723636BEC72FF8764DCD1.pdf?link=http://www.ingentaconnect.com/error/delivery&format=pdf
Urinalysis and Casual Handling of Marijuana and Cocaine
(full 1991)
http://docstore.ingenta.com/cgibin/ds_deliver/1/u/d/ISIS/66605938.1/pres/jat/1991/00000015/00000001/art00012/187C12CCE78236AD1 326172203D304C71EDE83B642.pdf?link=http://www.ingentaconnect.com/error/delivery&format=pdf
High urinary cannabinoids from a hashish body packer.

(abst 1993)
Increased detection of marijuana use with a 50 micrograms/L urine screening cutoff. (full - 1994) http://www.clinchem.org/cgi/reprint/40/11/2114 Hemp oil ingestion causes positive urine tests for 9-tetrahydrocannabinol carboxylic acid (full - 1997)
http://www.druglibrary.org/crl/drugtesting/Constantino%20et.al%2097%20Hemp%20Oil%20JAnToxicol.p df
A procedure to overcome interferences caused by the adulterant "Klear" in the GC-MS analysis of 11-nor-delta9-THC-9-COOH. (full 1997)
http://docstore.ingenta.com/cgibin/ds_deliver/1/u/d/ISIS/66605696.1/pres/jat/1997/00000021/00000003/art00014/5D767445E9634557132 6170724C29AEA643DCA3F47.pdf?link=http://www.ingentaconnect.com/error/delivery&format=pdf
284
Excretion of Cannabinoids in Urine After Ingestion of Cannabis Seed Oil.
(abst 1997)
http://medical-journals.healia.com/doc/9288590/Excretion-of-cannabinoids-in-urine-after-ingestion-ofcannabis-seed-oil
Marijuana-positive urine test results from consumption of hemp seeds in food products. (abst 1997) http://www.ncbi.nlm.nih.gov/pubmed/9323528 Urinary excretion profiles of 11-nor-9-carboxy-delta9-tetrahydrocannabinol: a delta9THCCOOH to creatinine ratio study. (abst 1999)
Adulteration of urine by "Urine Luck".

(full 1999)
Potassium nitrite reaction with 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid in urine in relation to the drug screening analysis (abst - 1999)
http://www.ncbi.nlm.nih.gov/pubmed/10486947?ordinalpos=102&itool=EntrezSystem2.PEntrez.Pubmed.P ubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Concentration of Marijuana Metabolites in the Urine After Ingestion of Hemp Seed Tea. (abst - 1999)
http://medical-journals.healia.com/doc/10390703/Concentration-of-marijuana-metabolites-in-the-urineafter-ingestion-of-hemp-seed-tea
Cannabinoid mimics in chocolate utilized as an argument in court

http://chocolate.org/chocdefence.html
(abst 2000)
Evaluating the impact of hemp food consumption on workplace drug tests. (abst 2001) http://www.ncbi.nlm.nih.gov/pubmed/11765026 Delta9-tetrahydrocannabivarin as a marker for the ingestion of marijuana versus Marinol: results of a clinical study (abst - 2001)
Effects of oxidizing adulterants on detection of 11-nor-delta9-THC-9-carboxylic acid in urine. (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/12423000 Monitoring urinary excretion of cannabinoids by fluorescence-polarization immunoassay: a cannabinoid-to-creatinine ratio study. (abst 2002)
Urinary Cannabinoid Detection Times after Controlled Oral Administration of {Delta}9Tetrahydrocannabinol to Humans (full - 2003)
Papain: a novel urine adulterant. (abst 2005)
285
Urinary excretion profiles of 11-nor-9-carboxy-Delta9-tetrahydrocannabinol: a Delta9THC-COOH to creatinine ratio study #2. (abst 2003)
Urinary excretion profiles of 11-nor-9-carboxy-Delta9-tetrahydrocannabinol. Study III. A Delta9-THC-COOH to creatinine ratio study. (abst 2003)
Urinary excretion profiles of 11-nor-9-carboxy-delta9-tetrahydrocannabinol and 11hydroxy-delta9-THC: cannabinoid metabolites to creatinine ratio study IV. (abst 2004)
Detection time of regular THC use in urine shorter than often assumed
(abst - 2006)
The effects of adulterants and selected ingested compounds on drugs-of-abuse testing in urine. (full - 2007) http://ajcp.ascpjournals.org/content/128/3/491.long Simultaneous GCEI-MS Determination of 9-Tetrahydrocannabinol, 11-Hydroxy-9Tetrahydrocannabinol, and 11-nor-9-Carboxy-9-Tetrahydrocannabinol in Human Urine Following Tandem Enzyme-Alkaline Hydrolysis (full - 2007)
Urine drug test interpretation: what do physicians know?

(abst - 2007) (abst - 2007) (abst - 2007)
Family physicians' proficiency in urine drug test interpretation.

Toxicity From the Use of Niacin to Beat Urine Drug Screening

http://www.ncbi.nlm.nih.gov/pubmed/17418450?log$=activity
Urine Drug Screening: Practical Guide for Clinicians
(full - 2008)
http://mayoclinproc.highwire.org/content/83/1/66.full?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabinoid&searchid=1&FIRSTINDEX=1520&resourcetype=HWCIT
Urinary elimination of 11-nor-9-carboxy-delta9-tetrahydrocannnabinol in cannabis users during continuously monitored abstinence. (full - 2008)
Do Delta(9)-tetrahydrocannabinol concentrations indicate recent use in chronic cannabis users? (full - 2009)
Extended urinary Delta9-tetrahydrocannabinol excretion in chronic cannabis users precludes use as a biomarker of new drug exposure. (full - 2009)
286
Short communication: Urinary excretion of 11-nor-9-carboxy-Delta(9)tetrahydrocannabinol in a pregnant woman following heavy, chronic cannabis use. (letter - 2009)
http://www.unboundmedicine.com/medline/ebm/record/20040136/abstract/Short_communication:_Urinary _excretion_of_11_nor_9_carboxy_Delta_9__tetrahydrocannabinol_in_a_pregnant_woman_following_hea vy_chronic_cannabis_use_
Identifying New Cannabis Use with Urine Creatinine-Normalized THCCOOH Concentrations and Time Intervals Between Specimen Collections. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19470219/abstract/Identifying_New_Cannabis_Us e_with_Urine_Creatinine_Normalized_THCCOOH_Concentrations_and_Time_Intervals_Between_Speci men_Collections_
Urinary toxicological screening: Analytical interference between niflumic acid and cannabis. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19716686/abstract/%5BUrinary_toxicological_scre ening:_Analytical_interference_between_niflumic_acid_and_cannabis_%5D
Evaluation of a Human On-site Urine Multidrug Test for Emergency Use With Dogs (abst - 2009)
http://www.jaaha.org/cgi/content/abstract/45/2/59?maxtoshow=&hits=80&RESULTFORMAT=&fulltext= cannabis&searchid=1&FIRSTINDEX=3200&resourcetype=HWCIT
Passive inhalation of cannabis smoke--is it detectable?

(abst - 2009) (full 2010)
Urine Drug Screening: A Valuable Office Procedure

http://www.aafp.org/afp/2010/0301/p635.html
Delta9-tetrahydrocannabivarin testing may not have the sensitivity to detect marijuana use among individuals ingesting dronabinol. (full - 2010)

(abst 2010)
Quantitation of Total 11-Nor-9-Carboxy-Delta 9-Tetrahydrocannabinol in Urine and Blood Using Gas Chromatography-Mass Spectrometry (GC-MS). (abst - 2010)
Differentiating new cannabis use from residual urinary cannabinoid excretion in chronic, daily cannabis users. (abst - 2010)
http://www.unboundmedicine.com/medline/ebm/record/21134021/abstract/Differentiating_new_cannabis_ use_from_residual_urinary_cannabinoid_excretion_in_chronic_daily_cannabis_users_
Detection of cannabigerol and its presumptive metabolite in human urine after Cannabis consumption. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20614687
287
Screening for the synthetic cannabinoid JWH-018 and its major metabolites in human doping controls. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20872894 Now, There's a Test for That -- Norchem's "Fake Marijuana" Test Reveals Significantly Increased Abuse of Spice/K2 (news - 2010)
Liquid chromatography-tandem mass spectrometry analysis of urine specimens for K2 (JWH-018) metabolites. (full 2011)
http://docstore.ingenta.com/cgibin/ds_deliver/1/u/d/ISIS/66605491.1/pres/jat/2011/00000035/00000007/art00013/33697C59B13F9CFB13 26169859E74280D392B0112D.pdf?link=http://www.ingentaconnect.com/error/delivery&format=pdf
A method for CP 47, 497 a synthetic non-traditional cannabinoid in human urine using liquid chromatography tandem mass spectrometry. (abst 2011)
Zinc Reduces the Detection of Cocaine, Methamphetamine, and THC by ELISA Urine Testing. (abst 2011) We need 8 to 11 mg of zinc daily; over 40 mg/day can cause zinc poisoning.
Concentrations of delta9-tetrahydrocannabinol and 11-nor-9carboxytetrahydrocannabinol in blood and urine after passive exposure to Cannabis smoke in a coffee shop. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/20465865 Quantitative measurement of JWH-018 and JWH-073 metabolites excreted in human urine. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21506519 Differentiating new cannabis use from residual urinary cannabinoid excretion in chronic, daily cannabis users. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21134021 Efavirenz interference in urine screening immunoassays for tetrahydrocannabinol. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22067092
DYSKINESIA Beneficial and adverse effects of cannabidiol in a Parkinson patient with sinemet-induced dystonic dyskinesia. (abst - 1985)
The effects of the cannabinoid receptor agonist nabilone on L-DOPA induced dyskinesia in patients with idiopathic Parkinson's disease (PD). (abst - 1998)
288
Cannabinoids reduce levodopa-induced dyskinesia in Parkinson's disease: a pilot study. (abst - 2001) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=54 Cannabinoids reduce levodopa-induced dyskinesia in Parkinson's disease: a pilot study. (abst - 2001) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=54 Effects of pharmacological manipulations of cannabinoid receptors on severity of dystonia in a genetic model of paroxysmal dyskinesia. (abst 2002)
Tardive Dystonia and the Use of Cannabis.
(abst 2010)
Association study of Cannabinoid receptor 1 (CNR1) gene in tardive dyskinesia (abst - 2011) http://pharmgkb.org/pmid/21266946 The effects of cannabinoid drugs on abnormal involuntary movements in dyskinetic and non-dyskinetic 6-hydroxydopamine lesioned rats. (abst 2011)
DYSTONIA Tetrahydrocannabinol potentiates reserpine-induced hypokinesia. (abst 1981)

Treatment of Meige's syndrome with cannabidiol.
(abst - 1984) (full - 1986)

Cannabidiol (CBD) in dystonic movement disorders.
(abst - 1986)
(+)-WIN 55,212-2, a novel cannabinoid receptor agonist, exerts antidystonic effects in mutant dystonic hamsters. (abst - 1994) http://www.ncbi.nlm.nih.gov/pubmed/7698178
289
Cannabis in movement disorders. (abst - 1999) http://www.ncbi.nlm.nih.gov/pubmed/10627163 A Dramatic Response to Inhaled Cannabis in a Woman with Central Thalamic Pain and Dystonia (full - 2002) http://www.jpsmjournal.com/article/PIIS0885392402004268/fulltext Experiences with THC-treatment in children and adolescents
(abst - 2003)
Cannabinoid agonists in the treatment of blepharospasm--a case report study. (abst - 2004) http://www.ncbi.nlm.nih.gov/pubmed/15159681 Cannabis sativa and dystonia secondary to Wilson's disease. (needs free registration) (abst - 2005) http://www.medscape.com/medline/abstract/15390041 Current Status of Cannabis Treatment of Multiple Sclerosis with an Illustrative Case Presentation of a Patient with MS, Complex Vocal Tics, Paroxysmal Dystonia, and Marijuana Dependence Treated with Dronabinol. (full - 2008)
Tardive Dystonia and the Use of Cannabis
(letter - 2010)
http://www.turkpsikiyatri.com/en/default.aspx?modul=article&id=749
ECZEMA Hemp Supplement Boosts Body AND Mind Skin Complaint Man Grew Cannabis Want Nice Skin? Then Smoke Cannabis! Cannabis helps treat allergic reactions (anecdotal/news - 2001)
(news/ anecdotal- 2004) (news 2007) (news - 2007) (news 2007)
http://www.mapinc.org/drugnews/v04.n1222.a09.html
Cannabis compound reduces skin allergies in mice Cannabinoids Reduce Skin Inflammation
http://www.newscientist.com/article/dn12016-cannabis-compound-reduces-skin-allergies-in-mice.html
(news - 2007)
290
Marijuana Skin Cream? Hemp Seed Oil for Skin
(news - 2007) (news 2010) (anecdotal - 2010)
The Cannabis Closet: Severe Eczema
http://andrewsullivan.theatlantic.com/the_daily_dish/2010/05/the-cannabis-closet-severe-eczema.html
EDEMA ANTI-EDEMA AND ANALGESIC PROPERTIES OF 9TETRAHYDROCANNABINOL (THC) (abst- 1973)

Cannabinoid CB(2) receptor activation prevents bronchoconstriction and airway oedema in a model of gastro-oesophageal reflux. (abst - 2007)
EHLERS-DANLOS SYNDROME Ehlers-Danlos Syndrome (anecdotal/news- 2010)

http://andrewsullivan.theatlantic.com/the_daily_dish/2010/05/the-cannabis-closet-chronic-joint-pain.html
Schneider: Lansing mom says son's legal marijuana use unfairly stigmatized (anecdotal/news - 2010)
http://www.lansingstatejournal.com/article/20100628/NEWS01/6280333/1229/portland
ELMIRIC ACIDS - anandamide analogs The elmiric acids: biologically active anandamide analogs
(full - 2007) (full - 2007)
Potential anti-inflammatory actions of the elmiric (lipoamino) acids

291
ENCEPHALITIS CB2 receptors in the brain: role in central immune function

(full - 2007) (full - 2008)

ENCEPHALOMYELITIS/ EAE - a mouse multiple sclerosis model Suppression of experimental autoimmune encephalomyelitis by cannabinoids. (abst 1997) http://www.ncbi.nlm.nih.gov/pubmed/7852052 Immunoregulation of a viral model of multiple sclerosis using the synthetic cannabinoid R(+)WIN55,212 (full - 2003)
Cannabinoid-receptor 1 null mice are susceptible to neurofilament damage and caspase 3 activation. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/15953683 Experimental autoimmune encephalomyelitis disrupts endocannabinoid-mediated neuroprotection (full - 2006)
The endocannabinoid system is dysregulated in multiple sclerosis and in experimental autoimmune encephalomyelitis ( full - 2007)
http://brain.oxfordjournals.org/cgi/content/full/awm160v1
Control of Spasticity in a Multiple Sclerosis Model is mediated by CB1, not CB2, Cannabinoid Receptors (full - 2007)
292
A Cannabinoid CB2 receptor agonist attenuates experimental autoimmune encephalomyelitis (EAE) and reduces MOG-specific T cell proliferation (abst - 2007)
http://www.fasebj.org/cgi/content/meeting_abstract/21/6/A1393c?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=800& resourcetype=HWCIT
Cannabinoids in the management of spasticity associated with multiple sclerosis (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626929/?tool=pmcentrez Modulation of cannabinoid receptor activation as a neuroprotective strategy for EAE and stroke. (full 2009)
Administration of 2-arachidonoylglycerol ameliorates both acute and chronic Experimental Autoimmune Encephalomyelitis (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21406188/abstract/Administration_of_2_arachidon oylglycerol_ameliorates_both_acute_and_chronic_Experimental_Autoimmune_Encephalomyelitis_
ENDOCANNABINOIDS - also see ANANDAMIDE, 2-AG, Cannabinoids (encyclopedia entry)

http://www.chemie.de/lexikon/e/Cannabinoids/
Trick or treat from food endocannabinoids? (abst 1998)

Brain Chemicals Mimic Marijuana

(news - 1997) (news - 1998) (abst 1999)
Body's 'cannabis' could hold blood pressure key


UC Irvine Researchers Demonstrate How Marijuana-Like Chemicals Work In The Brain (news - 1999) http://www.sciencedaily.com/releases/1999/03/990323050735.htm
293
Enhanced levels of endogenous cannabinoids in the globus pallidus are associated with a reduction in movement in an animal model of Parkinsons disease (full - 2000)
Endocannabinoids control spasticity in a multiple sclerosis model
(full - 2000)
Sex steroid influence on cannabinoid CB(1) receptor mRNA and endocannabinoid levels in the anterior pituitary gland. (abst 2000) http://www.ncbi.nlm.nih.gov/pubmed/10733937 Cannabinoid CB1-receptor mediated regulation of gastrointestinal motility in mice in a model of intestinal inflammation (full - 2001)
The cannabinoids: an overview. Therapeutic implications in vomiting and nausea after cancer chemotherapy, in appetite promotion, in multiple sclerosis and in neuroprotection. (abst - 2001) http://www.ncbi.nlm.nih.gov/pubmed/11854768?dopt=Abstract Endocannabinoids are implicated in the infarct size-reducing effect conferred by heat stress preconditioning in isolated rat hearts. (full 2002)
http://cardiovascres.oxfordjournals.org/content/55/3/619.long
Never fear, cannabinoids are here
(article - 2002)
http://mcforadhd.free.fr/naturefear.pdf
Endocannabinoids in the central nervous system--an overview.

(abst - 2002)
Changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine. (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/12393235 Role of Endogenous Cannabinoids in Synaptic Signaling (full - 2003)
Endocannabinoids as mediators in the heart: a potential target for therapy of remodelling after myocardial infarction? (full - 2003)
Endocannabinoids protect the rat isolated heart against ischaemia (full - 2003)
Endocannabinoid signaling via cannabinoid receptor 1 is involved in ethanol preference and its age-dependent decline in mice (full - 2003)
294

http://brain.oxfordjournals.org/cgi/content/full/126/10/2191
(full - 2003) (full - 2003)
Endocannabinoids and the regulation of body fat: the smoke is clearing

Effect of maternal under-nutrition on pup body weight and hypothalamic endocannabinoid levels. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12678501 Possible endocannabinoid control of colorectal cancer growth.
(abst - 2003) (full - 2004)
Effects of Cannabis Therapy on Endogenous Cannabinoids

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Endocannabinoids and Their Implications for Epilepsy Endocannabinoids: Getting the message across
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(full - 2004)
Involvement of cannabinoid receptors in gut motility and visceral perception (full - 2004) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574910/?tool=pmcentrez Clinical Endocannabinoid Deficiency
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(full - 2004)
Harm reduction-the cannabis paradox
(full - 2005) (full - 2005)
http://www.harmreductionjournal.com/content/2/1/17

Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P (full - 2005)
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295
Body's Pot-Like Chemicals May Help Curb Pain
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Body's Own Marijuana-Like Compounds Are Crucial For Stress-Induced Pain Relief (news - 2005) http://www.sciencedaily.com/releases/2005/06/050628064435.htm Cream with endocannabinoids effective in the treatment of pruritus due to kidney disease (news - 2005) http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=207 Endocannabinoids -- The Brain's Cannabis -- Demonstrate Novel Modes Of Action To Stress (news - 2005) http://www.sciencedaily.com/releases/2005/07/050720065810.htm Multiple sclerosis may disrupt endocannabinoid brain protection mechanism (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1458835/?tool=pmcentrez Role of the Cannabinoid System in Pain Control and Therapeutic Implications for the Management of Acute and Chronic Pain Episodes (full - 2006)

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Endocannabinoids: Multi-scaled, Global Homeostatic Regulators of Cells and Society (abst - 2006) http://knowledgetoday.org/wiki/index.php/ICCS06/70 Endocannabinoids Mediate the Effects of Acute Stress and Corticosterone on Sex Behavior (full 2007) http://endo.endojournals.org/content/148/2/493.full Endocannabinoids and Related Compounds: Walking Back and Forth between Plant Natural Products and Animal Physiology (full - 2007)
Endocannabinoids block status epilepticus in cultured hippocampal neurons (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2617750/?tool=pmcentrez Endocannabinoids and the haematological system (full - 2007)
Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats (full - 2007)
296
Human Cannabinoid Pharmacokinetics
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Endocannabinoids as emerging suppressors of angiogenesis and tumor invasion (Review) (abst- link to full PDF 2007) http://www.spandidos-publications.com/or/17/4/813 Migraine may be related to under production of cannabinoids New Study Examines 'Brain's Own Marijuana' (news - 2007)
(news - 2007)
Non-redundant Functions of Cyclooxygenases: Oxygenation of Endocannabinoids (full 2008) http://www.jbc.org/content/283/13/8065.full Endocannabinoids and Liver Disease. III. Endocannabinoid effects on immune cells: implications for inflammatory liver diseases (full - 2008)

(full - 2008)
Cannabinoids in pancreatic cancer: Correlation with survival and pain

(full - 2008)
Endocannabinoids, blood pressure and the human heart. Inflammation and aging: can endocannabinoids help?
(full - 2008). (full - 2008) (full - 2008) (full - 2008)

Endocannabinoids in the retina: From marijuana to neuroprotection.


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Pain relief with cannabinoids-- the importance of endocannabinoids and cannabinoids for pain therapy (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18671173 Understanding the effects of endogenous cannabinoids (news - 2008) (news - 2008)

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Dynamic regulation of the endocannabinoid system: implications for analgesia (full - 2009) http://www.molecularpain.com/content/5/1/59 Cannabinoids, Endocannabinoids, and Related Analogs in Inflammation
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Endocannabinoids and Their Receptors as Targets for Obesity Therapy

(full - 2009)
Endocannabinoids and cardiovascular prevention: real progress? (abst - 2009)

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Phytocannabinoids and endocannabinoids.

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Pharmacological and therapeutic secrets of plant and brain (endo)cannabinoids. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/18777572 Endocannabinoid chemical biology: a tool for the development of novel therapies. (abst - 2009) http://www.unboundmedicine.com/medline/ebm/record/19457702/abstract/ Parasitic brain infection, endocannabinoids, and schizophrenia. (abst - 2009)
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The Endocannabinoid Anandamide: From Immunomodulation to Neuroprotection. Implications for Multiple Sclerosis (abst - 2009)
Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease. (abst 2009)
Endocannabinoids, Closely Related To Active Ingredients In Cannabis Plant, Can Promote Pain (news - 2009) http://www.sciencedaily.com/releases/2009/09/090911212404.htm Human Brains Make Their Own 'Marijuana' (news - 2009)
Enhanced Sweet Taste: Endocannabinoids Act Directly on Tongue Taste Receptors (news - 2009) http://www.sciencedaily.com/releases/2009/12/091222104920.htm R-Flurbiprofen Reduces Neuropathic Pain in Rodents by Restoring Endogenous Cannabinoids (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869361/ Endocannabinoids Are Expressed in Bone Marrow Stromal Niches and Play a Role in Interactions of Hematopoietic Stem and Progenitor Cells with the Bone Marrow Microenvironment (full 2010)
Endocannabinoids Prevent -Amyloid-mediated Lysosomal Destabilization in Cultured Neurons (abst 2010) http://www.jbc.org/content/285/49/38543.abstract Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood. (abst - 2010)
Endocannabinoids are expressed in bone marrow stromal niches and play a role in interactions of hematopoietic stem and progenitor cells with the bone marrow microenvironment (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20826813 Non-CB1, non-CB2 receptors for endocannabinoids, plant cannabinoids, and synthetic cannabimimetics: focus on G-protein-coupled receptors and transient receptor potential channels. (abst 2010)
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Gut feelings about the endocannabinoid system
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Endocannabinoids in liver disease.
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Acute Immobilization Stress Modulate GABA Release from Rat Olfactory Bulb: Involvement of EndocannabinoidsCannabinoids and Acute Stress Modulate GABA Release (full 2011) http://www.hindawi.com/journals/ijcb/2011/529851/ ENDOCANNABINOIDS AND TRAUMATIC BRAIN INJURY.
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Endocannabinoids and the cardiovascular response to stress.

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Targeting the Endocannabinod System to Limit Myocardial and Cerebral Ischemic and Reperfusion Injury. (abst 2011)
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CANNABINOIDS AND BONE: ENDOCANNABINOIDS MODULATE HUMAN OSTEOCLAST FUNCTION IN VITRO. (abst 2011)
Marijuana, endocannabinoids, and epilepsy: Potential and challenges for improved therapeutic intervention. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/22178327 Endocannabinoid Signaling In Dietary Restriction And Lifespan Extension (news 2011) http://www.medicalnewstoday.com/releases/225007.php Study helps explain why fatty foods are complicit in weight gain (news - 2011)
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Do Deficits in Brain Cannabinoids Contribute to Eating Disorders? (news 2011) http://www.sciencedaily.com/releases/2011/10/111031115226.htm

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ENDOCANNABINOID SYSTEM Cannabinoids (encyclopedia entry)

Cannabinoid Receptor Ligands Cellular effects of cannabinoids
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Cannabinoid Receptor Localization in Brain
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Loss of cannabinoid receptors in the substantia nigra in Huntington's disease. (abst 1993) http://www.ncbi.nlm.nih.gov/pubmed/8255419 Molecular characterization of a peripheral receptor for cannabinoids
(abst 1993)
REVIEW: Bioactive Amides of Fatty Acids Brain Chemicals Mimic Marijuana

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Changes in cannabinoid receptor binding and mRNA levels in several brain regions of aged rats. (abst 1998) http://www.ncbi.nlm.nih.gov/pubmed/9748581 Body's 'cannabis' could hold blood pressure key
(news - 1998) (full - 1999) (abst 1999)
Pain modulation by release of the endogenous cannabinoid anandamide


Molecular cloning of a human cannabinoid receptor which is also expressed in testis (abst 1991) http://pharmgkb.org/pmid/1718258 Finding of the endocannabinoid signalling system in Hydra, a very primitive organism: possible role in the feeding response. (abst 1999)
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Why your brain is primed for a high
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The Cannabinoid System and Cytokine Network Endocannabinoids and Vascular Function
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Cannabinoids, immune system and cytokine network.

Control by the endogenous cannabinoid system of ras oncogene-dependent tumor growth (full - 2001)
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The cannabinoids: an overview. Therapeutic implications in vomiting and nausea after cancer chemotherapy, in appetite promotion, in multiple sclerosis and in neuroprotection. (abst - 2001) http://www.ncbi.nlm.nih.gov/pubmed/11854768?dopt=Abstract How Marijuana Works Healing Haze? (news - 2001)
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Attack of the munchies
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Targeting the endocannabinoid system in cancer therapy: A call for further research (full - 2002) http://www.fuoriluogo.it/medicalcannabis/documenti/bifulco2002.pdf International Union of Pharmacology. XXVII. Classification of Cannabinoid Receptors (full 2002)
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Sourcing the Code: Searching for the Evolutionary Origins of Cannabinoid Receptors, Vanilloid Receptors, and Anandamide (full 2002)
Cannabinoid receptors and their ligands.

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Activation of cannabinoid receptors decreases the area of ischemic myocardial necrosis. (abst - 2002)
Cannabinoids and multiple sclerosis.

(abst - 2002)
The endogenous cannabinoid system controls extinction of aversive memories. (abst - 2002) http://www.ncbi.nlm.nih.gov/pubmed/12152079 Manipulation of the endocannabinoid system by a general anaesthetic.
(full 2003)
The Endocannabinoid System in Human Keratinocytes

(full 2003)
The cannabinoid system and immune modulation

http://www.jleukbio.org/content/74/4/486.full.pdf+html
(full 2003)
Endogenous cannabinoid system as a modulator of food intake.

(full - 2003)
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The cannabinoid system: a role in both the homeostatic and hedonic control of eating? (full 2003)
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The endocannabinoid system and Huntington's disease.

Effect of maternal under-nutrition on pup body weight and hypothalamic endocannabinoid levels. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12678501
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Clinical Endocannabinoid Deficiency

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The endocannabinoid system: a general view and latest additions

Effects of Cannabis Therapy on Endogenous Cannabinoids

http://www.cmcr.ucsd.edu/geninfo/piomelli_abs.htm
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The endogenous cannabinoid system protects against colonic inflammation (full - 2004) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC385396/?tool=pmcentrez The endocannabinoid system: physiology and pharmacology.
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Involvement of cannabinoid receptors in gut motility and visceral perception (full - 2004) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574910/?tool=pmcentrez Fibromyalgia, IBS, and the Endocannabinoid-CB-Receptor (ECBR) system (abst - 2004) http://www.prohealth.com//library/showArticle.cfm?libid=10562 The endocannabinoid system drives neural progenitor proliferation.
(full 2005)
Enhancing Cannabinoid Neurotransmission Augments the Extinction of Conditioned Fear (full - 2005) http://www.nature.com/npp/journal/v30/n3/full/1300655a.html Activation of the Peripheral Endocannabinoid System in Human Obesity (full - 2005)
Endocannabinoids and food intake: newborn suckling and appetite regulation in adulthood. (full - 2005) http://ebm.rsmjournals.com/cgi/content/full/230/4/225 Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptors (full - 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1430341/?tool=pmcentrez THE ENDOCANNABINOID SYSTEM: PHYSIOLOGY AND PHARMACOLOGY (full - 2005)
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(full - 2005)
304
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(abst 2005)
Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/16242629 The Endogenous Cannabinoid System. Therapeutic Implications for Neurologic and Psychiatric Disorders (abst 2005)
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New Antidepressant Drug Increases 'Brain's Own Cannabis'

(news - 2005)
Role of cannabinoid receptors in alcohol abuse

(news - 2005) (news - 2005)
Marijuana May Grow Neurons in the Brain

Increasing cannabinoid levels by pharmacological and genetic manipulation delay disease progression in SOD1 mice (full - 2006) http://www.fasebj.org/cgi/content/full/20/7/1003 Role of the Cannabinoid System in Pain Control and Therapeutic Implications for the Management of Acute and Chronic Pain Episodes (full - 2006)
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Cannabinoids and the Endocannabinoid System
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Cannabinoids biology: the search for new therapeutic targets.

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Activation of G-proteins in brain by endogenous and exogenous cannabinoids. (full 2006) http://www.ncbi.nlm.nih.gov/pubmed/16584117 Cannabinoid receptors and endocannabinoids: evidence for new players.
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The emerging role of the endocannabinoid system in endocrine regulation and energy balance. (full - 2006) http://edrv.endojournals.org/cgi/content/full/27/1/73 Experimental autoimmune encephalomyelitis disrupts endocannabinoid-mediated neuroprotection (full - 2006)
Neurophysiological, Neuroimmunological, and Neuroendocrine Basis of Pruritus (full - 2006) http://www.nature.com/jid/journal/v126/n8/full/5700231a.html The Endocannabinoid System as an Emerging Target of Pharmacotherapy (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241751/?tool=pmcentrez Not Too Excited? Thank Your Endocannabinoids Cannabinoids and the Endocannabinoid System (full - 2006) (full - 2006) (full - 2006)

The Endocannabinoid System Controls Key Epileptogenic Circuits in the Hippocampus (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769341/?tool=pmcentrez Cannabinoid receptors and endocannabinoids: evidence for new players. (full - 2006)
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Endocannabinoids in Chronic Migraine: CSF Findings Suggest a System Failure (full - 2006) http://www.nature.com/npp/journal/v32/n6/full/1301246a.html Frontiers in pruritus research: scratching the brain for more effective itch therapy (full 2006)
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Dysregulation of the Peripheral and Adipose Tissue Endocannabinoid System in Human Abdominal Obesity (full - 2006)
306
Endocannabinoids and the gastrointestinal tract.
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Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon (full - 2007)
Endocannabinoids block status epilepticus in cultured hippocampal neurons (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2617750/?tool=pmcentrez Activation of cannabinoid CB1 and CB2 receptors suppresses neuropathic nociception evoked by the chemotherapeutic agent vincristine in rats. (full 2007)
The psychoactive plant cannabinoid, Delta9-tetrahydrocannabinol, is antagonized by Delta8- and Delta9-tetrahydrocannabivarin in mice in vivo. (full - 2007)
Neuropharmacology of the endocannabinoid signaling system-molecular mechanisms, biological actions and synaptic plasticity. (full - 2007)
Downregulation of the CB1 Cannabinoid Receptor and Related Molecular Elements of the Endocannabinoid System in Epileptic Human Hippocampus (full - 2007)
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Neuropharmacology of the endocannabinoid signaling system-molecular mechanisms, biological actions and synaptic plasticity. (full - 2007)
The complications of promiscuity: endocannabinoid action and metabolism (full - 2007)

Expression and function of cannabinoid receptors CB1 and CB2 and their cognate cannabinoid ligands in murine embryonic stem cells. (full 2007)
Cannabinoids: A New Group of Agonists of PPARs
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Endocannabinoid metabolism and uptake: novel targets for neuropathic and inflammatory pain (full - 2007)
Endocannabinoids and the gastrointestinal tract: what are the key questions? (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190011/?tool=pmcentrez The endocannabinoid system is dysregulated in multiple sclerosis
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A possible role for the endocannabinoid system in the neurobiology of depression (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169225/?tool=pubmed The complications of promiscuity: endocannabinoid action and metabolism (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190010/?tool=pmcentrez Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234438/ The CB1 Cannabinoid Receptor Mediates Excitotoxicity-induced Neural Progenitor Proliferation and Neurogenesis (full - 2007) http://www.jbc.org/content/282/33/23892.full Modulation of Fear and Anxiety by the Endogenous Cannabinoid System
(full - 2007)

A possible role for the endocannabinoid system in the neurobiology of depression (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169225/?tool=pubmed Modulation of the endocannabinoid system: therapeutic potential against cocaine dependence. (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2134985/?tool=pubmed Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon. (full 2007)
Cannabis and Endocannabinoids: The Old Man and the Teenagers

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308
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Endocannabinoid metabolism and uptake: novel targets for neuropathic and inflammatory pain. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17704819?dopt=Abstract Cannabinoids and neuroprotection in motor-related disorders.
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Expression of cannabinoid receptors and neurotrophins in human gliomas.

(abst - 2007)
The endocannabinoid network: insight into the regulation of the neuroendocrine and metabolic systems. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17684453 Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-treated rats. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17396241 The importance of the endocannabinoid-system
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Endocannabinoids appear to play important role in regulating inflammation (news - 2007) http://www.news-medical.net/news/2007/06/08/26114.aspx Cannabinoid receptors in acute and chronic complications of atherosclerosis (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219535/?tool=pmcentrez Endocannabinoid Dysregulation in the Pancreas and Adipose Tissue of Mice Fed With a High-fat Diet (full - 2008) http://www.nature.com/oby/journal/v16/n3/full/oby2007106a.html Attenuation of Allergic Contact Dermatitis Through the Endocannabinoid System (full - 2008)
Multiple sclerosis, cannabinoids, and cognition.

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(full - 2008) (full 2008) (full - 2008)
Endocannabinoids and the Control of Energy Homeostasis Cannabinoid receptors and the regulation of bone mass Function of cannabinoids in heart failure
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Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis. (full - 2008)
The endocannabinoid system: an osteopathic perspective. (full - 2008)

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Modulation of the Endocannabinoid System in Cardiovascular Disease

(full - 2008)
Endocannabinoids in the Retina: From Marijuana to Neuroprotection (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584875/?tool=pubmed THE ENDOCANNABINOID SYSTEM AND CARDIOVASCULAR DISEASE Introduction (full - 2008)
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Endocannabinoid Dysregulation in the Pancreas and Adipose Tissue of Mice Fed With a High-fat Diet (full - 2008)
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The Medicinal Chemistry of Agents Targeting the Endogenous Cannabinoid System (editorial - 2008) http://www.benthamdirect.org/pages/b_viewarticle.php?articleID=3147248
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The endocannabinoid system in Huntington's disease.

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Expression of the endocannabinoid system in fibroblasts and myofascial tissues. (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/19083670 The role of the endocannabinoid system in Alzheimer's disease: facts and hypotheses. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18781980 Activation of the endocannabinoid system by organophosphorus nerve agents (abst - 2008) http://www.nature.com/nchembio/journal/v4/n6/abs/nchembio.86.html The endocannabinoid system: emotion, learning and addiction. (abst - 2008)
Immunomodulatory lipids in plants: plant fatty acid amides and the human endocannabinoid system. (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/18275004 ENDOCANNABINOIDS AND THE NEUROCHEMISTRY OF GLUTTONY. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18638022 Endogenous cannabinoids: structure and metabolism.
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Biology of endocannabinoid synthesis system.

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The endocannabinoid system and multiple sclerosis.

Cannabinoid receptors: where they are and what they do.

Dysregulation of the endocannabinoid system in obesity.

The role of endocannabinoid system in physiological and pathological processes in the eye (abst - 2008)
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Starting Point Of Sun-Induced Skin Cancer Discovered: Molecular 'Hooks' Also Pull Compounds From Marijuana From Bloodstream (news - 2008)

(full - 2009)
Effects of Cannabinoids on Caffeine Contractures in Slow and Fast Skeletal Muscle Fibers of the Frog (full - 2009)
Ulcerative Colitis Induces Changes on the Expression of the Endocannabinoid System in the Human Colonic Tissue (full - 2009)
Localisation and Function of the Endocannabinoid System in the Human Ovary (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640464/?tool=pmcentrez Cannabinoids: An emerging role in pain management? (full - 2009)
http://www.nursingcenter.com/library/JournalArticle.asp?Article_ID=863277
Dynamic regulation of the endocannabinoid system: implications for analgesia (full - 2009) http://www.molecularpain.com/content/5/1/59 Cannabinoids, Endocannabinoids, and Related Analogs in Inflammation (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664885/?tool=pubmed Biomarkers of Endocannabinoid System Activation in Severe Obesity (full - 2009)
The emerging role of the endocannabinoid system in cardiovascular disease (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791499/?tool=pmcentrez Endocannabinoid signaling in microglial cells. The endocannabinoid system and pain. (full - 2009)
(full - 2009)
312
Cannabinoids, Miracle Drug of the 21st Century by Jeffrey Dach MD (web site article/ad - 2009) (has a free e-book)
http://jeffreydach.com/2009/03/09/cannabinoids-miracle-drug-of-the-21st-century-by-jeffrey-dach-md.aspx
The Endocannabinoid System in the Brain: From Biology to Therapy (editorial - 2009)
http://www.benthamdirect.org/pages/b_viewarticle.php?articleID=3136808
2.0 Clinical Pharmacology
(abst - 2009)
An introduction to the endocannabinoid system: from the early to the latest concepts (abst - 2009)
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WBD-4VTDPJT2&_user=10&_origUdi=B6TBG-4Y95RFK3&_fmt=high&_coverDate=02%2F28%2F2009&_rdoc=1&_orig=article&_acct=C000050221&_version= 1&_urlVersion=0&_userid=10&md5=8eec6f23b0ded1d277a88710fc8c37bb
Distribution and function of cannabinoid receptors 1 and 2 in the rat, monkey and human bladder. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19237169 An examination of anthocyanins' and anthocyanidins' affinity for cannabinoid receptors. (abst 2009) http://www.ncbi.nlm.nih.gov/pubmed/20041802 Post-ischemic brain damage: the endocannabinoid system in the mechanisms of neuronal death. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19087195 The endocannabinoid system: Its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitation (abst - 2009)
The endocannabinoid system as a target for the treatment of motor dysfunction. (abst - 2009)
Cannabinoid receptors: a brief history and "what's hot".

(abst - 2009)
313
Endocannabinoid System: An overview of its potential in current medical practice. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19675519/abstract/Endocannabinoid_System:_An_ overview_of_its_potential_in_current_medical_practice__REVIEW_
Cannabinoid receptors in brain: pharmacogenetics, neuropharmacology, neurotoxicology, and potential therapeutic applications (abst 2009) http://pharmgkb.org/pmid/19897083 Enhanced Sweet Taste: Endocannabinoids Act Directly on Tongue Taste Receptors (news - 2009) http://www.sciencedaily.com/releases/2009/12/091222104920.htm The cannabinoid system: cannabinoids and receptors (news 2009)
Motion Sickness, Stress and the Endocannabinoid System

(full - 2010)
The endocannabinoid system as a target for the treatment of neurodegenerative disease (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931550/?tool=pubmed Endocannabinoids selectively enhance sweet taste (full - 2010) (full - 2010)

Evidence for a Role of Endocannabinoids, Astrocytes and p38 Phosphorylation in the Resolution of Postoperative Pain (full - 2010)
The multiple functions of the endocannabinoid system: a focus on the regulation of food intake. (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832623/?tool=pubmed Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression. (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005548/?tool=pubmed Endocannabinoid signalling: has it got rhythm? (full 2010)
Dietary docosahexaenoic acid supplementation alters select physiological endocannabinoid-system metabolites in brain and plasma (full 2010)
http://www.jlr.org/content/51/6/1416.full#content-block
Functional role of cannabinoid receptors in urinary bladder

http://www.indianjurol.com/article.asp?issn=09701591;year=2010;volume=26;issue=1;spage=26;epage=35;aulast=Tyagi
(full - 2010)
314
International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB1 and CB2 (full - 2010)
http://pharmrev.aspetjournals.org/content/62/4/588.long
Involvement of cannabinoid-1 and cannabinoid-2 receptors in septic ileus. (full 2010)

Mice lacking cannabinoid CB1-, CB2-receptors or both receptors show increased susceptibility to trinitrobenzene sulfonic acid (TNBS)-induced colitis. (full 2010)
Rehashing endocannabinoid antagonists: can we selectively target the periphery to safely treat obesity and type 2 diabetes? (full 2010)
Potential role of the cannabinoid receptor CB in the pathogenesis of erosive and nonerosive gastro-oesophageal reflux disease. (abst - 2010)
Deficiency in Endocannabinoid Signaling in the Nucleus Accumbens Induced by Chronic Unpredictable Stress (abst - 2010)
Opposite changes in cannabinoid CB1 and CB2 receptor expression in human gliomas. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20307616 Can autism be triggered by acetaminophen activation of the endocannabinoid system? (abst + link to PDF 2010) http://www.ncbi.nlm.nih.gov/pubmed/20628445 Targeting the Endocannabinoid System for the Treatment of Cancer - A Practical View. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20370711?dopt=Abstract Alterations of the endocannabinoid system in an animal model of migraine: Evaluation in cerebral areas of rat (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19515121 Recent advances in the understanding of the role of the endocannabinoid system in liver diseases. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20934397 The endocannabinoid system in the inflammatory and neurodegenerative processes of multiple sclerosis and of amyotrophic lateral sclerosis. (abst - 2010)
315
The Multiplicity of Action of Cannabinoids: Implications for Treating Neurodegeneration. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20875047 The endocannabinoid signaling system: a marriage of PUFA and musculoskeletal health. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20934863 Non-CB1, non-CB2 receptors for endocannabinoids, plant cannabinoids, and synthetic cannabimimetics: focus on G-protein-coupled receptors and transient receptor potential channels. (abst 2010)
Not Feeling Well? Perhaps You're 'Marijuana Deficient'
(news 2010)
http://www.alternet.org/health/146151/not_feeling_well_perhaps_you%27re_%27marijuana_deficient%27/
Levels And Efficacy Of A Marijuana-Like Substance In The Brain Controlled By Newly Discovered Mechanism (news 2010)
(full 2011) (full 2011) (full 2011)
Cannabinoid system and cyclooxygenases inhibitors

Endocannabinoid system protects against cryptogenic seizures.

(full 2011)
The endocannabinoid system in sepsis a potential target to improve microcirculation? (full 2011)
http://www.signavitae.com/articles/review-articles/161-the-endocannabinoid-system-in-sepsis-a-potentialtarget-to-improve-microcirculation

Role for cannabinoid receptors in human proximal tubular hypertrophy. (full 2011)
316
Update on the endocannabinoid system as an anticancer target. (abst 2011)

Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions. (abst 2011) http://www.nature.com/neuro/journal/v14/n3/full/nn.2736.html A study on the endogenous cannabinoid system synthetic and catabolic enzyme levels in patients with obstructive sleep apnea. (abst 2011)
Molecular reorganization of endocannabinoid signalling in Alzheimer's disease. (abst 2011)

http://www.unboundmedicine.com/medline/ebm/record/21459826/abstract/Molecular_reorganization_of_e ndocannabinoid_signalling_in_Alzheimer%27s_disease_
Homeostatic changes of the endocannabinoid system in Parkinson's disease. (abst 2011)

http://www.unboundmedicine.com/medline/ebm/record/21412829/abstract/Homeostatic_changes_of_the_e ndocannabinoid_system_in_Parkinson%27s_disease_

(abst 2011)
The endocannabinoid system in prostate cancer.

(abst 2011)
The highs and lows of cannabinoid receptor expression in disease: mechanisms and their therapeutic implications. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21752875 Early exposure to Environmental enrichment alters the expression of genes of the endocannabinoid system (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21419109/abstract/Early_exposure_to_Environme ntal_enrichment_alters_the_expression_of_genes_of_the_endocannabinoid_system_
Endocannabinoid signaling in the amygdala: anatomy, synaptic signaling, behavior, and adaptations to stress. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21884761 -Tocopherol and -tocopheryl phosphate interact with the cannabinoid system in the rodent hippocampus. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21843633 Alternative targets within the endocannabinoid system for future treatment of gastrointestinal diseases. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21876860
317
Cannabis sativa and the endogenous cannabinoid system: therapeutic potential for appetite regulation. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21213357 Endocannabinoid system dysfunction in mood and related disorders.
(abst 2011)
Interictal Type 1 Cannabinoid Receptor Binding is Increased in Female Migraine Patients. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22077199 In vivo activation of endocannabinoid system in temporal lobe epilepsy with hippocampal sclerosis. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21303859 The Endocannabinoid System: Plant-Derived Cannabinoids in Diabetes and Diabetic Complications. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22155112 Effects of endocannabinoid system modulation on cognitive and emotional behavior. (abst 2011) http://marijuana.researchtoday.net/archive/8/9/4801.htm ENDOGENOUS CANNABINOID SYSTEM REGULATES INTESTINAL BARRIER FUNCTION IN VIVO THROUGH CANNABINOID TYPE 1 RECEPTOR ACTIVATION (abst 2011)
The genetic basis of the endocannabinoid system and drug addiction in humans (abst 2011) http://jop.sagepub.com/content/early/2011/09/20/0269881111416689 Omega-3 PUFA Deficiency Abolishes Endocannabinoid-Linked Neuronal Functions (news - 2011) http://www.fatsoflife.com/article.php?nid=1&edition=this&id=1837&issueid=85 Omega-3 deficiency disrupts cannibinoid receptor function in brain (news 2011)
A Brain Wrought Without Omega-3
(news 2011) (news 2011) (news 2011)
Introduction to the Endocannabinoid System

Marijuana Compound Treats Multiple Health Issues

http://www.foxnews.com/health/2010/03/10/cannabis-deficient
318
Pot and Pumpkin Pie: Endocannabinoid System Enhanced by Vitamin E (news 2011)
http://www.examiner.com/medical-marijuana-in-philadelphia/pot-and-pumpkin-pie-endocannabinoidsystem-enhanced-by-vitamin-e
Poor Diet Impairs Cannabinoid Receptors Chocolate & marijuana: chemical cousins
(news 2011) (news 2011)
http://www.freedomisgreen.com/poor-diet-impairs-cannabinoid-receptors/
Extinction learning of rewards in the rat: is there a role for CB1 receptors? (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/21519986
ENDOMETRIOSIS Endometriosis Cesamet (Nabilone) (anecdotal- 2007)

http://curetogether.com/Endometriosis/1194/treatments/Cesamet%20%28Nabilone%29
Selective CB2 up-regulation in women affected by endometrial inflammation (abst 2008)

http://onlinelibrary.wiley.com/doi/10.1111/j.15824934.2007.00085.x/abstract;jsessionid=BD44AAB1B6C3DE22D4D53D17EFEACC73.d02t02
Effect of palmitoylethanolamide-polydatin combination on chronic pelvic pain associated with endometriosis: preliminary observations. (abst 2010)
Antiproliferative effects of cannabinoid agonists on deep infiltrating endometriosis. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/21057002 Endocannabinoid involvement in endometriosis.
(abst 2010)
EPILEPSY/ SEIZURES Marijuana and Epilepsy (anecdotal- no date)

http://www.rxmarihuana.com/epilepsy.htm
Anti-epileptic Action of Marijuana-Active Substances

(full - 1949)
Anticonvulsant nature of marihuana smoking.
(abst - 1975)
319
Anticonvulsant activity of four oxygenated cannabidiol derivatives. (abst 1975)

Cannabidiol--antiepileptic drug comparisons and interactions in experimentally induced seizures in rats. (full - 1977)
Anticonvulsant Action of Cannabis in the Rat: Role of Brain Monoamines. (abst 1978) http://www.ncbi.nlm.nih.gov/pubmed/104333 Chronic administration of cannabidiol to healthy volunteers and epileptic patients. (abst - 1980) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=42 Antiepileptic potential of cannabidiol analogs.
(abst - 1981) (abst - 1981) (abst - 1981)
The cannabinoids as potential antiepileptics.

Hypnotic and Antiepileptic Effects of Cannabidiol

Anticonvulsant effects of the (-) and (+)isomers of cannabidiol and their dimethylheptyl homologs. (abst - 1982)
Effects of cannabidiol on behavioral seizures caused by convulsant drugs or current in mice. (abst - 1982) http://www.ncbi.nlm.nih.gov/pubmed/6129147 ILLICIT DRUG USE AND THE RISK OF NEW-ONSET SEIZURES (abst 1990)
http://aje.oxfordjournals.org/content/132/1/47.abstract?sid=9fd403c4-2e6e-4df4-a57c-208434b8ad0a
Marijuana use and the risk of new onset seizures.
(full - 1992)
Treatment with CBD in oily solution of drug-resistant paediatric epilepsies. (full - 2001) http://www.cannabismed.org/studies/ww_en_db_study_show.php?s_id=173&&search_pattern=EPILEPSY

(full - 2001)
Anticonvulsant activity of N-palmitoylethanolamide, a putative endocannabinoid, in mice. (abst 2001) http://www.ncbi.nlm.nih.gov/pubmed/11442148
320
Alcohol and marijuana: effects on epilepsy and use by patients with epilepsy. (abst 2001) http://www.ncbi.nlm.nih.gov/pubmed/11737161 The Endogenous Cannabinoid System Regulates Seizure Frequency and Duration in a Model of Temporal Lobe Epilepsy (full - 2003)

(abst - 2003) (abst - 2003)
On the application of cannabis in paediatrics and epileptology.

Cannabis may help epileptics
(news - 2003)
Cannabis 'could help epileptics' (news - 2003) http://news.bbc.co.uk/2/hi/health/3162000.stm Marijuana Use More Prevalent With Epilepsy (needs free registration) (news - 2003) http://www.medscape.com/viewarticle/465891 Endocannabinoids and Their Implications for Epilepsy Cannabinoids: Defending the Epileptic Brain (full - 2004)
(full - 2004)
Marijuana use and epilepsy - Prevalence in patients of a tertiary care epilepsy center (abst - 2004)
http://www.neurology.org/cgi/content/abstract/62/11/2095?maxtoshow=&hits=80&RESULTFORMAT=&f ulltext=marihuana&searchid=1&FIRSTINDEX=1760&resourcetype=HWCIT
Epilepsy patients are smoking pot
(news - 2004) (abst 2005)
Cannabinoids as potential anti-epileptic drugs.
Anandamide Induced Anti-Convulsion in an In Vitro Model of Epilepsy

http://www.kau.edu.sa/centers/spc/jkau/Doc/Med/12/Mada.pdf
(abst - 2005)
Selective antiepileptic effects of N-palmitoylethanolamide, a putative endocannabinoid. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/15461672 Not Too Excited? Thank Your Endocannabinoids (full - 2006)
321
Forebrain-Specific Inactivation of Gq/G11 Family G Proteins Results in Age-Dependent Epilepsy and Impaired Endocannabinoid Formation (full - 2006)
http://mcb.asm.org/cgi/content/full/26/15/5888?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=can nabinoid&searchid=1&FIRSTINDEX=1360&resourcetype=HWCIT
The Endocannabinoid System Controls Key Epileptogenic Circuits in the Hippocampus (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769341/?tool=pmcentrez Cannabinoid CB1 receptor antagonists cause status epilepticus-like activity in the hippocampal neuronal culture model of acquired epilepsy (full - 2006)
Activation of the Cannabinoid Type-1 Receptor Mediates the Anticonvulsant Properties of Cannabinoids in the Hippocampal Neuronal Culture Models of Acquired Epilepsy and Status Epilepticus (full - 2006)
Arachidonyl-2'-chloroethylamide, a highly selective cannabinoid CB1 receptor agonist, enhances the anticonvulsant action of valproate in the mouse maximal electroshockinduced seizure model. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16930590 Brain's Cannabinoid System 'Mellows' Seizures Brain's cannabinoid system fights seizures
(news - 2006)
(news 2006)
Downregulation of the CB1 Cannabinoid Receptor and Related Molecular Elements of the Endocannabinoid System in Epileptic Human Hippocampus (full - 2007)
Endocannabinoids block status epilepticus in cultured hippocampal neurons (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2617750/?tool=pmcentrez Development of pharmacoresistance to benzodiazepines but not cannabinoids in the hippocampal neuronal culture model of status epilepticus (full - 2007)
Marijuana: an effective antiepileptic treatment in partial epilepsy?

(abst - 2007)
322
The phytocannabinoid Delta(9)-tetrahydrocannabivarin modulates inhibitory neurotransmission in the cerebellum. (full 2008)
The cannabinoid anticonvulsant effect on pentylenetetrazole-induced seizure is potentiated by ultra-low dose naltrexone in mice (abst 2008)
Prolonged exposure to WIN55,212-2 causes downregulation of the CB1 receptor and the development of tolerance to its anticonvulsant effects in the hippocampal neuronal culture model of acquired epilepsy. (full 2009)
Effect of arachidonyl-2'-chloroethylamide, a selective cannabinoid CB1 receptor agonist, on the protective action of the various antiepileptic drugs in the mouse maximal electroshock-induced seizure model. (abst 2009)
Involvement of nitrergic system in the anticonvulsant effect of the cannabinoid CB(1) agonist ACEA in the pentylenetetrazole-induced seizure in mice. (abst 2009)
Cannabidiol Displays Antiepileptiform and Antiseizure Properties In Vitro and In Vivo (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819831/?tool=pmcentrez Cannabinoid-mediated inhibition of recurrent excitatory circuitry in the dentate gyrus in a mouse model of temporal lobe epilepsy. (full 2010)
Delta-Tetrahydrocannabivarin suppresses in vitro epileptiform and in vivo seizure activity in adult rats. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20196794 Anticonvulsant effects of GWP42006 in vitro and in vivo in rat (abst - 2010)
Dynamic changes of CB1-receptor expression in hippocampi of epileptic mice and humans. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20618415
323

(full 2011) (full 2011)
Convulsions Associated with the Use of a Synthetic Cannabinoid Product.

http://www.springerlink.com/content/9651q2672027n38g/fulltext.html
Pro-epileptic effects of the cannabinoid receptor antagonist SR141716 in a model of audiogenic epilepsy. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21733658 Synthetic cannabinoid WIN 55,212-2 mesylate enhances the protective action of four classical antiepileptic drugs against maximal electroshock-induced seizures in mice. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21238473/abstract/Synthetic_cannabinoid_WIN_5 5212_2_mesylate_enhances_the_protective_action_of_four_classical_antiepileptic_drugs_against_maxima l_electroshock_induced_seizures_in_mice_
Protective effects of CB1 receptor agonist WIN 55.212-2 in seizure activity in the model of temporal lobe epilepsy (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21469332/abstract/%5BProtective_effects_of_CB1 _receptor_agonist_WIN_55_212_2_in_seizure_activity_in_the_model_of_temporal_lobe_epilepsy%5D_
Changes in the cannabinoid (CB1) receptor expression level and G-protein activation in kainic acid induced seizures. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22079489 In vivo activation of endocannabinoid system in temporal lobe epilepsy with hippocampal sclerosis. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21303859 Marijuana, endocannabinoids, and epilepsy: Potential and challenges for improved therapeutic intervention. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/22178327 Cannabis could help treat epilepsy (news 2011) (news 2011) (news - 2011)
Cannabis could be used to treat epilepsy
New research provides hope for those with epilepsy

Inverse relationship of cannabimimetic (R+)WIN 55, 212 on behavior and seizure threshold during the juvenile period. (abst 2012)
'Hammer Head' 'incense' blamed for seizure of youth in Le Roy
(news 2012)
http://thebatavian.com/howard-owens/hammer-head-incense-blamed-seizure-youth-le-roy/29983
324
FAMILIAL MEDITERRANEAN FEVER Pain relief with oral cannabinoids in familial Mediterranean fever.
(abst - 1997)
FERTILITY/ SEXUAL FUNCTION Hemp Packs in Powerful Source of Preconception Nutrition (article - no date)
An attitude survey of the effects of marijuana on sexual enjoyment.

(abst 1979)
Endocrine effects of marijuana in the male: preclinical studies

(abst - 1984)
Acute effects of smoking marijuana on hormones, subjective effects and performance in male human subjects (abst - 1986)
http://www.ncbi.nlm.nih.gov/pubmed?term=Acute%20effects%20of%20smoking%20marijuana%20on%2 0hormones%2C%20subjective%20effects%20and%20performance%20in%20male%20human%20subjects
Tolerance to the luteinizing hormone and prolactin suppressive effects of delta-9tetrahydrocannabinol develops during chronic prepubertal treatment of female rats. (abst - 1986)
http://jpet.aspetjournals.org/content/238/3/1034.abstract?maxtoshow=&hits=80&RESULTFORMAT=&ful ltext=cannabis&searchid=1&FIRSTINDEX=3760&resourcetype=HWCIT
Molecular cloning of a human cannabinoid receptor which is also expressed in testis (abst 1991) http://pharmgkb.org/pmid/1718258 Inhibitory effects of the cannabinoid agonist HU 210 on rat sexual behaviour. (abst 2000) http://www.ncbi.nlm.nih.gov/pubmed/10913795 Dysregulated Cannabinoid Signaling Disrupts Uterine Receptivity for Embryo Implantation (full - 2001) http://www.jbc.org/content/276/23/20523.full Cannabis-induced Koro in Americans. (abst 2001)
http://medical-journals.healia.com/doc/11784462/Cannabis-induced-Koro-in-Americans
325
Contrasting effects of WIN 55212-2 on motility of the rat bladder and uterus. (full 2002) http://www.jneurosci.org/content/22/16/7147.long Endocannabinoids, hormone-cytokine networks and human fertility
(abst - 2002)
Stage-variations of anandamide hydrolase activity in the mouse uterus during the natural oestrus cycle (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440866/?tool=pubmed Jekyll and Hyde: Two Faces of Cannabinoid Signaling in Male and Female Fertility (full - 2006)
http://edrv.endojournals.org/cgi/content/full/27/5/427?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabis&searchid=1&FIRSTINDEX=1120&resourcetype=HWCIT
Marijuana Improves Fertility in Tobacco Smokers Synthetic Cannabinoid May Aid Fertility In Smokers
(news 2006) (news - 2006) (news - 2006)
http://news.softpedia.com/news/Marijuana-Improves-Fertility-in-Tobacco-Smokers-41535.shtml
Cannabis-based boost for smokers' suffering sperm
http://www.newscientist.com/article/dn10362-cannabisbased-boost-for-smokers-suffering-sperm.html
Marijuana-like Chemical Can Restore Sperm Function Lost to Tobacco Abuse (news - 2006) http://www.rxpgnews.com/specialtopics/article_5093.shtml The role of the endocannabinoid system in gametogenesis, implantation and early pregnancy (full - 2007)
http://humupd.oxfordjournals.org/cgi/content/full/13/5/501?maxtoshow=&hits=80&RESULTFORMAT=& fulltext=cannabinoid&searchid=1&FIRSTINDEX=960&resourcetype=HWCIT

(full - 2008)
CB2 receptors in reproduction Fertility (article - 2008)
(full - 2008)
http://www.cannabismd.net/fertility/
326
Interplay between endocannabinoids, steroids and cytokines in the control of human reproduction. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18426505 Localisation and Function of the Endocannabinoid System in the Human Ovary (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640464/?tool=pmcentrez The endocannabinoid system in bull sperm and bovine oviductal epithelium: role of anandamide in sperm-oviduct interaction. (full - 2009)
http://www.reproduction-online.org/cgi/content/full/137/3/403
The endocannabinoid 2-arachidonoylglycerol promotes sperm developement through activation of cannabinoid-2 receptors (abst 2009)
Cannabinoid/Endocannabinoid signaling impact on early pregnancy events. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/21104387 Cannabinoids and Reproduction: A Lasting and Intriguing History
(full 2010)
Localization and function of cannabinoid receptors in the corpus cavernosum: basis for modulation of nitric oxide synthase nerve activity. (abst 2010)
Modulation of the novel cannabinoid receptor - GPR55 - during rat fetoplacental development. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21497900 Effects of the cannabinoid antagonist SR 141716 on sexual and motor behavior in receptive female rats. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21848907 My Green Valentine: Sex and marijuana (news/interview 2011)
http://www.examiner.com/norml-in-philadelphia/my-green-valentine-sex-and-marijuana
FEVER/ TEMPERATURE CONTROL The effects of (-)-9-tetrahydrocannabinol on reserpine-induced hypothermia in rats (full - 1973) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1776374/?page=1 EVALUATION OF THE HYPOTHERMIC ACTION OF TETRAHYDROCANNABINOLS IN AND SQUIRREL MONKEYS
(abst - 1973)
http://jpet.aspetjournals.org/content/187/3/568.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=cannabis&searchid=1&FIRSTINDEX=2560&resourcetype=HWCIT
327
Absence of interaction between delta9-tetrahydrocannabinol (delta-THC) and cannabidiol (CBD) in aggression, muscle control and body temperature experiments in mice. (abst 1975) http://www.ncbi.nlm.nih.gov/pubmed/1171491 Marijuana Smoking and Cold Tolerance in Man. (abst 1976)
http://medical-journals.healia.com/doc/779756/Marijuana-smoking-and-cold-tolerance-in-man
Effects of delta9-tetrahydrocannabinol on the rates of oxygen consumption of mice. (full 1977) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1667385/pdf/brjpharm00447-0081.pdf Profound hypothermia in mammals treated with tetrahydrocannabinols, morphine, or chlorpromazine. (abst 1977) http://www.ncbi.nlm.nih.gov/pubmed/913617 The effects of cannabinoids on body temperature and brain catecholamine synthesis. (abst - 1978)
Effects of delta 9-tetrahydrocannabinol, 2.4-dinitrophenol and pentolinium tartrate on behavioural thermoregulation in mice. (full 1979)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2043799/pdf/brjpharm00668-0046.pdf
Changes in body temperature and oxygen consumption rate of conscious mice produced by intrahypothalamic and intracerebroventricular injections of delta 9tetrahydrocannabinol. (full 1982)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2071615/pdf/brjpharm00634-0142.pdf
Antiinflammatory and antimicrobial compounds and compositions United States Patent 4837228 (full - 1989) http://www.freepatentsonline.com/4837228.html CB1 Receptors in the Preoptic Anterior Hypothalamus Regulate WIN 55212-2 [(4,5Dihydro-2-methyl-4(4-morpholinylmethyl)-1-(1-naphthalenyl-carbonyl)-6Hpyrrolo[3,2,1ij]quinolin-6-one]-Induced Hypothermia (full - 2002)
Drug-Induced Hypothermia Reduces Ischemic Damage
(full - 2003)
http://stroke.ahajournals.org/cgi/content/full/34/8/2000?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=cannabinoid&searchid=1&FIRSTINDEX=80&resourcetype=HWCIT
Cannabinoids prevent the acute hyperthermia and partially protect against the 5-HT depleting effects of MDMA ("Ecstasy") in rats. (abst - 2004)
A Cooling Effect From Cannabis?
(news - 2005) (news - 2005)
http://ccrmg.org/journal/05aut/coolcannabis.html
Marijuana Might Really Make You Cool
http://www.thehempire.com/index.php/cannabis/news/marijuana_might_really_make_you_cool
328
A Novel Role of Cannabinoids: Implication in the Fever Induced by Bacterial Lipopolysaccharide (full - 2007) http://jpet.aspetjournals.org/cgi/content/full/320/3/1127 Effects of a Selective Cannabinoid Agonist and Antagonist on Body Temperature in Rats (abst - 2007)
Repeated Treatment with Cannabidiol but Not Delta9-tetrahydrocannabinol Has a Neuroprotective Effect Without the Development of Tolerance (abst - 2007)
Behavioral and temperature effects of delta 9-tetrahydrocannabinol in human-relevant doses in rats (full - 2008)
Endogenous cannabinoids induce fever through the activation of CB1 receptors. (full 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765314/?tool=pubmed Pharmacologically induced hypothermia with cannabinoid receptor agonist WIN55, 2122 after cardiopulmonary resuscitation (abst 2010)
http://journals.lww.com/ccmjournal/Abstract/2010/12000/Pharmacologically_induced_hypothermia_with.2 .aspx
FIBROMYALGIA Cannabis Sativa (Marijuana) for Fibromyalgia

http://www.fibromyalgia-reviews.com/Drg_Marijuana.cfm
(list -no date)
Cannabis for Chronic Pain: Case Series and Implications for Clinicians (abst - 2002) http://www.prohealth.com//library/showArticle.cfm?libid=8711 Clinical Endocannabinoid Deficiency
(full - 2004)
Fibromyalgia, IBS, and the Endocannabinoid-CB-Receptor (ECBR) system (abst - 2004)

Chronic Pain and Cannabinoids
(full 2005)
http://www.drkoprp.com/pdfs/fibromyalgia/CannabinoidsPPM.pdf
329
Delta-9-THC based monotherapy in fibromyalgia patients on experimentally induced pain, axon reflex flare, and pain relief (abst - 2006)
THC Reduces Pain in Fibromyalgia Patients

(news - 2006) (abst - 2007) (news - 2007)
Study of analgesic effects of oral THC in Germany ...

Fibromyalgia: Effective Treatment with Medical Marijuana Synthetic Cannabis for Fibromyalgia Pain? (news - 2007)
http://www.salem-news.com/articles/november292007/leveque_fybromyalgia_112807.php
http://www.healthcentral.com/chronic-pain/c/5949/16104/fm-pain
Are cannabinoids a new treatment option for pain in patients with fibromyalgia? (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18521112 Anandamide and neutrophil function in patients with fibromyalgia.
(abst - 2008)
Nabilone for the treatment of pain in fibromyalgia.

(abst - 2008)
Expression of the endocannabinoid system in fibroblasts and myofascial tissues. (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/19083670 Marijuana-Based Drug Reduces Fibromyalgia Pain, Study Suggests
(news - 2008)
Fibromyalgia and Medical Marijuana
(news - 2008) (news - 2008) (news - 2008)
http://www.webmd.com/fibromyalgia/guide/fibromyalgia-and-medical-marijuana
Marijuana Ingredient May Cut Fibromyalgia Pain
http://www.webmd.com/fibromyalgia/news/20080219/pot-drug-may-cut-fibromyalgia-pain
Marijuana Derivative Called Effective in Fibromyalgia

http://www.medpagetoday.com/Rheumatology/Fibromyalgia/8377
Tetrahydrocannabinol (Delta 9-THC) Treatment in Chronic Central Neuropathic Pain and Fibromyalgia Patients: Results of a Multicenter Survey (full - 2009)
http://www.hindawi.com/journals/arp/2009/827290.html
Cannabinoids, endocannabinoids, and related analogs in inflammation. (full 2009)

The Effects of Nabilone on Sleep in Fibromyalgia: Results of a Randomized Controlled Trial. (full - 2010) http://www.anesthesia-analgesia.org/content/110/2/604.long
330
Medical marijuana may help fibromyalgia pain
(news - 2010)
http://www.cnn.com/2010/HEALTH/02/22/medical.marijuana/
Cannabis Use in Patients with Fibromyalgia: Effect on Symptoms Relief and HealthRelated Quality of Life (full 2011)
Cannabinoids for Treatment of Chronic Non-Cancer Pain; a Systematic Review of Randomized Trials. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21426373 Inhaled Cannabis Beneficial For Fibromyalgia Patients, Study Says
(news 2011)
FLU / INFLUENZA Modulation of airway responses to influenza A/PR/8/34 by Delta9-tetrahydrocannabinol in C57BL/6 mice. (full 2007) http://jpet.aspetjournals.org/content/323/2/675.long Targeted deletion of cannabinoid receptors CB1 and CB2 produced enhanced inflammatory responses to influenza A/PR/8/34 in the absence and presence of Delta9tetrahydrocannabinol. (full 2008) http://www.jleukbio.org/content/83/3/785.long Can cannabis cure swine flu? (news 2009) (news 2009)
http://blogs.westword.com/latestword/2009/08/can_cannabis_cure_swine_flu.php#more
Cannabis shows promise as treatment for swine flu
http://www.examiner.com/libertarian-in-new-york/cannabis-shows-promise-as-treatment-for-swine-flu
Phytocannabinoid scientists unveils lozenge to treat H1N1 swine flu and H5N1 bird flu (news/ad -2009)
http://www.examiner.com/examiner/x-7002-Pittsburgh-History-Examiner~y2009m6d11Phytocannabinoid-scientists-unveils-lozenge-to-treat--H1N1-swine-flu-and-H5N1-bird-flu#comments
GATEWAY THEORY The Myth of Marijuana's Gateway Effect

http://www.druglibrary.org/schaffer/library/mjgate.htm
(news - no date)
331
Marijuana And The Gateway Theory

http://www.ukcia.org/research/gateway.php
(full - 1996) (full - 1997)
Cannabis Use- A Gateway to other Drugs? The Case of Amsterdam

http://www.cedro-uva.org/lib/cohen.cannabis.pdf
Does cannabis lead to taking other drugs?

http://www.ukcia.org/research/gateway2.php
(faq - 1998)
Delta9-tetrahydrocannabinol releases and facilitates the effects of endogenous enkephalins: reduction in morphine withdrawal syndrome without change in rewarding effect. (abst 2001) http://www.ncbi.nlm.nih.gov/pubmed/11359533 Reassessing the gateway effect (full - 2002) (letter - 2003)
http://www.ukcia.org/research/ReassessingGatewayEffect.pdf
Twin study fails to prove 'gateway' hypothesis Is cannabis a stepping-stone for cocaine?
http://www.ukcia.org/research/EscalationOfDrugUse/TwinStudyFailsToProveGateway.html
(abst 2003) (abst - 2004)
Endogenous cannabinoids are not involved in cocaine reinforcement
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T26-4CMHYKD1&_user=10&_coverDate=01%2F31%2F2005&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct= C000050221&_version=1&_urlVersion=0&_userid=10&md5=01b53cd805067db7ca4e861a90579fac
Study Questions Marijuana As Gateway Drug
(news - 2006)
http://www.drugfree.org/join-together/drugs/study-says-marijuana-is-no
No 'Smoking' Gun: Research Indicates Teen Marijuana Use Does Not Predict Drug, Alcohol Abuse (news - 2006) http://www.sciencedaily.com/releases/2006/12/061204123422.htm Gateway To Nowhere? The Evidence That Pot Doesn't Lead To Heroin (news - 2006)
http://www.thehempire.com/index.php/cannabis/news/gateway_to_nowhere_the_evidence_that_pot_doesnt _lead_to_heroin
Study of 4000 indicates marijuana discourages use of hard drugs.

http://www.csdp.org/publicservice/medicalmj08.htm
(news 2008)
Adolescent Exposure to Chronic Delta-9-Tetrahydrocannabinol Blocks Opiate Dependence in Maternally Deprived Rats (full - 2009)
332
CLAIM #13:MARIJUANA IS A "GATEWAY" TO THE USE OF OTHER DRUGS (news - 2009) http://www.erowid.org/plants/cannabis/cannabis_myth13.shtml The Surprising Effect Of Marijuana On Morphine Dependence
(news - 2009)
Active Ingredient In Cannabis Eliminates Morphine Dependence In Rats (news - 2009) http://www.sciencedaily.com/releases/2009/07/090706090440.htm Evaluating the drug use "gateway" theory using cross-national data: Consistency and associations of the order of initiation of drug use among participants in the WHO World Mental Health Surveys. (full - 2010)
Risk Of Marijuana's 'Gateway Effect' Overblown
(news - 2010)
http://www.redorbit.com/news/science/1912017/risk_of_marijuanas_gateway_effect_overblown/index.htm l?source=r_science
Teen Pot Smoking Won't Lead to Other Drugs as Adults
(news- 2010)
Previous exposure to delta9-tetrahydrocannibinol enhances locomotor responding to but not self-administration of amphetamine. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21389094/abstract/Previous_exposure_to_delta9_t etrahydrocannibinol_enhances_locomotor_responding_to_but_not_self_administration_of_amphetamine_
GENDER-BASED DIFFERENCES Women Find Healthy Hormone Balance with Hemp ( ad/ article - no date)
http://manitobaharvest.com/articles_studies/3815/Women-Find-Healthy-Hormone-Balance-withHemp.html
Marijuana withdrawal syndrome in a woman.

(abst 1984) (abst 1986) (abst 1988)
Concordant alcohol and marihuana use in women.


Effects of chronic marijuana use on testosterone, luteinizing hormone, follicle stimulating hormone, prolactin and cortisol in men and women. (abst - 1991)
333
Sex steroid influence on cannabinoid CB(1) receptor mRNA and endocannabinoid levels in the anterior pituitary gland. (abst 2000) http://www.ncbi.nlm.nih.gov/pubmed/10733937 How might cannabinoids influence sexual behavior? (full - 2001)
http://www.pnas.org/content/98/3/793.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabi noid&searchid=1&FIRSTINDEX=880&resourcetype=HWCIT
Sex Differences in Antinociceptive and Motoric Effects of Cannabinoids.
(abst - 2001)
http://medical-journals.healia.com/doc/11698061/Sex-differences-in-antinociceptive-and-motoric-effectsof-cannabinoids
Cb(1) Receptor Mediation of Cannabinoid Behavioral Effects in Male and Female Rats. (abst - 2004)
http://medical-journals.healia.com/doc/14991224/CB1-receptor-mediation-of-cannabinoid-behavioraleffects-in-male-and-female-rats
Sex differences in the cannabinoid modulation of an A-type K+ current in neurons of the mammalian hypothalamus. (full 2005) http://jn.physiology.org/content/94/4/2983.long Biochemical Changes in Endocannabinoid System are Expressed in Platelets of Female but not Male Migraineurs (abst - 2006)
http://cep.sagepub.com/cgi/content/abstract/26/3/277?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabinoid&searchid=1&FIRSTINDEX=1200&resourcetype=HWCIT
Cannabis reward: biased towards the fairer sex?

(full - 2007)
Cannabinoid self-administration in rats: sex differences and the influence of ovarian function (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190022/ Endocannabinoids Mediate the Effects of Acute Stress and Corticosterone on Sex Behavior (full 2007) http://endo.endojournals.org/content/148/2/493.full Driving under the influence of cannabis: a 10-year study of age and gender differences in the concentrations of tetrahydrocannabinol in blood. (abst - 2008)
Male-female differences in the effects of cannabinoids on sexual behavior and gonadal hormone function. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19733173 Protracted cannabinoid administration elicits antidepressant behavioral responses in rats: role of gender and noradrenergic transmission. (abst - 2009)
Female sex, but not male sex, better with cannabis
(news 2009)
http://www.examiner.com/health-science-in-vancouver/female-sex-but-not-male-sex-better-with-cannabis
Sex Differences in the Effects of Marijuana on Simulated Driving Performance (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033009/?tool=pmcentrez
334
Drug- and cue-induced reinstatement of cannabinoid-seeking behaviour in male and female rats: influence of ovarian hormones. (abst - 2010)
How important are sex differences in cannabinoid action?

(abst - 2010)
Exposure to a high-fat diet decreases sensitivity to 9-tetrahydrocannabinol-induced motor effects in female rats (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20850461 Sex difference in cell proliferation in developing rat amygdala mediated by endocannabinoids has implications for social behavior (full 2011)
Sex, drugs, and cognition: effects of marijuana.
(full 2011)
Cannabinoid receptor expression and phosphorylation are differentially regulated between male and female cerebellum and brain stem after repeated stress: Implication for PTSD and drug abuse. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21600961 Gender differences in adolescent marijuana use and associated psychosocial characteristics. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21769049 Effects of the cannabinoid antagonist SR 141716 on sexual and motor behavior in receptive female rats. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21848907 Gender-dependent increases with healthy aging of the human cerebral cannabinoid-type 1 receptor binding using [(18)F]MK-9470 PET. (abst 2011)
Antinociception and sedation following intracerebroventricular administration of tetrahydrocannabinol in female vs. male rats. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/20692296/abstract/Antinociception_and_sedation_ following_intracerebroventricular_administration_of_%CE%94%E2%81%B9_tetrahydrocannabinol_in_fe male_vs__male_rats_
335
Health effects of using cannabis for therapeutic purposes: a gender analysis of users' perspectives. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21138343 Cyclic vomiting syndrome and functional vomiting in adults: association with cannabinoid use in males. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/21951771
GERD/GASTRO-ESOPHAGEAL REFLUX - also see BOWEL DISORDERS Cannabinoid1 receptor in the dorsal vagal complex modulates lower oesophageal sphincter relaxation in ferrets (full 2003) http://jp.physoc.org/content/550/1/149.full Cannabinoids for gastrointestinal diseases: potential therapeutic applications. (abst - 2003) http://www.ncbi.nlm.nih.gov/pubmed/12517253 Involvement of cannabinoid receptors in gut motility and visceral perception (full - 2004) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574910/?tool=pmcentrez Cannabinoid CB(2) receptor activation prevents bronchoconstriction and airway oedema in a model of gastro-oesophageal reflux. (abst - 2007)
Effect of 9-tetrahydrocannabinol, a cannabinoid receptor agonist, on the triggering of transient lower oesophageal sphincter relaxations in dogs and humans (full - 2008)
Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects (full 2008) http://gut.bmj.com/content/57/8/1140.full Potential role of the cannabinoid receptor CB in the pathogenesis of erosive and nonerosive gastro-oesophageal reflux disease. (abst - 2010)
Beyond acid suppression: new pharmacologic approaches for treatment of GERD. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20425477
GLAUCOMA - also see VISION Marihuana smoking and intraocular pressure. (abst - 1971)
336
Marihuana and the eye.
(full - 1975)
http://www.iovs.org/cgi/reprint/14/4/261
Marijuana smoking and reduced pressure in human eyes: drug action or epiphenomenon? (full - 1975)
http://www.iovs.org/cgi/reprint/14/1/52?ijkey=80da88f4d9414647a92b76d12895d1108a725d85
Editorial: Cannabis and eye function.
(full - 1976) http://www.iovs.org/cgi/reprint/15/4/243
Interaction of adrenergic antagonists with prostaglandin E2 and tetrahydrocannabinol in the eye. (full - 1976) http://www.iovs.org/cgi/reprint/15/2/102 Marijuana and vision--after ten years' use in Costa Rica.
http://www.iovs.org/cgi/reprint/16/8/689
(full - 1977) (abst - 1977) (abst - 1979)
Effect of delta-9-tetrahydrocannabinol on intraocular pressure in humans.

