Scribd Logo
Upload

Welcome to Scribd!

  • 789 views

    A: Hydrolyzed To Active Drug: Cebu Normal University - College of Nursing Drug Study

    Uploaded by

    Maki Dc
    This document summarizes key information about the antibiotic drug ceftriaxone sodium (trade name Rocephin). It provides details on the drug's generic and trade names, dosage, administration routes, mechanism of action, indications, contraindications, adverse reactions, interactions, and nursing responsibilities related to administration and monitoring. The patient in this case was given ceftriaxone for septicaemia and bone and joint infections. Precautions are needed for patients with renal or liver dysfunction, during pregnancy or lactation.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd

    A: Hydrolyzed To Active Drug: Cebu Normal University - College of Nursing Drug Study

    Uploaded by

    Maki Dc
    789 views1 page
    This document summarizes key information about the antibiotic drug ceftriaxone sodium (trade name Rocephin). It provides details on the drug's generic and trade names, dosage, administration routes, mechanism of action, indications, contraindications, adverse reactions, interactions, and nursing responsibilities related to administration and monitoring. The patient in this case was given ceftriaxone for septicaemia and bone and joint infections. Precautions are needed for patients with renal or liver dysfunction, during pregnancy or lactation.

    Original Title

    ceftriaxone

    Copyright

    © Attribution Non-Commercial (BY-NC)

    Available Formats

    DOC, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    This document summarizes key information about the antibiotic drug ceftriaxone sodium (trade name Rocephin). It provides details on the drug's generic and trade names, dosage, administration routes, mechanism of action, indications, contraindications, adverse reactions, interactions, and nursing responsibilities related to administration and monitoring. The patient in this case was given ceftriaxone for septicaemia and bone and joint infections. Precautions are needed for patients with renal or liver dysfunction, during pregnancy or lactation.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    789 views1 page

    A: Hydrolyzed To Active Drug: Cebu Normal University - College of Nursing Drug Study

    Uploaded by

    Maki Dc
    This document summarizes key information about the antibiotic drug ceftriaxone sodium (trade name Rocephin). It provides details on the drug's generic and trade names, dosage, administration routes, mechanism of action, indications, contraindications, adverse reactions, interactions, and nursing responsibilities related to administration and monitoring. The patient in this case was given ceftriaxone for septicaemia and bone and joint infections. Precautions are needed for patients with renal or liver dysfunction, during pregnancy or lactation.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    You are on page 1of 1

    Cebu Normal University College of Nursing DRUG STUDY

    Drug Data Generic Name ceftriaxone sodium Trade Name Rocephin Patients Dose 2g IVTT every 12 hours ANST (-) Minimum Dose 250 mg OD IM or IV Maximum Dose 2g IVTT every 12 hours Contents ceftriaxone Availability Powder for injection : 250, 500 mg, 1, 2 g Injection : 1,2 g Routes of administration IV, IM

    Classification Pharmacologic Class: third generation cephalosporin

    Mechanism of Action Pharmacokinetics Bactericidal: Inhibits synthesis of bacterial cell wall, causing cell death A: hydrolyzed to active drug in GI mucosa

    Indication General Indications Lower respiratory tract infections caused by S. pneumoniae, H. parainfluenzae, H. influenzae UTIs caused by E. coli, K. pneumoniae Gonorrhea caused by neisseria gonorrhoeae Intrabdominal infections caused by E. Coli and K. Pneumonia Septicemia caused by E. Coli, S. Pneumonia, H. Influenzae, S. Aureus, K. Pneumonia Bone and joint infections caused by S. Aurues, streptococcus, P. Mirabilis, E. Coli, K. Pneumonia, N. meningitidis Patients Actual Indication This drug was given to the patient for septicaemia and bone and joint infections.

    Contraindications Contraindications Hypersensitivity to cephalosporins and related antibiotics or penicillins.

    Adverse Reactions CNS: Headache, dizziness, lethargy, paresthesias GI: Nausea, vomiting, diarrhea, anorexia, abdominal pain, flatulence, pseudomembranou s colitis, liver toxicity GU: Nephrotoxicity Hematologic: Bone marrow depression: decreased WBC, decreased platelets, decreased Hct Hypersensitivity: Ranging from rash to fever to anaphylaxis, serum sickness reaction Local: Pain, abscess at injection site; phlebitis, inflammation at IV site Other: Superinfections, disulfiram-like reaction with alcohol

    Nursing Responsibilities
    Before Determine history of hypersensitivity to cephalosporins, penicillins and other drugs prior to administration Observe the 15 RIGHTS of drug administration Perform C and S test prior to first dose

    Therapeutic Class: Antibiotic, antiinfective

    D: widely distributed in body tissues and fluids, crosses placenta, enters breast milk M: hepatic E: bile, urine Onset: IV: rapid IM: 30 min Peak: IV: immediate IM: 1.5-4 hr Duration : IV: 15 18 hr IM: 15 18 hr Drug Half Life: 5 10 hr

    Precautions Use cautiously with renal failures, lactation and preganancy.

    Assess history: Liver and kidney


    function test, culture of affected area, sensitivity tests

    dysfunction, lactation, pregnancy

    Check skin status, liver and kidney


    During Check for manufacturers inserts for specific details. Stability of reconstituted and diluted solution depends on diluents, concentration and type of container.

    Drug interactions Aminoglycosides - increased toxicity Oral anticoagulants increased bleeding effects Alcohol disulfiram-like reactions if taken 72 hours after administration of ceftiaxone

    Pregnancy Risk Category: B

    Do not mix with other antimicrobial

    drug. Protect drug from light. Avoid alcohol while taking this drug and for 3 days after. Have vitamin K available in case of hypoprothrombenimia occurs After Monitor ceftriaxone blood levels in patients with renal and hepatic impairment. Discontinue if hypersensitivity occurs. Advise patient to report severe diarrhea, difficulty of breathing, unusual tiredness of fatigue Report if theres pain at injection site.

    Warn patient that this drug should not


    be used to self-treat
    Source: ww.drugguide.com

    Source: ww.drugguide.com

    Source: ww.drugguide.com

    Source: ww.drugguide.com

    Source: ww.drugguide.com

    Source: ww.drugguide.com

    Source: ww.drugguide.com

    You might also like

    pFad - Phonifier reborn

    Pfad - The Proxy pFad of © 2024 Garber Painting. All rights reserved.

    Note: This service is not intended for secure transactions such as banking, social media, email, or purchasing. Use at your own risk. We assume no liability whatsoever for broken pages.


    Alternative Proxies:

    Alternative Proxy

    pFad Proxy

    pFad v3 Proxy

    pFad v4 Proxy