RTC Shock

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Shock

Kenneth Stahl MD FACS

OBJECTIVES
1. Define shock and apply to clinical situations
2. Recognize clinical presentations of shock
3. Learn the cellular mechanisms and sub-cellular
biochemistry of shock
4. Learn the degrees and grades of shock
5. Understand diagnostic tests used in patients with
shock
6. Learn treatments for various types of shock
5? of Types of Shock
1. Hypovolemic shock
2. Cardiogenic shock
Septic/neurogenic
3. Distributive shock → ?
shock
4. Obstructive shock
5. Endocrine shock
3? Stages of Shock
1. Pre-shock (warm shock or compensated shock): rapid
compensation for diminished tissue perfusion by
homeostatic mechanisms

2. Shock: compensatory mechanisms become overwhelmed


and signs and symptoms of organ dysfunction
appear - tachycardia, dyspnea, restlessness,
diaphoresis, metabolic acidosis, oliguria, cool
clammy skin

3. End-organ dysfunction : irreversible organ damage, no


urine output (anuria and acute renal failure),
acidemia ,decreases the cardiac output ,coma and
patient death
Shock - Clinical Presentation
1. Anxiety, restlessness, altered mental state (↓cerebral
perfusion and subsequent hypoxia)
2. Hypotension (↓cardiac output, ↓stroke volume)
3. Pulse (rapid, weak, thready)
4. Cool, clammy, mottled skin (vasoconstriction,
hypoperfusion)
5. Oliguria (↓renal perfusion)
6. Hyperventilation (sympathetic nervous system
stimulation and acidosis)
7. Fatigue (late)
8. Absent pulse in tachyarrhythmia
Shock
Cellular Pathophysiology
Inadequate tissue perfusion
Cellular hypoxia
Energy deficit Anaerobic Metabolism
Vasoconstriction Lactic acid accumulation (↓pH)
↓ Pre-capillary Metabolic acidosis
sphincters
Cell membrane dysfunction
Peripheral blood (↓NaK cell membrane pump) K+ Efflux
pooling
Intracellular lysosome release Na+ H20 Influx
Buildup of intracellular toxins Cellular swelling
↓Tissue
Capillary endothelium damage
perfusion
↓Urine Cell dysfunction and apoptosis
output
Patient death
Shock Diagnostic Work Up
1. There is NO single diagnostic test for shock
2. Hypotensive trauma patient is in shock
3. Physical Examination
4. Patient history (trauma/injury, sepsis, MI)
5. FST (sometimes)
6. Swan-Ganz catheter (late, not very useful)
7. Pro-BNP (Cardiogenic shock)
8. EKG (arrhythmia)
Hemorrhagic Shock
Mechanisms
Blood Loss
4 Classes of Shock
Class I Class II Class III Class IV
Volume Loss 750 – 1500 -
<750 cc 1500 cc 2000 cc >2000cc

% Blood
<15% 15-25% 25-40% >40%
volume
∆ Blood
 to none ↓ to none ↓↓ ↓↓ to
Pressure absent
∆ Heart Rate 100 - 120 -
<100 >140
beats/minute 120 140

∆ Pulse none to ↑ ↓ ↓↓ ↓↓ to
Pressure DBP absent
∆ CNS none to slightly mildly anxious to confused
anxious anxious confused to lethargic

∆ Respiratory normal 20-30 30-40 >40


rate
Treatment of Hemorrhagic Shock

1. RECOGNIZE patient is in shock


2. ATLS (ABCDE’s)
3. Volume, volume, volume
4. Surgical – stop bleeding, correct injury
5. Re-establish normal hemodynamics
6. Re-establish urine flow
Obstructive Shock

1. Cardiac Tamponade
2. Tension Pneumothorax
3. Mediastinal Crushing Injury
(caval obstruction)
4. Aortic dissection (obstruction)
5. Mediastinal Torsion
6. Pulmonary Embolism
Diagnosis of Obstructive Shock
1. RECOGNIZE patient is in shock
2. Mechanism of Injury
3. Physical examination
4. Chest x-ray, FST, 2-D Echo
Distributive Shock
Neurogenic/Septic Shock
1. Low systemic vascular resistance (SVR)
2. Spinal chord trauma (neurogenic shock)
3. Gram negative sepsis
Treatment Distributive Shock
Neurogenic/Septic Shock
1. Control systemic vascular resistance (SVR)
2. Hemodynamic support
3. Source control (drain abscess, ∆ CVP lines)
4. Stabilize spinal chord (neurogenic shock)
5. Treat gram negative sepsis (broad
spectrum antibiotics)
Caridogenic Shock

1. Valve dysfunction (acute, chronic) AS,AI,MR


2. Prosthetic valve dysfunction (thrombus,
dehiscence)
3. LV failure (Frank-Starling curves)
4. Arrhythmia (Ventricular, Atrial)
5. Aortic dissection (acute AI, tamponade, MI)
Endocrine Shock
1. Acute adrenal deficiency
2. Hypothyroidism
3. Hyperthyroidism (thyrotoxicosis)
Summary
1. Shock is an circulatory system abnormality
that results in inadequate tissue perfusion
2. Hypovolemia is the cause of shock in the
majority of trauma patients
3. Hypovolemic shock has 4 stages from mild to
fatal
4. There is NO DIAGNOSTIC test for shock
5. The most important and first treatment for
shock is RECOGNIZING patient is in shock

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