Effects of tetrahydrocannabinol on arterial and intraocular hypertension.

US Patent 4189491 - Tetrahydrocannabinol in a method of treating glaucoma (full - 1980) http://www.patentstorm.us/patents/4189491.html Effect of marihuana on intraocular and blood pressure in glaucoma (full - 1980) (abst - 1981)
Topical delta 9-tetrahydrocannabinol and aqueous dynamics in glaucoma

Cannabinoids in glaucoma: a primary screening procedure. (abst 1981)

Isolation of ocular hypotensive agents from Cannabis sativa
(abst - 1981)
http://jcp.sagepub.com/cgi/content/abstract/21/8_suppl/479S?maxtoshow=&hits=80&RESULTFORMAT= &fulltext=marihuana&searchid=1&FIRSTINDEX=240&resourcetype=HWCIT
Glaucoma, hypertension, and marijuana.
(full -1982)
Ocular Effects of Topical Administration of {Delta}9-Tetrahydrocannabinol in Man (full - 1982)

http://archopht.amaassn.org/cgi/reprint/100/2/265?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searc hid=1&FIRSTINDEX=2960&resourcetype=HWCIT
Intraocular pressure following systemic administration of cannabinoids.

(abst - 1982)
337
Multiple-Drop Study of Topically Applied 1% {Delta}9-Tetrahydrocannabinol in Human Eyes (full - 1983)

http://archopht.amaassn.org/cgi/reprint/101/4/591?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid= 1&FIRSTINDEX=2800&resourcetype=HWCIT
Intraocular pressure, ocular toxicity and neurotoxicity after administration of delta 9tetrahydrocannabinol or cannabichromene. (abst 1984)
Ocular Hypotension, Ocular Toxicity, and Neurotoxicity in Response to Marihuana Extract and Cannabidiol. (abst - 1984)
Central Nervous System and Peripheral Mechanisms in Ocular Hypotensive Effect of Cannabinoids (full- 1987)
A comparison of the ocular and central effects of delta 9-tetrahydrocannabinol and cannabigerol. (abst - 1990) http://www.ncbi.nlm.nih.gov/pubmed/1965836 Patent 5631297 - Anandamides useful for the treatment of intraocular hypertension, ophthalmic compositions containing the same and methods of use of the same (full 1997) http://www.patentstorm.us/patents/5631297/fulltext.html Marijuana Smoking vs Cannabinoids for Glaucoma Therapy
http://archopht.ama-assn.org/cgi/content/full/116/11/1433
(full - 1998)
Smoking dope restored my sight

(news/anecdotal - 1998) (abst 1999)

Involvement of Cannabinoid Receptors in the Intraocular Pressure-Lowering Effects of WIN55212-2 (full - 2000) http://jpet.aspetjournals.org/content/292/1/136.long Therapeutic aspects of cannabis and cannabinoids.
(full - 2001)
Chronic Cannabis Use in the Compassionate Investigational New Drug Program: An Examination of Benefits and Adverse Effects of Legal Clinical Cannabis (full 2002) http://proxy.baremetal.com/cannabiscoalition.ca/chronic.pdf
338
Delta-9-tetrahydrocannabinol (THC) in the treatment of end-stage open-angle glaucoma. (full - 2002)

Effect of WIN 55212-2, a Cannabinoid Receptor Agonist, on Aqueous Humor Dynamics in Monkeys (full - 2003)
http://archopht.amaassn.org/cgi/content/full/121/1/87?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuana&sear chid=1&FIRSTINDEX=640&resourcetype=HWCIT
Cannabinoids and glaucoma
(full - 2004)
CB2 cannabinoid receptors in trabecular meshwork cells mediate JWH015-induced enhancement of aqueous humor outflow facility. (full - 2005)
Finding of endocannabinoids in human eye tissues: implications for glaucoma. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/15823551 Noladin ether acts on trabecular meshwork cannabinoid (CB1) receptors to enhance aqueous humor outflow facility. (full 2006) http://www.iovs.org/content/47/5/1999.long Effect of Sublingual Application of Cannabinoids on Intraocular Pressure
(abst - 2006)
Involvement of the Endocannabinoid System in Retinal Damage after High Intraocular PressureInduced Ischemia in Rats (full - 2007)
http://www.iovs.org/cgi/content/full/48/7/2997?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=can nabis&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT
Neuroprotective and Intraocular Pressure-Lowering Effects of (-)DeltaTetrahydrocannabinol in a Rat Model of Glaucoma. (abst - 2007)
http://www.unboundmedicine.com/medline/ebm/record/17284931/abstract/Neuroprotective_and_Intraocul ar_Pressure_Lowering_Effects_of____Delta_Tetrahydrocannabinol_in_a_Rat_Model_of_Glaucoma
Additive Effects of Timolol and Cannabinoids on Intraocular Pressure in a Rat Glaucoma Model (abst - 2007)
http://abstracts.iovs.org/cgi/content/abstract/48/5/4807?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=cannabinoid&searchid=1&FIRSTINDEX=560&resourcetype=HWCIT
Dronabinol and retinal hemodynamics in humans.
(abst - 2007)
339
N-arachidonylethanolamide-Induced Increase in Aqueous Humor Outflow Facility (full - 2008) http://www.iovs.org/cgi/content/full/49/10/4528 Mediation of Cannabidiol Anti-inflammation in the Retina by Equilibrative Nucleoside Transporter and A2A Adenosine Receptor (full 2008)
Topical WIN55212-2 Alleviates Intraocular Hypertension in Rats Through a CB1 Receptor-Mediated Mechanism of Action (full - 2008)
The role of endocannabinoid system in physiological and pathological processes in the eye (abst - 2008)
http://www.unboundmedicine.com/medline/ebm/record/19195174/abstract/%5BThe_role_of_endocannabi noid_system_in_physiological_and_pathological_processes_in_the_eye%5D
Alternative therapy in glaucoma management: Is there any role?

(full 2011)
Cannabinoid applications in glaucoma.
(abst 2011)
Effect of ion pairing on in vitro transcorneal permeability of a (9) -tetrahydrocannabinol prodrug: Potential in glaucoma therapy. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21989812/abstract/Effect_of_ion_pairing_on_in_vi tro_transcorneal_permeability_of_a_%CE%94_9___tetrahydrocannabinol_prodrug:_Potential_in_glaucom a_therapy_
Comparison Of Rat And Human Eyes For The Presence And Distribution Of Cb1 And Cb2 Receptors (abst - 2011)
Nonpsychotropic Cannabinoids, Abnormal Cannabidiol and Canabigerol-Dimethyl Heptyl, Act at Novel Cannabinoid Receptors to Reduce Intraocular Pressure. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21770780 January is Glaucoma Awareness Month: Can Marijuana save eyesight? (news / anecdotal 2011)
http://www.examiner.com/norml-in-madison/january-is-glaucoma-awareness-month-can-marijuana-saveeyesight
340
GOUT A Novel Intervention for the Treatment of Gout in an Elderly Rehabilitation Patient in Whom Conventional Treatment was Ineffective (full 2004)
http://www.medicine.virginia.edu/clinical/departments/physical-medicine-rehabilitation/Gout-page
A new one: HEALING OIL AND GOUT! My Pot Story: Gout and Medical Marijuana
(Forum thread/ anecdotal 2005) (news/ anecdotal 2011) (news/anecdotal 2011)
http://www.thc-ministry.org/forum/showthread.php?t=1374
http://californiapotblog.com/gout-marijuana-medicine-pot-story/
Is Medical Marijuana a Controllable Gout Solution?
http://articlesfair.com/business/health-care/is-medicinal-marijuana-a-controllable-gout-solution/
GRANULOMA Local administration of WIN 55,212-2 reduces chronic granuloma-associated angiogenesis in rat by inhibiting NF-kappaB activation. (abst 2007)
Cannabinoids reduce granuloma-associated angiogenesis in rats by controlling transcription and expression of mast cell protease-5. (full 2008)
Levels of endocannabinoids and palmitoylethanolamide and their pharmacological manipulation in chronic granulomatous inflammation in rats. (abst 2010)
Palmitoylethanolamide reduces granuloma-induced hyperalgesia by modulation of mast cell activation in rats (full 2011)
GRAVE'S DISEASE (overactive thyroid) Alternative Treatments for Graves Disease; Marijuana (Cannabis) (news - 2009)
http://mcsocal.com/blog/alternative-treatments-for-graves-disease-marijuana-cannabis/
341
GWP- 42006- a phytocannabinoid Cannabis could help treat epilepsy # 1 Cannabis could be used to treat epilepsy #2 (news 2011) (news 2011)
Pot Compound Exerts Anticonvulsant Effects In Animal Models Of Epilepsy (news - 2011) http://www.norml.org/index.cfm?Group_ID=8458
GYNOCOLOGY / FEMALE SEXUAL FUNCTION Women Find Healthy Hormone Balance with Hemp ( ad/ article - no date)
MIGRAINE ASSOCIATED WITH MENSTRUATION (article 1942 - on 3rd page)

http://jama.amaassn.org/cgi/reprint/120/4/324?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid= 1&FIRSTINDEX=320&resourcetype=HWCIT
Marihuana use across the menstrual cycle. (abst 1986)


(abst 1988)
Cannabis Treatments in Obstetrics and Gynecology: A Historical Review (full - 2002) http://www.cannabis-med.org/data/pdf/2002-03-04-1_0.pdf Female sex, but not male sex, better with cannabis (news 2009)
http://www.examiner.com/health-science-in-vancouver/female-sex-but-not-male-sex-better-with-cannabis
Antiproliferative effects of cannabinoid agonists on deep infiltrating endometriosis. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/21057002 Misdiagnosed chronic pelvic pain: pudendal neuralgia responding to a novel use of palmitoylethanolamide. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20345619
342
Effect of palmitoylethanolamide-polydatin combination on chronic pelvic pain associated with endometriosis: preliminary observations. (abst 2010)
Effects of the cannabinoid antagonist SR 141716 on sexual and motor behavior in receptive female rats. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21848907 San Francisco Medical Marijuana Clinic Says Cannabis is Effective for Many Womens Medical Issues (news 2011)
http://www.redorbit.com/news/health/2085616/san_francisco_medical_marijuana_clinic_says_cannabis_is _effective_for/index.html?source=r_health
Cannabis brings relief to women suffering from PMS and PMDD symptoms (news 2011)
http://www.examiner.com/cannabis-revolution-in-las-vegas/cannabis-brings-relief-to-women-sufferingfrom-pms-and-pmdd-symptoms
Cannabis and Women's Health Part 1: Historic Evidence
(news 2011)
http://www.examiner.com/medical-marijuana-in-philadelphia/cannabis-and-women-s-helath-part-1historic-evidence
My Green Valentine: Sex and marijuana
(news/interview 2011)
HAIR Inhibition of human hair follicle growth by endo and exocannabinoids (full - 2007)
http://www.fasebj.org/cgi/reprint/21/13/3534?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=cann abis&andorexactfulltext=and&searchid=1&FIRSTINDEX=10&sortspec=relevance&resourcetype=HWCIT
Identification of cannabinoid type 1 receptor in dog hair follicles. (abst 2011)

http://www.unboundmedicine.com/medline/ebm/record/21414652/abstract/Identification_of_cannabinoid_t ype_1_receptor_in_dog_hair_follicles_

HEADACHE - see MIGRAINE
343
HEARING - also see TINNITUS Effect of Marihuana on Hearing. (abst 1976)

The acute effects of tetrahydrocannabinol on auditory threshold and frequency resolution in human subjects. (abst - 2002) http://www.ncbi.nlm.nih.gov/pubmed/12195931 Doctor's diary: cannabis as medicine - the dilemma
(news - 2005)
Cannabinoid receptor down-regulation in the ventral cochlear nucleus in a salicylate model of tinnitus. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17376618 Mutations in ABHD12 Cause the Neurodegenerative Disease PHARC: An Inborn of Endocannabinoid Metabolism (full 2011)
Modulation of Auditory and Visual Processing by Delta-9-Tetrahydrocannabinol and Cannabidiol: an fMRI Study. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21412224 Association between a cannabinoid receptor gene (CNR1) polymorphism and cannabinoid-induced alterations of the auditory event-related P300 potential. (abst 2011)
HEART DISEASE/ CARDIOVASCULAR Effects of cannabis roots on the heart. (forum post- letter - 1973)
Intravenous delta9-Tetrahydrocannabinol: Effects of ventilatory control and cardiovascular dynamics. (full - 1975)
The Effects of Delta-9-Tetrahydrocannabinol (Cannabis) on Cardiac Performance with and without Beta Blockade (full - 1976)
http://circ.ahajournals.org/cgi/reprint/53/4/703?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=mar ihuana&searchid=1&FIRSTINDEX=2080&resourcetype=HWCIT
The cardiovascular effects of marihuana in man
(full - 1977)
http://chestjournal.chestpubs.org/content/72/1/2.full.pdf+html?maxtoshow=&hits=80&RESULTFORMAT =&fulltext=marihuana&searchid=1&FIRSTINDEX=80&resourcetype=HWCIT
344
Short-term effects of smoked marihuana on left ventricular function in man (full - 1977)
http://chestjournal.chestpubs.org/content/72/1/20.full.pdf+html?maxtoshow=&hits=80&RESULTFORMA T=&fulltext=cannabis&searchid=1&FIRSTINDEX=640&resourcetype=HWCIT
Propranolol Effects on Acute Marihuana Intoxication in Man.

(abst 1977)
(full - 1980)
Effects of acute marijuana smoking in post-menopausal women.

(abst 1986)
Changes in middle cerebral artery velocity after marijuana
(abst - 1992) (abst 1995)
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1420630&dopt=Abstract
Development of HU-211 as a neuroprotectant for ischemic brain damage.

(abst - 2000)
Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries (full - 2001) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573021/?tool=pmcentrez
345
Endogenous cannabinoid anandamide increases heart resistance to arrhythmogenic effects of epinephrine: role of CB(1) and CB(2) receptors. (abst - 2001)
Endocannabinoids are implicated in the infarct size-reducing effect conferred by heat stress preconditioning in isolated rat hearts. (full 2002)
http://cardiovascres.oxfordjournals.org/content/55/3/619.long
Increase of the heart arrhythmogenic resistance and decrease of the myocardial necrosis zone during activation of cannabinoid receptors (abst 2002)
Endogenous cannabinoids improve myocardial resistance to arrhythmogenic effects of coronary occlusion and reperfusion: a possible mechanism. (abst - 2002)
Endocannabinoids protect the rat isolated heart against ischaemia

(full - 2003)
Vasodilator actions of abnormal-cannabidiol in rat isolated small mesenteric artery (full - 2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573773/?tool=pmcentrez CB1 cannabinoid receptor antagonism promotes remodeling and cannabinoid treatment prevents endothelial dysfunction and hypotension in rats with myocardial infarction (full - 2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573770/?tool=pmcentrez Cannabinoid CB2 receptor activation reduces mouse myocardial ischemia-reperfusion injury: involvement of cytokine/chemokines and PMN (full - 2003)
A new endothelial target for cannabinoids.
(full - 2003)
346
Endocannabinoids as mediators in the heart: a potential target for therapy of remodelling after myocardial infarction? (full - 2003)
Cannabinoids prevented the development of heart failure in animal study

(news - 2003)
(news - 2003?) http://www.idmu.co.uk/canncardio.htm
The complexities of the cardiovascular actions of cannabinoids

(full - 2004)
(full - 2005)
Anandamide reduces infarct size in rat isolated hearts subjected to ischaemiareperfusion by a novel cannabinoid mechanism (full - 2005)
Effects of AM281, a cannabinoid antagonist, on systemic haemodynamics, internal carotid artery blood flow and mortality in septic shock in rats (full 2005)
The cardiovascular actions of anandamide: more targets?
(full - 2005) (abst - 2005)
Cardiac and vascular effects of cannabinoids: toward a therapeutic use?
CARDIOVASCULAR Effects of AM281, a cannabinoid antagonist, on systemic haemodynamics, internal carotid artery blood flow and mortality in septic shock in rats (abst 2005) http://academic.research.microsoft.com/Paper/11905213 Influence of Anandamide, the Endogenous Agonist of Cannabinoid Receptors on the Circulatory System (abst - 2005)
MEDICAL BIOLOGY: MARIJUANA AND THE HEART

http://scienceweek.com/2005/sw050617-5.htm
(news - 2005)
Marijuana Chemical Fights Hardened Arteries
(news - 2005)
http://www.webmd.com/heart-disease/news/20050406/marijuana-chemical-fights-hardened-arteries
347

(news - 2005)
Cannabis chemical 'helps heart'
(news - 2005) http://news.bbc.co.uk/2/hi/health/4417261.stm
Further Characterization of the Time-Dependent Vascular Effects of 9Tetrahydrocannabinol (full - 2006) http://jpet.aspetjournals.org/content/317/1/428.full Illicit Drug Use in Young Adults and Subsequent Decline in General Health: The Coronary Artery Risk Development in Young Adults (CARDIA) Study (full - 2006)
Signaling pathways involved in the cardioprotective effects of cannabinoids. (full - 2006) http://www.jstage.jst.go.jp/article/jphs/102/2/155/_pdf The endogenous cardiac cannabinoid system: a new protective mechanism against myocardial ischemia. (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16618028 Delta-9-tetrahydrocannabinol protects cardiac cells from hypoxia via CB2 receptor activation and nitric oxide production (abst - 2006)
http://www.ingentaconnect.com/content/klu/mcbi/2006/00000283/F0020001/00002346

(full - 2006) (abst - 2006)
Marijuana use, diet, body mass index, and cardiovascular risk factors
Cannabis use not associated with risk factors for diseases of heart and circulation (news - 2006)
THC protects heart cells in the case of lowered oxygen supply Cannabinoid Offers Cardioprotection (news - 2006)
(news - 2006)
Heavy Cannabis Use Not Independently Associated With Cardiovascular Risks (news - 2006) http://www.norml.org/index.cfm?Group_ID=6972 The in vitro and in vivo cardiovascular effects of {Delta}9-tetrahydrocannabinol (THC) in rats made hypertensive by chronic inhibition of nitric oxide synthase. (full - 2007)
Characterization of the vasorelaxant mechanisms of the endocannabinoid anandamide in rat aorta (full 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190007/?tool=pubmed
348
The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects. (full - 2007)
Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats (full - 2007)
Endocannabinoids and the haematological system
(full - 2007)
Cannabinoids and cardiovascular disease: a tale of passions and illusions. (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2013961/?tool=pubmed Cannabidiol , a nonpsychoactive Cannabis constituent, protects against myocardial ischemic reperfusion injury. (full - 2007)
http://ajpheart.physiology.org/cgi/content/full/293/6/H3602
Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190006/?tool=pmcentrez Cannabinoids and cardiovascular disease: the outlook for clinical treatments. (abst - 2007)
http://www.ncbi.nlm.nih.gov/pubmed/17627561?ordinalpos=1&itool=PPMCLayout.PPMCAppController. PPMCArticlePage.PPMCPubmedRA&linkpos=5
Cannabinoids as therapeutic agents in cardiovascular disease
(abst - 2007)
http://www.unboundmedicine.com/medline/ebm/record/17450170/abstract/Cannabinoids_as_therapeutic_a gents_in_cardiovascular_disease:_a_tale_of_passions_and_illusions
Cannabinoid receptors in acute and chronic complications of atherosclerosis (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219535/?tool=pmcentrez THE ENDOCANNABINOID SYSTEM AND CARDIOVASCULAR DISEASE Introduction (full - 2008)
http://www.docstoc.com/docs/33739226/THE-ENDOCANNABINOID-SYSTEM-ANDCARDIOVASCULAR-DISEASE-Introduction
Endocannabinoids and Liver Disease. V. Endocannabinoids as mediators of vascular and cardiac abnormalities in cirrhosis (full 2008)
http://ajpgi.physiology.org/content/295/4/G649.full?sid=c16d770d-cd17-48c9-bbde-26f38f5eeb67
CB1 Cannabinoid Receptor Inhibition: Promising Approach for Heart Failure? (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669829/?tool=pmcentrez
349
Modulation of the Endocannabinoid System in Cardiovascular Disease (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568884/?tool=pmcentrez Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats (full - 2008)
Endocannabinoids, blood pressure and the human heart. Function of cannabinoids in heart failure
http://www.phmd.pl/fulltxt.php?ICID=856842
(full - 2008).
(full - 2008) (full - 2008)
The endocannabinoid system: an osteopathic perspective.

http://www.jaoa.org/cgi/content/full/108/10/586
Dexanabinol prevents development of vasospasm in the rat femoral artery model. (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/18256864 Rimonabant doesn't reduce heart risk Endocannabinoids and the Heart (news - 2008)
http://www.healthandage.com/Rimonabant-doesnt-reduce-heart-risk
(full - 2009)
The emerging role of the endocannabinoid system in cardiovascular disease (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791499/?tool=pmcentrez Endocannabinoids and cardiac contractile function: pathophysiological implications. (full 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768548/?tool=pubmed Time-dependent vascular actions of cannabidiol in the rat aorta.
(abst 2009)
Cannabidiol Attenuates Myocardial Dysfunction, Fibrosis, Inflammation, Cell Death and Interrelated Signaling Pathways Associated With Diabetic Cardiomyopathy (abst - 2009)
http://circ.ahajournals.org/cgi/content/meeting_abstract/120/18_MeetingAbstracts/S868?maxtoshow=&hits =80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1680&resourcetype=HWC IT
Endocannabinoids and cardiovascular prevention: real progress?

(abst - 2009)
350
CB2 cannabinoid receptor activation is cardioprotective in a mouse model of ischemia/reperfusion (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19162037 Cannabinoids and atherosclerosis. (abst - 2009)
Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion. (full 2010)
The cardiac and haemostatic effects of dietary hempseed.

http://www.nutritionandmetabolism.com/content/pdf/1743-7075-7-32.pdf
(full - 2010) (full - 2010)

US Patent Application 20100158973 - THERAPEUTIC USES OF CANNABIDIOL COMPOUNDS (full 2010) http://www.patentstorm.us/applications/20100158973/fulltext.html Substantially altered expression pattern of cannabinoid receptor 2 and activated endocannabinoid system in patients with severe heart failure. (abst 2010)
Pharmacologically induced hypothermia with cannabinoid receptor agonist WIN55, 2122 after cardiopulmonary resuscitation (abst 2010)
Interaction between anandamide and sphingosine-1-phosphate in mediating vasorelaxation in rat coronary artery (abst 2010)
Lab Notes: Pot Has Benefits for Diabetic Hearts

(news - 2010) (news 2010)
Inhaled Incense "K2" May Cause Heart Damage
http://drwes.blogspot.com/2010/08/inhaled-incense-k2-may-cause-heart.html
351

(news - 2010)
The potential for clinical use of cannabinoids in treatment of cardiovascular diseases. (full 2011) http://onlinelibrary.wiley.com/doi/10.1111/j.1755-5922.2010.00233.x/pdf Endocannabinoid system in cardiovascular disorders - new pharmacotherapeutic opportunities (full 2011)
Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion (full 2011)
Cannabidiol as an anti-arrhythmic, the role of the CB1 receptors.
(abst 2011)
Distinctive effects of plant protein sources on renal disease progression and associated cardiac hypertrophy in experimental kidney disease. (abst 2011)
Deficiency of type 1 cannabinoid receptors worsens acute heart failure induced by pressure overload in mice. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21785110 The effects of hempseed meal intake and linoleic acid on Drosophila models of neurodegenerative diseases and hypercholesterolemia. (abst 2011)
Effect of substance abuse on defibrillation threshold in patients with implantable cardioverter-defibrillator. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/20946279 Endocannabinoids and the cardiovascular response to stress.
(abst - 2011)
Cardiotoxicity associated with the synthetic cannabinoid, K9, with laboratory confirmation. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21802885 Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress. (abst 2011)
352
The effect of dietary hempseed on atherogenesis and contractile function in aortae from hypercholesterolemic rabbits. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21893466 Targeting the Endocannabinod System to Limit Myocardial and Cerebral Ischemic and Reperfusion Injury. (abst 2011)
Cannabidiol (CBD) as an Anti-Arrhythmic (abst 2011)

Marijuana Compounds Hold Promise In Treatment Of Cardiovascular Diseases (news 2011) http://www.norml.org/index.cfm?Group_ID=8466
HEMORRHAGIC SHOCK Pharmacokinetics of a combination of 9-tetrahydro-cannabinol and celecoxib in a porcine model of hemorrhagic shock. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21341278/abstract/Pharmacokinetics_of_a_combin ation_of_%CE%949_tetrahydro_cannabinol_and_celecoxib_in_a_porcine_model_of_hemorrhagic_shock_
Low-volume binary drug therapy for the treatment of hypovolemia.
(abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21330941/abstract/Low_volume_binary_drug_ther apy_for_the_treatment_of_hypovolemia_
HEPATITIS A Novel Synthetic Cannabinoid Derivative Inhibits Inflammatory Liver Damage via Negative Cytokine Regulation (full - 2003)
http://molpharm.aspetjournals.org/content/64/6/1334.full
The endocannabinoid system in chronic liver disease

http://www.medigraphic.com/pdfs/hepato/ah-2005/ah054c.pdf
(full - 2005) (full - 2005) (abst 2005)
(Marijuana/Hash) Endocannabinoids and liver disease - review

http://www.natap.org/2005/HCV/091905_01.htm
Antifibrogenic role of the cannabinoid receptor CB2 in the liver.

353
Cannabis use improves retention and virological outcomes in patients treated for hepatitis C (full - 2006) http://www.natap.org/2006/HCV/091506_02.htm Study: Pot Helps Hepatitis Treatment (news - 2006)
http://www.thehempire.com/index.php/cannabis/news/study_pot_helps_hepatitis_treatment
Attenuation of Experimental Autoimmune Hepatitis by Exogenous and Endogenous Cannabinoids : Involvement of Regulatory T Cells (full - 2008)
Evaluation of oral cannabinoid-containing medications for the management of interferon and ribavirin-induced anorexia, nausea and weight loss in patients treated for chronic hepatitis C virus. (full - 2008)
Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects (abst - 2008) http://gut.bmj.com/content/57/8/1140.abstract Endocannabinoids in liver disease and hepatic encephalopathy.
(abst 2008)
Should Hepatitis C Patients Who Smoke Marijuana Be Eligible For Liver Transplants? (news - 2008) http://www.sciencedaily.com/releases/2008/10/081022211032.htm Cannabinoids as novel anti-inflammatory drugs. (full - 2009)
US Patent Application 20090005461 - Use of Cannabidiol in the Treatment of Hepatitis (full 2009) http://www.patentstorm.us/applications/20090005461/fulltext.html The role of CB2 cannabinoid receptor and Leptin in hepatic fibrosis via lymphocyte alterations and HSC phagocytosis (abst 2009)
Use of Cannabinoids as a Novel Therapeutic Modality Against Autoimmune Hepatitis (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19647124 Endocannabinoids in liver disease. (full 2011)
354
Role of Myeloid-Derived Suppressor Cells in Amelioration of Experimental Autoimmune Hepatitis Following Activation of TRPV1 Receptors by Cannabidiol (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069975/?tool=pmcentrez Cannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis. (full 2011)
Cannabis Compound Induces Death Of Cells Associated With Liver Fibrosis (news 2011) http://www.norml.org/index.cfm?Group_ID=8615
HEREDITARY MULTIPLE EXTOSES Chronic Cannabis Use in the Compassionate Investigational New Drug Program: An Examination of Benefits and Adverse Effects of Legal Clinical Cannabis (full 2002) http://proxy.baremetal.com/cannabiscoalition.ca/chronic.pdf
HERPES VIRUS The Effect of {Delta}-9-Tetrahydrocannabinol on Herpes Simplex Virus Replication (full - 1980) http://vir.sgmjournals.org/cgi/content/abstract/49/2/427 Suppressive effect of delta-9-tetrahydrocannabinol on herpes simplex virus infectivity in vitro (abst - 1991) http://www.ncbi.nlm.nih.gov/pubmed/1848937?dopt=Abstract THC inhibits lytic replication of gamma oncogenic herpes viruses in vitro
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=521080
(full - 2004)
Cannabis May Help Combat Cancer-causing Herpes Viruses

(news - 2004)
THC in marijuana may block the spread of forms of cancer causing herpes viruses (news - 2004) http://www.news-medical.net/news/2004/09/22/4990.aspx Screening for Antiviral Activities of Isolated Compounds from Essential Oils (full - 2009)
http://ecam.oxfordjournals.org/cgi/content/full/nep187v1?maxtoshow=&hits=10&RESULTFORMAT=&fu lltext=Beta-caryophyllene+&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
355
Adjuvant topical therapy with a cannabinoid receptor agonist in facial postherpetic neuralgia. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19744255
HEXAHYDROCANNABINOLS - synthetic cannabinoid derivatives Hexahydrocannabinols, novel synthetic cannabinoid derivatives, suppress the tumor growth by inhibiting the VEGF secretion and angiogenesis (abst - 2009)
http://www.fasebj.org/cgi/content/meeting_abstract/23/1_MeetingAbstracts/761.3?maxtoshow=&hits=10& RESULTFORMAT=&fulltext=cannabis&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspe c=relevance&resourcetype=HWCIT
Involvement of NSAID-activated gene-1 in a novel synthetic hexahydrocannabinol analogue-induced growth inhibition and apoptosis of colon cancer cells (abst - 2010)
Induction of p53-independent apoptosis by a novel synthetic hexahydrocannabinol analog is mediated via Sp1-dependent NSAID-activated gene-1 in colon cancer cells (abst - 2010)
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T4P-4YM7FF02&_user=10&_coverDate=07%2F01%2F2010&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor =&view=c&_searchStrId=1313682160&_rerunOrigin=scholar.google&_acct=C000050221&_version=1& _urlVersion=0&_userid=10&md5=6f222e32968fcf27444674d5217dcecb
Novel hexahydrocannabinol analogs as potential anti-cancer agents inhibit cell proliferation and tumor angiogenesis. (abst 2011)
HICCUPS Marijuana For Intractable Hiccups Marijuana cures hiccups (abst -1998)
http://cannabislink.ca/medical/hiccups.html
(news - 1998)
http://www.yourhealthbase.com/database/a77k.htm
Cannabinoids suppress synaptic input to neurones of the rat dorsal motor nucleus of the vagus nerve (full 2004) http://jp.physoc.org/content/559/3/923.full#sec-19
356
HISTORICAL STUDIES - PRE 1937 Observations on the raising and dressing of hemp (1789) As text- http://memory.loc.gov/cgi-bin/query/r?ammem/faw:@field(DOCID+icufawcbc0010) Observations on the raising and dressing of hemp (1789) Original format- http://memory.loc.gov/cgi-bin/ampage ON THE PREPARATIONS OF THE INDIAN HEMP, OR GUNJAH (1839)
http://www.druglibrary.org/schaffer/history/e1850/gunjah.htm
DISPENSATORY OF THE UNITED STATES OF AMERICA Fifth Edition (1843)

http://www.druglibrary.org/schaffer/hemp/history/dispensa.htm
On the Preparations of the Indian Hemp, or gunjah* Cannabis Indica Their Effects on the Animal System in Health, and their Utility in the Treatment of Tetanus and other Convulsive Diseases (1843)
New Remedies:Pharmaceutically and Therapeutically Considered Fourth Edition (1843)

http://www.druglibrary.org/schaffer/hemp/history/dunglisn.htm
Observations on the medicinal properties of the Cannabis Sativa of India

(1843)
Observations on the Cannabis Indica, or Indian Hemp
(1843)
On Traumatic Tetanus and Its Treatment, with Some Remarks on the Extract of Cannabis Indica of Commerce (1845)
Case of Traumatic Tetanus Exhibition of the Extract of Indian Hemp (Cannabis Indica)DeathAutopsy (1845)
A Case of Dysmenorrha in Which the Tincture of Cannabis Indica Was Employed, with Some Observations upon That Drug (1847)
On the Haschisch or Cannabis Indica
(1857) (1860)
http://www.druglibrary.org/schaffer/hemp/history/bellhash.htm
Report of the Ohio State Medical Committee on Cannabis Indica

On the Action of Cannabis Indica
(1883)
357
Cannabis Indica (1883)

Clinical and Physiological Notes on the Action of Cannabis Indica

(1887)
The Use of Indian Hemp in the Treatment of Chronic Chloral and Chronic Opium Poisoning (1889) http://www.onlinepot.org/medical/Dr_Tods_PDFs/s3_2.pdf Therapeutical Uses and Toxic Effects of Cannabis Indica (1890)
Cannabis Indica as an Anodyne and Hypnotic (1891)

Physical, Mental, and Moral Effects of Marijuana: The Indian Hemp Drugs Commission Report (1894) http://www.druglibrary.org/schaffer/Library/effects.htm A Practical treatise on nervous exhaustion(neurasthenia) aka Chronic Fatigue Syndrome (full 1894)
http://www.scribd.com/doc/49652565/Chronic-Fatigue-Syndrome-Cannabis-Treatment-1894
Cannabis Sativa Seu Indica: Indian Hemp
(1895) (1898)
Cannabis Indica (U. S. P.)Indian Cannabis. King's American Dispensatory,

http://www.henriettesherbal.com/eclectic/kings/cannabis.html
A Contribution to the Pharmacology of Cannabis Indica

(1898)
Cannabis Indica Poisoning
(1899)
Two cases of Poisoning by Cannabis Indica
(1900)
ON INDICATIONS OF THE HACHISH-VICE IN THE OLD TESTAMENT (1903)

http://www.druglibrary.org/schaffer/hemp/history/hashot.htm
A British Study of Cannabis
(Circa 1910)
http://www.ukcia.org/research/red-eye.php
An Essay on Hasheesh: Historical and Experimental

http://www.lycaeum.org/~sputnik/Ludlow/Texts/essay.html
(1912)
Ganja in Jamaica : Appendix I - Ganja Smoking as a Danger to the Natives of this Colony- editorial 1913) (book 1976)
http://www.cifas.us/cannabis/PDFs/OCRGanjainJamaica.pdf
358
The Physiological Activity of Cannabis Sativa

http://www.druglibrary.org/schaffer/hemp/history/japa.htm
(1913) (1918)
The Dispensatory of the United States of America CANNABIS. U.S. (Br.)

Narcotic Control in the State of Washington
(1923)
http://jama.amaassn.org/cgi/reprint/80/18/1335?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid =1&FIRSTINDEX=3200&resourcetype=HWCIT
CANNABIS, U.S.P. (American Cannabis):
(1929)
http://www.druglibrary.org/schaffer/hemp/history/vbchmed1.htm
Effects of Alcohol and Cannabis during Labor. (1930) (on page 2)

http://jama.ama-assn.org/cgi/reprint/94/15/1164a?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid=1&FIRSTINDEX=3360&res ourcetype=HWCIT
MARIAJUANA SMOKING IN PANAMA The British Pharmaceutical Codex MARIHUANA INTOXICATION (1934) (1934)
(1933)
http://www.druglibrary.org/schaffer/Library/studies/panama/panama1.htm
http://www.druglibrary.org/schaffer/hemp/medical/brit34.htm
http://ajp.psychiatryonline.org/cgi/content/abstract/91/2/303?maxtoshow=&hits=80&RESULTFORMAT= &fulltext=marihuana&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
TIME FACTOR IN UTILIZATION OF MINERAL NUTRIENTS BY HEMP by Sister Mary Etienne Tibeau (1936)
American Medical Association Opposes the Marijuana Tax Act of 1937

http://www.marijuanalibrary.org/AMA_opposes_1937.html
(1937)
Cannabis Condemned: the Proscription of Indian Hemp. The Emperor Wears No Clothes (book - 2007) THE ANTIQUE CANNABIS BOOK
(abst 2003)
http://medical-journals.healia.com/doc/12534418/Cannabis-condemned-the-proscription-of-Indian-hemp http://www.jackherer.com/thebook/ http://antiquecannabisbook.com/
(full - 2010)
359
HISTORY - ANCIENT USE Marijuna Through History (news - no date) (news- no date)
Ancient Psychoactive Incense and Preparations

Ayurvedic Herbs Cannabis
(article no date) (full - 1955)
http://www.indianmirror.com/ayurveda/cannabis.html
HEMP AS A MEDICAMENT : History of the medicinal use of hemp

Pharmacy in medieval Islam and the history of drug addiction.
(full - 1972)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1034978/pdf/medhist00126-0026.pdf
EARLY DIFFUSION AND FOLK USES OF HEMP (full 1975)

http://khem-caigan.livejournal.com/3259.html
The Religious and Medicinal Uses of Cannabis in China, India and Tibet
http://www.cnsproductions.com/pdf/Touw.pdf
(full - 1981)
Hashish in Islam 9th to 18th century. (full - 1982)

Hashish and drug abuse in Egypt during the 19th and 20th centuries.
(full -1985)
Thandai and chilam: traditional Hindu beliefs about the proper uses of Cannabis. (abst 1985) http://www.ncbi.nlm.nih.gov/pubmed/3903086 SCIENCE WATCH; Marijuana Medication (news 1993) (abst 1998)
http://www.nytimes.com/1993/06/01/science/science-watch-marijuana-medication.html?src=pm

Cannabis in Traditional Indian Herbal Medicine

http://www.ucl.ac.uk/~ucgadkw/papers/cannabis.pdf
(full - 2001) (full 2001) (full - 2002)
The Therapeutic Use of Cannabis sativa (L.) in Arabic Medicine

http://www.cannabis-med.org/data/pdf/2001-01-4_0.pdf
The Medical Use of Cannabis Among the Greeks and Romans

The Unconstitutional Prohibition of Cannabis

http://www.icmag.com/ic/showthread.php?t=72908
(forum post- full- 2002?)
360
Jesus Healed Using Cannabis
(news - 2003)
Indigenous Uses and Ethnobotany of Cannabis sativa L. (Hemp) in Uttaranchal (India) (abst - 2004)
http://www.informaworld.com/smpp/content~db=all?content=10.1300/J237v09n01_07
Cannabis in India: ancient lore and modern medicine History of cannabis as a medicine: a review
(full - 2005)
http://www.drugpolicy.org/docUploads/Russo_CannabisInIndia_Mechoulam2005.pdf
(full - 2006)
ganja and Ayurveda
(article - 2006)
http://tribes.tribe.net/adi_ayurveda/thread/8f985241-54c5-4969-b8cb-f2923532ff9c
The Emperor Wears No Clothes (book - 2007) http://www.jackherer.com/thebook/ Phytochemical and genetic analyses of ancient cannabis from Central Asia (full - 2008) http://jxb.oxfordjournals.org/cgi/content/full/59/15/4171 Ancient cannabis stash unearthed in China THE ANTIQUE CANNABIS BOOK Ancient Egypt and Cannabis (news - 2008)
http://www.cnn.com/2008/WORLD/asiapcf/12/11/ancient.cannabis/index.html?iref=allsearch
( full - 2010) http://antiquecannabisbook.com/
(news 2011) (news 2011)
http://www.examiner.com/medical-marijuana-in-philadelphia/ancient-egypt-and-cannabis
Cannabis and Women's Health Part 1: Historic Evidence
http://www.examiner.com/medical-marijuana-in-philadelphia/cannabis-and-women-s-helath-part-1historic-evidence
HISTORY - 1937 to present The active principles of Cannabis indica resin. I. (full - 1938)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1264344/pdf/biochemj01029-0136.pdf
THE RELATIVE ACTIVITY OF VARIOUS PURIFIED PRODUCTS OBTAINED FROM AMERICAN GROWN HASHISH (abst - 1938)
http://jpet.aspetjournals.org/content/62/2/239.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabis&searchid=1&FIRSTINDEX=640&resourcetype=HWCIT
361
Description of the Hashish Experience Marihuana: America's New Drug Problem
(1938) (1939)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1529489/pdf/amjphnation00993-0104.pdf/?tool=pmcentrez
The Active Principles of Cannabis and the Pharmacology of the Cannabinols (full - 1940) http://www.ukcia.org/research/TherapeuticPotentialMedicalUses.php Marijuana (1942)
The La Guardia Committee Report The Marihuana Problem (1944)
(1944)
http://www.druglibrary.org/schaffer/Library/studies/lag/lagmenu.htm
http://jama.ama-assn.org/cgi/reprint/125/8/594a?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid=1&FIRSTINDEX=80&resou rcetype=HWCIT
PERSONALITY STUDIES OF MARIHUANA ADDICTS
(1945)
http://ajp.psychiatryonline.org/cgi/content/abstract/102/5/674?maxtoshow=&hits=80&RESULTFORMAT =&fulltext=marihuana&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
MARIHUANA, AN INTOXICANT
(1945)
MARIHUANA AND AGGRESSIVE CRIME
(1946)
Anti-epileptic Action of Marijuana-Active Substances

(full - 1949)
Becoming a Marihuana User
(full 1950) (1969)
http://joshpackard.files.wordpress.com/2008/09/becker-1953-marihuana-user.pdf
Marijuana in medicine: past, present and future. The marijuana problem. (full 1971)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1501871/pdf/califmed00136-0087.pdf
Survey of adolescent drug use. I. Sex and grade distribution. Untoward effects of drug education. (full 1973)
(full 1971)
362
Marihuana and drug abuse. Recommendations of the Committee on Public Health, New York Academy of Medicine. (full - 1973)
Paraquat and marijuana: epidemiologic risk assessment.
(full - 1978) (abst 1978)
Detection and analysis of paraquat in confiscated marijuana samples.

MARIJUANA RESCHEDULING PETITION RULING- JUDGE FRANCIS L. YOUNG (full 1988) http://www.druglibrary.org/SCHAFFER/Library/studies/YOUNG/index.html Physicians' attitudes toward the legalization of marijuana use. (full 1989)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1026731/pdf/westjmed00130-0092.pdf
A Comparative Appraisal of the Health and Psychological Consequences of Alcohol, Cannabis, Nicotine and Opiate Use (full 1995)
http://www.druglibrary.org/SCHAFFER/hemp/general/who-index.htm
Workshop on the Medical Utility of Marijuana
(full - 1997) (full 1998)
http://www.nih.gov/news/medmarijuana/MedicalMarijuana.htm
Cannabis as medicine: time for the phoenix to rise?
Cannabis Report of the Swiss Federal Commission For Drug Issues (EKDF) (full - 1999) http://www.ukcia.org/research/ekdf.pdf MARIJUANA AND MEDICINE: ASSESSING THE SCIENCE BASE (full 1999) http://www.druglibrary.org/SCHAFFER/Library/studies/iom/IOMReport.htm Cannabis: Time for Scientific Evaluation of This Ancient Remedy? (full - 2000)
A REPORT OF THE NATIONAL COMMISSION ON GANJA TO Rt. Hon. P.J. PATTERSON, Q.C., M.P. PRIME MINISTER OF JAMAICA (full - 2001)
http://www.ukcia.org/research/JamaicanNationalCommissionOnGanjaReport.pdf
Chronic Cannabis Use in the Compassionate Investigational New Drug Program: An Examination of Benefits and Adverse Effects of Legal Clinical Cannabis (full 2002) http://proxy.baremetal.com/cannabiscoalition.ca/chronic.pdf The Unconstitutional Prohibition of Cannabis
(as a forum post- full- 2002?)
363
Medicinal use of cannabis in the United States: Historical perspectives, current trends, and future directions (full - 2003)
http://www.whyprohibition.ca/sites/default/files/JOM_Aggarwal_Cannabis_Medical_33_studies.pdf
Cannabinoid pharmacology: the first 66 years Marijauna Production in the United States
(full - 2006) (full 2006)
http://www.drugscience.org/Archive/bcr2/MJCropReport_2006.pdf
The war on marijuana: The transformation of the war on drugs in the 1990s (full - 2006) http://www.harmreductionjournal.com/content/3/1/6 The Emperor Wears No Clothes (book - 2007)
http://www.jackherer.com/thebook/
History of Cannabis and Its Preparations in Saga, Science and Sobriquet

http://www3.interscience.wiley.com/cgi-bin/fulltext/115806128/PDFSTART
(full - 2007)
Retail marijuana purchases in designer and commercial markets in New York City: sales units, weights, and prices per gram. (full 2007)
Medi-Cal pays pot-related expenses
(news 2007)
http://www.pressdemocrat.com/article/20070707/NEWS/707070324?Title=Medi-Cal-pays-pot-relatedexpenses
Medical Marijuana Use and Research Leukemia & Lymphoma Society Statement (full 2008) http://www.maps.org/mmj/lnls-res.pdf Op-Ed: US Government Holds Patent For Medical Marijuana, Shows Hypocrisy (news 2008) http://www.digitaljournal.com/article/257008 Mexico decriminalizes small-scale drug possession.
(abst 2009)
http://antiquecannabisbook.com/
THE ANTIQUE CANNABIS BOOK
( full - 2010)
V.A. Easing Rules for Users of Medical Marijuana
(news 2010) (news 2010)
http://www.nytimes.com/2010/07/24/health/policy/24veterans.html
UC studies show marijuana has therapeutic value, reports to legislature

Global Commission Drug Report
(links to full, various languages 2011)
http://www.globalcommissionondrugs.org/Report
Reported value of cannabis seizures in Australian newspapers: are they accurate? (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21219493
364
Popular intoxicants: what lessons can be learned from the last 40 years of alcohol and cannabis regulation? (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21926420 How well do international drug conventions protect public health? (abst- register free for full 2011)
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2811%2961423-2/fulltext
Guide to California's Marijuana Laws (news 2011) http://www.canorml.org/camjlaws.html Worth Repeating: You Cant Censor Cannabis Cancer Treatment (news 2011)
http://www.tokeofthetown.com/2011/03/worth_repeating_you_cant_censor_cannabis_cancer_tr.php#more
Legalizing Medical Marijuana Does Not Increase Use Among Youth, Study Suggests (news - 2011) http://www.sciencedaily.com/releases/2011/11/111102161047.htm Medical marijuana laws in 50 states: Investigating the relationship between state legalization of medical marijuana and marijuana use, abuse and dependence. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/22099393
HIV / AIDS Recent clinical experience with dronabinol. (abst - 1991) (abst - 1992)


(abst - 1992) (abst - 1993)
Dronabinol as a treatment for anorexia associated with weight loss in patients with AIDS. (abst - 1995) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=21 Therapeutic Aspects of Cannabis and Cannabinoids
(full - 2001)
Summaries for patients. Does marijuana affect viral loads in people with HIV? (full - 2003) http://www.annals.org/content/139/4/I-44.long Short-term effects of cannabinoids in patients with HIV-1 infection
http://www.annals.org/content/139/4/258.full.pdf+html
(full - 2003)
365
US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants

(full - 2003)
(full - 2003) http://brain.oxfordjournals.org/cgi/content/full/126/6/1252 (abst - 2003) (summary 2003) (full - 2004)

Does Marijuana Affect Viral Loads in People with HIV? Cannabis Use in HIV for Pain and Other Medical Symptoms
http://www.jpsmjournal.com/article/S0885-3924(05)00063-1/fulltext
http://m.annals.org/content/139/4/I-44.full?sid=666743b8-7582-4176-be2d-c1773c46b1c2
Marijuana Use Does Not Accelerate HIV Infection

http://paktribune.com/news/print.php?id=139255
(news - 2004)
Marijuana and AIDS: A Four-Year Study (full - 2005)

http://ccrmg.org/journal/05spr/aids.html
Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation (full - 2005) http://www.jneuroinflammation.com/content/2/1/29 Smoked cannabis therapy for HIV-related painful peripheral neuropathy
(abst - 2005)
Cannabis: Use in HIV for Pain and Other Medical Symptoms

(abst - 2005)


(abst - 2007)
Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep. (abst - 2007)
Cannabis in painful HIV-associated sensory neuropathy
(abst - 2007)
Marijuana as therapy for people living with HIV/AIDS: Social and health aspects (abst - 2007)
http://www.unboundmedicine.com/medline/ebm/record/17364413/abstract/Marijuana_as_therapy_for_peo ple_living_with_HIV/AIDS:_Social_and_health_aspects
366
Cannabis may be safe and effective for HIV-related neuropathic pain

http://www.aidsmap.com/en/news/E0578F66-B327-4504-836D-DEE790B87A0F.asp
(news - 2007) (news 2007)
Marijuana, Very Efficient in Cutting Off HIV Related Nerve Pain
http://news.softpedia.com/news/Marijuana-Very-Efficient-in-Cutting-off-HIV-Related-Nerve-Pain47003.shtml
Smoked Cannabis Reduces Foot Pain Associated With HIV In Placebo Trial (news - 2007) http://www.sciencedaily.com/releases/2007/02/070212185335.htm Marijuana gives relief from chronic pain for AIDS sufferers
(news - 2007)
Recreational Drug Use and T Lymphocyte Subpopulations in HIV-uninfected and HIVinfected Men (full - 2008)
Smoked Medicinal Cannabis for Neuropathic Pain in HIV: A Randomized, Crossover Clinical Trial (full - 2008)

(full - 2008)
Denbinobin, a naturally occurring 1,4-phenanthrenequinone, inhibits HIV-1 replication through an NF-kappaB-dependent pathway. (abst - 2008)
Marijuana Effectiveness as an HIV Self-Care Strategy

http://cnr.sagepub.com/cgi/content/abstract/18/2/172
(abst - 2009)
Recreational Drug Use and Risk of Kaposi's Sarcoma in HIV- and HHV-8-Coinfected Homosexual Men (abst - 2009)
http://www.liebertonline.com/doi/abs/10.1089/aid.2008.0196?prevSearch=allfield%253A%2528cannabinoi d%2529&searchHistoryKey=
Marijuana Rivals Mainstream Drugs For Alleviating HIV/AIDS Symptoms (news - 2009) http://www.sciencedaily.com/releases/2009/05/090529081627.htm Pharmacological Treatment of Painful HIV-Associated Sensory Neuropathy: A Systematic Review and Meta-Analysis of Randomised Controlled Trials (full 2010)
367
Cannabinoids and Viral Infections
(full - 2010)
Cannabinoid Administration Attenuates the Progression of Simian Immunodeficiency Virus (full - 2010) http://www.liebertonline.com/doi/full/10.1089/aid.2010.0218 Cannabinoid inhibition of macrophage migration to the trans-activating (Tat) protein of HIV-1 is linked to the CB(2) cannabinoid receptor. (full 2010)
Chronic cannabinoid administration lowers viral replication in lymph nodes of SIV infected Rhesus macaques (abst - 2010)
http://www.fasebj.org/cgi/content/meeting_abstract/24/1_MeetingAbstracts/752.6?maxtoshow=&hits=80& RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=720&resourcetype=HWCIT
The endocannabinoid system in gp120-mediated insults and HIV-associated dementia. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20353779 Marijuana Use is Not Associated with Cervical Human Papillomavirus Natural History or Cervical Neoplasia in HIV-Seropositive or HIV-Seronegative Women (abst - 2010)
http://cebp.aacrjournals.org/content/19/3/869.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabinoid&searchid=1&FIRSTINDEX=2960&resourcetype=HWCIT
Efficacy and tolerability of high-dose dronabinol maintenance in HIV-positive marijuana smokers: a controlled laboratory study. (abst 2010)
THC Keeps Monkeys Alive in AIDS Research Model
(news - 2010)
http://cannabination.com/2010/10/23/thc-keeps-monkeys-alive-in-aids-research-model/
Activation of CB2 Cannabinoid Receptors Inhibits HIV-1 Envelope Glycoprotein gp120Induced Synapse Loss. (full 2011)
Tolerance to chronic delta-9-tetrahydrocannabinol (-THC) in rhesus macaques infected with simian immunodeficiency virus. (full 2011)
Tolerance to chronic delta-9-tetrahydrocannabinol (-THC) in rhesus macaques infected with simian immunodeficiency virus. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21463073/abstract/Tolerance_to_chronic_delta_9_ tetrahydrocannabinol__%CE%94%E2%81%B9_THC__in_rhesus_macaques_infected_with_simian_immu nodeficiency_virus_
Cannabinoid Neuroimmune Modulation of SIV Disease.

(abst 2011)
Immunomodulatory properties of kappa opioids and synthetic cannabinoids in HIV-1 neuropathogenesis. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21850403
368
HIV-1 infection and alcohol abuse: neurocognitive impairment, mechanisms of neurodegeneration and therapeutic interventions. (abst 2011)
Cannabinoids Inhibit Migration of Microglial-like Cells to the HIV Protein Tat. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21735070 Cannabinoid Administration Halts Disease Progression, Decreases Mortality In Primate Version of Human Immunodeficiency Virus (HIV) (news 2011)
http://blog.norml.org/2011/06/14/cannabinoid-administration-halts-disease-progression-decreasesmortality-in-primate-version-of-human-immunodeficiency-virus-hiv/
A pilot study of the effects of cannabis on appetite hormones in HIV-infected adult men. (abst 2012)
http://www.unboundmedicine.com/medline/ebm/record/22133305/abstract/A_pilot_study_of_the_effects_o f_cannabis_on_appetite_hormones_in_HIV_infected_adult_men_
HORMONES Hemp Packs in Powerful Source of Preconception Nutrition (article - no date)

Women Find Healthy Hormone Balance with Hemp
( ad/ article - no date)
Ganja in Jamaica: Appendix V
(book 1976) (abst 1976)
http://www.cifas.us/cannabis/PDFs/OCRGanjainJamaica.pdf
Marihuana Use. Biologic and Behavioral Aspects.

Gynecomastia and cannabis smoking: A nonassociation among US Army soldiers (abst - 1977) http://www.ncbi.nlm.nih.gov/pubmed/920892 Effects of chronic marihuana use on integrated plasma testosterone and luteinizing hormone levels. (abst - 1978)
369
Delta9-tetrahydrocannabinol increase plasma testosterone concentrations in mice (abst - 1981)

http://www.sciencemag.org/cgi/content/abstract/213/4507/581?maxtoshow=&hits=80&RESULTFORMAT =&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1600&resourcetype=HWCIT
Marijuana: interaction with the estrogen receptor

http://jpet.aspetjournals.org/cgi/content/abstract/224/2/404
(abst - 1983) (full - 1984)
Marijuana Effects on the Endocrine and Reproductive Systems

http://archives.drugabuse.gov/pdf/monographs/44.pdf
Acute Effects of Natural and Synthetic Cannabis Compounds on Prolactin Levels in Human Males. (abst 1984) http://www.ncbi.nlm.nih.gov/pubmed/6320226 Acute effects of marihuana smoking on prolactin levels in human females. (abst - 1985)
Acute effects of marihuana on luteinizing hormone in menopausal women. (abst 1985) http://www.ncbi.nlm.nih.gov/pubmed/3001780 Marijuana use does not spuriously elevate serum human chorionic gonadotropin levels. (abst 1985) http://www.ncbi.nlm.nih.gov/pubmed/2990078 Effects of Tetrahydrocannabinol on Melatonin Secretion in Man. (full + article 1986)
http://members.iowatelecom.net/sharkhaus/marijuana_melatonin.html
Marihuana use across the menstrual cycle. (abst 1986)

Effects of chronic marijuana use on testosterone, luteinizing hormone, follicle stimulating hormone, prolactin and cortisol in men and women. (abst - 1991)
THREE THINGS MARIJUANA DOESN'T DO #3

http://www.lycaeum.org/paranoia/marijuana/facts/3-mj-myths
(news - 1992)
Sex steroid influence on cannabinoid CB(1) receptor mRNA and endocannabinoid levels in the anterior pituitary gland. (abst 2000) http://www.ncbi.nlm.nih.gov/pubmed/10733937
370
Normal Human Pituitary Gland and Pituitary Adenomas Express Cannabinoid Receptor Type 1 and Synthesize Endogenous Cannabinoids: First Evidence for a Direct Role of Cannabinoids on Hormone Modulation at the Human Pituitary Level (full - 2001)
http://jcem.endojournals.org/cgi/content/full/86/6/2687?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=marihuana&searchid=1&FIRSTINDEX=1760&resourcetype=HWCIT
How might cannabinoids influence sexual behavior?
(full - 2001)
http://www.pnas.org/content/98/3/793.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabi noid&searchid=1&FIRSTINDEX=880&resourcetype=HWCIT
Dysregulated Cannabinoid Signaling Disrupts Uterine Receptivity for Embryo Implantation (full - 2001)
http://www.jbc.org/content/276/23/20523.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cann abinoid+estrogen&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
Cannabinoid effects on anxiety-related behaviours and hypothalamic neurotransmitters. (abst - 2001) http://www.ncbi.nlm.nih.gov/pubmed/11566149 The Central Cannabinoid Receptor Inactivation Suppresses Endocrine Reproductive Functions. (abst 2001)
Sex Differences in Antinociceptive and Motoric Effects of Cannabinoids.
(abst - 2001)
http://medical-journals.healia.com/doc/11698061/Sex-differences-in-antinociceptive-and-motoric-effectsof-cannabinoids
Endocrine Effects of Marijuana
(full - 2002)
http://www.docstoc.com/docs/21012384/Endocrine-Effects-of-Marijuana
Regulation of Gonadotropin-Releasing Hormone Secretion by Cannabinoids (full - 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1237039/?tool=pmcentrez Jekyll and Hyde: Two Faces of Cannabinoid Signaling in Male and Female Fertility (full - 2006)
http://edrv.endojournals.org/cgi/content/full/27/5/427?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabis&searchid=1&FIRSTINDEX=1120&resourcetype=HWCIT
The emerging role of the endocannabinoid system in endocrine regulation and energy balance. (full - 2006) http://edrv.endojournals.org/cgi/content/full/27/1/73 Cannabinoids attenuate norepinephrine-induced melatonin biosynthesis in the rat pineal gland by reducing arylalkylamine N-acetyltransferase activity without involvement of cannabinoid receptors. (full 2006)
371
Cannabis reward: biased towards the fairer sex?

(full - 2007)
Cannabinoid self-administration in rats: sex differences and the influence of ovarian function (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190022/ The rat pineal gland comprises an endocannabinoid system.
(abst 2008)
Localisation and Function of the Endocannabinoid System in the Human Ovary (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640464/?tool=pmcentrez Male-female differences in the effects of cannabinoids on sexual behavior and gonadal hormone function. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19733173 Cannabinoids and Reproduction: A Lasting and Intriguing History
(full 2010) (full - 2010)

Scientific Opinion on the safety of hemp (Cannabis genus) for use as animal feed (full 2011) (deceptive title)
http://www.hanf-info.ch/info/en/IMG/pdf/EIHA-11-05-31_EIHA-Statement_on_THC_in_feed.pdf
Drug- and cue-induced reinstatement of cannabinoid-seeking behaviour in male and female rats: influence of ovarian hormones. (abst - 2010)
Interaction of endocannabinoid system and steroid hormones in the control of colon cancer cell growth. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21412772 Gender-dependent increases with healthy aging of the human cerebral cannabinoid-type 1 receptor binding using [(18)F]MK-9470 PET. (abst 2011)
CB1 cannabinoid receptor mediates glucocorticoid effects on hormone secretion induced by volume and osmotic changes. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22211674
372
My Green Valentine: Sex and marijuana
(news/interview 2011)
HPV/ HUMAN PAPILLOMA VIRUS Marijuana use and cervical HPV/neoplasia

http://www.infectagentscancer.com/content/4/S2/P15
(abst - 2008) (full - 2009)
Bogarting that joint might decrease oral hpv among cannabis users.
Cannabinoids and Viral Infections (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903762/?tool=pmcentrez Marijuana Use is Not Associated with Cervical Human Papillomavirus Natural History or Cervical Neoplasia in HIV-Seropositive or HIV-Seronegative Women (abst - 2010)
http://cebp.aacrjournals.org/content/19/3/869.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabinoid&searchid=1&FIRSTINDEX=2960&resourcetype=HWCIT
HU-210- synthetic, CB 1 & CB 2 agonist Learning impairment produced in rats by the cannabinoid agonist HU 210 in a watermaze task. (abst 1999) http://www.ncbi.nlm.nih.gov/pubmed/10548271 Suppression of Nerve Growth Factor Trk Receptors and Prolactin Receptors by Endocannabinoids Leads to Inhibition of Human Breast and Prostate Cancer Cell Proliferation (full - 2000) http://endo.endojournals.org/cgi/content/full/141/1/118 Effects of cannabinoid receptor agonists on neuronally-evoked contractions of urinary bladder tissues isolated from rat, mouse, pig, dog, monkey and human (full - 2000)
Inhibitory effects of the cannabinoid agonist HU 210 on rat sexual behaviour. (abst 2000) http://www.ncbi.nlm.nih.gov/pubmed/10913795
373
Increase of the heart arrhythmogenic resistance and decrease of the myocardial necrosis zone during activation of cannabinoid receptors (abst 2002)
The cannabinoids R(-)-7-hydroxy-delta-6-tetra-hydrocannabinol-dimethylheptyl (HU210), 2-O-arachidonoylglycerylether (HU-310) and arachidonyl-2-chloroethylamide (ACEA) increase isoflurane provoked sleep duration by activation of cannabinoids 1 (CB1)-receptors in mice. (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/12095655 Inhibition of tumor angiogenesis by cannabinoids (full - 2003)
CB1 cannabinoid receptor antagonism promotes remodeling and cannabinoid treatment prevents endothelial dysfunction and hypotension in rats with myocardial infarction (full - 2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573770/?tool=pmcentrez Drug-induced hypothermia reduces ischemic damage: effects of the cannabinoid HU-210. (full - 2003) http://stroke.ahajournals.org/cgi/reprint/34/8/2000 Histamine induced responses are attenuated by a cannabinoid receptor agonist in human skin. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12835895 The endogenous cannabinoid system protects against colonic inflammation
(full - 2004)
Direct cerebrovascular effects of CB1 receptor activation by the synthetic endocannabinoid HU-210 in vivo (full - 2005)
http://www.nature.com/jcbfm/journal/v25/n1s/full/9591524.0581a.html
374
Is cannabis good for your brain?
(news - 2005) (news - 2005) (news - 2005)
http://arstechnica.com/science/news/2005/10/1529.ars
Marijuana May Spur New Brain Cells
Study Shows Marijuana Promotes Neuron Growth Marijuana May Grow Neurons in the Brain Surprising Brain Effects From Pot-Like Drug
http://english.ohmynews.com/articleview/article_view.asp?menu=c10400&no=253377&rel_no=1
(news - 2005) (news 2005) (news 2005)
http://www.webmd.com/mental-health/news/20051013/surprising-brain-effects-from-pot-like-drug

Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751298/?tool=pmcentrez Arthritis and cannabinoids: HU-210 and Win-55,212-2 prevent IL-1alpha-induced matrix degradation in bovine articular chondrocytes in-vitro. (abst - 2006)
Cannabinoids Ameliorate Pain and Reduce Disease Pathology in Cerulein-Induced Acute Pancreatitis (full - 2007) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2268094 Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon (full - 2007)
Cannabinoids Induce Glioma Stem-like Cell Differentiation and Inhibit Gliomagenesis (full - 2007) http://www.jbc.org/content/282/9/6854.long The synthetic cannabinoid HU210 induces spatial memory deficits and suppresses hippocampal firing rate in rats (full 2007)
The synthetic cannabinoid HU-210 attenuates neural damage in diabetic mice and hyperglycemic pheochromocytoma PC12 cells (abst - 2007)
375
Excitotoxicity in a chronic model of multiple sclerosis: Neuroprotective effects of cannabinoids through CB1 and CB2 receptor activation. (abst 2007)
Repeated Cannabinoid Injections into the Rat Periaqueductal Gray Enhances Subsequent Morphine Antinociception (full - 2008)
Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma (full - 2009) http://mct.aacrjournals.org/content/8/7/1838.full Spice drugs: cannabinoids as a new designer drugs. (abst - 2009)
Involvement of cannabinoid-1 and cannabinoid-2 receptors in septic ileus.

(full 2010)
(abst - 2010)
The potential for clinical use of cannabinoids in treatment of cardiovascular diseases. (full 2011) http://onlinelibrary.wiley.com/doi/10.1111/j.1755-5922.2010.00233.x/pdf Beyond THC: The New Generation of Cannabinoid Designer Drugs.
(full 2011)
Investigating a not-so-natural high.

http://pubs.acs.org/doi/full/10.1021/ac900564u
(full 2011)
Pharmacological activation/inhibition of the cannabinoid system affects alcohol withdrawal-induced neuronal hypersensitivity to excitotoxic insults. (abst 2011)
(abst 2011)
The effects of cannabinoid drugs on abnormal involuntary movements in dyskinetic and non-dyskinetic 6-hydroxydopamine lesioned rats. (abst 2011)
376
Increased brain metabolism after acute administration of the synthetic cannabinoid HU210: A small animal PET imaging study with (18)F-FDG. (abst 2011)
HU-211 / DEXANABINOL - synthetic, CB 2 agonist A nonpsychotropic cannabinoid, HU-211, has cerebroprotective effects after closed head injury in the rat. (abst 1993) http://www.ncbi.nlm.nih.gov/pubmed/8411215 HU-211, a Novel Noncompetitive N-Methyl-D-Aspartate Antagonist, Improves Neurological Deficit and Reduces Infarct Volume After Reversible Focal Cerebral Ischemia in the Rat (full - 1995) http://stroke.ahajournals.org/cgi/content/full/26/12/2313 45Ca accumulation in rat brain after closed head injury; attenuation by the novel neuroprotective agent HU-211. (abst 1995) http://www.ncbi.nlm.nih.gov/pubmed/7583233 Development of HU-211 as a neuroprotectant for ischemic brain damage.
(abst 1995)
A novel nonpsychotropic cannabinoid, HU-211, in the treatment of experimental pneumococcal meningitis. (full - 1996) http://jid.oxfordjournals.org/content/173/3/735.long HU-211, a nonpsychotropic cannabinoid, produces short- and long-term neuroprotection after optic nerve axotomy. (abst 1996) http://www.ncbi.nlm.nih.gov/pubmed/8714863 Cytokine production in the brain following closed head injury: dexanabinol (HU-211) is a novel TNF-alpha inhibitor and an effective neuroprotectant. (abst 1997)
Protection Against Septic Shock and Suppression of Tumor Necrosis Factor and Nitric Oxide Production by Dexanabinol (HU-211), a Nonpsychotropic Cannabinoid (full - 1997) http://jpet.aspetjournals.org/content/283/2/918.full Dexanabinol; a novel neuroprotective drug in experimental focal cerebral ischemia. (abst 1999) http://www.ncbi.nlm.nih.gov/pubmed/10202976 Cannabinoids in clinical practice. (abst - 2000)
Dexanabinol (HU-211) in the treatment of severe closed head injury: a randomized, placebo-controlled, phase II clinical trial. (abst - 2002)
377
Dexanabinol: a novel cannabinoid with neuroprotective properties.

(abst 2003)
Dexanabinol (HU-211) has a beneficial effect on axonal sprouting and survival after rat optic nerve crush injury. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12535983 Therapeutic potential of cannabinoids in CNS disease.
(abst - 2003)
Dexanabinol: dexanabinone, HU 211, PA 50211, PRS 211007, sinnabidol. (abst - 2003) http://www.ncbi.nlm.nih.gov/pubmed/12757406 Dexanabinol prevents development of vasospasm in the rat femoral artery model. (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/18256864 Latest Studies Imply That Cannabinoids Are Protective Against Alcohol-Induced Brain Damage (news 2011) http://networkedblogs.com/mFuuX
HU-308 - synthetic, CB2 agonist HU-308: a specific agonist for CB(2), a peripheral cannabinoid receptor.
(full - 1999)
Peripheral cannabinoid receptor, CB2, regulates bone mass

(full - 2005)
Cannabinoid CB2 receptor agonist activity in the hindpaw incision model of postoperative pain. (abst - 2005) http://www.ncbi.nlm.nih.gov/pubmed/16316653 Activation of CB2 receptor attenuates bone loss in osteoporosis (news - 2006)
Non-psychoactive CB2 cannabinoid agonists stimulate neural progenitor proliferation (full 2006) http://www.fasebj.org/content/20/13/2405.long Cannabinoid-2 receptor agonist HU-308 protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and apoptosis (full - 2007) http://www.jleukbio.org/cgi/content/full/82/6/1382
378
HU-310 The cannabinoids R(-)-7-hydroxy-delta-6-tetra-hydrocannabinol-dimethylheptyl (HU210), 2-O-arachidonoylglycerylether (HU-310) and arachidonyl-2-chloroethylamide (ACEA) increase isoflurane provoked sleep duration by activation of cannabinoids 1 (CB1)-receptors in mice. (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/12095655
HU-320 - synthetic A novel synthetic, nonpsychoactive cannabinoid acid (HU-320) with antiinflammatory properties in murine collagen-induced arthritis. (full- 2004)
HU-239- see Ajulemic Acid
HU-331 - synthetic A cannabinoid quinone inhibits angiogenesis by targeting vascular endothelial cells. (full - 2006) http://molpharm.aspetjournals.org/content/70/1/51.long A Cannabinoid Anticancer Quinone, HU-331, Is More Potent and Less Cardiotoxic Than Doxorubicin: A Comparative in Vivo Study (full - 2007)
379
HU-331, a novel cannabinoid-based anticancer topoisomerase II inhibitor

http://mct.aacrjournals.org/content/6/1/173.long
(full - 2007)
HU-331: a cannabinoid quinone, with uncommon cytotoxic properties and low toxicity. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17714026
HU-910 synthetic, CB2 agonist A new cannabinoid 2 receptor agonist HU-910 attenuates oxidative stress, inflammation, and cell death associated with hepatic ischemia/reperfusion injury. (abst 2011)
HUNTINGTON'S DISEASE Tetrahydrocannabinol potentiates reserpine-induced hypokinesia.

(abst 1981) (abst - 1986)
EFFECTS OF CANNABIDIOL IN HUNTINGTON'S DISEASE

http://www.druglibrary.org/schaffer/hemp/medical/hunting1.htm
Loss of cannabinoid receptors in the substantia nigra in Huntington's disease. (abst 1993) http://www.ncbi.nlm.nih.gov/pubmed/8255419 Cannabis in movement disorders. (abst - 1999)
Changes in endocannabinoid transmission in the basal ganglia in a rat model of Huntington's disease. (abst 2001) http://www.ncbi.nlm.nih.gov/pubmed/11447320 Alleviation of motor hyperactivity and neurochemical deficits by endocannabinoid uptake inhibition in a rat model of Huntington's disease. (abst 2002)
380
Loss of cannabinoid CB(1) receptors in the basal ganglia in the late akinetic phase of rats with experimental Huntington's disease. (abst 2002)
Compounds acting at the endocannabinoid and/or endovanilloid systems reduce hyperkinesia in a rat model of Huntington's disease. (abst 2003)
Effects of cannabinoids in the rat model of Huntington's disease generated by an intrastriatal injection of malonate. (abst 2003)
The endocannabinoid system and Huntington's disease.

(abst 2003)
Structure, expression and regulation of the cannabinoid receptor gene (CB1) in Huntington's disease transgenic mice. (full 2004)
Delayed onset of Huntington's disease in mice in an enriched environment correlates with delayed loss of cannabinoid CB1 receptors. (abst 2004)
Cannabinoid control of motor function at the basal ganglia.

(abst 2005)
Abnormal sensitivity to cannabinoid receptor stimulation might contribute to altered gamma-aminobutyric acid transmission in the striatum of R6/2 Huntington's disease mice. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/15953496 Nabilone Could Treat Chorea and Irritability in Huntingtons Disease
http://neuro.psychiatryonline.org/cgi/content/short/18/4/553?rss=1
(letter - 2006)

(abst - 2007) (full - 2008)
Altered Lipid Metabolism in Brain Injury and Disorders

The endocannabinoid system in Huntington's disease.

(abst - 2008)
381
The endocannabinoid pathway in Huntington's disease: a comparison with other neurodegenerative diseases. (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/17276576 Role of CB2 receptors in neuroprotective effects of cannabinoids.
(abst - 2008)
Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity (full - 2009) http://brain.oxfordjournals.org/content/132/11/3152.long Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease. (abst 2009)
A pilot study using nabilone for symptomatic treatment in Huntington's disease. (abst 2009)
http://www.unboundmedicine.com/medline/ebm/record/19845035/abstract/A_pilot_study_using_nabilone_ for_symptomatic_treatment_in_Huntington%27s_disease_

(abst - 2009)
Cannabinoid CB2 receptor agonists protect the striatum against malonate toxicity: relevance for Huntington's disease. (abst - 2009)
Widespread Decrease of Type 1 Cannabinoid Receptor Availability in Huntington Disease In Vivo (full 2010) http://jnm.snmjournals.org/cgi/content/full/51/9/1413 Cannabinoids and Dementia: A Review of Clinical and Preclinical Data
(full 2010)
Neuroprotective potential of CB1 receptor agonists in an in vitro model of Huntington's disease. (full 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931573/?tool=pubmed The endocannabinoid system in gp120-mediated insults and HIV-associated dementia. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20353779 Behavioural and molecular consequences of chronic cannabinoid treatment in Huntington's disease transgenic mice. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20600638/abstract/Behavioural_and_molecular_co nsequences_of_chronic_cannabinoid_treatment_in_Huntington%27s_disease_transgenic_mice_
382
Neuroprotective effects of phytocannabinoid-based medicines in experimental models of Huntington's disease. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21674569 Prospects for cannabinoid therapies in basal ganglia disorders.
(abst 2011)
Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/20929960 Worsening of Huntington disease phenotype in CB1 receptor knockout mice. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21406230/abstract/Worsening_of_Huntington_dise ase_phenotype_in_CB1_receptor_knockout_mice_
Metabolic and Type 1 cannabinoid receptor imaging of a transgenic rat model in the early phase of Huntington disease (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21459091/abstract/Metabolic_and_Type_1_cannab inoid_receptor_imaging_of_a_transgenic_rat_model_in_the_early_phase_of_Huntington_disease_
HYPEREMESIS see CANNABINOID HYPEREMESIS SYNDROME
HYSTERECTOMY Effect of nabilone on nausea and vomiting after total abdominal hysterectomy (abst - 1994) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=137
IBS - see BOWEL DISORDERS
383
IDIOPATHIC INTRACRANIAL HYPERTENSION Dronabinol reduces signs and symptoms of idiopathic intracranial hypertension : a case report (abst + 1st page - 2006) http://www.liebertonline.com/doi/abs/10.1089/jop.2006.22.68 Science: Cannabis and THC effective in the treatment of idiopathic intracranial hypertension (news - 2006)
IDRASIL a natural THC pill New Cannabis Pill On Track For 2012 Debut A legit cannabis pill?!? You dont say! (news 2011)
http://www.theweedblog.com/new-cannabis-pill-on-track-for-2012-debut/
(news 2011)
http://hailmaryjane.com/a-legit-cannabis-pill-you-dont-say/
IMMUNE SYSTEM Presence and functional regulation of cannabinoid receptors in immune cells. (abst 1999)
Cannabinoids, immune system and cytokine network.

(abst 2000)
Immunomodulation by Cannabinoids is Absent in Mice Deficient for the Cannabinoid Cb(2) Receptor. (abst 2000)
Activation of PAF receptors results in enhanced synthesis of 2-arachidonoylglycerol (2AG) in immune cells (full - 2002)
Endocannabinoids in the immune system and cancer.

