Obstetric Hemorrhage
Obstetric Hemorrhage
Obstetric Hemorrhage
Abike James MD Assistant Clinical Prof. Obstetrics and Gynecology University of Pennsylvania
Differential Diagnosis?
Placenta Previa Uterine Rupture Placental Abruption Vasa Previa Laceration Vaginal mass
Placenta Previa
Painless third-trimester bleeding Complicates 4-6% pregnancies between 10 and 20 wks, 0.5% pregnancies >20 weeks Risk factors
Increasing parity, maternal age, prior c/s, curettages for sabs/tabs
Associated Conditions
Placenta accreta, increta, percreta
Risk inc w/ inc no. of prior c/s (50% risk in pt w/ previa and 2 prior c/s)
Vasa Previa
Vessels traverse the membranes in the lower uterine segment in advance of the fetal head. Rupture can lead to fetal exsanguination
Uterine Rupture
Associated with Prior c/s Rates of uterine rupture?
Spontaneous rupture (no c/s history): 1/2000 (0.05%) Low Transverse: 0.5%-1%risk rupture, VBAC 80% success rate Classical C/s: 10% risk rupture, schedule amnio/c/s ~37 weeks.
Placental Abruption
Premature separation of placenta Painful third-trimester bleeding Risk Factors
smoking, trauma, HTN cocaine, pprom, polyhydramnios, multiples
Trauma evaluation
bleeding, contractions, abdominal pain and NRFHT in 4hrs
U/s misses up to 50% of abruptions Management: IV, T+X, Continuous monitoring, c/s vs. vag delivery
Case Contd
U/s reveals active, vertex fetus. Placenta anterior and free of os. Pt having contractions q 2-3 minuters. Bleeding increases. BP drops from 110/60 to palpable systolic pressure of 70. FHT drops from 120 to 90 bpm. What do you do???
Classes of Hemorrhage
Class 1
<900cc Minimal symptoms
Class 2
1200-1500cc Tachycardia, tachypnea
Class 3
1800-2100cc Overt Hypotension, cold, clammy skin
Class 4
2400cc Shock, absent BP
Management
Fluids
Crystalloid, open wide/bolus
Labs
Cbc, coags, fibrinogen
Cryopercipitate
Smaller volume (20cc/unit, many coagulation factors)
Differential Diagnosis
Atony Uterine inversion Laceration (cervical, vaginal) Retained Placenta
Uterine Atony
Risk factors
multiparity, multiple gestation, macrosomia, abruption, retained POCs, placenta previa, induction (prolonged pitocin)
Management
Bimanual exam/massage IV acess/fluids Oxytocin, methergine 0.2mg IM, Hemabate 250mcg IM, misoprostol 800 to 1000mcg rectally
Laparotomy
Uterine artery ligation B Lynch Hysterectomy
UAE
Uterine Inversion
Inverted fundus extends beyond cervix (looks beefy red) Stop pitocin if infusing Replace uterus Relaxants if necessary (terbutaline, MgSo4, Nitrogylcerin) Anesthesia Laparotomy