Obstetric Hemorrhage

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Obstetric Hemorrhage

Abike James MD Assistant Clinical Prof. Obstetrics and Gynecology University of Pennsylvania

Third Trimester Bleeding


A 32 yo G2P1 presents at 36 weeks complaining of bright red vaginal bleeding. Upon further questioning she does admit to having had some light bleeding on 1 to 2 occasions last week. Her previous pregnancy was delivered at term by a Classical Cesarean Section for footling breech presentation.

Differential Diagnosis?
Placenta Previa Uterine Rupture Placental Abruption Vasa Previa Laceration Vaginal mass

Placenta Previa
Painless third-trimester bleeding Complicates 4-6% pregnancies between 10 and 20 wks, 0.5% pregnancies >20 weeks Risk factors
Increasing parity, maternal age, prior c/s, curettages for sabs/tabs

Placental tissue overlying the internal os. Types?


Complete previa (20-30%) Partial previa (does not completely cover) Marginal (proximate to os)

Management: pelvic rest, u/s, IV, T+S, C/S

Associated Conditions
Placenta accreta, increta, percreta
Risk inc w/ inc no. of prior c/s (50% risk in pt w/ previa and 2 prior c/s)

Vasa Previa
Vessels traverse the membranes in the lower uterine segment in advance of the fetal head. Rupture can lead to fetal exsanguination

Uterine Rupture
Associated with Prior c/s Rates of uterine rupture?
Spontaneous rupture (no c/s history): 1/2000 (0.05%) Low Transverse: 0.5%-1%risk rupture, VBAC 80% success rate Classical C/s: 10% risk rupture, schedule amnio/c/s ~37 weeks.

Placental Abruption
Premature separation of placenta Painful third-trimester bleeding Risk Factors
smoking, trauma, HTN cocaine, pprom, polyhydramnios, multiples

Trauma evaluation
bleeding, contractions, abdominal pain and NRFHT in 4hrs

U/s misses up to 50% of abruptions Management: IV, T+X, Continuous monitoring, c/s vs. vag delivery

Case Contd
U/s reveals active, vertex fetus. Placenta anterior and free of os. Pt having contractions q 2-3 minuters. Bleeding increases. BP drops from 110/60 to palpable systolic pressure of 70. FHT drops from 120 to 90 bpm. What do you do???

Post Partum Hemorrhage


A 34yo G6P6 patient at term has just delivered a 4000gm infant after second stage of labor lasting 3 hours. The placenta delivered spontaneously and the patient is bleeding briskly. What is average EBL w/ SVD?
500cc

What is average EBL w/ C/S?


1000cc

Classes of Hemorrhage
Class 1
<900cc Minimal symptoms

Class 2
1200-1500cc Tachycardia, tachypnea

Class 3
1800-2100cc Overt Hypotension, cold, clammy skin

Class 4
2400cc Shock, absent BP

Management
Fluids
Crystalloid, open wide/bolus

Labs
Cbc, coags, fibrinogen

Transfuse PRPCs FFP


Larger vol (250cc/unit, all coagulation factors)

Cryopercipitate
Smaller volume (20cc/unit, many coagulation factors)

Differential Diagnosis
Atony Uterine inversion Laceration (cervical, vaginal) Retained Placenta

Uterine Atony
Risk factors
multiparity, multiple gestation, macrosomia, abruption, retained POCs, placenta previa, induction (prolonged pitocin)

Management
Bimanual exam/massage IV acess/fluids Oxytocin, methergine 0.2mg IM, Hemabate 250mcg IM, misoprostol 800 to 1000mcg rectally

Laparotomy
Uterine artery ligation B Lynch Hysterectomy

UAE

Uterine Inversion
Inverted fundus extends beyond cervix (looks beefy red) Stop pitocin if infusing Replace uterus Relaxants if necessary (terbutaline, MgSo4, Nitrogylcerin) Anesthesia Laparotomy

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