(abst - 2002) (full 2003)
The cannabinoid system and immune modulation

http://www.jleukbio.org/content/74/4/486.full.pdf+html
384
Cannabis May Suppress Immune System
(news - 2003) (abst 2004)
Cannabinoids and the immune system. Of men, mice and cells

Cannabinoid receptors in microglia of the central nervous system: immune functional relevance. (full - 2005) http://www.jleukbio.org/content/78/6/1192.long CB2 cannabinoid receptor agonist, JWH-015 triggers apoptosis in immune cells: Potential role for CB2 selective ligands as immunosuppressive agents (full 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1864948 / CB2 receptors in the brain: role in central immune function
(full - 2007)
Anandamide and Delta9-tetrahydrocannabinol directly inhibit cells of the immune system via CB2 receptors. (full - 2007)
Targeting astrocytomas and invading immune cells with cannabinoids: a promising therapeutic avenue. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17952648 Crucial Role of CB2 Cannabinoid Receptor in the Regulation of Central Immune Responses during Neuropathic Pain (full - 2008)
Immunomodulatory lipids in plants: plant fatty acid amides and the human endocannabinoid system. (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/18275004 Initial study of Hemp seeds protein on antifatigue and the immunomodulation effects in mice (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/18589601 Initial study of Hemp seeds protein on antifatigue and the immunomodulation effects in mice (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/18589601 Emerging Role of the CB2 Cannabinoid Receptor in Immune Regulation and Therapeutic Prospects (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768535/?tool=pmcentrez Cannabinoids as novel anti-inflammatory drugs. (full - 2009) (full 2009)
Cannabidiol-induced lymphopenia does not involve NKT and NK cells.

http://www.jpp.krakow.pl/journal/archive/10_09_s3/pdf/99_10_09_s3_article.pdf
385
The morphology of the immune system in opiomania, cannabism, and polynarcotism (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19938701/full_citation/%5BThe_morphology_of_t he_immune_system_in_opiomania_cannabism_and_polynarcotism%5D
Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression. (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005548/?tool=pubmed Do cannabinoids have a therapeutic role in transplantation
(full 2010)
Cannabinoid receptor activation leads to massive mobilization of myeloid-derived suppressor cells with potent immunosuppressive properties (full 2010)
http://onlinelibrary.wiley.com/doi/10.1002/eji.201040667/full
Cannabinoids and Viral Infections
(full - 2010)
Cannabidiol attenuates delayed-type hypersensitivity reactions via suppressing T-cell and macrophage reactivity. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/21042286 Role of Myeloid-Derived Suppressor Cells in Amelioration of Experimental Autoimmune Hepatitis Following Activation of TRPV1 Receptors by Cannabidiol (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069975/?tool=pmcentrez New blood brothers: the GPR55 and CB2 partnership
(full 2011)
Immunomodulatory properties of kappa opioids and synthetic cannabinoids in HIV-1 neuropathogenesis. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21850403 Cannabis use and Cognitive Function: Eight Year Trajectory in a Young Adult Cohort. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21749524 Commentary: Functional Neuronal CB2 Cannabinoid Receptors in the CNS. (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137183/?tool=pubmed Cannabinoids and Innate Immunity: Taking a Toll on Neuroinflammation (abst- with link to full 2011) http://www.tswj.com/2011/230786/abs/ Deletion of cannabinoid receptors 1 and 2 exacerbates APC function to increase inflammation and cellular immunity during influenza infection. (abst 2011)
Design and evaluation of a novel fluorescent CB2 ligand as probe for receptor visualization in immune cells. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21855337
386
INCONTINENCE - see BLADDER OVERACTIVITY
INDICATIONS AND CLINICAL USES HEMP AS A MEDICAMENT : Survey of clinical experiences

(full - 1955)
Cannabis as a Medicine?
(editorial - 1995)
http://bja.oxfordjournals.org/cgi/reprint/74/4/359?maxtoshow=&hits=80&RESULTFORMAT=1&andorex acttitle=and&andorexacttitleabs=and&fulltext=cannabinoid&andorexactfulltext=and&searchid=1&FIRSTI NDEX=0&sortspec=relevance&resourcetype=HWCIT
Medicinal Applications of Delta-9-Tetrahydrocannabinol and Marijuana
(full - 1997)
http://www.annals.org/content/126/10/791.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=can nabis&searchid=1&FIRSTINDEX=1200&resourcetype=HWCIT
Hemp and Health
(book - 1999) http://www.rexresearch.com/hhusb/hmphlth.htm#hhl2s (full - 2001)

Cannabis and cannabinoids: pharmacology, toxicology, and therapeutic potential Chapter 11 Review of Therapeutic Effects (book excerpt - 2002)
http://books.google.com/books?id=JvIyVk2IL_sC&pg=PA123#v=onepage&q&f=false

( abst - 2003) (full - 2004)
"Dr. Tod's List" - Chronic Conditions Treated With Cannabis

(The inspiration for this List!) http://www.letfreedomgrow.com/cmu/DrTodHMikuriya_list.htm
Potential Merits of Cannabinoids for Medical Uses

http://www.fda.gov/NewsEvents/Testimony/ucm114741.htm
(testimony - 2004)
Marijuana-Like Compounds May Aid Array Of Debiliatiing Conditions Ranging From Parkinson's Disease To Pain (news - 2004)
Survey of Australians using cannabis for medical purposes

(full - 2005)
Pharmacological actions and therapeutic uses of cannabis and cannabinoids (full 2008) http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2044.2001.02269.x/full
387
4.0 Purported Indications and Clinical Use
(abst - 2009) (news - 2010)
http://www.hc-sc.gc.ca/dhp-mps/marihuana/how-comment/medpract/infoprof/indications-eng.php
Cannabis Rx: Cutting Through the Misinformation : Dr. Andrew Weil
Who Are Medical Marijuana Patients? Population Characteristics from Nine California Assessment Clinics. (abst + news 2010)
http://blog.norml.org/2011/07/21/who-are-americas-medical-marijuana-patients/
Cannabis and Its Derivatives: Review of Medical Use

http://www.jabfm.org/cgi/content/full/24/4/452
(full 2011)
INFLUENZA- see FLU
INJURIES - see WOUNDS AND INJURIES
INTERACTIONS WITH OTHER DRUGS INTERACTIONS OF 1-TETRAHYDROCANNABINOL WITH BARBITURATES AND METHAMPHETAMINE (abst - 1970)
Effect of cannabis and certain of its constituents on pentobarbitone sleeping time and phenazone metabolism (full - 1972) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1666020/ Proceedings: Effects of chronic and acute cannabis treatment upon thiopentone anaesthesia in rabbits. (full - 1972)
Cardiovascular and respiratory effects of cannabis extracts and 1-tetra-hydrocannabinol ( 1-THC). (abst - 1973)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1776288/pdf/brjpharm00549-0201a.pdf
Interaction of cannabis and general anaesthetic agents in mice

(full - 1974)
388
Combination of delta9-tetrahydrocannabinol with oxymorphone or pentobarbital: Effects on ventilatory control and cardiovascular dynamics. (click for PDF- full - 1975)
Interactions in man of delta-9-tetrahydrocannabinol. II. Cannabinol and cannabidiol. (abst 1975) http://www.ncbi.nlm.nih.gov/pubmed/1097148 The analgesic properties of delta-9-tetrahydrocannabinol and codeine.
(abst - 1975)
Effects of marihuana combined with secobarbital.

(abst 1975)
The Effects of Delta-9-Tetrahydrocannabinol (Cannabis) on Cardiac Performance with and without Beta Blockade (full - 1976)
http://circ.ahajournals.org/cgi/reprint/53/4/703?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=mar ihuana&searchid=1&FIRSTINDEX=2080&resourcetype=HWCIT
Effects of marihuana-dextroamphetamine combination.

(abst 1976)
Cannabidiol--antiepileptic drug comparisons and interactions in experimentally induced seizures in rats. (full - 1977)
The effect of delta 9-tetrahydrocannabinol, cannabidiol, and cannabinol on the anaesthesia induced by various anaesthetic agents in mice. (abst - 1977)
Propranolol Effects on Acute Marihuana Intoxication in Man.

(abst 1977)
Enhanced Biotransformation of Theophylline in Marihuana and Tobacco Smokers. (abst 1978) http://www.ncbi.nlm.nih.gov/pubmed/688731 Effects of drugs on behavior in pigeons tolerant to delta 9-tetrahydrocannabinol. (abst - 1980)
http://jpet.aspetjournals.org/content/212/1/85.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabis&searchid=1&FIRSTINDEX=3760&resourcetype=HWCIT.
Tetrahydrocannabinol potentiates reserpine-induced hypokinesia.

(abst 1981) (abst 1983)
Adverse Interaction Between Disulfiram and Marijuana: a Case Report.
http://medical-journals.healia.com/doc/6295192/Adverse-interaction-between-disulfiram-and-marijuana-acase-report
389
ANALGESIC INTERACTION BETWEEN NITROUS OXIDE AND DELTA-9TETRAHYDEROCANNABINOL IN THE RAT (abst - 1983)
http://bja.oxfordjournals.org/cgi/content/abstract/55/10/997?maxtoshow=&hits=80&RESULTFORMAT=1 &andorexacttitle=and&andorexacttitleabs=and&fulltext=cannabinoid&andorexactfulltext=and&searchid=1 &FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT
Respiratory effects of cocaine "freebasing" among habitual users of marijuana with or without tobacco. (abst - 1987)
http://chestjournal.chestpubs.org/content/92/4/638.abstract?maxtoshow=&hits=80&RESULTFORMAT=& fulltext=marihuana&searchid=1&FIRSTINDEX=1920&resourcetype=HWCIT
Flashback Following Use of Cannabis--a Review
(abst 1991)
http://medical-journals.healia.com/doc/1761271/Flashback-following-use-of-cannabis-a-review
Marihuana attenuates the rise in plasma ethanol levels in human subjects. (abst 1992) http://www.ncbi.nlm.nih.gov/pubmed/1326277 Marihuana smoking increases plasma cocaine levels and subjective reports of euphoria in male volunteers. (abst 1994) http://www.ncbi.nlm.nih.gov/pubmed/7938127 Anandamide and delta 9-THC dilation of cerebral arterioles is blocked by indomethacin (abst - 1995)
Marijuana and chocolate.
(abst - 1996)
Case report: adverse effects of taking tricyclic antidepressants and smoking marijuana. (full - 1999) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2328650/?tool=pmcentrez&page=1 Involvement of central and peripheral cannabinoid receptors in the regulation of heart resistance to arrhythmogenic effects of epinephrine. (abst - 2000)
Protective effects of cannabinoid receptor ligands analogous to anandamide against cocaine toxicity. (abst 2001) http://www.ncbi.nlm.nih.gov/pubmed/11828716 Decrease in efficacy and potency of nonsteroidal anti-inflammatory drugs by chronic delta(9)-tetrahydrocannabinol administration. (full 2002)
390
Tobacco and Cannabis Smoking Cessation Can Lead to Intoxication with Clozapine or Olanzapine. (abst 2002)
http://medical-journals.healia.com/doc/11981356/Tobacco-and-cannabis-smoking-cessation-can-lead-tointoxication-with-clozapine-or-olanzapine
Haloperidol, but not clozapine, produces dramatic catalepsy in delta9-THC-treated rats: possible clinical implications. (full - 2003)
Cannabis reduces opioid dose in the treatment of chronic non-cancer pain. (full - 2003) http://www.jpsmjournal.com/article/S0885-3924(03)00142-8/fulltext Manipulation of the endocannabinoid system by a general anaesthetic.
(full 2003)
Modulation of oral morphine antinociceptive tolerance and naloxone-precipitated withdrawal signs by oral Delta 9-tetrahydrocannabinol. (full 2003)
Topical cannabinoid enhances topical morphine antinociception.

(abst - 2003)
Cannabinoids prevent the acute hyperthermia and partially protect against the 5-HT depleting effects of MDMA ("Ecstasy") in rats. (abst - 2004)
Enhancement of transdermal fentanyl and buprenorphine antinociception by transdermal delta9-tetrahydrocannabinol. (abst - 2005) http://www.ncbi.nlm.nih.gov/pubmed/16288738 Influence of medicinal cannabis (MC) on the pharmacokinetics (PK) of docetaxel (DOC) and irinotecan (CPT-11) (abst - 2005)
http://www.aacrmeetingabstracts.org/cgi/content/abstract/2005/1/938c?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1840 &resourcetype=HWCIT
Modulation of paraoxon toxicity by the cannabinoid receptor agonist WIN 55,212-2. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16956707 Local interactions between anandamide, an endocannabinoid, and ibuprofen, a nonsteroidal anti-inflammatory drug, in acute and inflammatory pain (abst - 2006)
Benefits of an add-on treatment with the synthetic cannabinomimetic nabilone on patients with chronic pain - a randomized controlled trial. (abst - 2006)
391
Synergistic affective analgesic interaction between delta-9-tetrahydrocannabinol and morphine. (abst - 2006)
Arachidonyl-2'-chloroethylamide, a highly selective cannabinoid CB1 receptor agonist, enhances the anticonvulsant action of valproate in the mouse maximal electroshockinduced seizure model. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16930590 Cannabinoids Enhance Analgesic Effects Of Anti-Inflammatory Drugs, Study Says (news - 2006) http://www.norml.org/index.cfm?Group_ID=6819 Opioid Antagonism of Cannabinoid Effects: Differences between Marijuana Smokers and Nonmarijuana Smokers (full - 2007)
http://www.nature.com/npp/journal/v32/n6/abs/1301243a.html
Low dose combination of morphine and 9-tetrahydrocannabinol circumvents antinociceptive tolerance and apparent desensitization of receptors (full - 2007)
Medicinal cannabis does not influence the clinical pharmacokinetics of irinotecan and docetaxel. (full - 2007) http://theoncologist.alphamedpress.org/cgi/content/full/12/3/291 Antinociceptive Synergy Between the Cannabinoid Receptor Agonist WIN 55,212-2 and Bupivacaine in the Rat Formalin Test (full - 2007)
The multidrug transporter ABCG2 (BCRP) is inhibited by plant-derived cannabinoids. (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190019/?tool=pubmed Activation of cannabinoid CB1 and CB2 receptors suppresses neuropathic nociception evoked by the chemotherapeutic agent vincristine in rats. (full 2007)
Propranolol effects on acute marihuana intoxication in man

http://www.springerlink.com/content/k101520212421877/
(abst 2007)
Efficacy of dronabinol alone and in combination with ondansetron versus ondansetron alone for delayed chemotherapy-induced nausea and vomiting. (abst - 2007)
392
Science: The use of cannabis does not influence the efficacy of two anti-cancer drugs, a clinical study finds (news - 2007)
Priapism, ecstasy, and marijuana: is there a connection?

(full - 2008) (full - 2008)
Propofol Sedation Is Reduced by {Delta}9-Tetrahydrocannabinol in Mice
Interaction of plant cannabinoids with the multidrug transporter ABCC1 (MRP1). (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18619955 Enhancing the in vitro cytotoxic activity of 9-tetrahydrocannabinol in leukemic cells through a combinatorial approach (abst - 2008)
http://www.informaworld.com/smpp/content~content=a794665906?words=cannabis&hash=843258562
Effects of Cannabinoids on Caffeine Contractures in Slow and Fast Skeletal Muscle Fibers of the Frog (full - 2009)
Cannabinoid receptor-independent cytotoxic effects of cannabinoids in human colorectal carcinoma cells: synergism with 5-fluorouracil. (abst + 1st page 2009)
http://www.springerlink.com/content/45008p9643k139l4/
Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines. (abst 2009) http://www.ncbi.nlm.nih.gov/pubmed/19394652 Cannabis Coadministration Potentiates the Effects of "Ecstasy" on Heart Rate and Temperature in Humans. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19440186/abstract/Cannabis_Coadministration_Po tentiates_the_Effects_of_%22Ecstasy%22_on_Heart_Rate_and_Temperature_in_Humans_
Induction dose of propofol in patients using cannabis.
(abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19237981/abstract/Induction_dose_of_propofol_in _patients_using_cannabis_
393
Cannabinoids, Opioids and MDMA: Neuropsychological Interactions Related to Addiction. (abst - 2009)
Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania (abst 2009)
http://jop.sagepub.com/content/25/2/274.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=c annabinoid&searchid=1&FIRSTINDEX=320&sortspec=date&resourcetype=HWCIT
An unusual cause of syncope
(abst - 2009)
http://casereports.bmj.com/content/2009/bcr.09.2009.2282.abstract?maxtoshow=&hits=80&RESULTFOR MAT=&fulltext=cannabis&searchid=1&FIRSTINDEX=320&sortspec=date&resourcetype=HWCIT
Interaction of the cannabinoid and opioid systems in the modulation of nociception. (abst - 2009)
Smoking Pot, Cigarettes Ups COPD Risk
(news - 2009) (full - 2010)
http://www.webmd.com/news/20090413/smoking-pot-cigarettes-ups-copd-risk
THC Prevents MDMA Neurotoxicity in Mice.
Influence of ethanol on cannabinoid pharmacokinetic parameters in chronic users (full - 2010) http://www.springerlink.com/content/511171841x1u1521/fulltext.html The safety of modafinil in combination with oral 9-tetrahydrocannabinol in humans (abst - 2010)
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T0N-51S0WM11&_user=10&_coverDate=12%2F21%2F2010&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sor t=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=a35b5a 1c810b0d18a28df6a605746310&searchtype=a
Methamphetamine neurotoxicity increases brain expression and alters behavioral functions of CB cannabinoid receptors. (abst 2010)
Probable Interaction Between Warfarin and Marijuana Smoking
(abst - 2010)
http://www.unboundmedicine.com/medline/ebm/record/19531696/abstract/Probable_Interaction_Between_ Warfarin_and_Marijuana_Smoking__July/August__
Opioid antagonism enhances marijuana's effects in heavy marijuana smokers. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20490465/abstract/Opioid_antagonism_enhances_ marijuana%27s_effects_in_heavy_marijuana_smokers_
394
Adolescent cannabis use increases risk for cocaine-induced paranoia.
(abst - 2010)
http://www.unboundmedicine.com/medline/ebm/record/19944543/full_citation/Adolescent_cannabis_use_i ncreases_risk_for_cocaine_induced_paranoia_
The analgesic potential of cannabinoids.

(abst - 2010) (news - 2010) (news 2010)
Chocolate: The Good, the Bad and the Angry
Cannabis-enhancing plant to be marketed worldwide as new drug
http://www.mnn.com/health/fitness-well-being/stories/cannabis-enhancing-plant-to-be-marketedworldwide-as-new-drug
Acute effects of MDMA (3,4-methylenedioxymethamphetamine) on EEG oscillations: alone and in combination with ethanol or THC (delta-9-tetrahydrocannabinol) (full 2011)
Combined effects of acute, very-low-dose ethanol and delta(9)-tetrahydrocannabinol in healthy human volunteers (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21110996 Inhibition of monoacylglycerol lipase (MAGL) attenuates NSAID-induced gastric hemorrhages in mice. (full 2011)
http://jpet.aspetjournals.org/content/early/2011/06/09/jpet.110.175778.long
Cannabinoid system and cyclooxygenases inhibitors
(full 2011)
Role of GLT-1 transporter activation in prevention of cannabinoid tolerance by the betalactam antibiotic, ceftriaxone, in mice. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21536061/abstract/Role_of_GLT_1_transporter_ac tivation_in_prevention_of_cannabinoid_tolerance_by_the_beta_lactam_antibiotic_ceftriaxone_in_mice_
Cannabis in Palliative Medicine: Improving Care and Reducing Opioid-Related Morbidity (abst - 2011)
http://ajh.sagepub.com/content/early/2011/04/07/1049909111402318.abstract?maxtoshow=&hits=80&RES ULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype=H WCIT
395
Cannabinoid-opioid interaction in chronic pain.
(abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/22048225/abstract/Cannabinoid_opioid_interaction _in_chronic_pain_
A combined preclinical therapy of cannabinoids and temozolomide against glioma. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21220494 The safety of modafinil in combination with oral 9-tetrahydrocannabinol in humans. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21176784 Cannabidiol potentiates (9)-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21667074 Chronic administration of THC prevents the behavioral effects of intermittent adolescent MDMA administration and attenuates MDMA-induced hyperthermia and neurotoxicity in rats (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21763331 The G protein-coupled cannabinoid-1 (CB(1)) receptor of mammalian brain: Inhibition by phthalate esters in vitro. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21763743 Combined effects of THC and caffeine on working memory in rats.
(abst 2011)
The interplay of cannabinoid and NMDA glutamate receptor systems in humans: preliminary evidence of interactive effects of cannabidiol and ketamine in healthy human subjects. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21062637/abstract/The_interplay_of_cannabinoid_ and_NMDA_glutamate_receptor_systems_in_humans:_preliminary_evidence_of_interactive_effects_of_c annabidiol_and_ketamine_in_healthy_human_subjects_
Pretreatment with 9-tetrahydrocannabinol (THC) increases cocaine-stimulated activity in adolescent but not adult male rats (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21951601/abstract/Pretreatment_with_%CE%949_ tetrahydrocannabinol__THC__increases_cocaine_stimulated_activity_in_adolescent_but_not_adult_male_ rats_
Previous exposure to delta9-tetrahydrocannibinol enhances locomotor responding to but not self-administration of amphetamine. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21389094/abstract/Previous_exposure_to_delta9_t etrahydrocannibinol_enhances_locomotor_responding_to_but_not_self_administration_of_amphetamine_
THC-methadone and THC-naltrexone interactions on discrimination, antinociception, and locomotion in rats. (abst - 2011)
http://www.unboundmedicine.com/medline/ebm/record/21716095/abstract/THC_methadone_and_THC_na ltrexone_interactions_on_discrimination_antinociception_and_locomotion_in_rats_
396
Pharmacokinetics of a combination of 9-tetrahydro-cannabinol and celecoxib in a porcine model of hemorrhagic shock. (abst 2011)
Low-volume binary drug therapy for the treatment of hypovolemia.
(abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21330941/abstract/Low_volume_binary_drug_ther apy_for_the_treatment_of_hypovolemia_
Efavirenz interference in urine screening immunoassays for tetrahydrocannabinol. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22067092 Clozapine and SCH 23390 prevent the spatial working memory disruption induced by 9-THC administration into the medial prefrontal cortex. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21281616/abstract/Clozapine_and_SCH_23390_pr event_the_spatial_working_memory_disruption_induced_by_%CE%949_THC_administration_into_the_m edial_prefrontal_cortex_
Marijuana, Narcotics Help Patients Reduce Chronic Pain, Study Finds (news 2011)
http://www.huffingtonpost.com/2011/12/08/marijuana-narcotics-help-patients-reducepain_n_1137416.html
31 - IP 751 see AJULEMIC ACID
ISAACS SYNDROME/ ACQUIRED NEUROMYOTONIA Cannabinoids affect dendritic cell (DC) potassium channel function and modulate DC T cell stimulatory capacity. (full 2008) http://www.jimmunol.org/content/181/5/3057.long Science: Dramatic improvement of neuromyotonia (Isaacs' syndrome) with THC in a case report (abst 2010)
IQ/ MEMORY/ COGNITIVE EFFECTS Marihuana and Memory: Acquisition or Retrieval? (abst - 1971)
http://www.sciencemag.org/cgi/content/abstract/173/4001/1038?maxtoshow=&hits=80&RESULTFORMA T=&fulltext=marihuana&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
397
Neuropsychological effects of marijuana Marihuana Use and Psychosocial Adaptation
(full - 1973) (abst - 1974)
Operant acquisition of marihuana in man.
(abst - 1976)
Cognition and Long-Term Use of Ganja (Cannabis)

http://www.druglibrary.org/schaffer/hemp/medical/cognition.htm
(full - 1981)
Operant acquisition of marihuana by women.
(abst - 1985) (abst 1991) (news - 1992)
http://eurekamag.com/research/006/035/operant-acquisition-marihuana-women.php
Flashback Following Use of Cannabis--a Review THREE THINGS MARIJUANA DOESN'T DO

http://www.ukcia.org/research/mjfaq2.php
60- and 72-month follow-up of children prenatally exposed to marijuana, cigarettes, and alcohol: cognitive and language assessment. (abst 1992)
Cerebellar activity and disturbed time sense after THC.

(abst - 1998)
Cannabis use and cognitive decline in persons under 65 years of age (full - 1999) http://www.ukcia.org/research/CannabisUseAndCognitiveDecline.html Learning impairment produced in rats by the cannabinoid agonist HU 210 in a watermaze task. (abst 1999) http://www.ncbi.nlm.nih.gov/pubmed/10548271 Enhancement of Memory in Cannabinoid Cb1 Receptor Knock-out Mice. (abst 1999)
Neuropsychological Performance in Long-term Cannabis Users
(full - 2001)
http://archpsyc.amaassn.org/cgi/content/full/58/10/909?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&s earchid=1&FIRSTINDEX=2880&resourcetype=HWCIT
398
Current and former marijuana use: preliminary findings of a longitudinal study of effects on IQ in young adults (full - 2002) http://www.cmaj.ca/cgi/content/full/166/7/887 Cognitive Measures in Long-term Cannabis Users.
(abst 2002) (news - 2002)
Heavy cannabis use without long-term effect on global intelligence Marijuana does not dent IQ permanently (news - 2002)
http://www.newscientist.com/article/dn2140-marijuana-does-not-dent-iq-permanently.html

(full 2003)
Non-acute (residual) neurocognitive effects of cannabis use: a meta-analytic study. (abst - 2003) http://www.ncbi.nlm.nih.gov/pubmed/12901774 Study: Brain Not Permanently Damaged by Marijuana (news - 2003)
http://www.drugfree.org/join-together/drugs/study-brain-not-permanently
Minimal Long-Term Effects Of Marijuana Use Found In Central Nervous System By UCSD Researchers (news - 2003)
Heavy Marijuana Use Doesn't Damage Brain

(news - 2003)
Differential Effects of THC or CBD-rich Cannabis Extracts on Working Memory in Rats (full - 2004) http://www.ukcia.org/research/THCCBDWorkingMemory.pdf Marijuana Effects On Human Forgetting Functions (full - 2005)
Early age-related cognitive impairment in mice lacking cannabinoid CB1 receptors. (full 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266095/?tool=pubmed Neurocognitive consequences of marihuana--a comparison with pre-drug performance (abst - 2005) http://marijuana.researchtoday.net/archive/2/2/22.htm Effects of the endocannabinoid noladin ether on body weight, food consumption, locomotor activity, and cognitive index in mice. (abst 2005)
Cannabinoids ameliorate cerebral dysfunction following liver failure via AMP-activated protein kinase (full - 2007) http://hmg.oxfordjournals.org/cgi/content/full/14/22/3389
399
The synthetic cannabinoid HU210 induces spatial memory deficits and suppresses hippocampal firing rate in rats (full 2007)
Acute effects of smoked marijuana on decision making, as assessed by a modified gambling task, in experienced marijuana users (abst - 2007)
http://www.informaworld.com/smpp/content~content=a778611568~db=all
Cannabis Intoxication Does Not Adversely Impact Decision Making (news - 2007) http://www.illinoisnorml.org/content/view/558/27/ The cannabinoid CB1 receptor antagonist CE prolongs spatial memory duration in a rat delayed radial arm maze memory task (full - 2008)
Blunted Psychotomimetic and Amnestic Effects of -9-Tetrahydrocannabinol in Frequent Users of Cannabis (full 2008)

(full - 2008)
Neurocognitive performance during acute THC intoxication in heavy and occasional cannabis users. (abst - 2008)
http://www.unboundmedicine.com/medline/ebm/record/18719045/full_citation/Neurocognitive_performan ce_during_acute_THC_intoxication_in_heavy_and_occasional_cannabis_users_
Review: executive functioning and cannabis use.
(abst - 2008)
http://www.unboundmedicine.com/medline/ebm/record/18373021/abstract/%5BReview:_executive_functi oning_and_cannabis_use_%5D
Marijuana Primes, Marijuana Expectancies, and Arithmetic Efficiency

(full - 2009)
Is moderate substance use associated with altered executive functioning in a populationbased sample of young adults? (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19946940/full_citation/Is_moderate_substance_use _associated_with_altered_executive_functioning_in_a_population_based_sample_of_young_adults
Evaluating the effect of aquatic extraction of Cannabis sativa seed on spatial memory consolidation (abst - 2010) http://www.annals-general-psychiatry.com/content/9/S1/S143
400
Evaluating the effect of Cannabis sativa seed extraction on memory

http://www.annals-general-psychiatry.com/content/9/S1/S208
(abst - 2010)
Influence of cannabis use trajectories, grade repetition and family background on the school-dropout rate at the age of 17 years in France. (abst - 2010)
http://www.unboundmedicine.com/medline/ebm/record/19805506/abstract/Influence_of_cannabis_use_traj ectories_grade_repetition_and_family_background_on_the_school_dropout_rate_at_the_age_of_17_years_ in_France_
Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study: naturalistic study (abst 2010)
http://www.ncbi.nlm.nih.gov/pubmed?term=Impact%20of%20cannabidiol%20on%20the%20acute%20me mory%20and%20psychotomimetic%20effects%20of%20smoked%20cannabis%3A
Opposite Effects of -9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology (abst - 2010)
Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20884951 Key ingredient staves off marijuana memory loss (news - 2010) (news 2010) (news 2010)
Imbalance of Cannabis ChemicalsCauses Memory Issues Key ingredient dilutes marijuana's effect on memory.
http://www.beckleyfoundation.org/2010/10/18/imbalance-of-cannabis-chemicals-causes-memory-issues/
http://www.thefreelibrary.com/Key+ingredient+dilutes+marijuana%27s+effect+on+memory.-a0238532965
Marijuana May Offset Alcohol-Induced Cognitive Impairment Among Teens (news 2010) http://www.norml.org/index.cfm?Group_ID=8378 AM251, cannabinoids receptors ligand, improves recognition memory in rats. (full 2011) http://www.if-pan.krakow.pl/pjp/pdf/2011/3_670.pdf Sex, drugs, and cognition: effects of marijuana. (full 2011)
401
Early onset of aging-like changes is restricted to cognitive abilities and skin structure in Cnr1(-/-) mice. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/20724033 Memory-rescuing effects of cannabidiol in an animal model of cognitive impairment relevant to neurodegenerative disorders. (abst 2011)
Sub-chronic impact of cannabinoids in street cannabis on cognition, psychotic-like symptoms and psychological well-being. (abst 2011)
Combined effects of THC and caffeine on working memory in rats.

(abst 2011)
The Dopamine and Cannabinoid Interaction in the Modulation of Emotions and Cognition: Assessing the Role of Cannabinoid CB1 Receptor in Neurons Expressing Dopamine D1 Receptors. (abst -2011)
Endocannabinoid signaling in the amygdala: anatomy, synaptic signaling, behavior, and adaptations to stress. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21884761 Fish oil promotes survival and protects against cognitive decline in severely undernourished mice by normalizing satiety signals. (abst 2011)
Effects of Chronic Marijuana Use on Brain Activity During Monetary Decision-Making. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21956445 Memory-rescuing effects of cannabidiol in an animal model of cognitive impairment relevant to neurodegenerative disorders. (abst 2011)
Clozapine and SCH 23390 prevent the spatial working memory disruption induced by 9-THC administration into the medial prefrontal cortex. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21281616/abstract/Clozapine_and_SCH_23390_pr event_the_spatial_working_memory_disruption_induced_by_%CE%949_THC_administration_into_the_m edial_prefrontal_cortex_
Effects of endocannabinoid system modulation on cognitive and emotional behavior. (abst 2011) http://marijuana.researchtoday.net/archive/8/9/4801.htm
402
Stoner Stupid Myth Goes Up In Smoke Are smart kids more likely to use drugs?
(news 2011) (news 2011)
http://blog.norml.org/2011/07/27/stonet-stupid-myth-goes-up-in-smoke/
http://news.yahoo.com/smart-kids-more-likely-drugs-160000571.html
High Childhood IQ Linked to Subsequent Illicit Drug Use, Research Suggests (news 2011) http://www.sciencedaily.com/releases/2011/11/111114221018.htm Pot smoking not tied to middle-age mental decline (news 2012)
JWH-015 synthetic, CB2 agonist Effects of cannabinoid receptor agonists on neuronally-evoked contractions of urinary bladder tissues isolated from rat, mouse, pig, dog, monkey and human (full - 2000)
Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation (full - 2005) http://www.jneuroinflammation.com/content/2/1/29 CB2 cannabinoid receptors in trabecular meshwork cells mediate JWH015-induced enhancement of aqueous humor outflow facility. (full - 2005)
CB2 cannabinoid receptor agonist, JWH-015 triggers apoptosis in immune cells: Potential role for CB2 selective ligands as immunosuppressive agents (full 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1864948 / In vivo effects of CB2 receptor-selective cannabinoids on the vasculature of normal and arthritic rat knee joints (full - 2007)
Potential role for CB2 selective ligands as immunosuppressive agents

(full - 2007)
403
CB2 cannabinoid receptor agonist JWH-015 modulates human monocyte migration through defined intracellular signaling pathways. (full 2008)
Behavioral effects of CB2 cannabinoid receptor activation and its influence on food and alcohol consumption. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18991890 Presence and regulation of cannabinoid receptors in human retinal pigment epithelial cells. (full 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697670/?tool=pubmed Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)Methanandamide and JWH-015: Involvement of CB2 (full - 2009)
The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages. (abst - 2009)
Protective effects of the synthetic cannabinoids CP55,940 and JWH-015 on rat brain mitochondria upon paraquat exposure. (abst 2010)
Cannabis chemicals may help fight prostate cancer
(news - 2010)
Crosstalk between Chemokine Receptor CXCR4 and Cannabinoid Receptor CB(2) in Modulating Breast Cancer Growth and Invasion. (full 2011)
Marijuana-based Drugs: Innovative Therapeutics or Designer Drugs of Abuse? (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139381/?tool=pubmed
404
Beyond THC: The New Generation of Cannabinoid Designer Drugs.

(full 2011)
Intrathecal Administration of the Cannabinoid 2 Receptor Agonist JWH015 Can Attenuate Cancer Pain and Decrease mRNA Expression of the 2B Subunit of N-Methyld-Aspartic Acid (abst 2011)
http://www.anesthesiaanalgesia.org/content/early/2011/04/25/ANE.0b013e31821d1062.abstract?maxtoshow=&hits=80&RESUL TFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype=HWC IT
(news 2011)
Chemicals Used in "Spice" and "K2" Type Products Now Under Federal Control and Regulation (news 2011) http://www.justice.gov/dea/pubs/pressrel/pr030111.html Contrasting protective effects of cannabinoids against oxidative stress and amyloid- evoked neurotoxicity in vitro. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/22233683
JWH-018 synthetic, CB1agonist Withdrawal Phenomena and Dependence Syndrome After the Consumption of "Spice Gold" (full - 2009)
Spice drugs: cannabinoids as a new designer drugs.

(abst - 2009)
(abst 2009)
JWH018, a common constituent of 'Spice' herbal blends, is a potent and efficacious cannabinoid CB(1) receptor agonist. (full - 2010)
405
Involvement of cannabinoid-1 and cannabinoid-2 receptors in septic ileus.

(full 2010)
Monitoring of herbal mixtures potentially containing synthetic cannabinoids as psychoactive compounds. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20857386 Chemical analysis of synthetic cannabinoids as designer drugs in herbal products. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20117892 Screening for the synthetic cannabinoid JWH-018 and its major metabolites in human doping controls. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20872894 FAQ: K2, Spice Gold, and Herbal 'Incense' THIS ISN'T YOUR MOTHER'S SPICE (news - 2010) (news - 2010)
http://www.webmd.com/mental-health/news/k2-spice-gold-herbal-incense-faq
College students and use of K2: an emerging drug of abuse in young persons (full 2011) http://www.substanceabusepolicy.com/content/6/1/16 Beyond THC: The New Generation of Cannabinoid Designer Drugs.
(full 2011)
Investigating a not-so-natural high. (full 2011) http://pubs.acs.org/doi/full/10.1021/ac900564u Marijuana-based Drugs: Innovative Therapeutics or Designer Drugs of Abuse? (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139381/?tool=pubmed Liquid chromatography-tandem mass spectrometry analysis of urine specimens for K2 (JWH-018) metabolites. (full 2011)
Synthetic cannabinoid JWH-018 and psychosis: An explorative study.

(abst 2011)
Cardiotoxicity associated with the synthetic cannabinoid, K9, with laboratory confirmation. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21802885 Synthetic cannabinoids in oral fluid.
(abst 2011) (abst 2011)

Comparison of "herbal highs" composition.

(abst 2011)
406
"Spice" girls: synthetic cannabinoid intoxication.

(abst 2011)
Three cases of "spice" exposure.
(abst 2011) (abst 2011)
Severe toxicity following synthetic cannabinoid ingestion.


Quantitative measurement of JWH-018 and JWH-073 metabolites excreted in human urine . (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21506519 1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/22127210/abstract/1_Pentyl_3_phenylacetylindole s_and_JWH_018_share_in_vivo_cannabinoid_profiles_in_mice_

(news 2011)
'Fake Marijuana' May Trigger Heart Trouble in Teens
(news 2011)
JWH-018 and JWH-073: {Delta}9-Tetrahydrocannabinol-Like Discriminative Stimulus Effects in Monkeys. (abst 2012)
407
JWH-073 - synthetic, CB1 & CB2 agonist Spice drugs: cannabinoids as a new designer drugs. (abst - 2009)
(abst 2009)
Marijuana-based Drugs: Innovative Therapeutics or Designer Drugs of Abuse? (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139381/?tool=pubmed Chemical analysis of synthetic cannabinoids as designer drugs in herbal products. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20117892 Monitoring of herbal mixtures potentially containing synthetic cannabinoids as psychoactive compounds. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20857386 Now, There's a Test for That -- Norchem's "Fake Marijuana" Test Reveals Significantly Increased Abuse of Spice/K2 (news - 2010)
College students and use of K2: an emerging drug of abuse in young persons (full 2011) http://www.substanceabusepolicy.com/content/6/1/16 Beyond THC: The New Generation of Cannabinoid Designer Drugs.
(full 2011)
CP47,497-C8 and JWH073, commonly found in 'Spice' herbal blends, are potent and efficacious CB(1) cannabinoid receptor agonists. (abst 2011)

(abst 2011)
(abst 2011)
Cardiotoxicity associated with the synthetic cannabinoid, K9, with laboratory confirmation. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21802885 Synthetic cannabinoid JWH-018 and psychosis: an explorative study.
(abst 2011)

(abst 2011)
408
(abst 2011)
Quantitative measurement of JWH-018 and JWH-073 metabolites excreted in human urine. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21506519 Latest blood test detects 12 popular synthetic cannabinoids in "fake pot". (news 2011)
(news 2011)
Chemicals Used in "Spice" and "K2" Type Products Now Under Federal Control and Regulation (news 2011) http://www.justice.gov/dea/pubs/pressrel/pr030111.html JWH-018 and JWH-073: {Delta}9-Tetrahydrocannabinol-Like Discriminative Stimulus Effects in Monkeys. (abst 2012)
JWH-100 / AM -678 - synthetic, CB1 agonist College students and use of K2: an emerging drug of abuse in young persons (full 2011) http://www.substanceabusepolicy.com/content/6/1/16 Chemicals Used in "Spice" and "K2" Type Products Now Under Federal Control and Regulation (news 2011) http://www.justice.gov/dea/pubs/pressrel/pr030111.html
JWH-133/ 3-(1_1_-dimethylbutyl)- 1-deoxy-_8-THC - synthetic, CB2 agonist Inhibition of tumor angiogenesis by cannabinoids (full - 2003)
409
Signaling pathways involved in the cardioprotective effects of cannabinoids. (full - 2006) http://www.jstage.jst.go.jp/article/jphs/102/2/155/_pdf Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228252/?tool=pmcentrez Cannabinoids Induce Glioma Stem-like Cell Differentiation and Inhibit Gliomagenesis (full - 2007) http://www.jbc.org/content/282/9/6854.long Anti-inflammatory property of the cannabinoid receptor-2-selective agonist JWH-133 in a rodent model of autoimmune uveoretinitis (full - 2007)
http://www.jleukbio.org/cgi/reprint/82/3/532?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=canna binoid&searchid=1&FIRSTINDEX=240&resourcetype=HWCIT
Influence of nicotinic receptor modulators on CB2 cannabinoid receptor agonist (JWH133)-induced antinociception in mice. (abst 2007)
410
Cannabinoid 2 receptor induction by IL-12 and its potential as a therapeutic target for the treatment of anaplastic thyroid carcinoma. (abst - 2008)
Activation of the cannabinoid 2 receptor (CB2) protects against experimental colitis. (full - 2009) http://onlinelibrary.wiley.com/doi/10.1002/ibd.20960/full Cannabinoid CB2 Receptor Potentiates Obesity-Associated Inflammation, Insulin Resistance and Hepatic Steatosis (full - 2009)
(full - 2009)
Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer (full - 2009) http://mct.aacrjournals.org/content/8/11/3117.full CB2 cannabinoid receptor activation is cardioprotective in a mouse model of ischemia/reperfusion (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19162037 Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917429/?tool=pmcentrez Activation of cannabinoid 2 receptors protects against cerebral ischemia by inhibiting neutrophil recruitment. (full 2010) http://www.fasebj.org/content/24/3/788.long Cannabidiol and other cannabinoids reduce microglial activation in vitro and in vivo: relevance to Alzheimers' disease (full 2011)
Brain cannabinoid CB2 receptors modulate cocaine's actions in mice

(abst 2011)
Atheroprotection via cannabinoid receptor-2 is mediated by circulating and vascular cells in vivo. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21884703 Antinociceptive effects induced through the stimulation of spinal cannabinoid type 2 receptors in chronically inflamed mice (abst - 2011)
Cannabinoid receptor-2 (CB2) agonist ameliorates colitis in IL-10(-/-) mice by attenuating the activation of T cells and promoting their apoptosis. (abst 2011)
411
Beneficial paracrine effects of cannabinoid receptor 2 on liver injury and regeneration. (abst 2011)
Spinal cannabinoid CB2 receptors as a target for neuropathic pain: an investigation using chronic constriction injury. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22210507 Cannabinoid type 2 receptor activation downregulates stroke-induced classic and alternative brain macrophage/microglial activation concomitant to neuroprotection. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/22020035
KIDNEYS Cream with endocannabinoids effective in the treatment of pruritus due to kidney disease (news - 2005) http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=207 Modulation of P-glycoprotein activity by cannabinoid molecules in HK-2 renal cells (full - 2006) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1751877&tool=pmcentrez Regulation of Bone Mass, Osteoclast Function, and Ovariectomy-Induced Bone Loss by the Type 2 Cannabinoid Receptor (full - 2008)
The preventive effect of cannabinoids on reperfusion-induced ischemia of mouse kidney. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18571910 Ajulemic acid, a synthetic cannabinoid, increases formation of the endogenous proresolving and anti-inflammatory eicosanoid, lipoxin A4 (full - 2009)
Cannabinoid Receptor 1 Blockade Ameliorates Albuminuria in Experimental Diabetic Nephropathy (full 2010)
http://diabetes.diabetesjournals.org/content/59/4/1046.full?sid=0bc8e3fa-5275-4b19-8acc-4aec5dfac384
Cannabinoid-2 receptor limits inflammation, oxidative/nitrosative stress, and cell death in nephropathy. (full 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869084/?tool=pubmed Expression of cannabinoid receptors in human kidney.
(abst 2010)
412
Protective Role of Cannabinoid Receptor Type 2 in a Mouse Model of Diabetic Nephropathy. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21810593 Distinctive effects of plant protein sources on renal disease progression and associated cardiac hypertrophy in experimental kidney disease. (abst 2011)
Is there a legitimate role for the therapeutic use of cannabinoids for symptom management in chronic kidney disease? (abst 2011)
Cannabinoid hyperemesis syndrome inducing acute prerenal failure and electrolyte disturbance. (abst 2011)
KNOCK-OUT MICE they show what can happen when the endocannabinoid system is defective. Increased Mortality, Hypoactivity, and Hypoalgesia in Cannabinoid Cb1 Receptor Knockout Mice. (full 1999) http://www.pnas.org/content/96/10/5780.long Enhancement of Memory in Cannabinoid Cb1 Receptor Knock-out Mice. (abst 1999)
Are Cannabinoid Receptor Knockout Mice Animal Models for Schizophrenia? (abst - 2000) http://www.medical-hypotheses.com/article/S0306-9877%2800%2991261-1/abstract The Central Cannabinoid Receptor Inactivation Suppresses Endocrine Reproductive Functions. (abst 2001)
Lack of CB1 cannabinoid receptors modifies nicotine behavioural responses, but not nicotine abstinence. (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/12384171
413
Milk intake and survival in newborn cannabinoid CB1 receptor knockout mice: evidence for a "CB3" receptor. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12568912 Cannabinoid Cb1 Receptor Knockout Mice Exhibit Markedly Reduced Voluntary Alcohol Consumption and Lack Alcohol-induced Dopamine Release in the Nucleus Accumbens. (abst 2003)
http://medical-journals.healia.com/doc/12562514/Cannabinoid-CB1-receptor-knockout-mice-exhibitmarkedly-reduced-voluntary-alcohol-consumption-and-lack-alcohol-induced-dopamine-release-in-thenucleus-accumbens
Defective adult neurogenesis in CB1 cannabinoid receptor knockout mice.

(full - 2004)
CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity (full - 2004)
Early age-related cognitive impairment in mice lacking cannabinoid CB1 receptors. (full 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266095/?tool=pubmed Cannabinoid-receptor 1 null mice are susceptible to neurofilament damage and caspase 3 activation. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/15953683 Involvement of Neuronal Cannabinoid Receptor CB1 in Regulation of Bone Mass and Bone Remodeling (full - 2006)

(full - 2008)
The peripheral cannabinoid receptor knockout mice: an update. (full 2008)

Turned-Off Cannabinoid Receptor Turns On Colorectal Tumor Growth

(news - 2008)
414
Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease. (abst 2009)
CB2 receptor activation attenuates microcirculatory dysfunction during cerebral ischemic/reperfusion injury. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19332079 Genes differentially expressed in CB1 knockout mice: involvement in the depressive-like phenotype. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20692131 WIN55212-2 ameliorates atherosclerosis associated with suppression of proinflammatory responses in ApoE-knockout mice. (abst 2010)
Effects of chronic nicotine on food intake and anxiety-like behaviour in CB(1) knockout mice. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20189358 Role of CB1 cannabinoid receptors on GABAergic neurons in brain aging
(full 2011)
Early onset of aging-like changes is restricted to cognitive abilities and skin structure in Cnr1(-/-) mice. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/20724033 Comparative effects of chlorpyrifos in wild type and cannabinoid Cb1 receptor knockout mice. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21672545 The role of cannabinoid receptors in bone remodeling in a CB1/2 double knockout mouse (abst 2011)
http://www.fasebj.org/cgi/content/meeting_abstract/25/1_MeetingAbstracts/492.5?maxtoshow=&hits=80& RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=160&sortspec=date&resourcety pe=HWCIT
Impaired hippocampal glucoregulation in the cannabinoid CB(1) receptor knockout mice as revealed by an optimized in vitro experimental approach. (abst 2011)
Upregulation of cannabinoid type 1 receptors in dopamine D2 receptor knockout mice is reversed by chronic forced ethanol consumption. (full 2012)
LEGIONAIRES DISEASE Legionnaires disease in cannabis smokers. (abst 2011)

http://www.unboundmedicine.com/medline/ebm/record/20923802/abstract/Legionnaires_disease_in_canna bis_smokers_
415
LEISHMANIASIS Biologically Active Cannabinoids from High-Potency Cannabis sativa. (abst - 2009)
LIVER DISEASE - NON HEPATITIS - also see HEPATITIS HEMP AS A MEDICAMENT : Importance of hemp seeds in the tuberculosis therapy (Forum thread- full- 1955) (EDEZYME. recipe)
Preliminary observation with dronabinol in patients with intractable pruritus secondary to cholestatic liver disease. (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/12190187 A Novel Synthetic Cannabinoid Derivative Inhibits Inflammatory Liver Damage via Negative Cytokine Regulation (full - 2003)
http://molpharm.aspetjournals.org/content/64/6/1334.full
The cannabinoid agonist WIN 55, 212-2 increases nociception threshold in cholestatic rats: implications for the treatment of the pruritus of cholestasis. (abst 2003)
Pathogenesis and treatment of pruritus in patients with cholestasis

(abst 2003)
Treatment of the Pruritus of Cholestasis.

(abst 2004) (full - 2005) (full - 2005)
The endocannabinoid system in chronic liver disease

http://www.medigraphic.com/pdfs/hepato/ah-2005/ah054c.pdf
(Marijuana/Hash) Endocannabinoids and liver disease - review

http://www.natap.org/2005/HCV/091905_01.htm
416
Roles of anandamide in the hepatic microcirculation in cirrhotic rats
(full 2005)
The Ffa Receptor Gpr40 Links Hyperinsulinemia, Hepatic Steatosis, and Impaired Glucose Homeostasis in Mouse. (abst 2005)
Antifibrogenic role of the cannabinoid receptor CB2 in the liver.

(abst 2005)
CB2 receptors as new therapeutic targets for liver diseases

(full - 2007)
Cannabinoid-2 receptor agonist HU-308 protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and apoptosis (full - 2007) http://www.jleukbio.org/cgi/content/full/82/6/1382 Cannabinoids ameliorate cerebral dysfunction following liver failure via AMP-activated protein kinase (full - 2007) http://hmg.oxfordjournals.org/cgi/content/full/14/22/3389 Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats (full - 2007)
Pivotal Advance: Cannabinoid-2 receptor agonist HU-308 protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and apoptosis (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225476/?tool=pmcentrez Anandamide inhibits cholangiocyte hyperplastic proliferation via activation of thioredoxin 1/redox factor 1 and AP-1 activation (full 2007)
http://ajpgi.physiology.org/content/294/2/G506.full
Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228252/?tool=pmcentrez Cannabinoid receptors as new targets of antifibrosing strategies during chronic liver diseases. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17952109 Cannabinoid receptors as novel therapeutic targets for the management of non-alcoholic steatohepatitis (full - 2008) http://www.em-consulte.com/article/200095 CB2 receptors as new therapeutic targets for liver diseases.
(full - 2008)
Role of cannabinoids in chronic liver diseases

http://www.wjgnet.com/1007-9327/full/v14/i40/6109.htm
(full 2008)
417
Endocannabinoids and Liver Disease. I. Endocannabinoids and their receptors in the liver (full 2008)
http://ajpgi.physiology.org/content/294/1/G9.full?sid=872637e5-97b2-4103-aaf0-b3e8f6f0eb64
Endocannabinoids and Liver Disease. II. Endocannabinoids in the pathogenesis and treatment of liver fibrosis (full 2008)
http://ajpgi.physiology.org/content/294/2/G357.full?sid=872637e5-97b2-4103-aaf0-b3e8f6f0eb64
Endocannabinoids and Liver Disease. IV. Endocannabinoid involvement in obesity and hepatic steatosis (full - 2008) http://ajpgi.physiology.org/cgi/content/full/294/5/G1101 Endocannabinoids and Liver Disease. V. Endocannabinoids as mediators of vascular and cardiac abnormalities in cirrhosis (full 2008)
(full 2008)
Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects (full 2008) http://gut.bmj.com/content/57/8/1140.full Endocannabinoids and cannabinoid receptors in ischaemiareperfusion injury and preconditioning (full - 2008)
Cannabinoids and capsaicin improve liver function following thioacetamide-induced acute injury in mice. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/19086956 Endocannabinoids in liver disease and hepatic encephalopathy. (abst 2008)
The endocannabinoid system as a novel target for the treatment of liver fibrosis (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/17412522 Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects (abst - 2008) http://gut.bmj.com/content/57/8/1140.abstract
418
Systematic review and meta-analysis on the adverse events of rimonabant treatment: Considerations for its potential use in hepatology (full - 2009)
http://www.biomedcentral.com/1471-230X/9/75
(full - 2009)
Cannabidiol ameliorates cognitive and motor impairments in mice with bile duct ligation. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19596476/abstract/Cannabidiol_ameliorates_cogni tive_and_motor_impairments_in_mice_with_bile_duct_ligation_
Science: Oral intake of a cannabinoid together with a meal improved bioavailability by avoiding first-pass metabolism (abst - 2009)
The role of CB2 cannabinoid receptor and Leptin in hepatic fibrosis via lymphocyte alterations and HSC phagocytosis (abst 2009)

Recent advances in the understanding of the role of the endocannabinoid system in liver diseases. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20934397 Role of the endocannabinoid system in alcoholic liver disease.
(abst 2010)
Endocannabinoids in liver disease.
(full 2011)
Cannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis. (full 2011)
419
Cannabidiol, a Major Phytocannabinoid, as a Potent Atypical Inhibitor for Cytochrome P450 2D6. (full 2011)
http://dmd.aspetjournals.org/content/early/2011/08/05/dmd.111.041384.long
Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21704641/abstract/Identification_of_cytochrome_ P450_enzymes_responsible_for_metabolism_of_cannabidiol_by_human_liver_microsomes_
Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and cell death (abst 2011)
Therapeutic potential of cannabidiol against ischemia/reperfusion liver injury in rats. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21930120 Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver (abst 2011)
http://www.pnas.org/content/108/15/6323.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fulltext= cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype=HWCIT
Cannabinoid CB2 receptors protect against alcoholic liver disease by regulating kupffer cell polarization in mice. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21735467 Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice. (abst 2011)
Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21362471/abstract/Cannabidiol_protects_against_h epatic_ischemia/reperfusion_injury_by_attenuating_inflammatory_signaling_and_response_oxidative/nitra tive_stress_and_cell_death_
(8) -Tetrahydrocannabivarin protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress and inflammatory response involving CB(2) receptors. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21470208 Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21383171/abstract/Hyperactivation_of_anandamid e_synthesis_and_regulation_of_cell_cycle_progression_via_cannabinoid_type_1__CB1__receptors_in_the _regenerating_liver_
420
A new cannabinoid 2 receptor agonist HU-910 attenuates oxidative stress, inflammation, and cell death associated with hepatic ischemia/reperfusion injury. (abst 2011)
Therapeutic potential of cannabidiol against ischemia/reperfusion liver injury in rats. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21930120 Beneficial paracrine effects of cannabinoid receptor 2 on liver injury and regeneration. (abst 2011)
Cannabis Compound Induces Death Of Cells Associated With Liver Fibrosis (news 2011) http://www.norml.org/index.cfm?Group_ID=8615 Marijuana Compound Improves Brain And Liver Function In Animal Model Of Hepatic Encephalopathy (news 2011) http://www.norml.org/index.cfm?Group_ID=8464
LONG TERM USE EFFECTS Ganja in Jamaica (book 1976) http://www.cifas.us/cannabis/PDFs/OCRGanjainJamaica.pdf Cognition and Long-Term Use of Ganja (Cannabis)
(full - 1981)
Neurological and neuroradiological examination of chronic cannabis smokers. (abst 1983) http://www.ncbi.nlm.nih.gov/pubmed/6830182 Long-Term Marijuana Users Suffer Few Health Problems, Australian Study Indicates (news - 1997) http://www.ukcia.org/research/aus.htm Long-term cannabis use: characteristics of users in an Australian rural area. (abst - 1998) http://www.ncbi.nlm.nih.gov/pubmed/9744119 Neuropsychological Performance in Long-term Cannabis Users (full - 2001)
http://archpsyc.amaassn.org/cgi/content/full/58/10/909?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&s earchid=1&FIRSTINDEX=2880&resourcetype=HWCIT
The pharmacologic effects of daily marijuana smoking in humans

(abst - 2002)
Cognitive Measures in Long-term Cannabis Users.

(abst 2002)
421
17. LONG-TERM EFFECTS OF HEAVY MARIJUANA USE

http://scienceweek.com/2002/sw020426.htm
(news - 2002)
Heavy Marijuana Use Doesn't Damage Brain
(news 2003)
http://www.webmd.com/mental-health/news/20030701/heavy-marijuana-use-doesnt-damage-brain
Minimal Long-Term Effects Of Marijuana Use Found In Central Nervous System By UCSD Researchers (news - 2003)
Survey of Australians using cannabis for medical purposes
(full - 2005)
Long-term use of a cannabis-based medicine in the treatment of spasticity and other symptoms in multiple sclerosis. (abst 2006)
Long term marijuana users seeking medical cannabis in California (2001-2007): demographics, social characteristics, patterns of cannabis and other drug use of 4117 applicants. (full - 2007)
Protracted cannabinoid administration elicits antidepressant behavioral responses in rats: role of gender and noradrenergic transmission. (abst - 2009)
The morphology of the immune system in opiomania, cannabism, and polynarcotism (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19938701/full_citation/%5BThe_morphology_of_t he_immune_system_in_opiomania_cannabism_and_polynarcotism%5D
Effects of cannabis on lung function: a population-based cohort study.

(full - 2010)
Marijuana use among older adults in the U.S.A.: user characteristics, patterns of use, and implications for intervention (abst 2011)
422
Popular intoxicants: what lessons can be learned from the last 40 years of alcohol and cannabis regulation? (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21926420 125 Year Old Woman Claimed Smoking Cannabis Everyday Was Her Secret to Long Life (news 2011)
Pot smoking not tied to middle-age mental decline
(news 2012) (news 2012)
One Joint a Week for 49 Years Doesnt Harm Lungs, Research Finds
http://www.businessweek.com/news/2012-01-13/one-joint-a-week-for-49-years-doesn-t-harm-lungsresearch-finds.html
LUNG FUNCTION Byssinosis, Chronic Bronchitis, and Ventilatory Capacities in Workers Exposed to Soft Hemp Dust (full - 1968)
Bronchodilator effect of delta1-tetrahydrocannabinol.

(full - 1978)
Acute Effects of Marihuana Smoking on Maximal Exercise Performance. (abst 1986)

http://medical-journals.healia.com/doc/3097453/Acute-effects-of-marihuana-smoking-on-maximalexercise-performance
No increase in carcinogen-DNA adducts in the lungs of monkeys exposed chronically to marijuana smoke. (abst 1992) http://www.ncbi.nlm.nih.gov/pubmed/1488780 Health care use by frequent marijuana smokers who do not smoke tobacco. (full - 1993)
Exogenous lipid pneumonia related to smoking weed oil following cadaveric renal transplantation (abst, link to full - 2000) http://www.ncbi.nlm.nih.gov/sites/pubmed Cannabinoids and the immune system. Of men, mice and cells
(abst 2004)
423
Bullous disease of the lung and cannabis smoking: insufficient evidence for a causative link (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1360494/?tool=pmcentrez Effects of Marijuana Smoking on Pulmonary Function and Respiratory Complications: A Systematic Review (full - 2007)
No Decrease in Pulmonary Function Associated with Long-Term Cannabis Smoking, Study Says (news - 2007) http://www.illinoisnorml.org/content/view/366/27/ Cannabinoid CB(2) receptor activation prevents bronchoconstriction and airway oedema in a model of gastro-oesophageal reflux. (abst - 2007)
"Bong lung" in cystic fibrosis: a case report
(full - 2010)
Effects of cannabis on lung function: a population-based cohort study. (full - 2010)

Marijuana doesn't harm lung function, study found
(news 2012) (news - 2012) (news 2012)
http://news.yahoo.com/marijuana-doesnt-harm-lung-function-study-found-210146886.html
Marijuana Smoke Not as Damaging as Tobacco, Says Study
One Joint a Week for 49 Years Doesnt Harm Lungs, Research Finds
http://www.businessweek.com/news/2012-01-13/one-joint-a-week-for-49-years-doesn-t-harm-lungsresearch-finds.html
LUPUS ERYTHEMATOSUS Systemic Lupus Erythematosus by Lisa Swiderski

http://rxmarijuana.com/lupus.htm
(anecdotal - no date)
Lupus by Randi Cox
(anecdotal no date) (news - 2003)
http://rxmarijuana.com/shared_comments/lupus2.htm
Cannabis May Suppress Immune System Systemic Lupus by Dawn
(anecdotal - 2005)
http://www.erowid.org/experiences/exp.php?ID=49481
Suppression of human macrophage interleukin-6 by a nonpsychoactive cannabinoid acid. (abst - 2008) http://www.ncbi.nlm.nih.gov/sites/pubmed
424
Plaquenil, Rheumatoid Arthritis, Lupus and Marijuana (Cannabis)
(news 2010)
http://www.mcsocal.com/blog/plaquenil-rheumatoid-arthritis-lupus-and-marijuana-cannabis
LYME DISEASE Lyme Disease by Cynkay Morningstar (anecdotal no date)

http://rxmarijuana.com/shared_comments/Lyme_Disease.htm
Cannabis Alleviates Symptoms of Lyme Disease! (news 2010)

http://ezinearticles.com/?Cannabis-Alleviates-Symptoms-of-Lyme-Disease!&id=4979819
MACULAR DEGENERATION Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration. (abst 2006)
Mediation of Cannabidiol Anti-inflammation in the Retina by Equilibrative Nucleoside Transporter and A2A Adenosine Receptor (full 2008)
Presence and regulation of cannabinoid receptors in human retinal pigment epithelial cells. (full 2009)
MAD COW/ CRUETZFELDT-JACOB DISEASE also see PRIONS Nonpsychoactive Cannabidiol Prevents Prion Accumulation and Protects Neurons against Prion Toxicity (full - 2007) http://www.jneurosci.org/cgi/content/full/27/36/9537 Recent News: Marijuana (Cannabis) May Prevent Mad Cow Disease (news - 2007) http://www.evilmamacow.org/marijuana-prevents-mad-cow-disease.php Cannabidiol May be Effective in Preventing Bovine Spongiforme Enzephalopathy (Mad Cow Disease) (news - 2007) http://www.letfreedomgrow.com/articles/fr070916.htm
425
Pot Compound Protective Against Mad Cow Disease, Other Fatal Brain Disorders, Study Says (news - 2007) http://www.norml.org/index.cfm?Group_ID=7362 Pot smoking could stop Mad Cow Disease? (news - 2008)
http://chattahbox.com/curiosity/2008/12/06/pot-smoking-could-stop-mad-cow-disease/
MARINOL- a synthetic THC - also see DRONABINOL Cannabinoids (encyclopedia entry)

CANNABIS AND MARINOL IN THE TREATMENT OF MIGRAINE HEADACHE (letter - no date) http://www.druglibrary.org/schaffer/hemp/migrn2.htm Chronic Migraine Headache: five cases successfully treated with Marinol and/or illicit cannabis. (abst - 1991) http://www.druglibrary.org/schaffer/hemp/migrn1.htm Abuse potential of dronabinol (Marinol).
(abst 1998) (book excerpt - 2001)
Chapter 3: Cannabis and Marinol Compared Healing Haze? (news - 2001)
http://www.or-coast.net/contigo/PDF%201%20Files/chpt_3.pdf http://www.scientificamerican.com/article.cfm?id=healing-haze
The Role of Cannabis and Cannabinoids in Pain Management

(full 2002)
Marinol Death Sentence: Oregon Man Denied Liver Transplant Because of Prescription - He's Not the Only One (news 2003)
http://stopthedrugwar.org/chronicle-old/299/notransplant.shtml
MARINOL (Dronabinol) Capsules Marinol vs Natural Cannabis
(monograph - 2004)
http://www.fda.gov/ohrms/dockets/dockets/05n0479/05N-0479-emc0004-04.pdf
(full - 2005)
http://www.norml.org/pdf_files/NORML_Marinol_vs_Natural_Cannabis.pdf
Testimony of Terry Jacobs to FDA - why he prefers for medical marijuana to Marinol (news/anecdotal - 2005)
http://www.examiner.com/examiner/x-19678-Cannabis-Revolution-Examiner~y2009m11d5-Testimony-ofTerry-Jacobs-to-FDA--why-he-prefers-for-medical-marijuana-to-Marinol
Big Pharma's Strange Holy Grail: Cannabis Without Euphoria?

(news - 2006)
426
ACG: Cannabinoid Activator Mellows Out Colon

http://www.medpagetoday.com/MeetingCoverage/ACG/4410
(news - 2006) (full -2008)
Medical use of cannabinoids does not cause an increase in serious adverse health effects (news - 2008) http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=272 Deaths from Marijuana v. 17 FDA-Approved Drugs (full- 2009)
http://medicalmarijuana.procon.org/view.resource.php?resourceID=145
Emerging strategies for exploiting cannabinoid receptor agonists as medicines. (full 2009) http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2008.00048.x/full Does the Pot Pill Work? (news - 2009)
http://www.cbsnews.com/stories/2009/08/03/health/main5209380.shtml
The FDA has written documentation that patients can overdose on Marinol and that it can be lethal (news - 2009)
Nature's (Legal) Cannabinoids
(news - 2010)
Oral THC Reduces Aggressive Behavior In Patients With Refractory Psychosis, Study Says (news - 2010) http://www.norml.org/index.cfm?Group_ID=8419 Is Pot Good For You? (news 2011)
http://www.time.com/time/magazine/article/0,9171,1003570,00.html
MDA 19 synthetic, strong CB2 agonist Design and synthesis of a novel series of N-alkyl isatin acylhydrazone derivatives that act as selective cannabinoid receptor 2 agonists for the treatment of neuropathic pain. (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/18666769 Pharmacological characterization of a novel cannabinoid ligand, MDA19, for treatment of neuropathic pain. (full 2010) http://www.anesthesia-analgesia.org/content/111/1/99.long Studies demonstrate analgesic properties of synthetic cannabinoid (news 2010)
http://www.news-medical.net/news/20100702/Studies-demonstrate-analgesic-properties-of-syntheticcannabinoid.aspx
427
MEIGE'S SYNDROME Treatment of Meige's syndrome with cannabidiol. (abst - 1984)

Open label evaluation of cannabidiol in dystonic movement disorders. (full - 1986) http://web.acsalaska.net/~warmgun/es017.html
MEMORY- see IQ
MENIERE'S SYNDROME Menires Syndrome by Charlie Ritchie (anecdotal - no date)

http://www.rxmarijuana.com/shared_comments/ritchie.htm
Doctors say cannabis treats Menieres disease (news - 2005)

http://cannablog.wordpress.com/2006/09/30/doctors-say-cannabis-treats-menieres-disease/
MENINGITIS A novel nonpsychotropic cannabinoid, HU-211, in the treatment of experimental pneumococcal meningitis.
http://jid.oxfordjournals.org/content/173/3/735.long
MENOPAUSE -also see AGING, GYNOCOLOGY Acute effects of marihuana on luteinizing hormone in menopausal women. (abst 1985)
428
Effects of acute marijuana smoking in post-menopausal women.

(abst 1986)
Regulation of Gonadotropin-Releasing Hormone Secretion by Cannabinoids (full - 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1237039/?tool=pmcentrez Regulation of Bone Mass, Osteoclast Function, and Ovariectomy-Induced Bone Loss by the Type 2 Cannabinoid Receptor (full - 2008)
Study: Marijuana & The Fountain of Youth
(news/ad - 2008)
http://reddressdiary.blogspot.com/2008/07/study-marijuana-fountain-of-youth.html
The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/21069097
MENTAL DISORDERS - see SCHIZOPHRENIA/ MENTAL DISORDERS
METHODS OF USE BREATH STRIPS THE GREAT CALIFORNIA WEED RUSH

http://www.mapinc.org/norml/v07/n150/a04.htm
(news - 2007)
US Patent Application 20060039959 - Film-Shaped Mucoadhesive Administration Forms For Administering Cannabis Agents (full 2006)
THC Breath Strips Are Here, And They Are Amazing! Recipe for Breath Strips (forum post- #3 2009)
(anecdotal/news 2008)
http://current.com/green/89636302_thc-breath-strips-are-here-and-they-are-amazing.htm
http://boards.cannabis.com/concentrates/174379-re-creating-thc-strips-home.html
429
METHODS OF USE CAPSULES Herbal Intoxication: Psychoactive Effects From Herbal Cigarettes, Tea, and Capsules (full - 1976)
http://jama.amaassn.org/cgi/reprint/236/5/473?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuana&searchi d=1&FIRSTINDEX=240&resourcetype=HWCIT
Comparison of smoked marijuana and oral Delta(9)-tetrahydrocannabinol in humans. (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/12457271 Fred's THC Capsules Home-made Mari-pills (forum thread - 2008) (forum thread - 2009)
http://www.greenpassion.org/showthread.php?t=4012
METHODS OF USE DECARBOXYLATION a method to increase potency Decarboxylation step-by-step decarboxylation

http://theweedscene.com/decarboxilation/
(article- no date) (news 2001)
Why should cannabis products be heated before eating?

http://www.cannabis-med.org/english/faq/12-heating.htm
Decarboxylation
(news - 2003) (news 2008) (news 2010)
Cooking with Cannabis THC Decarboxylation
http://www.papakief.com/2010/09/cooking-with-cannabis.html
http://420tainment.com/2010/03/decarboxylation-science-smoking/
How-to: Paleo's Potent Decarboxylated Cannabis Oil (Edibles Technique) (forum post 2011)
http://boards.cannabis.com/recipes/194281-how-paleos-potent-decarboxylated-cannabis-oil-ediblestechnique.html
METHODS OF USE- E-CIGARETTES E-Cigarettes: A How-To With Canna (forum post - 2010)
http://forum.grasscity.com/toking-tools/702027-e-cigarettes-how-canna.html
430
METHODS OF USE - EDIBLES Plasma delta-9-tetrahydrocannabinol concentrations and clinical effects after oral and intravenous administration and smoking (abst - 1980)
http://www.nature.com/clpt/journal/v28/n3/abs/clpt1980181a.html
Marijuana-Laced Brownies: Behavioral Effects, Physiologic Effects, and Urinalysis in Humans Following Ingestion (full 1988)
http://docstore.ingenta.com/cgibin/ds_deliver/1/u/d/ISIS/66725041.1/pres/jat/1988/00000012/00000004/art00001/326C346C81BA765A1 326770337BF166BCAB593B4E5.pdf?link=http://www.ingentaconnect.com/error/delivery&format=pdf
Marijuana and chocolate.
(abst - 1996)
Cannabis Cookies: a Cause of Coma.

(abst 1996) (abst 1998)
Trick or treat from food endocannabinoids?
High-performance liquid chromatographic determination of delta9-tetrahydrocannabinol and the corresponding acid in hemp containing foods with special regard to the fluorescence properties of delta9-tetrahydrocannabinol. (abst 2000)
GC-MS analysis of the total delta9-THC content of both drug- and fiber-type cannabis seeds. (abst 2000) http://www.ncbi.nlm.nih.gov/pubmed/11110027 Cannabis Use As Described by People with Multiple Sclerosis.
http://cjns.metapress.com/content/5mw9rpyxvtpjrwf1/fulltext.pdf
(full 2003)
A good pizza joint
(news - 2005)
http://www.bmj.com/cgi/content/full/330/7492/670?maxtoshow=&hits=80&RESULTFORMAT=&fulltext =cannabis&searchid=1&FIRSTINDEX=2960&resourcetype=HWCIT
Delirium following ingestion of marijuana present in chocolate cookies

http://www.cnsspectrums.com/aspx/articledetail.aspx?articleid=357
(full - 2006)
Anti-inflammatory cannabinoids in diet Cooking with Cannabis
(full - 2008)
(news 2008)
http://www.papakief.com/2010/09/cooking-with-cannabis.html
431
Inadvertent ingestion of marijuana - Los Angeles, California, 2009

http://www.gov/mmwr/preview/mmwrhtml/mm5834a2.htm
(full - 2009)
Science: Oral intake of a cannabinoid together with a meal improved bioavailability by avoiding first-pass metabolism (abst - 2009)
Intestinal lymphatic transport enhances the post-prandial oral bioavailability of a novel cannabinoid receptor agonist via avoidance of first-pass metabolism. (abst - 2009)
Accidental cannabis poisoning in children: experience of the Marseille poison center (abst 2009) http://www.ncbi.nlm.nih.gov/pubmed/19541448 US Patent Application 20110097283 - CHEWING GUM COMPOSITIONS COMPRISING CANNABINOIDS (full 2011)
Simultaneous determination of delta-9-tetrahydrocannabinol cannabidiol and cannabinol in edible oil using ultra performance liquid chromatography-tandem mass spectrometry (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21381415/abstract/%5BSimultaneous_determinati on_of_delta_9_tetrahydrocannabinol_cannabidiol_and_cannabinol_in_edible_oil_using_ultra_performance _liquid_chromatography_tandem_mass_spectrometry%5D_
Accidental cannabis poisoning in children: report of four cases in a tertiary care center from southern Spain (abst 2011)
BEVERAGES How to Make Hemp Milk (article no date)

http://www.ehow.com/how_5609776_make-hemp-milk.html
Herbal Intoxication: Psychoactive Effects From Herbal Cigarettes, Tea, and Capsules (abst- 1976) http://www.ncbi.nlm.nih.gov/pubmed/947067
432
Concentration of Marijuana Metabolites in the Urine After Ingestion of Hemp Seed Tea. (abst - 1999)
Cuppa Gives A Better 'ooh'
(news - 2006) (abst - 2007)
http://www.thehempire.com/index.php/cannabis/news/cuppa_gives_a_better_ooh
Cannabis tea revisited: A systematic evaluation
Hemp Seeds, One of the Ways to Rebalance and Detox Your Body
(news 2008)
http://www.thefreelibrary.com/Hemp+Seeds%2c+One+of+the+Ways+to+Rebalance+and+Detox+Your+B ody-a01073882954
Milking your options-- Rice, hemp, cow, soy, almond or goat milk -- which one is better for you? (news 2009)
http://www.mnn.com/health/fitness-well-being/stories/milking-your-options
Canna Milk and more
(forum thread - 2010) (article 2010) (news - 2010) (news - 2010)
How Is Hemp Seed Milk Made?
http://www.ehow.com/about_6724476_hemp-seed-milk-made_.html
Form of medical marijuana won't get you high, but it's creating a buzz Juiced Marijuana Offered to Medical Users as Alternative to Smoking
http://www.drugfree.org/join-together/addiction/juiced-marijuana-offered-to
http://www.washingtonpost.com/wp-dyn/content/article/2010/05/31/AR2010053103231.html
A sip replaces a toke with new marijuana soda
(news 2011)
http://www.mnn.com/health/fitness-well-being/stories/a-sip-replaces-a-toke-with-new-marijuana-soda
FOODS - also see NUTRITION Cannabis Recipes (forum thread - 2004)

http://www.icmag.com/ic/showthread.php?t=7602&highlight=elixer
Alice B. Toklas brownies: the recipe!

http://www.straightdope.com/columns/read/880/alice-b-toklas-brownies-the-recipe
The Stoner's Cookbook Recipes from "Onlinepot"
(no date)
http://www.thestonerscookbook.com/
(no date) http://www.onlinepot.org/recipes.htm
433
Hemp Seed Recipes
(collection- no date) (news - no date) (news - no date)
http://www.manitobaharvest.com/recipes/
How To Make Canna Oil How To Make Cannabutter
http://www.medicalmarijuanami.com/how-to-make-cannaoil.htm
http://www.medicalmarijuanami.com/how-to-make-cannabutter.htm
Cannabis butter to spread across Europe Cannabutter In 7 Easy Steps!
(news - 2004)
http://www.globalhemp.com/News/2004/April/cannabis_butter.php
(forum thread- 2005) (news 2008)
Hemp Seeds, One of the Ways to Rebalance and Detox Your Body
http://www.thefreelibrary.com/Hemp+Seeds%2c+One+of+the+Ways+to+Rebalance+and+Detox+Your+B ody-a01073882954
IC Recipe Guide The CBC Recipes
(forum thread- 2008) (forum thread - 2009) (news 2010)
Cannabis Cooking Oil
http://www.thecannabischef.com/content/cannabis-cooking-oil
Recipes that can make some lives easier; Cannabis Barbeque Sauce
(news - 2010)
http://www.examiner.com/chef-about-town-in-seattle/recipes-that-can-make-some-lives-easier-cannabisbarbeque-sauce
BadKat's CannaPharm: Canna Caps, UV Reactive GLOWING Hash Candy, Canna 'Bombs' & more (forum post 2011)
http://forum.grasscity.com/incredible-edible-herb/742831-badkats-cannapharm-canna-caps-uv-reactiveglowing-hash-candy-canna-bombs-more.html
Anchovy red wine vinegarette with or without cannabis oil
(news 2011)
http://www.examiner.com/chef-about-town-in-seattle/recipes-that-make-lives-easier-anchovy-red-winevinegarette-with-or-wi
METHODS OF USE - INHALER Pharmacological evaluation of aerosolized cannabinoids in mice.

(abst 2000)
434
Physiochemical and pharmacological characterization of a Delta(9)-THC aerosol generated by a metered dose inhaler. (abst 2002)
http://www.ncbi.nlm.nih.gov/pubmed?term=thc%20metered%20dose%20inhaler
Patent 67130489 tetrahydrocannabinol (9 THC) solution metered dose inhalers and methods of use (full 2004) http://www.patentstorm.us/patents/6713048/fulltext.html US Patent Application 20050079136 - Aerosol formulations of delta tetrahydrocannabinol (full 2005)
US Patent Application 20100012118 - Medicament dosage for inhaler

(full 2010)
METHODS OF USE - INJECTION- DO NOT TRY! Collapse after intravenous injection of hashish. Effect of Intravenous Injection of Marihuana (full -1968) (abst - 1969)
http://jama.amaassn.org/cgi/content/abstract/210/4/724?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis& searchid=1&FIRSTINDEX=3840&resourcetype=HWCIT
The toxicity of intravenously used marihuana.

(abst - 1975)
Emotional response to intravenous delta9tetrahydrocannabinol during oral surgery. (abst 1976) http://www.ncbi.nlm.nih.gov/pubmed/1062533 Adverse Effects of Intravenous Cannabis Tea
(full - 1977)
Plasma delta-9-tetrahydrocannabinol concentrations and clinical effects after oral and intravenous administration and smoking (abst - 1980)
Intravenous marijuana syndrome.
(full -1986)
435
The safety of studies with intravenous (9)-tetrahydrocannabinol in humans, with case histories. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21845389
METHODS OF USE - NASAL SPRAYS Intranasal absorption of Delta(9)-tetrahydrocannabinol and WIN55,212-2 mesylate in rats. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17014999 Cannabidiol bioavailability after nasal and transdermal application: effect of permeation enhancers. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20545522 Bioavailability of -tetrahydrocannabinol following intranasal administration of a mucoadhesive gel spray delivery system in conscious rabbits. (abst 2011)
METHODS OF USE - OROMUCOSAL SPRAY also see Sativex Cannabis; Adverse Effects from an Oromucosal Spray.
http://www.nature.com/bdj/journal/v203/n6/full/bdj.2007.749.html
(full 2007)
METHODS OF USE RSO / RICK SIMPSONS OIL Run From the Cure Transcript (forum post - 2009)
https://www.greenpassion.org/index.php?/topic/14222-run-from-the-cure-transcript-of-thevideo/page__p__138476__hl__transcript__fromsearch__1#entry138476
The Illegal Herb that Fights Cancer
(news - 2011)
http://www.cannabisculture.com/v2/node/27122
Cannabis Science Provides Physicians Documentation That Confirms Successful Treatment of Skin Cancer (news/ info-mercial 2011)
Cannabis Oil Shrinks One Of The Worst Cancers (warning : graphic photos)
(news infomercial 2012)
http://cannabiscureuk.wordpress.com/2012/01/11/breaking-news-cannabis-science-inc-cannabis-oilshrinks-one-of-the-worst-cancers/
436
METHODS OF USE - SMOKING also see- SMOKED CANNABIS AS MEDICINE Rolling a Joint - Basic joint rolling tips Smoking Cannabis (news - no date) (article no date)
http://www.ukcia.org/culture/smoking.php#knife http://www.weedfarmer.com/joint_rolling/rolling/rolling.htm
Becoming a Marihuana User (full 1950)

http://joshpackard.files.wordpress.com/2008/09/becker-1953-marihuana-user.pdf
{delta}9-Transtetrahydrocannabinol and Natural Marihuana
(abst - 1973)
Effects of Marihuana on Man: Committee on Drugs
(full - 1975)
http://pediatrics.aappublications.org/cgi/reprint/56/1/134?maxtoshow=&hits=80&RESULTFORMAT=&fu lltext=marihuana&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
Herbal Intoxication: Psychoactive Effects From Herbal Cigarettes, Tea, and Capsules (full - 1976)

(abst 1980)
The seed and the soil: effect of dosage, personality and starting state on the response to delta 9 tetrahydrocannabinol in man. (full 1981)
The clinical pharmacology and dynamics of marihuana cigarette smoking
(abst - 1981)
Comparison of effects of marihuana cigarettes of three different potencies (full - 1982) http://www.nature.com/clpt/journal/v31/n5/pdf/clpt198286a.pdf Neurological and neuroradiological examination of chronic cannabis smokers. (abst 1983) http://www.ncbi.nlm.nih.gov/pubmed/6830182
437
Breathhold duration and response to marijuana smoke.
(abst - 1989)
http://www.ncbi.nlm.nih.gov/pubmed/2554344?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pub med_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA&linkpos=2&log$=relatedarticles&lo gdbfrom=pubmed
Marijuana Smoking: Factors That Influence the Bioavailability of Tetrahydrocannabinol (full - 1990) http://www.ukcia.org/research/FactorsThatInfluenceBioavailability.pdf Subjective and Behavioral Effects of Marijuana the Morning After Smoking. (abst - 1990)
http://medical-journals.healia.com/doc/2315429/Subjective-and-behavioral-effects-of-marijuana-themorning-after-smoking
Chronic Exposure to Delta 9-tetrahydrocannabinol Fails to Irreversibly Alter Brain Cannabinoid Receptors. (abst - 1991)
Response to marijuana as a function of potency and breathhold duration
(abst - 1991)
No increase in carcinogen-DNA adducts in the lungs of monkeys exposed chronically to marijuana smoke. (abst 1992) http://www.ncbi.nlm.nih.gov/pubmed/1488780 Marijuana smoking: effect of varying delta 9-tetrahydrocannabinol content and number of puffs. (abst - 1992)
Effects of water filtration on marijuana smoke: a literature review

http://www.ukcia.org/research/EffectsOfWaterFiltrationOnMarijuanaSmoke.php
(full - 1993)
Effects of delta 9-THC on marijuana smoking, dose choice, and verbal report of drug liking. (full - 1994) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1334408/?tool=pubmed Marijuana smoking: effects of varying puff volume and breathhold duration. (abst - 1995)
Effects of Varying Marijuana Potency on Deposition of Tar and D 9 -THC in the Lung During Smoking (full - 1997)
http://www.ukcia.org/research/EffectsOfVaryingMarijuanaPotency.pdf
Marijuana Water Pipe and Vaporizer Study

http://www.maps.org/news-letters/v06n3/06359mj1.html
(news - 2000)
438
A primer for patients use of medicinal marijuana
(full - 2001) (full 2003)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC81348/pdf/20010807s00037p329.pdf
Cannabis Use As Described by People with Multiple Sclerosis.

