Application of Drug Information Retrieval and Storage

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Drug information

retrieval and storage


•Prepared by:
•Iffa Qazi
•Hafsa khan 
•Umm e Habiba
•Tuba Abrar
•Sakina
•Tahira Khansa
•Neha Fatima 
•Rbia
Systematic process of collecting and cataloging
data so that they can be located and displayed
on request.

Information
storage and Computers and data processing techniques have

retrieval
made possible to access the high-speed and
large amounts of information for government,
commercial, and academic purposes. 

A branch of computer or library science relating


to storage, locating, searching and Selecting,
upon demand, relevant data on a given subject.
Basic It can refer to a place like a storage room
concept where paper records are kept. It can also
of refer to a Storage device such as a
computer hard disk, CD, DVD, or similar
informati device which can hold data.
on
storage 
Storage keeps data and information for use
in the future. Common storage mediums are:

Types of 1.Hard Drive

Informati
2.Floppy Disk
on
storage 3.CD & DVD 
media 
4.USB Flash Drive
Hard Drive

• It is always inside the computer.


• It stores all the programs that the computer needs to work. 
 Floppy Disk 

• It is a portable storage medium. 


• Put it into the computer save your information
CD & DVD 

• It is a portable storage. 
• It allows you to save information on it.
USB Flash
Drive

It holds more It is very


It is very easy
data than a small device
to carry .
floppy disk. than others.
Basic • An information retrieval system is an information

concept of
system, that is a system used to store Items of
information that need to be processed, searched,

Information
retrieved, and disseminated to various user populations”
(Salton, 1983)

Retrieval 
• Information retrieval can be divided into
several major constitutes which
Major include: 
Components of • Database 
IR  • Search mechanism 
• Language 
• Interface
Database 
A system whose base, whose key
concept is simply a particular way
of handling data and Its objective
is to record and maintain
information.
Search mechanism 

Information organized systematically that can be searched and retrieved


when a corresponding search mechanism is provided.

Search procedure can be categorized as basic or advance search


procedure.

Capacity of search mechanism determines what retrieval techniques will


be available to users and how information stored in databases can be
retrieved.
Information relies on language
when being processed,
transferred or communicated. 

Language 
Language can be identified as
natural language and controlled
vocabulary.
Interface regularly considered
whether or not an information
retrieval system is user Friendly. 

Interface  Quality of interface checked by


interaction mode.

Determines the ultimate success


of a system for information
retrieval.
Online systems

Informatio CD-ROM systems

n Retrieval
Systems  OPAC 

Web information Retrieval Systems


Online systems
• Online information retrieval systems allow the user
to search databases located remotely with the help
of the computer and telecommunication technology.
• Basic searching techniques 
• Advanced retrieval techniques 
Examples: Library of Congress, University of
Punjab Library
CD-ROM systems are usually searched
locally and it works if the systems are not
networked. 

Basic retrieval techniques are supported in


CD-ROM systems while advanced search

CD-ROM facilities are applied in limited scope.

systems The data which is stored on compact disc


(CD) can to read by any computer operating
systems and any CD-ROM drive.

Example: LISA
Online public access
First, OPACs contains
catalogs (OPACs) are
bibliographic information
traditional catalogs executed
about library resources.
in a different medium.

Second, OPACs can be


Different features of OPACs
considered as an extension
are 
of MARC records.

OPAC Third, OPACs support at


Examples: Library of least field searching,
congress catalogue. keyword searching and
Boolean searching. 

University of Punjab online


catalogue.
It deals with text as well as multimedia
information resources that are linked
with other documents and there is no
target user’s community as such.

Web
information Basically web is a platform where
anyone from anywhere can publish

Retrieval virtually any information, in any


language or in any format.

Systems 
Examples, Google, Alta Vista
Drugs information retrieval
systems:
As a drug moves along the path from discovery to the market and into worldwide
use, data and information about the agent are created and accumulate.

