Cie Alevel Biology
Cie Alevel Biology
DNA replication
ATP Adaptation for Universal Energy Currency
NOTE
Energy does not come form breaking these bond,
but from changes in chemical potential energy.
Pi is a good leaving group, as ATP synthase can efficiently reattach the Pi to ADP to
form ATP (reversible).
Anaerobic
respiration
Aerobic respiration
• GLYCOLYSIS
• LINK REACTION (OXYGEN PRESENT)
• KREBS CYCLE (OXYGEN PRESENT)
• OXIDATIVE PHOSPHORYLATION (OXYGEN PRESENT)
Glycolysis
Pyruvate, still contains large amount of chemical potential energy therefore if oxygen is available,
then Krebs cycle and oxidative phosphorylation is continued to make use of this energy.
Link Reaction
Occurs in the matrix of mitochondrion therefore must require pyruvate to actively be transported into matrix
Coenzyme A is a complex molecule composed of nucleoside (adenine plus ribose) with Vitamin, it acts as a
carrier for acetyl groups (CH3-CO) to the Krebs cycle.
Krebs Cycle
Although reaction is part of aerobic respiration, the reactions make use of no oxygen as it is only necessary
for oxidative phosphorylation.
Acetyl (2C) CoA combines with Oxaloacetate (4C) to produce Citrate (6C).
Citrate is decarboxylated to produce CO2, and dehydrogenated to reduce NAD and FAD.
ADP + Pi ATP, also occurs while the protons pass through ATP synthase. This happens
by utilising the protons’ electrical potential energy for chemiosmosis.
The hydrogen from reduced NAD is passed to ethanol (CH3CHO); releasing the NAD
Irreversible reaction
Ethanal is reduced to ethanol by accepting hydrogen from reduced NAD, with the help of enzyme alcohol
dehydrogenase (this enzyme helps with removal of H from NADH)
Reaction cannot be reversed, and remaining chemical potential energy in ethanol is wasted
Lactic fermentation (conversion of glucose to lactate)
Reversible reaction
Pyruvate is decarboxylated by pyruvate decarboxylase into ethanal – which acts as a
hydrogen acceptor from reduced NAD
The post exercise uptake of extra oxygen to pay off oxygen deficiency which is needed for:
A high metabolic rate, as many organs are operating above resting level.
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