Concerning kif, a Cannabis sativa L. preparation smoked in the Rif mountains of northern Morocco. (full 2002)
http://www.goa-shoom.net/botanica/Merzouki_Kif%20and%20Cannabis_JE_2002.pdf
Comparison of smoked marijuana and oral Delta(9)-tetrahydrocannabinol in humans. (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/12457271 Cannabinoids and the immune system. Of men, mice and cells
(abst 2004) (abst 2005)
Bongs and Blunts: Notes from a Suburban Marijuana Subculture.
http://medical-journals.healia.com/doc/16537329/Bongs-and-blunts-notes-from-a-suburban-marijuanasubculture
Differential responses to cannabis potency: a typology of users based on self-reported consumption behaviour. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17689363 No Decrease in Pulmonary Function Associated with Long-Term Cannabis Smoking, Study Says (news - 2007) http://www.illinoisnorml.org/content/view/366/27/ Cannabis smoke condensate I: the effect of different preparation methods on tetrahydrocannabinol levels. (abst - 2008)
3.0 Dosing
(abst - 2009)
http://www.hc-sc.gc.ca/dhp-mps/marihuana/how-comment/medpract/infoprof/dosing-posologie-eng.php
A comparison of drug use and dependence between blunt smokers and other cannabis users (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19212929/abstract/A_comparison_of_drug_use_an d_dependence_between_blunt_smokers_and_other_cannabis_users_
Comparison of subjective, pharmacokinetic, and physiological effects of marijuana smoked as joints and blunts. (abst - 2009)
Smoked cannabis for chronic neuropathic pain: a randomized controlled trial (full 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950205/?tool=pmcentrez Cannabinoid receptor 1 binding activity and quantitative analysis of Cannabis sativa L. smoke and vapor. (full - 2010) http://www.jstage.jst.go.jp/article/cpb/58/2/58_201/_article
439
Disposition of smoked cannabis with high Delta(9)-tetrahydrocannabinol content: A kinetic model. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20450927/abstract/Disposition_of_smoked_cannab is_with_high_Delta_9__tetrahydrocannabinol_content:_A_kinetic_model_
Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20884951 Opioid antagonism enhances marijuana's effects in heavy marijuana smokers. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20490465/abstract/Opioid_antagonism_enhances_ marijuana%27s_effects_in_heavy_marijuana_smokers_
Cannabuttons and super cannabuttons
(forum post - 2010) (news - 2010) (full 2011)
Study Claims Cannabis Reduces Chronic Pain Effects of smoking cannabis on lung function
http://www.redorbit.com/news/health/1909943/study_claims_cannabis_reduces_chronic_pain/index.html
US Patent Application 20110073120 - Smoke and Odor Elimination Filters, Devices and Methods (full 2011) http://www.patentstorm.us/applications/20110073120/fulltext.html Quantification and comparison of marijuana smoking practices: blunts, joints, and pipes. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/20863627 Characterizing smoking topography of cannabis in heavy users.
(abst 2011)
Drug-Intake Methods and Social Identity: The Use of Marijuana in Blunts Among Southeast Asian Adolescents and Emerging Adults. (full 2011)

(news 2011)
Why doesnt marijuana cause cancer?
(news 2011) (abst 2012)
Patterns of blunt use among rural young adult african-american men.

Pot smoking not tied to middle-age mental decline
(news 2012)
440
METHODS OF USE - SUPPOSITORIES Rectal bioavailability of delta-9-tetrahydrocannabinol from various esters.

(abst 1991)
Rectal bioavailability of delta-9-tetrahydrocannabinol from the hemisuccinate ester in monkeys. (abst 1991) http://www.ncbi.nlm.nih.gov/pubmed/1664466 Bypassing the first-pass effect for the therapeutic use of cannabinoids.
(abst 1993)
US Patent 5389375 - Stable suppository formulations effecting bioavailability of 9 -thc (full - 1995) http://www.patentstorm.us/patents/5389375/fulltext.html US Patent 5508037 - Stable suppository formulations effecting bioavailability of 9 THC (full - 1996) http://www.patentstorm.us/patents/5508037/fulltext.html The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity: a pilot study with 2 patients. (abst - 1996)
METHODS OF USE - TINCTURES Tinctures - by Dr. Jay R. Cavanaugh, Ph.D.

http://www.letfreedomgrow.com/recipes/tincture.htm
(no date)
Extractum Cannabis Indicae (U. S. P.)Extract of Indian Cannabis. (1898)

http://www.henriettesherbal.com/eclectic/kings/cannabis-indi_extr.html
Extractum Cannabis Indicae Fluidum (U. S. P.)Fluid Extract of Indian Cannabis. (1898) http://www.henriettesherbal.com/eclectic/kings/cannabis-indi_extr1.html Tinctura Cannabis Indicae (U. S. P.)Tincture of Indian Cannabis. (1898)
http://www.henriettesherbal.com/eclectic/kings/cannabis-indi_tinc.html
Timeless tinctures
(forum - 2003)
Cannabis improves night vision: a case study of dark adaptometry and scotopic sensitivity in kif smokers of the Rif mountains of northern Morocco. (abst 2004)
http://science.iowamedicalmarijuana.org/pdfs/misc/Russo%20et%20al.%20Cannabis%20Night%20Vision %20JEP%202004.pdf
441
Pharmacokinetics and cannabinoid action using oral cannabis extract

(news 2005)
Unheated Cannabis sativa extracts and its major compound THC-acid have potential immuno-modulating properties not mediated by CB1 and CB2 receptor coupled pathways. (abst - 2006)
The Definitive Green Dragon (Revised, Updated, Combined) Glycerine-based Tincture Glysabis (forum thread - 2007)
(forum thread - 2006)
http://boards.cannabis.com/concentrates/82380-definitive-green-dragon-revised-updated-combined.html
http://www.icmag.com/ic/showthread.php?t=59924&highlight=Glysabis
Cannamist Tincture Recipe, and Instructions on How to Convert THCA Into THC (forum thread - 2008) http://www.greenpassion.org/showthread.php?t=4894 Tincture info from Aussie Ganja Faerie Marijuana Tincture (forum thread - 2009))
(article & video 2010) (forum thread- 2010)
http://patients4medicalmarijuana.wordpress.com/medical-use-of-cannabis-video/marijuana-tincture/
WildWill's Glycerin Tincture HOW-TO Extractum Cannabis (news - 2010)
http://forum.grasscity.com/incredible-edible-herb/655899-wildwills-glycerin-tincture-how.html
http://www.examiner.com/examiner/x-19678-Cannabis-Revolution-Examiner~y2010m4d4-ExtractumCannabis
METHODS OF USE - TOPICAL OINTMENTS In vitro experiment optimization for measuring tetrahydrocannabinol skin permeation. (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/12100860 Topical cannabinoid enhances topical morphine antinociception.
(abst - 2003)
442
Patent 6949582 - Method of relieving analgesia and reducing inflamation using a cannabinoid delivery topical liniment (full - 2005)
Homemade hemp salve
http://www.bushka.cz/archiv/mastEN.html
Want Nice Skin? Then Smoke Cannabis! (news 2007)

Marijuana Skin Cream? Glysabis
(news - 2007)
(forum thread - 2007) (forum thread - 2008)
http://www.icmag.com/ic/showthread.php?t=59924&highlight=Glysabis
WR's Cannabalm
http://www.420magazine.com/forums/cannabis-hemp-cream/144228-wr-s-cannabalm.html
Making HAO~Holy Annointing Oil~From Healing Hemp Oil~for Pain & Healing (forum thread - 2009)
http://www.greenpassion.org/f91/making-hao-holy-annointing-oil-healing-hemp-oil-pain-healing-17503/
Balm from canna roots
(forum thread - 2010) (article 2010)
Topical Cannabis Healing Salve
http://patients4medicalmarijuana.wordpress.com/2010/04/30/topical-cannabis-healing-salve/
US Patent Application 20110052694 - USE OF CANNABIDIOL PRODRUGS IN TOPICAL AND TRANSDERMAL ADMINISTRATION WITH MICRONEEDLES (full 2011) http://www.patentstorm.us/applications/20110052694/fulltext.html Cannabis Science Provides Physicians Documentation That Confirms Successful Treatment of Skin Cancer (news/ info-mercial 2011)
443
METHODS OF USE - TRANSDERMAL PATCH US Patent 6132762 - Transcutaneous application of marijuana

(full - 2000)
US Patent 6113940 - Cannabinoid patch and method for cannabis transdermal delivery (full 2000) http://www.patentstorm.us/patents/6113940/fulltext.html US Patent 6328992 - Cannabinoid patch and method for cannabis transdermal delivery (full - 2001) http://www.patentstorm.us/patents/6328992/fulltext.html Cannabidiol-transdermal delivery and anti-inflammatory effect in a murine model. (abst - 2003) http://www.ncbi.nlm.nih.gov/pubmed/14644587 In vitro/in vivo correlation studies for transdermal delta 8-THC development. (abst 2004) http://www.ncbi.nlm.nih.gov/pubmed/15067692 Human skin permeation of Delta8-tetrahydrocannabinol, cannabidiol and cannabinol. (abst - 2004) http://www.ncbi.nlm.nih.gov/pubmed/15025853 Enhancement of transdermal fentanyl and buprenorphine antinociception by transdermal delta9-tetrahydrocannabinol. (abst - 2005) http://www.ncbi.nlm.nih.gov/pubmed/16288738 Cannabidiol bioavailability after nasal and transdermal application: effect of permeation enhancers. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20545522 US Patent Application 20110052694 - USE OF CANNABIDIOL PRODRUGS IN TOPICAL AND TRANSDERMAL ADMINISTRATION WITH MICRONEEDLES (full 2011) http://www.patentstorm.us/applications/20110052694/fulltext.html Pot patch for your pooch developed in Seattle lab (news 2011)
http://www.king5.com/news/local/A-pot-patch-for-your-pooch-126363118.html
METHODS OF USE - VAPORIZERS ACCESSING 0.5 to 2.0 GRAMS CBD FRACTIONATING THE PHYTOCANNABINOIDS BY THEIR VAPORIZATION POINTS (article - no date ) http://forum.grasscity.com/medical-marijuana/610429-need-cbd.html Marijuana Water Pipe and Vaporizer Study
http://www.maps.org/news-letters/v06n3/06359mj1.html
(news - 2000)
NORML -MAPS Study Shows Vaporizers Reduce Toxins in Marijuana Smoke (news - 2001) http://www.canorml.org/healthfacts/vaporizerstudy1.html
444
Evaluation Of Volcano Vaporizer For The Efficient Emission Of THC, CBD, CBN And The Significant Reduction And/Or Elimination Of Polynuclear-Aromatic (PNA) Analytes Resultant Of Pyrolysis (full - 2003)
http://www.maps.org/mmj/vaporizerstudy4.15.03.pdf
Vaporizing cannabis is safer than smoking

http://www.cmaj.ca/cgi/eletters/169/3/222#405
(letter - 2003) (news - 2003)
Use of vaporizers reduces toxins from cannabis smoke
Cal NORML/MAPS study shows vaporizer can drastically reduce toxins in marijuana smoke (news - 2003) http://www.canorml.org/healthfacts/vaporizerstudy2.html Recommendation to Patients: "Dont smoke, Vaporize"
http://ccrmg.org/journal/03sum/vaporize.html
(news - 2003)
Cannabis Vaporizer Combines Efficient Delivery of THC with Effective Suppression of Pyrolytic Compounds (full - 2004) http://www.canorml.org/healthfacts/jcantgieringervapor.pdf Volcano is to Vaporizer As Porsche is to Automobile
http://ccrmg.org/journal/04spr/volcano.html
(news - 2004)
'Smokeless' medicinal pot has its advocates
(news - 2005)
http://www.sfgate.com/cgi-bin/article.cgi?file=/c/a/2005/06/20/MNG9GDBBLK1.DTL
US Patent 7088914 - Device, method and resistive element for vaporizing a medicament (full - 2006) http://www.patentstorm.us/patents/7088914/fulltext.html Evaluation of a vaporizing device (Volcano) for the pulmonary administration of tetrahydrocannabinol. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16637053 Decreased respiratory symptoms in cannabis users who vaporize.
(full - 2007)
Vaporization as a smokeless cannabis delivery system
(abst - 2007) (news - 2007) (news - 2007)
New Studies Destroy the Last Objection to Medical Marijuana

http://www.alternet.org/drugs/51277/
Vaporizers Could Remove Pitfalls of Smoking Medical Marijuana

http://www.drugfree.org/join-together/drugs/vaporizers-could-remove
Marijuana Vaporizer Provides Same Level Of THC, Fewer Toxins, Study Shows (news - 2007) http://www.sciencedaily.com/releases/2007/05/070515151145.htm
445
Smokeless Cannabis Delivery Device Efficient And Less Toxic

(news - 2007)
No Decrease in Pulmonary Function Associated with Long-Term Cannabis Smoking, Study Says (news - 2007) http://www.illinoisnorml.org/content/view/366/27/ Vaporized marijuana effect on CF. NOT smoking (forum post - 2007)
http://www.topix.com/forum/health/cystic-fibrosis/TBQ56B1VNGGAODTKA
Effect of intrapulmonary tetrahydrocannabinol administration in humans. (abst - 2008) http://marijuana.researchtoday.net/archive/5/8/1816.htm Cannabinoid Receptor 1 Binding Activity and Quantitative Analysis of Cannabis sativa L. Smoke and Vapor (full 2009) http://www.jstage.jst.go.jp/article/cpb/58/2/201/_pdf Cannabis smoke condensate III: The cannabinoid content of vaporised Cannabis sativa (abst - 2009) http://informahealthcare.com/doi/abs/10.3109/08958370902748559 Cannabinoid receptor 1 binding activity and quantitative analysis of Cannabis sativa L. smoke and vapor. (full - 2010) http://www.jstage.jst.go.jp/article/cpb/58/2/58_201/_article Pulmonary function in cannabis users: Support for a clinical trial of the vaporizer (full - 2010) http://www.lottoedge.com/Vaporizer%20in%20press.pdf
METHODS OF USE - VARIOUS Herbal Intoxication: Psychoactive Effects From Herbal Cigarettes, Tea, and Capsules (full - 1976)
Cannabinoids and appetite stimulation.

(abst 1994) (full 2002)

Human Cannabinoid Pharmacokinetics 2.0 Clinical Pharmacology (abst - 2009)
(full - 2007)
446
Dosage & Routes of Cannabis and Cannabinoid Administration
(article - 2010)
http://www.medicalcannabis.com/Dosage-and-Administration/dosage-a-administration
The medicinal use of cannabis and cannabinoids: an international survey on methods of intake. (abst 2011) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=482
MIGRAINE/ HEADACHE CANNABIS AND MARINOL IN THE TREATMENT OF MIGRAINE HEADACHE (abst - no date) http://www.druglibrary.org/schaffer/hemp/migrn2.htm MIGRAINE ASSOCIATED WITH MENSTRUATION (article - 1942) (on 3rd page)
http://jama.amaassn.org/cgi/reprint/120/4/324?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid= 1&FIRSTINDEX=320&resourcetype=HWCIT
Cannabinoids block release of serotonin from platelets induced by plasma from migraine patients (full - 1985) http://www.druglibrary.org/schaffer/hemp/medical/cannabin1.htm Chronic Migraine Headache: five cases successfully treated with Marinol and/or illicit cannabis. (abst- 1991) http://www.druglibrary.org/schaffer/hemp/migrn1.htm Cannabis for Migraine Treatment: Once and Future Treatment? An historical and scientific review (full - 1998)
http://www.druglibrary.org/crl/pain/Russo%2098%20Migraine_%20Pain.pdf
Hemp for Headache : An In-Depth Historical and Scientific Review of Cannabis in Migraine Treatment (full - 2001)
http://www.drugpolicy.org/docUploads/hemp_for_headache.pdf
Clinical Endocannabinoid Deficiency

(full - 2004)
Anandamide Is Able to Inhibit Trigeminal Neurons Using an in Vivo Model of Trigeminovascular-Mediated Nociception (full - 2004)
Cannabinoid (CB1) Receptor Activation Inhibits Trigeminovascular Neurons (full - 2006)

http://jpet.aspetjournals.org/content/320/1/64.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=c annabis&searchid=1&FIRSTINDEX=3680&resourcetype=HWCIT
447
Endocannabinoids in Chronic Migraine: CSF Findings Suggest a System Failure (full - 2006) http://www.nature.com/npp/journal/v32/n6/full/1301246a.html Dronabinol reduces signs and symptoms of idiopathic intracranial hypertension : a case report (abst + 1st page - 2006) http://www.liebertonline.com/doi/abs/10.1089/jop.2006.22.68 Biochemical Changes in Endocannabinoid System are Expressed in Platelets of Female but not Male Migraineurs (abst - 2006)
http://cep.sagepub.com/cgi/content/abstract/26/3/277?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabinoid&searchid=1&FIRSTINDEX=1200&resourcetype=HWCIT
Migraine may be related to under production of cannabinoids
(news - 2007)
Degradation of endocannabinoids in chronic migraine and medication overuse headache. (full - 2008)
http://science.iowamedicalmarijuana.org/pdfs/migraine/Cupini%20et%20al%202008%2018358734.pdf

(abst - 2009)
Inhaled Cannabis Aborts Cluster Headaches, Journal Reports

(news - 2009)
Alterations of the endocannabinoid system in an animal model of migraine: Evaluation in cerebral areas of rat ( abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19515121 Up in smoke: 'Cannabis gave me my life back' (anecdotal 2010)
http://www.independent.co.uk/life-style/health-and-families/features/up-in-smoke-cannabis-gave-me-mylife-back-2041640.html
The Use of Marijuana or Synthetic Cannabinoids for the Treatment of Headache (1st page 2011) http://onlinelibrary.wiley.com/doi/10.1111/j.1526-4610.2011.01848.x/abstract Interictal Type 1 Cannabinoid Receptor Binding is Increased in Female Migraine Patients. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22077199
MISCELLANEOUS STUFF Suppressive Effects of 2-thiouracil on Differentiation and Flowering in Cannabis Sativa. (abst 1960)
http://medical-journals.healia.com/doc/13713898/Suppressive-effects-of-2-thiouracil-on-differentiationand-flowering-in-Cannabis-sativa
448
Marijuana and Mutism
(abst - 1972)
Ingestion of Hashish Oil-filled Condoms.

(abst 1980)
Bias and the cannabis researcher. (abst 1981) http://www.ncbi.nlm.nih.gov/pubmed/6271821 Barba Jacob and the history of marihuana
(abst 1986) (full - 1987)
Retrieving impacted cannabis resin with ear drops.
Stability of Cannabinoids in Dried Samples of Cannabis Dating from Around 1896-1905. (abst 1990)
http://medical-journals.healia.com/doc/2314109/Stability-of-cannabinoids-in-dried-samples-of-cannabisdating-from-around-1896-1905
The Intangible Rewards from Crime: The Case of Domestic Marijuana Cultivation (abst - 1991)
http://cad.sagepub.com/content/37/4/506.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fulltext= marihuana&searchid=1&FIRSTINDEX=1840&resourcetype=HWCIT
Flashback Following Use of Cannabis--a Review
(abst 1991) (abst 1994)
Preference for High- Versus Low-potency Marijuana. Hemp Oil Fuels & How to Make Them
http://medical-journals.healia.com/doc/7862719/Preference-for-high-versus-low-potency-marijuana
(article 1997) (abst 1998) (abst 1998)
http://www.hempworld.com/Hemp-CyberFarm_com/htms/hemp-products/bio-diesel/bio-diesel.html
Providing medical marijuana: the importance of cannabis clubs.


Have I got brews for you... Hemp beer's here to stay.
(news 1998)
http://www.thefreelibrary.com/Have+I+got+brews+for+you...+Hemp+beer%27s+here+to+stay.a060746769
Thujone exhibits low affinity for cannabinoid receptors but fails to evoke cannabimimetic responses. (abst 1999) http://www.ncbi.nlm.nih.gov/pubmed/10080239
449
Development of a hemp (Cannabis sativa L.) simulation model. 2. The flowering response of two hemp cultivars to photoperiod (abst 2000)
http://cat.inist.fr/?aModele=afficheN&cpsidt=1463824
Distortion of Teatree Stems by Twine As a Means to Determine the Number of Years That the Stems Have Been Used to Support Cannabis Plants. (abst 2001)
http://medical-journals.healia.com/doc/11451066/Distortion-of-teatree-stems-by-twine-as-a-means-todetermine-the-number-of-years-that-the-stems-have-been-used-to-support-cannabis-plants
Cannabis-induced Koro in Americans.
(abst 2001) (abst 2000)
http://medical-journals.healia.com/doc/11784462/Cannabis-induced-Koro-in-Americans
Cannabinoid mimics in chocolate utilized as an argument in court

http://chocolate.org/chocdefence.html
Chronic Cannabis Use in the Compassionate Investigational New Drug Program: An Examination of Benefits and Adverse Effects of Legal Clinical Cannabis (full 2002) http://proxy.baremetal.com/cannabiscoalition.ca/chronic.pdf This Bud's Not For You (news 2002) (full 2003)
Patent 6503492 - Antiperspirant or deodorant compositions

Cannabis (marijuana) contamination of United States and foreign paper currency. (abst 2004) http://www.ncbi.nlm.nih.gov/pubmed/15516293 A biological oil adsorption filter. (abst 2004)
The Variation in Arrestees' Disclosure of Recent Drug Use Across Locations, Drugs, and Demographic Characteristics. (full 2005)
Medical marijuana and the Supreme Court.

http://www.nejm.org/doi/full/10.1056/NEJMp058165
(full 2005) (full 2005)
God forbid! Substance use among religious and non-religious youth.

Mother's milk and the muffin man: grassroots innovations in medical marijuana delivery systems. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/16537333 Cultivation of Cannabis sativa L. in northern Morocco.
(abst 2005)
450
Waterborne Lead Exposure Affects Brain Endocannabinoid Content in Male but Not Female Fathead Minnows (Pimephales Promelas). (abst 2005)
http://medical-journals.healia.com/doc/15527869/Waterborne-lead-exposure-affects-brainendocannabinoid-content-in-male-but-not-female-fathead-minnows-Pimephales-promelas
Ford And Deisel Never Intended Cars To Use Gasoline

http://www.rense.com/general67/FORD.HTM
(news 2005)
Marijauna Production in the United States
(full 2006)
http://www.drugscience.org/Archive/bcr2/MJCropReport_2006.pdf
Explicit and Implicit Effects of Anti-marijuana and Anti-tobacco Tv Advertisements. (abst 2006) http://www.sciencedirect.com/science/article/pii/S0306460306000955 ganja and Ayurveda (article - 2006)
http://tribes.tribe.net/adi_ayurveda/thread/8f985241-54c5-4969-b8cb-f2923532ff9c
THE RACE/ETHNICITY DISPARITY IN MISDEMEANOR MARIJUANA ARRESTS IN NEW YORK CITY (full - 2007)
Retail marijuana purchases in designer and commercial markets in New York City: sales units, weights, and prices per gram. (full 2007)
Do Medical Cannabis Laws Encourage Cannabis Use?

http://www.ijdp.org/article/S0955-3959%2806%2900211-8/abstract
(abst - 2007)
Detection method for the ability of hemp (Cannabis sativa L.) seed germination by the use of 2,3,5-triphenyl-2H-tetrazolium chloride (TTC) (full - 2008)
http://www.jstage.jst.go.jp/article/yakushi/128/11/128_1707/_article
Hemp Ethanol Saves the World (1) The Economics of Hemp Fuels Hemp Ethanol Saves the World (2) - The History of Hemp Fuels
http://hemp-ethanol.blogspot.com/2008/01/part-two-history-of-hemp-fuels.html
(article 2008)
http://hemp-ethanol.blogspot.com/2008/01/economics-history-and-politics-of-hemp.html
(article 2008) (article 2008)
Hemp Ethanol Saves the World (3) The Politics of Hemp Fuels
http://hemp-ethanol.blogspot.com/2008/01/part-three-politics-of-hemp-fuels.html
Assessment of Cannabinoids Content in Micropropagated Plants of Cannabis sativa and Their Comparison with Conventionally Propagated Plants and Mother Plant during Developmental Stages of Growth. (abst - 2009)
Hempcrete - Hemp Building Materials - Hemp For Houses

http://www.hemp.org/news/hempcrete-hemp-building-materials
(news 2009)
451
Medical Marijuana and the Law
(full - 2010)
http://content.nejm.org/cgi/content/full/362/16/1453?maxtoshow=&hits=80&RESULTFORMAT=&fulltex t=cannabinoid&searchid=1&FIRSTINDEX=2080&resourcetype=HWCIT
Cannabinoids Excite Circadian Clock Neurons
(full - 2010) (abst 2010) (abst 2010) (abst - 2010)
Tea catechins' affinity for human cannabinoid receptors.

The case for small-scale domestic cannabis cultivation.

The feasibility of converting Cannabis sativa L. oil into biodiesel

Hemp produces viable biodiesel, study finds

(news 2010) (abst 2010)
Colonic perforation: a lethal consequence of cannabis body packing.

High Frequency Plant Regeneration from Leaf Derived Callus of High 9Tetrahydrocannabinol Yielding Cannabis sativa L. (abst - 2010)
https://www.thieme-connect.de/DOI/DOI?10.1055/s-0030-1249773
Potency trends of 9-THC and other cannabinoids in confiscated cannabis preparations from 1993 to 2008 (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20487147/abstract/Potency_trends_of_%CE%949_ THC_and_other_cannabinoids_in_confiscated_cannabis_preparations_from_1993_to_2008_
Hemp could be key to zero-carbon houses

(news 2010)
Medicinal Marijuana Strains
(news 2010)
http://www.thefreelibrary.com/Medicinal+Marijuana+Strains-a01074139322
Scientists Find New Sources of Plant Cannabinoids Other than Medical Marijuana? (news 2010)
http://montanabiotech.wordpress.com/2011/03/26/scientists-find-new-sources-of-plant-cannabinoids-otherthan-medical-marijuana/
Cannabis electric car to be made in Canada
(news - 2010)
http://www.cbc.ca/technology/story/2010/08/23/cannabis-hemp-electric-car-kestrel-motive.html
Effect of various concentrations of Crocus sativus and Cannabis sativa extracts on luminescent biosensor Escherichia coli SM10 S1 (full 2011)
http://jjm.ajums.ac.ir/_jjm/documents/Issue%2012,%20S35-41MM.pdf
452
Bilateral testicular self-castration due to cannabis abuse: a case report

(warning- graphic pictures) http://www.jmedicalcasereports.com/content/5/1/404
(full 2011)
How well do international drug conventions protect public health? (abst- register free for full 2011)
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2811%2961423-2/fulltext
Study on spectral reflectance characteristics of hemp canopies

(abst 2011)
Factors determining yield and quality of illicit indoor cannabis (Cannabis spp.) production. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21737218 Bioconversion of industrial hemp to ethanol and methane: the benefits of steam pretreatment and co-production. (abst 2011)
Attempted ignition of petrol vapour by lit cigarettes and lit cannabis resin joints. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21605828 Molecular analysis of genetic fidelity in Cannabis sativa L. plants grown from synthetic (encapsulated) seeds following in vitro storage. (abst 2011)
Cadmium Tolerance and Bioaccumulation of 18 Hemp Accessions.

(abst 2011)
Reported value of cannabis seizures in Australian newspapers: are they accurate? (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21219493 High-performance sport, marijuana, and cannabimimetics.
(abst 2011) (abst 2011) (abst 2011)
Investigations into the Hypothesis of Transgenic Cannabis

What can we learn from the Dutch cannabis coffeeshop system?

"But my Doctor Recommended Pot": Medical Marijuana and the Patient-Physician Relationship. (abst 2011) http://marijuana.researchtoday.net/archive/8/10/4878.htm The Effect of Electrical Lighting Power and Irradiance on Indoor-Grown Cannabis Potency and Yield. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22211717 Medicinal Genomics Sequences the Cannabis Genome to Assemble the Largest Known Gene Collection of this Therapeutic Plant. (news 2011)
http://www.thefreelibrary.com/Medicinal+Genomics+Sequences+the+Cannabis+Genome+to+Assemble+th e...-a0264585240
453
Feasibility of Using Mycoherbicides to Control Illicit Drug Crops Is Uncertain (news 2011) http://www.sciencedaily.com/releases/2011/11/111130120116.htm Recycled Polyester, Organic Cotton or Hemp - Which is The Most Eco-Friendly Fiber? (news 2011)
http://www.mnn.com/communityblogs/nadia2/recycled-polyester-organic-cotton-or-hemp-which-is-themost-eco-friendly-fiber
125 Year Old Woman Claimed Smoking Cannabis Everyday Was Her Secret to Long Life (news 2011)
10 Questions To Ask Your Cannabis Scientist
(news- 2011)
http://www.freedomisgreen.com/10-questions-to-ask-your-cannabis-scientist/
Medical marijuana laws in 50 states: Investigating the relationship between state legalization of medical marijuana and marijuana use, abuse and dependence. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/22099393 Cannabis most widely used drug on Earth Chocolate & marijuana: chemical cousins (news 2012) (news 2011)
http://au.news.yahoo.com/latest/a/-/latest/12516855/cannabis-most-widely-used-drug-on-earth/
Jane-Ome, Marijuana iPad App Looks To Educate Users On Scientific Benefits (news /informercial 2012)
http://www.webpronews.com/jane-ome-marijuana-ipad-app-looks-to-educate-users-on-scientific-benefits2012-01
MORNING SICKNESS also see NAUSEA Hyperemesis Gravidarum and Clinical Cannabis: To Eat or Not to Eat? (abst - 2002) http://haworthpress.com/store/ArticleAbstract.asp?ID=18139 US Patent Application 20050165088 - Compositions comprising cannabinoids for treatment of nausea, vomiting, emesis, motion sickness or like conditions (full - 2005)
Marijuana effective against morning sickness: study

http://www.humanhemphealth.ca/The_Province_100605.html
(news - 2005)
454
Survey of medicinal cannabis use among childbearing women: patterns of its use in pregnancy and retroactive self-assessment of its efficacy against 'morning sickness'. (full 2006) http://safeaccess.ca/research/cannabis_nausea2006.pdf Breathe, Push, Puff? Pot Use and Pregnancy: A Review of the Literature
(news 2007)
(news - 2008)
Cannabinoid hyperemesis syndrome: an underreported entity causing nausea and vomiting of pregnancy. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21170540 Medical Marijuana: Can Pot Help Pregnant Women With Vomiting and Nausea? (article 2011)
http://patients4medicalmarijuana.wordpress.com/2011/01/13/pregnancy-and-medical-marijuana-can-pothelp-pregnant-women-with-vomiting-and-nausea/
MORTALITY RATES Annual Causes of Death in America (news - no date)

http://www.entheology.org/edoto/anmviewer.asp?a=3&z=5
INTERACTIONS OF 1-TETRAHYDROCANNABINOL WITH BARBITURATES AND METHAMPHETAMINE (abst - 1970)

Known drug-related deaths in the UK, 1990 Marijuana use and mortality. (full - 1997)
(list - 1990)
http://www.ukcia.org/research/DrugRelatedDeathsUK1990.php
Two hundred and thirteen cases of marijuana toxicoses in dogs.

http://www.ncbi.nlm.nih.gov/pubmed?term=Caroline%20W.%20Donaldson
(abst 2002)
Comparing cannabis with tobaccoagain Link between cannabis and mortality is still not established (full - 2003)
455
Marijuana Smoking Doesn't Lead to Higher Death Rate

http://ccrmg.org/journal/03sum/kaiser.html
(news - 2003)
How deadly is marijuana? Marijuana Smoking Doesn't Kill
(news - 2003) (news - 2003)
Illicit Drug Use in Young Adults and Subsequent Decline in General Health: The Coronary Artery Risk Development in Young Adults (CARDIA) Study (full - 2007)
Maternal use of cannabis and pregnancy outcome.

(abst 2002)
Marijuana Smoking Doesn't Kill
(news 2003) (full - 2009) (report - 2009)
Hashish Body Packing: A Case Report
Deaths from Marijuana v. 17 FDA-Approved Drugs No link found between cannabis and death
http://medicalmarijuana.procon.org/view.resource.php?resourceID=145
(news - 2009)
http://www.healthandage.com/no-link-found-between-cannabis-and-death
Information for Health Care Professionals (revised) - Overdose/Toxicity (Health Canada) (full - 2010)
http://www.hc-sc.gc.ca/dhp-mps/marihuana/how-comment/medpract/infoprof/index-eng.php#a9_0
An index of fatal toxicity for drugs of misuse.

(abst - 2010) (news - 2010)
Pregnant Women Smoking Pot Could Reduce Infant Mortality
MOTION SICKNESS US Patent Application 20050165088 - Compositions comprising cannabinoids for treatment of nausea, vomiting, emesis, motion sickness or like conditions (full - 2005) http://www.patentstorm.us/applications/20050165088/fulltext.html
456
The effects of cannabidiol and tetrahydrocannabinol on motion-induced emesis in Suncus murinus. (full 2008)

(full - 2010)
MRSA/ METHICILLIN-RESISTANT STAPHLOCOCCUS AUREUS HEMP AS A MEDICAMENT : Methods and results of the bacteriological experiments (full - 1955)
https://www.greenpassion.org/index.php?/topic/23448-methods-and-results-of-the-bacteriologicalexperiments/
Antibacterial preparation from hemp (Cannabis sativa)
(abst - 1958)
http://chemport.cas.org/cgibin/sdcgi?APP=ftslink&action=reflink&origin=ACS&version=1.0&coi=1%3ACAS%3A528%3ADyaG1c XpvVGiug%253D%253D&md5=36fcabac61432cf5e852c26c9bba3cd1
Hemp (Cannabis sativa)-an antibiotic drug. II. Methods and results of bacteriological investigations and preliminary clinical experiences (abst - 1958)
http://chemport.cas.org/cgibin/sdcgi?APP=ftslink&action=reflink&origin=ACS&version=1.0&coi=1%3ACAS%3A528%3ADyaG1c Xotl2guw%253D%253D&md5=a36c74726c1c02d8a52d1f297d624fc6

Doping the superbugs
(news - 2008) (news - 2008)
http://www.spectroscopynow.com/coi/cda/detail.cda?id=19457&type=Feature&chId=5&page=1
Chemicals in Marijuana May Fight MRSA Killing bacteria with cannabis
(news - 2008)
http://www.webmd.com/news/20080904/marijuana-chemicals-may-fight-mrsa
(news - 2008) (news - 2008)
http://arstechnica.com/journals/science.ars/2008/08/26/killing-bacteria-with-cannabis
Marijuana Ingredients Show Promise In Battling Superbugs

How pot may win the war against super-bacteria

http://healthcare.zdnet.com/?p=1324
(news - 2008)
457
A New MRSA Defense
(news - 2008) (news - 2008)
http://www.technologyreview.com/biomedicine/21366/?a=f
New medical uses found for marijuana
http://media.www.dailyfreepress.com/media/storage/paper87/news/2008/09/17/News/NewMedical.Uses.Found.For.Marijuana-3435667.shtml
Ganja Sacred Healer... Cannabinoids kill MRSA How cannabis could save your life (news - 2008)
(news - 2008)
http://2012.tribe.net/thread/64220726-9cea-459e-8c4f-b28133f7ced4
http://green.yahoo.com/blog/environmentalgraffiti/94/how-cannabis-could-save-yourlife.html;_ylt=A0S0znxCSWpK9SEAMQO4V8cX
Natural plant cannabinoids reduce multi-drug resistant infections

http://www.news-medical.net/?id=48757
(news - 2009) (news - 2009)
Cannabis Compounds Reduce Multi-Drug Resistant Infections
http://findarticles.com/p/articles/mi_m0EIN/is_20090423/ai_n31603664/?tag=content;col1
MULTIPLE SCLEROSIS/ MS The use of cannabinoids in MS: is it evidence based? (abst - no date) (abst - 1980)
http://www.ukcia.org/research/UseOfCannabinoidsInMSEvidenceBased.pdf
Marihuana as a therapeutic agent for muscle spasm or spasticity

Tetrahydrocannabinol for tremor in multiple sclerosis.
(abst - 1983) (abst - 1987) (abst - 1989)
Delta-9-THC in the treatment of spasticity associated with retinopathy.

Effect of cannabinoids on spasticity and ataxia in multiple sclerosis.

Nabilone in the treatment of multiple sclerosis
(abst - 1995)
The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity: a pilot study with 2 patients. (abst - 1996)
458
The perceived effects of smoked cannabis on patients with multiple sclerosis. (abst - 1997)

(abst 1999)
Analgesic effect of the cannabinoid analogue nabilone is not mediated by opioid receptors. (abst - 1999)
(full - 2000)

(full - 2000) (full - 2000)
Cannabinoids control spasticity and tremor in a multiple sclerosis model Cannabinoids reduce tremor in animal model of multiple sclerosis
http://www.ukcia.org/research/CannabinoidsControlSpasticityAndTremorInAMultipleSclerosisModel.php
(news - 2000)
http://www.cannabismed.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=12&search_pattern=Cannabinoids,reduce,tre mor,in,animal,model,of,multiple,sclerosis#2

(full - 2001)
The cannabinoids: an overview. Therapeutic implications in vomiting and nausea after cancer chemotherapy, in appetite promotion, in multiple sclerosis and in neuroprotection. (abst - 2001) http://www.ncbi.nlm.nih.gov/pubmed/11854768?dopt=Abstract Acute and chronic effects of cannabis based medicinal extract on refractory lower urinary tract dysfunction in patients with advanced multiple sclerosis early results (abst - 2001)
Chronic Cannabis Use in the Compassionate Investigational New Drug Program: An Examination of Benefits and Adverse Effects of Legal Clinical Cannabis (full 2002) http://proxy.baremetal.com/cannabiscoalition.ca/chronic.pdf Cannabinoids in the treatment of pain and spasticity in multiple sclerosis. (abst - 2002)

(abst - 2002)
459
Marijuana Helps MS Patients Alleviate Pain, Spasms
(news - 2002)
http://www.mult-sclerosis.org/news/Sep2002/MedMJForMSSpasmsAndPain.html
MS SUFFERER DEFENDS DRUG; CANNABIS HELPED ME WALK. (news - 2002)

http://www.thefreelibrary.com/MS+SUFFERER+DEFENDS+DRUG%3b+CANNABIS+HELPED+ME+ WALK.-a082609025
Cannabis Use As Described by People with Multiple Sclerosis.

(full 2003)
Therapeutic Action of Cannabinoids in a Murine Model of Multiple Sclerosis (full - 2003)

http://www.jneurosci.org/cgi/content/full/23/7/2511?maxtoshow=&hits=10&RESULTFORMAT=&fulltext =cannabis&andorexactfulltext=and&searchid=1&FIRSTINDEX=20&sortspec=relevance&resourcetype=H WCIT
(full - 2003)
http://brain.oxfordjournals.org/cgi/content/full/126/10/2191?ijkey=c7c6bfd158b85c98cb1a190d5ca261455 2989ba0
Whether whole plant Cannabis extracts can improve intractable neurogenic symptoms? (full - 2003) http://www.ukcia.org/research/WholePlantExtractsImproveNeurogenicSymptoms.pdf Immunoregulation of a viral model of multiple sclerosis using the synthetic cannabinoid R(+)WIN55,212 (full - 2003)

(full - 2003)
Randomised controlled trial of cannabis based medicinal extracts (CBME) in central neuropathic pain due to multiple sclerosis. (abst - 2003)
Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): multicentre randomised placebo-controlled trial. (abst - 2003)

(abst - 2003)
'How cannabis helped me'
(news/anecdotal - 2003) (news - 2003)
Cannabis helps symptoms of multiple sclerosis: study

http://www.cbc.ca/health/story/2003/11/07/ms_cannabis031107.html
460
Cannabis May Help Multiple Sclerosis Cannabis can help MS sufferers
(news - 2003)
http://www.webmd.com/multiple-sclerosis/news/20031106/cannabis-may-help-multiple-sclerosis
(news - 2003)
http://www.newscientist.com/article/dn4356-cannabis-can-help-ms-sufferers.html
Initial experiences with medicinal extracts of cannabis for chronic pain: Results from 34 N of 1 studies (full - 2004) http://www.ukcia.org/research/InitialExperiencesChronicPain.pdf Does the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double blind placebo controlled crossover trial (full - 2004)
http://www.bmj.com/cgi/content/full/329/7460/253
(full - 2004)
Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patients. (full - 2004)
http://www.ukcia.org/research/GenOrSpecEffectsOnMSSymptoms.pdf
Efficacy, safety and tolerability of an orally administered cannabis extract in the treatment of spasticity in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled, crossover study. (full - 2004)
http://www.ukcia.org/research/EfficacySafetyTolerabilityInMSSpasticityTreatment.pdf
An open-label pilot study of cannabis-based extracts for bladder dysfunction in advanced multiple sclerosis. (full - 2004)
http://www.ukcia.org/research/CBEForMSBladderDysfunction.pdf
Multiple Sclerosis Following Treatment with a Cannabinoid Receptor-1 Antagonist. (abst 2004)
http://medical-journals.healia.com/doc/15222701/Multiple-sclerosis-following-treatment-with-acannabinoid-receptor-1-antagonist
Are oral cannabinoids safe and effective in refractory neuropathic pain?

(abst - 2004)
Cannabis study encouraging for MS
(news - 2004) (news - 2004)
Cannabis Relieves Multiple Sclerosis Pain Cannabinoids for multiple sclerosis
http://www.webmd.com/multiple-sclerosis/news/20040715/cannabis-relieves-multiple-sclerosis-pain
(news - 2004) (news - 2004)
Cannabis truly helps multiple sclerosis sufferers
http://www.newscientist.com/article/dn6387-cannabis-truly-helps-multiple-sclerosis-sufferers.html
461
Therapy Insight: Bladder Dysfunction Associated With Multiple Sclerosis (full - 2005) http://www.medscape.com/viewarticle/515091 Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation (full - 2005) http://www.jneuroinflammation.com/content/2/1/29 Cannabinoids in multiple sclerosis (CAMS) study: safety and efficacy data for 12 months follow up (full - 2005)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1739436/pdf/v076p01664.pdf
Emerging properties of cannabinoid medicines in the management of multiple sclerosis (full - 2005) http://www.ukcia.org/research/ManagementOfMultipleSclerosis.pdf The synthetic cannabinoid R(+)WIN 55,212-2 inhibits the interleukin-1 signaling pathway in human astrocytes in a cannabinoid receptor-independent manner. (full 2005) http://www.jbc.org/content/280/43/35797.long Sativex: Fact Sheet (full - 2005)
http://www.bayer.ca/files/sativex_fs_fd_091289_e.pdf
(letter - 2005) (abst 2005)
http://www.bayer.ca/files/sativex_dhcpl_lapds_091289_e.pdf
Cannabinoids in multiple sclerosis -- therapeutically reasonable?


(abst 2005)
Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/16242629 Cannabis-based medicine in central pain in multiple sclerosis
http://www.neurology.org/cgi/content/abstract/65/6/812?etoc
(abst - 2005) (abst - 2005)
Cannabinoids and neuroprotection in CNS inflammatory disease.

Therapeutic action of cannabinoid on axonal injury induced by peroxynitrite (abst - 2005) http://www.ncbi.nlm.nih.gov/pubmed/16473327 Cannabis-based medicinal extract (Sativex) produced significant improvements in a subjective measure of spasticity which were maintained on long-term treatment with no evidence of tolerance. (abst - 2005)
462
Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis. (abst - 2005)
Marijuana derivatives may provide MS treatment
(news - 2005)
http://www.health.am/ab/more/marijuana_derivatives_may_provide_ms_treatment/
Medicinal marijuana use Experiences of people with multiple sclerosis (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1479734/?tool=pmcentrez Experimental autoimmune encephalomyelitis disrupts endocannabinoid-mediated neuroprotection (full - 2006)
Role of the Cannabinoid System in Pain Control and Therapeutic Implications for the Management of Acute and Chronic Pain Episodes (full - 2006)
Multiple sclerosis may disrupt endocannabinoid brain protection mechanism (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1458835/?tool=pmcentrez US Patent Application 20060167084 - Delta-9-THC compositions and methods for treating symptoms associated with multiple sclerosis (full - 2006 )
Sativex in patients with symptoms of spasticity due to multiple sclerosis (abst - 2006) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=169 Randomised controlled study of cannabis-based medicine (Sativex) in patients suffering from multiple sclerosis associated detrusor overactivity (abst - 2006)
The effect of cannabis on urge incontinence in patients with multiple sclerosis: a multicentre, randomised placebo-controlled trial (CAMS-LUTS). (abst - 2006)
Low dose treatment with the synthetic cannabinoid Nabilone significantly reduces spasticity-related pain : A double-blind placebo-controlled cross-over trial. (abst - 2006) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=200
463
(news - 2006)
The endocannabinoid system is dysregulated in multiple sclerosis and in experimental autoimmune encephalomyelitis (full - 2007)
Cannabinoid control of neuroinflammation related to multiple sclerosis (full - 2007) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2190016&tool=pmcentrez CB2 cannabinoid receptors as an emerging target for demyelinating diseases: from neuroimmune interactions to cell replacement strategies (full - 2007)
Cannabinoid CB1 and CB2 Receptors and Fatty Acid Amide Hydrolase Are Specific Markers of Plaque Cell Subtypes in Human Multiple Sclerosis (full - 2007)

Randomized controlled trial of cannabis-based medicine in spasticity caused by multiple sclerosis (full - 2007)
http://medicalcannabis.com/images/pdf09/indications/ms/collin_et_al_2007_sativex.pdf
Meta-analysis of cannabis based treatments for neuropathic and multiple sclerosis-related pain. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17257464 Oromucosal delta9-tetrahydrocannabinol/cannabidiol for neuropathic pain associated with multiple sclerosis: an uncontrolled, open-label, 2-year extension trial. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/18035205 The endocannabinoid system and neurogenesis in health and disease.
(abst - 2007)
464

(abst - 2007)
Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption (abst - 2007)
Cannabis-based medicine in spasticity caused by multiple sclerosis.
(abst - 2007)
http://www.unboundmedicine.com/medline/ebm/record/17355549/abstract/Randomized_controlled_trial_o f_cannabis_based_medicine_in_spasticity_caused_by_multiple_sclerosis
Cannabis based treatments for neuropathic and multiple sclerosis-related pain. (abst - 2007)
http://www.unboundmedicine.com/medline/ebm/record/17257464/abstract/Meta_analysis_of_cannabis_bas ed_treatments_for_neuropathic_and_multiple_sclerosis_related_pain
Symptomatic treatment of multiple sclerosis using cannabinoids: recent advances. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17868014 Cannabis' Potential Exciting Researchers in Treatment of ALS, Parkinson's Disease (news - 2007) http://www.illinoisnorml.org/index2.php?option=com_content&do_pdf=1&id=104 Cannabis could hold the key to ending multiple sclerosis misery
(news - 2007)
The CB2 Cannabinoid Receptor Controls Myeloid Progenitor Trafficking INVOLVEMENT IN THE PATHOGENESIS OF AN ANIMAL MODEL OF MULTIPLE SCLEROSIS (full - 2008) http://www.jbc.org/content/283/19/13320.long Cannabinoids in the management of difficult to treat pain (full - 2008)

(full - 2008) (full - 2008)

Cannabinoids in the management of spasticity associated with multiple sclerosis (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626929/?tool=pmcentrez
465
Current Status of Cannabis Treatment of Multiple Sclerosis with an Illustrative Case Presentation of a Patient with MS, Complex Vocal Tics, Paroxysmal Dystonia, and Marijuana Dependence Treated with Dronabinol. (full - 2008)
US Patent Application 20080181942 - Delta-9-THC compositions and methods for treating symptoms associated with multiple sclerosis (full 2008)
The endocannabinoid system and multiple sclerosis.

(abst - 2008)
Use Of Non-Psychoactive Cannabinoids In The Treatment Of Neurodegenerative Diseases. (news - 2008) http://www.sciencedaily.com/releases/2008/09/080916154721.htm Cannabis use in Spanish patients with multiple sclerosis (abst - 2008)
Cannabis May Halt Progression Of Multiple Sclerosis

(news - 2008) (news - 2008)
Can Cannabis Compounds Slow The Progression Of Multiple Sclerosis?

Cannabinoids as Therapeutic Agents for Ablating Neuroinflammatory Disease (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750822/?tool=pmcentrez Whole plant cannabis extracts in the treatment of spasticity in multiple sclerosis: a systematic review. (full - 2009)
(full - 2009) (full - 2009)
Cannabidiol: a promising drug for neurodegenerative disorders?

The Endocannabinoid Anandamide: From Immunomodulation to Neuroprotection. Implications for Multiple Sclerosis (abst - 2009)
466
A review of complementary and alternative medicine (CAM) by people with multiple sclerosis. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19222053/abstract/A_review_of_complementary_a nd_alternative_medicine__CAM__by_people_with_multiple_sclerosis_
Do cannabinoids reduce multiple sclerosis-related spasticity?
(abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19901724/full_citation/Do_cannabinoids_reduce_ multiple_sclerosis_related_spasticity

(abst - 2009)
14 of 15 MS patients show clinical improvement with cannabis consumption (news 2009)

http://www.examiner.com/disability-in-dallas/14-of-15-ms-patients-show-clinical-improvement-withcannabis-consumption
Clinical phase III study with the cannabis extract Cannador successful in multiple sclerosis (news - 2009)
Marijuana Eases Spasticity in MS Patients
(news 2009) (news - 2009) (news - 2009)
http://www.webmd.com/multiple-sclerosis/news/20091204/marijuana-eases-spasticity-in-ms-patients
Pot shows promise for reducing multiple sclerosis patients' symptoms Study Confirms That Cannabis Is Beneficial for Multiple Sclerosis
http://www.scientificamerican.com/blog/post.cfm?id=pot-shows-promise-for-reducing-mult-2009-12-02

(news - 2009)
Cannabis can reduce spasticity in MS patients
(news - 2009) (full - 2010)
http://www.news-medical.net/news/20091204/Cannabis-can-reduce-spasticity-in-MS-patients.aspx
Standardized Cannabis in Multiple Sclerosis: A Case Report

New approaches in the management of spasticity in multiple sclerosis patients: role of cannabinoids (full - 2010)
Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression. (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005548/?tool=pubmed Randomized controlled trial of Sativex to treat detrusor overactivity in multiple sclerosis. (abst 2010) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=314
467
Meta-analysis of the efficacy and safety of Sativex (nabiximols), on spasticity in people with multiple sclerosis (abst - 2010)
http://msj.sagepub.com/cgi/content/abstract/16/6/707?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabis&searchid=1&FIRSTINDEX=0&sortspec=date&resourcetype=HWCIT
The endocannabinoid system in the inflammatory and neurodegenerative processes of multiple sclerosis and of amyotrophic lateral sclerosis. (abst - 2010)
Julie Falco brings hope to Multiple Sclerosis patients. Cannabinoids manage pain and promote repair! (news - 2010)
http://www.examiner.com/x-19678-Cannabis-Revolution-Examiner~y2010m2d10-Julie-Falco-brings-hopeto-Multiple-Sclerosis-patients-Cannabinoids-manage-pain-and-promote-repair
The Multiplicity of Action of Cannabinoids: Implications for Treating Neurodegeneration. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20875047 Nature's (Legal) Cannabinoids (news - 2010) (news - 2010)
Marijuana and MS--an unfinished story.
http://www.thefreelibrary.com/Marijuana+and+MS--an+unfinished+story.-a0237205183
Weed Control Part 1: MS sufferer finds relief with medical marijuana (anecdotal/news - 2010)
http://www.thestarphoenix.com/opinion/sufferer+finds+relief+with+medical+marijuana/3198412/story.htm l
CANNABIDIOL INHIBITS PATHOGENIC T-CELLS, DECREASES SPINAL MICROGLIAL ACTIVATION AND AMELIORATES MULTIPLE SCLEROSIS-LIKE DISEASE IN C57BL/6 MICE. (full 2011)
Acute and chronic cannabinoid extracts administration affects motor function in a CREAE model of multiple sclerosis. (abst 2011)
Role of cannabinoids in multiple sclerosis

(abst 2011)
Inhibitory Effect of Standardized Cannabis sativa Extract and Its Ingredient Cannabidiol on Rat and Human Bladder Contractility. (abst 2011)
468
Identification of the synthetic cannabinoid R(+)WIN55,212-2 as a novel regulator of IFN regulatory factor 3 (IRF3) activation and IFN-{beta} expression: relevance to therapeutic effects in models of multiple sclerosis. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21245146/abstract/Identification_of_the_synthetic _cannabinoid_R_+_WIN55212_2_as_a_novel_regulator_of_IFN_regulatory_factor_3__IRF3__activation_ and_IFN_%7Bbeta%7D_expression:_relevance_to_therapeutic_effects_in_models_of_multiple_sclerosis_
A randomized, double-blind, placebo-controlled, parallel-group, enriched-design study of nabiximols* (Sativex() ), as add-on therapy, in subjects with refractory spasticity caused by multiple sclerosis. (abst 2011)
Treating pain in multiple sclerosis.
(abst 2011)
(news 2011)
MUSCULAR DYSTROPHY/ MD Muscular dystrophy in mice after chronic subcutaneous treatment with cannabinoids. (abst - 1977)
http://www.unboundmedicine.com/medline/ebm/record/903049/abstract/Muscular_dystrophy_in_mice_aft er_chronic_subcutaneous_treatment_with_cannabinoids_
For some chronically ill patients, pot succeeds where painkillers fail (news/ anecdotal - 2009)
http://www.nashuatelegraph.com/apps/pbcs.dll/article?AID=/20090211/NEWS01/302119895
Medical Marijuana use for Muscular Dystrophy
(news - 2009)
http://photos.nj.com/star-ledger/2009/09/medical_marijuana_use_for_musc_8.html
MUSCLE RELAXANT Effects of Cannabinoids on Caffeine Contractures in Slow and Fast Skeletal Muscle Fibers of the Frog (full - 2009)
469
Reposition of a dislocated shoulder under use of cannabis.
(abst 2009)
NABILONE / CESAMET - a synthetic THC, CB 1 & CB 2 agonist GENERIC NAME: NABILONE - ORAL (NAB-ih-lone) Brand Names : Cesamet (monograph - no date)
http://www.medicinenet.com/nabilone-oral/article.htm
Microbiological transformations of nabilone, a synthetic cannabinoid.

(full - 1979)
(full - 1980)
The efficacy and safety of nabilone (a synthetic cannabinoid) in the treatment of anxiety (abst - 1981)
A double-blind, controlled trial of nabilone vs. prochlorperazine for refractory emesis induced by cancer chemotherapy. (abst - 1982)
Anti-emetic efficacy and toxicity of nabilone, a synthetic cannabinoid, in lung cancer chemotherapy. (full - 1983)
Comparison of bronchial effects of nabilone and terbutaline in healthy and asthmatic subjects. (abst - 1983) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=43
470
Respiratory and cardiovascular depressant effects of nabilone, N-methyllevonantradol and delta 9-tetrahydrocannabinol in anesthetized cats. (abst - 1983)
Acute Effects of Natural and Synthetic Cannabis Compounds on Prolactin Levels in Human Males. (abst 1984) http://www.ncbi.nlm.nih.gov/pubmed/6320226 A cross-over comparison of nabilone and prochlorperazine for emesis induced by cancer chemotherapy. (abst - 1985)
Nabilone and metoclopramide in the treatment of nausea and vomiting due to cisplatinum: a double blind study. (abst - 1986)
Crossover comparison of the antiemetic efficacy of nabilone and alizapride in patients with nonseminomatous testicular cancer receiving cisplatin therapy. (abst - 1986)

(abst - 1986)

(abst - 1986)
A species comparison of the toxicity of nabilone, a new synthetic cannabinoid. (abst 1987) http://www.ncbi.nlm.nih.gov/pubmed/2888699 Species specificity in the metabolism of nabilone. Relationship between toxicity and metabolic routes. (abst - 1987) http://www.ncbi.nlm.nih.gov/pubmed/3037806 A double-blind randomised cross-over comparison of nabilone and metoclopramide in the control of radiation-induced nausea. (abst - 1987)
A randomized trial of oral nabilone and prochlorperazine compared to intravenous metoclopramide and dexamethasone in the treatment of nausea and vomiting induced by chemotherapy regimens containing cisplatin or cisplatin analogues. (abst 1988)
471
Effect of nabilone on nausea and vomiting after total abdominal hysterectomy (abst - 1994) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=137 Effect of nabilone on nausea and vomiting (letter - 1995)
Nabilone in the treatment of multiple sclerosis.
(abst - 1995)
Analgesic effect of the cannabinoid analogue nabilone is not mediated by opioid receptors. (excerpt - 1999)
Cannabis and cannabinoids: pharmacology and rationale for clinical use (abst 1999) http://pharmgkb.org/pmid/10575283 Different effects of nabilone and cannabidiol on binocular depth inversion in Man. (abst 2000) http://www.ncbi.nlm.nih.gov/pubmed/10837858 Delta(9)-tetrahydrocannabinol and synthetic cannabinoids prevent emesis produced by the cannabinoid CB(1) receptor antagonist/inverse agonist SR 141716A. (full 2001)
Cannabinoids reduce levodopa-induced dyskinesia in Parkinson's disease: a pilot study. (abst - 2001) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=54 Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat (full - 2002)

(abst - 2002) (abst - 2003)
Cannabinoid rotation in a young woman with chronic cystitis


(abst - 2003) (letter - 2006)
Nabilone Could Treat Chorea and Irritability in Huntingtons Disease

http://neuro.psychiatryonline.org/cgi/content/short/18/4/553?rss=1
472
Nabilone significantly reduces spasticity-related pain
(abst - 2006)
Synthetic cannabinomimetic nabilone on patients with chronic pain

(abst - 2006)
Low dose treatment with the synthetic cannabinoid Nabilone significantly reduces spasticity-related pain : A double-blind placebo-controlled cross-over trial. (abst - 2006)
Low dose treatment with the synthetic cannabinoid Nabilone significantly reduces spasticity-related pain : A double-blind placebo-controlled cross-over trial. (abst - 2006) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=200 The synthetic cannabinoid nabilone improves pain and symptom management in cancer patients (abst - 2006)
Nabilone improves pain and symptom management in cancer patients (abst - 2006) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=177 Synthetic cannabinomimetic nabilone on patients with chronic pain
(abst - 2006)
Cesamet (nabilone, Valeant Pharmaceuticals)
(news - 2006)
Cannabinoids in the treatment of chemotherapy-induced nausea and vomiting: beyond prevention of acute emesis. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17566383 Symptomatic treatment of multiple sclerosis using cannabinoids: recent advances. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17868014 Synthetic Cannabis for Fibromyalgia Pain? Nabilone relieves many advanced Ca symptoms (news - 2007) (news - 2007)
http://www.healthcentral.com/chronic-pain/c/5949/16104/fm-pain
473
(full - 2008)
Comparison of analgesic effects and patient tolerability of nabilone and dihydrocodeine for chronic neuropathic pain: randomised, crossover, double blind study. (full 2008)
Nabilone for the treatment of pain in fibromyalgia.

(abst - 2008)
Marijuana Derivative Called Effective in Fibromyalgia

http://www.medpagetoday.com/Rheumatology/Fibromyalgia/8377
(news - 2008) (news - 2008)
Marijuana-Based Drug Reduces Fibromyalgia Pain, Study Suggests

Cannabinoids, Endocannabinoids, and Related Analogs in Inflammation (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664885/?tool=pmcentrez The Effects of Nabilone on Sleep in Fibromyalgia: Results of a Randomized Controlled Trial. (full - 2009) http://www.anesthesia-analgesia.org/content/110/2/604.long Emerging strategies for exploiting cannabinoid receptor agonists as medicines. (full 2009) http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2008.00048.x/full A pilot study using nabilone for symptomatic treatment in Huntington's disease. (abst 2009)
http://www.unboundmedicine.com/medline/ebm/record/19845035/abstract/A_pilot_study_using_nabilone_ for_symptomatic_treatment_in_Huntington%27s_disease_
The use of a synthetic cannabinoid in the management of treatment-resistant nightmares in posttraumatic stress disorder (PTSD). (abst - 2009)
CESAMET CII (nabilone) Capsules For Oral Administration (Archived drug label - 2010)
http://dailymed.nlm.nih.gov/dailymed/archives/fdaDrugInfo.cfm?archiveid=16800
A randomized, double-blinded, crossover pilot study assessing the effect of nabilone on spasticity in persons with spinal cord injury. (abst - 2010)
474
An Open-Label Comparison of Nabilone and Gabapentin as Adjuvant Therapy or Monotherapy in the Management of Neuropathic Pain in Patients with Peripheral Neuropathy. (abst 2010)
NAIL-PATELLA SYNDROME Nail Patella Syndrome-Cannabinoids Relieve Symptoms

http://medicalmarijuana.com/medical-marijuana-treatments/NPS
(news no date)
Chronic Cannabis Use in the Compassionate Investigational New Drug Program: An Examination of Benefits and Adverse Effects of Legal Clinical Cannabis (full 2002) http://proxy.baremetal.com/cannabiscoalition.ca/chronic.pdf 'Trying to ease my suffering' (news 2008)
http://www.mlive.com/news/saginaw/index.ssf/2008/11/glaucoma_patient_turns_to_mari.html
NAUSEA - also see MORNING SICKNESS, MOTION SICKNESS, RADIATION-INDUCED NAUSEA Antiemetic effect of delta-9-tetrahydrocannabinol in patients receiving cancer chemotherapy. (full - 1975) http://www.ukcia.org/research/antiemetic.php Delta-9-Tetrahydrocannibinol as an Antiemetic in Cancer Patients Receiving High-Dose Methotrexate . A prospective, randomized evaluation (full - 1979)
http://www.medmjscience.org/Pages/science/chang.html
Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9tetrahydrocannabinol. (abst - 1979)

475
Antiemetic effect of tetrahydrocannabinol. Compared with placebo and prochlorperazine in chemotherapy-associated nausea and emesis (abst - 1980)
Antiemetics in patients receiving chemotherapy for cancer: a randomized comparison of delta-9-tetrahydrocannabinol and prochlorperazine. (abst - 1980)
Dose vs response of tetrahydroannabinol (THC) vs prochlorperazine as chemotherapy antiemetics. (abst - 1981)

Physiologic observations in a controlled clinical trial of the antiemetic effectiveness of 5, 10, and 15 mg of delta 9-tetrahydrocannabinol in cancer chemotherapy. Ophthalmologic implications. (abst - 1981)
Clinical experience with levonantradol hydrochloride in the prevention of cancer chemotherapy-induced nausea and vomiting. (abst 1981)
Comparative trial of the antiemetic effects of THC and haloperidol

(abst - 1981)
A double-blind, controlled trial of nabilone vs. prochlorperazine for refractory emesis induced by cancer chemotherapy. (abst - 1982)
Cannabis and cancer chemotherapy: a comparison of oral delta-9-THC and prochlorperazine. (abst 1982) http://www.ncbi.nlm.nih.gov/pubmed/6284334 A multi-institutional Phase III study of nabilone vs. placebo in chemotherapy-induced nausea and vomiting. (abst - 1982)
476
Anti-emetic efficacy and toxicity of nabilone, a synthetic cannabinoid, in lung cancer chemotherapy. (full -1983)
THC or Compazine for the cancer chemotherapy patient--the UCLA study. Part II: Patient drug preference. (abst - 1985)
A cross-over comparison of nabilone and prochlorperazine for emesis induced by cancer chemotherapy. (abst - 1985)
Nabilone and metoclopramide in the treatment of nausea and vomiting due to cisplatinum: a double blind study. (abst - 1986)

(abst - 1986)
Crossover comparison of the antiemetic efficacy of nabilone and alizapride in patients with nonseminomatous testicular cancer receiving cisplatin therapy. (abst - 1986)
Patent 5605928 - Antiemetic compositions

(full 1997)
A double-blind randomised cross-over comparison of nabilone and metoclopramide in the control of radiation-induced nausea. (abst - 1987)
Oral vs. Inhaled Cannabinoids for Nausea/Vomiting from Cancer Chemotherapy (full 1988) http://www.medmjscience.org/Pages/science/pierson.html
477
Efficacy of tetrahydrocannabinol in patients refractory to standard anti-emetic therapy (abst - 1988) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=31 A randomized trial of oral nabilone and prochlorperazine compared to intravenous metoclopramide and dexamethasone in the treatment of nausea and vomiting induced by chemotherapy regimens containing cisplatin or cisplatin analogues. (abst 1988)
Marijuana as antiemetic medicine: a survey of oncologists' experiences and attitudes. (abst - 1991) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=134 Effect of nabilone on nausea and vomiting after total abdominal hysterectomy. (abst - 1994) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=137 Effect of nabilone on nausea and vomiting (letter - 1995)
An efficient new cannabinoid antiemetic in pediatric oncology.

(abst - 1995)
Intractable nausea and vomiting due to gastrointestinal mucosal metastases relieved by tetrahydrocannabinol (dronabinol). (abst - 1997)

(full - 2001)
Delta(9)-tetrahydrocannabinol and synthetic cannabinoids prevent emesis produced by the cannabinoid CB(1) receptor antagonist/inverse agonist SR 141716A. (full 2001)
The cannabinoids: an overview. Therapeutic implications in vomiting and nausea after cancer chemotherapy, in appetite promotion, in multiple sclerosis and in neuroprotection. (abst - 2001) http://www.ncbi.nlm.nih.gov/pubmed/11854768?dopt=Abstract The cannabinoid agonist WIN55,212-2 suppresses opioid-induced emesis in ferrets. (abst - 2001) http://www.ncbi.nlm.nih.gov/pubmed/11388542 The cannabinoid CB1 receptor antagonist SR 141716A reverses the antiemetic and motor depressant actions of WIN 55, 212-2 (abst 2001) http://pharmgkb.org/pmid/11698062
478
Antiemetic efficacy of smoked marijuana: subjective and behavioral effects on nausea induced by syrup of ipecac (abst - 2001)
Hyperemesis Gravidarum and Clinical Cannabis: To Eat or Not to Eat? (abst - 2002) http://haworthpress.com/store/ArticleAbstract.asp?ID=18139 Delta9-tetrahydrocannabinol selectively acts on CB1 receptors in specific regions of dorsal vagal complex to inhibit emesis in ferrets. (full 2003)
Cannabinoids suppress synaptic input to neurones of the rat dorsal motor nucleus of the vagus nerve (full 2004) http://jp.physoc.org/content/559/3/923.full#sec-19 A comparative analysis of the potential of cannabinoids and ondansetron to suppress cisplatin-induced emesis in the Suncus murinus (house musk shrew). (abst 2004) http://www.ncbi.nlm.nih.gov/pubmed/14740147 US Patent Application 20050165088 - Compositions comprising cannabinoids for treatment of nausea, vomiting, emesis, motion sickness or like conditions (full - 2005) http://www.patentstorm.us/applications/20050165088/fulltext.html Delta-9-tetrahydrocannabinol and cannabidiol, but not ondansetron, interfere with conditioned retching reactions elicited by a lithium-paired context in Suncus murinus: An animal model of anticipatory nausea and vomiting. (abst 2006)
Prevention of nausea and vomiting following breast surgery.

(abst 2006)
Experience with the Synthetic Cannabinoid Nabilone in Chronic Noncancer Pain (abst 2006)
http://onlinelibrary.wiley.com/doi/10.1111/j.15264637.2006.00085.x/abstract;jsessionid=E64762ABC5DA541547D051CCC8EE2DFC.d03t01
Methods evaluating cannabinoid and endocannabinoid effects on gastrointestinal functions. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16506408 Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases. (abst - 2006)
479
US Patent Application 20070049645 - Anti-nausea and anti-vomiting activity of cannabidiol compounds (full 2007)

(abst - 2007)
Cannabinoids in the treatment of chemotherapy-induced nausea and vomiting: beyond prevention of acute emesis. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17566383 Efficacy of dronabinol alone and in combination with ondansetron versus ondansetron alone for delayed chemotherapy-induced nausea and vomiting. (abst - 2007)
Receptor mechanism and antiemetic activity of structurally-diverse cannabinoids against radiation-induced emesis in the least shrew. (abst - 2007)
http://www.unboundmedicine.com/medline/ebm/record/17362921/abstract/Receptor_mechanism_and_anti emetic_activity_of_structurally_diverse_cannabinoids_against_radiation_induced_emesis_in_the_least_shr ew
Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects (full 2008) http://gut.bmj.com/content/57/8/1140.full Medical marijuana: a surprising solution to severe morning sickness (news - 2008)
Mechanisms of Broad-Spectrum Antiemetic Efficacy of Cannabinoids against Chemotherapy-Induced Acute and Delayed Vomiting (full 2010)
Preliminary efficacy and safety of an oromucosal standardized cannabis extract in chemotherapy-induced nausea and vomiting (full - 2010)
http://www.unboundmedicine.com/medline/ebm/record/21039759/abstract/Preliminary_efficacy_and_safet y_of_an_oromucosal_standardized_cannabis_extract_in_chemotherapy_induced_nausea_and_vomiting_
The abuse potential of the synthetic cannabinoid nabilone.

(abst 2010)
(abst - 2010)

(abst - 2010)
480
Prescription Marijuana Without "Intoxicating" Effect in Research Stage
(news - 2010)
http://www.nbclosangeles.com/news/health/Scientists-Aim-to-Make-Marijuana-Perscription-Drug108736999.html
Medical Marijuana: Can Pot Help Pregnant Women With Vomiting and Nausea? (article 2011)
Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21243485 Cannabidiol, a Non-Psychotropic Component of Cannabis, Attenuates Vomiting and Nausea-like Behaviour via Indirect Agonism of 5-HT(1A) Somatodendritic: Autoreceptors in the Dorsal Raphe Nucleus. (abst 2011)
(abst 2011)
NEURONS/ BRAIN CELLS Cannabinoid Receptor Localization in Brain (full - 1990)

http://www.pnas.org/content/87/5/1932.full.pdf+html?maxtoshow=&hits=80&RESULTFORMAT=&fullte xt=cannabis&searchid=1&FIRSTINDEX=3760&resourcetype=HWCIT
Formation and inactivation of endogenous cannabinoid anandamide in central neurons. (letter 1994) http://www.nature.com/nature/journal/v372/n6507/abs/372686a0.html Anandamide amidohydrolase activity in rat brain microsomes. Identification and partial characterization. (full 1995) http://www.jbc.org/content/270/11/6030.long Genetic differences in delta 9-tetrahydrocannabinol-induced facilitation of brain stimulation reward as measured by a rate-frequency curve-shift electrical brain stimulation paradigm in three different rat strains. (abst 1996)
Cannabinoid Receptor Agonists Protect Cultured Rat Hippocampal Neurons from Excitotoxicity (full - 1998) http://molpharm.aspetjournals.org/content/54/3/459.full
481
Potent Effects of a Selective Cannabinoid Receptor Agonist on Some Guinea Pig Medial Vestibular Nucleus Neurons. (abst 1998)
http://medical-journals.healia.com/doc/9650841/Potent-effects-of-a-selective-cannabinoid-receptoragonist-on-some-guinea-pig-medial-vestibular-nucleus-neurons
Loss of Cannabinoid Receptor Binding and Messenger Rna Levels and Cannabinoid Agonist-stimulated [35s]guanylyl-5'o-(Thio)-triphosphate Binding in the Basal Ganglia of Aged Rats. (abst - 1998) http://www.ncbi.nlm.nih.gov/pubmed/9578396?dopt=Abstract Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain. (abst -1999)
Neuroprotective Antioxidants from Marijuana
(abst 2000)
Endocannabinoids in the central nervous system--an overview.

(abst - 2002)
Neurons on cannabinoids: dead or alive? Cannabis and the brain. (full - 2003)
(full - 2003)
Role of Endogenous Cannabinoids in Synaptic Signaling
(full - 2003)
Cannabinoid Modulation of Peripheral Autonomic and Sensory Neurotransmission. (abst - 2003)

http://medical-journals.healia.com/doc/12860468/Cannabinoid-modulation-of-peripheral-autonomic-andsensory-neurotransmission
(full - 2004) (full - 2004)
Defective adult neurogenesis in CB1 cannabinoid receptor knockout mice.

482
Marijuana-Like Chemicals in the Brain Calm Neurons

http://www.medpot.net/forums/index.php?showtopic=9686
(news - 2004)
http://www.jci.org/cgi/content/full/115/11/3104
Identification and functional characterization of brainstem cannabinoid CB2 receptors. (full - 2005) http://www.sciencemag.org/content/310/5746/329.full The endocannabinoid system drives neural progenitor proliferation.
(full 2005)
Sex differences in the cannabinoid modulation of an A-type K+ current in neurons of the mammalian hypothalamus. (full 2005) http://jn.physiology.org/content/94/4/2983.long High-dose cannabis stimulates growth of brain cells in rats (news 2005)
Marijuana Promotes Neuron Growth Marijuana May Spur New Brain Cells
(news - 2005) (forum/news - 2005)
http://english.ohmynews.com/articleview/article_view.asp?menu=c10400&no=253377&rel_no=1
Good News For The Medical Marijuana Movement: Pot Proliferates Brain Cells And Boosts Mood (news - 2005)
Marijuana May Grow Neurons in the Brain
(news - 2005) (news - 2005)
http://www.newscientist.com/article/dn8155-marijuana-might-cause-new-cell-growth-in-the-brain.html
Differential effects of cannabis extracts and pure plant cannabinoids on hippocampal neurones and glia. (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16997463?dopt=Abstract The synthetic cannabinoid HU210 induces spatial memory deficits and suppresses hippocampal firing rate in rats (full 2007)
483
CB2 cannabinoid receptors promote mouse neural stem cell proliferation.

