Dr. Amel - Corneal Ulcer With Descemetocele

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CASE REPORT

CORNEAL ULCER
WITH
DESCEMETOCELE
AMELIA SAFITRI RAMADHANI, MD
INTRODUCTION
Background

 Corneal ulcer is defined as a disruption of the


epithelial layer with involvement of the corneal
stroma (Reddy et al., 2005)
 Cornealulcers have the potential to cause
devastating loss of vision, often rapidly (Tuli,
Sonal, 2012)
 Cornealulcers are the second most-common cause
of preventable blindness after cataract in tropical
developing country (Bandyopadhyay, et al., 2012)
PURPOSE

 Tofurther study the management of


corneal ulcer to reduce the development
of its complications
REVIEW ARTICLE
ANATOMY OF CORNEA

(Vaughan dan Asbury, 2010)


PATHOPHYSIOLOGY

(Bhavsar, Yogini, 2010)


Most common pathogens : Bacteria
Pseudomonas aeruginosa
Staphylococcus aureus
Streptococci
Guidelines for the Management of Corneal Ulcer, WHO
2004
Treatment for Uncomplicated Corneal
Ulcer

 Specific treatment for the cause


Local and systemic antibiotics
 Non-specific supportive therapy
Cycloplegic drugs, systemic analgesics and anti-
inflammatory drugs, vitamins
 Physical and general measures
Hot fomentation, pad and bandage, rest, and good diet

Khurana AK, 2007


Treatment for Non-Healing Corneal
Ulcer

 Removal of any known cause of non-healing


ulcer
 Mechanical debridement of ulcer to remove
necrosed material by scraping floor of the ulcer
with spatula
 Cauterisation of the ulcer
 Peritomy
Treatment for Impending Perforation

 No strain. The patient should be advised to


avoid sneezing, couging, and straining during
stool etc.
 Pressure bandage
 Lowering of IOP
 Tissue adhesive glue such as cynoacrylate
 Conjunctival flap
 Bandage soft contact lens
 Penetrating therapeutic keratoplasty
Treatment for Perforated Corneal
Ulcer

 Depending upon the size of perforation and


availability, measures like use of tissue adhesive
glues, covering with conjunctival flap, use of bandage
soft contact lens or therapeutic keratoplasty should be
undertaken. Best is an urgent therapeutic
keratoplasty
CASE
PRESENTATION
IDENTITY

 Name : Mr. Gimun


 Age : 77 years old
 Address : Bluru Kidul, Sidoarjo
ANAMNESIS
 Chief complaint : appearance of the black spot and pus on
the LE
 The patient and his daughter came to the outpatient
clinic and complained about the appearance of a black
spot and pus on the LE, followed by ocular pain and
tearing since one day before. The patient’s daughter also
complained about the appearance of white matter on the
patient’s LE since 2 months, followed by redness of LE
and blurred vision.
 Hospitalized in BKMM for two times (on November and
early December 2014) and referred into RSUD dr.
Soetomo on December 23rd – 29th 2014 because of the
HISTORY OF PAST ILLNESS

 RE was blind since 20 years ago, with the


same symptoms as the current LE. The
patient said that the doctor was performed a
surgery, but he doesn’t remember what kind
of surgery. Since that time, the RE was blind.
 No history of DM, Hipertension
PHYSICAL EXAMINATION

 Visual Acuity

 Right Eye : LP -

 Left Eye : 1/300 (hand movement)

 Intraocular Pressure

 Right Eye : Can’t be evaluated

 Left Eye : Can’t be evaluated


ANTERIOR
RIGHT EYE LEFT EYE
SEGMENT
Ptysis Bulbi (+)
Edema -, Spasm - Palpebra Edema -, Spasm -
Hyperemia +
Hyperemia +
Conjunctiva Subconjunctival
(minimal)
bleeding (+)
Hazy +, Fl test was
Hazy +, Fl test +, not performed,
Cornea
Neovascularization + Descemetocele +,
Neovascularization +
Anterior
Difficult to be Hypopion ½ of the
Chamber
evaluated anterior chamber
Depth
Difficult to be Difficult to be
Iris
evaluated evaluated
Difficult to be Difficult to be
Pupil
evaluated evaluated
Difficult to be Difficult to be
Lens
evaluated evaluated
FUNDUSCOPY