When this information is published, its value and usefulness to scientific,


professional, and patient communities becomes known.

Publication of research results at each step of the path is essential. The path of
drug development and marketing offers a structure that is useful to scientists and
practioners concerned with compounds of potential therapeutic value.
1.Preclinical Drug information:
At this point a compound is recognized and then considered for potential usefulness
pharmaceutical therapeutic or researchers will be both consumers of and
contributors to the data information-knowledge cycle that characterizes science

Initially, in the synthesis and purification phase of drug development, information


about the compound's chemistry and physical properties may be both sought and
created. 

Whether or not the compound has been of interest to other researchers may be
determined by searching public records of grant and contract awards and also by
searching resources that cover preliminary and early research results.
A)Physical and chemical data:

• AIDSDRUGS, Beilstein, CAS Registry, Chemcyclopedia, ChemFinder, Chemical


Abstracts, ChemlD plus, Chemindex plus and The Merck Index.
B)Patents: 

• U. S. Patent and Trademark Office Web Patent offer free WWW Databases access
http://www.uspto.gov/main/patents.htm, to a bibliographic patent database that
uses the most current patent classification system. 
• The Delphion Intellectual Property Network (IPN) is a research tool for patent
information. 
2.Phase IV Studies and Post
Marketing Drug Information:

During the Phase IV Studies and Post Marketing Drug Information stages a thorough
literature search is required to find material relevant to the clinical use of the drug. 

This will require not only searching the basic bibliographic databases such as Biological
Abstracts, EMBASE, IDIS, IPA, MEDLINE, and Science Citation Index, but also searching the
patent literature, using Patent and Trademark Office Web Patent Databases.
• The following bibliographic databases provide
access to the full span of life-science periodical
literature, including all stages of a compound's
development comprehensive assessments after
years of clinical use.
• BIOSISBIOSIS
continue • EMBASE 
• International Pharmaceutical Abstracts 
• MEDLINE 
• PubMed Central 
• Science Citation Index
Drug
Literature: 
• The concept of drug information service or drug
information center is an attempt to document drugs
by abstracting information about them.
• The information about drugs is collected from
various sources which are available. 
• In 1972 Walton et al modeled the drug literature as
a pyramid with the primary literature forming the
base of the pyramid, the secondary literature
interfacing and serving as a bridge from the primary
literature to reference works (tertiary literature).
• Primary Literature:

Primary literature contains the first written accounts of original research. 

In terms of size, the primary literature is probably larger than either the
secondary or tertiary literature. 

It is the original information presented by the author without any


evaluation by the second party, for example, articles published in journals,
dissertations, conferences, etc.
• Secondary Literature:

In this original information is


These include - Indexing
modified, condensed,
and Abstracting services,
commented upon by other
Evaluated Secondary Resources
persons like review articles,
and Internet search engines.
abstracts, text books, etc. 
• Tertiary Literature:
In this information is gathered from primary and secondary sources and arranged in such a manner to
give coupled information.

The tertiary literature is a distillation and evaluation of data and information first presented in such
primary literature sources as research reports, meeting presentations, and journal articles.

But just as characteristic, the tertiary is the most accessible, easiest to use, and perhaps the most used of
all information resources Information searches generally start with a perusal of books, reviews, and
handbooks. 

These include - Aggregated and linked references such as MICROMEDEX Systems and StatRef.
Save time, space, money.

Advantag Save effort, person-hours and greater efficiency 

es of
Computer Online Computerized services offer Term Searching of Fields,
Controlled vocabulary and Indexes.

ized
Literature
Online Computerized services offer Search Commands for Creating
search sets, Boolean operation, Word searching and Search limiting. 

Retrieval: Online Computerized databases offer Computerized greater Precision 

 
Qualitatively different kinds of searches are possible. 
Easier to assess quality of information found More cues:
authorship, institutional affiliation, reputation, references,…

Advantag Processing of search results: Sort, rank, report, export,

es of
integration with Intranet/portal,... 