(abst 2007)

(abst - 2007)
The CB2 Cannabinoid Receptor Controls Myeloid Progenitor Trafficking: INVOLVEMENT IN THE PATHOGENESIS OF AN ANIMAL MODEL OF MULTIPLE SCLEROSIS (full 2008)
http://www.jbc.org/content/283/19/13320.full?sid=a5db98db-ff96-4187-8790-57097bbe15c1#sec-3
Design Logic of a Cannabinoid Receptor Signaling Network That Triggers Neurite Outgrowth (full 2008)

(news - 2008)
Delta 9-tetrahydrocannabinol induces dopamine release in the human striatum. (full - 2009) http://www.nature.com/npp/journal/v34/n3/full/npp2008138a.html Cannabinoid agonist WIN-55,212-2 partially restores neurogenesis in the aged rat brain (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011092/?tool=pubmed Cannabinoids attenuate the effects of aging upon neuroinflammation and neurogenesis. (abst 2009) http://www.ncbi.nlm.nih.gov/pubmed/19385063 Endocannabinoid signaling in neurotoxicity and neuroprotection.
(abst - 2009)
Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania (abst 2009) http://jop.sagepub.com/content/25/2/274.abstract Cannabinoid receptors in brain: pharmacogenetics, neuropharmacology, neurotoxicology, and potential therapeutic applications. (abst - 2009)
New neuron production can be increased in the hippocampus of aged rats following cannabinoid treatment (abst 2009)
http://www.scribd.com/doc/49274316/smokeWeedErryDay
484
Sex difference in cell proliferation in developing rat amygdala mediated by endocannabinoids has implications for social behavior. (full 2010)
CB1 cannabinoid receptors increase neuronal precursor proliferation through AKT/glycogen synthase kinase-3beta/beta-catenin signaling. (full 2010)
Cannabidiol protects retinal neurons by preserving glutamine synthetase activity in diabetes. (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925907/?tool=pubmed Cannabinoids Excite Circadian Clock Neurons (full - 2010)
Endocannabinoids Prevent -Amyloid-mediated Lysosomal Destabilization in Cultured Neurons (abst 2010) http://www.jbc.org/content/285/49/38543.abstract Protective effects of the synthetic cannabinoids CP55,940 and JWH-015 on rat brain mitochondria upon paraquat exposure. (abst 2010)
Chronic Low Doses of a Cannabinoid Causes New Brain Cell Formation

http://cannabination.com/tag/nih/
(news - 2010)
Sex difference in cell proliferation in developing rat amygdala mediated by endocannabinoids has implications for social behavior (full 2011)
485
Cannabinoid receptor agonist protects cultured dopaminergic neurons from the death by the proteasomal dysfunction. (full 2011)
http://acbjournal.org/search.php?where=aview&id=184182&code=1049ACB&vmode=FULL
Endocannabinoid signaling in the amygdala: anatomy, synaptic signaling, behavior, and adaptations to stress. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21884761 The Dopamine and Cannabinoid Interaction in the Modulation of Emotions and Cognition: Assessing the Role of Cannabinoid CB1 Receptor in Neurons Expressing Dopamine D1 Receptors. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21887137 History of cannabis use is not associated with alterations in striatal dopamine D2/D3 receptor availability. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21890594/abstract/History_of_cannabis_use_is_no t_associated_with_alterations_in_striatal_dopamine_D2/D3_receptor_availability_
The G protein-coupled cannabinoid-1 (CB(1)) receptor of mammalian brain: Inhibition by phthalate esters in vitro. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21763743 -Tocopherol and -tocopheryl phosphate interact with the cannabinoid system in the rodent hippocampus. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21843633 Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions. (abst 2011) http://www.nature.com/neuro/journal/v14/n3/full/nn.2736.html Effects of synthetic cannabinoids on electroencephalogram power spectra in rats. (abst 2011)
(9)-THC and WIN55,212-2 affect brain tissue levels of excitatory amino acids in a phenotype-, compound-, dose-, and region-specific manner (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21645556/abstract/%CE%94_9__THC_and_WIN5 5212_2_affect_brain_tissue_levels_of_excitatory_amino_acids_in_a_phenotype__compound__dose__and _region_specific_manner_
Omega-3 PUFA Deficiency Abolishes Endocannabinoid-Linked Neuronal Functions (news - 2011) http://www.fatsoflife.com/article.php?nid=1&edition=this&id=1837&issueid=85
486
A Brain Wrought Without Omega-3
(news 2011)
NEUROPATHIC PAIN The perceived effects of smoked cannabis on patients with multiple sclerosis (abst - 1997) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=13 Meta-analysis of cannabis based treatments for neuropathic and multiple sclerosis-related pain. (abst - 1997)
http://www.unboundmedicine.com/medline/ebm/record/17257464/abstract/Meta_analysis_of_cannabis_bas ed_treatments_for_neuropathic_and_multiple_sclerosis_related_pain
The synthetic cannabinoid WIN55,212-2 attenuates hyperalgesia and allodynia in a rat model of neuropathic pain (full - 2001)
Whether whole plant Cannabis extracts can improve intractable neurogenic symptoms? (full - 2003) http://www.ukcia.org/research/WholePlantExtractsImproveNeurogenicSymptoms.pdf Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: Pain inhibition by receptors not present in the CNS (full - 2003)
Analgesic effect of the synthetic cannabinoid CT-3 on chronic neuropathic pain: a randomized controlled trial. (full - 2003)
http://jama.ama-assn.org/cgi/content/full/290/13/1757?ijkey=b86f3fe6d2018d53522ffca8e365fc2ff7aaf2fb
Randomised controlled trial of cannabis based medicinal extracts (CBME) in central neuropathic pain due to multiple sclerosis. (abst - 2003)
487
The effects of smoked cannabis in painful peripheral neuropathy and cancer pain refractory to opiods. (abst - 2003)
New Compound That Acts On Peripheral Receptors May Be Promising Treatment For Some Nerve Pain (news - 2003)
Initial experiences with medicinal extracts of cannabis for chronic pain: Results from 34 N of 1 studies (full - 2004) http://www.ukcia.org/research/InitialExperiencesChronicPain.pdf Efficacy of two cannabis based medicinal extracts for relief of central neuropathic pain from brachial plexus avulsion: results of a randomised controlled trial (full - 2004)
http://www.ukcia.org/research/CentralNeuropathicPainEfficacy.pdf

(abst - 2004)
Ajulemic acid (IP-751): Synthesis, proof of principle, toxicity studies, and clinical trials (full - 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751505/?tool=pubmed Smoked cannabis therapy for HIV-related painful peripheral neuropathy: results of a randomized, placebo-controlled clinical trial. (abst - 2005)
Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis (abst - 2005) http://www.neurology.org/cgi/content/abstract/65/6/812?etoc Effects of a Cannabinoid Agonist on Spinal Nociceptive Neurons in a Rodent Model of Neuropathic Pain (full - 2006) http://jn.physiology.org/cgi/content/full/96/6/2984 Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751298/?tool=pmcentrez CB1 receptor selective activation inhibits beta-amyloid-induced iNOS protein expression in C6 cells and subsequently blunts tau protein hyperphosphorylation in co-cultured neurons. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16837132 In MedPanel Summit, Leading Pain Experts Name Cannabinoids Among Most Promising Approaches to Treating Neuropathic Pain, Assert That Sociopolitical Climate Will Hamper Drug Approvals (news - 2006)
http://www.redorbit.com/news/health/545812/in_medpanel_summit_leading_pain_experts_name_cannabin oids_among_most/index.html?source=r_health
Endocannabinoid metabolism and uptake: novel targets for neuropathic and inflammatory pain (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190014/?tool=pubmed
488
The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3'carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice. (full - 2007) http://jpet.aspetjournals.org/content/322/1/236.long Cannabinoid CB2 receptors: a therapeutic target for the treatment of inflammatory and neuropathic pain (full - 2007)
Meta-analysis of cannabis based treatments for neuropathic and multiple sclerosis-related pain. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17257464 Sativex successfully treats neuropathic pain characterised by allodynia: A randomised, double-blind, placebo-controlled clinical trial (abst - 2007)
Oromucosal delta9-tetrahydrocannabinol/cannabidiol for neuropathic pain associated with multiple sclerosis: an uncontrolled, open-label, 2-year extension trial. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/18035205 Cannabis in painful HIV-associated sensory neuropathy: A randomized placebocontrolled trial. (abst - 2007)
Study Supports Medical Marijuana Use
(news - 2007)
http://www.drugfree.org/join-together/drugs/study-supports-medical
Smoked Cannabis Reduces Foot Pain Associated With HIV In Placebo Trial (news - 2007) http://www.sciencedaily.com/releases/2007/02/070212185335.htm Marijuana gives relief from chronic pain for AIDS sufferers
(news - 2007) (news - 2007) (news 2007)
Cannabis may be safe and effective for HIV-related neuropathic pain

http://www.aidsmap.com/en/news/E0578F66-B327-4504-836D-DEE790B87A0F.asp
Marijuana, Very Efficient in Cutting Off HIV Related Nerve Pain
http://news.softpedia.com/news/Marijuana-Very-Efficient-in-Cutting-off-HIV-Related-Nerve-Pain47003.shtml
Smoked Cannabis Proven Effective In Treating Neuropathic Pain

(news - 2007)
489
Crucial Role of CB2 Cannabinoid Receptor in the Regulation of Central Immune Responses during Neuropathic Pain (full - 2008)
Double Blind, Placebo Controlled Trial of Smoked Marijuana on Neuropathic Pain (full - 2008) http://www.cmcr.ucsd.edu/geninfo/Wilsey_2008.pdf Comparison of analgesic effects and patient tolerability of nabilone and dihydrocodeine for chronic neuropathic pain: randomised, crossover, double blind study. (full 2008)
A Randomized, Placebo Controlled Cross-Over Trial of Cannabis Cigarettes in Neuropathic Pain (full - 2008) http://www.cmcr.ucsd.edu/geninfo/Wilsey_2008.pdf Design and synthesis of a novel series of N-alkyl isatin acylhydrazone derivatives that act as selective cannabinoid receptor 2 agonists for the treatment of neuropathic pain. (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/18666769 Differential effects of repeated low dose treatment with the cannabinoid agonist WIN 55,212-2 in experimental models of bone cancer pain and neuropathic pain. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18611408 Antihyperalgesic effect of a Cannabis sativa extract in a rat model of neuropathic pain: mechanisms involved. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18618522 Medicinal Marijuana Effective For Neuropathic Pain In HIV, Study Finds (news - 2008)
Marijuana May Be Effective For Neuropathic Pain
(news - 2008)
Sustained antinociceptive effect of cannabinoid receptor agonist WIN 55,212-2 over time in rat model of neuropathic spinal cord injury pain (full - 2009)
Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19502530 Cannabinoids as pharmacotherapies for neuropathic pain: from the bench to the bedside. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19789075/abstract/Cannabinoids_as_pharmacother apies_for_neuropathic_pain:_from_the_bench_to_the_bedside_
490
Pharmacological characterization of a novel cannabinoid ligand, MDA19, for treatment of neuropathic pain. (full 2010) http://www.anesthesia-analgesia.org/content/111/1/99.long R-Flurbiprofen Reduces Neuropathic Pain in Rodents by Restoring Endogenous Cannabinoids (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869361/ Pharmacological Treatment of Painful HIV-Associated Sensory Neuropathy: A Systematic Review and Meta-Analysis of Randomised Controlled Trials (full 2010)
Smoked cannabis for chronic neuropathic pain: a randomized controlled trial (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950205/?tool=pmcentrez Misdiagnosed chronic pelvic pain: pudendal neuralgia responding to a novel use of palmitoylethanolamide. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20345619 An Open-Label Comparison of Nabilone and Gabapentin as Adjuvant Therapy or Monotherapy in the Management of Neuropathic Pain in Patients with Peripheral Neuropathy. (abst 2010)
Effect of dronabinol on central neuropathic pain after spinal cord injury: a pilot study. (abst 2010) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=313 Cannabinoid subtype-2 receptors modulate the antihyperalgesic effect of WIN 55,212-2 in rats with neuropathic spinal cord injury pain. (abst 2010)
Study Claims Cannabis Reduces Chronic Pain
(news - 2010) (news - 2010)
http://www.redorbit.com/news/health/1909943/study_claims_cannabis_reduces_chronic_pain/index.html
Cannabinoids inhibit and may prevent neuropathic pain in diabetes. Study: Smoking pot may ease chronic pain (news - 2010)
http://www.cnn.com/2010/HEALTH/08/30/health.pot.reduce.pain/
491
Cannabinoid Agonists Inhibit Neuropathic Pain Induced by Brachial Plexus Avulsion in Mice by Affecting Glial Cells and MAP Kinases. (full 2011)
Mutations in ABHD12 cause the neurodegenerative disease PHARC: An inborn error of endocannabinoid metabolism. (full 2011)
Cannabinoids for Treatment of Chronic Non-Cancer Pain; a Systematic Review of Randomized Trials. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21426373 Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21238581 Self-medication of a cannabinoid CB(2) agonist in an animal model of neuropathic pain. (abst 2011)
Activation of spinal and supraspinal cannabinoid-1 receptors leads to antinociception in a rat model of neuropathic spinal cord injury pain. (abst 2011)
Spinal cannabinoid CB2 receptors as a target for neuropathic pain: an investigation using chronic constriction injury. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22210507 Marijuana Extract Might Help Prevent Chemotherapy-Related Nerve Pain (news 2011) http://www.newswise.com/articles/view/580864/?sc=rsmn Cannabinoid 'Completely' Prevents Chemotherapy-Induced Neuropathy, Study Says (news 2011) http://www.norml.org/index.cfm?Group_ID=8710 Marijuana component may ease pain from chemo therapy drugs
(news 2011)
Prescribing Cannabis for Harm Reduction.
(full 2012)
http://www.harmreductionjournal.com/content/pdf/1477-7517-9-1.pdf
NEUROPROTECTANT Marijuana Protects Your Brain (news - no date) http://www.roninpub.com/art-mjbrain.html (abst - no date)
The use of cannabinoids in MS: is it evidence based?
http://www.ukcia.org/research/UseOfCannabinoidsInMSEvidenceBased.pdf
492
HU-211, a nonpsychotropic cannabinoid, produces short- and long-term neuroprotection after optic nerve axotomy. (abst 1996) http://www.ncbi.nlm.nih.gov/pubmed/8714863 Cannabidiol and delta 9THC are neuroprotective antioxidants (full - 1998)
Loss of Cannabinoid Receptor Binding and Messenger Rna Levels and Cannabinoid Agonist-stimulated [35s]guanylyl-5'o-(Thio)-triphosphate Binding in the Basal Ganglia of Aged Rats. (abst - 1998) http://www.ncbi.nlm.nih.gov/pubmed/9578396?dopt=Abstract Cannabinoid Antioxidant Protects Brain Cells -- Without the High
(news 1998)
Cannabinoids and Neuroprotection in Global and Focal Cerebral Ischemia and in Neuronal Cultures (full - 1999)
http://www.jneurosci.org/cgi/content/full/19/8/2987?maxtoshow=&hits=10&RESULTFORMAT=&fulltext =cannabis&andorexactfulltext=and&searchid=1&FIRSTINDEX=50&sortspec=relevance&resourcetype=H WCIT
Dexanabinol; a novel neuroprotective drug in experimental focal cerebral ischemia. (abst 1999) http://www.ncbi.nlm.nih.gov/pubmed/10202976 Neuroprotective Antioxidants from Marijuana (abst 2000)
Neuroprotection by Delta 9-Tetrahydrocannabinol, the Main Active Compound in Marijuana, against Ouabain-Induced In Vivo Excitotoxicity (full - 2001)
The cannabinoids: an overview. Therapeutic implications in vomiting and nausea after cancer chemotherapy, in appetite promotion, in multiple sclerosis and in neuroprotection. (abst - 2001) http://www.ncbi.nlm.nih.gov/pubmed/11854768?dopt=Abstract Cannabinoids and Brain Injury: Therapeutic Inplications
http://www.ukcia.org/research/CannabinoidsAndBrainInjury.pdf
(full - 2002)
Neurons on Cannabinoids: Dead or Alive?
(full - 2003)
http://www.ukcia.org/research/NeuronsDeadOrAlive.pdf
Neuroprotective Effect of()9-Tetrahydrocannabinol and Cannabidiol in N-Methyl-dAspartate-Induced Retinal Neurotoxicity (full 2003)
(news - 2003) http://www.idmu.co.uk/canncardio.htm
493
Cannabinoids As Neuroprotective Agents in Traumatic Brain Injury.
(abst - 2004)
http://www.benthamdirect.org/pages/content.php?CPD/2004/00000010/00000018/0007B.SGM
Protective effects of 9-tetrahydrocannabinol against N-methyl-D-aspartate-induced AF5 cell death (full - 2005)
Effects on cell viability. (abst 2005)
Cannabinoid-receptor 1 null mice are susceptible to neurofilament damage and caspase 3 activation. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/15953683 Marijuana might cause new cell growth in the brain
(news 2005)

Characterization of the neuroprotective effect of the cannabinoid agonist WIN-55212 in an in vitro model of hypoxic-ischemic brain damage in newborn rats. (abst 2006)
The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cells. (abst 2006)

494
Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: importance of antioxidant and cannabinoid receptor-independent properties. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17196181 The endocannabinoid system and neurogenesis in health and disease.
(abst - 2007)
Delta(9)-Tetrahydrocannabinol protects hippocampal neurons from excitotoxicity (abst - 2007)

http://www.unboundmedicine.com/medline/ebm/record/17140550/abstract/Delta_9__Tetrahydrocannabino l_protects_hippocampal_neurons_from_excitotoxicity
Cannabinoid CB1 receptor stimulation affords neuroprotection in MPTP-induced neurotoxicity by attenuating S100B up-regulation in vitro. (abst 2007)
Delta(9)-tetrahydrocannabinol (Delta(9)-THC) prevents cerebral infarction via hypothalamic-independent hypothermia. (abst - 2007)
http://www.unboundmedicine.com/medline/ebm/record/17289082/abstract/Delta_9__tetrahydrocannabinol __Delta_9__THC__prevents_cerebral_infarction_via_hypothalamic_independent_hypothermia
Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: importance of antioxidant and cannabinoid receptor-independent properties. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17196181 Neuroprotective and Intraocular Pressure-Lowering Effects of (-)DeltaTetrahydrocannabinol in a Rat Model of Glaucoma. (abst - 2007)
http://www.unboundmedicine.com/medline/ebm/record/17284931/abstract/Neuroprotective_and_Intraocul ar_Pressure_Lowering_Effects_of____Delta_Tetrahydrocannabinol_in_a_Rat_Model_of_Glaucoma
Increases in expression of 14-3-3 eta and 14-3-3 zeta transcripts during neuroprotection induced by Delta(9)-tetrahydrocannabinol in AF5 cells (abst - 2007)
http://www.unboundmedicine.com/medline/ebm/record/17455326/abstract/Increases_in_expression_of_14 _3_3_eta_and_14_3_3_zeta_transcripts_during_neuroprotection_induced_by_Delta_9__tetrahydrocannabi nol_in_AF5_cells
495
Endocannabinoids in the retina: From marijuana to neuroprotection. (full - 2008)

Endocannabinoid 2-Arachidonoylglycerol Protects Neurons by Limiting COX-2 Elevation (full 2008) http://www.jbc.org/content/283/33/22601.full Cannabidiol in medicine: a review of its therapeutic potential in CNS disorders (abst - 2008)

(abst - 2008)
Use Of Non-Psychoactive Cannabinoids In The Treatment Of Neurodegenerative Diseases. (news - 2008) http://www.sciencedaily.com/releases/2008/09/080916154721.htm Cannabidiol: a promising drug for neurodegenerative disorders?
(full - 2009)
Cannabidiol targets mitochondria to regulate intracellular Ca2+ levels.
(abst 2009)
http://www.unboundmedicine.com/medline/ebm/record/19228959/abstract/Cannabidiol_targets_mitochond ria_to_regulate_intracellular_Ca2+_levels_
Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania (abst 2009) http://jop.sagepub.com/content/25/2/274.abstract Neuroprotective potential of CB1 receptor agonists in an in vitro model of Huntington's disease. (full 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931573/?tool=pubmed Learning and memory performances in adolescent users of alcohol and marijuana: interactive effects. (full 2010)
THC Prevents MDMA Neurotoxicity in Mice.

(abst - 2010)
496
The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxicischemic brain damage in mice is mediated by CB(2) and adenosine receptors. (abst 2010)
Cannabinoids and Innate Immunity: Taking a Toll on Neuroinflammation (abst- with link to full 2011) http://www.tswj.com/2011/230786/abs/ Cannabinoid Receptor Type 1 Protects Nigrostriatal Dopaminergic Neurons against MPTP Neurotoxicity by Inhibiting Microglial Activation. (abst 2011)
Overexpression of CB2 cannabinoid receptors results in neuroprotection against behavioral and neurochemical alterations induced by intracaudate administration of 6hydroxydopamine. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/20980074 Pharmacological activation/inhibition of the cannabinoid system affects alcohol withdrawal-induced neuronal hypersensitivity to excitotoxic insults. (abst 2011)
Immunomodulatory properties of kappa opioids and synthetic cannabinoids in HIV-1 neuropathogenesis. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21850403 New metabolic pathway for controlling brain inflammation (news 2011)
Cannabinoid type 2 receptor activation downregulates stroke-induced classic and alternative brain macrophage/microglial activation concomitant to neuroprotection. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/22020035 Overexpression of CB2 cannabinoid receptors results in neuroprotection against behavioral and neurochemical alterations induced by intracaudate administration of 6hydroxydopamine. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/20980074
NIEMANN-PICK DISEASE Stimulation of Sphingomyelin Hydrolysis by Cannabidiol in Fibroblasts from a Niemannpick Patient. (abst - 1984)
http://medical-journals.healia.com/doc/6732800/Stimulation-of-sphingomyelin-hydrolysis-by-cannabidiolin-fibroblasts-from-a-Niemann-Pick-patient
497
NIGHT SWEATS The synthetic cannabinoid nabilone improves pain and symptom management in cancer patients (abst - 2006)
NUTRITION GENERAL - also see OMEGA3/ CB 1 CONNECTION Hemp and Flax Seeds and Oil in Modern Nutrition : An Overview (article no date) http://www.industrialhemp.net/pdf/Leson.HempAndFlax.pdf The Effect of Marijuana on Carbohydrate Metabolism. (abst 1976)
http://medical-journals.healia.com/doc/1251930/The-effect-of-marijuana-on-carbohydrate-metabolism
Beta-caryophyllene is a dietary cannabinoid Anti-inflammatory cannabinoids in diet Endocannabinoids and nutrition.
(full - 2008)
(full - 2008)
(full 2008) (news - 2008)
Anti-inflammatory compound from cannabis found in herbs

498
Exposure to a high-fat diet decreases sensitivity to 9-tetrahydrocannabinol-induced motor effects in female rats (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20850461 Scientists Find New Sources of Plant Cannabinoids Other than Medical Marijuana? (news 2010)
Poor Diet Impairs Cannabinoid Receptors
(news 2011)
NUTRITION HEMP SEED Hemp Protein = King of the Plant Kingdom Hemp Powder Vs. Hemp Oil Hemp Foods & Oils Primer (article - no date)
http://manitobaharvest.com/articles_studies/3804/Hemp-Protein-%3D-King-of-the-Plant-Kingdom.html
(article no date) (article - no date) (article - no date)
http://www.ehow.com/facts_5918149_hemp-powder-vs_-hemp-oil.html
http://manitobaharvest.com/articles_studies/3803/Hemp-Foods-%26amp%3B-Oils-Primer.html
Hemp Packs in Powerful Source of Preconception Nutrition
Hemp: Nature's Forgotten Superfood Cannabis Sativa Seed Pressings
(article - no date)
http://www.med-marijuana.com/index.htm
http://manitobaharvest.com/articles_studies/3802/Hemp%3A-Nature%27s-Forgotten-Superfood.html
(ad - no date)
The trypanocidal effect of Cannabis sativa constituents in experimental animal trypanosomiasis. (African Sleeping Sickness) (abst 1994)
HEMP AS A MEDICAMENT : Importance of hemp seeds in the tuberculosis therapy (Forum thread- full- 1955) (EDEZYME. recipe)
HEMP SEED: THE MOST NUTRITIONALLY COMPLETE FOOD SOURCE IN THE WORLD (1) (full - 1992) http://www.ratical.org/renewables/hempseed1.html HEMP SEED: THE MOST NUTRITIONALLY COMPLETE FOOD SOURCE IN THE WORLD (2) (full - 1992) http://www.ratical.org/renewables/hempseed2.html
499
Hempseed: Nature's Perfect Food?
(news - 1992)
http://www.marijuanalibrary.org/HT_Hempseed_0492.html
Marijuana-positive urine test results from consumption of hemp seeds in food products. (abst 1997) http://www.ncbi.nlm.nih.gov/pubmed/9323528 Hemp Foods and THC Levels: A Scientific Assessment 1 (full - 1999)
http://www.hempfood.com/thclimits1.html
Hemp Foods and THC Levels: A Scientific Assessment 2

http://www.hempfood.com/thclimits2a.html
(full - 1999)
Hemp and Health
(book excerpt - 1999) (news- 1999)
http://www.rexresearch.com/hhusb/hmphlth.htm#hhl3
A history of the Royal Grain
Evaluating the impact of hemp food consumption on workplace drug tests. (abst 2001) http://www.ncbi.nlm.nih.gov/pubmed/11765026 Nutritional Profile and Benefits of Hemp Seed, Nut, and Oil
http://www.drbronner.com/pdf/hempnutrition.pdf
(full - 2003)
Cannabis butter to spread across Europe
(news - 2004) (abst 2005) (abst 2006)
http://www.globalhemp.com/News/2004/April/cannabis_butter.php
The effect of feeding hemp seed meal to laying hens.

Alpha-linolenic acid content of commonly available nuts in Hangzhou.

Oily fish makes 'babies brainier'
(news - 2006) (hemp seed- at the very end)
9-Tetrahydrocannabinol Content of Commercially Available Hemp Products (full - 2008) https://secure.manitobaharvest.com/images/uploads/pages/File/thc_study_jat_2008.pdf Characterization, amino acid composition and in vitro digestibility of hemp (Cannabis) proteins (abst - 2008) http://cat.inist.fr/?aModele=afficheN&cpsidt=20168114 Initial study of Hemp seeds protein on antifatigue and the immunomodulation effects in mice (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/18589601 Cholesterol-induced stimulation of platelet aggregation is prevented by a hempseedenriched diet. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18418423
500
Initial study of Hemp seeds protein on antifatigue and the immunomodulation effects in mice (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/18589601 Hemp: A replacement for common food allergens? (news - 2009)
Curb Cravings With Hemp Seeds
(news - 2009) (full - 2010)
http://pr.cannazine.co.uk/200909231206/green/eco-news/curb-cravings-with-hemp-seeds.html
The cardiac and haemostatic effects of dietary hempseed.
http://www.nutritionandmetabolism.com/content/pdf/1743-7075-7-32.pdf
Influence of Feed Supplementation with Cannabis Sativa on Quality of Broilers Carcass (full - 2010) http://www.pvj.com.pk/pdf-files/30_1/34-38.pdf Information on Chia, Hemp & Flax (article 2010) (abst 2010)
http://www.ehow.com/facts_7460031_information-chia_-hemp-flax.html
Dietary intakes in a group of marihuana smoking patients

Evaluating the Quality of Protein from Hemp Seed (Cannabis sativa L.) Products Through the use of the Protein Digestibility-Corrected Amino Acid Score Method (abst - 2010) http://pubs.acs.org/doi/abs/10.1021/jf102636b The effects of hempseed meal intake and linoleic acid on Drosophila models of neurodegenerative diseases and hypercholesterolemia. (abst 2011)
Hemp Seeds are Full of Health
(news - 2010)
http://www.naturalnews.com/029729_hemp_seeds_health.html
Efficacy of a Chinese herbal proprietary medicine (Hemp Seed Pill) for functional constipation. (full 2011) http://www.nature.com/ajg/journal/v106/n1/pdf/ajg2010305a.pdf The effect of dietary hempseed on atherogenesis and contractile function in aortae from hypercholesterolemic rabbits. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21893466 Distinctive effects of plant protein sources on renal disease progression and associated cardiac hypertrophy in experimental kidney disease. (abst 2011)
Proteomic profiling of hempseed proteins from Cheungsam.

(abst - 2012)
501
NUTRITION HEMP SEED OIL Kings College Review of Nutritional Attributes of Cold Pressed Hemp Seed Oil (full no date) http://www.goodwebsite.co.uk/kingsreport.pdf Hemp Foods & Oils Primer (article - no date) (article - no date)
http://manitobaharvest.com/articles_studies/3803/Hemp-Foods-%26amp%3B-Oils-Primer.html
Hemp Oil vs Flax Oil. Which One is Right for Me?
http://manitobaharvest.com/articles_studies/3794/Hemp-Oil-vs-Flax-Oil.-Which-One-is-Right-forMe%3F.html
Hemp Powder Vs. Hemp Oil
(article no date) (article - no date)
http://www.ehow.com/facts_5918149_hemp-powder-vs_-hemp-oil.html
Hemp & GLA: Good Fat Burns Bad Fat
http://manitobaharvest.com/articles_studies/3813/Hemp-%26amp%3B-GLA%3A-Good-Fat-Burns-BadFat-.html
Uses for Hemp Oil
(article no date) (article - no date)
http://www.ehow.com/about_5340254_uses-hemp-oil.html
Hemp Seed Oil - Your source for essential fat Hemp: The Right Choice for Omega-6 Hemp Oil Vs. Flax Oil (article no date)
http://manitobaharvest.com/articles_studies/3810/Hemp-Seed-Oil---Your-source-for-essential-fat.html
(article - no date)
http://manitobaharvest.com/articles_studies/3814/Hemp%3A-The-Right-Choice-for-Omega-6-.html
http://www.ehow.com/facts_5949889_hemp-oil-vs_-flax-oil.html
Cannabis Sativa Seed Pressings Therapeutic Hemp Oil
(ad - no date) http://www.med-marijuana.com/index.htm
(news - 1993) http://www.ukcia.org/research/TherapeuticHempOil.php (full - 1996) (full - 1996) (full - 1999)
Hemp seed oil: A source of valuable essential fatty acids

http://www.hempfood.com/IHA/iha03101.html
Occurrence of "omega-3" stearidonic acid in hemp seed

Hemp Seed Oil : The Wonder Oil For the New Millennium Hemp and Health (book excerpt - 1999)
http://www.rexresearch.com/hhusb/hmphlth.htm#hhl4
502
Consumption and quantitation of delta9-tetrahydrocannabinol in commercially available hemp seed oil products. (abst 2000) http://www.ncbi.nlm.nih.gov/pubmed/11043660 Hemp Supplement Boosts Body AND Mind (anecdotal/news - 2001) (abst - 2002)
Characteristics of hemp (Cannabis sativa L.) seed oil
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T6R-44KW0MJ6&_user=10&_coverDate=01%2F31%2F2002&_alid=1224442428&_rdoc=729&_fmt=high&_orig=searc h&_cdi=5037&_sort=r&_st=13&_docanchor=&view=c&_ct=14348&_acct=C000050221&_version=1&_ urlVersion=0&_userid=10&md5=39826d98860a306a6242e1b6f6d60bd7
Nutritional Profile and Benefits of Hemp Seed, Nut, and Oil

http://www.drbronner.com/pdf/hempnutrition.pdf
(full - 2003)
Hemp-seed and olive oils: their stability against oxidation and use in O/W emulsions. (abst 2004) http://www.ncbi.nlm.nih.gov/pubmed/16130045 Hemp Oil (full - 2005) http://www.innvista.com/health/foods/hemp/hempoil.htm (abst - 2005)
Efficacy of dietary hempseed oil in patients with atopic dermatitis.

Study on the extraction process for cannabinoids in hemp seed oil by orthogonal design (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/16131037 Hemp-seed and olive oils: their stability against oxidation and use in O/W emulsions. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/16130045 How Hemp Seed Oil Can Help Your Arthritis Hemp Oil Compared to Flax Oil Hemp Seed Oil for Skin (news 2009)
(article 2010)
http://www.ehow.com/facts_7639247_hemp-oil-compared-flax-oil.html
(news 2010) (news - 2010)
Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions. (abst 2011) http://www.nature.com/neuro/journal/v14/n3/full/nn.2736.html Anchovy red wine vinegarette with or without cannabis oil (news 2011)
http://www.examiner.com/chef-about-town-in-seattle/recipes-that-make-lives-easier-anchovy-red-winevinegarette-with-or-wi
503
Hemp Oil Vs. Flax Oil
(news 2011) (news 2011)
http://www.livestrong.com/article/413750-hemp-oil-vs-flax-oil/
What Are the Benefits of Hemp Seed Oil?
http://www.ehow.com/facts_5796438_benefits-hemp-seed-oil_.html
O-1602 synthetic Cannabidiol analog, GPR 55 agonist A novel CB receptor GPR55 and its ligands are involved in regulation of gut movement in rodents. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21726355 The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55. (abst 2011)
A novel CB receptor GPR55 and its ligands are involved in regulation of gut movement in rodents. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21726355 The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21744421 A role for the putative cannabinoid receptor GPR55 in the islets of Langerhans. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21885477 The atypical cannabinoid O-1602 stimulates food intake and adiposity in rats. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/21981246
0-1966 - a synthetic, CB2 agonist Acute effects of a selective cannabinoid-2 receptor agonist on neuroinflammation in a murine model of traumatic brain injury (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21332427/abstract/Acute_effects_of_a_selective_c annabinoid_2_receptor_agonist_on_neuroinflammation_in_a_murine_model_of_traumatic_brain_injury_
Modulation of inflammatory responses by a cannabinoid-2-selective agonist after spinal cord injury. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21970496
504
OBESITY Hemp & GLA: Good Fat Burns Bad Fat (article - no date)
http://manitobaharvest.com/articles_studies/3813/Hemp-%26amp%3B-GLA%3A-Good-Fat-Burns-BadFat-.html
Effects of smoked marijuana on food intake and body weight of humans living in a residential laboratory. (abst - 1988)
Marijuana "Munchies" May Hold a Key to Obesity
(news - 2001)
http://www.webmd.com/news/20010411/marijuana-munchies-may-hold-key-to-obesity
Endocannabinoids and the regulation of body fat: the smoke is clearing

(full - 2003)
Short-term fasting and prolonged semistarvation have opposite effects on 2-AG levels in mouse brain. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12914975 CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity (full - 2004)
Activation of the Peripheral Endocannabinoid System in Human Obesity

(full - 2005)
Food for thought: endocannabinoid modulation of lipogenesis

(full - 2005)
505
Endocannabinoids and food intake: newborn suckling and appetite regulation in adulthood. (full - 2005) http://ebm.rsmjournals.com/cgi/content/full/230/4/225 Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity (full - 2005)
(abst - 2005)
Dysregulation of the Peripheral and Adipose Tissue Endocannabinoid System in Human Abdominal Obesity (full 2006)
Regulation, Function, and Dysregulation of Endocannabinoids in Models of Adipose and -Pancreatic Cells and in Obesity and Hyperglycemia (full - 2006)

(full - 2006)
(full - 2006)
The emerging role of the endocannabinoid system in endocrine regulation and energy balance. (full - 2006) http://edrv.endojournals.org/cgi/content/full/27/1/73 Human adipose tissue binds and metabolizes the endocannabinoids anandamide and 2arachidonoylglycerol. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16949718 Identification of Endocannabinoids and Related Compounds in Human Fat Cells (full - 2007) http://www.nature.com/oby/journal/v15/n4/full/oby2007100a.html The endogenous cannabinoid system: a new player in the brain-gut-adipose axis (full - 2007) http://www.cannabis-med.org/english/journal/en_2007_02_1.pdf GPR119, a novel G protein-coupled receptor target for the treatment of type 2 diabetes and obesity (full - 2008)
506
Activating Parabrachial Cannabinoid CB1 Receptors Selectively Stimulates Feeding of Palatable Foods in Rats (full - 2008)
Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects (full 2008) http://gut.bmj.com/content/57/8/1140.full Endocannabinoids and the Control of Energy Homeostasis
(full - 2008)
The Role of Adipocyte Insulin Resistance in the Pathogenesis of Obesity-Related Elevations in Endocannabinoids (full 2008)
http://diabetes.diabetesjournals.org/content/57/5/1262.full?sid=00769f3d-54ab-451b-b69e-4650931c5e25
Genetic Variations at the Endocannabinoid Type 1 Receptor Gene (CNR1) Are Associated with Obesity Phenotypes in Men (full - 2008)
http://jcem.endojournals.org/cgi/content/full/92/6/2382
Endocannabinoid dysregulation in the pancreas and adipose tissue of mice fed with a high-fat diet. (full - 2008) http://www.nature.com/oby/journal/v16/n3/full/oby2007106a.html The role of endocannabinoids in the regulation of gastric emptying: alterations in mice fed a high-fat diet. (full 2008)
(full 2008)
ENDOCANNABINOIDS AND THE NEUROCHEMISTRY OF GLUTTONY. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18638022 Dysregulation of the endocannabinoid system in obesity.
(abst 2008)
Cholesterol-induced stimulation of platelet aggregation is prevented by a hempseedenriched diet. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18418423 Synthetic and plant-derived cannabinoid receptor antagonists show hypophagic properties in fasted and non-fasted mice (full - 2009)
Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and energy processing induced by food deprivation and re-feeding. (full 2009)
507
Biomarkers of Endocannabinoid System Activation in Severe Obesity

(full - 2009)
Cannabinoids for clinicians: the rise and fall of the cannabinoid antagonists (full - 2009)
http://www.ejeonline.org/cgi/content/full/161/5/655?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid &searchid=1&FIRSTINDEX=160&resourcetype=HWCIT
Endocannabinoids and Their Receptors as Targets for Obesity Therapy

(full - 2009)

(abst - 2009) (abst 2009)
Anti-inflammatory effect of palmitoylethanolamide on human adipocytes.


(abst 2009)
Natural Pot-Like Compound Could Fight Obesity
(news - 2009)
http://www.scientificamerican.com/podcast/episode.cfm?id=natural-pot-like-compound-could-fig-09-12-29
Alterations in the hippocampal endocannabinoid system in diet-induced obese mice. (full 2010) http://www.jneurosci.org/content/30/18/6273.long Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients (full - 2010)

(full - 2010)
508
The Effects of Rimonabant on Brown Adipose Tissue in Rat: Implications for Energy Expenditure (full - 2010) http://www.nature.com/oby/journal/v17/n2/full/oby2008509a.html Cannabinoid receptor stimulation impairs mitochondrial biogenesis in mouse white adipose tissue, muscle, and liver: the role of eNOS, p38 MAPK, and AMPK pathways. (full 2010) http://diabetes.diabetesjournals.org/content/59/11/2826.long#sec-25 A common polymorphism in the cannabinoid receptor 1 (CNR1) gene is associated with antipsychotic-induced weight gain in Schizophrenia. (full 2010)
Modulation of Adipocyte Biology by 9-Tetrahydrocannabinol

http://www.nature.com/oby/journal/vaop/ncurrent/abs/oby2010100a.html
(abst - 2010)
Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood. (abst - 2010)
Cannabis Use and Obesity and Young Adults
( abst - 2010)
http://informahealthcare.com/doi/abs/10.3109/00952990.2010.500438
Krill oil significantly decreases 2-arachidonoylglycerol plasma levels in obese subjects. (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048484/?tool=pubmed Sweet taste and (AAT)12 repeat in the cannabinoid receptor gene in obese females (letter 2011) http://www.jstage.jst.go.jp/article/endocrj/58/4/323/_pdf Psychiatric adverse effects of rimonobant in adults with Prader Willi syndrome. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/20965292 The neutral cannabinoid CB receptor antagonist AM4113 regulates body weight through changes in energy intake in the rat. (abst 2011)
509
The role of central CB2 cannabinoid receptors on food intake in neonatal chicks. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21927979 Cannabidiol decreases body weight gain in rats: Involvement of CB2 receptors. (abst - 2011) http://marijuana.researchtoday.net/archive/8/1/3517.htm Obesity and Cannabis Use: Results From 2 Representative National Surveys (abst 2011)
http://aje.oxfordjournals.org/content/early/2011/08/24/aje.kwr200.abstract?sid=18de840f-92a2-40d2-b1542e236ba97020
Frequency Of Marijuana Use Associated With Lower Prevalence Of Obesity, Study Says (news 2011) http://www.norml.org/index.cfm?Group_ID=8670 Smoking marijuana not linked to obesity: study
(news 2011)
Dietary conditions and highly palatable food access alter rat cannabinoid receptor expression and binding density. (abst 2012)
The atypical cannabinoid O-1602 stimulates food intake and adiposity in rats. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/21981246
OBSESSIVE COMPULSIVE DISORDER Inhibition of fatty-acid amide hydrolase accelerates acquisition and extinction rates in a spatial memory task. (full 2007) http://www.nature.com/npp/journal/v32/n5/pdf/1301224a.pdf Improvement in Refractory Obsessive Compulsive Disorder With Dronabinol (letter - 2008) http://ajp.psychiatryonline.org/cgi/content/full/165/4/536 Science: THC effective in obsessive compulsive disorder according to case reports (news - 2008)
Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20695034 Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), (9)-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessivecompulsive behaviour. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21796370
510
OMEGA-3/ CB1 CONNECTION (without Omega 3, new CB1 receptors are made imperfectly)
also see NUTRITION HEMP SEED OIL, CBR- CB1 receptors
(article - no date)
Omega-3 and Omega-6 Essential fatty Acids (EFA) (infomercial/ad no date)

http://www.advance-health.com/efa.html
Occurrence of "omega-3" stearidonic acid in hemp seed

(full - 1996)
Effect of maternal under-nutrition on pup body weight and hypothalamic endocannabinoid levels. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12678501 Oily fish makes 'babies brainier' (news - 2006) (hemp seed- at the end)
Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood. (abst 2010)
Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines. (full 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930808/?tool=pubmed Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions. (abst 2011) http://www.nature.com/neuro/journal/v14/n3/full/nn.2736.html Fish oil promotes survival and protects against cognitive decline in severely undernourished mice by normalizing satiety signals. (abst 2011)
511
Omega-3 PUFA Deficiency Abolishes Endocannabinoid-Linked Neuronal Functions (news - 2011) http://www.fatsoflife.com/article.php?nid=1&edition=this&id=1837&issueid=85 Omega-3 deficiency disrupts cannibinoid receptor function in brain (news 2011)
A Brain Wrought Without Omega-3 Poor Diet Impairs Cannabinoid Receptors
(news 2011) (news 2011)
Cannabinoid Receptor Function is Altered by Nutrionally Deficient Diet (news 2012)

http://www.examiner.com/medical-marijuana-in-philadelphia/cannabinoid-receptor-function-is-altered-bynutrionally-deficient-diet
ORGAN TRANSPLANTS Fatal aspergillosis associated with smoking contaminated marijuana, in a marrow transplant recipient. (full - 1988) http://chestjournal.chestpubs.org/content/94/2/432.long Successfully treated invasive pulmonary aspergillosis associated with smoking marijuana in a renal transplant recipient. (abst - 1996) http://www.ncbi.nlm.nih.gov/pubmed/8685958 Exogenous lipid pneumonia related to smoking weed oil following cadaveric renal transplantation (abst, click for full- 2000) http://www.ncbi.nlm.nih.gov/sites/pubmed Marinol Death Sentence: Oregon Man Denied Liver Transplant Because of Prescription - He's Not the Only One (news 2003)
http://stopthedrugwar.org/chronicle-old/299/notransplant.shtml
The debate about marijuana usage in transplant candidates: recent medical evidence on marijuana health effects. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18685302 Medical Marijuana Users Denied Organ Transplants (news 2008) (news 2008)
http://blogs.wsj.com/health/2008/05/19/medical-marijuana-users-denied-organ-transplants/
Is medical-marijuana use reason to deny someone an organ transplant?

http://seattletimes.nwsource.com/html/health/2004389825_liver03m.html
512
Should Hepatitis C Patients Who Smoke Marijuana Be Eligible For Liver Transplants? (news - 2008) http://www.sciencedaily.com/releases/2008/10/081022211032.htm Marijuana Use in Potential Liver Transplant Candidates. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19067667/abstract/Marijuana_Use_in_Potential_Li ver_Transplant_Candidates_
Woman Dies After Being Denied Organ Transplant
(news 2009) (full 2010) (abst 2010)
http://ssdp.org/news/blog/woman-dies-after-being-denied-organ-transplant
Do cannabinoids have a therapeutic role in transplantation

Denial of hepatic transplantation on the basis of smoking: is it ethical?

Oregon hospitals denying life saving organ transplants to legal medical marijuana patients (news - 2010)
http://www.huffingtonpost.com/russ-belville/oregon-hospitals-denying_b_575965.html
Health Tragedy: Patients Denied Life-Saving Transplants for Their "Abuse of Illicit Substances" (news 2010)
http://www.alternet.org/health/145432/health_tragedy%3A_patients_denied_lifesaving_transplants_for_their_%22abuse_of_illicit_substances%22
Targeting cannabinoid receptors as a novel approach in the treatment of graft-versus-host disease: Evidence from an experimental murine model. (full 2011)
http://jpet.aspetjournals.org/content/early/2011/06/14/jpet.111.182717.long
Cannabinoid receptor 2 and its agonists mediate hematopoiesis and hematopoietic stem and progenitor cell mobilization. (abst 2011)
The Denial of Organ Transplants to Medical Marijuana Patients
(news 2011)
http://www.huffingtonpost.com/russ-belville/the-denial-of-organ-trans_b_435348.html
Cancer Patient Taken Off Of Liver Transplant List Because Of Medical Marijuana Use (news 2011) http://americansforsafeaccess.org/article.php?id=6986 Cedars-Sinai Denying Transplant To Medical Marijuana Patient With Inoperable Liver Cancer (news 2011)
http://www.cannabisculture.com/v2/content/2011/11/17/Cedars-Sinai-Denying-Transplant-MedicalMarijuana-Patient-Inoperable-Liver-Cancer
513
OSTEOPOROSIS/ BONES Cannabinoid receptor type 2 gene is associated with human osteoporosis (full - 2005)
http://hmg.oxfordjournals.org/cgi/content/full/14/22/3389?maxtoshow=&hits=80&RESULTFORMAT=&f ulltext=cannabinoid&searchid=1&FIRSTINDEX=400&resourcetype=HWCIT
Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptors (full - 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1430341/?tool=pmcentrez Peripheral cannabinoid receptor, CB2, regulates bone mass
(full - 2006)
Involvement of Neuronal Cannabinoid Receptor CB1 in Regulation of Bone Mass and Bone Remodeling (full - 2006)
Researchers from the Hebrew University Discover New Drug for Osteoporosis (news 2006)
http://news.softpedia.com/news/Researchers-From-the-Hebrew-University-Discover-New-Drug-forOsteoporosis-15808.shtml
New hope for osteoporosis sufferers
(news - 2006)
Prototype drug to prevent osteoporosis based on cannabinoids found in the body (news - 2006) http://www.news-medical.net/?id=15220 Hebrew U. Researchers Find Cannabis Can Strengthen Bones
http://www.israelnationalnews.com/News/News.aspx/96146
(news - 2006)
Scientists Develop Prototype Drug To Prevent Osteoporosis Based On Cannabinoids Produced By Body (news - 2006)
New Weapon In Battle Against Osteoporosis

(news - 2006) (news - 2006)
Activation of CB2 receptor attenuates bone loss in osteoporosis Cannabis-like compound prevents bone loss (news - 2006)
http://www.thehempire.com/index.php/cannabis/news/cannabis_like_compound_prevents_bone_loss
Regulation of skeletal remodeling by the endocannabinoid system.

(abst - 2007)
514
Cannabinoids stimulate fibroblastic colony formation by bone marrow cells indirectly via CB2 receptors. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17205329 Cannabinoid receptors and the regulation of bone mass (full - 2008)
The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling. (full - 2008) http://www.fasebj.org/cgi/content/full/22/1/285 Role of cannabinoid receptors in bone disorders: alternatives for treatment (abst - 2008)
Ajulemic acid, a nonpsychoactive cannabinoid acid, suppresses osteoclastogenesis in mononuclear precursor cells and induces apoptosis in mature osteoclast-like cells. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/17786950 The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo (full - 2009)
The influence of cannabinoid CB2 receptor in adult rat mesenchymal stem cell viability (abst 2009)
http://www.physoc.org/custom2/publications/proceedings/archive/article.asp?ID=Proc%20Physiol%20Soc %2015PC171
Cannabidiol decreases bone resorption by inhibiting RANK/RANKL expression and proinflammatory cytokines during experimental periodontitis in rats. (abst - 2009)
Cannabinoids and the skeleton: From marijuana to reversal of bone loss.
(abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19634029/abstract/Cannabinoids_and_the_skeleto n:_From_marijuana_to_reversal_of_bone_loss_
Activation of CB2 cannabinoid receptors: a novel therapeutic strategy to accelerate osseointegration of dental implants. (abst - 2009)
Marijuana/Cannabis may protect against osteoporosis Cannabis may prevent osteoporosis (news - 2009)
(news - 2009)
http://www.news-medical.net/news/20090813/MarijuanaCannabis-may-protect-against-osteoporosis.aspx
http://news.bbc.co.uk/2/hi/uk_news/scotland/edinburgh_and_east/8199007.stm
515
Hypothalamic regulation of bone. (full 2010)

http://jme.endocrinology-journals.org/cgi/content/full/45/4/175
Cannabinoid Receptors as Target for Treatment of Osteoporosis: A Tale of Two Therapies (full 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001217/?tool=pubmed Tissue Engineering of Cartilage; Can Cannabinoids Help?
(full 2010)
A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20176037 Cannabinoids and Bone: Friend or Foe?
(abst - 2010)
The endocannabinoid signaling system: a marriage of PUFA and musculoskeletal health. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20934863 Control of bone remodeling by nervous system. Nervous system and bone
(abst 2010)
Endocannabinoids are expressed in bone marrow stromal niches and play a role in interactions of hematopoietic stem and progenitor cells with the bone marrow microenvironment (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20826813 The Type 2 Cannabinoid Receptor Regulates Bone Mass and Ovariectomy-Induced Bone Loss by Affecting Osteoblast Differentiation and Bone Formation (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21447627/abstract/The_Type_2_Cannabinoid_Rec eptor_Regulates_Bone_Mass_and_Ovariectomy_Induced_Bone_Loss_by_Affecting_Osteoblast_Differenti ation_and_Bone_Formation_
The endovanilloid/endocannabinoid system: A new potential target for osteoporosis therapy. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21237298 The role of cannabinoid receptors in bone remodeling in a CB1/2 double knockout mouse (abst 2011)
http://www.fasebj.org/cgi/content/meeting_abstract/25/1_MeetingAbstracts/492.5?maxtoshow=&hits=80& RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=160&sortspec=date&resourcety pe=HWCIT
CANNABINOIDS AND BONE: ENDOCANNABINOIDS MODULATE HUMAN OSTEOCLAST FUNCTION IN VITRO. (abst 2011)
Skeletal lipidomics: regulation of bone metabolism by fatty acid amide family. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21557736
516
OVERDOSES Cannabis Indica Poisoning (1899)

Two cases of Poisoning by Cannabis Indica (1900)

Collapse after intravenous injection of hashish.
(full - 1968) (full - 1982)
Accidental Overdose Intoxication: A Hazard of Drug Smuggling

Delirium following ingestion of marijuana present in chocolate cookies (full - 2006) http://www.cnsspectrums.com/aspx/articledetail.aspx?articleid=357 Inadvertent ingestion of marijuana - Los Angeles, California, 2009
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5834a2.htm
(full - 2009)
Accidental cannabis poisoning in children: experience of the Marseille poison center (abst 2009) http://www.ncbi.nlm.nih.gov/pubmed/19541448 Information for Health Care Professionals (revised) - Overdose/Toxicity (Health Canada) (full - 2010)
Accidental cannabis poisoning in children: report of four cases in a tertiary care center from southern Spain (abst 2011)
OVERVIEWS On Being Stoned: A Psychological Study of Marijuana Intoxication (book - 1971) http://www.druglibrary.org/special/tart/tartcont.htm
517
Ganja in Jamaica (book 1976) http://www.cifas.us/cannabis/PDFs/OCRGanjainJamaica.pdf Marijuana Grower's Handbook (text - 1990)
http://www.lycaeum.org/~sky/data/mjgrowers.html
HEMP, THE PLANT THAT CAN SAVE MOTHER EARTH

http://www.ratical.org/renewables/hempHDRT.html#entry
(transcript 1990)
The Emperor Wears No Clothes Cannabis; extracting the medicine
(book - 2007) http://www.jackherer.com/thebook/ (book 2007) (full 2007) (full 2007)
http://mcforadhd.free.fr/Hazekamp%20EXTRACTING%20THE%20MEDICINE.pdf
Cannabinoids: A New Group of Agonists of PPARs
Cannabis and Endocannabinoids: The Old Man and the Teenagers

http://onlinelibrary.wiley.com/doi/10.1002/cbdv.200790143/pdf
Pharmacological actions and therapeutic uses of cannabis and cannabinoids (full 2008)
Medicinal Use of Cannabis in the United States: Historical Prespectives, Current Trends and future Directions (full - 2009)
http://www.letfreedomgrow.com/cmu/JOM_5-3-03-Carter.pdf
Hemp Industry Association - Facts
(article - 2009)
http://www.thehia.org/facts.html
Information for Health Care Professionals- Marihuana (marijuana, cannabis) dried plant for administration by ingestion or other means (Health Canada) (full 2010)
http://www.hc-sc.gc.ca/dhp-mps/marihuana/how-comment/medpract/infoprof/index-eng.php
Cannabis and Its Derivatives: Review of Medical Use

http://www.jabfm.org/cgi/content/full/24/4/452
(full 2011)
Global Commission Drug Report
(links to full in various languages 2011)
http://www.globalcommissionondrugs.org/Report
Introduction to the Endocannabinoid System

(news 2011)
Is Pot Good For You?
(news 2011)
518
PAIN ANTI-EDEMA AND ANALGESIC PROPERTIES OF 9TETRAHYDROCANNABINOL (THC) (abst- 1973)

Analgesic effect of delta-9-tetrahydrocannabinol.
(abst - 1975)
The analgesic properties of delta-9-tetrahydrocannabinol and codeine. (abst - 1975)

Marihuana as a therapeutic agent for muscle spasm or spasticity.

(abst - 1980)
ANALGESIC AND ANTIINFLAMMATORY ACTIVITY OF CONSTITUENTS OF CANNABIS SATIVA L. (full - 1988)

The perceived effects of smoked cannabis on patients with multiple sclerosis. (abst - 1997) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=13 Pain relief with oral cannabinoids in familial Mediterranean fever
(abst - 1997)
Hypoactivity of the Spinal Cannabinoid System Results in NMDA-Dependent Hyperalgesia (full 1998) http://www.jneurosci.org/content/18/1/451.long Doped skin (news - 1998) (full - 1999)
http://www.newscientist.com/article/mg15921434.700-doped-skin.html
Pain modulation by release of the endogenous cannabinoid anandamide

Brain Releases Marijuana-Like Substance In Response To Pain, Study Finds (news - 1999) http://www.sciencedaily.com/releases/1999/10/991013074947.htm
519
Most pain patients gain benefit from cannabis in a British study Therapeutic aspects of cannabis and cannabinoids.
(news - 2000)
(full - 2001)
Are cannabinoids an effective and safe treatment option in the management of pain? A qualitative systematic review (full - 2001)
http://www.ukcia.org/research/EffectiveTreatmentOptionForPain.pdf

(full - 2001) (abst - 2001) (full 2002)
Tetrahydrocannabinol for treatment of chronic pain

A Dramatic Response to Inhaled Cannabis in a Woman with Central Thalamic Pain and Dystonia (full - 2002) http://www.jpsmjournal.com/article/PIIS0885392402004268/fulltext CB2 cannabinoid receptor agonists: pain relief without psychoactive effects? (abst - 2002) http://www.ncbi.nlm.nih.gov/pubmed/12550743 The Pharmacology of Cannabinoid Derivatives: Are There Applications to Treatment of Pain? (abst 2002)
http://medical-journals.healia.com/doc/12134594/The-pharmacology-of-cannabinoid-derivatives-are-thereapplications-to-treatment-of-pain
A preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptoms (full - 2003)
http://www.ukcia.org/research/WholePlantExtractsImproveNeurogenicSymptoms.pdf
Cannabis reduces opioid dose in the treatment of chronic non-cancer pain.

(full - 2003)
Cannabis and Pain Management
(article - 2003) (abst - 2003) (abst - 2003)
http://www.letfreedomgrow.com/articles/can030828.htm
Topical cannabinoid enhances topical morphine antinociception.

Cannabis use for chronic non-cancer pain: results of a prospective survey.

520
Safety and efficacy of dronabinol in the treatment of agitation in patients with Alzheimers disease with anorexia: A retrospective chart review (abst - 2003)
Cannabis Use in HIV for Pain and Other Medical Symptoms

(full - 2004)
Are oral cannabinoids safe and effective in refractory neuropathic pain? (abst - 2004) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=143 Ajulemic acid: A novel cannabinoid produces analgesia without a high (abst - 2004) http://www.ncbi.nlm.nih.gov/pubmed/15240185 Cannabinoids called equivalent to codeine for killing pain High hopes for cannabinoid analgesia (news - 2004) (news - 2004)
http://www.bmj.com/cgi/content/full/329/7460/257?maxtoshow=&hits=80&RESULTFORMAT=&fulltext =cannabis&searchid=1&FIRSTINDEX=2880&resourcetype=HWCIT
Chronic Pain and Cannabinoids
(full 2005)
http://www.drkoprp.com/pdfs/fibromyalgia/CannabinoidsPPM.pdf
CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids (full - 2005) http://www.pnas.org/content/102/8/3093.full Ajulemic acid (IP-751): Synthesis, proof of principle, toxicity studies, and clinical trials (full - 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751505/?tool=pubmed Analgesia through endogenous cannabinoids (analysis - 2005)
Enhancement of transdermal fentanyl and buprenorphine antinociception by transdermal delta9-tetrahydrocannabinol. (abst - 2005) http://www.ncbi.nlm.nih.gov/pubmed/16288738 Cannabis: Use in HIV for Pain and Other Medical Symptoms
(abst - 2005)
Body's Pot-Like Chemicals May Help Curb Pain
(news - 2005)
http://www.webmd.com/pain-management/news/20050622/bodys-pot-like-chemicals-may-help-curb-pain
A multicenter dose-escalation study of the analgesic and adverse effects of an oral cannabis extract (Cannador) for postoperative pain management. (full - 2006)
521
Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751298/?tool=pmcentrez Role of the Cannabinoid System in Pain Control and Therapeutic Implications for the Management of Acute and Chronic Pain Episodes (full - 2006)
Role of cannabinoid receptor agonists in mechanisms of suppression of central pain syndrome. (abst - 2006)
Delta-9-THC based monotherapy in fibromyalgia patients on experimentally induced pain, axon reflex flare, and pain relief (abst - 2006)
Benefits of an add-on treatment with the synthetic cannabinomimetic nabilone on patients with chronic pain - a randomized controlled trial. (abst - 2006)
Synergistic affective analgesic interaction between delta-9-tetrahydrocannabinol and morphine. (abst - 2006)
Local interactions between anandamide, an endocannabinoid, and ibuprofen, a nonsteroidal anti-inflammatory drug, in acute and inflammatory pain (abst - 2006)
Cannabinoid analgesia as a potential new therapeutic option in the treatment of chronic pain. (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16449552 Cannabinoids Enhance Analgesic Effects Of Anti-Inflammatory Drugs, Study Says (news - 2006) http://www.norml.org/index.cfm?Group_ID=6819 In MedPanel Summit, Leading Pain Experts Name Cannabinoids Among Most Promising Approaches to Treating Neuropathic Pain, Assert That Sociopolitical Climate Will Hamper Drug Approvals (news - 2006)
http://www.redorbit.com/news/health/545812/in_medpanel_summit_leading_pain_experts_name_cannabin oids_among_most/index.html?source=r_health
522
Cannabis effective at relieving pain after major surgery

http://www.news-medical.net/?id=17995
(news - 2006)
Cross-sensitization and cross-tolerance between exogenous cannabinoid antinociception and endocannabinoid-mediated stress-induced analgesia (full - 2007)
Antinociceptive Synergy Between the Cannabinoid Receptor Agonist WIN 55,212-2 and Bupivacaine in the Rat Formalin Test (full - 2007)
Dose-dependent effects of smoked cannabis on capsaicin-induced pain and hyperalgesia in healthy volunteers. (full - 2007)
http://journals.lww.com/anesthesiology/Fulltext/2007/11000/Dose_dependent_Effects_of_Smoked_Cannab is_on.16.aspx
Endocannabinoid metabolism and uptake: novel targets for neuropathic and inflammatory pain (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190014/?tool=pubmed Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234438/ Continuous infusion of the cannabinoid WIN 55,2122 to the site of a peripheral nerve injury reduces mechanical and cold hypersensitivity (full - 2007)
Cannabinoids for postoperative pain.
(letter - 2007)
http://journals.lww.com/anesthesiology/Fulltext/2007/02000/Cannabinoids_for_Postoperative_Pain.29.asp x
A cannabinoid agonist differentially attenuates deep tissue hyperalgesia in animal models of cancer and inflammatory muscle pain. (abst 2007)
Cannabis, pain, and sleep: lessons from trials of Sativex, a cannabis-based medicine. (abst - 2007) http://marijuana.researchtoday.net/archive/4/8/1384.htm Pain relief from cannabis depends on how much you smoke
(news - 2007)
Therapeutic potential of cannabis in pain medicine

http://bja.oxfordjournals.org/cgi/reprint/101/1/59
(full - 2008)
523
(full - 2008)
Cannabinoids in chronic pain and palliative care.
(full - 2008)
(full- 2008)
NOVEL SYNERGISTIC OPIOID-CANNABINOID CODRUG FOR PAIN MANAGEMENT (full - 2008) http://www.freepatentsonline.com/y2008/0176885.html Cannabinoid Modulation of Cutaneous A{delta} Nociceptors During Inflammation (full - 2008) http://jn.physiology.org/cgi/reprint/100/5/2794 Cannabinoids in chronic pain and palliative care. (full - 2008) (First in Spanish, then English) http://www.rbaonline.com.br/files/rba/mai08267.pdf A Randomized, Placebo Controlled Cross-Over Trial of Cannabis Cigarettes in Neuropathic Pain (full - 2008) http://www.cmcr.ucsd.edu/geninfo/Wilsey_2008.pdf Nabilone for the treatment of pain in fibromyalgia.
(abst - 2008)
Pain relief with cannabinoids-- the importance of endocannabinoids and cannabinoids for pain therapy (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18671173 Marijuana-Based Drug Reduces Fibromyalgia Pain, Study Suggests (news - 2008) http://www.sciencedaily.com/releases/2008/02/080217214547.htm Scientist Discovers New Molecule to Treat Chronic Pain
(news - 2008)
New Cannabis-Like Drugs Could Block Pain Without Affecting Brain, Says Study (news - 2008) http://www.sciencedaily.com/releases/2008/09/080912091728.htm Cannabis suggests treatment for chronic pain (news - 2008)
http://arstechnica.com/science/news/2008/09/cannabis-suggests-treatment-for-chronic-pain.ars
Dynamic regulation of the endocannabinoid system: implications for analgesia (full - 2009) http://www.molecularpain.com/content/5/1/59
524
The endocannabinoid system and pain.
(full - 2009) (full - 2009)
Cannabinoids: An emerging role in pain management?
http://www.nursingcenter.com/library/JournalArticle.asp?Article_ID=863277
Standardized natural product cannabis in pain management and observations at a Canadian compassion society: a case report (full - 2009)
Systematic Review and Meta-analysis of Cannabis Treatment for Chronic Pain. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19732371 Interaction of the cannabinoid and opioid systems in the modulation of nociception. (abst - 2009)
The analgesic potential of cannabinoids.

(abst - 2009)
Characteristics of patients with chronic pain accessing treatment with medical cannabis in Washington State. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19947069/full_citation/Characteristics_of_patients _with_chronic_pain_accessing_treatment_with_medical_cannabis_in_Washington_State_
Endocannabinoids, Closely Related To Active Ingredients In Cannabis Plant, Can Promote Pain (news - 2009) http://www.sciencedaily.com/releases/2009/09/090911212404.htm Evidence for a Role of Endocannabinoids, Astrocytes and p38 Phosphorylation in the Resolution of Postoperative Pain (full - 2010)
Adjuvant topical therapy with a cannabinoid receptor agonist in facial postherpetic neuralgia. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19744255 A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20176037 Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19896326 Chronic Pain Improved by Cannabis Smoking Study: Smoking pot may ease chronic pain (news 2010)
http://news.softpedia.com/news/Chronic-Pain-Improved-by-Cannabis-Smoking-154254.shtml
(news - 2010)
525
Marijuana better than pharmaceuticals at treating chronic pain, improving mood (news - 2010) http://www.naturalnews.com/029662_marijuana_chronic_pain.html Painkilling System in Brain: Too Much of a Good Thing?
(news - 2010)
Smoking cannabis relieves chronic pain
(news 2010)
http://www.independent.co.uk/life-style/health-and-families/smoking-cannabis-relieves-chronic-pain2067287.html
Pharmacological characterization of AM1710, a putative cannabinoid CB(2) agonist from the cannabilactone class: Antinociception without central nervous system side-effects. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21382397/abstract/Pharmacological_characterizati on_of_AM1710_a_putative_cannabinoid_CB_2__agonist_from_the_cannabilactone_class:_Antinociceptio n_without_central_nervous_system_side_effects_
Cannabis in Palliative Medicine: Improving Care and Reducing Opioid-Related Morbidity (abst - 2011)
http://ajh.sagepub.com/content/early/2011/04/07/1049909111402318.abstract?maxtoshow=&hits=80&RES ULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype=H WCIT
Cannabinoid-opioid interaction in chronic pain.
(abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/22048225/abstract/Cannabinoid_opioid_interaction _in_chronic_pain_
Cannabinoids for Treatment of Chronic Non-Cancer Pain; a Systematic Review of Randomized Trials. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21426373 Treating pain in multiple sclerosis. (abst 2011)
526
Father: Medical marijuana eased pain of my cancer-battling son

(anecdotal 2011) (news 2011)
Marijuana, Narcotics Help Patients Reduce Chronic Pain, Study Finds

http://www.huffingtonpost.com/2011/12/08/marijuana-narcotics-help-patients-reducepain_n_1137416.html
Cannabis brings relief to women suffering from PMS and PMDD symptoms (news 2011)
http://www.examiner.com/cannabis-revolution-in-las-vegas/cannabis-brings-relief-to-women-sufferingfrom-pms-and-pmdd-symptoms
Behavioral effects of pulp exposure in mice lacking cannabinoid receptor 2. (abst 2012)
PANCREATITIS/ PANCREAS Pancreatitis & Medical Marijuana

http://onlinepot.org/medical/pancreatitis.htm
(article - no date)
The cannabinoid 1 receptor antagonist, AM251, prolongs the survival of rats with severe acute pancreatitis. (full - 2005) http://www.jstage.jst.go.jp/article/tjem/207/2/207_99/_article Gpr40 Gene Expression in Human Pancreas and Insulinoma. (abst 2005)
Cannabinoids ameliorate pain and reduce disease pathology in cerulein -induced acute pancreatitis (full - 2007)
Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects (full 2008) http://gut.bmj.com/content/57/8/1140.full Cannabinoids Reduce Markers of Inflammation and Fibrosis in Pancreatic Stellate Cells (full - 2008)
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2253501&rendertype=abstract
527
Expression and function of cannabinoid receptors in mouse islets. (full 2010)

http://www.landesbioscience.com/journals/islets/LiISLETS2-5.pdf
Cannabinoid receptors are coupled to stimulation of insulin secretion from mouse MIN6 beta-cells. (full 2010)
Cannabinoids inhibit insulin receptor signaling in pancreatic -cells.

(full 2011)
(full 2011) (abst 2011)
The role of the endocannabinoid system in islet biology.

PERINATAL HYPOXIC-ISCHEMIC INJURY - also see STROKES Characterization of the neuroprotective effect of the cannabinoid agonist WIN-55212 in an in vitro model of hypoxic-ischemic brain damage in newborn rats. (abst 2006)
Synergistic neuroprotective therapies with hypothermia.
(full 2010)
The cannabinoid WIN55212-2 promotes neural repair after neonatal hypoxia-ischemia. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/21115947 Cannabidiol reduces brain damage and improves functional recovery after acute hypoxiaischemia in newborn pigs. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21654550 The Cannabinoid WIN 55212-2 Mitigates Apoptosis and Mitochondrial Dysfunction After Hypoxia Ischemia. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21909954 Cannabinoid as a neuroprotective strategy in perinatal hypoxic-ischemic injury. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21788999 Therapeutic potential of the endocannabinoid system in perinatal asphyxia (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22127663
528
PARKINSON'S DISEASE Tetrahydrocannabinol potentiates reserpine-induced hypokinesia.

(abst 1981)
Beneficial and adverse effects of cannabidiol in a Parkinson patient with sinemet-induced dystonic dyskinesia. (abst - 1985)

(full - 1986)
Cannabinoids in parkinsonism Cannabis in movement disorders. Why your brain is primed for a high
(3 abstracts - 1999) (abst - 1999) (news - 1999)
http://www.mdvu.org/emove/article.asp?ID=586
Enhanced levels of endogenous cannabinoids in the globus pallidus are associated with a reduction in movement in an animal model of Parkinsons disease (full - 2000)
Experimental parkinsonism alters endocannabinoid degradation: implications for striatal glutamatergic transmission. (full 2002) http://www.jneurosci.org/content/22/16/6900.long US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants
(full - 2003)

(abst - 2003)
Survey on cannabis use in Parkinson's disease: subjective improvement of motor symptoms. (abst - 2004)
Marijuana Compounds May Aid Parkinson's Disease

http://cannabisnews.com/news/19/thread19725.shtml
(news - 2004)
529
Depression in Parkinson's disease is related to a genetic polymorphism of the cannabinoid receptor gene (CNR1) (full - 2005)

(abst 2005)

Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: importance of antioxidant and cannabinoid receptor-independent properties. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17196181 Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinson's disease models. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17287809 Cannabinoids and neuroprotection in motor-related disorders.
(abst - 2007)
Marijuana Against Parkinson?
(news 2007) (news - 2007) (news 2007)
http://news.softpedia.com/news/Marijuana-Against-Parkinson-46701.shtml
Marijuana-Like Chemicals Helps Treat Parkinson's

Parkinsons' Helped By Marijuana-Lke Chemicals In Brain

Enhancing Activity Of Marijuana-Like Chemicals In Brain Helps Treat Parkinson's Symptoms In Mice (news - 2007)
(full - 2008)
Paraquat induces apoptosis in human lymphocytes: protective and rescue effects of glucose, cannabinoids and insulin-like growth factor-1. (abst 2008)
530
The cannabinoid CP55,940 prolongs survival and improves locomotor activity in Drosophila melanogaster against paraquat: implications in Parkinson's disease. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18538428 Cannabidiol: a promising drug for neurodegenerative disorders?
(full - 2009)
WIN55,212-2, a Cannabinoid Receptor Agonist, Protects Against Nigrostriatal Cell Loss in the MPTP Mouse Model of Parkinsons Disease (full - 2009)
Cannabidiol for the treatment of psychosis in Parkinsons disease
(abst - 2009)
http://jop.sagepub.com/cgi/content/abstract/23/8/979?maxtoshow=&hits=80&RESULTFORMAT=&fulltex t=cannabinoid&searchid=1&FIRSTINDEX=1920&resourcetype=HWCIT
Cannabinoids and Dementia: A Review of Clinical and Preclinical Data

(full 2010)
CannabinoidDopamine Interaction in the Pathophysiology and Treatment of CNS Disorders (full 2010) http://onlinelibrary.wiley.com/doi/10.1111/j.1755-5949.2010.00144.x/full Loss of cannabinoid CB1 receptor expression in the 6-hydroxydopamine-induced nigrostriatal terminal lesion model of Parkinson's disease in the rat. (abst 2010)
Therapeutic Potential of Cannabinoids in the Treatment of Neuroinflammation Associated with Parkinson's Disease (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21568925/abstract/Therapeutic_Potential_of_Cann abinoids_in_the_Treatment_of_Neuroinflammation_Associated_with_Parkinson%27s_Disease_
Regional changes in type 1 cannabinoid receptor availability in Parkinson's disease in vivo (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21459482/abstract/Regional_changes_in_type_1_c annabinoid_receptor_availability_in_Parkinson%27s_disease_in_vivo_
Homeostatic changes of the endocannabinoid system in Parkinson's disease. (abst 2011)

http://www.unboundmedicine.com/medline/ebm/record/21412829/abstract/Homeostatic_changes_of_the_e ndocannabinoid_system_in_Parkinson%27s_disease_
531
Prospects for cannabinoid therapies in basal ganglia disorders.

(abst 2011)
Symptom-relieving and neuroprotective effects of the phytocannabinoid D(9) -THCV in animal models of Parkinson's disease (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21323909/abstract/Symptom_relieving_and_neuro protective_effects_of_the_phytocannabinoid_D_9___THCV_in_animal_models_of_Parkinson%27s_disea se_
Cannabinoid Receptor Type 1 Protects Nigrostriatal Dopaminergic Neurons against MPTP Neurotoxicity by Inhibiting Microglial Activation. (abst 2011)
(news 2011)
PATENTS RELATED TO CANNABIS US Patent 4189491 - Tetrahydrocannabinol in a method of treating glaucoma (full - 1980) http://www.patentstorm.us/patents/4189491.html Process for preparing cannabichromene (full - 1982)
http://www.patentstorm.us/patents/4315862/description.html
Patent 4758597 Carenadiol and derivatives (full 1988)

US Patent 5389375 - Stable suppository formulations effecting bioavailability of 9 -thc (full - 1995) http://www.patentstorm.us/patents/5389375/fulltext.html US Patent 5508037 - Stable suppository formulations effecting bioavailability of 9 THC (full - 1996) http://www.patentstorm.us/patents/5508037/fulltext.html Patent 5605928 - Antiemetic compositions (full 1997)
Patent 5631297 - Anandamides useful for the treatment of intraocular hypertension, ophthalmic compositions containing the same and methods of use of the same (full 1997) http://www.patentstorm.us/patents/5631297/fulltext.html US Patent 6132762 - Transcutaneous application of marijuana
(full - 2000)
532
US Patent 6113940 - Cannabinoid patch and method for cannabis transdermal delivery (full 2000) http://www.patentstorm.us/patents/6113940/fulltext.html US Patent 6328992 - Cannabinoid patch and method for cannabis transdermal delivery (full - 2001) http://www.patentstorm.us/patents/6328992/fulltext.html US Patent 6383513 - Compositions comprising cannabinoids
(nasal spray) (full - 2002)
US Patent Application 20050042172 - Administration of medicaments by vaporisation (full - 2002) http://www.patentstorm.us/applications/20050042172/fulltext.html Patent 6410588 Use of cannabinoids as anti-inflammatory agents
(full 2002)
US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants (full - 2003) (Assignee (owner)- the US GOVERNMENT!)
Patent 6503492 - Antiperspirant or deodorant compositions

(full 2003)
20070151149 - Methods for altering the level of phytochemicals in plant cells by applying wave lengths of light from 400 nm to 700 nm and apparatus therefore (full - 2004) http://www.patentstorm.us/applications/20070151149/fulltext.html US Patent Application 2004004905 - Method for producing an extract from cannabis plant matter, containing a tetrahydrocannabinol and a cannabidiol and cannabis extracts (full - 2004) http://www.freepatentsonline.com/y2004/0049059.html US Patent 6713048 - 9 tetrahydrocannabinol (9 THC) solution metered dose inhalers and methods of use (full - 2004) http://www.patentstorm.us/patents/6713048/fulltext.html Patent 67130489 tetrahydrocannabinol (9 THC) solution metered dose inhalers and methods of use (full 2004) http://www.patentstorm.us/patents/6713048/fulltext.html US Patent 6974568 - Treatment for cough (full - 2005)
US Patent Application 20050266108 - Methods of purifying cannabinoids from plant material (full - 2005) http://www.patentstorm.us/applications/20050266108/fulltext.html US Patent Application 20050079136 - Aerosol formulations of delta tetrahydrocannabinol (full 2005)
533
US Patent 6949582 - Method of relieving analgesia and reducing inflamation using a cannabinoid delivery topical liniment (full - 2005)
20050070596 - Methods for treatment of inflammatory diseases using CT-3 or analogs thereof (full - 2005) http://www.patentstorm.us/applications/20050070596/fulltext.html Method of relieving analgesia and reducing inflamation using a cannabinoid delivery topical liniment (full - 2005) http://www.patentstorm.us/patents/6949582/fulltext.html US Patent Application 20060160888 - Room-temperature stable dronabinol formulations (full 2006) http://www.patentstorm.us/applications/20060160888/fulltext.html US Patent 7088914 - Device, method and resistive element for vaporizing a medicament (full - 2006) http://www.patentstorm.us/patents/7088914/fulltext.html US Patent Application 20060167084 - Delta-9-THC compositions and methods for treating symptoms associated with multiple sclerosis (full - 2006 )
US Patent 7025992 - Pharmaceutical formulations

(full - 2006)
US Patent Application 20060039959 - Film-Shaped Mucoadhesive Administration Forms For Administering Cannabis Agents (full 2006)
US Patent Application 20060242899 - Method of cultivating plants

http://www.freepatentsonline.com/y2006/0242899.html
full - 2006)
US Patent 7109245 - Vasoconstrictor cannabinoid analogs

(full - 2006)
US Patent Application 20070020193 - Dronabinol compositions and methods for using same (full 2007) http://www.patentstorm.us/applications/20070020193/fulltext.html 20080057117 - PHARMACEUTICAL COMPOSITION MADE UP OF CANNIBUS EXTRACTS (full - 2007) http://www.patentstorm.us/applications/20080057117/fulltext.html US Patent Application 20070041994 - Compositions and methods for treating prostate disorders ( full 2007) http://www.patentstorm.us/applications/20070041994/fulltext.html US Patent Application 20070049645 - Anti-nausea and anti-vomiting activity of cannabidiol compounds (full 2007)
US Patent Application 20070099987 - Treating or preventing diabetes with cannabidiol (full 2007) http://www.patentstorm.us/applications/20070099987/fulltext.html
534
Patent 7344736 - Extraction of pharmaceutically active components from plant materials (full 2008) http://www.patentstorm.us/patents/7344736/description.html 20080275237 - Method for Obtaining Pure Tetrahydrocannabinol
(full 2008)
US Patent 7402686 - Cannabinoid crystalline derivatives and process of cannabinoid purification (full - 2008) http://www.patentstorm.us/patents/7402686/fulltext.html US Patent 7399872 - Conversion of CBD to -THC and -THC
(full - 2008) (full 2008)
US Patent Application 20080112895 - Aqueous dronabinol formulations

US Patent Application 20080181942 - Delta-9-THC compositions and methods for treating symptoms associated with multiple sclerosis (full 2008)
US Patent Application 20080262099 - Inhibition of Tumour Cell Migration (full 2008) http://www.patentstorm.us/applications/20080262099/fulltext.html Op-Ed: US Government Holds Patent For Medical Marijuana, Shows Hypocrisy (news 2008) http://www.digitaljournal.com/article/257008 Patent 7524881 - Production of 9 tetrahydrocannabinol
(full 2009)
US Patent Application 20090324797 - MODULATING PLANT OIL LEVELS (full 2009) http://www.patentstorm.us/applications/20090324797/fulltext.html US Patent 7622140 - Processes and apparatus for extraction of active substances and enriched extracts from natural products (full - 2009)
US Patent Application 20090197941 - Pharmaceutical Compositons for the Treatment of Chronic Obstructive Pulmonary Disease (full 2009)
US Patent Application 20090005461 - Use of Cannabidiol in the Treatment of Hepatitis (full 2009) http://www.patentstorm.us/applications/20090005461/fulltext.html NEW USE FOR CANNABINOID-CONTAINING PLANT EXTRACTS Patent application number: 20100249223 (full - 2010)
535
CANNABINOID-CONTAINING PLANT EXTRACTS AS NEUROPROTECTIVE AGENTS Patent application number: 20100239693 (full - 2010)
Patent application title: PHARMACOLOGICAL TREATMENT OF PSORIASIS (full 2010) http://www.faqs.org/patents/app/20080255224 US Patent Application 20100012118 - Medicament dosage for inhaler
(full 2010)
Patent 7741365 Peripheral cannabinoid receptor (CB2) selective ligands (full 2010) http://www.patentstorm.us/patents/7741365/fulltext.html Patent 7816143 Oral detection test for cannabinoid use
(full - 2010)
US Patent Application 20100204312 - METHODS AND COMPOSITIONS FOR TREATING CANCER (full - 2010)
US Patent Application 20100158973 - THERAPEUTIC USES OF CANNABIDIOL COMPOUNDS (full 2010) http://www.patentstorm.us/applications/20100158973/fulltext.html US Patent Application 20110097283 - CHEWING GUM COMPOSITIONS COMPRISING CANNABINOIDS (full 2011)
US Patent Application 20110052694 - USE OF CANNABIDIOL PRODRUGS IN TOPICAL AND TRANSDERMAL ADMINISTRATION WITH MICRONEEDLES (full 2011) http://www.patentstorm.us/applications/20110052694/fulltext.html US Patent Application 20110073120 - Smoke and Odor Elimination Filters, Devices and Methods (full 2011) http://www.patentstorm.us/applications/20110073120/fulltext.html US Patent Application 20110020945 - ORAL DETECTION TEST FOR CANNABINOID USE (full 2011)
US Patent Application 20110082195 - NEW USE FOR CANNABINOIDS (full 2011) http://www.patentstorm.us/applications/20110082195/fulltext.html
536
PEA PALMITOYLETHANOLAMIDE - endocannabinoid , GPR55 & GPR119 agonist Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells (full - 2001)
Anticonvulsant activity of N-palmitoylethanolamide, a putative endocannabinoid, in mice. (abst 2001) http://www.ncbi.nlm.nih.gov/pubmed/11442148 Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat (full - 2002)
The search for the palmitoylethanolamide receptor.