RIGHT EYE LEFT EYE


Can not be Can not be
evaluated evaluated
SCRAPPING (January 21st, 2015)

 PMN : many
 MN : few
 Bacteria : negative
 KOH : negative
ULTRASONOGRAPHY (January 22nd, 2015 by Sauli Ari, MD.
Ophthalmologist)

 Conclusion: PVD
LABORATORY & RADIOLOGY
FINDINGS (January 23rd, 2015)

 Kalium
: 2,7 mmol/L (N: 3,5 – 5,5
mmol/L)

 Chest
X-Ray : Cardiomegaly with
prominent aortic knob
CONSULTATION

 Cardiology Dept.
Saat ini di bidang Kardiologi kami dapatkan pasien dengan hipertensi
stage I JNC VII tanpa tanda gagal jantung akut. Saran: Amlodipine 5mg
–0–0
 Internal Medicine Dept.
Saat ini di bidang IPD jami dapatkan penderita dengan hipokalemia
dengan penyebab yang masih memerlukan evaluasi. Saran :
1.Diet TKTP 2100 Kkal/hari ekstra buah
2.Koreksi dengan drip KCl 25 meq dalam PZ 500 cc selama 12 jam
3.KSR 3x1 tablet
4.Tidak ada kontraindikasi untuk dilakukan tindakan di bidang TS
TEMPORARY PROBLEM LIST

 Black spot and pus on the LE


 LE ocular pain and tearing
 White matter on the black part of the LE since 2 months ago, followed by
redness of the LE and blurred vision
 Blind RE since 20 years ago, with the same symptom as the LE
 Visual acuity of RE : LP (-) and LE : 1/300 bad projrction illumination
 conjunctival hyperemia on the left eye, hazy left eye’s cornea due to the
infiltration, thinning process as descemetocele, and neovascularization on the
left eye’s cornea, also hypopion within the left eye’s anterior chamber
 Iris prolapse on the 6th day
 USG : LE PVD
PERMANENT PROBLEM LIST

 LECorneal Ulcer with Hypopion + Descemetocele + Iris


Prolapse
 RE Blind Eye
DAILY FOLLOW UP
January 21st, 2015

VISUAL ACUITY
RE : LP (-) LE : 1/300 bad PI
LE anterior segment : Descemetocele 3 x 3
mm
Hypopion ½ of anterior
chamber
Advice from Randi Montana, MD.
Ophthalmologist:
• Hospitalized
• Ceftriaxone 2x1 gram i.v.
• Na Diclofenac 2x50 mg p.rn.
• Vigamox e.d. ½ jam dd gtt I OS
• Tobramycin e.d. OH dd gtt I OS
• Atropin e.d. 2 dd gtt I OS
• Suspect bacterial infection
January 23rd, 2015

VISUAL ACUITY
RE : LP (-) LE : LP (+)
LE anterior segment : Descemetocele (+) 3 x 5 mm
Hypopion ½ of anterior chamber
Advice from Eddyanto, MD. Ophthalmologist
Prepare for the LE Cryotherapy + AMT + BCL (on January
27th, 2015)
January 25th, 2015

VISUAL ACUITY
RE : LP (-) LE : LP (+)

LE anterior segment : Descemetocele (+) 3 x 5


mm
Hypopion 1/5 of anterior
chamber
January 26th, 2015

VISUAL ACUITY
RE : LP (-) LE : LP (+)

LE anterior segment : Descemetocele (+) 3 x 5 mm


Hypopion (-)

Result from gram staining and aerobic culture : no


pathogen was found
VISUAL ACUITY
RE : LP (-) LE : LP (+)

LE anterior segment : Descemetocele (+) 3 x 5


mm
Iris prolapse (+)
Hypopion (-)
LE AMT + CRYOTHERAPY + BCL
POST OPERATIVE TREATMENT

 Chloramphenicol 3 x 500 mg
 Vigamox e.d. ½ OH dd gtt I OS
 Tobro e.d. OH dd gtt I OS
 Na Diclofenac tab. 2 x 50 mg p.c.
 Eye tapping and bandage (can be opened after three days)
THANK YOU

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