Computer Highly Focused information that is actionable

ized
Literature They offer evidence for their claims. 

Retrieval: Provides great reading with a wealth of knowledge 


 
Broadened perspective
Most articles contained in journals include graphs,
tables, images & photographs, videos, etc., which help
illustrate the information being portrayed 

Advantages of
Computerized Unlike in the print copies days when you could only
access information physically in libraries, academic
Literature Ret journals online come with the option of free downloads
rieval:  which allow you to save material to your PC or
Smartphone 

Online journals are like encyclopedias, offering


information in large quantities to scholars. There's a
wide variety of databases to source information from,
but it's so much easier to access this information online
because all you need is a computer and internet. 
Academic journals include real life case
studies which are excellent sources of in-
depth information and knowledge. 
Advantages of
Computerized L
iterature Retrie
val:  Academic journals online come with several
research options, which helps widen
your scope. They allow you to explore both
quantitative and qualitative research, for
optimum results. With both, you can
analyze statistical data, opinions, verbal
data, etc. 
To call up data that has been stored in
RETRIEVAL computer system. 

USE OF
COMPUTERI
ZED When a user queries a database (a structured

RETRIEVAL: set of data held in a computer, especially one


that is accessible in various ways) the data are
retrieved into the computer first and than
transmitted to the screen.
USE OF COMPUTERIZED
RETRIEVAL:
Today computers provide us with powerful tools for drug information handling for
collection, organization, classification, retrieval and distribution.

Computers have been used since the late 1960s for the storage of large databases such as
library catalogues and bibliographic references.

Development of optical storage media such as CD-ROM has given us the possibility of
storing large quantities of text, graphics, pictures, and sound at a low cost.

These new optical memories can function as distributed stores for. Encyclopedias,


databases, books etc. This has stimulated the development of local information systems.
Computer based information
retrieval involves an interactive
dialogue between the enquirer and
databases.

COMPUTERI
ZED The computer matches any input
INFORMATI search in terms against its files, and
then displays any resulting
ON matches. 

RETRIEVAL:
These can then be printed out or
downloaded by the searcher.
These three aspects of computerized
information retrieval:
ASPECTS • library catalogues : it is a listing of all Items within a
OF library. In pre-computer times, library books were
COMPUTERI indexed in card catalogues which were cabinets
of drawers of index cards: author cards, title cards,
ZED and subject cards.
• Online Databases:  it  is a database accessible from
INFORMATI local network or the internet or stored locally on an
ON individual computer such as CD. Online databases
are hosted on websites, made available as software
RETRIEVAL as a service products accessible via a web browser.
• Databases on CD-ROM: It is a pre-pressed optical
(ICR): compact disc that contains data. Computers can
read but not to write or erase. CD-ROM ie, type od
read only memory.
There are number of types of databases:
• 1.Library catalogues: catalogues covering the
holdings (books, reports, journals, conference
proceedings, etc) of one or more library
• 2.Bibliographic databases: containing
TYPES OF bibliographic references, with or without
abstract.
DATABAS • 3.Reference databases: for example, current
ES: research projects, handbooks, encyclopedias,
product suppliers, etc.
• 4.Factual databases or data bank: containing
information, often in numerical form, which can
be used directly, e.g. Chemical structures, tables,
terminology.5.Full-text Databases: contains the
complete version of text of given publications.
Information from the. Primary sources has been
collected together and organized under subject
headings and authors in reference databases.
These can be accessed in a number of ways: 

ACCESS
• Searching online from a database mounted on a host computer
from IRS (information retrieval service). This requires a
password.
TO • By means of searchable compact disk CD-ROM database.
• Online information retrieval from databases is the acquisition of

DATABAS information from a distant computer via a terminal or PC,


involving dialogue between enquirer and computer.

ES:
• From a database with WWW interface mounted either locally or
available from a remote server.

Today CD-ROMs often are mounted on a server so


in reality the user will not be able to notice any
difference between using online databases or a CD-
ROM.

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