(abst 2005)
Finding of endocannabinoids in human eye tissues: implications for glaucoma. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/15823551 Selective antiepileptic effects of N-palmitoylethanolamide, a putative endocannabinoid. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/15461672 Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration. (abst 2006)
Effects of palmitoylethanolamide on signaling pathways implicated in the development of spinal cord injury. (full 2008) http://jpet.aspetjournals.org/content/326/1/12.long Adjuvant treatment of atopic eczema: assessment of an emollient containing Npalmitoylethanolamine (ATOPA study). (abst - 2008)
Anti-inflammatory effect of palmitoylethanolamide on human adipocytes. (abst 2009) http://www.ncbi.nlm.nih.gov/pubmed/19131941 Protective role of palmitoylethanolamide in contact allergic dermatitis.
(abst 2010)
Levels of endocannabinoids and palmitoylethanolamide and their pharmacological manipulation in chronic granulomatous inflammation in rats. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/19931394 Circulating and hepatic endocannabinoids and endocannabinoid-related molecules in patients with cirrhosis. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/19840245
537
Misdiagnosed chronic pelvic pain: pudendal neuralgia responding to a novel use of palmitoylethanolamide. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20345619 Effect of palmitoylethanolamide-polydatin combination on chronic pelvic pain associated with endometriosis: preliminary observations. (abst 2010)

(abst 2010)
Chocolate: The Good, the Bad and the Angry
(news - 2010)
Administration of URB597, oleoylethanolamide or palmitoylethanolamide increases waking and dopamine in rats. (full 2011)
Palmitoylethanolamide counteracts reactive astrogliosis induced by beta-amyloid peptide. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21255263 Use of palmitoylethanolamide in the entrapment neuropathy of the median in the wrist. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21483401 Effects of palmitoylethanolamide on release of mast cell peptidases and neurotrophic factors after spinal cord injury. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21354467 Effects of palmitoylethanolamide on the cutaneous allergic inflammatory response in Ascaris hypersensitive Beagle dogs. (abst 2011)
PHARC Mutations in ABHD12 cause the neurodegenerative disease PHARC: An inborn error of endocannabinoid metabolism. (full 2011)
538
The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2arachidonoylglycerol signalling through cannabinoid receptors (full 2011)
The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2arachidonoylglycerol signalling through cannabinoid receptors. (abst 2012)
PHYTOCANNABINOIDS/ PLANT EXTRACTS - also see THC, CBD ACCESSING 0.5 to 2.0 GRAMS CBD FRACTIONATING THE PHYTOCANNABINOIDS BY THEIR VAPORIZATION POINTS (article - no date )
http://forum.grasscity.com/medical-marijuana/610429-need-cbd.html
Cannabinoids (encyclopedia entry)
Cannabis Indica (U. S. P.)Indian Cannabis. King's American Dispensatory (1898)

http://www.henriettesherbal.com/eclectic/kings/cannabis.html
Chemical basis of hashish activity.
(abst - 1970)
Anticonvulsant Action of Cannabis in the Rat: Role of Brain Monoamines. (abst 1978)
Intraocular pressure following systemic administration of cannabinoids.

(abst - 1982)
Ocular hypotension, ocular toxicity, and neurotoxicity in response to marihuana extract and cannabidiol. (abst 1984) http://www.ncbi.nlm.nih.gov/pubmed/6098513 Side effects of pharmaceuticals not elicited by comparable herbal medicines: the case of tetrahydrocannabinol and marijuana. (abst 1999)
Immunoactive cannabinoids: Therapeutic prospects for marijuana constituents (full - 2000) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC34030/?tool=pubmed Variations of D9-THC content in single plants of hemp varieties
(full - 2000)
539
(abst - 2000)
Cannabis and Cannabis Extracts: Greater Than the Sum of Their Parts? (full - 2001)
http://www.cannabis-med.org/membersonly/mo.php?aid=2001-03-04&fid=2001-03-04-7&mode=p&sid=
Chapter 3: Cannabis and Marinol Compared Natural cannabis 'better than extracts'
(book excerpt - 2001)
http://www.or-coast.net/contigo/PDF%201%20Files/chpt_3.pdf
(news - 2001)
Whether whole plant Cannabis extracts can improve intractable neurogenic symptoms? (full - 2003) http://www.ukcia.org/research/WholePlantExtractsImproveNeurogenicSymptoms.pdf Cannabis can help MS sufferers (news - 2003)
Efficacy, safety and tolerability of an orally administered cannabis extract in the treatment of spasticity in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled, crossover study. (full - 2004)
http://www.ukcia.org/research/EfficacySafetyTolerabilityInMSSpasticityTreatment.pdf
Initial experiences with medicinal extracts of cannabis for chronic pain: Results from 34 N of 1 studies (full - 2004) http://www.ukcia.org/research/InitialExperiencesChronicPain.pdf Efficacy of two cannabis based medicinal extracts for relief of central neuropathic pain from brachial plexus avulsion: results of a randomised controlled trial (full - 2004)
http://www.ukcia.org/research/CentralNeuropathicPainEfficacy.pdf
Cannabis truly helps multiple sclerosis sufferers
(news - 2004) (full - 2005)
Plant cannabinoids: a neglected pharmacological treasure trove.

Chemical constituents of marijuana: the complex mixture of natural cannabinoids. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/16199061 A tale of two cannabinoids:The therapeutic rationale for combining tetrahydrocannabinol and cannabidiol. (full - 2006)
Unheated Cannabis sativa extracts and its major compound THC-acid have potential immuno-modulating properties not mediated by CB1 and CB2 receptor coupled pathways. (abst - 2006)
540
The multidrug transporter ABCG2 (BCRP) is inhibited by plant-derived cannabinoids. (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190019/?tool=pubmed Endocannabinoids and Related Compounds: Walking Back and Forth between Plant Natural Products and Animal Physiology (full - 2007)
Medicinal chemistry endeavors around the phytocannabinoids.

(abst - 2007)

Pain relief with cannabinoids-- the importance of endocannabinoids and cannabinoids for pain therapy (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18671173 Antihyperalgesic effect of a Cannabis sativa extract in a rat model of neuropathic pain: mechanisms involved. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18618522 Interaction of plant cannabinoids with the multidrug transporter ABCC1 (MRP1). (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18619955 Immunomodulatory lipids in plants: plant fatty acid amides and the human endocannabinoid system. (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/18275004 PKS activities and biosynthesis of cannabinoids and flavonoids in Cannabis sativa L. plants (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18854334 Non-psychotropic plant cannabinoids:new therapeutic opportunities from an ancient herb (full - 2009 )
1.0 Chemistry
(full - 2009)
http://www.hc-sc.gc.ca/dhp-mps/marihuana/how-comment/medpract/infoprof/chemistry-chimieeng.php#a1_1
541
Evaluation of prevalent phytocannabinoids in the acetic acid model of visceral nociception (full - 2009)
Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19729208 Phytocannabinoids and endocannabinoids.
(abst - 2009)
Pharmacological and therapeutic secrets of plant and brain (endo)cannabinoids. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/18777572 Phytocannabinoid scientists unveils lozenge to treat H1N1 swine flu and H5N1 bird flu (news/ad - 2009)
http://www.examiner.com/examiner/x-7002-Pittsburgh-History-Examiner~y2009m6d11Phytocannabinoid-scientists-unveils-lozenge-to-treat--H1N1-swine-flu-and-H5N1-bird-flu#comments
Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L. (full 2010)
The plant cannabinoid Delta9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice. (full 2010)
Phytocannabinoids beyond the Cannabis plant do they exist?

(full - 2010)
Non-CB1, non-CB2 receptors for endocannabinoids, plant cannabinoids, and synthetic cannabimimetics: focus on G-protein-coupled receptors and transient receptor potential channels. (abst 2010)
A low-9tetrahydrocannabinol cannabis extract induces hyperphagia in rats. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20975531 Cannabis constituents modulate 9-tetrahydrocannabinol-induced hyperphagia in rats. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20349049 Preliminary efficacy and safety of an oromucosal standardized cannabis extract in chemotherapy-induced nausea and vomiting. (abst - 2010)
542
Scientists Find New Sources of Plant Cannabinoids Other than Medical Marijuana? (news 2010)
Nature's (Legal) Cannabinoids
(news - 2010) (full 2011)
Evaluation of the cyclooxygenase inhibiting effects of six major cannabinoids isolated from Cannabis sativa. (full 2011) http://www.jstage.jst.go.jp/article/bpb/34/5/774/_pdf Treatment of Crohn's disease with cannabis: an observational study. (full 2011)
http://www.ima.org.il/imaj/ar11aug-01.pdf
The role of phytochemicals in the treatment and prevention of dementia.
(abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21639405/abstract/The_role_of_phytochemicals_i n_the_treatment_and_prevention_of_dementia_
Neuroprotective effects of phytocannabinoid-based medicines in experimental models of Huntington's disease. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21674569 Prospects for cannabinoid therapies in basal ganglia disorders.
(abst 2011)
Cannabinoids: occurrence and medicinal chemistry. (abst 2011)

http://www.unboundmedicine.com/medline/ebm/record/21254969/abstract/Cannabinoids:_occurrence_and _medicinal_chemistry_
Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21749363 Acute and chronic cannabinoid extracts administration affects motor function in a CREAE model of multiple sclerosis. (abst 2011)
Phytocannabinoids as novel therapeutic agents in CNS disorders

(abst 2011)
Cannabis sativa and the endogenous cannabinoid system: therapeutic potential for appetite regulation. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21213357 Non-9tetrahydrocannabinol phytocannabinoids stimulate feeding in rats. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22157176
543
The Endocannabinoid System: Plant-Derived Cannabinoids in Diabetes and Diabetic Complications. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22155112 Marijuana, endocannabinoids, and epilepsy: Potential and challenges for improved therapeutic intervention. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/22178327 Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. (abst 2011)
POISONING - ORGANOPHOSPHATE Modulation of paraoxon toxicity by the cannabinoid receptor agonist WIN 55,212-2. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16956707 Monoacylglycerol lipase inhibition by organophosphorus compounds leads to elevation of brain 2-arachidonoylglycerol and the associated hypomotility in mice. (abst 2006)
Activation of the endocannabinoid system by organophosphorus nerve agents (abst - 2008) http://www.nature.com/nchembio/journal/v4/n6/abs/nchembio.86.html Behavioral sequelae following acute diisopropylfluorophosphate intoxication in rats: comparative effects of atropine and cannabinomimetics. (full 2010)
Cannabinoid Receptor Agonist WIN-55,212-2 Protects Differentiated PC12 Cells From Organophosphorus- Induced Apoptosis (abst 2010)
http://ijt.sagepub.com/content/29/2/201.abstract
Effect of Developmental Chlorpyrifos Exposure on Endocannabinoid Metabolizing Enzymes in the Brain of Juvenile Rats. (abst 2011)
Comparative effects of chlorpyrifos in wild type and cannabinoid Cb1 receptor knockout mice. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21672545
POISONING - PARAQUAT An effect of paraquat on the lungs of rabbits. Its implications in smoking contaminated marihuana. (full - 1978) http://chestjournal.chestpubs.org/content/74/4/418.long
544
Paraquat goes to pot.
(full - 1978)
http://chestjournal.chestpubs.org/content/74/4/358.long
Paraquat and marihuana. Assessing the hazard.

(full - 1978) (full -1983)
Paraquat and marijuana: epidemiologic risk assessment.
Paraquat induces apoptosis in human lymphocytes: protective and rescue effects of glucose, cannabinoids and insulin-like growth factor-1. (abst 2008)
The cannabinoid CP55,940 prolongs survival and improves locomotor activity in Drosophila melanogaster against paraquat: implications in Parkinson's disease. (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/18538428 Protective effects of the synthetic cannabinoids CP55,940 and JWH-015 on rat brain mitochondria upon paraquat exposure. (abst 2010)
POST-OPERATIVE PAIN Cannabinoid CB2 receptor agonist activity in the hindpaw incision model of postoperative pain. (abst - 2005) http://www.ncbi.nlm.nih.gov/pubmed/16316653 A multicenter dose-escalation study of the analgesic and adverse effects of an oral cannabis extract (Cannador) for postoperative pain management. (full - 2006)
Analgesic and adverse effects of an oral cannabis extract (Cannador) for postoperative pain (abst - 2006) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=184 Delta(9)-tetrahydrocannabinol and the opioid receptor agonist piritramide do not act synergistically in postoperative pain (abst 2006)
Cannabis effective at relieving pain after major surgery

(news - 2006) (news - 2006)
Cannador: Drug from cannabis plant-extract to reduce surgery pain
545
Cannabinoid Receptor Agonist Significantly Reduces Post-Operative Pain, Study Says (news 2007) http://norml.org/index.cfm?Group_ID=7246 Evidence for a Role of Endocannabinoids, Astrocytes and p38 Phosphorylation in the Resolution of Postoperative Pain (full - 2010)
Compound boosts marijuana-like chemical in the body to relieve pain at injury site (news - 2010) http://www.eurekalert.org/pub_releases/2010-09/uoc--cbm092010.php
POST TRAUMATIC STRESS DISORDER/ PTSD Never fear, cannabinoids are here
http://mcforadhd.free.fr/naturefear.pdf
(article - 2002)
The endogenous cannabinoid system controls extinction of aversive memories. (abst - 2002) http://www.ncbi.nlm.nih.gov/pubmed/12152079 'Natural' cannabis manages memory
(news - 2002) (news - 2002) (news - 2002) (news - 2002)
Study: Marijuana Eases Traumatic Memories

Cannabis-like Brain Chemical Blocks Out Bad Memories Endocannabinoids extinguish bad memories in the brain Marijuana-Like Compound Banishes Fear Natural high helps banish bad memories Israel to soothe soldiers with marijuana (news - 2002) (news - 2002) (news - 2004)
http://www.scientificamerican.com/article.cfm?id=cannabis-like-brain-chemi
http://www.webmd.com/anxiety-panic/news/20020802/marijuana-like-compound-banishes-fear
http://www.newscientist.com/article/dn2616-natural-high-helps-banish-bad-memories.html
http://newsmine.org/content.php?ol=war-on-terror/israel/israel-to-soothe-soldiers-with-marijuana.txt
546
Enhancing Cannabinoid Neurotransmission Augments the Extinction of Conditioned Fear (full - 2005) http://www.nature.com/npp/journal/v30/n3/full/1300655a.html Cannabinoid CB1 Receptor Mediates Fear Extinction via Habituation-Like Processes (full - 2006)
Aversive memory reactivation engages in the amygdala only some neurotransmitters involved in consolidation. (full 2006) http://learnmem.cshlp.org/content/13/4/426.long PTSD and Cannabis: A Clinician Ponders Mechanism of Action
http://ccrmg.org/journal/06spr/perspective2.html
(news - 2006)
Cannabis Eases Post Traumatic Stress

http://ccrmg.org/journal/06spr/ptsd.html
(news - 2006) (full - 2007)
Modulation of Fear and Anxiety by the Endogenous Cannabinoid System

Inhibition of fatty-acid amide hydrolase accelerates acquisition and extinction rates in a spatial memory task. (full 2007)
http://www.nature.com/npp/journal/v32/n5/pdf/1301224a.pdf
Posttraumatic stress symptom severity predicts marijuana use coping motives among traumatic event-exposed marijuana users (abst - 2007)
Medical Marijuana: PTSD Medical Malpractice
(news - 2007) (news - 2007)
http://salem-news.com/articles/june142007/leveque_61407.php
Cannabis for the Wounded - Another Walter Reed Scandal

http://www.libertypost.org/cgi-bin/readart.cgi?ArtNum=179973&Disp=11
Association of the Cannabinoid Receptor Gene (CNR1) With ADHD and Post-Traumatic Stress Disorder (full 2008)
Marijuana Therapy for Veterans with PTSD
(article 2008)
http://www.benefitsofmarijuana.com/ask/reader-questions/marijuana-therapy-for-veterans-with-ptsd/
Cannabinoid Receptor Activation in the Basolateral Amygdala Blocks the Effects of Stress on the Conditioning and Extinction of Inhibitory Avoidance (full - 2009)
http://www.jneurosci.org/cgi/content/full/29/36/11078?maxtoshow=&hits=10&RESULTFORMAT=&fullt ext=Dr.+Irit+Akirav+&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
The use of a synthetic cannabinoid in the management of treatment-resistant nightmares in posttraumatic stress disorder (PTSD). (abst - 2009)
547
Cannabinoid receptors in brain: pharmacogenetics, neuropharmacology, neurotoxicology, and potential therapeutic applications (abst 2009) http://pharmgkb.org/pmid/19897083 Patients with post-traumatic stress disorder may benefit from synthetic marijuana (news - 2009)
http://www.healthjockey.com/2009/11/05/patients-with-post-traumatic-stress-disorder-may-benefit-fromsynthetic-marijuana/
Marijuana could alleviate symptoms of PTSD
(news - 2009) (news - 2009)
http://israel21c.org/health/marijuana-could-alleviate-symptoms-of-ptsd
Marijuana could prove helpful for post-traumatic stress disorder patients.
http://www.thefreelibrary.com/Marijuana+could+prove+helpful+for+post-traumatic+stress+disorder...a0211332139
'Pot' may help combat PTSD U. of Haifa study shows

http://www.vawatchdog.org/09/nf09/nfnov09/nf110509-7.htm
(news - 2009) (full 2010)
PTSD contributes to teen and young adult cannabis use disorders.

Cannabinoids modulate hippocampal memory and plasticity.

(abst 2010)
The relationship between substance use and posttraumatic stress disorder in a methadone maintenance treatment program. (abst 2010)
V.A. Easing Rules for Users of Medical Marijuana (news 2010)

http://www.nytimes.com/2010/07/24/health/policy/24veterans.html
Cannabis and PTSD by Michael McKenna
(anecdotal - 2010)
http://marijuana-uses.com/cannabis-and-ptsd-by-michael-mckenna/
The role of cannabinoids in modulating emotional and non-emotional memory processes in the hippocampus. (full 2011)
Cannabinoids prevent the development of behavioral and endocrine alterations in a rat model of intense stress. (full 2011)
Cannabinoids Prevent the Development of Behavioral and Endocrine Alterations in a Rat Model of Intense Stress. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21918506 Posttraumatic stress disorder and Cannabis use in a nationally representative sample. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21480682
548
Cannabinoid receptor expression and phosphorylation are differentially regulated between male and female cerebellum and brain stem after repeated stress: Implication for PTSD and drug abuse. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21600961 Effect of cannabidiol on sleep disruption induced by the repeated combination tests consisting of open field and elevated plus-maze in rats. (abst 2011)
Cannabinoids Prevent the Development of Behavioral and Endocrine Alterations in a Rat Model of Intense Stress. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21918506 Anti-Aversive Effects of Cannabidiol on Innate Fear-Induced Behaviors Evoked by an Ethological Model of Panic Attacks Based on a Prey vs the Wild Snake Epicrates cenchria crassus Confrontation Paradigm. (abst - 2011)
Medical cannabis use in post-traumatic stress disorder: a naturalistic observational study. (abst 2011) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=481 Cannabis use among military veterans after residential treatment for posttraumatic stress disorder. (abst 2011) http://marijuana.researchtoday.net/archive/8/9/5260.htm Marijuana Administration After a Traumatic Experience May Prevent Post-Traumatic Stress Symptoms, Rat Study Suggests (news 2011)
Medical marijuana turns former soldier's life around
(news 2011)
http://www.examiner.com/cannabis-culture-in-phoenix/medical-marijuana-turns-former-soldier-s-lifearound
Marijuana blocks PTSD symptoms in rats: study
(news - 2011)
http://medicalxpress.com/news/2011-09-marijuana-blocks-ptsd-symptoms-rats.html
Opposing Roles for Cannabinoid Receptor Type-1 (CB(1)) and Transient Receptor Potential Vanilloid Type-1 Channel (TRPV1) on the Modulation of Panic-Like Responses in Rats. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/21937980
PRADER WILLI SYNDROME Psychiatric adverse effects of rimonobant in adults with Prader Willi syndrome. (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038245/?tool=pubmed
549
PREGNANCY/ PRENATAL EXPOSURE

also see PERINATAL HYPOXIC-ISCHEMIC INJURY, CHILDREN
(article - no date)
Effects of Alcohol and Cannabis during Labor.
(article - 1930) (on page 2)
http://jama.ama-assn.org/cgi/reprint/94/15/1164a?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid=1&FIRSTINDEX=3360&res ourcetype=HWCIT
Nonmutagenic action of cannabinoids in vitro
(abst - 1978)
http://content.karger.com/ProdukteDB/produkte.asp?Doi=136789
Teratologic evaluation of synthetic delta 9-tetrahydrocannabinol in rabbits. (abst 1979) http://www.ncbi.nlm.nih.gov/pubmed/473088 Acute effects of marihuana smoking on prolactin levels in human females. (abst - 1985)
Effects of prenatal exposure to cannabinoids.
(abst 1985)
A comparison of the effects of prenatal exposure to tobacco, alcohol, cannabis and caffeine on birth size and subsequent growth (abst - 1987)
Poor and pregnant: perinatal ganja use in rural Jamaica. (abst 1989)
Marijuana Use in Pregnancy and Pregnancy Outcome.

(abst 1990)
Five-year follow-up of rural Jamaican children whose mothers used marijuana during pregnancy. (abst 1991) http://www.ncbi.nlm.nih.gov/pubmed/1957518
550
Prenatal marijuana use and neonatal outcome.

(abst 1991)
Analysis of Facial Shape in Children Gestationally Exposed to Marijuana, Alcohol, and/or Cocaine (abst - 1992)
http://pediatrics.aappublications.org/cgi/content/abstract/89/1/67?maxtoshow=&hits=80&RESULTFORM AT=&fulltext=marihuana&searchid=1&FIRSTINDEX=960&resourcetype=HWCIT
Tobacco and marijuana use on offspring growth from birth through 3 years of age. (abst - 1992)
THREE THINGS MARIJUANA DOESN'T DO

(news - 1992)
Prenatal Marijuana Exposure and Neonatal Outcomes in Jamaica : An Ethnographic Study (full - 1994) http://www.druglibrary.org/Schaffer/hemp/medical/can-babies.htm The preimplantation mouse embryo is a target for cannabinoid ligand-receptor signaling. (full - 1995) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC40821/ Prenatal exposure to marihuana and tobacco during infancy, early and middle childhood: effects and an attempt at synthesis. (abst 1995)
Maternal cannabis use and birth weight: a meta-analysis Use of Marijuana During Pregnancy Dr. Melanie Dreher, reefer researcher Cannabis and pregnancy (full - 1999) (news - 1999)
(abst 1997)
http://www.ingentaconnect.com/content/carfax/cadd/1997/00000092/00000011/art00015
(book excerpt - 1997) (interview - 1998)
http://www.mothering.com/pregnancy-birth/use-of-marijuana-during-pregnancy
http://www.ukcia.org/research/CannabisAndPregnancy.php
Ganja mothers, ganja babies
551
Dysregulated Cannabinoid Signaling Disrupts Uterine Receptivity for Embryo Implantation (full - 2001) http://www.jbc.org/content/276/23/20523.full Menstrual cramps, morning sickness and labour pain (anecdotal 2001)
http://www.ukcia.org/medical/showmedicaltestimony.php?articleid=12
Contrasting effects of WIN 55212-2 on motility of the rat bladder and uterus. (full 2002) http://www.jneurosci.org/content/22/16/7147.long Cannabis Treatments in Obstetrics and Gynecology: A Historical Review (full - 2002) http://www.cannabis-med.org/data/pdf/2002-03-04-1_0.pdf Prenatal Marijuana Use and Neonatal Outcome. (abst 2002)
http://medical-journals.healia.com/doc/1886543/Prenatal-marijuana-use-and-neonatal-outcome
Hyperemesis Gravidarum and Clinical Cannabis: To Eat or Not to Eat? (abst - 2002) http://haworthpress.com/store/ArticleAbstract.asp?ID=18139 Maternal use of cannabis and pregnancy outcome.
(abst 2002)
Effect of maternal under-nutrition on pup body weight and hypothalamic endocannabinoid levels. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12678501 The Endocannabinoid-CB Receptor System: Importance for development and in pediatric disease (full - 2004) http://www.nel.edu/pdf_/25_12/NEL251204A01_Fride_.pdf Plasma Levels of the Endocannabinoid Anandamide in WomenA Potential Role in Pregnancy Maintenance and Labor? (full - 2004)
Aberrant cannabinoid signaling impairs oviductal transport of embryos.

(abst - 2004)
Use of anti-emetic herbs in pregnancy: women's choices, and the question of safety and efficacy (abst - 2004) http://www.ncbi.nlm.nih.gov/pubmed/14744504 Cannabinoids and the human uterus during pregnancy
(abst - 2004) (abst 2005)

552

(full - 2006)
Survey of medicinal cannabis use among childbearing women: patterns of its use in pregnancy and retroactive self-assessment of its efficacy against 'morning sickness'. (full 2006) http://safeaccess.ca/research/cannabis_nausea2006.pdf Parental marijuana use and risk of childhood acute myeloid leukaemia: a report from the Children's Cancer Group (United States and Canada). (abst 2006)
Prenatal exposure to a cannabinoid receptor agonist does not affect sensorimotor gating in rats (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16423346 More Pregnancy Highs Than Lows Oily fish makes 'babies brainier' Dreher's Jamaican Pregnancy Study Cannabis Relieves Morning Sickness (news - 2006) (news - 2006) (hemp seed - at the end) (news - 2006) (news - 2006)
http://www.thehempire.com/index.php/cannabis/news/more_pregnancy_highs_than_lows
http://www.november.org/stayinfo/breaking06/DreherStudy.html
http://ccrmg.org/journal/06spr/dreher.html#morning
The role of the endocannabinoid system in gametogenesis, implantation and early pregnancy (full - 2007)
http://humupd.oxfordjournals.org/cgi/content/full/13/5/501?maxtoshow=&hits=80&RESULTFORMAT=& fulltext=cannabinoid&searchid=1&FIRSTINDEX=960&resourcetype=HWCIT
Prevalence of gestational exposure to cannabis in a Mediterranean city by meconium analysis. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17953730 Breathe, Push, Puff? Pot Use and Pregnancy: A Review of the Literature
(news 2007)
CB2 receptors in reproduction
(full - 2008)
Volumetric MRI Study of Brain in Children With Intrauterine Exposure to Cocaine, Alcohol, Tobacco, and Marijuana (full - 2008)
http://pediatrics.aappublications.org/cgi/reprint/121/4/741?maxtoshow=&hits=80&RESULTFORMAT=&f ulltext=marihuana&searchid=1&FIRSTINDEX=400&resourcetype=HWCIT

(full - 2008)
553
(news - 2008)
Maternal tobacco, cannabis and alcohol use during pregnancy and risk of adolescent psychotic symptoms in offspring. (full - 2009)
Localisation and Function of the Endocannabinoid System in the Human Ovary (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640464/?tool=pmcentrez Marijuana/ Cannabis use in Pregnancy Dr. Melanie Dreher (article 2009)
http://patients4medicalmarijuana.wordpress.com/2009/12/20/marijuana-cannabis-use-in-pregnancy-drmelanie-dreher/
Cannabinoid/Endocannabinoid signaling impact on early pregnancy events. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/21104387 During pregnancy, recreational drug-using women stop taking ecstasy (3,4methylenedioxy-N-methylamphetamine) and reduce alcohol consumption, but continue to smoke tobacco and cannabis: initial findings from the Development and Infancy Study. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19939863 Short communication: Urinary excretion of 11-nor-9-carboxy-Delta(9)tetrahydrocannabinol in a pregnant woman following heavy, chronic cannabis use. (letter - 2009)
http://www.unboundmedicine.com/medline/ebm/record/20040136/abstract/Short_communication:_Urinary _excretion_of_11_nor_9_carboxy_Delta_9__tetrahydrocannabinol_in_a_pregnant_woman_following_hea vy_chronic_cannabis_use_
CLAIM #7: MARIJUANA USE DURING PREGNANCY HARMS THE FETUS (news - 2009) http://www.erowid.org/plants/cannabis/cannabis_myth7.shtml Maternal Marijuana use not Associated with Psychotic Symptoms , but Alcohol is (news - 2009)
The Maternal Lifestyle Study: Sleep Problems in Children with Prenatal Substance Exposure (full 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917192/?tool=pubmed Cannabinoids and Reproduction: A Lasting and Intriguing History
(full 2010)
A prospective study on intrauterine cannabis exposure and fetal blood flow. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20451334
554
Tocolytic Effect of 9-Tetrahydrocannabinol in Mice Model of Lipopolysaccharide Induced Preterm Delivery: Role of Nitric Oxide (abst - 2010)
http://rsx.sagepub.com/content/17/4/391.abstract
A common variation in the cannabinoid 1 receptor (CNR1) gene is associated with preeclampsia in the Central European population. (abst - 2010)
Characteristics of pregnant illicit drug users and associations between cannabis use and perinatal outcome in a population-based study (abst - 2010)
Pregnant Women Smoking Pot Could Reduce Infant Mortality
(news - 2010)
Pregnant women turning to cannabis for morning sickness relief risk prosecution (news - 2010)
http://stash.norml.org/pregnant-women-turning-to-cannabis-for-morning-sickness-relief-risk-prosecution
Sex difference in cell proliferation in developing rat amygdala mediated by endocannabinoids has implications for social behavior (full 2011)
Prenatal tobacco, marijuana, stimulant, and opiate exposure: outcomes and practice implications. (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188826/?tool=pubmed Commentary: Functional Neuronal CB2 Cannabinoid Receptors in the CNS. (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137183/?tool=pubmed Medical Marijuana: Can Pot Help Pregnant Women With Vomiting and Nausea? (article 2011)
Cannabinoid hyperemesis syndrome: an underreported entity causing nausea and vomiting of pregnancy. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21170540
PRIONS Nonpsychoactive cannabidiol Prevents Prion Accumulation and Protects Neurons against Prion Toxicity (full - 2007) http://www.jneurosci.org/cgi/content/full/27/36/9537
555
Recent News: Marijuana (Cannabis) May Prevent Mad Cow Disease

http://www.evilmamacow.org/marijuana-prevents-mad-cow-disease.php
(news - 2007)
Cannabidiol May be Effective in Preventing Bovine Spongiforme Enzephalopathy (Mad Cow Disease) (news - 2007) http://www.letfreedomgrow.com/articles/fr070916.htm Pot Compound Protective Against Mad Cow Disease, Other Fatal Brain Disorders, Study Says (news - 2007) http://www.norml.org/index.cfm?Group_ID=7362 Pot smoking could stop Mad Cow Disease? (news - 2008)
http://chattahbox.com/curiosity/2008/12/06/pot-smoking-could-stop-mad-cow-disease/
Alteration of the Endocannabinoid System In Mouse Brain During Prion Disease. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21195746/abstract/Alteration_of_the_Endocannabi noid_System_In_Mouse_Brain_During_Prion_Disease_
PROXIMAL MYOTONIC MYOPATHY / PROMM Marijuana for the Management of Proximal Myotonic Myopathy
(full - 2001)
PRURITIS - chronic itch Dronabinol in patients with intractable pruritus secondary to cholestatic liver disease. (abst - 2002)
Preliminary observation with dronabinol in patients with intractable pruritus secondary to cholestatic liver disease. (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/12190187 The cannabinoid agonist WIN 55, 212-2 increases nociception threshold in cholestatic rats: implications for the treatment of the pruritus of cholestasis. (abst 2003)
Histamine induced responses are attenuated by a cannabinoid receptor agonist in human skin. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12835895 Pathogenesis and treatment of pruritus in patients with cholestasis
(abst 2003)
556
Treatment of the Pruritus of Cholestasis.

(abst 2004)
Efficacy and tolerance of the cream containing structured physiological lipids with endocannabinoids in the treatment of uremic pruritus: a preliminary study. (abst - 2005)
Rational symptomatic therapy for chronic pruritus

(abst 2005)
Old drugs in new role: relieving chronic pruritus; Cannabinoid agonists, opioid receptor antagonists have attracted the attention of dermatologists (news - 2005)
Cream with endocannabinoids effective in the treatment of pruritus

(news - 2005)
Cream with endocannabinoids effective in the treatment of pruritus due to kidney disease (news - 2005) http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=207 Neurophysiological, Neuroimmunological, and Neuroendocrine Basis of Pruritus (full - 2006) http://www.nature.com/jid/journal/v126/n8/full/5700231a.html Frontiers in pruritus research: scratching the brain for more effective itch therapy (full 2006)
Topical cannabinoid agonists : An effective new possibility for treating chronic pruritus. (abst - 2006) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=196 Adjuvant treatment of atopic eczema: assessment of an emollient containing Npalmitoylethanolamine (ATOPA study). (abst - 2008)
Chronic pruritus: targets, mechanisms and future therapies.
(abst - 2008)
Endocannabinoid modulation of scratching response in an acute allergenic model: a new prospective neural therapeutic target for pruritus. (full - 2009)
557
Cannabinoid system in the skin - a possible target for future therapies in dermatology. (full - 2009) http://onlinelibrary.wiley.com/doi/10.1111/j.1600-0625.2009.00923.x/full Cannabis: Potential treatment for skin disorders? (news - 2009)
http://www.examiner.com/x-17593-NORML-Examiner~y2009m8d29-Cannabis-Potential-treatment-forskin-disorders
The Management of Chronic Pruritus in the Elderly

http://www.skintherapyletter.com/2010/15.8/2.html
(full 2010)
Is there a legitimate role for the therapeutic use of cannabinoids for symptom management in chronic kidney disease? (abst 2011)
CB1 receptors mediate rimonabant-induced pruritic responses in mice: investigation of locus of action. (abst 2011)

PSORIASIS The Endocannabinoid System in Human Keratinocytes

(full 2003)
Cannabinoids, loratadine and allopurinol as novel additions to the antipsoriatic ammunition. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/15857457 Anandamide Regulates Keratinocyte Differentiation by Inducing DNA Methylation in a CB1 Receptor-dependent Manner (full 2007) http://www.jbc.org/content/283/10/6005.full Cannabinoids inhibit human keratinocyte proliferation through a non-CB1/CB2 mechanism and have a potential therapeutic value in the treatment of psoriasis (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17157480 Marijuana Skin Cream? (news - 2007)
558
Patent application title: PHARMACOLOGICAL TREATMENT OF PSORIASIS (full 2010) http://www.faqs.org/patents/app/20080255224 Endocannabinoid signaling and epidermal differentiation. (abst 2011)
QUITTING CANNABIS - also see ADDICTION and WITHDRAWAL An Abstinence Syndrome Following Chronic Administration of Delta-9terahydrocannabinol in Rhesus Monkeys. (abst 1980)
A 12-step Treatment Approach for Marijuana (Cannabis) Dependence.
(abst 1989)
http://medical-journals.healia.com/doc/2687482/A-12-step-treatment-approach-for-marijuana-Cannabisdependence
Psychotropic Analgesic Nitrous Oxide Prevents Craving After Withdrawal for Alcohol, Cannabis and Tobacco. (abst 1994) http://www.ncbi.nlm.nih.gov/pubmed/7960461 Tobacco and Cannabis Smoking Cessation Can Lead to Intoxication with Clozapine or Olanzapine. (abst 2002)
The Time Course and Significance of Cannabis Withdrawal.
(abst 2003)
http://medical-journals.healia.com/doc/12943018/The-time-course-and-significance-of-cannabiswithdrawal
Strategies for quitting among non-treatment-seeking marijuana smokers.

(abst 2005)
Aerobic Exercise Training Reduces Cannabis Craving and Use in Non-Treatment Seeking Cannabis-Dependent Adults (full 2011)
Exercise can reduce cannabis use in persons who don't want to stop
(news 2011)
http://www.news-medical.net/news/20110304/Exercise-can-reduce-cannabis-use-in-persons-who-dontwant-to-stop.aspx
559
QUITTING OTHER DRUGS The Use of Indian Hemp in the Treatment of Chronic Chloral and Chronic Opium Poisoning (1889) http://www.onlinepot.org/medical/Dr_Tods_PDFs/s3_2.pdf Cannabis substitution . An adjunctive therapeutic tool in the treatment of alcoholism. (abst - 1970) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=86 Differential effect of cannabinol and cannabidiol on THC-induced responses during abstinence in morphine-dependent rats. (abst - 1975)
Morphine-dependent rats: blockade of precipitated abstinence by tetrahydrocannabinol. (abst 1975) http://www.ncbi.nlm.nih.gov/pubmed/1167428 Effect of some cannabinoids on naloxone-precipitated abstinence in morphine-dependent mice. (abst 1976)
Inhibition of naloxone-induced withdrawal in morphine dependent mice by 1-transdelta9-tetrahydrocannabinol. (abst 1976) http://www.ncbi.nlm.nih.gov/pubmed/944134 Time course of the effects of naturally occurring cannabinoids on morphine abstinence syndrome. (abst 1978) http://www.ncbi.nlm.nih.gov/pubmed/564515 The quasi-morphine withdrawal syndrome: effect of cannabinol, cannabidiol and tetrahydrocannabinol. (abst - 1985)
Marijuana use and treatment outcome among opioid-dependent patients.

(abst 1998)
Therapeutic use of cannabis by crack addicts in Brazil.
(full - 1999)
http://science.iowamedicalmarijuana.org/pdfs/addiction/Labigalini%20Therapeutic%20Cannabis%20Crack %20Brazil%20J%20Psychoact%20Drugs%201999.pdf
Go clean with spliffs
(news - 2001) (news - 2001)
http://www.newscientist.com/article/mg17223123.800-go-clean-with-spliffs.html
Cannabinoids vs. Cocaine
Crack heads and roots daughters: The therapeutic use of cannabis in Jamaica (cocaine) (abst - 2002)
560
Does Cannabis Use Predict Poor Outcome for Heroin-Dependent Patients on Maintenance Treatment? A Review of Past Findings, and More Evidence Against (full 2003) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943839/ Modulation of oral morphine antinociceptive tolerance and naloxone-precipitated withdrawal signs by oral Delta 9-tetrahydrocannabinol. (full 2003)
Does Cannabis Use Predict Poor Outcome for Heroin-dependent Patients on Maintenance Treatment? Past Findings and More Evidence Against. (abst 2003)
http://medical-journals.healia.com/doc/12603227/Does-cannabis-use-predict-poor-outcome-for-heroindependent-patients-on-maintenance-treatment-Past-findings-and-more-evidence-against
Cannabis as a Substitute for Alcohol
(news - 2003)
http://ccrmg.org/journal/03sum/substitutealcohol.html
Delta9-tetrahydrocannabinol decreases somatic and motivational manifestations of nicotine withdrawal in mice. (abst - 2004)
Comparison of Cannabidiol, Antioxidants, and Diuretics in Reversing Binge EthanolInduced Neurotoxicity (full - 2005) http://jpet.aspetjournals.org/content/314/2/780.full Role of cannabinoid receptors in alcohol abuse
(news - 2005)
Subchronic cannabinoid agonist (WIN 55,212-2) treatment during cocaine abstinence alters subsequent cocaine seeking behavior. (full - 2007)
Modulation of the endocannabinoid system: therapeutic potential against cocaine dependence. (full - 2007)
561
Curing Addiction With Cannabis Medicines? Cannabis-based Drugs can help you quit Smoking
(news - 2008) (news - 2008)
http://www.healthjockey.com/2008/03/11/cannabis-based-drugs-can-help-you-quit-smoking/
Intermittent marijuana use is associated with improved retention in naltrexone treatment for opiate-dependence. (full - 2009)
Cannabis as a substitute for alcohol and other drugs.
(full - 2009)
Effects of the cannabinoid CB1 receptor antagonist AM 251 on the reinstatement of nicotine-conditioned place preference by drug priming in rats. (full- 2009)
Interaction of the cannabinoid and opioid systems in the modulation of nociception. (abst - 2009)
Is Cannabis the Answer to Booze Britain's Problems?

(news - 2009) (news - 2009) (full - 2010)
Cannabis as a substitute for heavy alcohol usage?
http://www.news-medical.net/news/20091201/Cannabis-as-a-substitute-for-heavy-alcohol-usage.aspx
Medical marijuana users in substance abuse treatment.
Oaklanders Quitting Oxycontin with Cannabis
(news - 2010)
http://www.eastbayexpress.com/LegalizationNation/archives/2010/04/22/oaklanders-quitting-oxycontinwith-cannabis
Marijuana To Control Alcohol Abuse Marijuana could be an exit drug
(news - 2010) (news - 2010)
http://psychcentral.com/news/2009/12/01/marijuana-to-control-alcohol-abuse/9863.html
http://newmexicoindependent.com/52915/marijuana-could-be-an-exit-drug
562
Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition. (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227620/?tool=pubmed The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine-induced dopamine elevations in the nucleus accumbens shell in rats (abst 2011)
Brain cannabinoid CB2 receptors modulate cocaine's actions in mice

(abst 2011)
The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine-induced dopamine elevations in the nucleus accumbens shell in rats. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21557729 Study: Marijuana compound helps mitigate cocaine addiction in mice (news 2011)
http://www.rawstory.com/rs/2011/07/26/study-marijuana-compound-helps-mitigate-cocaine-addiction-inmice/
Stimulation Of Marijuana Receptor Reduces Cocaine Consumption, Study Says (news 2011) http://norml.org/index.cfm?Group_ID=8639 Why Medical Marijuana Laws Reduce Traffic Deaths Medical marijuana turns former soldier's life around (news - 2011) (news 2011)
RADIATION-INDUCED NAUSEA Randomised Clinical Trial of Levonantradol and Chlorpromazine in the Prevention of Radiotherapy-induced Vomiting. (abst - 1982)
563
A double-blind randomised cross-over comparison of nabilone and metoclopramide in the control of radiation-induced nausea. (abst - 1987)
Receptor mechanism and antiemetic activity of structurally-diverse cannabinoids against radiation-induced emesis in the least shrew. (full - 2007)
RADIATION SICKNESS Regulation of hematopoietic stem cell trafficking and mobilization by the endocannabinoid system. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22074629
REFLEX SYMPATHETIC DYSTROPHY DEA Raids Aurora Medical Marijuana User

http://www.freecolorado.com/2004/07/danaraid.html
(news/ anecdotal 2004)
Medi-Cal pays pot-related expenses
(news 2007)
http://www.pressdemocrat.com/article/20070707/NEWS/707070324?Title=Medi-Cal-pays-pot-relatedexpenses
RSD Patient Gets Relief Through Medical Marijuana
(news - 2009)
http://www.disaboom.com/reflex-sympathetic-dystrophy-syndrome-rsd/rsd-patient-gets-relief-throughmedical-marijuana
An Opiate Controlled Population by Ryan Harshbarger
(news/ anecdotal- 2009)
http://www.bakedlife.com/2009/09/opiate-controlled-population-by-ryan.html
Control of bone remodeling by nervous system. Nervous system and bone (abst 2010)
RESTLESS LEG SYNDROME Marijuana & Restless Leg Syndrome (news - no date)
http://www.ehow.com/about_5380787_marijuana-restless-leg-syndrome.html
Restless Leg Syndrome: Medical Marijuana Patients Say it Works (news - 2007)
http://www.salem-news.com/articles/august182007/leveque_med_restless_81807.php
564
Restless Leg Syndrome
(news/anecdotal- 2007)
RETINITIS PIGMENTOSA Smoking dope restored my sight (news - 1998)

Cannabis improves night vision: a case study of dark adaptometry and scotopic sensitivity in kif smokers of the Rif mountains of northern Morocco (full - 2004)
When spliff gets in your eyes...
(news 2004)
http://www.guardian.co.uk/science/2004/jul/07/sciencenews.research
RIMONABANT/ ACOMPLIA/ SR141716/ SR1 a CB1 & CB2 antagonist The cannabinoid CB1 receptor antagonist SR 141716A reverses the antiemetic and motor depressant actions of WIN 55, 212-2 (abst 2001) http://pharmgkb.org/pmid/11698062 Cannabinoid receptor type 1 modulates excitatory and inhibitory neurotransmission in mouse colon (full 2003)
Activation of the Peripheral Endocannabinoid System in Human Obesity

(full - 2005)
Enhancing Cannabinoid Neurotransmission Augments the Extinction of Conditioned Fear (full - 2005) http://www.nature.com/npp/journal/v30/n3/full/1300655a.html
565
The Cannabinoid Cb1 Receptor Antagonist Rimonabant Attenuates the Hypotensive Effect of Smoked Marijuana in Male Smokers. (full 2006)
(full - 2006)
Anxiolytic-like properties of the anandamide transport inhibitor AM404. (abst 2006)

Lack of tolerance to the suppressing effect of rimonabant on chocolate intake in rats. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16491428 Big Pharma's Strange Holy Grail: Cannabis Without Euphoria?
(news - 2006)
Single and multiple doses of rimonabant antagonize acute effects of smoked cannabis in male cannabis users. (full - 2007)
Rimonabant (SR141716) exerts anti-proliferative and immunomodulatory effects in human peripheral blood mononuclear cells ( full - 2007)
Report in Lancet Links Rimonabant to 'Severe Adverse Psychiatric Events' (news - 2007) http://www.rimonabantreport.com/News/news-111707.htm Delay in Approval of Diet Pill Rimonabant in U.S. Tied to 'Psychiatric Adverse Effects' (news - 2007) http://www.rimonabantreport.com/News/news-061107.htm Study: Rimonabant Weight Loss Modest and Side-Effects Are Concern
http://www.rimonabantreport.com/News/news-111507.htm
(news - 2007)
European watchdog warns about dangers of Acomplia

(news - 2007) (news - 2007)
Three Long-Term Diet Pills Show Poor Performance, Study Suggests

566
FDA Advisory Panel Rejects Obesity Drug
(news - 2007)
http://firstwatch.jwatch.org/cgi/content/full/2007/615/2?maxtoshow=&hits=80&RESULTFORMAT=&full text=cannabinoid&searchid=1&FIRSTINDEX=2800&resourcetype=HWCIT
Study: Acomplia (Rimonabant) May Increase Risk of Colorectal Cancer

http://www.rimonabantreport.com/News/news-080208.htm
(news - 2008)
Rimonabant doesn't reduce heart risk
(news - 2008) (news - 2008)
http://www.healthandage.com/Rimonabant-doesnt-reduce-heart-risk
Caution Urged With New Anti-Obesity Drug In Kids

Regulators Call for Withdrawal of Acomplia (Rimonabant) from European Market (news - 2008) http://www.rimonabantreport.com/News/news-102408.htm The psychiatric side-effects of rimonabant. (full 2009)
Evaluation of Prevalent Phytocannabinoids in the Acetic Acid Model of Visceral Nociception (full 2009)
Systematic review and meta-analysis on the adverse events of rimonabant treatment: Considerations for its potential use in hepatology (full - 2009)
http://www.biomedcentral.com/1471-230X/9/75

(abst - 2009)

(full 2010)
567
The Effects of Rimonabant on Brown Adipose Tissue in Rat: Implications for Energy Expenditure (full - 2010) http://www.nature.com/oby/journal/v17/n2/full/oby2008509a.html The Endocannabinoid System Tonically Regulates Inhibitory Transmission and Depresses the Effect of Ethanol in Central Amygdala (abst - 2010)
Anxiety-like effects of SR141716-precipitated delta9-tetrahydrocannabinol withdrawal in mice in the elevated plus-maze. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20363293/abstract/Anxiety_like_effects_of_SR141 716_precipitated_delta9_tetrahydrocannabinol_withdrawal_in_mice_in_the_elevated_plus_maze_
Reduced neural response to reward following 7 days treatment with the cannabinoid CB1 antagonist rimonabant in healthy volunteers (abst 2010)
Risk of suicide spurs rimonabant trial to end.
(news 2010) (full 2011)
http://www.thefreelibrary.com/Risk+of+suicide+spurs+rimonabant+trial+to+end.-a0238838571

Psychiatric adverse effects of rimonobant in adults with Prader Willi syndrome. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/20965292 The identification of rimonabant polymorphs, sibutramine and analogues of both in counterfeit Acomplia bought on the internet. (abst 2011)
Pro-epileptic effects of the cannabinoid receptor antagonist SR141716 in a model of audiogenic epilepsy. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21733658 Pharmacological activation/inhibition of the cannabinoid system affects alcohol withdrawal-induced neuronal hypersensitivity to excitotoxic insults. (abst 2011)
Antagonist-elicited cannabis withdrawal in humans.

(abst 2011)
568
Effects of the cannabinoid antagonist SR 141716 on sexual and motor behavior in receptive female rats. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21848907 CB(1) -independent mechanisms of (9) -THCV, AM251 and SR141716 (rimonabant). (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21740450 CB1 receptors mediate rimonabant-induced pruritic responses in mice: investigation of locus of action. (abst 2011)
CB1 cannabinoid receptor mediates glucocorticoid effects on hormone secretion induced by volume and osmotic changes. (abst 2011)

(news 2011)
The inverse agonist effect of rimonabant on G protein activation is not mediated by the cannabinoid CB1 receptor: Evidence from postmortem human brain. (abst 2012)
Rimonabant reduces the essential value of food in the genetically obese Zucker rat: An exponential demand analysis. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/22019829 Extinction learning of rewards in the rat: is there a role for CB1 receptors? (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/21519986
R(+)-METHANANANDAMIDE synthetic, Anandamide analog Cannabinoids might reduce spasticity in multiple sclerosis (full - 2000)
Endogenous cannabinoids improve myocardial resistance to arrhythmogenic effects of coronary occlusion and reperfusion: a possible mechanism. (abst - 2002)
569

(full 2003)
Cannabinoid Receptor-Mediated Apoptosis Induced by R(+)-Methanandamide and Win55,212-2 Is Associated with Ceramide Accumulation and p38 Activation in Mantle Cell Lymphoma (full - 2006) http://molpharm.aspetjournals.org/content/70/5/1612.full R(+)-methanandamide elicits a cyclooxygenase-2-dependent mitochondrial apoptosis signaling pathway in human neuroglioma cells. (abst 2006)
http://www.springerlink.com/content/l403431l1728x733/

(full - 2008)
Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)Methanandamide and JWH-015: Involvement of CB2 (full - 2009)
Potentiation of cannabinoid-induced cytotoxicity in mantle cell lymphoma through modulation of ceramide metabolism. (full - 2009)
http://mcr.aacrjournals.org/content/7/7/1086.long
Cannabinoid Receptor Activation Protects Coronary Endothelium Against Reperfusion Induced Intercellular Gap Formation in a Cellular Model of Ischemia and Reperfusion (abst - 2009)
http://circ.ahajournals.org/cgi/content/meeting_abstract/120/18_MeetingAbstracts/S1072c?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=720& resourcetype=HWCIT
The cannabinoid R+ methanandamide induces IL-6 secretion by prostate cancer PC3 cells. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19908944 R(+)-methanandamide-induced apoptosis of human cervical carcinoma cells involves a cyclooxygenase-2-dependent pathway. (abst 2009)
Cannabis chemicals may help fight prostate cancer
(news - 2010)
570
Effects of Cannabinoid Agonists on Sheep Sphincter of Oddi in vitro.

(abst 2011)
RWJ 400065 - synthetic cannabinoid Control of spasticity in a multiple sclerosis model is mediated by CB1, not CB2, cannabinoid receptors. (full - 2007)
SAFETY AS A MEDICINE THE RELATIVE ACTIVITY OF VARIOUS PURIFIED PRODUCTS OBTAINED FROM AMERICAN GROWN HASHISH (abst - 1938)
STUDIES ON THE PHARMACOLOGY AND ACUTE TOXICITY OF COMPOUNDS WITH MARIHUANA ACTIVITY (abst - 1946)
Allergy to Marihuana
(abst - 1971)
http://www.annals.org/content/75/4/571.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=ca nnabis&searchid=1&FIRSTINDEX=1920&resourcetype=HWCIT
Cognition and Long-Term Use of Ganja (Cannabis)

(full - 1981)
http://www.ukcia.org/research/merck.htm
Excerpt from the Merck Manual

(excerpt- 1987)
THREE THINGS MARIJUANA DOESN'T DO
(news - 1992)
Health care use by frequent marijuana smokers who do not smoke tobacco. (full - 1993) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1311782/pdf/westjmed00082-0044.pdf Proven: Cannabis is safe medicine (news - 1996) (abst 2002)
http://www.ukcia.org/research/safe-medicine.htm

571
The good and the bad effects of () trans-delta-9-tetrahydrocannabinol (9-THC) on humans (abst - 2004)
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TCS-4CSG2C42&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlV ersion=0&_userid=10&md5=99df29b0ce94c395c01f5aad8825d28b
Adverse effects of medical cannabinoids: a systematic review

(full - 2008)
Merck Manual - Marijuana (Cannabis) How Safe Are Medical Cannabinoids?
(excerpt - 2008) (news 2008)
Claims Linking Health Problems And The Strength Of Cannabis May Be Exaggerated (news - 2008)
Medical use of cannabinoids does not cause an increase in serious adverse health effects (news - 2008) http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=272 Report: Marijuana Less Harmful than Alcohol or Tobacco
http://www.drugfree.org/join-together/other/report-marijuana-less
(news - 2008) (news - 2008)
Medicines derived from cannabis: A review of adverse events

Alcohol and cannabis use as risk factors for injury - a case-crossover analysis in a Swiss hospital emergency department (full - 2009)
Deaths from Marijuana v. 17 FDA-Approved Drugs (Jan. 1, 1997 to June 30, 2005) (report - 2009) http://medicalmarijuana.procon.org/view.resource.php?resourceID=145 Harms associated with psychoactive substances: findings of the UKNational Drug Survey (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19939875/full_citation/Harms_associated_with_ps ychoactive_substances:_findings_of_the_UK_National_Drug_Survey_
Health Risks of Marijuana Still Not Nailed Down

http://www.medpagetoday.com/Psychiatry/Addictions/16456
(news - 2009) (news 2009)
Four percent of adults worldwide using cannabis
http://www.independent.co.uk/life-style/health-and-families/health-news/four-percent-of-adults-worldwideusing-cannabis-1804190.html
572
Marijuana-Related Health Costs Minimal Compared To Those Of Alcohol, Tobacco (news - 2009) http://www.norml.org/index.cfm?Group_ID=8022 The FDA has written documentation that patients can overdose on Marinol and that it can be lethal (news - 2009)
Information for Health Care Professionals (revised) - Overdose/Toxicity (Health Canada) (full - 2010)
Harms associated with psychoactive substances: findings of the UK National Drug Survey (abst - 2010) http://jop.sagepub.com/cgi/content/abstract/24/2/147?rss=1 An index of fatal toxicity for drugs of misuse. (full - 2010)
http://www.scribd.com/doc/41349905/Alcohol-Lancet-2010
Alcohol 'Most Harmful Drug', According to Multicriteria Analysis (news - 2010) http://www.sciencedaily.com/releases/2010/11/101101162138.htm Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent. (abst- 2011)
http://www.unboundmedicine.com/medline/ebm/record/22129319/abstract/Safety_and_Side_Effects_of_C annabidiol_a_Cannabis_sativa_Constituent_
Medical marijuana not a threat to workplace safety, study finds Is Pot Good For You? (news 2011) (full 2012)
(news 2011)
http://washingtonindependent.com/110759/medical-marijuana-not-a-threat-to-workplace-safety-study-finds
Prescribing Cannabis for Harm Reduction.
SAFETY- ADULTERANTS/ CONTAMINANTS Examination of fungal growth and aflatoxin production on marihuana.
(abst 1977)
An effect of paraquat on the lungs of rabbits. Its implications in smoking contaminated marihuana. (full - 1978) http://chestjournal.chestpubs.org/content/74/4/418.long Paraquat goes to pot. (full - 1978)
Paraquat and marihuana. Assessing the hazard.

(full - 1978)
573
Detection and analysis of paraquat in confiscated marijuana samples. (abst 1978)

Allergic bronchopulmonary aspergillosis associated with smoking moldy marihuana. (full - 1978) http://chestjournal.chestpubs.org/content/73/6/871.long Paraquat and marijuana: epidemiologic risk assessment. Marijuana smoking and fungal sensitization.
(full -1983)
(abst - 1983)
Fatal aspergillosis associated with smoking contaminated marijuana, in a marrow transplant recipient. (full - 1988) http://chestjournal.chestpubs.org/content/94/2/432.long Microbiological contaminants of marijuana
(full - 1994)
Successfully treated invasive pulmonary aspergillosis associated with smoking marijuana in a renal transplant recipient. (abst - 1996) http://www.ncbi.nlm.nih.gov/pubmed/8685958 Dust in the wind: the growing use of embalming fluid among youth in Hartford, CT. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/16040367 When the drug of choice is a drug of confusion: embalming fluid use in inner city Hartford, CT. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/16275635 Beliefs and social norms about cigarettes or marijuana sticks laced with embalming fluid and phencyclidine (PCP): why youth use "fry". (abst 2005)
An evaluation of the quality of medicinal grade cannabis in the Netherlands (full - 2006) http://www.cannabis-med.org/english/journal/en_2006_01_1.pdf Adulteration of cannabis with tobacco, calamus, and other cholinergic compounds (full - 2008) http://www.cannabis-med.org/english/journal/en_2008_04_2.pdf Invasive Pulmonary Aspergillosis Associated With Marijuana Use in a Man With Colorectal Cancer (full - 2008)
http://jco.ascopubs.org/cgi/content/full/26/13/2214?maxtoshow=&hits=80&RESULTFORMAT=&fulltext =cannabis&searchid=1&FIRSTINDEX=3520&resourcetype=HWCIT
The use of fry (embalming fluid and PCP-laced cigarettes or marijuana sticks) among crack cocaine smokers (abst - 2008)
http://www.unboundmedicine.com/medline/ebm/record/19157045/abstract/The_use_of_fry__embalming_f luid_and_PCP_laced_cigarettes_or_marijuana_sticks__among_crack_cocaine_smokers_
574
Ammonia release from heated 'street' cannabis leaf and its potential toxic effects on cannabis users. (abst - 2008)
http://www.unboundmedicine.com/medline/ebm/record/18705690/abstract/Ammonia_release_from_heated _%27street%27_cannabis_leaf_and_its_potential_toxic_effects_on_cannabis_users_
Neuropsychological effects of formaldehyde use.

(abst - 2008) (abst - 2008)
Cannabis potency and contamination: a review of the literature.

Lead poisoning due to adulterated marijuana in Leipzig. Smoke Pot, Get Lead Poisoning? (Germany/Europe)
(full - 2008) (news - 2008) (abst 2009)
http://www.webmd.com/news/20080409/smoke-pot-get-lead-poisoning
Respiratory consequences of inhalation of adulterated cannabis

Medical marijuana tested for toxins and impurities

http://www.wmbfnews.com/Global/story.asp?S=12340335
(news - 2010) (full 2011)
Too many mouldy joints - marijuana and chronic pulmonary aspergillosis.

SATIVEX / NABIXIMOLS - a cannabis extract spray Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis (full - 2005)
Sativex: Fact Sheet
(full - 2005)
http://www.bayer.ca/files/sativex_fs_fd_091289_e.pdf
(letter - 2005)
http://www.bayer.ca/files/sativex_dhcpl_lapds_091289_e.pdf
Sativex produced significant improvements in a subjective measure of spasticity (abst - 2005) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=170 Cannabis-based medicinal extract (Sativex) produced significant improvements in a subjective measure of spasticity which were maintained on long-term treatment with no evidence of tolerance. (abst - 2005)
575
Conditional okay for cannabis prescription drug Cannabis-Based Drug Relieves Arthritis Pain
(news - 2005) (news - 2005)
http://www.medpagetoday.com/Rheumatology/Arthritis/2097
Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis (full - 2006)
http://rheumatology.oxfordjournals.org/cgi/content/full/45/1/50?maxtoshow=&hitqs=80&RESULTFORM AT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=2240&resourcetype=HWCIT
The use of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis (letter - 2006)
Randomised controlled study of cannabis-based medicine (Sativex) in patients suffering from multiple sclerosis associated detrusor overactivity (abst - 2006)
Sativex in patients with symptoms of spasticity due to multiple sclerosis (abst - 2006)
SAFETY AND TOLERABILITY OF LONG-TERM TREATMENT WITH A CANNABIS-BASED MEDICINE (SATIVEX) IN PATIENTS WITH RHEUMATOID ARTHRITIS (abst - 2006)
http://eular.bmj.com/cgi/content/abstract/65/Suppl_2/498a?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1840 &resourcetype=HWCIT
Combined cannabinoid therapy via an oromucosal spray
(abst 2006)
http://journals.prous.com/journals/servlet/xmlxsl/pk_journals.xml_summaryn_pr?p_JournalId=4&p_RefId =1021517
Sativex showed positive effects in 65 per cent of patients with chronic diseases (news - 2006)
Sativex: Fact Sheet
(full - 2007) (letter - 2007)
http://www.bayer.ca/files/sativex_fs_fd_109461_e%20_GW_.pdf
http://www.bayer.ca/files/sativex_dhcpl_lapds_109461_e%20_GW_-2.pdf
576
Oromucosal delta9-tetrahydrocannabinol/cannabidiol for neuropathic pain associated with multiple sclerosis: an uncontrolled, open-label, 2-year extension trial. (abst 2007)
Cannabis; adverse effects from an oromucosal spray.

http://www.nature.com/bdj/journal/v203/n6/abs/bdj.2007.749.html
(abst - 2007)
Cannabis, pain, and sleep: lessons from therapeutic clinical trials of Sativex, a cannabisbased medicine. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17712817 Symptomatic treatment of multiple sclerosis using cannabinoids: recent advances. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17868014 Sativex successfully treats neuropathic pain characterised by allodynia: A randomised, double-blind, placebo-controlled clinical trial (abst - 2007)
Cannabinoids Associated With "More Restful Sleep," Study Says

(news - 2007)
Sativex: Drug Monograph
(monograph - 2008) (full - 2008) (full - 2008)
http://www.bayer.ca/files/SATIVEX-PM-ENG-18DEC2008-119950.pdf
Sativex: Consumer Information
http://www.bayer.ca/files/SATIVEX-PM-ENG-PT3-18DEC2008-119950.pdf
Emerging strategies for exploiting cannabinoid receptor agonists as medicines. (full 2009)
Summary of Product Characteristics- Sativex Oralmucosal Spray

http://www.gwpharm.com/uploads/spc-doc.pdf
(full 2010)
Randomized controlled trial of Sativex to treat detrusor overactivity in multiple sclerosis. (abst 2010) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=314 Abuse potential and psychoactive effects of -9-tetrahydrocannabinol and cannabidiol oromucosal spray (Sativex), a new cannabinoid medicine. (abst 2011)
577
Subjective and physiological effects after controlled Sativex and oral THC administration. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21289620 Neuroprotective effects of phytocannabinoid-based medicines in experimental models of Huntington's disease. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21674569 A randomized, double-blind, placebo-controlled, crossover study to evaluate the subjective abuse potential and cognitive effects of nabiximols oromucosal spray in subjects with a history of recreational cannabis use. (abst 2011)
Plasma cannabinoid pharmacokinetics following controlled oral delta9tetrahydrocannabinol and oromucosal cannabis extract administration
(abst 2011)
Is Pot Good For You?
(news 2011)
SCHIZOPHRENIA/ MENTAL DISORDERS radical notion (letter - 1974)

http://schizophreniabulletin.oxfordjournals.org/cgi/reprint/1/11/16a?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid=1&FIRSTINDEX=1040&res ourcetype=HWCIT
Study Shows Long Term Marijuana Users Healthy

http://www.erowid.org/plants/cannabis/cannabis_science3.shtml
(news - 1994)
Association study of a cannabinoid receptor gene (CNR1) polymorphism and schizophrenia (abst 2000) http://pharmgkb.org/pmid/11204352
578
Are Cannabinoid Receptor Knockout Mice Animal Models for Schizophrenia? (abst -2000) http://www.medical-hypotheses.com/article/S0306-9877%2800%2991261-1/abstract Cannabis Use is Not Associated with the Development of Psychosis in an 'ultra' High-risk Group. (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/12406123 Tobacco and Cannabis Smoking Cessation Can Lead to Intoxication with Clozapine or Olanzapine. (abst 2002)
Recipe For Trouble
(anecdotal/ news - 2002) (news - 2002)
Cannabis may treat psychiatric disorders Cannabis and the brain. (full - 2003)
http://findarticles.com/p/articles/mi_hb5255/is_2002_August_5/ai_n28936175/?tag=content;col1
Haloperidol, but not clozapine, produces dramatic catalepsy in delta9-THC-treated rats: possible clinical implications. (full - 2003)
Cannabis as a psychotropic medication

(letter - 2004)
Lower Negative Symptom Scores Among Cannabis-dependent Patients with Schizophrenia-spectrum Disorders: Preliminary Evidence from an African American First-episode Sample. (abst 2004)
http://www.schres-journal.com/article/S0920-9964%2804%2900035-0/abstract
Aetiology - Review: current evidence does not show a strong causal relation between the use of cannabis in young people and psychosocial harm (abst - 2004)
http://www.library.nhs.uk/mentalHealth/ViewResource.aspx?resID=224106&tabID=289
How our brains fend off madness, we produce a cannabis like substance
(news 2004)
Cannabis does not induce schizophrenia, Dutch scientists say

(news - 2004)
Symptoms of schizotypy precede cannabis use.
(full - 2005)
http://socialsciences.people.hawaii.edu/publications_lib/Cannabis%20and%20SPD.pdf
Cannabidiol as an antipsychotic. A double-blind, controlled clinical trial on cannabidiol vs. amisulpride in acute schizophrenia. (abst - 2005) http://www.cannabismed.org/studies/ww_en_db_study_show.php?s_id=171
579
Cannabis and schizophrenia link blurs further
(news - 2005)
http://www.newscientist.com/channel/health/mg18624953.800-cannabis-and-schizophrenia-link-blursfurther.html

(news - 2005) (full - 2006)
Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug.

The Mental Health Risks of Adolescent Cannabis Use Cannabis and psychosis (letter - 2006)
(full - 2006)
An Experimental Study of Catechol-O-Methyltransferase Val(158)Met Moderation of Delta-9-Tetrahydrocannabinol-Induced Effects on Psychosis and Cognition. (abst - 2006)
http://www.unboundmedicine.com/medline/ebm/record/16936704/abstract/An_Experimental_Study_of_Ca techol_O_Methyltransferase_Val_158_Met_Moderation_of_Delta_9_Tetrahydrocannabinol_Induced_Effe cts_on_Psychosis_and_Cognition
Increased cannabinoid receptor density in the posterior cingulate cortex in schizophrenia. (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16710682 Cannabis use does not cause schizophrenia (news - 2006) (news - 2006)
http://www.health.am/psy/more/cannabis_use_does_not_cause_schizophrenia/
No Increased Schizophrenia Risk With Use Of Cannabis
http://www.thehempire.com/index.php/cannabis/news/no_increased_schizophrenia_risk_with_use_of_cann abis
Cannabis is a First-Line Treatment for Childhood Mental Disorders (news - 2006)

http://www.counterpunch.org/mikuriya07082006.html
Reefer Madness Refuted
(letter - 2007)
http://www.cmaj.ca/cgi/eletters/177/8/988#16873
A Comparison of Symptoms and Family History in Schizophrenia with and Without Prior Cannabis Use: Implications for the Concept of Cannabis Psychosis. (abst 2007)
http://www.schres-journal.com/article/S0920-9964%2807%2900150-8/abstract
Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients: Impact of cannabis use. (abst - 2007)
http://www.unboundmedicine.com/medline/ebm/record/17566707/abstract/Anandamide_levels_in_cerebro spinal_fluid_of_first_episode_schizophrenic_patients:_Impact_of_cannabis_use
580
Cannabinoids and psychosis. (abst - 2007)

Effects of cannabidiol on schizophrenia-like symptoms in people who use cannabis (full - 2008)
http://bjp.rcpsych.org/cgi/content/full/192/4/306?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=ca nnabinoid&searchid=1&FIRSTINDEX=1200&resourcetype=HWCIT
The effects of cannabis abuse on the symptoms of schizophrenia: patient perspectives. (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/18666905 Maternal tobacco, cannabis and alcohol use during pregnancy and risk of adolescent psychotic symptoms in offspring. (full - 2009)
Cannabis and suicide: longitudinal study.

http://bjp.rcpsych.org/content/195/6/492.long
(full - 2009) (abst - 2009)
Parasitic brain infection, endocannabinoids, and schizophrenia.
http://www.unboundmedicine.com/medline/ebm/record/18995970/abstract/Parasitic_brain_infection_endoc annabinoids_and_schizophrenia_
The role of cannabis in cognitive functioning of patients with schizophrenia. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19326102/abstract/The_role_of_cannabis_in_cogni tive_functioning_of_patients_with_schizophrenia_
Cannabis use and deliberate self-harm in adolescence: a comparative analysis of associations in England and Norway. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19813111/abstract/Cannabis_use_and_deliberate_s elf_harm_in_adolescence:_a_comparative_analysis_of_associations_in_England_and_Norway_
Opposite relationships between cannabis use and neurocognitive functioning in bipolar disorder and schizophrenia. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19891810/full_citation/Opposite_relationships_bet ween_cannabis_use_and_neurocognitive_functioning_in_bipolar_disorder_and_schizophrenia_
Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania (abst 2009)
http://jop.sagepub.com/content/25/2/274.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=c annabinoid&searchid=1&FIRSTINDEX=320&sortspec=date&resourcetype=HWCIT
Synthetic delta-9-tetrahydrocannabinol (dronabinol) can improve the symptoms of schizophrenia. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19440079/abstract/Synthetic_delta_9_tetrahydroca nnabinol__dronabinol__can_improve_the_symptoms_of_schizophrenia_
581
Can recreational doses of THC produce significant dopamine release in the human striatum? (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19539765/full_citation/Can_recreational_doses_of _THC_produce_significant_dopamine_release_in_the_human_striatum
If cannabis caused schizophrenia-how many cannabis users may need to be prevented in order to prevent one case of schizophrenia? England and Wales calculations. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19832786/full_citation/If_cannabis_caused_schizo phrenia_how_many_cannabis_users_may_need_to_be_prevented_in_order_to_prevent_one_case_of_schiz ophrenia_England_and_Wales_calculations_
Minimal Relationship Between Cannabis And Schizophrenia Or Psychosis, Suggested By New Study (news - 2009) http://www.sciencedaily.com/releases/2009/10/091022101538.htm Science: The development of the number of new schizophrenia cases in the UK does not support the hypothesis that cannabis use increases schizophrenia risk (news 2009)
Schizophrenia link to cannabis denied
(news - 2009)
http://www.thisisstaffordshire.co.uk/news/Schizophrenia-link-cannabis-denied/article-1288926detail/article.html
New study suggests minimal relationship between cannabis and schizophrenia or psychosis (news 2009) http://www.physorg.com/news175425054.html THC can improve symptoms of schizophrenia (news 2009)
Maternal Marijuana use not Associated with Psychotic Symptoms , but Alcohol is. (news - 2009)
Endocannabinoids and Schizophrenia

(full 2010)
Do patients think cannabis causes schizophrenia? - A qualitative study on the causal beliefs of cannabis using patients with schizophrenia (full - 2010)
Reasons for illicit drug use in people with schizophrenia: Qualitative study (full 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999587/?tool=pubmed Are cannabis use disorders associated with an earlier age at onset of psychosis? A study in first episode schizophrenia. (full 2010)
582

(full 2010)
A common polymorphism in the cannabinoid receptor 1 (CNR1) gene is associated with antipsychotic-induced weight gain in Schizophrenia. (full 2010)
CannabinoidDopamine Interaction in the Pathophysiology and Treatment of CNS Disorders (full 2010) http://onlinelibrary.wiley.com/doi/10.1111/j.1755-5949.2010.00144.x/full Brain cannabinoid CB2 receptor in schizophrenia.
(abst 2010)
Cannabinoid self-administration attenuates PCP-induced schizophrenia-like symptoms in adult rats. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19854030 Does intravenous {triangleup}9-tetrahydrocannabinol increase dopamine release? A SPET study. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed?term=20851843 The Impact of Cannabis Use on Cognitive Functioning in Patients With Schizophrenia: A Meta-analysis of Existing Findings and New Data in a First-Episode Sample. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20660494 Attraction to cannabis among men with schizophrenia: a phenomenological study. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20420097 Tardive Dystonia and the Use of Cannabis (letter - 2010)
http://www.turkpsikiyatri.com/en/default.aspx?modul=article&id=749
Oral THC Reduces Aggressive Behavior In Patients With Refractory Psychosis, Study Says (news - 2010) http://www.norml.org/index.cfm?Group_ID=8419 Risk of suicide spurs rimonabant trial to end. (news 2010)
http://www.thefreelibrary.com/Risk+of+suicide+spurs+rimonabant+trial+to+end.-a0238838571
Deletion of CB2 Cannabinoid Receptor Induces Schizophrenia-Related Behaviors in Mice (full 2011) http://www.nature.com/npp/journal/v36/n7/full/npp201134a.html Cannabis use predicts shorter duration of untreated psychosis and lower levels of negative symptoms in first-episode psychosis: a South African study. (full 2011)
http://www.ajop.co.za/Journals/November2010/Original%20articles/Cannabis%20use.pdf
583
Cannabinoids for the Treatment of Schizophrenia? A Balanced Neurochemical Framework for Both Adverse and Therapeutic Effects of Cannabis Use (full 2011) http://www.hindawi.com/journals/sprt/2011/501726 / Psychopharmacological comparison of schizophrenia spectrum disorder with and without cannabis dependency. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21087649 Synthetic cannabinoid JWH-018 and psychosis: An explorative study. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21316162/abstract/Synthetic_cannabinoid_JWH_0 18_and_psychosis:_An_explorative_study_
Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions. (abst 2011) http://www.nature.com/neuro/journal/v14/n3/full/nn.2736.html Endocannabinoid system dysfunction in mood and related disorders.
(abst 2011)
Cannabis with high cannabidiol content is associated with fewer psychotic experiences. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21592732 Sub-chronic impact of cannabinoids in street cannabis on cognition, psychotic-like symptoms and psychological well-being. (abst 2011)
The Dopamine and Cannabinoid Interaction in the Modulation of Emotions and Cognition: Assessing the Role of Cannabinoid CB1 Receptor in Neurons Expressing Dopamine D1 Receptors. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21887137 History of cannabis use is not associated with alterations in striatal dopamine D2/D3 receptor availability. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21890594 Popular intoxicants: what lessons can be learned from the last 40 years of alcohol and cannabis regulation? (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21926420 Deletion of CB2 cannabinoid receptor induces schizophrenia-related behaviors in mice. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21430651 The schizophrenia susceptibility gene neuregulin 1 modulates tolerance to the effects of cannabinoids. (abst 2011)
584
Association between a cannabinoid receptor gene (CNR1) polymorphism and cannabinoid-induced alterations of the auditory event-related P300 potential. (abst 2011)
Marijuana Use Associated With 'Superior' Cognitive Performance In Schizophrenic Patients, Study Says (news 2011) http://www.norml.org/index.cfm?Group_ID=8537 Omega-3 PUFA Deficiency Abolishes Endocannabinoid-Linked Neuronal Functions (news - 2011) http://www.fatsoflife.com/article.php?nid=1&edition=this&id=1837&issueid=85 A Brain Wrought Without Omega-3 (news 2011) (news 2011)
Debunking the Myth of a Link Between Marijuana and Mental Illness

http://www.alternet.org/drugs/151776
The Link Between Marijuana and Schizophrenia
(news 2011)
http://www.time.com/time/health/article/0,8599,2005559,00.html
SCLERODERMA The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities (full - 2009)
The cannabinoid receptor CB2 exerts antifibrotic effects in experimental dermal fibrosis (full - 2009) http://www3.interscience.wiley.com/cgi-bin/fulltext/122290593/HTMLSTART Cannabinoids inhibit fibrogenesis in diffuse systemic sclerosis fibroblasts
http://rheumatology.oxfordjournals.org/content/48/9/1050.full
(full - 2009)
The cannabinoid WIN55, 212-2 abrogates dermal fibrosis in scleroderma bleomycin model. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/21177293
585
Targeting the cannabinoid pathway limits the development of fibrosis and autoimmunity in a mouse model of systemic sclerosis. (abst 2010)
SEPTIC SHOCK Protection Against Septic Shock and Suppression of Tumor Necrosis Factor and Nitric Oxide Production by Dexanabinol (HU-211), a Nonpsychotropic Cannabinoid (full - 1997) http://jpet.aspetjournals.org/content/283/2/918.full Presynaptic cannabinoid CB1 receptors are involved in the inhibition of the neurogenic vasopressor response during septic shock in pithed rats (full - 2004)
Effects of AM281, a cannabinoid antagonist, on systemic haemodynamics, internal carotid artery blood flow and mortality in septic shock in rats (full 2005)
Effects of AM281, a cannabinoid antagonist, on circulatory deterioration and cytokine production in an endotoxin shock model: comparison with norepinephrine. (abst 2006)
The cannabinoid receptor 2 is critical for the host response to sepsis. (full 2009)
Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression. (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005548/?tool=pubmed Treatment with cannabidiol reverses oxidative stress parameters, cognitive impairment and mortality in rats submitted to sepsis by cecal ligation and puncture. (abst - 2010)
The endocannabinoid system in sepsis a potential target to improve microcirculation? (full 2011)
http://www.signavitae.com/articles/review-articles/161-the-endocannabinoid-system-in-sepsis-a-potentialtarget-to-improve-microcirculation
586
SICKLE CELL DISEASE Cannabis use in sickle cell disease: a questionnaire study. (abst - 2005)
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=16173972&dopt=Abstrac t
Medical use of cannabis in sickle cell disease
(news - 2005)
http://www.chanvre-info.ch/info/it/Medical-use-of-cannabis-in-sickle.html
The prevalence of marijuana smoking in young adults with sickle cell disease: a longitudinal study (full - 2006)
http://caribbean.scielo.org/scielo.php?script=sci_arttext&pid=S004331442006000400004&lng=en&nrm=iso
Marijuana Use Prevalent Among Sickle Cell Patients

news - 2007)
Marijuana Use and Sickle Cell Disease
(abst - 2008)
Cannabinoids as Analgesics for Pain in Sickle Cell Disease.
(abst - 2009)
New Era Dawns on Sickle Cell Pain
(full - 2010)
http://bloodjournal.hematologylibrary.org/cgi/reprint/116/3/311
Pain related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: modulation by cannabinoids. (full - 2010)
http://bloodjournal.hematologylibrary.org/content/116/3/456.long
Cannibinoids Offer Novel Treatment for Pain in Sickle Cell Disease, Study Suggests (news - 2010) http://www.sciencedaily.com/releases/2010/07/100722121225.htm Mouse models for studying pain in sickle disease: effects of strain, age, and acuteness. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22171826
SINUSITIS HEMP AS A MEDICAMENT : Cannabis indica in oto-rhino-laryngology (full - 1955)

https://www.greenpassion.org/index.php?/topic/23450-cannabis-indica-in-oto-rhino-laryngology/
587
SLEEPING SICKNESS/ TRYPANOSOMIASIS The trypanocidal effect of Cannabis sativa constituents in experimental animal trypanosomiasis. (African Sleeping Sickness) (abst 1994)
SLEEP MODULATION Effect of cannabis and certain of its constituents on pentobarbitone sleeping time and phenazone metabolism (full - 1972) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1666020/ Therapeutic aspects of cannabis and cannabinoids.
(full - 2001) (full - 2002)
Functional role for cannabinoids in respiratory stability during sleep.

http://science.iowamedicalmarijuana.org/pdfs/lungs/Carley%202002.pdf
The cannabinoids R(-)-7-hydroxy-delta-6-tetra-hydrocannabinol-dimethylheptyl (HU210), 2-O-arachidonoylglycerylether (HU-310) and arachidonyl-2-chloroethylamide (ACEA) increase isoflurane provoked sleep duration by activation of cannabinoids 1 (CB1)-receptors in mice. (abst 2002) http://www.ncbi.nlm.nih.gov/pubmed/12095655 THC reduces sleep apnoea in animal research (news - 2002)
Anandamide enhances extracellular levels of adenosine and induces sleep: an in vivo microdialysis study. (abst - 2003)
Effect of Delta-9-tetrahydrocannabinol and cannabidiol on nocturnal sleep and earlymorning behavior in young adults. (abst - 2004)
Efficacy of two cannabis based medicinal extracts for relief of central neuropathic pain from brachial plexus avulsion: results of a randomised controlled trial. (abst - 2004)
Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis. (abst - 2005)
588
Cannabinoids attenuate norepinephrine-induced melatonin biosynthesis in the rat pineal gland by reducing arylalkylamine N-acetyltransferase activity without involvement of cannabinoid receptors. (full 2006)
Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats.

