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    Hepatitis C

    Uploaded by

    Mohamed Ismail
    Dr. Eman Elmokadem

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd

    Hepatitis C

    Uploaded by

    Mohamed Ismail
    157 views15 pages
    Dr. Eman Elmokadem

    Copyright

    © © All Rights Reserved

    Available Formats

    PPTX, PDF, TXT or read online from Scribd

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    Dr. Eman Elmokadem

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    157 views15 pages

    Hepatitis C

    Uploaded by

    Mohamed Ismail
    Dr. Eman Elmokadem

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    You are on page 1of 15

    Hepatitis C

    Points to Discuss:
    • Definition.
    • Etiology.
    • Epidemiology.
    • Pathophysiology.
    • Diagnosis.
    • Investigations.
    • Complications.
    • Patient counseling & advice.
    Definition
     It is a viral infection disease caused by the hepatitis C virus (HCV) that
    primarily affects the liver (Hepatocytophilic).
     the virus can cause both acute and chronic hepatitis.

    Electron micrograph of Hepacivirus C purified from cell


    culture (30-60 nm).
    Etiology
    Hepatitis C is a blood borne infection and is caused by the hepatitis C virus (HCV).
    HCV can be transmitted by:

    • Needle stick injuries in healthcare.

    • Direct contact with infected blood or any body fluids.

    • I.V. injection abuse.

    • Sexual contact.

    • Blood transfusions.

    • Pregnancy (rare 5%).


    Epidemiology
    • Central and East Asia
    • Southeast Asia
    • North Africa
    • the Middle East
    • Central Latin America
    • Eastern Europe

    It is estimated 2% of people globally are living with hepatitis C.


    In Egypt it is estimated that prevalence of HCV is around 4.5% to 6.7%.
    Pathophysiology
    • Cell-mediated immune mechanism.
    • Production of antiviral cytokines by T-lymphocytes certainly
    play a role in hepatocytic injury due to HCV.
    Diagnosis
    hepatitis C is usually a silent infection for many years

    (jaundice)

    (anorexia)
    ns
    ti o
    g a
    st i
    v e
    In
    Liver biopsy

    Loss of lobular architecture (dysplasia) and


    irregular central hepatic vein
    Complications

    • Cirrhosis.

    • Esophageal varices.

    • Hepatic encephalopathy.

    • Liver failure.

    • Hepatocellular carcinoma (HCC).


    Liver cirrhosis

    HCC
    Esophageal varices
    endoscopy Video
    Patient counseling & advice

    Avoid donating blood


    Good hygiene
    Abstain from alcohol use

    Inform health-care workers beforehand about your HCV status Don’t share personal objects
    Course name: Pathology & pathophysiology.
    Course code: PHP – 221.
    Semester: Spring 2020.
    Group: B1.1
    Lab: D2.1

    Student ID

    Baraa Abdelaziz 20183771

    Menna tullah Wael 20181921 Lecture instructor:


    Assoc. Prof. Hayam Ateya.
    Moaz Khaled 20180813 L. Marwa Nagi.

    Mohamed Abdelmegeed 20180104 Lab instructor (T.A.):


    Dr. Eman Elmokadem.
    Rawan Waleed 20182559

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