Poliomyelitis
Poliomyelitis
Poliomyelitis
ROLL NO. 3
B.Ph.T-final prof.
•Poliomyelitis commonly
called as polio is an endemic
and epidemic infectious viral
disease caused by polio
virus.
•Poliomyelitis is derived
from Greek word
•Polio meaning “grey”
•Myelon means “spinal cord”
•itis denotes inflammation
oThis is a viral
infection of the
anterior horn cell of
the spinal cord or
nerve cells of the brain
stem, resulting in
temporary and
permanent paralysis.
oThere is flaccid
paralysis without a
sensory loss.
When the polio vaccine was not
introduced, poliomyelitis was
found in all countries. But with
the invention and use of polio
vaccine there is total eradication
of disease from many developed
countries.
In India ,in 2003-225 cases
reported
2018-33 cases
National immunization
programme is carried out by govt.
of India to eradicate polio.
Under this, all the children under
the age of 5 years are
administrated with oral polio
vaccine(OPV),free of cost.
VIROLOGY: The polio virus is
a spherical virus of 25-27 microns
in diameter.
In a cold environment, it can live
in water for 4 months and in feces
for 6 months.
Poliovirus has three serotypes:
TYPE I- BRUNHILDE
TYPE II-LANSING
TYPE III-LEON
PERIOD OF COMMUNICABILITY: 7-10 days before and after
onset of symptoms.
AGE OF ONSET: It is a disease of infancy and childhood .
common in children less than 5 years of age
SEX AFFECTED MOST : MALE : FEMALE ratio = 3 : 1
ENVIRONMENTAL FACTORS: likely to occur during rainy
season.
Sources: contaminated water, food and flies
Overcrowding and poor sanitation.
RISK FACTORS: -immune deficiency
Malnutrition
Tonsillectomy
Physical activity immediately following the onset of paralysis.
Skeletal muscle injury due to i.m. injection or in child on
cortisone therapy.
INCUBATION PERIOD:- 7-14 DAYS
FECAL-ORAL ROUTE: DROPLET INFECTION:
(main route) (Usually occurs in the
Infection may spread acute phase of disease)
directly through Virus is present in the
contaminated fingers throat.
where the hygiene is poor Close personal contact
or indirectly through with infected person may
contaminated water, food, facilitate droplet spread.
flies etc…
ACUTE PHASE CONVALESCENT OR CHRONIC OR
(0-2 or 3 weeks) RECOVERY PHASE RESIDUAL PHASE
Child is restless and (3 weeks -12months) (12-18 months)
irritable due to pain and follows the acute phase no hope of recovery.
muscle tenderness where the damage to the Damage to ant. Horn
together with spasm, neurons is less resulting cells of spinal cord or
joints are also involved. either in spontaneous brain stem leading to
General malaise, recovery (upto 5 weeks) of paralysis ranging from
headache and bowel upset the affected muscle or minimal degree to
may be present with low cause various degree of complete paralysis.
grade fever and sore paralysis. Bones and joints are
throat. The rate of recovery slows affected due to long term
Involvement of brain is down, and hardly of contractures.
little or absent. continues beyond 6-12 Paralysis may lead to
months. imbalance and deformities
INAPPARENT OR SUBCLINICAL INFECTION
Seen in 95% cases of polio infection
Recovery is fast and there is no such presenting symptoms.
Recognition is only by virus isolation.
ABORTIVE POLIO OR MINOR ILLNESS
Seen in 4-8% of polio infection
Causes self -limiting illness and recovers fast.
Minor symptoms include: - sore throat
-malaise
-headache
-GIT upset(diarrhea)
-low grade fever
-muscle pain and tenderness
NON-PARALYTIC POLIO
Occurs in 2-3% cases of polio.
The damaged neurons undergo
regeneration and the recovery occurs.
The symptoms include:
-stiffness and pain in neck and back.
-high grade fever
-malaise
-nausea
-vomiting
-muscle weakness
-upper respiratory tract infection
-joint pain
-diarrhea or constipation
-excessive tiredness and fatigue
PARALYTIC POLIOMYELITIS
Seen in less than 1% cases.
The signs and symptoms vary acc. To the duration and severity of
damage. It includes:
-asymmetrical flaccid paralysis is the prominent sign at this phase of
the disease.
-onset is associated with fever.
-meningeal irritation i.e. stiffness of neck and back muscles
-Tripod sign is the peculiar feature of polio i.e. the child finds difficulty
in sitting and sits by supporting hands at the back and by partially
flexing the hips and knees.
-descending type of paralysis.
-deep tendon reflexes are lost but sensation is intact.
-In severe cases, there is involvement of cranial nerves leading to bulbar
and bulbospinal form of paralysis. In this type of paralysis, there is facial
asymmetry, difficulty in swallowing, resp. insufficiency.
-leads to the weakness of muscles innervated --difficulty in breathing, speaking and
by the dead neurons. swallowing
-muscle atrophy occurs. -facial weakness
-muscle becomes weak, floppy and poorly -abnormal resp. rate, depth and rhythm
controllable and finally paralyzed.
-fever and muscle pain.
-deep tendon reflexes-absent or diminished
-sensation is intact.
-asymmetrical paralysis
19% CASES
It can lead to paralysis of the arms and legs and may also
effect swallowing and heart function.
Facial weakness
IN THE EARLY STAGE
The child is febrile, with rigidity of the neck and tender
muscles; there is diffuse muscle paralysis.
Involvement of affected muscle is asymmetrical.
It occurs commonly in lower limbs because the anterior
Horn cells of the lumbar enlargement of the spinal cord are
affected often.
Muscles affected are: quadriceps, although in some cases it
is partially paralyzed
Tibialis anterior: complete paralysis
Opponens pollicis
If motor neurons of medulla are affected, it results in
bulbospinal polio which is life-threatening polio. It involves
cardiovascular and respiratory centers and may be fatal .
Paralysis may result in wasting, weakness and deformities of limb.
The deformities result from imbalance between muscle of
opposite groups at a joint, or due to action of gravity on the
paralyzed limb.
Various deformities are:-
1. Hip is in flexion, abduction and external rotation
•RELAXATION
•FIXATION
•SUPPORT
•TRACTION
•RANGE
•SPEED AND
DURATION
•To improve circulation.
•FREQUENCY: 50-100Hz