(abst - 2006)
Cannabis, pain, and sleep: lessons from therapeutic clinical trials of Sativex, a cannabisbased medicine. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17712817 Dronabinol and marijuana in HIV-positive marijuana smokers. Caloric intake, mood, and sleep. (abst - 2007) http://marijuana.researchtoday.net/archive/4/8/1234.htm Cannabinoids Associated With "More Restful Sleep," Study Says
(news - 2007)
Effect of illicit recreational drugs upon sleep: Cocaine, ecstasy and marijuana. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18313952?dopt=AbstractPlus The nonpsychoactive cannabis constituent cannabidiol is a wake-inducing agent. (abst - 2008)
http://www.unboundmedicine.com/medline/ebm/record/19045957/abstract/The_nonpsychoactive_cannabis _constituent_cannabidiol_is_a_wake_inducing_agent_
The Effects of Nabilone on Sleep in Fibromyalgia: Results of a Randomized Controlled Trial. (full - 2009) http://www.anesthesia-analgesia.org/content/110/2/604.long Smoked cannabis for chronic neuropathic pain: a randomized controlled trial (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950205/?tool=pmcentrez Endocannabinoid signalling: has it got rhythm? (full 2010)
The Maternal Lifestyle Study: Sleep Problems in Children with Prenatal Substance Exposure (full 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917192/?tool=pubmed Sleep and Medicinal Cannabis (abst - 2010)
http://www.cmcr.ucsd.edu/index.php?option=com_content&view=article&id=151:sleep-and-medicinalcannabis&catid=41:research-studies&Itemid=135
Study: Smoking pot may ease chronic pain
(news - 2010)
589
Effects on sleep and dopamine levels of microdialysis perfusion of cannabidiol into the lateral hypothalamus of rats. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21262236 A study on the endogenous cannabinoid system synthetic and catabolic enzyme levels in patients with obstructive sleep apnea. (abst 2011)
Medical marijuana turns former soldier's life around
(news 2011)
Treat aleep apnea with medical marijuana (news 2011)

http://www.examiner.com/holistic-health-in-boulder/treat-sleep-apnea-with-medical-marajuana
SMALLPOX (also see COW POX) Cannabinoids lead to enhanced virulence of the smallpox vaccine (vaccinia) virus. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21131094/abstract/Cannabinoids_lead_to_enhance d_virulence_of_the_smallpox_vaccine__vaccinia__virus_
SMELL / ODOR DETECTION Marijuana Odor Perception (full 2004)

http://www.cannabis-science.com/papers/Cannabis%20Smell%20Searches%20Paperfull.pdf
(full 2007)
The endocannabinoid 2-arachidonoyl-glycerol controls odor sensitivity in larvae of Xenopus laevis. (full 2010) http://www.jneurosci.org/content/30/26/8965.long
590
Endocannabinoid modulation in the olfactory epithelium. (abst 2010)

Delta-9-tetrahydrocannabinol may palliate altered chemosensory perception in cancer patients: results of a randomized, double-blind, placebo-controlled pilot trial (full 2011) http://annonc.oxfordjournals.org/content/early/2011/02/11/annonc.mdq727.full Acute Immobilization Stress Modulate GABA Release from Rat Olfactory Bulb: Involvement of EndocannabinoidsCannabinoids and Acute Stress Modulate GABA Release (full 2011) http://www.hindawi.com/journals/ijcb/2011/529851/ Cannabinoid receptor-mediated regulation of neuronal activity in the main olfactory bulb (abst 2011)
SMOKED CANNABIS AS A MEDICATION CANNABIS AND MARINOL IN THE TREATMENT OF MIGRAINE HEADACHE (full - no date) http://www.druglibrary.org/schaffer/hemp/migrn2.htm Marihuana smoking and intraocular pressure. (abst - 1971)
Smoked marijuana and oral delta-9-THC on specific airway conductance in asthmatic subjects (full - 1974) http://www.ukcia.org/research/SmokedAndOralInAsthmatic.php Effects of smoked marijuana in experimentally induced asthma.
http://www.ukcia.org/research/InducedAsthma/index.php
(full - 1975)
Anticonvulsant nature of marihuana smoking
(abst - 1975)
Short-term effects of smoked marihuana on left ventricular function in man (full - 1977)
http://chestjournal.chestpubs.org/content/72/1/20.full.pdf+html?maxtoshow=&hits=80&RESULTFORMA T=&fulltext=cannabis&searchid=1&FIRSTINDEX=640&resourcetype=HWCIT
Effect of marihuana on intraocular and blood pressure in glaucoma
(full - 1980)
Comparison of effects of marihuana cigarettes of three different potencies (full - 1982)

http://www.nature.com/clpt/journal/v31/n5/pdf/clpt198286a.pdf
591
Oral vs. Inhaled Cannabinoids for Nausea/Vomiting from Cancer Chemotherapy (full - 1988) http://www.medmjscience.org/Pages/science/pierson.html Effects of smoked marijuana on food intake and body weight of humans living in a residential laboratory. (abst - 1988) http://www.cannabismed.org/studies/ww_en_db_study_show.php?s_id=117
Marijuana Smoking: Factors That Influence the Bioavailability of Tetrahydrocannabinol (full - 1990) http://www.ukcia.org/research/FactorsThatInfluenceBioavailability.pdf Effects of delta 9-THC on marijuana smoking, dose choice, and verbal report of drug liking. (full - 1994) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1334408/?tool=pubmed The perceived effects of smoked cannabis on patients with multiple sclerosis. (abst - 1997) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=13 Marijuana Smoking vs Cannabinoids for Glaucoma Therapy
http://archopht.ama-assn.org/cgi/content/full/116/11/1433
(full - 1998)
Antiemetic efficacy of smoked marijuana: subjective and behavioral effects on nausea induced by syrup of ipecac. (abst - 2001)
Chronic Cannabis Use in the Compassionate Investigational New Drug Program (full - 2002) http://www.maps.org/mmj/russo2002.pdf The Role of Cannabis and Cannabinoids in Pain Management
(full 2002)
A Dramatic Response to Inhaled Cannabis in a Woman with Central Thalamic Pain and Dystonia (full - 2002) http://www.jpsmjournal.com/article/PIIS0885392402004268/fulltext Chronic Cannabis Use in the Compassionate Investigational New Drug Program (abstract & comments- 2002) http://www.letfreedomgrow.com/cmu/chronic_cannabis_use.htm The effects of smoked cannabis in painful peripheral neuropathy and cancer pain refractory to opiods. (abst - 2003)
Study: Brain Not Permanently Damaged by Marijuana Marijuana Smoking Doesn't Kill Epilepsy patients are smoking pot (news - 2003) (news - 2004)
(news - 2003)
http://www.drugfree.org/join-together/drugs/study-brain-not-permanently
592
Marinol vs Natural Cannabis
(full - 2005)
http://www.norml.org/pdf_files/NORML_Marinol_vs_Natural_Cannabis.pdf
Smoked cannabis therapy for HIV-related painful peripheral neuropathy: results of a randomized, placebo-controlled clinical trial. (abst - 2005)
Medical use of cannabis in sickle cell disease
(news - 2005)
http://www.chanvre-info.ch/info/it/Medical-use-of-cannabis-in-sickle.html
Evaluation of herbal cannabis characteristics by medical users: a randomized trial (full - 2006)
Marijuana smoking in young adults with sickle cell

http://www.illinoisnorml.org/content/view/309/
(news - 2006)
Single and multiple doses of rimonabant antagonize acute effects of smoked cannabis in male cannabis users. (full - 2007)
Dose-dependent Effects of Smoked Cannabis on Capsaicin-Induced Pain and Hyperalgesia in Healthy Volunteers. (full - 2007)
http://www.cmcr.ucsd.edu/geninfo/Wallace_2007.pdf
(abst - 2007)
Study Supports Medical Marijuana Use
(news - 2007) (news - 2007)
http://www.drugfree.org/join-together/drugs/study-supports-medical
Smoked Cannabis Proven Effective In Treating Neuropathic Pain

Marijuana gives relief from chronic pain for AIDS sufferers

(news - 2007)
Smoked Cannabis Reduces Foot Pain Associated With HIV In Placebo Trial (news - 2007) http://www.sciencedaily.com/releases/2007/02/070212185335.htm
593
A Randomized, Placebo Controlled Cross-Over Trial of Cannabis Cigarettes in Neuropathic Pain (full - 2008) http://www.cmcr.ucsd.edu/geninfo/Wilsey_2008.pdf Medicinal Marijuana Effective For Neuropathic Pain In HIV, Study Finds (news - 2008) http://www.sciencedaily.com/releases/2008/08/080806113135.htm Marijuana May Be Effective For Neuropathic Pain (news - 2008) (abst - 2009)

3.0 Dosing
(abst - 2009)
http://www.hc-sc.gc.ca/dhp-mps/marihuana/how-comment/medpract/infoprof/dosing-posologie-eng.php
Smoked cannabis for chronic neuropathic pain: a randomized controlled trial (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950205/?tool=pmcentrez Cannabinoid receptor 1 binding activity and quantitative analysis of Cannabis sativa L. smoke and vapor. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20118579 The relationship between substance use and posttraumatic stress disorder in a methadone maintenance treatment program. (abst 2010)
Medicinal Marijuana Strains
(news 2010) (news 2010)
http://www.thefreelibrary.com/Medicinal+Marijuana+Strains-a01074139322
Smoking cannabis relieves chronic pain
http://www.independent.co.uk/life-style/health-and-families/smoking-cannabis-relieves-chronic-pain2067287.html
Cannabis Inhalation Associated With Spontaneous Tumor Regression
(news - 2010)
http://blog.norml.org/2011/03/22/cannabis-inhalation-associated-with-spontaneous-tumor-regression-studysays/
Study: Smoking pot may ease chronic pain
(news - 2010)
594
Marijuana better than pharmaceuticals at treating chronic pain, improving mood (news - 2010) http://www.naturalnews.com/029662_marijuana_chronic_pain.html Chronic Pain Improved by Cannabis Smoking (news 2010)
http://news.softpedia.com/news/Chronic-Pain-Improved-by-Cannabis-Smoking-154254.shtml
Spontaneous regression of septum pellucidum/forniceal pilocytic astrocytomas-possible role of Cannabis inhalation. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21336992 Medical cannabis use in post-traumatic stress disorder: a naturalistic observational study. (abst 2011) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=481 Inhaled Cannabis May Keep Brain Cancer in Remission (news 2011)
http://www.freedomisgreen.com/inhaled-marijuana-may-keep-brain-cancer-in-remission/
SOCIAL ADJUSTMENT/ BEHAVIOR MARIHUANA INTOXICATION (abst -1934)

http://ajp.psychiatryonline.org/cgi/content/abstract/91/2/303?maxtoshow=&hits=80&RESULTFORMAT= &fulltext=marihuana&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT
MARIHUANA AND AGGRESSIVE CRIME
(abst - 1946)
Marihuana Use and Psychosocial Adaptation
(abst - 1974)
Ganja in Jamaica (book 1976) http://www.cifas.us/cannabis/PDFs/OCRGanjainJamaica.pdf The Effect of Marijuana on Small Group Process. (abst 1977)
http://medical-journals.healia.com/doc/612199/The-effect-of-marijuana-on-small-group-process
Delta9-tetrahydrocannabinol: antiaggressive effects in mice, rats, and squirrel monkeys (abst - 1978)
http://www.sciencemag.org/cgi/content/abstract/199/4336/1459?maxtoshow=&hits=80&RESULTFORMA T=&fulltext=marihuana&searchid=1&FIRSTINDEX=240&resourcetype=HWCIT
Adolescent Marihuana Use: Role of Parents and Peers. Marihuana and mood in human volunteers.
(abst 1976)
http://medical-journals.healia.com/doc/4726001/Adolescent-marihuana-use-role-of-parents-and-peers
(abst 1978)
595
Long-term cannabis use: characteristics of users in an Australian rural area. (abst - 1998) http://www.ncbi.nlm.nih.gov/pubmed/9744119 Effects of THC on Behavioral Measures of Impulsivity in Humans
(full - 2003)
Cannabis Use Not Linked with Psychosocial Harm

(news - 2004)
Cannabis, motivation, and life satisfaction in an internet sample (full - 2006)

Negative consequences associated with dependence in daily cannabis users (full - 2007) http://www.substanceabusepolicy.com/content/2/1/3 Some go without a cigarette: characteristics of cannabis users who have never smoked tobacco. (full - 2007) http://archpedi.ama-assn.org/cgi/content/full/161/11/1042 Marijuana use motives and social anxiety among marijuana-using young adults. (abst - 2007) http://marijuana.researchtoday.net/archive/4/8/1303.htm Teens who use only cannabis appear to function better than those who also use tobacco (news - 2007) http://www.news-medical.net/news/2007/11/06/32262.aspx Are Cigarettes More of a Drag on Teens than Marijuana? (news - 2007)
Teens Who Smoke Marijuana But Not Tobacco Are Different From Other Teen Groups (news - 2007) http://www.sciencedaily.com/releases/2007/11/071105164453.htm Cannabinoid Modulation of Amygdala Reactivity to Social Signals of Threat in Humans (full - 2008)
Characteristics of Adolescents Who Use Cannabis But Not Tobacco

(news - 2008)
Cannabidiol reverses the reduction in social interaction produced by low dose Delta(9)tetrahydrocannabinol in rats. (abst 2009) http://www.ncbi.nlm.nih.gov/pubmed/19393686
596
Sex difference in cell proliferation in developing rat amygdala mediated by endocannabinoids has implications for social behavior. (full 2010)
Cannabis and crime: findings from a longitudinal study.
(abst - 2010)
http://www.unboundmedicine.com/medline/ebm/record/19839964/full_citation/Cannabis_and_crime:_findi ngs_from_a_longitudinal_study_
Drug-Intake Methods and Social Identity: The Use of Marijuana in Blunts Among Southeast Asian Adolescents and Emerging Adults. (full 2011)
The social contagion effect of marijuana use among adolescents.

(full 2011)
Racial differences in trajectories of heavy drinking and regular marijuana use from ages 13 to 24 among African-American and White males. (abst 2011)
Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-nave social phobia patients. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21307846 Profile of Psychoactive Substances Consumption in Workplace.
(abst 2011)
Alcohol and cannabis abuse/dependence symptoms and life satisfaction in young adulthood. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21733007 Popular intoxicants: what lessons can be learned from the last 40 years of alcohol and cannabis regulation? (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21926420 The association between early conduct problems and early marijuana use in college students. (abst 2011) http://marijuana.researchtoday.net/archive/8/9/4850.htm The Kids Are All Right, Even if Their Parents Grow Pot (news 2011)
http://www.parentdish.com/2011/07/27/the-kids-are-all-right-even-if-their-parents-grow-pot/
SPASTICITY How Cannabis Compares to other treatments (no date - 2008)

597
The perceived effects of marijuana on spinal cord injured males.

(abst - 1974) (abst - 1980) (abst - 1981)

Treatment of human spasticity with delta 9-tetrahydrocannabinol.

Cannabis effect on spasticity in spinal cord injury.
(abst - 1982) (abst - 1986)
Effect of Delta-9-THC on EMG Measurements in Human Spasticity

The effect of delta-9-THC on human spasticity.
(abst - 1986)
Delta-9-THC in the treatment of spasticity associated with multiple sclerosis. (abst - 1987)
Effect of cannabinoids on spasticity and ataxia in multiple sclerosis.

(abst - 1989)
Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects in a single case double-blind trial. (abst + 1st page - 1990)
http://www.springerlink.com/content/3826667673770p51/fulltext.pdf?page=1
Nabilone in the treatment of multiple sclerosis.
(abst - 1995)
(full - 2000)
Cannabinoids in the treatment of pain and spasticity in multiple sclerosis.
(abst - 2002)
598

(abst - 2003)
The treatment of spasticity with D9-tetrahydrocannabinol (D9-THC) in patients with spinal cord injury (abst - 2003)
Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patients. (abst - 2004)
Efficacy of tetrahydrocannabinol in patients refractory to standard antiemetic therapy.Efficacy, safety and tolerability of an orally administered cannabis extract in the treatment of spasticity in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled, crossover study. (abst - 2004)

(abst - 2004) (full - 2005)
CB1 cannabinoid receptor-mediated modulation of food intake in mice

Cannabinoids in multiple sclerosis (CAMS) study: safety and efficacy data for 12 months follow up. (abst - 2005)
Cannabis-based medicinal extract (Sativex) produced significant improvements in a subjective measure of spasticity which were maintained on long-term treatment with no evidence of tolerance. (abst - 2005)
The treatment of spasticity with Delta(9)-tetrahydrocannabinol in persons with spinal cord injury. (abst - 2006)
http://www.unboundmedicine.com/medline/ebm/record/16988792/abstract/Low_dose_treatment_with_the_ synthetic_cannabinoid_Nabilone_significantly_reduces_spasticity_related_pain_:_A_double_blind_placeb o_controlled_cross_over_trial_
Long-term use of a cannabis-based medicine in the treatment of spasticity and other symptoms in multiple sclerosis. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/17086911
599
Randomized controlled trial of cannabis-based medicine in spasticity caused by multiple sclerosis (full - 2007)
http://medicalcannabis.com/images/pdf09/indications/ms/collin_et_al_2007_sativex.pdf
Motor effects of delta 9 THC in cerebellar Lurcher mutant mice.
(abst - 2007)
http://www.unboundmedicine.com/medline/ebm/record/17531329/abstract/Motor_effects_of_delta_9_THC _in_cerebellar_Lurcher_mutant_mice
Cannabinoids in the management of spasticity associated with multiple sclerosis (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626929/?tool=pmcentrez Whole plant cannabis extracts in the treatment of spasticity in multiple sclerosis: a systematic review (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793241/ Marijuana Eases Spasticity in MS Patients (news 2009)
http://www.webmd.com/multiple-sclerosis/news/20091204/marijuana-eases-spasticity-in-ms-patients

(news - 2009)
Cannabis can reduce spasticity in MS patients
(news - 2009)
http://www.news-medical.net/news/20091204/Cannabis-can-reduce-spasticity-in-MS-patients.aspx
New approaches in the management of spasticity in multiple sclerosis patients: role of cannabinoids (full - 2010)
THC and CBD oromucosal spray (Sativex) in the management of spasticity associated with multiple sclerosis. (abst -2011)
(abst 2011)
600
SPICE various synthetic cannabinoid mixtures - also see the HU and JWH and CP series Withdrawal Phenomena and Dependence Syndrome After the Consumption of "Spice Gold" (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719097/?tool=pmcentrez Spice: a never ending story? (abst 2009) http://www.ncbi.nlm.nih.gov/pubmed/19589652

Chemical analysis of synthetic cannabinoids as designer drugs in herbal products. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20117892 Spice drugs as a new trend: mode of action, identification and legislation.
(abst 2010)
Monitoring of herbal mixtures potentially containing synthetic cannabinoids as psychoactive compounds. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20857386 Inhaled Incense "K2" May Cause Heart Damage (news 2010)
http://drwes.blogspot.com/2010/08/inhaled-incense-k2-may-cause-heart.html
Marijuana-based Drugs: Innovative Therapeutics or Designer Drugs of Abuse? (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139381/?tool=pubmed Beyond THC: The New Generation of Cannabinoid Designer Drugs.
(full 2011)
Investigating a not-so-natural high.

http://pubs.acs.org/doi/full/10.1021/ac900564u
(full 2011) (full 2011)
Convulsions Associated with the Use of a Synthetic Cannabinoid Product.

http://www.springerlink.com/content/9651q2672027n38g/fulltext.html
Liquid chromatography-tandem mass spectrometry analysis of urine specimens for K2 (JWH-018) metabolites. (full 2011)
Psychosis Associated With Synthetic Cannabinoid Agonists: A Case Series (letter 2011) http://ajp.psychiatryonline.org/cgi/content/full/168/10/1119 The "new" marijuana. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21325097
601
The impact of changes in UK classification of the synthetic cannabinoid receptor agonists in 'Spice'. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21482092 Severe toxicity following synthetic cannabinoid ingestion.
(abst 2011)

(abst 2011)

(abst 2011)
(abst 2011) (abst 2011) (abst 2011) (abst 2011)
"Legal highs" - new players in the old drama.


Synthetic cannabinoid use: a case series of adolescents.

Myocardial Infarction Associated With Use of the Synthetic Cannabinoid K2. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22065271 Cytotoxicity of synthetic cannabinoids found in "Spice" products: the role of cannabinoid receptors and the caspase cascade in the NG 108-15 cell line. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21907772/abstract/Cytotoxicity_of_synthetic_cann abinoids_found_in_%22Spice%22_products:_the_role_of_cannabinoid_receptors_and_the_caspase_cascad e_in_the_NG_108_15_cell_line_
High-performance sport, marijuana, and cannabimimetics.

(abst 2011)

Marijuana-based drugs: innovative therapeutics or designer drugs of abuse? (abst 2011)

http://www.unboundmedicine.com/medline/ebm/record/21441120/abstract/Marijuana_based_drugs:_innov ative_therapeutics_or_designer_drugs_of_abuse
602
Detection of synthetic cannabinoids in herbal incense products.

(abst 2011)
(news 2011)
Chemicals Used in "Spice" and "K2" Type Products Now Under Federal Control and Regulation (news 2011) http://www.justice.gov/dea/pubs/pressrel/pr030111.html A survey study to characterize use of Spice products (synthetic cannabinoids). (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/21835562 'Hammer Head' 'incense' blamed for seizure of youth in Le Roy (news 2012)
http://thebatavian.com/howard-owens/hammer-head-incense-blamed-seizure-youth-le-roy/29983
SPINAL CORD INJURY The perceived effects of marijuana on spinal cord injured males. (abst - 1974)
Marihuana as a therapeutic agent for muscle spasm or spasticity. (abst - 1980)

Cannabis effect on spasticity in spinal cord injury. The effect of delta-9-THC on human spasticity.
(abst - 1982)
(abst - 1986)
Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects in a single case double-blind trial. (abst - 1990)
Involvement of Dynorphin B in the Antinociceptive Effects of the Cannabinoid CP55,940 in the Spinal Cord (full - 1997) http://jpet.aspetjournals.org/content/281/2/730.full Cannabis and cannabinoids: pharmacology and rationale for clinical use
(abst 1999)
603
Selective cannabinoid CB1 receptor activation inhibits spinal nociceptive transmission in vivo. (full 2001) http://jn.physiology.org/content/86/6/3061.long Clinical investigation of delta-9-tetrahydrocannabinol (THC) as an alternative therapy for overactive bladders in spinal cord injury (SCI) patients. (abst - 2001)
The treatment of spasticity with D9-tetrahydrocannabinol (D9-THC) in patients with spinal cord injury (abst - 2003)

(abst - 2003) (abst - 2004)

Treatments for Chronic Pain in Persons With Spinal Cord Injury: A Survey Study (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1864800/?tool=pmcentrez Antinociceptive effect of cannabinoid agonist WIN 55,2122 in rats with a spinal cord injury (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1861843/?tool=pmcentrez Effects of a Cannabinoid Agonist on Spinal Nociceptive Neurons in a Rodent Model of Neuropathic Pain (full - 2006) http://jn.physiology.org/cgi/content/full/96/6/2984 The treatment of spasticity with Delta(9)-tetrahydrocannabinol in persons with spinal cord injury. (abst - 2006)
Effects of palmitoylethanolamide on signaling pathways implicated in the development of spinal cord injury. (full 2008) http://jpet.aspetjournals.org/content/326/1/12.long Sustained antinociceptive effect of cannabinoid receptor agonist WIN 55,212-2 over time in rat model of neuropathic spinal cord injury pain (full - 2009)
Cannabinoid receptor-mediated antinociception with acetaminophen drug combinations in rats with neuropathic spinal cord injury pain. (full 2010)
Effect of dronabinol on central neuropathic pain after spinal cord injury: a pilot study. (abst 2010) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=313
604
The endocannabinoid 2-arachidonoylglycerol reduces lesion expansion and white matter damage after spinal cord injury. (abst - 2010)
A randomized, double-blinded, crossover pilot study assessing the effect of nabilone on spasticity in persons with spinal cord injury. (abst - 2010)
Effects of palmitoylethanolamide on release of mast cell peptidases and neurotrophic factors after spinal cord injury. (abst 2011)
Targetting CB1 Cannabinoid Receptor for Neuroprotetion in Spinal Cord Injury (abst 2011)
http://www.fasebj.org/cgi/content/meeting_abstract/25/1_MeetingAbstracts/lb422?maxtoshow=&hits=80& RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype =HWCIT
Spinal Cord Injuries Induce Changes of CB1 Cannabinoid Receptor and C-C Chemokine Expression in Brain Areas Underlying Circuitry of Chronic Pain Conditions. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21265596/abstract/Spinal_Cord_Injuries_Induce_ Changes_of_CB1_Cannabinoid_Receptor_and_C_C_Chemokine_Expression_in_Brain_Areas_Underlying _Circuitry_of_Chronic_Pain_Conditions_
Modulation of inflammatory responses by a cannabinoid-2-selective agonist after spinal cord injury. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21970496 Activation of spinal and supraspinal cannabinoid-1 receptors leads to antinociception in a rat model of neuropathic spinal cord injury pain. (abst 2011)
Cannabidiol-treated Rats Exhibited Higher Motor Score After Cryogenic Spinal Cord Injury. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21915768 Spinal cannabinoid CB2 receptors as a target for neuropathic pain: an investigation using chronic constriction injury. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22210507
605
SPLEEN Molecular characterization of a peripheral receptor for cannabinoids

(abst 1993)
A Cyclooxygenase Metabolite of Anandamide Causes Inhibition of Interleukin-2 Secretion in Murine Splenocytes (full 2004)
Regulatory effect of cannabinoid receptor agonist on chemokine-induced lymphocyte chemotaxis. (full 2011) http://www.jstage.jst.go.jp/article/bpb/34/7/1090/_pdf Cannabinoid receptor 2 positions and retains marginal zone B cells within the splenic marginal zone. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21875957
STEM CELLS Expression and function of cannabinoid receptors CB1 and CB2 and their cognate cannabinoid ligands in murine embryonic stem cells. (full 2007)
CB2 cannabinoid receptors promote mouse neural stem cell proliferation. (abst 2007)
Endocannabinoids are expressed in bone marrow stromal niches and play a role in interactions of hematopoietic stem and progenitor cells with the bone marrow microenvironment (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20826813 Cannabinoid receptor 2 and its agonists mediate hematopoiesis and hematopoietic stem and progenitor cell mobilization. (abst 2011)
Pleiotropic effects of prostaglandin E(2) in hematopoiesis; prostaglandin E(2) and other eicosanoids regulate hematopoietic stem and progenitor cell function. (abst 2011)
Scientists Meet to Discuss Cannabinoids and Stem Cells
(news 2011)
http://www.examiner.com/medical-marijuana-in-philadelphia/scientists-meet-to-discuss-cannabinoids-andstem-cells#ixzz1RmgEd9oq
606
STRESS - also see ANXIETY, POST TRAUMATIC STRESS DISORDER Cannabinoid CB1-mediated inhibition of stress-induced gastric ulcers in rats (abst 2000) http://www.springerlink.com/content/w3jc8rk16k9p92fl/ Synergistic Interactions between Cannabinoids and Environmental Stress in the Activation of the Central Amygdala (full - 2005)
Body's Own Marijuana-Like Compounds Are Crucial For Stress-Induced Pain Relief (news - 2005) http://www.sciencedaily.com/releases/2005/06/050628064435.htm Endocannabinoids -- The Brain's Cannabis -- Demonstrate Novel Modes Of Action To Stress (news - 2005) http://www.sciencedaily.com/releases/2005/07/050720065810.htm Endocannabinoids Mediate the Effects of Acute Stress and Corticosterone on Sex Behavior (full 2007) http://endo.endojournals.org/content/148/2/493.full Association of the Cannabinoid Receptor Gene (CNR1) With ADHD and Post-Traumatic Stress Disorder (full - 2008)
(full - 2009)
Effects of {Delta}9-tetrahydrocannabinol on reward and anxiety in rats exposed to chronic unpredictable stress. (abst - 2009)

(full - 2010)

(full - 2010)
Deficiency in Endocannabinoid Signaling in the Nucleus Accumbens Induced by Chronic Unpredictable Stress (abst - 2010)
607
Endocannabinoids and the cardiovascular response to stress.

(abst - 2011)
Cannabinoid receptor expression and phosphorylation are differentially regulated between male and female cerebellum and brain stem after repeated stress: Implication for PTSD and drug abuse. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21600961 Endocannabinoid signaling in the amygdala: anatomy, synaptic signaling, behavior, and adaptations to stress. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21884761 Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress. (abst 2011)
Cannabinoids Prevent the Development of Behavioral and Endocrine Alterations in a Rat Model of Intense Stress. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21918506
STORAGE The stability of cannabis and its preparations on storage.

(abst 1976) (abst 1977)
The decomposition of acidic and neutral cannabinoids in organic solvents.

Constituents of Cannabis sativa L. XIII: Stability of dosage form prepared by impregnating synthetic (--)-delta 9-trans-tetrahydrocannabinol on placebo Cannabis plant material. (abst 1978) http://www.ncbi.nlm.nih.gov/pubmed/660481 Stability of Cannabis sativa L. samples and their extracts, on prolonged storage in Delhi. (full 1978) http://www.lycaeum.org/leda/docs/16647.shtml?ID=16647 Stability of Cannabinoids in Dried Samples of Cannabis Dating from Around 1896-1905. (abst 1990) http://medical-journals.healia.com/doc/2314109/Stability-of-cannabinoids-in-driedsamples-of-cannabis-dating-from-around-1896-1905
STROKE The inhibitory effects of cannabinoids, the active constituents of Cannabis sativa L. on human and rabbit platelet aggregation. (abst - 1989)
608
HU-211, a Novel Noncompetitive N-Methyl-D-Aspartate Antagonist, Improves Neurological Deficit and Reduces Infarct Volume After Reversible Focal Cerebral Ischemia in the Rat (full - 1995) http://stroke.ahajournals.org/cgi/content/full/26/12/2313 Marijuana chemical tapped to fight strokes ? Dope hope for stroke victims (news - 1998) (news - 1998)
http://findarticles.com/p/articles/mi_m1200/is_n2_v154/ai_20973037/?tag=content;col1
Cannabinoids and Neuroprotection in Global and Focal Cerebral Ischemia and in Neuronal Cultures (full - 1999)
Dexanabinol; a novel neuroprotective drug in experimental focal cerebral ischemia. (abst 1999) http://www.ncbi.nlm.nih.gov/pubmed/10202976 Increased Severity of Stroke in CB1 Cannabinoid Receptor Knock-Out Mice (full - 2002)
Drug-induced hypothermia reduces ischemic damage: effects of the cannabinoid HU-210. (full - 2003) http://stroke.ahajournals.org/cgi/reprint/34/8/2000 US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants
(full - 2003)

(abst - 2003)
Cannabidiol prevents infarction via the non-CB1 cannabinoid receptor mechanism. (abst 2004) http://www.ncbi.nlm.nih.gov/pubmed/15640760 Cannabidiol Prevents Cerebral Infarction Via a Serotonergic 5-Hydroxytryptamine1A ReceptorDependent Mechanism (full - 2005)
http://stroke.ahajournals.org/cgi/content/full/36/5/1071
(news - 2005)
609
Characterization of the neuroprotective effect of the cannabinoid agonist WIN-55212 in an in vitro model of hypoxic-ischemic brain damage in newborn rats. (abst 2006)
The CB1 Cannabinoid Receptor Mediates Excitotoxicity-induced Neural Progenitor Proliferation and Neurogenesis (full - 2007) http://www.jbc.org/content/282/33/23892.full Cannabinoid CB2 receptor activation decreases cerebral infarction in a mouse focal ischemia/reperfusion model (full - 2007)
Delayed treatment with cannabidiol has a cerebroprotective action via a cannabinoid receptor-independent myeloperoxidase-inhibiting mechanism. (full - 2007)
Delta(9)-tetrahydrocannabinol (Delta(9)-THC) prevents cerebral infarction via hypothalamic-independent hypothermia. (abst - 2007)

(abst - 2007)

(full - 2008)
Modulation of the balance between cannabinoid CB(1) and CB(2) receptor activation during cerebral ischemic/reperfusion injury (full - 2008)
http://science.iowamedicalmarijuana.org/pdfs/neuro/Zhang%202008.pdf
Cannabinoid receptors in acute and chronic complications of atherosclerosis (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219535/?tool=pmcentrez Endocannabinoids and cannabinoid receptors in ischaemiareperfusion injury and preconditioning (full - 2008)
Cannabidiol prevents a post-ischemic injury progressively induced by cerebral ischemia via a high-mobility group box1-inhibiting mechanism. (abst - 2008)
Endocannabinoids mediate neuroprotection after transient focal cerebral ischemia. (abst 2008) http://www.ncbi.nlm.nih.gov/pubmed/18823959.
610
Modulation of cannabinoid receptor activation as a neuroprotective strategy for EAE and stroke. (full 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855650/?tool=pubmed Therapeutic time window of cannabidiol treatment on delayed ischemic damage via highmobility group box1-inhibiting mechanism. (full 2009)
Post-ischemic brain damage: the endocannabinoid system in the mechanisms of neuronal death. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19087195 CB2 receptor activation attenuates microcirculatory dysfunction during cerebral ischemic/reperfusion injury. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19332079 Therapeutic Potential of Non-Psychotropic Cannabidiol in Ischemic Stroke (full 2010) http://www.mdpi.com/1424-8247/3/7/2197/pdf Activation of cannabinoid 2 receptors protects against cerebral ischemia by inhibiting neutrophil recruitment. (full 2010) http://www.fasebj.org/content/24/3/788.long The Multiplicity of Action of Cannabinoids: Implications for Treating Neurodegeneration. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20875047 The cannabinoid WIN55212-2 promotes neural repair after neonatal hypoxia-ischemia. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/21115947 The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxicischemic brain damage in mice is mediated by CB(2) and adenosine receptors. (abst 2010)
Targeting the Endocannabinod System to Limit Myocardial and Cerebral Ischemic and Reperfusion Injury. (abst 2011)
Cannabidiol reduces brain damage and improves functional recovery after acute hypoxiaischemia in newborn pigs. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21654550 Residual effects of focal brain ischaemia upon cannabinoid CB(1) receptor density and functionality in female rats. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21145311 Cerebroprotective effects of TAK-937, a cannabinoid receptor agonist, on ischemic brain damage in middle cerebral artery occluded rats and non-human primates. (abst 2012)
611
Cannabinoid type 2 receptor activation downregulates stroke-induced classic and alternative brain macrophage/microglial activation concomitant to neuroprotection. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/22020035 The Cannabinoid WIN 55212-2 Mitigates Apoptosis and Mitochondrial Dysfunction After Hypoxia Ischemia. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/21909954
TAK SERIES synthetic cannabinoids TAK-875 Takeda moves potential first-in-class diabetes drug into phase III (news 2011)
TAK-937- synthetic CB1 & CB2 agonist Cerebroprotective effects of TAK-937, a cannabinoid receptor agonist, on ischemic brain damage in middle cerebral artery occluded rats and non-human primates. (abst 2012)
TASTE - also see APPETITE STIMULANT Overeating, Alcohol and Sucrose Consumption Decrease in Cb1 Receptor Deleted Mice. (abst 2004)
(full - 2009)
Enhanced Sweet Taste: Endocannabinoids Act Directly on Tongue Taste Receptors (news - 2009) http://www.sciencedaily.com/releases/2009/12/091222104920.htm
612
Chemicals in pot stimulate tongue receptors to taste sweetness.
(news - 2009)
http://www.thefreelibrary.com/Chemicals+in+pot+stimulate+tongue+receptors+to+taste+sweetness.a0215089160
Modulation of sweet taste sensitivity by orexigenic and anorexigenic factors. (full 2010) http://www.jstage.jst.go.jp/article/endocrj/57/6/467/_pdf Reciprocal modulation of sweet taste by leptin and endocannabinoids.
(abst 2010)
Endocannabinoid Modulation Of Tongue Sweet Taste Receptors May Help Control Feeding Behavior (news 2010) http://www.medicalnewstoday.com/releases/174683.php Sweet taste and (AAT)12 repeat in the cannabinoid receptor gene in obese females (letter 2011) http://www.jstage.jst.go.jp/article/endocrj/58/4/323/_pdf Ingredient in cannabis restores taste for cancer patients (news 2011)
Cannabis Ingredient Can Help Cancer Patients Regain Their Appetites and Sense of Taste, Study Finds (news 2011)
TAXONOMY/ GENETICS OF CANNABIS Cannabinoid Phenotypes in Cannabis sativa (abst - 1973)

http://www.nature.com/nature/journal/v245/n5421/abs/245147a0.html
Cannabinoid patterns in seedlings of Cannabis sativa L. and their use in the determination of chemical race. (abst 1977) http://www.ncbi.nlm.nih.gov/pubmed/19599 Cannabinoid level in the leaves as a tool for the early discrimination of cannabis chemiovariants (abst - 1984)
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T6W-4C3C6JF5&_user=10&_origUdi=B6TH7-42WPSNF37&_fmt=high&_coverDate=01%2F31%2F1984&_rdoc=1&_orig=article&_acct=C000050221&_version =1&_urlVersion=0&_userid=10&md5=26ab3ca7038dff6b314c88d4b81f04bd
Identification of a New Chemotype in Cannabis sativa: Cannabigerol - Dominant Plants, Biogenetic and Agronomic Prospects (abst 1987)
Histochemical detection of hemp trichomes and their correlation with the THC content. (abst - 1988)
613
A Male-associated Dna Sequence in a Dioecious Plant, Cannabis Sativa L. (abst 1995)

http://medical-journals.healia.com/doc/8589931/A-male-associated-DNA-sequence-in-a-dioecious-plantCannabis-sativa-L
Boys and Girls Come Out to Play: The Molecular Biology of Dioecious Plants (full - 2000)
http://aob.oxfordjournals.org/cgi/reprint/86/2/211?maxtoshow=&hits=80&RESU`LTFORMAT=&fulltext= cannabis&searchid=1&FIRSTINDEX=1440&resourcetype=HWCIT

(full - 2000)
THC (TETRAHYDROCANNABINOL) ACCUMULATION IN GLANDS OF CANNABIS (CANNABACEAE) (full - 2001)

http://www.hempreport.com/issues/17/malbody17.html
The inheritance of chemical phenotype in Cannabis sativa L.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462421/pdf/12586720.pdf
(full - 2002)
An overview of DNA methods for the identification and individualization of marijuana. (full - 2003) http://www.cmj.hr/2003/44/3/12808725.pdf The Gene Controlling Marijuana Psychoactivity : MOLECULAR CLONING AND HETEROLOGOUS EXPRESSION OF 1-TETRAHYDROCANNABINOLIC ACID SYNTHASE FROM CANNABIS SATIVA L. (full - 2004)
A chemotaxonomic analysis of cannabinoid variation in Cannabis (Cannabaceae) (full 2004) http://www.amjbot.org/content/91/6/966.full The gene controlling marijuana psychoactivity: molecular cloning and heterologous expression of Delta1-tetrahydrocannabinolic acid synthase from Cannabis sativa L. (full 2004) http://www.jbc.org/content/279/38/39767.long A chemotaxonomic analysis of terpenoid variation in Cannabis
(abst - 2004)
RAPD markers encoding retrotransposable elements are linked to the male sex in Cannabis sativa L. (full 2005)
Tetrahydrocannabinolic acid synthase, the enzyme controlling marijuana psychoactivity, is secreted into the storage cavity of the glandular trichomes. (abst 2005)
614
DNA polymorphisms in the tetrahydrocannabinolic acid (THCA) synthase gene in drugtype and fiber-type Cannabis sativa L. (abst - 2006)
History of Cannabis and Its Preparations in Saga, Science and Sobriquet

http://www3.interscience.wiley.com/cgi-bin/fulltext/115806128/PDFSTART
(full - 2007)
Cannabidiolic-acid synthase, the chemotype-determining enzyme in the fiber-type Cannabis sativa. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17544411 Phytochemical and genetic analyses of ancient cannabis from Central Asia (full - 2008)
http://jxb.oxfordjournals.org/cgi/content/full/59/15/4171
DNA polymorphism detection of Cannabis using amplified fragment length polymorphism (abst - 2008)
http://www.unboundmedicine.com/medline/ebm/record/18979914/abstract/%5BDNA_polymorphism_dete ction_of_Cannabis_using_amplified_fragment_length_polymorphism%5D
Genetic individualization of Cannabis sativa by a short tandem repeat multiplex system (abst - 2008)
http://www.unboundmedicine.com/medline/ebm/record/19066867/abstract/Genetic_individualization_of_C annabis_sativa_by_a_short_tandem_repeat_multiplex_system_
Identification of candidate genes affecting 9-tetrahydrocannabinol biosynthesis in Cannabis sativa (full - 2009)
US Patent Application 20090324797 - MODULATING PLANT OIL LEVELS (full 2009) http://www.patentstorm.us/applications/20090324797/fulltext.html Assessment of Cannabinoids Content in Micropropagated Plants of Cannabis sativa and Their Comparison with Conventionally Propagated Plants and Mother Plant during Developmental Stages of Growth. (abst - 2009)
Assessment of the Genetic Stability of Micropropagated Plants of Cannabis sativa by ISSR Markers. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19637112/abstract/Assessment_of_the_Genetic_St ability_of_Micropropagated_Plants_of_Cannabis_sativa_by_ISSR_Markers_
Hemp And Marijuana: Genes Producing THC, Active Ingredient In Cannabis Plant, Identified (news - 2009) http://www.sciencedaily.com/releases/2009/09/090915113538.htm Genes producing tetrahydrocannabinol in marijuana identified (news - 2009)
http://www.news-medical.net/news/20090916/Genes-producing-tetrahydrocannabinol-in-marijuanaidentified.aspx
615
Characteristics of Cannabis sativa L.: seed morphology, germination and growth characteristics, and distinction from Hibiscus cannabinus L (full - 2010)
http://www.jstage.jst.go.jp/article/yakushi/130/2/130_237/_article
In silicio expression analysis of PKS genes isolated from Cannabis sativa L. (full 2010)
Genetic Identification of Female Cannabis sativa Plants at Early Developmental Stage (abst - 2010) https://www.thieme-c onnect.de/DOI/DOI?10.1055/s-0030-1249978 The results of an experimental indoor hydroponic Cannabis growing study, using the 'Screen of Green' (ScrOG) method-Yield, tetrahydrocannabinol (THC) and DNA analysis. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20462712 Metabolic fingerprinting of Cannabis sativa L., cannabinoids and terpenoids for chemotaxonomic and drug standardization purposes. (abst 2010)
A real-time PCR assay for the relative quantification of the tetrahydrocannabinolic acid (THCA) synthase gene in herbal Cannabis samples (abst 2011)
Assessment of the genetic stability of micropropagated plants of Cannabis sativa by ISSR markers. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/19637112 The draft genome and transcriptome of Cannabis sativa.
http://genomebiology.com/content/pdf/gb-2011-12-10-r102.pdf
(full - 2011)
Characteristics of cannabinoids composition of Cannabis plants grown in Northern Thailand and its forensic application. (abst 2011)
Investigations into the Hypothesis of Transgenic Cannabis

(abst 2011)
Medicinal Genomics Sequences the Cannabis Genome to Assemble the Largest Known Gene Collection of this Therapeutic Plant. (news 2011)
http://www.thefreelibrary.com/Medicinal+Genomics+Sequences+the+Cannabis+Genome+to+Assemble+th e...-a0264585240
Cannabis Sequencing Study Explores Differences Between Marijuana, Hemp Producing Plants (news 2011)
http://www.genomeweb.com/sequencing/cannabis-sequencing-study-explores-differences-betweenmarijuana-hemp-producing
616
TEA AS MEDICINE Concentration of Marijuana Metabolites in the Urine After Ingestion of Hemp Seed Tea. (abst - 1999)
(news - 2006) (abst - 2007)
Cannabis tea revisited: A systematic evaluation
TEETH /DENTISTRY HEMP AS A MEDICAMENT : Therapeutic results in stomatology

(full - 1955)
Emotional response to intravenous delta9tetrahydrocannabinol during oral surgery. (abst 1976) http://www.ncbi.nlm.nih.gov/pubmed/1062533 A study of the effect of delta 9-tetrahydrocannabinol (delta 9-THC) on mammalian salivary flow. (abst - 1978)
Illicit drugs for toothache
(letter - 2002) (full - 2006)
http://www.nature.com/bdj/journal/v192/n3/full/4801311a.html
Endocannabinoid, anandamide in gingival tissue regulates the periodontal inflammation through NF-kappaB pathway inhibition. (abst 2006)
Comments on a home remedy for Abcessed Tooth.

http://www.myhomeremedies.com/remedy.cgi?remedyid=4638
(forum - 2007)
Activation of CB2 cannabinoid receptors: a novel therapeutic strategy to accelerate osseointegration of dental implants. (abst - 2009)
617
Cannabis use and destructive periodontal diseases among adolescents
(abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19236530/abstract/Cannabis_use_and_destructive_ periodontal_diseases_among_adolescents_
Cannabis relieves Toothache pain?
(anecdotal - 2009) (abst - 2010)
http://www.freshherbguru.com/2009/07/cannabis-relieves-toothache-pain.html
Involvement of the endocannabinoid system in periodontal healing.

Behavioral effects of pulp exposure in mice lacking cannabinoid receptor 2. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/22152627
THC/ TETRAHYDROCANNABINOL CB1 & 2 agonist STUDIES ON THE PHARMACOLOGY AND ACUTE TOXICITY OF COMPOUNDS WITH MARIHUANA ACTIVITY (abst - 1946)
Chemical basis of hashish activity.
(abst - 1970)
Some actions of delta-1 tetrahydrocannabinol and cannabidiol at cholinergic junctions. (full 1971) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1703324/pdf/brjpharm00552-0217.pdf Activity of Dgr8-and Dgr9-Tetrahydrocannabinol and Related Compounds in the Mouse (abst - 1971)
http://www.sciencemag.org/cgi/content/abstract/172/3979/165?maxtoshow=&hits=80&RESULTFORMAT =&fulltext=marihuana&searchid=1&FIRSTINDEX=2240&resourcetype=HWCIT
A metabolic interaction in vivo between cannabidiol and 1-tetrahydrocannabinol (full - 1972) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1666148/?tool=pubmed Water-soluble derivatives of 1 -tetrahydrocannabinol.
(abst- 1972) (full - 1973)
Effect of Biogenic Amines and Cannabinoids on Bacterial Chemotaxis

Effects of marihuana in laboratory animals and in man
(full - 1974)
618
A pilot study of orally administered 1-trans-tetrahydrocannabinol in the management of patients undergoing radiotherapy for carcinoma of the bronchus (full - 1974)
Smoked marijuana and oral delta-9-THC on specific airway conductance in asthmatic subjects (full - 1974) http://www.ukcia.org/research/SmokedAndOralInAsthmatic.php Acute effects of smoked marijuana and oral delta9-tetrahydrocannabinol on specific airway conductance in asthmatic subjects. (abst - 1974)
Interactions in man of delta-9-tetrahydrocannabinol. II. Cannabinol and cannabidiol. (abst 1975) http://www.ncbi.nlm.nih.gov/pubmed/1097148 Effects of smoked marijuana in experimentally induced asthma. (abst - 1975)
Absence of interaction between delta9-tetrahydrocannabinol (delta-THC) and cannabidiol (CBD) in aggression, muscle control and body temperature experiments in mice. (abst 1975) http://www.ncbi.nlm.nih.gov/pubmed/1171491 The influence of delta9-tetrahydrocannabinol, cannabinol and cannabidiol on tissue oxygen consumption. (abst 1975) http://www.ncbi.nlm.nih.gov/pubmed/1197914 Analgesic effect of delta-9-tetrahydrocannabinol. (abst - 1975) (abst - 1975) (abst - 1976)
The analgesic properties of delta-9-tetrahydrocannabinol and codeine.

Bronchodilator effect of delta1-tetrahydrocannabinol administered by aerosol of asthmatic patients. (full - 1976)

In vivo effects of cannabinoids on macromolecular biosynthesis in Lewis lung carcinomas. (abst - 1977) http://www.ncbi.nlm.nih.gov/pubmed/616322
619
Bronchial effects of aerosolized delta 9-tetrahydrocannabinol in healthy and asthmatic subjects. (abst - 1977)
Delta-9-Tetrahydrocannibinol as an Antiemetic in Cancer Patients Receiving High-Dose Methotrexate (full - 1979) http://www.medmjscience.org/Pages/science/chang.html Cannabinoids. II. Cardiovascular Effects (full - 1980)

(abst - 1980)
Sedative activity of cannabis in relation to its delta'-trans-tetrahydrocannabinol and cannabidiol content. (full -1981)
Activity of cannabis in relation to its delta'-trans-tetrahydro-cannabinol content. (full - 1981) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2071597/?tool=pmcentrez&page=1 The seed and the soil: effect of dosage, personality and starting state on the response to delta 9 tetrahydrocannabinol in man. (full 1981)
Comparison of effects of marihuana cigarettes of three different potencies

http://www.nature.com/clpt/journal/v31/n5/pdf/clpt198286a.pdf
(full - 1982)

Multiple-Drop Study of Topically Applied 1% {Delta}9-Tetrahydrocannabinol in Human Eyes (full - 1983)

http://archopht.amaassn.org/cgi/reprint/101/4/591?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid= 1&FIRSTINDEX=2800&resourcetype=HWCIT
620
Neurobehavioral actions of cannabichromene and interactions with delta 9tetrahydrocannabinol. (abst - 1983) http://www.ncbi.nlm.nih.gov/pubmed/6301931 Respiratory and cardiovascular depressant effects of nabilone, N-methyllevonantradol and delta 9-tetrahydrocannabinol in anesthetized cats. (abst - 1983)
Allergenic properties of naturally occurring cannabinoids.

(abst - 1983)
Acute Effects of Natural and Synthetic Cannabis Compounds on Prolactin Levels in Human Males. (abst 1984) http://www.ncbi.nlm.nih.gov/pubmed/6320226 Intraocular pressure, ocular toxicity and neurotoxicity after administration of delta 9tetrahydrocannabinol or cannabichromene. (abst 1984)
Ocular hypotension, ocular toxicity, and neurotoxicity in response to marihuana extract and cannabidiol. (abst 1984) http://www.ncbi.nlm.nih.gov/pubmed/6098513 Inhibition of neuroblastoma adenylate cyclase by cannabinoid and nantradol compounds (abst 1984) http://www.ncbi.nlm.nih.gov/pubmed/6090851 The quasi-morphine withdrawal syndrome: effect of cannabinol, cannabidiol and tetrahydrocannabinol. (abst - 1985)
The effect of delta-9-THC on human spasticity.
(abst - 1986)
Oral vs. Inhaled Cannabinoids for Nausea/Vomiting from Cancer Chemotherapy (full - 1988) http://www.medmjscience.org/Pages/science/pierson.html The inhibitory effects of cannabinoids, the active constituents of Cannabis sativa L. on human and rabbit platelet aggregation. (abst - 1989)
Marijuana Smoking: Factors That Influence the Bioavailability of Tetrahydrocannabinol (full - 1990) http://www.ukcia.org/research/FactorsThatInfluenceBioavailability.pdf A comparison of the ocular and central effects of delta 9-tetrahydrocannabinol and cannabigerol. (abst - 1990) http://www.ncbi.nlm.nih.gov/pubmed/1965836
621
Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects in a single case double-blind trial. (abst - 1990)
Chronic Exposure to Delta 9-tetrahydrocannabinol Fails to Irreversibly Alter Brain Cannabinoid Receptors. (abst - 1991)
Cannabinoid receptor agonists inhibit Ca current in NG108-15 neuroblastoma cells via a pertussis toxin-sensitive mechanism. (full - 1992)
Effects of delta 9-THC on marijuana smoking, dose choice, and verbal report of drug liking. (full - 1994) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1334408/?tool=pubmed Interactions between delta 9-tetrahydrocannabinol and kappa opioids in mice. (abst - 1994)
http://jpet.aspetjournals.org/content/268/3/1381.abstract?maxtoshow=&hits=80&RESULTFORMAT=&ful ltext=marihuana&searchid=1&FIRSTINDEX=1840&resourcetype=HWCIT
NTP Technical Report on the Toxicology and Carcinogenesis Studies of 1-Trans-Delta9Tetrahyrdocannabinol (CAS No. 1972-08-3) in F344/N Rats and B6C3F1 Mice (Gavage Studies) (full - 1996) http://www.druglibrary.org/Schaffer/hemp/Trans-Delta%20Report.pdf The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity : a pilot study with 2 patients. (abst - 1996)
Toxicity and Carcinogenicity of {Delta}9-Tetrahydrocannabinol in Fischer Rats and B6C3F1 Mice (abst - 1996)
http://toxsci.oxfordjournals.org/cgi/content/abstract/30/1/109?maxtoshow=&hits=80&RESULTFORMAT= &fulltext=marihuana&searchid=1&FIRSTINDEX=240&resourcetype=HWCIT
Genetic differences in delta 9-tetrahydrocannabinol-induced facilitation of brain stimulation reward as measured by a rate-frequency curve-shift electrical brain stimulation paradigm in three different rat strains. (abst 1996)
622
The perceived effects of smoked cannabis on patients with multiple sclerosis. (abst - 1997) http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=13 Study: THC Not Cancer-Causing (news - 1997)
http://www.ukcia.org/research/cancer.php
Cannabidiol and ()9-tetrahydrocannabinol are neuroprotective antioxidants (full - 1998)


(abst - 1998) (letter - 1999) (abst 1999)
Treatment of Tourette's Syndrome With Delta-9-Tetrahydrocannabinol

http://ajp.psychiatryonline.org/cgi/content/full/156/3/495

Cannabis: Discrimination of "Internal Bliss"?
(abst 1999)
http://medical-journals.healia.com/doc/10515300/Cannabis-discrimination-of-internal-bliss
Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. (full - 2000)

(full - 2000) (full - 2000)

GC-MS analysis of the total delta9-THC content of both drug- and fiber-type cannabis seeds. (abst 2000) http://www.ncbi.nlm.nih.gov/pubmed/11110027 Cannabinoids in clinical practice. (abst - 2000)
Tetrahydrocannabinol for treatment of chronic pain
(abst - 2001)
623
Neuroprotection by Delta 9-Tetrahydrocannabinol, the Main Active Compound in Marijuana, against Ouabain-Induced In Vivo Excitotoxicity (abst - 2001)
http://www.jneurosci.org/cgi/content/abstract/21/17/6475?maxtoshow=&hits=10&RESULTFORMAT=&f ulltext=cannabis&andorexactfulltext=and&searchid=1&FIRSTINDEX=70&sortspec=relevance&resourcet ype=HWCIT
Clinical investigation of delta-9-tetrahydrocannabinol (THC) as an alternative therapy for overactive bladders in spinal cord injury (SCI) patients. (abst - 2001)

(abst - 2002) (abst - 2002)
Cannabinoids in the treatment of pain and spasticity in multiple sclerosis.
Treatment of Tourette Syndrome with Delta-9-Tetrahydrocannabinol (Delta9-THC): No Influence on Neuropsychological Performance (full - 2003)
(full - 2003)
Effects of THC on Behavioral Measures of Impulsivity in Humans

(full - 2003)
(full - 2003) http://brain.oxfordjournals.org/cgi/content/full/126/6/1252
624

(full - 2003)
The treatment of spasticity with D9-THC) in patients with spinal cord injury (abst - 2003)
Cannabinoid influences on palatability: microstructural analysis of sucrose drinking after delta(9)-tetrahydrocannabinol, anandamide, 2-arachidonoyl glycerol and SR141716. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12447606 Delta 9-tetrahydrocannabinol (THC) is effective in the treatment of tics in Tourette syndrome: a 6-week randomized trial. (abst - 2003)
Cannabis use for chronic non-cancer pain: results of a prospective survey.

(abst - 2003)
Cannabis can help MS sufferers
(news - 2003)
Differential Effects of THC or CBD-rich Cannabis Extracts on Working Memory in Rats (full - 2004) http://www.ukcia.org/research/THCCBDWorkingMemory.pdf Cannabinoids: Defending the Epileptic Brain (full - 2004)
Initial experiences with medicinal extracts of cannabis for chronic pain: Results from 34 N of 1 studies (full - 2004) http://www.ukcia.org/research/InitialExperiencesChronicPain.pdf The good and the bad effects of () trans-delta-9-tetrahydrocannabinol (9-THC) on humans (abst - 2004)
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TCS-4CSG2C42&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlV ersion=0&_userid=10&md5=99df29b0ce94c395c01f5aad8825d28b
Very low doses of delta 8-THC increase food consumption and alter neurotransmitter levels following weight loss. (abst 2004) http://www.ncbi.nlm.nih.gov/pubmed/15099912 Effect of Delta-9-tetrahydrocannabinol and cannabidiol on nocturnal sleep and earlymorning behavior in young adults. (abst - 2004)
THC in marijuana may block the spread of forms of cancer causing herpes viruses (news - 2004) http://www.news-medical.net/news/2004/09/22/4990.aspx Cannabis truly helps multiple sclerosis sufferers (news - 2004)
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Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice (full - 2005) http://www.nature.com/nature/journal/v434/n7034/full/nature03389.html Synergistic Interactions between Cannabinoids and Environmental Stress in the Activation of the Central Amygdala (full - 2005)
Protective effects of 9-tetrahydrocannabinol against N-methyl-D-aspartate-induced AF5 cell death (full - 2005) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1824211/?tool=pmcentrez The effects of 9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide (full - 2005)
Cannabis may help keep arteries clear
(news - 2005) (news - 2005) (news - 2005)
http://www.newscientist.com/article/mg18624956.000

Science: THC slows development of atherosclerosis in animal study Cannabis Spray for Bipolar (news - 2005) (news - 2005)
THC effective in appetite and weight loss in severe lung disease (COPD)
(news - 2005)
New Synthetic Delta-9-THC Inhaler Offers Safe, Rapid Delivery , Phase I Study (news - 2005) http://www.medicalnewstoday.com/articles/22937.php A tale of two cannabinoids:The therapeutic rationale for combining tetrahydrocannabinol and cannabidiol. (full - 2006)
Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled clinical trial from the Cannabis-InCachexia-Study-Group (full - 2006) http://jco.ascopubs.org/content/24/21/3394.long A Molecular Link between the Active Component of Marijuana and Alzheimers Disease Pathology (full - 2006)
http://www.ukcia.org/research/AlzheimersDiseasePathology.pdf
626
{Delta}9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer Cells through Cdc2 Regulation (full - 2006)
9-Tetrahydrocannabinol-Induced Apoptosis in Jurkat Leukemia T Cells Is Regulated by Translocation of Bad to Mitochondria (full - 2006)
http://mcr.aacrjournals.org/content/4/8/549.full
Further Characterization of the Time-Dependent Vascular Effects of 9Tetrahydrocannabinol (full - 2006) http://jpet.aspetjournals.org/content/317/1/428.full Cannabinoids and the Endocannabinoid System (full - 2006)
Differential effects of cannabis extracts and pure plant cannabinoids on hippocampal neurones and glia. (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16997463?dopt=Abstract Delta-9-THC based monotherapy in fibromyalgia patients on experimentally induced pain, axon reflex flare, and pain relief (abst - 2006)
A pilot clinical study of Delta(9)-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme. (abst - 2006)
Delta(9)-Tetrahydrocannabinol protects hippocampal neurons from excitotoxicity (abst - 2006)

http://www.unboundmedicine.com/medline/ebm/record/17140550/abstract/Delta_9__Tetrahydrocannabino l_protects_hippocampal_neurons_from_excitotoxicity
The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells. (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16458258 The treatment of spasticity with Delta(9)-tetrahydrocannabinol in persons with spinal cord injury. (abst - 2006)
An Experimental Study of Catechol-O-Methyltransferase Val(158)Met Moderation of Delta-9-Tetrahydrocannabinol-Induced Effects on Psychosis and Cognition (abst - 2006)
http://www.unboundmedicine.com/medline/ebm/record/16936704/abstract/An_Experimental_Study_of_Ca techol_O_Methyltransferase_Val_158_Met_Moderation_of_Delta_9_Tetrahydrocannabinol_Induced_Effe cts_on_Psychosis_and_Cognition
627
Methods evaluating cannabinoid and endocannabinoid effects on gastrointestinal functions. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16506408 THC and prochlorperazine effective in reducing vomiting in women following breast surgery (news - 2006)
THC inhibits primary marker of Alzheimer's disease Cannabis destroys cancer cells
medical.net/news/2006/03/01/16340.aspx
(news - 2006)
(news - 2006) http://www.news-
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219532/?tool=pubmed&itool=EntrezSystem2.PEntrez.Pub med.Pubmed_ResultsPanel.Pubmed_SingleItemSupl.Pubmed_DiscoveryDbLinks&ordinalpos=1
Opioid Antagonism of Cannabinoid Effects: Differences between Marijuana Smokers and Nonmarijuana Smokers (full - 2007)
Anandamide and Delta9-tetrahydrocannabinol directly inhibit cells of the immune system via CB2 receptors. (full - 2007)

(full - 2007)
On the pharmacological properties of Delta9-tetrahydrocannabinol (THC). (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17712813
628
The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat involves the CB(2) cannabinoid receptor. (abst - 2007)
http://www.unboundmedicine.com/medline/ebm/record/17588560/abstract/The_antinociceptive_effect_of_ Delta9_tetrahydrocannabinol_in_the_arthritic_rat_involves_the_CB_2__cannabinoid_receptor

(abst - 2007)
The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17583570 Delta(9)-tetrahydrocannabinol (Delta(9)-THC) prevents cerebral infarction via hypothalamic-independent hypothermia. (abst - 2007)
Symptomatic treatment of multiple sclerosis using cannabinoids: recent advances. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17868014 Medicinal chemistry endeavors around the phytocannabinoids.
(abst - 2007)
Effects of a Selective Cannabinoid Agonist and Antagonist on Body Temperature in Rats (abst - 2007)
Pot's Active Ingredient Halts Lung Cancer Growth, Study Says

(news - 2007) (news - 2007)
Cannabis can reduce Allergic Skin Reactions, latest research shows
http://www.healthjockey.com/2007/06/08/cannabis-can-reduce-allergic-skin-reactions-latest-researchshows/
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9-Tetrahydrocannabinol Content of Commercially Available Hemp Products (full - 2008) https://secure.manitobaharvest.com/images/uploads/pages/File/thc_study_jat_2008.pdf Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of 9-tetrahydrocannabinol (full - 2008)
(full - 2008)
Cannabinoid receptors in acute and chronic complications of atherosclerosis (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219535/?tool=pmcentrez Antibacterial cannabinoids from Cannabis sativa: a structure-activity study. (full - 2008)
Delta-9-tetrahydrocannabinol pharmacokinetics
(abst - 2008)
High concentrations of cannabinoids activate apoptosis in human U373MG glioma cells. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18615640 Effect of intrapulmonary tetrahydrocannabinol administration in humans. (abst - 2008)
Science: THC reduces reflux of acid from the stomach
(news 2008)
Delta 9-tetrahydrocannabinol induces dopamine release in the human striatum. (full - 2009) http://www.nature.com/npp/journal/v34/n3/full/npp2008138a.html Cannabinoids 9-Tetrahydrocannabinol and Cannabidiol Differentially Inhibit the Lipopolysaccharide-activated NF-B and Interferon-/STAT Proinflammatory Pathways in BV-2 Microglial Cells (full 2009)
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Hydroxylation and Further Oxidation of 9-Tetrahydrocannabinol by Alkane-Degrading Bacteria (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786519/?tool=pmcentrez Cannabinoids, Endocannabinoids, and Related Analogs in Inflammation (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664885/?tool=pubmed Evaluation of Prevalent Phytocannabinoids in the Acetic Acid Model of Visceral Nociception (full 2009)
Actions of delta-9-tetrahydrocannabinol in cannabis
(full - 2009)
Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma (full - 2009) http://mct.aacrjournals.org/content/8/7/1838.full TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action. (full 2009)
Cannabinoid action induces autophagymediated cell death through stimulation of ER stress in human glioma cells. (abst - 2009)
Neurocognitive performance during acute THC intoxication in heavy and occasional cannabis users. (abst - 2009)
Cannabidiol reverses the reduction in social interaction produced by low dose Delta(9)tetrahydrocannabinol in rats. (abst 2009) http://www.ncbi.nlm.nih.gov/pubmed/19393686 Active cannabis chemicals halt prostate cancer cell growth (news - 2009)
http://www.news-medical.net/news/20090908/Active-cannabis-chemicals-halt-prostate-cancer-cellgrowth.aspx
631

(news - 2009)
THC initiates brain cancer cells to destroy themselves
(news - 2009)
http://www.worldhealth.net/news/thc_initiates_brain_cancer_cells_to_dest/
Active Component Of Marijuana Has Anti-Cancer Effects, Study Suggests (news - 2009) http://www.sciencedaily.com/releases/2009/04/090401181217.htm Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis (full - 2010)
Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917429/?tool=pmcentrez Smoked cannabis for chronic neuropathic pain: a randomized controlled trial (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950205/?tool=pmcentrez Therapeutical use of the cannabinoids in psychiatry
(full 2010)

Cannabinoids Inhibit Cellular Respiration of Human Oral Cancer Cells

(full - 2010)
Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19896326
632
Modulation of Adipocyte Biology by 9-Tetrahydrocannabinol

http://www.nature.com/oby/journal/vaop/ncurrent/abs/oby2010100a.html
(abst - 2010)
The dual effects of delta(9)-tetrahydrocannabinol on cholangiocarcinoma cells: antiinvasion activity at low concentration and apoptosis induction at high concentration. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/19916793 Exposure to a high-fat diet decreases sensitivity to 9-tetrahydrocannabinol-induced motor effects in female rats (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20850461 Chronic cannabinoid administration lowers viral replication in lymph nodes of SIV infected Rhesus macaques (abst - 2010)
Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20884951 THC Prevents MDMA Neurotoxicity in Mice.
(abst - 2010)
Cannabinoid receptor 1 binding activity and quantitative analysis of Cannabis sativa L. smoke and vapor. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20118579 Opposite Effects of -9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology (abst - 2010)
Disposition of Cannabichromene, Cannabidiol, and 9-Tetrahydrocannabinol and its Metabolites in Mouse Brain following Marijuana Inhalation Determined by HighPerformance Liquid Chromatography-Tandem Mass Spectrometry (abst - 2010)
Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20884951 Oral Delta 9-tetrahydrocannabinol improved refractory Gilles de la Tourette syndrome in an adolescent by increasing intracortical inhibition: a case report. (abst - 2010)
633
Pharmacological evaluation of the natural constituent of Cannabis sativa, cannabichromene and its modulation by 9-tetrahydrocannabinol (abst - 2010)
(abst - 2010)
Tocolytic Effect of 9-Tetrahydrocannabinol in Mice Model of Lipopolysaccharide Induced Preterm Delivery: Role of Nitric Oxide (abst - 2010)
http://rsx.sagepub.com/content/17/4/391.abstract
Key ingredient staves off marijuana memory loss
(news - 2010)
Marijuana May Extend Life Expectancy Of Lou Gehrig's Disease Patients, Study Says (news - 2010) http://www.norml.org/index.cfm?Group_ID=8191 THC Keeps Monkeys Alive in AIDS Research Model (news - 2010)
http://cannabination.com/2010/10/23/thc-keeps-monkeys-alive-in-aids-research-model/
Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa (full 2011) http://www.jstage.jst.go.jp/article/bpb/34/5/774/_pdf Delta-9-tetrahydrocannabinol may palliate altered chemosensory perception in cancer patients: results of a randomized, double-blind, placebo-controlled pilot trial (full 2011) http://annonc.oxfordjournals.org/content/early/2011/02/11/annonc.mdq727.full Cannabinoid Neuroimmune Modulation of SIV Disease. (abst 2011)
Cannabidiol potentiates (9)-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21667074 Prospects for cannabinoid therapies in basal ganglia disorders. (abst 2011)
634
Combined effects of THC and caffeine on working memory in rats. (abst 2011)
Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. (abst - 2011) http://www.ncbi.nlm.nih.gov/pubmed/21749363 (9)-THC and WIN55,212-2 affect brain tissue levels of excitatory amino acids in a phenotype-, compound-, dose-, and region-specific manner (abst 2011)

Plasma cannabinoid pharmacokinetics following controlled oral delta9tetrahydrocannabinol and oromucosal cannabis extract administration (abst 2011)
Pharmacokinetics of a combination of 9-tetrahydro-cannabinol and celecoxib in a porcine model of hemorrhagic shock. (abst 2011)
Pre- and post-conditioning treatment with an ultra-low dose of 9-tetrahydrocannabinol (THC) protects against pentylenetetrazole (PTZ)-induced cognitive damage. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21315768
635
Heterogeneity in the composition of marijuana seized in California.
(abst 2011)
Modulation of Auditory and Visual Processing by Delta-9-Tetrahydrocannabinol and Cannabidiol: an fMRI Study. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21412224 Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. (abst 2011)
Ingredient in cannabis restores taste for cancer patients Marijuana Compound Treats Multiple Health Issues
http://www.foxnews.com/health/2010/03/10/cannabis-deficient/
(news 2011) (news 2011)
Another Study Confirms Anti-Cancer Effects of THC and CBD (news 2011)
THC ACID/ THCA - non-psychoactive precursor of THC The gene controlling marijuana psychoactivity: molecular cloning and heterologous expression of Delta1-tetrahydrocannabinolic acid synthase from Cannabis sativa L. (full 2004) http://www.jbc.org/content/279/38/39767.long Crystallization of 1-tetrahydrocannabinolic acid (THCA) synthase from Cannabis sativa (full - 2005) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1952348&tool=pmcentrez Unheated Cannabis sativa extracts and its major compound THC-acid have potential immuno-modulating properties not mediated by CB1 and CB2 receptor coupled pathways. (abst - 2006)
THC inhibits primary marker of Alzheimer's disease
(news - 2006)
Identification and Characterization of Cannabinoids That Induce Cell Death through Mitochondrial Permeability Transition in Cannabis Leaf Cells (full 2007)
http://www.jbc.org/content/282/28/20739.full?sid=a5db98db-ff96-4187-8790-57097bbe15c1
Production of THC acid by the biosynthetic enzyme secreted from transgenic Pichia pastoris. (abst - 2007) http://marijuana.researchtoday.net/archive/4/8/1331.htm
636
Cannabinoids act as necrosis-inducing factors in Cannabis sativa
(full - 2008)
Evaluation of Prevalent Phytocannabinoids in the Acetic Acid Model of Visceral Nociception (full 2009)
A real-time PCR assay for the relative quantification of the tetrahydrocannabinolic acid (THCA) synthase gene in herbal Cannabis samples (abst 2011)
Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa (full 2011) http://www.jstage.jst.go.jp/article/bpb/34/5/774/_pdf Immunochemical approach using monoclonal antibody against (9)tetrahydrocannabinolic acid (THCA) to discern cannabis plants and to investigate new drug candidates. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21143135/abstract/Immunochemical_approach_usi ng_monoclonal_antibody_against_%CE%94_9__tetrahydrocannabinolic_acid__THCA__to_discern_canna bis_plants_and_to_investigate_new_drug_candidates_
TETRAHYDROCANNABINOL-HEMISUCCINATE / THC-HS US Patent 5389375 - Stable suppository formulations effecting bioavailability of 9 -thc (full - 1995) http://www.patentstorm.us/patents/5389375/fulltext.html US Patent 5508037 - Stable suppository formulations effecting bioavailability of 9 THC (full - 1996) http://www.patentstorm.us/patents/5508037/fulltext.html The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity: a pilot study with 2 patients. (abst - 1996)
Chemical Stabilization of a Delta9-Tetrahydrocannabinol Prodrug in Polymeric Matrix Systems Produced by a Hot-melt Method: Role of Microenvironment pH (full - 2006)
http://www.aapspharmscitech.org/view.asp?art=pt070371
637
Preparation and characterization of inclusion complexes of a hemisuccinate ester prodrug of delta9-tetrahydrocannabinol with modified beta-cyclodextrins. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20333489/abstract/Preparation_and_characterizatio n_of_inclusion_complexes_of_a_hemisuccinate_ester_prodrug_of_delta9_tetrahydrocannabinol_with_mod ified_beta_cyclodextrins_
TETRAHYDROCANNABIVARIN/ THCV phytocannabinoid, CB1 & CB2 antagonist Cannabivarin and Tetrahydrocannabivarin, Two New Constituents of Hashish (abst - 1971) http://www.nature.com/nature/journal/v232/n5312/abs/232579a0.html Delta9-tetrahydrocannabivarin as a marker for the ingestion of marijuana versus Marinol: results of a clinical study (abst - 2001)
Plant cannabinoids: a neglected pharmacological treasure trove
(full - 2005)
Non-psychotropic plant cannabinoids:new therapeutic opportunities from an ancient herb (full - 2009 )
638
Delta9-tetrahydrocannabivarin testing may not have the sensitivity to detect marijuana use among individuals ingesting dronabinol. (full - 2010)
The plant cannabinoid Delta9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice. (full 2010)
Delta-Tetrahydrocannabivarin suppresses in vitro epileptiform and in vivo seizure activity in adult rats. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20196794 Anticonvulsant effects of GWP42006 in vitro and in vivo in rat (abst - 2010)
Symptom-relieving and neuroprotective effects of the phytocannabinoid D(9) -THCV in animal models of Parkinson's disease (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21323909/abstract/Symptom_relieving_and_neuro protective_effects_of_the_phytocannabinoid_D_9___THCV_in_animal_models_of_Parkinson%27s_disea se_
Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), (9)-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessivecompulsive behaviour. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21796370 (8) -Tetrahydrocannabivarin protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress and inflammatory response involving CB(2) receptors. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21470208/abstract/%CE%94_8___Tetrahydrocann abivarin_protects_against_hepatic_ischemia/reperfusion_injury_by_attenuating_oxidative_stress_and_infla mmatory_response_involving_CB_2__receptors_
CB(1) -independent mechanisms of (9) -THCV, AM251 and SR141716 (rimonabant). (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21740450 Phytocannabinoids as novel therapeutic agents in CNS disorders
(abst 2011)
Cannabis could help treat epilepsy Cannabis could be used to treat epilepsy
(news 2011) (news 2011)
639
New research provides hope for those with epilepsy

(news - 2011)
TIME PERCEPTION Cannabis, atropine, and temporal information processing.

(abst - 1984) (abst 1998)

Cannabinoid modulation of time estimation in the rat.

(abst 2001)
Marijuana Alters the Human Cerebellar Clock. (abst 2003)

http://medical-journals.healia.com/doc/12821798/Marijuana-alters-the-human-cerebellar-clock
Effects of marijuana on temporal discriminations in humans.

(abst 2006)
Cannabinoid Modulation of Time Estimation in the Rat.

http://content.apa.org/pubmed/bne/115/1/243
(full 2001)
TINNITUS - also see HEARING Drug treatments for subjective tinnitus: serendipitous discovery versus rational drug design. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/16044667 Doctor's diary: cannabis as medicine - the dilemma
(news - 2005)
Dronabinol reduces signs and symptoms of idiopathic intracranial hypertension : a case report (abst + 1st page - 2006)
http://www.liebertonline.com/doi/abs/10.1089/jop.2006.22.68
Cannabinoid receptor down-regulation in the ventral cochlear nucleus in a salicylate model of tinnitus. (abst - 2007) http://www.ncbi.nlm.nih.gov/pubmed/17376618
640
The effects of the synthetic cannabinoid receptor agonists, WIN55,212-2 and CP55,940, on salicylate-induced tinnitus in rats. (abst 2010)
Patterns of use, sequence of onsets and correlates of tobacco and cannabis

(abst 2011)
TOBACCO VS CANNABIS So, you thought it was the tar that caused cancer... (news - no date)

(abst 1980)
Marijuana v.s. Tobacco smoke compositions

http://www.ukcia.org/research/smoke-contents.php
(list - 1988)
Tobacco and marijuana use on offspring growth from birth through 3 years of age. (abst - 1992)

(news - 1994)
High anxieties - What the WHO doesn't want you to know about cannabis (news - 1998)
http://www.newscientist.com/article/mg15721220.200-high-anxieties--what-the-who-doesnt-want-you-toknow-about-cannabis.html
Behavioural and biochemical evidence for interactions between 9-tetrahydrocannabinol and nicotine (full - 2002)
Tobacco and Cannabis Smoking Cessation Can Lead to Intoxication with Clozapine or Olanzapine. (abst 2002)
641
Comparing cannabis with tobaccoagain Link between cannabis and mortality is still not established (full - 2003)
You cant go without a fag . . . you need it for your hasha qualitative exploration of smoking, cannabis and young people (full - 2004)
http://www.ukcia.org/research/YouCantGoWithoutAFag.pdf
Delta9-tetrahydrocannabinol decreases somatic and motivational manifestations of nicotine withdrawal in mice. (abst - 2004)
Cannabis and tobacco smoke are not equally carcinogenic

(full - 2005)
Cigars-for-blunts: choice of tobacco products by blunt smokers. (abst 2005)

Smoking Marijuana Does Not Cause Lung Cancer

(news - 2005)
Cancer Risk from Tobacco Greater than Marijuana Smoking, Researcher Says (news - 2005)
http://www.drugfree.org/join-together/drugs/cancer-risk-from-tobacco-than
Cannabis Smoke Is Less Likely To Cause Cancer Than Tobacco Smoke (news - 2005) http://www.sciencedaily.com/releases/2005/10/051019003339.htm Aluminum in Tobacco and Cannabis and Smoking-Related Disease
(abst - 2006)
Explicit and Implicit Effects of Anti-marijuana and Anti-tobacco Tv Advertisements. (abst 2006) http://www.sciencedirect.com/science/article/pii/S0306460306000955 Marijuana Improves Fertility in Tobacco Smokers (news - 2006)
http://news.softpedia.com/news/Marijuana-Improves-Fertility-in-Tobacco-Smokers-41535.shtml
Marijuana-like Chemical Can Restore Sperm Function Lost to Tobacco Abuse (news - 2006) http://www.rxpgnews.com/specialtopics/article_5093.shtml Some go without a cigarette: characteristics of cannabis users who have never smoked tobacco. (full - 2007) http://archpedi.ama-assn.org/cgi/content/full/161/11/1042 Chronologically overlapping occurrences of nicotine-induced anxiety- and depressionrelated behavioral symptoms: effects of anxiolytic and cannabinoid drugs (full - 2007)
642
A Comparison of Mainstream and Sidestream Marijuana and Tobacco Cigarette Smoke Produced under Two Machine Smoking Conditions (full - 2007)
http://www.ukcia.org/research/ComparisonOfSmoke.pdf
Progression from marijuana use to daily smoking and nicotine dependence in a national sample of U.S. adolescents (abst - 2007)
http://www.erowid.org/references/refs_view.php?ID=6951
Cannabis use when it's legal
(abst - 2007)
Are Cigarettes More of a Drag on Teens than Marijuana?
(news - 2007) (full - 2008)
Cannabinoid Receptor 1 Gene Association With Nicotine Dependence
http://archpsyc.amaassn.org/cgi/content/full/65/7/816?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&se archid=1&FIRSTINDEX=0&resourcetype=HWCIT
Cannabis-based Drugs can help you quit Smoking
(news - 2008) (news - 2008)
http://www.healthjockey.com/2008/03/11/cannabis-based-drugs-can-help-you-quit-smoking/
Report: Marijuana Less Harmful than Alcohol or Tobacco

http://www.drugfree.org/join-together/other/report-marijuana-less
Curing Addiction With Cannabis Medicines? Cannabis Smoke and Cancer: Assessing the Risk
(news - 2008) (news - 2008)
Characteristics of Adolescents Who Use Cannabis But Not Tobacco (news - 2008)
Effects of the cannabinoid CB1 receptor antagonist AM 251 on the reinstatement of nicotine-conditioned place preference by drug priming in rats. (full - 2009)
Comparison of subjective, pharmacokinetic, and physiological effects of marijuana smoked as joints and blunts. (abst - 2009)
643
A comparison of drug use and dependence between blunt smokers and other cannabis users (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19212929/abstract/A_comparison_of_drug_use_an d_dependence_between_blunt_smokers_and_other_cannabis_users_
Cannabis and tobacco use: where are the boundaries? A qualitative study on cannabis consumption modes among adolescents. (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19515745/full_citation/Cannabis_and_tobacco_use :_where_are_the_boundaries_A_qualitative_study_on_cannabis_consumption_modes_among_adolescents _
Effects of cannabis on lung function: a population-based cohort study. (full - 2010)

Disposition of smoked cannabis with high Delta(9)-tetrahydrocannabinol content: A kinetic model. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20450927/abstract/Disposition_of_smoked_cannab is_with_high_Delta_9__tetrahydrocannabinol_content:_A_kinetic_model_
Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition. (full 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227620/?tool=pubmed Adding Tobacco to Cannabis--Its Frequency and Likely Implications. (abst 2011)
The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine-induced dopamine elevations in the nucleus accumbens shell in rats (abst 2011)
Rural adolescent alcohol, tobacco, and illicit drug use: a comparison of students in victoria, australia, and washington state, United States. (abst 2011)
The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine-induced dopamine elevations in the nucleus accumbens shell in rats. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21557729 Why doesnt marijuana cause cancer? (news 2011)
Patterns of blunt use among rural young adult african-american men. (abst 2012)
644
Marijuana Smoke Not as Damaging as Tobacco, Says Study (news - 2012)

TOLERANCE Lack of tolerance to 9 -tetrahydrocannabinol in chimpanzees

(abst - 1973)
Long-Term Use of Marihuana and the Development of Tolerance or Sensitivity to{Delta}9Tetrahydrocannabinol (abst -1974)
http://archpsyc.amaassn.org/cgi/content/abstract/31/1/89?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid &searchid=1&FIRSTINDEX=3040&resourcetype=HWCIT
A Molecular Basis of Analgesic Tolerance to Cannabinoids
(full - 2007)
Blunted Psychotomimetic and Amnestic Effects of -9-Tetrahydrocannabinol in Frequent Users of Cannabis (full 2008)
Role of GLT-1 transporter activation in prevention of cannabinoid tolerance by the betalactam antibiotic, ceftriaxone, in mice. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21536061/abstract/Role_of_GLT_1_transporter_ac tivation_in_prevention_of_cannabinoid_tolerance_by_the_beta_lactam_antibiotic_ceftriaxone_in_mice_
645
Neurophysiological functioning of occasional and heavy cannabis users during THC intoxication. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21975580/abstract/Neurophysiological_functionin g_of_occasional_and_heavy_cannabis_users_during_THC_intoxication_
The schizophrenia susceptibility gene neuregulin 1 modulates tolerance to the effects of cannabinoids. (abst 2011)
TOURETTE'S SYNDROME MARIJUANA AND TOURETTE'S SYNDROME

http://www.druglibrary.org/schaffer/hemp/medical/mjtouret.htm
(letter - 1988) (abst - 1993)
Effective treatment of Tourettes syndrome with marijuana.
http://www.cannabismed.org/studies/ww_en_db_study_show.php?s_id=255&&search_pattern=INTERACTION
Gilles de la Tourette syndrome, influence of nicotine, alcohol, and marijuana on the clinical symptoms (abst - 1997)
http://cel.isiknowledge.com/InboundService.do?product=CEL&action=retrieve&SrcApp=Highwire&UT=0 00071008700009&SID=2FbKfcabFdA3KGAbH1L&Init=Yes&SrcAuth=Highwire&mode=FullRecord&c ustomersID=Highwire
Cannabinoids: possible role in patho-physiology and therapy of Gilles de la Tourette syndrome. (abst - 1998)
Cannabis in movement disorders.
(abst - 1999) (letter - 1999)
Treatment of Tourette's Syndrome With Delta-9-Tetrahydrocannabinol

http://ajp.psychiatryonline.org/cgi/content/full/156/3/495
646
Science: THC in TOURETTE-Syndrome
(news - 1999)
Science/Germany: Clinical study on THC in TOURETTE's syndrome
(news 2000)
Combined Treatment of Tourette Syndrome with Delta-9-THC and Dopamine Receptor Antagonists (full 2002) http://www.cannabis-med.org/data/pdf/2002-03-04-9.pdf Treatment of Tourette's syndrome with Delta 9-tetrahydrocannabinol (THC): a randomized crossover trial. (abst - 2002)
Science: THC effective in TOURETTE-Syndrome (news - 2002)

Treatment of Tourette Syndrome with Delta-9-Tetrahydrocannabinol (Delta9-THC): No Influence on Neuropsychological Performance (full - 2003)
Delta 9-tetrahydrocannabinol (THC) is effective in the treatment of tics in Tourette syndrome: a 6-week randomized trial. (abst - 2003)
Cannabinoids reduce symptoms of Tourette's syndrome.
(abst - 2003) (news - 2003)
http://www.ncbi.nlm.nih.gov/pubmed/14521482?dopt=Abstract&holding=f1000,f1000m,isrctn
Science: THC effective in TOURETTE syndrome in a 6-week trial
Tourette syndrome is not caused by mutations in the central cannabinoid receptor (CNR1) gene. (abst - 2004) http://www.ncbi.nlm.nih.gov/pubmed/15108190 Cannabinoids for Tourette's Syndrome.
(abst - 2009)
Oral Delta 9-tetrahydrocannabinol improved refractory Gilles de la Tourette syndrome in an adolescent by increasing intracortical inhibition: a case report. (abst - 2010)
647
A New Use for Medical Marijuana?
(news - 2010)
http://consults.blogs.nytimes.com/
Cannabinoids improve driving ability in a Tourette's patient.
(news 2011)
TRICHOTILLOMANIA compulsive hair pulling also see OBSESSIVE-COMPULSIVE DISORDER Dronabinol, a cannabinoid agonist, reduces hair pulling in trichotillomania: a pilot study. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21590520/abstract/Dronabinol_a_cannabinoid_ago nist_reduces_hair_pulling_in_trichotillomania:_a_pilot_study_
Science: THC effective in trichotillomania symptoms in a pilot study (news 2011)

TUBERCULOSIS HEMP AS A MEDICAMENT : Importance of hemp seeds in the tuberculosis therapy (Forum thread- full- 1955) (EDEZYME. recipe)
A cluster of tuberculosis associated with use of a marijuana water pipe.

(abst - 2003) (full - 2004)
Tuberculosis Outbreak in Marijuana Users, Seattle, Washington, 2004

http://www.cdc.gov/ncidod/eid/vol12no07/05-1436.htm
(news - 2008)
ULCERATIVE COLITIS - see COLITIS and also BOWEL DISORDERS
648
URB - 597 / KDS-4103- slows cannabinoid destruction Marijuana's Distant Relative May Be The Next Prozac; Chemical Reduces Anxiety Using Novel Nerve System In Body (news - 2002)
Cannabis' Potential Exciting Researchers in Treatment of ALS, Parkinson's Disease URB597 (news - 2004)
Parkinsons' Helped By Marijuana-Lke Chemicals In Brain (news 2007)

Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models (full - 2006)
The CB1 Cannabinoid Receptor Mediates Excitotoxicity-induced Neural Progenitor Proliferation and Neurogenesis (full - 2007) http://www.jbc.org/content/282/33/23892.full The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3'carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice. (full - 2007) http://jpet.aspetjournals.org/content/322/1/236.long Antidepressant-like activity of the fatty acid amide hydrolase inhibitor URB597 in a rat model of chronic mild stress. (abst 2007) http://www.ncbi.nlm.nih.gov/pubmed/17511970 Marijuana Against Parkinson? (news 2007) (news - 2007)
http://news.softpedia.com/news/Marijuana-Against-Parkinson-46701.shtml
Marijuana-Like Brain Chemicals Work As Antidepressant

Enhancing Activity Of Marijuana-Like Chemicals In Brain Helps Treat Parkinson's Symptoms In Mice (news - 2007)
649
The FAAH inhibitor URB-597 ameliorates cannabinoid withdrawal in mice (abst - 2008)
Targeting endocannabinoid degradation protects against experimental colitis in mice: involvement of CB1 and CB2 receptors. (abst 2008)
Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain. (abst - 2009) http://www.ncbi.nlm.nih.gov/pubmed/19502530 Long-term consequences of URB597 administration during adolescence on cannabinoid CB1 receptor binding in brain areas. (abst 2009)
Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition. (full 2011)
Behavioral sequelae following acute diisopropylfluorophosphate intoxication in rats: comparative effects of atropine and cannabinomimetics. (full 2010)
(abst - 2010)
Behavioural and molecular consequences of chronic cannabinoid treatment in Huntington's disease transgenic mice. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20600638/abstract/Behavioural_and_molecular_co nsequences_of_chronic_cannabinoid_treatment_in_Huntington%27s_disease_transgenic_mice_
650
Regulation of nausea and vomiting by cannabinoids . (abst 2011)

URB - 754 -slows cannabinoid destruction The CB1 Cannabinoid Receptor Mediates Excitotoxicity-induced Neural Progenitor Proliferation and Neurogenesis (full - 2007) http://www.jbc.org/content/282/33/23892.full
URB - 973 - slows cannabinoid destruction Compound boosts marijuana-like chemical in the body to relieve pain at injury site (news - 2010) http://www.eurekalert.org/pub_releases/2010-09/uoc--cbm092010.php
VAPORIZERS - see METHODS OF USE- VAPORIZERS
651
VETERINARY USE/ ANIMALS THE RELATIVE ACTIVITY OF VARIOUS PURIFIED PRODUCTS OBTAINED FROM AMERICAN GROWN HASHISH (abst - 1938)
Disposition and bioavailability of various formulations of tetrahydrocannabinol in the rhesus monkey. (abst 1985) http://www.ncbi.nlm.nih.gov/pubmed/2985774 A species comparison of the toxicity of nabilone, a new synthetic cannabinoid. (abst 1987) http://www.ncbi.nlm.nih.gov/pubmed/2888699 Species specificity in the metabolism of nabilone. Relationship between toxicity and metabolic routes. (abst - 1987) http://www.ncbi.nlm.nih.gov/pubmed/3037806 Pharmacokinetics of cannabidiol in dogs. (abst - 1988)
http://dmd.aspetjournals.org/content/16/3/469.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=cannabis&searchid=1&FIRSTINDEX=800&resourcetype=HWCIT
In vitro metabolism of cannabichromene in seven common laboratory animals. (abst 1990) http://www.ncbi.nlm.nih.gov/pubmed/1981514 In vitro metabolism of delta-11-tetrahydrocannabinol in the mouse, rat, guinea pig, rabbit, hamster, gerbil and cat. (abst 1990) http://www.ncbi.nlm.nih.gov/pubmed/2253656 In vitro metabolism of cannabigerol in several mammalian species. (abst 1990)
Behavioral effects of cannabinoid agents in animals.

(abst 1999)
Finding of the endocannabinoid signalling system in Hydra, a very primitive organism: possible role in the feeding response. (abst 1999)

(abst 2002)
The effect of feeding hemp seed meal to laying hens.

(abst 2005)
Evaluation of a Human On-site Urine Multidrug Test for Emergency Use With Dogs (abst - 2009)
http://www.jaaha.org/cgi/content/abstract/45/2/59?maxtoshow=&hits=80&RESULTFORMAT=&fulltext= cannabis&searchid=1&FIRSTINDEX=3200&resourcetype=HWCIT
652
Influence of Feed Supplementation with Cannabis Sativa on Quality of Broilers Carcass (full - 2010) http://www.pvj.com.pk/pdf-files/30_1/34-38.pdf The endocannabinoid 2-arachidonoyl-glycerol controls odor sensitivity in larvae of Xenopus laevis. (full 2010) http://www.jneurosci.org/content/30/26/8965.long Anandamide and AM251, via water, modulate food intake at central and peripheral level in fish. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/19800340 Scientific Opinion on the safety of hemp (Cannabis genus) for use as animal feed (full 2011)
Dietary hempseed meal intake increases body growth and shortens the larval stage via the upregulation of cell growth and sterol levels in Drosophila melanogaster. (abst 2010)
(news - 2010)
Michel Rouyer, French Farmer, Fined After Feeding Ducks Marijuana
(news - 2010)
http://www.huffingtonpost.com/2010/11/22/michel-rouyer-french-farm_n_786973.html#comments
Cannabidiol decreases body weight gain in rats: Involvement of CB2 receptors. (abst - 2011) http://marijuana.researchtoday.net/archive/8/1/3517.htm Cannabis intoxication in three Green iguanas (Iguana iguana). (abst 2011)
Effects of palmitoylethanolamide on the cutaneous allergic inflammatory response in Ascaris hypersensitive Beagle dogs. (abst 2011)
Identification of cannabinoid type 1 receptor in dog hair follicles. (abst 2011)

http://www.unboundmedicine.com/medline/ebm/record/21414652/abstract/Identification_of_cannabinoid_t ype_1_receptor_in_dog_hair_follicles_
Pot patch for your pooch developed in Seattle lab (news 2011)
http://www.king5.com/news/local/A-pot-patch-for-your-pooch-126363118.html
Vets see more dogs snarfing humans medical pot (news 2011)
http://www.durangoherald.com/article/20111218/NEWS01/712189903/Vets-see-more-dogs-snarfinghumans%E2%80%99-medical-pot
653
VISION- also see GLAUCOMA CONJUGATE DEVIATION OF THE EYES AFTER Cannabis indica INTOXICATION* (full - 1964)
Delta 9-tetrahydrocannabinol: elevation of absolute visual thresholds of rabbits. (abst 1979) http://www.ncbi.nlm.nih.gov/pubmed/482306 Physiologic observations in a controlled clinical trial of the antiemetic effectiveness of 5, 10, and 15 mg of delta 9-tetrahydrocannabinol in cancer chemotherapy. Ophthalmologic implications. (abst - 1981)

Mydriasis induced by tetrahydrocannabinol (THC) in rats
(full - 1982)
http://www.iovs.org/cgi/reprint/22/3/408?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuan a&searchid=1&FIRSTINDEX=640&resourcetype=HWCIT
Intraocular pressure, ocular toxicity and neurotoxicity after administration of delta 9tetrahydrocannabinol or cannabichromene. (abst 1984)
Ocular hypotension, ocular toxicity, and neurotoxicity in response to marihuana extract and cannabidiol. (abst 1984) http://www.ncbi.nlm.nih.gov/pubmed/6098513 Intraocular pressure, ocular toxicity and neurotoxicity after administration of cannabinol or cannabigerol. (abst 1984) http://www.ncbi.nlm.nih.gov/pubmed/6499952 Persistent visual changes following hashish consumption.
(full - 1993)
HU-211, a nonpsychotropic cannabinoid, produces short- and long-term neuroprotection after optic nerve axotomy. (abst 1996) http://www.ncbi.nlm.nih.gov/pubmed/8714863 Patent 5631297 - Anandamides useful for the treatment of intraocular hypertension, ophthalmic compositions containing the same and methods of use of the same (full 1997) http://www.patentstorm.us/patents/5631297/fulltext.html Smoking dope restored my sight (news - 1998) http://news.bbc.co.uk/2/hi/health/212301.stm
Effects of synthetic delta9-tetrahydrocannabinol on binocular depth inversion of natural and artificial objects in man. (abst 1999) http://www.ncbi.nlm.nih.gov/pubmed/10208314
654
Cannabinoids' Role In Retinal Function Described

(news - 1999)
Different effects of nabilone and cannabidiol on binocular depth inversion in Man. (abst 2000) http://www.ncbi.nlm.nih.gov/pubmed/10837858 Neuroprotective Effect of()9-Tetrahydrocannabinol and Cannabidiol in N-Methyl-dAspartate-Induced Retinal Neurotoxicity - Involvement of Peroxynitrite (full - 2003)
Dexanabinol (HU-211) has a beneficial effect on axonal sprouting and survival after rat optic nerve crush injury. (abst 2003) http://www.ncbi.nlm.nih.gov/pubmed/12535983 Cannabis improves night vision: a case study of dark adaptometry and scotopic sensitivity in kif smokers of the Rif mountains of northern Morocco (full - 2004)
Cannabidiol Preserves Retinal Neurons and Reduces Vascular Permeability in Experimental Diabetes (abst - 2004)
When spliff gets in your eyes...
(news 2004)
http://www.guardian.co.uk/science/2004/jul/07/sciencenews.research
In-vitro corneal permeation of cannabinoids and their water-soluble phosphate ester prodrugs. (abst 2005) http://www.ncbi.nlm.nih.gov/pubmed/16105235 Marijuna Cured My Color-Blindness (anecdotal 2005)
http://mmj.tribe.net/thread/ae2e9a56-f117-4e96-b24d-ae799e956b00
Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration. (abst 2006)
Marijuana Compound May Help Stop Diabetic Retinopathy

(news - 2006)
Getting Eye On Cannabinoids
(news - 2006)
http://www.thehempire.com/index.php/cannabis/news/getting_eye_on_cannabinoids
Endocannabinoids in the retina: From marijuana to neuroprotection. (full - 2008)

655
Marijuana compound could prevent eye damage in diabetics
(news - 2006)
http://www.thehempire.com/index.php/cannabis/news/marijuana_compound_could_prevent_eye_damage_i n_diabetics
Neuroprotective effects of cannabidiol in endotoxin-induced uveitis: critical role of p38 MAPK activation. (full - 2008)
Topical WIN55212-2 alleviates intraocular hypertension in rats through a CB1 receptor mediated mechanism of action. (full 2008)
Mediation of Cannabidiol anti-inflammation in the Retina by Equilibrative Nucleoside Transporter and A2A Adenosine Receptor (full - 2008)
Reduction of Congenital Nystagmus in a Patient after Smoking Cannabis.
(abst - 2008)
http://www.unboundmedicine.com/medline/ebm/record/18306120/abstract/Reduction_of_Congenital_Nyst agmus_in_a_Patient_after_Smoking_Cannabis_
Assessing changes in pupillary size in Rifian smokers of kif (Cannabis sativa L.). (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18511011 The role of endocannabinoid system in physiological and pathological processes in the eye (abst - 2008)
http://www.unboundmedicine.com/medline/ebm/record/19195174/abstract/%5BThe_role_of_endocannabi noid_system_in_physiological_and_pathological_processes_in_the_eye%5D
Cannabidiol As a Putative Novel Therapy for Diabetic Retinopathy: A Postulated Mechanism of Action as an Entry Point for Biomarker-Guided Clinical Development. (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955420/?tool=pubmed Presence and regulation of cannabinoid receptors in human retinal pigment epithelial cells. (full 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697670/?tool=pubmed Cannabidiol protects retinal neurons by preserving glutamine synthetase activity in diabetes. (full - 2010)
Epidermal growth factor receptor transactivation by the cannabinoid receptor (CB1) and transient receptor potential vanilloid 1 (TRPV1) induces differential responses in corneal epithelial cells. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20619260 2-Arachidonoylglycerol (2-AG) Induces Corneal Epithelial Cell Migration via Cannabinoid CB1 Receptors (abst 2011)
656
Diabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation. (abst 2010)
Mutations in ABHD12 cause the neurodegenerative disease PHARC: An inborn error of endocannabinoid metabolism. (full 2011)
Modulation of Auditory and Visual Processing by Delta-9-Tetrahydrocannabinol and Cannabidiol: an fMRI Study. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21412224 Comparison Of Rat And Human Eyes For The Presence And Distribution Of Cb1 And Cb2 Receptors (abst - 2011)
Enhanced solubility, stability, and transcorneal permeability of delta-8tetrahydrocannabinol in the presence of cyclodextrins. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21637944 Endocannabinoid CB1 receptors modulate visual output from the thalamus. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21773721 Nonpsychotropic Cannabinoids, Abnormal Cannabidiol and Canabigerol-Dimethyl Heptyl, Act at Novel Cannabinoid Receptors to Reduce Intraocular Pressure. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21770780
WILSON'S DISEASE Cannabis sativa and dystonia secondary to Wilson's disease. (needs free registration) (abst - 2005) http://www.medscape.com/medline/abstract/15390041
WIN 55,212-2 - a synthetic cannabinoid, CB1 agonist Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells. (full - 1992) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC525583/ Cross-tolerance between delta-9-tetrahydrocannabinol and the cannabimimetic agents, CP 55,940, WIN 55,212-2 and anandamide. (full - 1993)
657
(+)-WIN 55,212-2, a novel cannabinoid receptor agonist, exerts antidystonic effects in mutant dystonic hamsters. (abst - 1994) http://www.ncbi.nlm.nih.gov/pubmed/7698178 Cannabinoid Receptor Agonists Protect Cultured Rat Hippocampal Neurons from Excitotoxicity (full - 1998) http://molpharm.aspetjournals.org/content/54/3/459.full Loss of Cannabinoid Receptor Binding and Messenger Rna Levels and Cannabinoid Agonist-stimulated [35s]guanylyl-5'o-(Thio)-triphosphate Binding in the Basal Ganglia of Aged Rats. (abst - 1998) http://www.ncbi.nlm.nih.gov/pubmed/9578396?dopt=Abstract Cannabinoids and Neuroprotection in Global and Focal Cerebral Ischemia and in Neuronal Cultures (full - 1999)
The role of cannabinoid receptors in intestinal motility, defaecation and diarrhoea in rats (abst - 1999) http://www.ncbi.nlm.nih.gov/pubmed/10611417 Involvement of Cannabinoid Receptors in the Intraocular Pressure-Lowering Effects of WIN55212-2 (full - 2000) http://jpet.aspetjournals.org/content/292/1/136.long Cannabinoids might reduce spasticity in multiple sclerosis
(full - 2000)
Effects of cannabinoid receptor agonists on neuronally-evoked contractions of urinary bladder tissues isolated from rat, mouse, pig, dog, monkey and human (full - 2000)
Central and peripheral cannabinoid modulation of gastrointestinal transit in physiological states or during the diarrhoea induced by croton oil (full - 2000)
Modulation of peristalsis by cannabinoid CB1 ligands in the isolated guinea-pig ileum (full - 2000) http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1571902&tool=pmcentrez Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. (full - 2000)
The synthetic cannabinoid WIN55,212-2 attenuates hyperalgesia and allodynia in a rat model of neuropathic pain (full - 2001)
658
The cannabinoid agonist WIN55,212-2 suppresses opioid-induced emesis in ferrets. (abst - 2001) http://www.ncbi.nlm.nih.gov/pubmed/11388542 The cannabinoid CB1 receptor antagonist SR 141716A reverses the antiemetic and motor depressant actions of WIN 55, 212-2 (abst 2001) http://pharmgkb.org/pmid/11698062 Increased Severity of Stroke in CB1 Cannabinoid Receptor Knock-Out Mice (full - 2002)
CB1 Receptors in the Preoptic Anterior Hypothalamus Regulate WIN 55212-2 [(4,5Dihydro-2-methyl-4(4-morpholinylmethyl)-1-(1-naphthalenyl-carbonyl)-6Hpyrrolo[3,2,1ij]quinolin-6-one]-Induced Hypothermia (full - 2002)
Contrasting effects of WIN 55212-2 on motility of the rat bladder and uterus. (full 2002) http://www.jneurosci.org/content/22/16/7147.long Influence of the CB1 receptor antagonist, AM 251, on the regional haemodynamic effects of WIN-55212-2 or HU 210 in conscious rats (full - 2002)
Effects of pharmacological manipulations of cannabinoid receptors on severity of dystonia in a genetic model of paroxysmal dyskinesia. (abst - 2002)
(full - 2003)
659
Effect of WIN 55212-2, a Cannabinoid Receptor Agonist, on Aqueous Humor Dynamics in Monkeys (full - 2003)
http://archopht.amaassn.org/cgi/content/full/121/1/87?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuana&sear chid=1&FIRSTINDEX=640&resourcetype=HWCIT
Immunoregulation of a viral model of multiple sclerosis using the synthetic cannabinoid R(+)WIN55,212 (full - 2003)
The cannabinoid agonist WIN 55, 212-2 increases nociception threshold in cholestatic rats: implications for the treatment of the pruritus of cholestasis. (abst 2003)
Cannabinoids: Defending the Epileptic Brain
(full - 2004)
The effect of WIN 55,212-2, a cannabinoid agonist, on tactile allodynia in diabetic rats. (abst 2004) http://www.ncbi.nlm.nih.gov/pubmed/15519750 Enhancing Cannabinoid Neurotransmission Augments the Extinction of Conditioned Fear (full - 2005) http://www.nature.com/npp/journal/v30/n3/full/1300655a.html Effects of cannabinoids on colonic muscle contractility and tension in guinea pigs. (full 2005) http://www.jstage.jst.go.jp/article/jnms/72/1/72_43/_article The cannabinoid receptor agonist WIN 55212-2 inhibits neurogenic inflammations in airway tissues. (full 2005) http://www.jstage.jst.go.jp/article/jphs/98/1/77/_pdf Systemic administration of WIN 55,212-2 increases norepinephrine release in the rat frontal cortex (abst - 2005) http://www.ncbi.nlm.nih.gov/pubmed/15927549 Cannabinoid Receptor-Mediated Apoptosis Induced by R(+)-Methanandamide and Win55,212-2 Is Associated with Ceramide Accumulation and p38 Activation in Mantle Cell Lymphoma (full - 2006) http://molpharm.aspetjournals.org/content/70/5/1612.full Increasing cannabinoid levels by pharmacological and genetic manipulation delay disease progression in SOD1 mice (full - 2006) http://www.fasebj.org/cgi/content/full/20/7/1003
660
Activation of G-proteins in brain by endogenous and exogenous cannabinoids. (full 2006) http://www.ncbi.nlm.nih.gov/pubmed/16584117 Effects of a Cannabinoid Agonist on Spinal Nociceptive Neurons in a Rodent Model of Neuropathic Pain (full - 2006) http://jn.physiology.org/cgi/content/full/96/6/2984 The Endocannabinoid System Controls Key Epileptogenic Circuits in the Hippocampus (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769341/?tool=pmcentrez Antinociceptive effect of cannabinoid agonist WIN 55,2122 in rats with a spinal cord injury (full - 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1861843/?tool=pmcentrez Activation of the Cannabinoid Type-1 Receptor Mediates the Anticonvulsant Properties of Cannabinoids in the Hippocampal Neuronal Culture Models of Acquired Epilepsy and Status Epilepticus (full - 2006)
Cannabinoid Receptor Agonist-induced Apoptosis of Human Prostate Cancer Cells LNCaP Proceeds through Sustained Activation of ERK1/2 Leading to G1 Cell Cycle Arrest (full - 2006) http://www.jbc.org/content/281/51/39480.full Modulation of paraoxon toxicity by the cannabinoid receptor agonist WIN 55,212-2. (abst 2006) http://www.ncbi.nlm.nih.gov/pubmed/16956707 Cannabinoid receptors as a target for therapy of ovarian cancer (abst - 2006)
http://www.aacrmeetingabstracts.org/cgi/content/abstract/2006/1/1084?maxtoshow=&hits=80&RESULTF ORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=560&resourcetype=HWCIT
Arthritis and cannabinoids: HU-210 and Win-55,212-2 prevent IL-1alpha-induced matrix degradation in bovine articular chondrocytes in-vitro. (abst - 2006)
The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells. (abst - 2006) http://www.ncbi.nlm.nih.gov/pubmed/16458258 Characterization of the neuroprotective effect of the cannabinoid agonist WIN-55212 in an in vitro model of hypoxic-ischemic brain damage in newborn rats. (abst 2006)
Role of cannabinoid receptor agonists in mechanisms of suppression of central pain syndrome. (abst - 2006)
Cannabinoids, in combination with (NSAIDS), produce a synergistic analgesic effect (news - 2006) http://www.norml.org/index.cfm?Group_ID=6819
661
Continuous infusion of the cannabinoid WIN 55,2122 to the site of a peripheral nerve injury reduces mechanical and cold hypersensitivity (full - 2007)
Antinociceptive effect of cannabinoid agonist WIN 55,2122 in rats with a spinal cord injury (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1861843/?tool=pmcentrez Activation of cannabinoid CB1 and CB2 receptors suppresses neuropathic nociception evoked by the chemotherapeutic agent vincristine in rats. (full 2007)
Subchronic cannabinoid agonist (WIN 55,212-2) treatment during cocaine abstinence alters subsequent cocaine seeking behavior. (full - 2007)
Cannabinoids elicit antidepressant-like behavior and activate serotonergic neurons through the medial prefrontal cortex. (full - 2007)
Antinociceptive Synergy Between the Cannabinoid Receptor Agonist WIN 55,212-2 and Bupivacaine in the Rat Formalin Test (full - 2007)
Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190006/?tool=pmcentrez Cross-sensitization and cross-tolerance between exogenous cannabinoid antinociception and endocannabinoid-mediated stress-induced analgesia (full - 2007)
CANNABINOID-INDUCED HYPERPHAGIA: CORRELATION WITH INHIBITION OF PROOPIOMELANOCORTIN NEURONS? (full - 2007)

Cannabinoid self-administration in rats: sex differences and the influence of ovarian function (full - 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190022/
662
Development of pharmacoresistance to benzodiazepines but not cannabinoids in the hippocampal neuronal culture model of status epilepticus (full - 2007)
Cannabinoid receptors agonist WIN-55,212-2 inhibits angiogenesis, metastasis and tumor growth of androgen-sensitive prostate cancer cell CWR22R{nu}1 xenograft in athymic nude mice (abst - 2007)
Synthetic form of THC is an effective anti-depressant at low doses (news - 2007)

http://www.news-medical.net/news/2007/10/24/31666.aspx?page=2
Cannabis: Potent Anti-Depressant In Low Doses, Worsens Depression At High Doses (news - 2007) http://www.sciencedaily.com/releases/2007/10/071023183937.htm Chronic cannabinoid administration in vivo compromises extinction of fear memory. (full - 2008) http://learnmem.cshlp.org/content/15/12/876.long Topical WIN55212-2 Alleviates Intraocular Hypertension in Rats Through a CB1 Receptor-Mediated Mechanism of Action (full - 2008)
Peripheral Cannabinoids Attenuate Carcinoma Induced Nociception in Mice (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771220/ Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats full - 2008)
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The influence of mast cell mediators on migration of SW756 cervical carcinoma cells. (full 2008) http://www.jstage.jst.go.jp/article/jphs/106/2/106_208/_article Differential effects of repeated low dose treatment with the cannabinoid agonist WIN 55,212-2 in experimental models of bone cancer pain and neuropathic pain. (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18611408 Cannabinoid 2 receptor induction by IL-12 and its potential as a therapeutic target for the treatment of anaplastic thyroid carcinoma. (abst - 2008)
Scientists are High on Idea that Cannabis Reduces Memory Impairment

(news - 2008)
Could Marijuana Substance Help Prevent Or Delay Memory Impairment In The Aging Brain? (news - 2008) http://www.sciencedaily.com/releases/2008/11/081119120141.htm WIN55,212-2, a Cannabinoid Receptor Agonist, Protects Against Nigrostriatal Cell Loss in the MPTP Mouse Model of Parkinsons Disease (full - 2009)
Sustained antinociceptive effect of cannabinoid receptor agonist WIN 55,212-2 over time in rat model of neuropathic spinal cord injury pain (full - 2009)
664
Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer (full - 2009) http://mct.aacrjournals.org/content/8/11/3117.full Cannabinoids inhibit fibrogenesis in diffuse systemic sclerosis fibroblasts (full - 2009)
http://rheumatology.oxfordjournals.org/content/48/9/1050.full
Cannabinoid agonist WIN-55,212-2 partially restores neurogenesis in the aged rat brain (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011092/?tool=pubmed New neuron production can be increased in the hippocampus of aged rats following cannabinoid treatment (abst 2009)
http://www.nature.com/mp/journal/v14/n12/full/mp2009122a.html
Cannabinoids attenuate the effects of aging upon neuroinflammation and neurogenesis. (abst 2009) http://www.ncbi.nlm.nih.gov/pubmed/19385063 Cannabinoid-mediated inhibition of recurrent excitatory circuitry in the dentate gyrus in a mouse model of temporal lobe epilepsy. (full 2010)
Cannabinoids excite circadian clock neurons.
(full 2010)
The synthetic cannabinoid WIN 55,212-2 sensitizes hepatocellular carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by activating p8/CCAAT/enhancer binding protein homologous protein (CHOP)/death receptor 5 (DR5) axis. (full 2010) http://molpharm.aspetjournals.org/content/77/5/854.long Sex difference in cell proliferation in developing rat amygdala mediated by endocannabinoids has implications for social behavior. (full 2010)
The effect of the activation of cannabinoid receptor on the proliferation and apoptosis of hepatoma HepG2 cells (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20368112 WIN55212-2 ameliorates atherosclerosis associated with suppression of proinflammatory responses in ApoE-knockout mice. (abst 2010)
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The cannabinoid WIN55212-2 promotes neural repair after neonatal hypoxia-ischemia. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/21115947 The cannabinoid WIN55, 212-2 abrogates dermal fibrosis in scleroderma bleomycin model. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/21177293 Pharmacologically induced hypothermia with cannabinoid receptor agonist WIN55, 2122 after cardiopulmonary resuscitation (abst 2010)
Cannabinoid self-administration attenuates PCP-induced schizophrenia-like symptoms in adult rats. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/19854030 Antiproliferative effects of cannabinoid agonists on deep infiltrating endometriosis. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/21057002 Effect of a synthetic cannabinoid agonist on the proliferation and invasion of gastric cancer cells. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20336665 Cannabinoid Receptor Agonist WIN-55,212-2 Protects Differentiated PC12 Cells From Organophosphorus- Induced Apoptosis (abst 2010)
http://ijt.sagepub.com/content/29/2/201.abstract
Chronic Low Doses of a Cannabinoid Causes New Brain Cell Formation

http://cannabination.com/tag/nih/
(news - 2010)
WIN55,212-2 induces cytoplasmic vacuolation in apoptosis-resistant MCL cells. (full 2011) http://www.nature.com/cddis/journal/v2/n11/full/cddis2011106a.html
666
Regulatory effect of cannabinoid receptor agonist on chemokine-induced lymphocyte chemotaxis. (full 2011) http://www.jstage.jst.go.jp/article/bpb/34/7/1090/_pdf Cannabinoids prevent the development of behavioral and endocrine alterations in a rat model of intense stress. (full 2011)
Protective effects of CB1 receptor agonist WIN 55.212-2 in seizure activity in the model of temporal lobe epilepsy (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21469332/abstract/%5BProtective_effects_of_CB1 _receptor_agonist_WIN_55_212_2_in_seizure_activity_in_the_model_of_temporal_lobe_epilepsy%5D_
Synthetic cannabinoid WIN 55,212-2 mesylate enhances the protective action of four classical antiepileptic drugs against maximal electroshock-induced seizures in mice. (abst 2011)
http://www.unboundmedicine.com/medline/ebm/record/21238473/abstract/Synthetic_cannabinoid_WIN_5 5212_2_mesylate_enhances_the_protective_action_of_four_classical_antiepileptic_drugs_against_maxima l_electroshock_induced_seizures_in_mice_
The Cannabinoid WIN 55212-2 Mitigates Apoptosis and Mitochondrial Dysfunction After Hypoxia Ischemia. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21909954 Cannabinoid applications in glaucoma. (abst 2011)
Identification of the synthetic cannabinoid R(+)WIN55,212-2 as a novel regulator of IFN regulatory factor 3 (IRF3) activation and IFN-{beta} expression: relevance to therapeutic effects in models of multiple sclerosis. (abst 2011)
667
The antimitogenic effect of the cannabinoid receptor agonist WIN55212-2 on human melanoma cells is mediated by the membrane lipid raft. (abst 2011)
Antiproliferative mechanism of a cannabinoid agonist by cell cycle arrest in human gastric cancer cells. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21312237 Effects of Cannabinoid Agonists on Sheep Sphincter of Oddi in vitro. (abst 2011)
Cannabinoids Prevent the Development of Behavioral and Endocrine Alterations in a Rat Model of Intense Stress. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/21918506 Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent. (abst 2011) http://www.ncbi.nlm.nih.gov/pubmed/22110202 (9)-THC and WIN55,212-2 affect brain tissue levels of excitatory amino acids in a phenotype-, compound-, dose-, and region-specific manner (abst 2011)
Inverse relationship of cannabimimetic (R+)WIN 55, 212 on behavior and seizure threshold during the juvenile period. (abst 2012)
The Cannabinoid WIN 55212-2 Mitigates Apoptosis and Mitochondrial Dysfunction After Hypoxia Ischemia. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/21909954 Tolerance to cannabinoid-induced behaviors in mice treated chronically with ethanol. (abst 2012) http://www.ncbi.nlm.nih.gov/pubmed/21701813
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WITHDRAWAL SYNDROME An Abstinence Syndrome Following Chronic Administration of Delta-9terahydrocannabinol in Rhesus Monkeys. (abst 1980)
Marijuana withdrawal syndrome in a woman. (abst 1984)


http://www.ukcia.org/research/merck.htm
(excerpt- 1987)
Marijuana abstinence effects in marijuana smokers maintained in their home environment. (full 2001)
http://archpsyc.ama-assn.org/cgi/content/full/58/10/917
Delta9-tetrahydrocannabinol releases and facilitates the effects of endogenous enkephalins: reduction in morphine withdrawal syndrome without change in rewarding effect. (abst 2001) http://www.ncbi.nlm.nih.gov/pubmed/11359533 The Time Course and Significance of Cannabis Withdrawal. (abst 2003)
http://medical-journals.healia.com/doc/12943018/The-time-course-and-significance-of-cannabiswithdrawal
Decrease in prostaglandin level is a prerequisite for the expression of cannabinoid withdrawal: a quasi abstinence approach. (abst 2005)
A Within-Subject Comparison of Withdrawal Symptoms During Abstinence From Cannabis, Tobacco, and Both Substances (full - 2008)
Cannabis withdrawal in the United States: results from NESARC.

(full - 2008)
(excerpt - 2008)
The FAAH inhibitor URB-597 ameliorates cannabinoid withdrawal in mice (abst - 2008)
Pot, Tobacco Withdrawal Equally Rough
(news - 2008)
http://www.webmd.com/mental-health/news/20080130/pot-tobacco-withdrawal-equally-rough
Withdrawal Phenomena and Dependence Syndrome After the Consumption of "Spice Gold" (full - 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719097/?tool=pmcentrez
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Actions of delta-9-tetrahydrocannabinol in cannabis
(full - 2009)
Cannabis withdrawal severity and short-term course among cannabis-dependent adolescent and young adult inpatients (abst - 2009)
http://www.unboundmedicine.com/medline/ebm/record/19783382/abstract/Cannabis_withdrawal_severity_ and_short_term_course_among_cannabis_dependent_adolescent_and_young_adult_inpatients_
Anxiety-like effects of SR141716-precipitated delta9-tetrahydrocannabinol withdrawal in mice in the elevated plus-maze. (abst 2010)
http://www.unboundmedicine.com/medline/ebm/record/20363293/abstract/Anxiety_like_effects_of_SR141 716_precipitated_delta9_tetrahydrocannabinol_withdrawal_in_mice_in_the_elevated_plus_maze_
Antagonist-elicited cannabis withdrawal in humans.

(abst 2011)
WOUNDS/ INJURIES Differential Expression of Cannabinoid Receptors in the Human Colon: Cannabinoids Promote Epithelial Wound Healing (abst - 2005)
http://www.gastrojournal.org/article/PIIS0016508505009297/abstract
A multicenter dose-escalation study of the analgesic and adverse effects of an oral cannabis extract (Cannador) for postoperative pain management. (full - 2006)
Cannador: Drug from cannabis plant-extract to reduce surgery pain New frontier for medical cannabis -- topical pot
http://www.canaseed.com/CannabisNews.aspx?id=138
(news - 2006)
(news - 2007)
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Evidence for a Role of Endocannabinoids, Astrocytes and p38 Phosphorylation in the Resolution of Postoperative Pain (full - 2010)
The cannabinoid receptor type 2 is time-dependently expressed during skeletal muscle wound healing in rats (abst - 2010) http://www.ncbi.nlm.nih.gov/sites/pubmed Endocannabinoid-like N-arachidonoyl serine is a novel pro-angiogenic mediator. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20649563 Epidermal growth factor receptor transactivation by the cannabinoid receptor (CB1) and transient receptor potential vanilloid 1 (TRPV1) induces differential responses in corneal epithelial cells. (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20619260 Involvement of the endocannabinoid system in periodontal healing. (abst - 2010)
Expression of cannabinoid receptor I during mice skin incised wound healing course (abst 2010) http://www.ncbi.nlm.nih.gov/pubmed/20967946 Compound boosts marijuana-like chemical in the body to relieve pain at injury site (news - 2010) http://www.eurekalert.org/pub_releases/2010-09/uoc--cbm092010.php Study: Smoking pot may ease chronic pain (news - 2010)
2-Arachidonoylglycerol (2-AG) Induces Corneal Epithelial Cell Migration via Cannabinoid CB1 Receptors (abst 2011)
YOUNG ADULTS - see CHILDREN/ YOUNG ADULTS
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A few definitions to help you alongAgonist a chemical that activates a receptor Analogue a synthetic version Anandamide - A messenger chemical made by your body similar to THC Angiogenesis - making new blood vessels, often to feed a tumor Antagonist a chemical that blocks the action of an agonist Anti-nociception- pain relieving Anxiolytic calming, anti-anxiety Apoptosis - a process that leads to the normally programed death of a cell. Autophagy the cell self-destructs Beta amyloid plaque / -amyloid/ A the stuff that gums up your brain in Alzheimers Bronchodilator opens up the lungs Cannabinoids they activate CB receptors and come from your body, cannabis or labs. Chronic long term Downregulation a decrease in number Endocannabinoid a chemical messenger made by your body- anandamide and 2-AG Endocannabinoid System a system of chemical receptors on and between your cells Endogenous made in your own body Epidermal pertaining to the skin Hyperalgesia severe pain In vivo in a live animal In vitro in a test tube Ischemia damage from lack of blood to an area Ligand - a chemical that binds to a receptor. THC is a ligand of CB1 and CB2 receptors Metastasis spreading through the body Neurogenesis new brain cells are being formed Neuropathic Pain pain due to nerve injury Neuroprotective protects nerves and brain cells Nonpsychoactive wont get you high Phytocannabinoid a cannabinoid produced by a plant THC and CBD are examples Receptors - These receive the chemical messages and send them into our cells. Upregulation increase in number Vasodilator expands the blood vessels
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THE INDEX - January 2012

Introduction............................................................................................. ........................................1 ACEA/ ARACHIDONYL-2'-CHLOROETHYLAMIDE.. 2 ACHILLES TENDINOSIS.4 ACNE...4 ADD/ ADHD...................................................................................................................................4 ADDICTION...........................................................................................................................6 2-AG /2-ARACHIDONOYLGLYCEROL.8 2-AGE/ 2-ARACHIDONYL GLYCERYL ETHER/ NOLADIN ETHER...17 AGING/ USE BY SENIORS ........................................................................................................18 AIDS see HIV AJULEMIC ACID.........................................................................................................................21 ALCOHOLISM.............................................................................................................................22 ALLERGIES AND CANNABIS.................................................................................. ........26 ALLERGIES TO CANNABIS..27 ALS / AMYOTROPHIC LATERAL SCLEROSIS......................................................................28 ALZHEIMER'S DISEASE............................................................................................................30 AM- 251.........................................................................................................................................36 AM-281..40 AM-404..........................................................................................................................................41 AM-630..........................................................................................................................................42 AM-694..43 AM-1241........................................................................................................................................43 AM-1346........................................................................................................................................44 AM-171045 AM-2233....45 AM- 4054.......................................................................................................................................45 AM- 4113.......................................................................................................................................46 AM 6545....46 AMOTIVATIONAL SYNDROME..............................................................................................46 ANANDAMIDE............................................................................................................................47 ANECDOTAL / PERSONAL STORIES......................................................................................65 ANOREXIA NERVOSA - also see APPETITE STIMULANT.............................................................66 ANTI-BACTERIAL PROPERTIES.............................................................................................68 ANTI-FUNGAL PROPERTIES....................................................................................................69 ANTI-INFLAMMATORY PROPERTIES............................................................................. .69 ANTIMICROBIAL PROPERTIES...76 ANTIOXIDANT PROPERTIES...................................................................................................77 ANXIOLYTIC EFFECTS.............................................................................................................78 APPETITE STIMULANT.............................................................................................................82 ARACHIDONYL-2'-CHLOROETHYLAMIDE- see ACEA 2-ARACHIDONOYLGLYCEROL- see 2-AG ARTHRITIS...................................................................................................................................90 AS- 1535907..93 AS-1907417...94
673
ASTHMA.......................................................................................................................................94 ATHEROSCLEROSIS..................................................................................................................95 AUTISM........................................................................................................................................97
BACK PAIN..................................................................................................................................99 BETA-CARYOPHYLENE/ (E)-BCP...........................................................................................99 BIPOLAR DISORDER...............................................................................................................100 BLADDER/ URINARY FUNCTIONS.......................................................................................100 BLEPHAROSPASM...................................................................................................................100 BLOOD........................................................................................................................................100 BLOOD PRESSURE...................................................................................................................103 BONES- see OSTEOPOROSIS BONE MARROW.. 106 BOWEL DISORDERS - also see GERD, COLITIS.........................................................................106 BRAIN CELLS- see NEURONS BRAIN- PHYSICAL EFFECTS.................................................................................................115 BRAIN TRAUMA.......................................................................................................................117 BREASTFEEDING/ INFANT APPETITE.................................................................................119 BULIMIA.120
CANCER BASAL CELL CARCINOMA - see CANCER SKIN CANCER BLADDER / URETHRAL..121 CANCER- BONE........................................................................................................................121 CANCER- BREAST....................................................................................................................122 CANCER- CERVICAL...............................................................................................................125 CANCER- CHEMOTHERAPY- see CHEMOTHERAPY CANCER- CHOLANGIOCARCINOMA...................................................................................126 CANCER- COLON /COLORECTAL.........................................................................................127 CANCER ENDOMETRIAL....129 CANCER- GASTRIC..................................................................................................................129 CANCER- GLIOMA..................................................................................................................130 CANCER- HEAD AND NECK..................................................................................................135 CANCER- KAPOSI'S SARCOMA............................................................................................135 CANCER KIDNEY.136 CANCER- LEUKEMIA.............................................................................................................136 CANCER LIVER.137 CANCER- LUNG.......................................................................................................................138 CANCER- LYMPHOMA...........................................................................................................141 CANCER- MELANOMA...........................................................................................................142 CANCER - NEUROBLASTOMA..............................................................................................143 CANCER- ORAL........................................................................................................................144 CANCER- OVARIAN.................................................................................................................145
674
CANCER- PANCREATIC..........................................................................................................145 CANCER- PITUITARY ADENOMA........................................................................................146 CANCER PNET / PRIMITIVE NEUROECTODERMAL TUMOR..146 CANCER- PROSTATE...............................................................................................................146 CANCER - RHABDOMYOSARCOMA....................................................................................148 CANCER- RISK CANNABIS VS TOBACCO..........................................................................149 CANCER- SKIN..........................................................................................................................149 CANCER - SQUAMOUS CELL CARCINOMA...150 CANCER- TESTICULAR...........................................................................................................151 CANCER - THYMOMA.............................................................................................................151 CANCER- THYROID.................................................................................................................151 CANCER- VARIOUS/ UNNAMED...........................................................................................152 CANNABICHROMENE.............................................................................................................159 CANNABIDIOL/ CBD...............................................................................................................160 CANNABIDIOLIC ACID...182 CANNABIGEROL / CBG...........................................................................................................182 CANNABINOID HYPEREMESIS SYNDROME.184 CANNABINOID RECEPTORS - see ENDOCANNABINOID SYSTEM, CBRs CANNABINOR...186 CANNADOR...............................................................................................................................186 CARDIOVASCULAR- see HEART DISEASE CARPAL TUNNEL SYNDROME.187 CBR- CB 1 RECEPTORS-..........................................................................................................187 CBR CB 2 RECEPTORS.........................................................................................205 CBR GPR 40 RECEPTORS..........218 CBR GPR 55/ CB 3 RECEPTORS...........................................................................................219 CBR - GPR109 RECEPTORS.....................................................................................................221 CBR GPR 119 RECEPTORS...................................................................................................222 CELIAC DISEASE..222 CEREBRAL PALSY...223 CESAMET- see NABILONE CHEMICAL COMPOSITION....................................................................................................223 CHEMOTHERAPY.....................................................................................................................231 CHILDREN/ YOUNG ADULTS................................................................................................236 CHOLERA...243 CHOLESTEROL.244 CHRONIC FATIGUE SYNDRONE...244 COGNATIVE EFFECTS- see IQ COLITUS.244 COPD/ LUNG FUNCTION........................................................................................................246 COUGH.......................................................................................................................................247 COWPOX248 CP- 47,497...................................................................................................................................248 CP 50,556-1 / LEVONANTRADOL..250 CP- 55,940...................................................................................................................................251 CROHN'S - see BOWEL DISORDERS
675
CRUETZFELDT-JACOB DISEASE- see MAD COW DISEASE CT-3 also see AJULMIC ACID.......................................................................................................254 CYSTIC FIBROSIS.....................................................................................................................254 CYSTITIS....................................................................................................................................255
DENTISTRY - see TEETH DEPRESSION.............................................................................................................................255 DERMATITIS.............................................................................................................................259 DEXANABINOL - see HU-211 DIABETES..................................................................................................................................261 DOWNS SYNDROME..267 DRIVING AND CANNABIS......................................................................................................267 DRONABINOL...........................................................................................................................270 DRUG INTERACTIONS- see INTERACTIONS WITH OTHER DRUGS DRUG TESTING........................................................................................................................274 DRUG TESTING - BLOOD.......................................................................................................277 DRUG TESTING BREATH TEST..279 DRUG TESTING - HAIR...........................................................................................................279 DRUG TESTING- OTHER.........................................................................................................281 DRUG TESTING - ORAL..........................................................................................................282 DRUG TESTING - URINE.........................................................................................................283 DYSKINESIA..288 DYSTONIA.................................................................................................................................289
ECZEMA....................................................................................................................................290 EDEMA........................................................................................................................... ..291 EHLERS-DANLOS SYNDROME............................................................................................291 ELMIRIC ACIDS.......................................................................................................................291 ENCEPHALITUS.......................................................................................................................292 ENCEPHALOMYELITIS/ EAE................................................................................................292 ENDOCANNABINOIDS...........................................................................................................293 ENDOCANNABINOID SYSTEM also see CBRs..................................................................301 ENDOMETRIOSIS....................................................................................................................319 EPILEPSY...................................................................................................................................319
FAMILIAL MEDITERRANEAN FEVER................................................................................325 FERTILITY................................................................................................................................325 FEVER/ TEMPERATURE CONTROL.....................................................................................327 FIBROMYALGIA......................................................................................................................329 FLU / INFLUENZA....................................................................................................................331
676
GATEWAY THEORY................................................................................................................331 GENDER-BASED DIFFERENCES...........................................................................................333 GERD/GASTRO-ESOPHAGEAL REFLUX DISEASE............................................................336 GLAUCOMA..............................................................................................................................336 GOUT..341 GRANULOMA341 GRAVE'S DISEASE...................................................................................................................341 GWP- 42006....342 GYNOCOLOGY AND OBSTETRICS......................................................................................342
HAIR............................................................................................................................................343 HEADACHE- see MIGRAINE HEARING also see TINNITUS........................................................................................................344 HEART DISEASE/ CARDIOVASCULAR...............................................................................344 HEMORRHAGIC SHOCK.....353 HEPATITIS.................................................................................................................................353 HEREDITARY MULTIPLE EXTOSES.355 HERPES VIRUS..........................................................................................................................355 HEXAHYDROCANNABINOLS................................................................................................356 HICCUPS.....................................................................................................................................356 HISTORICAL STUDIES -PRE 1937..........................................................................................357 HISTORY- ANCIENT USE........................................................................................................360 HISTORY-1937 TO PRESENT..................................................................................................361 HIV / AIDS..................................................................................................................................365 HORMONES...............................................................................................................................369 HPV/ HUMAN PAPILLOMA VIRUS.......................................................................................373 HU-210........................................................................................................................................373 HU-211........................................................................................................................................377 HU-308........................................................................................................................................378 HU-310379 HU-320........................................................................................................................................379 HU-331........................................................................................................................................379 HU-910380 HUNTINGTON'S DISEASE......................................................................................................380 HYPEREMESIS - see CANNABINOID HYPEREMESIS SYNDROME HYSTERECTOMY.....................................................................................................................383
IBS - see BOWEL DISORDERS IDIOPATHIC INTRACRANIAL HYPERTENSION................................................................384 IDRASIL..384
677
IMMUNE SYSTEM....................................................................................................................384 INCONTINENCE - see BLADDER OVERACTIVITY INDICATIONS AND CLINICAL USES....................................................................................387 INFLUENZA-see FLU INJURIES - see WOUNDS/ INJURIES INTERACTIONS WITH OTHER DRUGS................................................................................388 31 - IP 751 see AJULEMIC ACID ISSACS SYNDROME/ ACQUIRED NEUROMYOTONIA397 IQ/ MEMORY/ COGNATIVE EFFECTS..................................................................................397
JWH-015......................................................................................................................................403 JWH-018......................................................................................................................................405 JWH-073......................................................................................................................................408 JWH-100 / AM -678409 JWH-133......................................................................................................................................409
KIDNEYS....................................................................................................................................412 KNOCK-OUT MICE 413 LEGIONAIRES DISEASE..415 LEISHMANIASIS.......................................................................................................................416 LIVER - NON HEPATITIS.........................................................................................................416 LONG TERM USE EFFECTS....................................................................................................421 LUNG FUNCTION.....................................................................................................................423 LUPUS.........................................................................................................................................424 LYME DISEASE.425
MACULAR DEGENERATION.....425 MAD COW/ CRUETZFELDT-JACOB DISEASE....................................................................425 MARINOL..................................................................................................................................426 MDA 19...427 MEIGE'S SYNDROME..............................................................................................................428 MEMORY- see IQ MENIERE'S SYNDROME.........................................................................................................428 MENINGITIS..............................................................................................................................428 MENOPAUSE.............................................................................................................................428 MENTAL DISORDERS - see SCHIZOPHRENIA METHODS OF USE BREATH STRIPS429 METHODS OF USE- CAPSULES........................................................................ ....................430 METHODS OF USE DECARBOXYLATION...430
678
METHODS OF USE- E-CIGARETTES..430 METHODS OF USE- EDIBLES...............................................................................................431 METHODS OF USE- EDIBLES - BEVERAGES....................................................................432 METHODS OF USE- EDIBLES - FOODS.............................................................................433 METHODS OF USE - INHALERS..434 METHODS OF USE - INJECTION............................................................................................435 METHODS OF USE - NASAL SPRAYS...................................................................................436 METHODS OF USE RSO / RICK SIMPSONS OIL.....436 METHODS OF USE - SMOKING.............................................................................................437 METHODS OF USE - SUPPOSITORIES..................................................................................441 METHODS OF USE - TINCTURES..........................................................................................441 METHODS OF USE - TOPICAL OINTMENTS.......................................................................442 METHODS OF USE -TRANSDERMAL PATCH.....................................................................444 METHODS OF USE - VAPORIZERS.......................................................................................444 METHODS OF USE- VARIOUS...............................................................................................446 MIGRAINE/ HEADACHE.........................................................................................................447 MISCELANEOUS STUFF..........................................................................................................448 MORNING SICKNESS..............................................................................................................454 MORTALITY RATES................................................................................................................455 MOTION SICKNESS..................................................................................................................456 MRSA/ METHICILLIN-RESISTANT STAPHLOCOCCUS AUREUS...................................457 MULTIPLE SCLEROSIS/ MS....................................................................................................458 MUSCULAR DYSTROPHY/ MD..............................................................................................469 MUSCLE RELAXANT...............................................................................................................469
NABILONE.................................................................................................................................470 NAIL-PATELLA SYNDROME.....475 NAUSEA.....................................................................................................................................475 NEURONS/ BRAIN CELLS.......................................................................................................481 NEUROPATHIC PAIN...............................................................................................................487 NEUROPROTECTANT..............................................................................................................492 NIEMANN-PICK DISEASE.......................................................................................................497 NIGHT SWEATS....498 NUTRITION - GENERAL..........................................................................................................498 NUTRITION - HEMP SEED......................................................................................................499 NUTRITION - HEMP SEED OIL...............................................................................................502
O-1602.504 O-1966.504 OBESITY.....................................................................................................................................505 OBSESSIVE COMPULSIVE DISORDER.................................................................................510 OMEGA-3/ CB1 CONNECTION ......511
679
ORGAN TRANSPLANTS.........................................................................................................512 OSTEOPOROSIS/ BONES........................................................................................................514 OVERDOSES.............................................................................................................................517 OVERVIEWS.............................................................................................................................517
PAIN............................................................................................................................................519 PANCREATITIS.........................................................................................................................527 PERINATAL HYPOXIC-ISCHEMIC INJURY.528 PARKINSON'S DISEASE..........................................................................................................529 PATENTS RELATED TO CANNABIS.....................................................................................532 PEA PALMITOYLETHANOLAMIDE...537 PHARC538 PHYTOCANNABINOIDS / PLANT EXTRACTS....................................................................539 POISONING ORGANOPHOSPHATE....544 POISONING PARAQUAT..544 POST-OPERATIVE PAIN..........................................................................................................545 POST TRAUMATIC STRESS DISORDER/ PTSD...................................................................546 PRADER WILLI SYNDROME..549 PREGNANCY/ PRENATAL EXPOSURE................................................................................550 PRIONS.......................................................................................................................................555 PROXIMAL MYOTONIC MYOPATHY / PROMM................................................................556 PRURITIS (chronic itch).............................................................................................................556 PSORIASIS.................................................................................................................................558
QUITTING CANNABIS.559 QUITTING OTHER DRUGS......................................................................................................560
RADIATION-INDUCED NAUSEA...........................................................................................563 RADIATION SICKNESS...564 REFLEX SYMPATHETIC DYSTROPHY564 RESTLESS LEG SYNDROME..................................................................................................564 RETINITIS PIGMENTOSA565 RIMONABANT..........................................................................................................................565 R(+)-METHANANANDAMIDE....................................................................................569 RWJ- 400065.............................................................................................................................. 571
SAFETY AS A MEDICINE........................................................................................................571 SAFETY-ADULTERANTS/ CONTAMINANTS......................................................................573
680
SATIVEX....................................................................................................................................575 SCHIZOPHRENIA/ MENTAL DISORDERS...........................................................................578 SCLERODERMA.......................................................................................................................585 SEPTIC SHOCK.........................................................................................................................586 SICKLE CELL DISEASE...........................................................................................................587 SINUSITIS....................................................................................................................... ...587 SLEEPING SICKNESS/ TRYPANOSOMIASIS...588 SLEEP MODULATION..............................................................................................................588 SMALLPOX....590 SMELL / ODOR DETECTION...590 SMOKED CANNABIS AS A MEDICATION...........................................................................591 SOCIAL ADJUSTMENT/ BEHAVIOR.....................................................................................595 SPASTICITY................................................................................................................... ...597 SPICE...601 SPINAL CORD INJURY............................................................................................................603 SPLEEN...606 STEM CELLS..606 STRESS...607 STORAGE...608 STROKE......................................................................................................................................608
TAK SERIES..612 TASTE.612 TAXONOMY/ GENETICS OF CANNABIS.............................................................................613 TEA AS MEDICINE...................................................................................................................617 TEETH /DENTISTRY.................................................................................................................617 THC/ TETRAHYDROCANNABINOL......................................................................................618 THC ACID/ THCA......................................................................................................................636 TETRAHYDROCANNABINOL-HEMISUCCINATE / THC-HS............................................637 TETRAHYDROCANNABOVARIN/ THCV.............................................................................638 TIME PERCEPTION...640 TINNITUS- also see HEARING......................................................................................................640 TOBACCO VS CANNABIS.......................................................................................................641 TOLERANCE..............................................................................................................................645 TOURETTE'S SYNDROME......................................................................................................646 TRICHOTILLOMANIA..648 TUBERCULOSIS........................................................................................................................648
ULCERATIVE COLITIS- see COLITIS, also BOWEL DISORDERS URB - 597/ KDS-4103...............................................................................................................649 URB - 754...................................................................................................................................651 URB - 973...................................................................................................................................651
681
VAPORIZERS - see METHODS OF USE- VAPORIZERS VETERINARY USE/ ANIMALS...............................................................................................652 VISION........................................................................................................................................654
WILSON'S DISEASE.............................................................................................................657 WIN 55,212-2..............................................................................................................................657 WITHDRAWAL SYNDROME..................................................................................................669 WOUNDS/ INJURIES.................................................................................................................670
YOUNG ADULTS - see CHILDREN/YOUNG ADULTS
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Introduction - July 2011- This years message to all of you is a little different. I am going to be explaining a major scientific discovery- the Omega-3 / CB1 connection, and how it affects your healing with cannabis! But to understand fully this discovery, we need to revisit Biology 101. Every cell in your body has tiny chemical receptors all over the cells skin or cell membrane. These receptors work kind of like an ignition switch- you put the right type of chemical key into a receptor and it turns on some kind of action. The type 1 cannabinoid receptors (CB1s) are the ones we are interested in looking at. They are found both in the body and the brain. Turning on a CB1 receptor with either an endocannabinoid that your body makes, or a phytocannabinoid like THC, can result in many different things occurring. A cancer cell may be told to die through a process called apoptosis, it may activate a basic instinct such as nursing, soothe an irritated digestive tract, or simply ease your pain. The CB1 receptors in your brain are the ones to blame, or praise, for the cannabis high. Every time a cell divides, whether it is a brain cell, or a body cell, it needs to make new skin to grow back to its full size, and that involves making a whole bunch of new receptors. And this is where the cutting-edge science starts-- to make functional CB1 receptors, you absolutely need Omega-3! In Nutritional omega-3 deficiency abolishes endocannabinoidmediated neuronal functions, the Omega-6-rich western diet is implicated in our declining mental and physical health. The ideal proportion of Omega-6 to Omega-3 is around 3 to 4 parts Omega-6 to every 1 part Omega-3. Our western diet can deliver up to a 50 to 1 ratio! When no Omega-3 is available, our bodies will jury-rig a new receptor with an Omega-6 where there should be an Omega-3. This results in a small, but important chunk, the Gi/o effector protein, not getting attached. As with a machine, the pieces need to be assembled right to work! A drop in the number of working CB1 receptors is an early clinical sign in Parkinsons, colon cancer, Huntingtons, and heralds a high risk for premature birth. Mice bred to be low in CB1 receptors have more severe heart attacks and strokes. Cancers ravage them. They age and become senile earlier than normal mice. They are used to study neurological conditions and bowel disorders. They often seem depressed. They sound a lot like many modern Americans. The three most common sources of Omega-3 are fish oil, flax seed oil and hemp seed oil. Cannabis is an effective and safe herbal medicine, but we need functioning CB1 receptors for it to work its miracles. Virtually every person needs more Omega-3 in their diet, but none as much as the medical users of cannabis! Cannabis heals us using our cannabinoid receptors, and also provides the Omega-3 that we need to make healthy CB receptors, so we can heal. And that is the simple, but scientific truth. If the truth wont do, then something is wrong!
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Introduction - July 2010 - This is my third year of sharing "Granny's list" with all of you. Last year, I told you "How this list came about." This year, it's "Why you should be sharing my list!" From 60 pages, a symbolic celebration of my then 60 years on Earth, my list has grown to an equally symbolic 420 pages of links, in hopeful anticipation of the dawning of medical freedom in other states. My "Granny's list" contains 100s of studies about cannabis and how can heal- all done in an environment of "strong discouragement" on the part of the US government. How large my collection would be if research into this healing herb had been unrestricted? What would we know if we could have researched during those 70- odd years of prohibition? As a medicine, cannabis is potentially invaluable- this collection is ample proof of that! From stopping hiccups, to halting breast cancer's terrible spread, cannabis works! But there are still too many "may"s and "might"s when it comes to cannabis. We need more research, which will not, and cannot, happen until cannabis is legalized and rescheduled. When I began using cannabis medically over 40 years ago, there was no such thing as "medical use"- not even the concept existed! Education has made the difference. Somewhere along the line, every one of the people who have voted to legalize medical use in their state, learned that cannabis was an effective medicine, perhaps from a relative's use, or from a program they saw, or a study they read. They learned the truth. In a Canadian survey of doctors, a majority admitted that most of what they knew about cannabis came from their patients! They had learned only the "government line" in medical school. That was in Canada, where medical use is federally legal! So how much does your doctor really know about cannabis? My list gives you a way to educate him. And you shouldn't stop with your doctor. Local city councilmen and commissioners have the power to ban dispensaries through local ordinances. It is easier to educate them before it's an issue. They need the medical facts about cannabis to make logical decisions! We all know someone who has diabetes, fibro, cancer or MS. They shouldn't have to suffer, physically, financially, or legally, for using a safer-than-aspirin herbal medicine. One they could easily grow if sane cannabis laws were in place. Home-grown cannabis is cheaper and works faster than any pill and the side effects are far more pleasant. Cannabis, with its remarkable safety record, should be the first medicine tried, not be the medicine of last resort! It is only by educating others, that we can bring cannabis back into mainstream medicine where it belongs. Please share the facts about cannabis with those around you, and back them up with medical studies from my list. The simple truth is "Cannabis heals". And as my wise old grandfather once said, "If the truth won't do, then something is wrong!"
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Intro - 2008 "If the truth won't do, then something is wrong!" Those were the furious words of my grandfather to my Mother. I had walked in from joyfully stuffing my face with red raspberries in the garden, straight into "war zone"! My gentle grandfather in a fury, his hand raised! Mom was just beginning to shrink back away from him. They saw me and quickly sent me away. But it was too late, the scene and the words were seared into my 5-year-old brain. That was over 55 years ago, but I still remember it clearly. My grandfather was a minister, one very short step away from God in my 5 year old mind. It was one of those life changing moments. It is still rare for me to tell a lie. I never found out what my Mother's lie was. As I child, I suffered a traumatic head injury. Another child tried to murder me with a hammer. I was left with frequent migraines. At 19, like many rebellious teens, I tried cannabis. It took about a year for me to make the connection between using cannabis and the absence of my normally frequent migraines. I have used cannabis ever since. I am an avid reader. While perusing an old book on herbal medicine, I read how the little old ladies of Mexico made and used a cannabis/tequila rub on their arthritic hands. Then I met Joey, an epileptic musician. He told me another interesting fact- when he had pot he could cut his medication in half! On a camping trip years later, I smelled an unmistakable odor. Following my nose, I was totally shocked to find a grandmotherly lady in her 70s puffing away on a delicate oriental pipe. "Parkinson's. And the pot's way cheaper than the pills!" Her nephew kept her well supplied, she said. We had a nice chat about various medical uses of cannabis. Epilepsy, Parkinson's, arthritis, and my migraines! What else was it good for? Yet every news article on cannabis that I saw, claimed one new horror after another. Men grew breasts and were impotent. Women became sterile or miscarried. It made you crazy and murderous. Made you lazy and do nothing. It caused cancer and heart attacks...What I had learned on my own and from others and what I was being told in the press were so different! What was the truth? I began researching. I printed the first studies up and kept them in a notebook, just as a personal reference. The notebook quickly filled. I started a Word file of the URLs and on July 30 2007, I posted it. It continues to grow.
Here's some of what I have found. All I've done is copy the URLs, then put them all in some semblance order for everyone to use as a reference. Please feel free to share this list with anyone who could benefit from it.
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July 30, 2007 Its my 60th birthday! Thats a pretty big milestone. Ive out-lived my beautiful, crazy mother (59 years 11 months) and Ive been married and toking for 40 years. So, since 60 rolls around only once, I decided to give you a gift! I though Id share my notebook with you. It is a compilation of medical studies, news articles and information on cannabis. In addition to the obvious use of people who are ill getting information on what might heal them, I hope that many of you will take up a challenge from me. I want this spread around- to your doctor, your politicians, ministers, and anyone who could use the info. Information does no good if it is hoarded. If you know someone who is ill, copy and paste the part they need, or print up the article, and mail it to them (anonymously, might be a good idea in a lot of cases). Also, send a page or three of a print out of the titles and URLs and a typed message (again anonymously) leading to this post to your doctor. Something simple, like Want to know more? Visit here!and give the URL. Im hoping that in return for the hours I spent collecting this, you will give me a present in return- mailing this out and telling others. By spreading knowledge to help others, you give them power over their own lives! Knowledge is power! And the truth will set us free (to smoke our pot in peace!) - Storm Crow
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Granny Storm Crow's MMJ Reference List- January 2012

Endocannabinoid signaling and epidermal differentiation. (abst 2011)

ADD/ ADHD ADHD by Ryan P (anecdotal - no date)

(abst 1986) (no date - 2008)

How Cannabis Compares to other treatments Recipe For Trouble

(anecdotal/ news - 2002 )

Fitness to drive in spite (because) of THC

(full - 2008) (abst - 2008) (news - 2008)

Autism, ADD, ADHD and Marijuana Therapy

Why I Give My Autistic Son Pot, Part 4

Abuse potential of dronabinol (Marinol).

(abst 1998) (full - 1990)

Relative Addictiveness of Various Substances

Merck Manual - Marijuana (Cannabis)

(excerpt - 2008) (news 2008)

Study of 4000 indicates marijuana discourages use of hard drugs.

Calling B.S. on the Idea of 'Marijuana Addiction'

When Your Kid Smokes Pot

The Surprising Effect Of Marijuana On Morphine Dependence

Active Ingredient In Cannabis Eliminates Morphine Dependence In Rats

Four percent of adults worldwide using cannabis

(full 2010) (news - 2010)

Brain Chemicals Mimic Marijuana

Endocannabinoids and Vascular Function

(full - 2000) (abst - 2000)

Cardiovascular effects of endocannabinoids--the plot thickens.

Role of Endogenous Cannabinoids in Synaptic Signaling

Manipulation of the endocannabinoid system by a general anaesthetic.

http://www.cmaj.ca/cgi/content/full/173/4/357?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=end ocannabinoid&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=date&resourcetype=HW CIT

CB1 cannabinoid receptor-mediated modulation of food intake in mice

Endocannabinoids, feeding and suckling from our perspective

Not Too Excited? Thank Your Endocannabinoids

Experimental autoimmune encephalomyelitis disrupts endocannabinoid-mediated neuroprotection (full - 2006)

Weight Control in Individuals With Diabetes

2-AG + 2 new players = forecast for therapeutic advances.

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6VRP-4RFCCVN4&_user=10&_coverDate=12%2F26%2F2007&_rdoc=1&_fmt=high&_orig=gateway&_origin=gateway& _sort=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=9ee f728e35c89b5764ef2d27c0cdffe9&searchtype=a

CB2 receptors in the brain: role in central immune function

(full - 2007) (full - 2007)

Opposing Actions of Endocannabinoids on Cholangiocarcinoma Growth

Cannabinoid receptors and the regulation of bone mass

Dysregulation of the endocannabinoid system in obesity.

(abst 2008) (news - 2008) (news - 2008)

Understanding the effects of endogenous cannabinoids

Marijuana-Inspired Painkiller? New Chemical Pathway Discovered

Endogenous cannabinoid signaling is essential for stress adaptation

Endocannabinoid signalling: has it got rhythm?

The endocannabinoid system and cancer: therapeutic implication

Endocannabinoid 2-arachidonoylglycerol protects neurons against -amyloid insults. (abst 2011)

The major central endocannabinoid directly acts at GABA(A) receptors.

New metabolic pathway for controlling brain inflammation

2-AGE/ 2-ARACHIDONYL GLYCERYL ETHER/ NOLADIN ETHER

Pass the Doobie, pops

Inflammation and aging: can endocannabinoids help?

CN BC: Expert Testifies Cannabis Helps Slow Aging (news - 2008)

Older Adults' Pot Use Up

(news - 2010) (news - 2010)

Marijuana Use By Seniors Goes Up As Boomers Age

Pot Breaks the Age Barrier

AIDS see HIV